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697 |
Mulyani E.Y., Hardinsyah, Briawan D., Santoso B.I., Jus'At I. |
57193083043;7409543837;56157628600;56653822500;6506270119; |
Effect of dehydration during pregnancy on birth weight and length in West Jakarta |
2021 |
Journal of Nutritional Science |
10 |
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e70 |
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https://www.scopus.com/inward/record.uri?eid=2-s2.0-85116628377&doi=10.1017%2fjns.2021.59&partnerID=40&md5=1de2e2cc37d1b69be0cd84f9859bffa5 |
Department of Nutrition, Faculty of Health Sciences, Esa Unggul University, Jalan Arjuna Utara No.9, West Jakarta, Kebon Jeruk, 11510, Indonesia; Department of Community Nutrition, Faculty of Human Ecology, Bogor Agricultural University, Bogor, Indonesia; Department of Obstetrics and Gynaecology, Faculty of Medicine, University of Indonesia, Dr. Cipto Mangunkusumo General Hospital, Depok, Indonesia |
Mulyani, E.Y., Department of Nutrition, Faculty of Health Sciences, Esa Unggul University, Jalan Arjuna Utara No.9, West Jakarta, Kebon Jeruk, 11510, Indonesia; Hardinsyah, Department of Community Nutrition, Faculty of Human Ecology, Bogor Agricultural University, Bogor, Indonesia; Briawan, D., Department of Community Nutrition, Faculty of Human Ecology, Bogor Agricultural University, Bogor, Indonesia; Santoso, B.I., Department of Obstetrics and Gynaecology, Faculty of Medicine, University of Indonesia, Dr. Cipto Mangunkusumo General Hospital, Depok, Indonesia; Jus'At, I., Department of Nutrition, Faculty of Health Sciences, Esa Unggul University, Jalan Arjuna Utara No.9, West Jakarta, Kebon Jeruk, 11510, Indonesia |
Nutrition and maternal behavior are critical factors in fetal development. Maternal water intake is necessary to regulate metabolism and may influence fetal growth. This study aims to determine the effect of dehydration during pregnancy on birth weight and length. This cohort-prospective study took place in the area of Kebon Jeruk District Health Centre. A total of 38 subjects of pregnant women in their second trimester were examined. Subject characteristics were collected through direct measurements and interviews. Urine and blood samples were collected at the sixth trimester (32-34 and 35-37 weeks) to determine hydration status. Nutritional status was collected through food recall, while birth weight and length were obtained from the anthropometric measurements 30 min after birth. From a total of 38 subjects, 20 were dehydrated, and 18 were well hydrated. There was a significant relationship between hydration status and water intake, birth weight and length, head circumference, and chest circumference. After being corrected to the level of water intake, the difference in birth weight and length between the two groups were 500.6 g and 0.4 cm, and 0.8 cm and 1.4 cm for the head circumference and chest circumference (P < 0.05). It is recommended for mothers to monitor their weight and ensure fluid intake of 3.0 l per day. Further research requires more subjects to observe the effects of chronic maternal dehydration on pregnancy output and a cohort study that monitors infant development in the first six months of life. © The Author(s), 2021. |
Dehydration; Fetal growth; Maternal nutrition; Pregnancy; Water intake |
biological marker; drinking water; adult; arm circumference; Article; birth length; birth weight; blood sampling; body temperature; calcium intake; caloric intake; carbohydrate intake; chest circumference; child development; clinical article; cohort analysis; controlled study; dehydration; dietary intake; fat intake; female; fluid intake; gestational age; head circumference; hip circumference; human; hydration status; Indonesia; iron intake; maternal nutrition; newborn; nutritional status; placenta weight; plasma osmolality; pregnancy; pregnancy outcome; pregnant woman; prospective study; protein intake; renal system parameters; second trimester pregnancy; serum osmolality; sodium blood level; systolic blood pressure; third trimester pregnancy; urine color; urine osmolality; urine sampling |
Cambridge University Press |
20486790 |
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34527228 |
Article |
Q1 |
749 |
6541 |
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702 |
Deviandri R., van der Veen H.C., Lubis A.M.T., Postma M.J., van den Akker-Scheek I. |
57222171014;57265936900;15122639800;7006296502;55936129400; |
Translation, Cross-Cultural Adaptation, Validity, and Reliability of the Indonesian Version of the IKDC Subjective Knee Form |
2021 |
Orthopaedic Journal of Sports Medicine |
9 |
9 |
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https://www.scopus.com/inward/record.uri?eid=2-s2.0-85116266022&doi=10.1177%2f23259671211038372&partnerID=40&md5=ce2114ff8fec736ec8dc0057566bccd5 |
Department of Orthopaedic Surgery, University of Groningen, University Medical Center Groningen, Groningen, Netherlands; Department of Physiology--Faculty of Medicine, Universitas Riau, Pekanbaru, Indonesia; Division of Orthopaedics--Sports Injury, Arifin Achmad Hospital, Pekanbaru, Indonesia; Department of Orthopaedics--Faculty of Medicine, Universitas Indonesia/Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Department of Health Sciences, University of Groningen, University Medical Center Groningen, Netherlands; Department of Economics, Econometrics and Finance, University of Groningen, Faculty of Economics Business, Groningen, Netherlands; Department of Pharmacology and Therapy, Universitas Airlangga, Surabaya, Indonesia; Center of Excellence in Higher Education for Pharmaceutical Care Innovation, Universitas Padjadjaran, Bandung, Indonesia |
Deviandri, R., Department of Orthopaedic Surgery, University of Groningen, University Medical Center Groningen, Groningen, Netherlands, Department of Physiology--Faculty of Medicine, Universitas Riau, Pekanbaru, Indonesia, Division of Orthopaedics--Sports Injury, Arifin Achmad Hospital, Pekanbaru, Indonesia; van der Veen, H.C., Department of Orthopaedic Surgery, University of Groningen, University Medical Center Groningen, Groningen, Netherlands; Lubis, A.M.T., Department of Orthopaedics--Faculty of Medicine, Universitas Indonesia/Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Postma, M.J., Department of Health Sciences, University of Groningen, University Medical Center Groningen, Netherlands, Department of Economics, Econometrics and Finance, University of Groningen, Faculty of Economics Business, Groningen, Netherlands, Department of Pharmacology and Therapy, Universitas Airlangga, Surabaya, Indonesia, Center of Excellence in Higher Education for Pharmaceutical Care Innovation, Universitas Padjadjaran, Bandung, Indonesia; van den Akker-Scheek, I., Department of Orthopaedic Surgery, University of Groningen, University Medical Center Groningen, Groningen, Netherlands |
Background: No questionnaire is currently available for use in patients with anterior cruciate ligament (ACL) injuries in an Indonesian population. The most-used questionnaire in clinical research for these patients is the International Knee Documentation Committee (IKDC) Subjective Knee Form, as its psychometric properties are considered to be excellent. Purpose: To translate the IKDC into Indonesian and assess its validity for use in Indonesian-speaking patients with ACL injuries. Study Design: Cohort study (diagnosis); Level of evidence, 2. Methods: After a forward-and-backward translation procedure and cross-cultural adaptation, the validity and reliability of the questionnaire were investigated. The responses of ACL injury patients on 3 questionnaires, the Indonesian-IKDC (I-IKDC), 36-Item Short Form Health Survey, and Kujala Anterior Knee Pain Scale, were compared. Following consensus-based standards for the selection of health measurement instruments guidelines, construct validity, test-retest reliability, internal consistency, floor and ceiling effects, and measurement error were determined. The Bland-Altman method was used to explore absolute agreement. Results: Of 253 ACL injury patients, 106 (42%) responded to the invitation. Construct validity was considered good, as all predefined hypotheses on correlations between the I-IKDC and other scores were confirmed. Reliability proved excellent, with a high test-retest correlation (intraclass correlation coefficient = 0.99). Bland-Altman analyses showed no systematic bias between test and retest. Internal consistency was good (Cronbach α =.90). There were no floor or ceiling effects. Standard error of measurement was 2.1, and the minimal detectable change was 5.8 at the individual level and 0.7 at the group level. Conclusion: The I-IKDC, as developed, appeared to be a good evaluation instrument for Indonesian patients with ACL injuries. © The Author(s) 2021. |
anterior cruciate ligament; IKDC; Indonesian version; reliability; validity |
adult; Article; controlled study; female; human; human experiment; human tissue; major clinical study; male; retrospective study |
SAGE Publications Ltd |
23259671 |
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Article |
Q1 |
1329 |
2772 |
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703 |
Massenburg B.B., Hopper R.A., Crowe C.S., Morrison S.D., Alonso N., Calis M., Donkor P., Kreshanti P., Yuan J. |
55859007400;57277146200;55976347800;45661573100;7004026436;53263345100;15063876600;36192866200;57278294200; |
Global Burden of Orofacial Clefts and the World Surgical Workforce |
2021 |
Plastic and Reconstructive Surgery |
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568E |
580E |
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1 |
https://www.scopus.com/inward/record.uri?eid=2-s2.0-85115936193&doi=10.1097%2fPRS.0000000000008334&partnerID=40&md5=b6aab0e1c64506de878c4f09a9d86d70 |
Division of Plastic and Reconstructive Surgery, University of Washington, Seattle, WA, United States; Division of Craniofacial and Plastic Surgery, Seattle Children's Hospital, Division of Plastic Surgery, Department of Surgery, University of São Paulo, São Paulo, Brazil; Department of Plastic, Reconstructive, and Aesthetic Surgery, Hacettepe University, Ankara, Turkey; Department of Surgery, Kwame Nkrumah University of Science and Technology, Kumasi, Ghana; Division of Plastic Reconstructive and Aesthetic Surgery, Department of Surgery, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Cleft and Craniofacial Center Dr. Cipto Mangunkusumo Hospital; and School of Medicine, Shanghai Jiao Tong University, Shanghai, China |
Massenburg, B.B., Division of Plastic and Reconstructive Surgery, University of Washington, Seattle, WA, United States; Hopper, R.A., Division of Plastic and Reconstructive Surgery, University of Washington, Seattle, WA, United States; Crowe, C.S., Division of Craniofacial and Plastic Surgery, Seattle Children's Hospital, Division of Plastic Surgery, Department of Surgery, University of São Paulo, São Paulo, Brazil; Morrison, S.D., Department of Plastic, Reconstructive, and Aesthetic Surgery, Hacettepe University, Ankara, Turkey; Alonso, N., Department of Plastic, Reconstructive, and Aesthetic Surgery, Hacettepe University, Ankara, Turkey; Calis, M., Department of Surgery, Kwame Nkrumah University of Science and Technology, Kumasi, Ghana; Donkor, P., Division of Plastic Reconstructive and Aesthetic Surgery, Department of Surgery, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Kreshanti, P., Cleft and Craniofacial Center Dr. Cipto Mangunkusumo Hospital; and School of Medicine, Shanghai Jiao Tong University, Shanghai, China; Yuan, J., Division of Plastic and Reconstructive Surgery, University of Washington, Seattle, WA, United States |
Background: Orofacial clefts are one of the most common congenital anomalies, but this disease burden is unevenly distributed worldwide. The authors hypothesize that this burden falls disproportionately on the countries with the smallest surgical workforce or lowest Socio-Demographic Index, rather than those with the highest prevalence of disease. Methods: The authors estimated the prevalence and disease burden of orofacial clefting from 1990 to 2017 in 195 countries using the Global Burden of Disease methodology. Prevalence and disability-adjusted life-years were compared geographically, temporally, and against the size of the national surgical workforce, Socio-Demographic Index, and income status. Linear and logarithmic regressions were performed. Results: In 2017, the prevalence of orofacial clefting was estimated to be 10.8 million people, representing a disease burden of 652,084 disability-adjusted life-years, with most of this disease burden experienced by low- and middle-income countries (94.1%). From 1990 to 2017, there was a decrease in disease burden (-70.2%) and prevalence (-4.9%). There was negative logarithmic association between surgical workforce size and disease burden, with a surgical workforce of greater than six providers per 100,000 population (3.6 disability-adjusted life-years versus 22.4 disability-adjusted life-years per 100,000 population; p < 0.0001). Conclusions: Burden of orofacial clefting has a strong negative association with the size of the surgical workforce, suggesting that strengthening the surgical workforce will help alleviate this burden. Epidemiologic data on countries and regions with inadequate surgical workforces and high disease burden should guide future research efforts and allocation of resources, and guide the treatment and educational goals of international charitable organizations. © 2021 Lippincott Williams and Wilkins. All rights reserved. |
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cleft lip; cleft palate; global disease burden; global health; health service; human; organization and management; prevalence; reconstructive surgery; Cleft Lip; Cleft Palate; Global Burden of Disease; Global Health; Health Services Needs and Demand; Health Workforce; Humans; Prevalence; Reconstructive Surgical Procedures |
Lippincott Williams and Wilkins |
00321052 |
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34550940 |
Article |
Q1 |
1841 |
1560 |
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705 |
Muharam R., Sumapraja K., Pratama G., Azyati M., Prabowo K.A. |
57191492732;55819683500;57195959221;57274785700;57224859187; |
Impact of ivf on the timing and symptoms of menopause |
2021 |
International Journal of Women's Health |
13 |
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889 |
893 |
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https://www.scopus.com/inward/record.uri?eid=2-s2.0-85115838581&doi=10.2147%2fIJWH.S322718&partnerID=40&md5=6d1216144e47b8cdba986eef18fc94e5 |
Department of Obstetrics & Gynecology, Faculty of Medicine, University of Indonesia, Cipto Mangunkusumo National Hospital, Jakarta, Indonesia |
Muharam, R., Department of Obstetrics & Gynecology, Faculty of Medicine, University of Indonesia, Cipto Mangunkusumo National Hospital, Jakarta, Indonesia; Sumapraja, K., Department of Obstetrics & Gynecology, Faculty of Medicine, University of Indonesia, Cipto Mangunkusumo National Hospital, Jakarta, Indonesia; Pratama, G., Department of Obstetrics & Gynecology, Faculty of Medicine, University of Indonesia, Cipto Mangunkusumo National Hospital, Jakarta, Indonesia; Azyati, M., Department of Obstetrics & Gynecology, Faculty of Medicine, University of Indonesia, Cipto Mangunkusumo National Hospital, Jakarta, Indonesia; Prabowo, K.A., Department of Obstetrics & Gynecology, Faculty of Medicine, University of Indonesia, Cipto Mangunkusumo National Hospital, Jakarta, Indonesia |
Background: Age-related loss of female fertility is characterized by a decline in both the quantity and quality of ovarian follicles. Symptoms of ovarian stimulation, which is part of the process of in vitro fertilization (IVF), vary among women. This study was conducted to analyze the differences in menopausal timing and symptoms in women who had undergone IVF compared to those who had natural pregnancies. Methodology: In this cross-sectional study, menopausal women were categorized into two groups: those who had undergone IVF (n = 50) and those who had not (n = 50). Clinical data were obtained from the participants’ medical records, and patient interviews were conducted using the menopause rating scale (MRS) questionnaires. Results: The IVF had no significant impact on psychological or somatic symptoms in either group (p>0.05). However, it affected urogenital symptoms (p<0.05). Additionally, there was a significant difference in the age of onset of menopause between the groups (p<0.05). Conclusion: There is a significant correlation between IVF treatment, urogenital symptoms in menopause, and the age of onset of menopause. © 2021 Muharam et al. This work is published and licensed by Dove Medical Press Limited. |
In vitro fertilization; Infertility; Menopause; Psychological symptoms; Urogenital |
adult; anxiety; arthralgia; Article; bladder dysfunction; clinical article; cross-sectional study; depression; exhaustion; female; hot flush; human; in vitro fertilization; irritability; menopause; menopause rating scale; middle aged; myalgia; onset age; rating scale; risk factor; sexual dysfunction; sleep disorder; vaginal dryness |
Dove Medical Press Ltd |
11791411 |
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Article |
Q1 |
1136 |
3603 |
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726 |
Kim Y., Ahmed E., Ascher N., Danguilan R., Hooi L.S., Hustrini N.M., Kim Y.H., Kute V., Rosete-Liquete R.M.O., Ma M., Mannon R.B., Nakagawa Y., Od-Erdne L., Ramesh V., Rashid H.U., Thangaraju S., Thwin K.T., Vathsala A., West L., Win K.K., Ahn C., Wong G. |
57194114108;57209626753;35394192500;56073507800;6603696990;57200424892;7410196419;36632470600;6507576169;37034386700;7003807110;57236289600;57236003300;57205980938;7102095343;57192114135;57193627441;7003714214;7103226990;57235723800;7201986669;23974794800; |
Meeting Report: First State of the Art Meeting on Gender Disparity in Kidney Transplantation in the Asia-Pacific |
2021 |
Transplantation |
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1888 |
1891 |
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https://www.scopus.com/inward/record.uri?eid=2-s2.0-85113766902&doi=10.1097%2fTP.0000000000003841&partnerID=40&md5=9bfb17e13ffa1ac91810ab03036b4871 |
Department of Internal Medicine, Inje University, Busan Paik Hospital, Busan, South Korea; Department of Nephrology, Sindh Institute of Urology and Transplantation, Karachi, Pakistan; Division of Transplant Surgery, University of California San Francisco, San Francisco, CA, United States; National Kidney and Transplant Institute, Manila, Quezon City, Philippines; Department of Nephrology and Medicine, Sultanah Aminah Hospital, Johor Bahru, Malaysia; Department of Internal Medicine, Faculty of Medicine, Universitas Indonesia, Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Department of Internal Medicine, Inje University, Busan Paik Hospital, Busan, South Korea; Nephrology and Transplantation, Institute of Kidney Diseases and Research Center, Dr. HL Trivedi Institute of Transplantation Sciences (IKDRC-ITS), Gujarat University of Transplantation, Sciences, Ahmedabad, India; National Kidney and Transplant Institute, Philippines; Department of Medicine, Queen Mary Hospital, Hong Kong, Hong Kong; Division of Nephrology, Department of Medicine, University of Nebraska Medical Center, Omaha, NE, United States; Division of Urology, Juntendo University, Tokyo, Japan; Department of Nephrology, First Central Hospital of Mongolia, Organ Transplantation Center, Ulaanbaatar, Mongolia; National Organ and Tissue Transplant Organisation, DGHS, Ministry of Health and Family Welfare, Vardhman Mahavir Medical College, Safdarjung Hospital, New Delhi, India; Department of Nephrology, Kidney Foundation Hospital and Research Institute, Dhaka, Bangladesh; Department of Renal Medicine, Singapore General Hospital, Singapore, Singapore; Department of Renal Medicine, University of Medicine (I), Yangon, Myanmar; Division of Nephrology, National University of Singapore, Singapore, Singapore; Department of Pediatrics, University of Alberta, Edmonton, AB, Canada; Department of Nephrology, Specialty Hospital, Yangon, Myanmar; Division of Nephrology, National Medical Center, Seoul, South Korea; Sydney School of Public Health, University of Sydney, Sydney, NSW, Australia; Centre for Renal and Transplant Research, Westmead Hospital, Sydney, NSW, Australia |
Kim, Y., Department of Internal Medicine, Inje University, Busan Paik Hospital, Busan, South Korea; Ahmed, E., Department of Nephrology, Sindh Institute of Urology and Transplantation, Karachi, Pakistan; Ascher, N., Division of Transplant Surgery, University of California San Francisco, San Francisco, CA, United States; Danguilan, R., National Kidney and Transplant Institute, Manila, Quezon City, Philippines; Hooi, L.S., Department of Nephrology and Medicine, Sultanah Aminah Hospital, Johor Bahru, Malaysia; Hustrini, N.M., Department of Internal Medicine, Faculty of Medicine, Universitas Indonesia, Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Kim, Y.H., Department of Internal Medicine, Inje University, Busan Paik Hospital, Busan, South Korea; Kute, V., Nephrology and Transplantation, Institute of Kidney Diseases and Research Center, Dr. HL Trivedi Institute of Transplantation Sciences (IKDRC-ITS), Gujarat University of Transplantation, Sciences, Ahmedabad, India; Rosete-Liquete, R.M.O., National Kidney and Transplant Institute, Philippines; Ma, M., Department of Medicine, Queen Mary Hospital, Hong Kong, Hong Kong; Mannon, R.B., Division of Nephrology, Department of Medicine, University of Nebraska Medical Center, Omaha, NE, United States; Nakagawa, Y., Division of Urology, Juntendo University, Tokyo, Japan; Od-Erdne, L., Department of Nephrology, First Central Hospital of Mongolia, Organ Transplantation Center, Ulaanbaatar, Mongolia; Ramesh, V., National Organ and Tissue Transplant Organisation, DGHS, Ministry of Health and Family Welfare, Vardhman Mahavir Medical College, Safdarjung Hospital, New Delhi, India; Rashid, H.U., Department of Nephrology, Kidney Foundation Hospital and Research Institute, Dhaka, Bangladesh; Thangaraju, S., Department of Renal Medicine, Singapore General Hospital, Singapore, Singapore; Thwin, K.T., Department of Renal Medicine, University of Medicine (I), Yangon, Myanmar; Vathsala, A., Division of Nephrology, National University of Singapore, Singapore, Singapore; West, L., Department of Pediatrics, University of Alberta, Edmonton, AB, Canada; Win, K.K., Department of Nephrology, Specialty Hospital, Yangon, Myanmar; Ahn, C., Division of Nephrology, National Medical Center, Seoul, South Korea; Wong, G., Sydney School of Public Health, University of Sydney, Sydney, NSW, Australia, Centre for Renal and Transplant Research, Westmead Hospital, Sydney, NSW, Australia |
[No abstract available] |
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Lippincott Williams and Wilkins |
00411337 |
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34416749 |
Article |
Q1 |
1450 |
2398 |
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731 |
Raharjo D.E., Kunadian V. |
57212958767;55390915800; |
Is There a Difference in Efficacy of Percutaneous Coronary Intervention for Focal and Diffuse Stable Coronary Artery Disease? |
2021 |
Circulation: Cardiovascular Interventions |
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011013 |
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https://www.scopus.com/inward/record.uri?eid=2-s2.0-85113224581&doi=10.1161%2fCIRCINTERVENTIONS.121.011013&partnerID=40&md5=d51bf48934551b00e2a6df5c69fb0e80 |
Translational and Clinical Research Institute, Newcastle University, Newcastle upon Tyne, United Kingdom; Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Cardiothoracic Centre, Freeman Hospital, Newcastle Upon Tyne Hospitals NHS Foundation Trust, United Kingdom |
Raharjo, D.E., Translational and Clinical Research Institute, Newcastle University, Newcastle upon Tyne, United Kingdom, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Kunadian, V., Translational and Clinical Research Institute, Newcastle University, Newcastle upon Tyne, United Kingdom, Cardiothoracic Centre, Freeman Hospital, Newcastle Upon Tyne Hospitals NHS Foundation Trust, United Kingdom |
[No abstract available] |
coronary artery disease; Editorials; heart disease; morbidity; percutaneous coronary intervention |
adverse event; coronary artery bypass graft; coronary artery disease; diagnostic imaging; human; percutaneous coronary intervention; Coronary Artery Bypass; Coronary Artery Disease; Humans; Percutaneous Coronary Intervention |
Lippincott Williams and Wilkins |
19417640 |
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34340524 |
Review |
Q1 |
2621 |
832 |
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733 |
Maulani C., C Masulili S.L., Santoso W.D., Soedarsono N., Kusdhany L., Auerkari E.I. |
57205060934;57226076327;6506080422;14049161500;55301180900;10139113000; |
Association of subgingival Epstein-Barr virus and periodontitis |
2021 |
F1000Research |
10 |
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414 |
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https://www.scopus.com/inward/record.uri?eid=2-s2.0-85112635068&doi=10.12688%2ff1000research.52624.1&partnerID=40&md5=0f76116d02cb7eb0372cd72bb0c00912 |
Faculty of Dentistry, Universitas IndonesiaJakarta 10430, Indonesia; Department of Periodontology, Faculty of Dentistry, Universitas IndonesiaJakarta 10430, Indonesia; Department of Internal Medicine, Faculty of Medicine, Universitas IndonesiaJakarta 10430, Indonesia; Department of Oral Biology, Faculty of Dentistry, Universitas IndonesiaJakarta 10430, Indonesia; Department of Prosthodontics, Faculty of Dentistry, Universitas IndonesiaJakarta 10430, Indonesia |
Maulani, C., Faculty of Dentistry, Universitas IndonesiaJakarta 10430, Indonesia; C Masulili, S.L., Department of Periodontology, Faculty of Dentistry, Universitas IndonesiaJakarta 10430, Indonesia; Santoso, W.D., Department of Internal Medicine, Faculty of Medicine, Universitas IndonesiaJakarta 10430, Indonesia; Soedarsono, N., Department of Oral Biology, Faculty of Dentistry, Universitas IndonesiaJakarta 10430, Indonesia; Kusdhany, L., Department of Prosthodontics, Faculty of Dentistry, Universitas IndonesiaJakarta 10430, Indonesia; Auerkari, E.I., Department of Oral Biology, Faculty of Dentistry, Universitas IndonesiaJakarta 10430, Indonesia |
Background: The Epstein-Barr virus (EBV) is gaining interest as a possible agent in the etiology of periodontitis. Previous studies have shown controversy on whether EBV DNA in the subgingival periodontal pockets is associated with periodontitis. The aim of the present study was to seek the potential relationship between EBV and periodontitis. Methods: Data on socio-demographics, oral health, and periodontal health were recorded, and samples were collected from gingival crevicular fluid, using sterile paper point. This case-control study of 118 participants included 59 subjects with severe periodontitis and 59 control subjects with mild periodontitis. The EBV load was determined by quantitative real-time PCR. Results: EBV DNA was detected in 37.3% of the case samples and in 18.6% of the control samples. There was no significant difference in the load of EBV DNA between severe and mild periodontitis (p>0.05). The observed load of EBV DNA was up to 4.55x10 5 copies/mL. The detected EBV DNA was significantly associated with the plaque index and the oral hygiene index (all p<0.05). Conclusions: A significant association was not found, but EBV might contribute to periodontitis. Gingival crevicular fluid is useful for monitoring the EBV load by the real-time PCR technique. Copyright: © 2021 Maulani C et al. |
Epstein-Barr Virus; Gingival Crevicular Fluid; Periodontitis |
virus DNA; case control study; complication; Epstein Barr virus; Epstein Barr virus infection; human; periodontitis; Case-Control Studies; DNA, Viral; Epstein-Barr Virus Infections; Herpesvirus 4, Human; Humans; Periodontitis |
NLM (Medline) |
20461402 |
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34316360 |
Article |
Q1 |
1099 |
3793 |
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758 |
Auerkari E.I., Maulani C., C. Masulili S.L., Santoso W.D., Soedarsono N., Kusdhany L. |
10139113000;57205060934;57226076327;6506080422;14049161500;55301180900; |
Association of subgingival Epstein-Barr virus and periodontitis |
2021 |
F1000Research |
10 |
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414 |
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https://www.scopus.com/inward/record.uri?eid=2-s2.0-85110298348&doi=10.12688%2ff1000research.52624.2&partnerID=40&md5=d21a6f40dceec542152f1e950acf5922 |
Faculty of Dentistry, Universitas Indonesia, Jakarta, 10430, Indonesia; Department of Periodontology, Faculty of Dentistry, Universitas Indonesia, Jakarta, 10430, Indonesia; Department of Internal Medicine, Faculty of Medicine, Universitas Indonesia, Jakarta, 10430, Indonesia; Department of Oral Biology, Faculty of Dentistry, Universitas Indonesia, Jakarta, 10430, Indonesia; Department of Prosthodontics, Faculty of Dentistry, Universitas Indonesia, Jakarta, 10430, Indonesia |
Auerkari, E.I., Department of Oral Biology, Faculty of Dentistry, Universitas Indonesia, Jakarta, 10430, Indonesia; Maulani, C., Faculty of Dentistry, Universitas Indonesia, Jakarta, 10430, Indonesia; C. Masulili, S.L., Department of Periodontology, Faculty of Dentistry, Universitas Indonesia, Jakarta, 10430, Indonesia; Santoso, W.D., Department of Internal Medicine, Faculty of Medicine, Universitas Indonesia, Jakarta, 10430, Indonesia; Soedarsono, N., Department of Oral Biology, Faculty of Dentistry, Universitas Indonesia, Jakarta, 10430, Indonesia; Kusdhany, L., Department of Prosthodontics, Faculty of Dentistry, Universitas Indonesia, Jakarta, 10430, Indonesia |
Background: The Epstein-Barr virus (EBV) is gaining interest as a possible agent in the etiology of periodontitis. Previous studies have shown controversy on whether EBV DNA in the subgingival periodontal pockets is associated with periodontitis. The present study aimed to seek the potential relationship between EBV and periodontitis. Methods: Samples were taken from gingival crevicular fluid using sterile paper points, and data on sociodemographics, oral health, and periodontal health were recorded. This case-control study of 118 participants included 59 subjects with severe periodontitis and 59 control subjects with mild periodontitis. Quantitative real-time PCR was used to determined EBV load. Results: EBV DNA was detected in 37.3% of the case samples and 18.6% of the control samples. There was no significant difference in a load of EBV DNA between severe and mild periodontitis (p>0.05). The observed load of EBV DNA was up to 4.55x10 5 copies/mL. The detected EBV DNA was significantly associated with the plaque index and the oral hygiene index (p<0.05). Conclusions: Although no significant association was found, EBV may play a role in periodontitis. The real-time PCR methods can be used to monitor the EBV load in gingival crevicular fluid. © 2021 Maulani C et al. |
Epstein-Barr Virus; Gingival Crevicular Fluid; Periodontitis |
adult; aged; Article; case control study; cementoenamel junction; clinical attachment level; controlled study; demography; dental caries; DNA extraction; enzyme immunoassay; Epstein Barr virus; female; gingiva bleeding; gingivitis; health; human; hygiene; lactation; major clinical study; male; mouth hygiene; nonhuman; oral hygiene index; oral hygiene index simplified; peer review; periodontal pocket depth; periodontitis; plaque index; proteomics; real time polymerase chain reaction; regulatory T lymphocyte; tooth root canal |
F1000 Research Ltd |
20461402 |
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34316360 |
Article |
Q1 |
1099 |
3793 |
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767 |
Bachtiar E.W., Bachtiar B.M., Theodorea C.F., Tahapary D.L., Astrella C., Natalina N. |
6507328763;15831189400;57190048861;55944492500;57210793320;57225210620; |
A pilot study of red complex and three genera subgingival microbiome in periodontitis subjects with and without diabetes, evaluated by MinION platform |
2021 |
F1000Research |
10 |
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79 |
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1 |
https://www.scopus.com/inward/record.uri?eid=2-s2.0-85109577307&doi=10.12688%2ff1000research.28216.3&partnerID=40&md5=83c85f319460a8e5631506acfe142095 |
Department of Oral Biology and Oral Science Research Center, Faculty of Dentistry, Universitas Indonesia, Jakarta, 10430, Indonesia; Division of Endocrinology, Department of Internal Medicine, Dr. Cipto Mangunkusumo National Referral Hospital, Faculty of Medicine, Universitas Indonesia, Jakarta, 10430, Indonesia; Metabolic, Cardiovascular and Aging Cluster, The Indonesian Medical Education and Research Institute, Faculty of Medicine, Universitas Indonesia, Jakarta, 10430, Indonesia; Department of Internal Medicine, Dr. Cipto Mangunkusumo National Referral Hospital, Faculty of Medicine, Universitas Indonesia, Jakarta, 10430, Indonesia; Department of Periodontology, Faculty of Dentistry, Universitas Indonesia, Jakarta, 10430, Indonesia |
Bachtiar, E.W., Department of Oral Biology and Oral Science Research Center, Faculty of Dentistry, Universitas Indonesia, Jakarta, 10430, Indonesia; Bachtiar, B.M., Department of Oral Biology and Oral Science Research Center, Faculty of Dentistry, Universitas Indonesia, Jakarta, 10430, Indonesia; Theodorea, C.F., Department of Oral Biology and Oral Science Research Center, Faculty of Dentistry, Universitas Indonesia, Jakarta, 10430, Indonesia; Tahapary, D.L., Division of Endocrinology, Department of Internal Medicine, Dr. Cipto Mangunkusumo National Referral Hospital, Faculty of Medicine, Universitas Indonesia, Jakarta, 10430, Indonesia, Metabolic, Cardiovascular and Aging Cluster, The Indonesian Medical Education and Research Institute, Faculty of Medicine, Universitas Indonesia, Jakarta, 10430, Indonesia; Astrella, C., Metabolic, Cardiovascular and Aging Cluster, The Indonesian Medical Education and Research Institute, Faculty of Medicine, Universitas Indonesia, Jakarta, 10430, Indonesia, Department of Internal Medicine, Dr. Cipto Mangunkusumo National Referral Hospital, Faculty of Medicine, Universitas Indonesia, Jakarta, 10430, Indonesia; Natalina, N., Department of Periodontology, Faculty of Dentistry, Universitas Indonesia, Jakarta, 10430, Indonesia |
Background: Subgingival niche is one biofilm habitat containing rich microbiota, which plays an active role in maintaining the health of periodontal tissue and determining host response. As such, a study of changing subgingival biofilms is important for understanding the effect of a systemic condition. In this study, we compared the occurrence of six bacteria cohabiting in the subgingival area of periodontitis subjects, with (DP, n = 8) and without (NDP, n = 4) diabetes. Methods: The six genus and species of targeted bacteria were confirmed by 16S rRNA amplicon sequencing on MinION nanopore platform. Descriptive statistic was used to describe the obtained data. Results: We found that the six genus and species of targeted bacteria were detected but in different quantities in either group's periodontal pocket. Our data showed that Tannerella forsythia was the most abundant species in subgingival biofilms of the DP group of the red complex bacteria. In contrast, Aggregatibacter sp., which belongs to the phylum of proteobacteria, was present at a relatively lower level. In contrast, Fusobacterium sp., which belongs to orange complex bacteria, showed relative similarities in subgingival biofilms of both groups tested, while Veillonella sp., were abundant in the DP groups. Conclusions: Our data show that the diversity of classic periodontopathogens increased in the subgingival niche of periodontitis subjects with diabetes. It is the first study in Indonesia to apply MinION-based, full-length 16S rRNA amplicon sequencing in periodontitis patients with and without diabetes. © 2021 Bachtiar BM et al. |
16S rRNA; Diabetes; MinION; Periodontitis; Red Complex bacteria; Subgingival Microbiome |
RNA 16S; diabetes mellitus; genetics; gingiva; human; Indonesia; microflora; periodontitis; pilot study; Diabetes Mellitus; Gingiva; Humans; Indonesia; Microbiota; Periodontitis; Pilot Projects; RNA, Ribosomal, 16S |
F1000 Research Ltd |
20461402 |
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34249333 |
Article |
Q1 |
1099 |
3793 |
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783 |
Prabowo K.A., Ellenzy G., Wijaya M.C., Kloping Y.P. |
57224859187;57224861188;57221739074;57205266766; |
Impact of Work from Home Policy during the COVID-19 Pandemic on Mental Health and Reproductive Health of Women in Indonesia |
2021 |
International Journal of Sexual Health |
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1 |
https://www.scopus.com/inward/record.uri?eid=2-s2.0-85108422054&doi=10.1080%2f19317611.2021.1928808&partnerID=40&md5=0d311414603955c5b93af73ca9ec0c60 |
Faculty of Medicine, Airlangga University, Surabaya, Indonesia; Department of Psychiatry, Faculty of Medicine, University of Indonesia, Jakarta, Indonesia |
Prabowo, K.A., Faculty of Medicine, Airlangga University, Surabaya, Indonesia; Ellenzy, G., Department of Psychiatry, Faculty of Medicine, University of Indonesia, Jakarta, Indonesia; Wijaya, M.C., Faculty of Medicine, Airlangga University, Surabaya, Indonesia; Kloping, Y.P., Faculty of Medicine, Airlangga University, Surabaya, Indonesia |
Objectives: This study aimed to assess the impact of work from home (WFH) during the COVID-19 pandemic on the mental health and reproductive health of women in Indonesia. To the best of our knowledge, this is the first study evaluating the impact of WFH policy on said health aspects in Indonesia. Methods: We conducted an observational study with a cross-sectional approach using an online survey among premenopausal married women in Indonesia. The survey included the General Health Questionnaire (GHQ-12) for psychological distress, average sexual intercourse frequency (SIF) per week, contraception use, change of menstrual pattern, and desire for having children. To analyze the effect of WFH, the participants were divided into groups based on their WFH compliance: (1) Both couples (her and her spouse) work from home, (2) Only the wife works from home, (3) Only the husband works from home, and (4) Neither works from home. Results: 348 women were included in this study. Psychological distress occurred in 48.0% (n = 167) participants. No significant difference was found between the WFH groups (χ 2[3, N = 348] = 2.077, p =.56)). The average weekly SIF was found to be significantly fewer during WFH (T = 5014, z = −5.598, p <.001). However, only 22.7% (n = 79) participants reported the use of contraception and 52.9% (n = 196) participants still wanted to have children. Change of menstrual pattern occurred in 31.6% (n = 110) participants and were significantly correlated to psychological distress (rs =.126, p =.018). Conclusions: WFH does not aggravate the effect of the pandemic on women's mental and reproductive health in Indonesia. A significant number of them still desire to have children and contraceptive prevalence is low. © 2021 Taylor & Francis Group, LLC. |
COVID-19; mental health; pandemic; Quarantine; reproductive health |
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Routledge |
19317611 |
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Article |
Q1 |
809 |
5958 |
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