No records
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446 |
Damanik J., Yunir E. |
57211582841;36520254800; |
Type 2 Diabetes Mellitus and Cognitive Impairment |
2021 |
Acta medica Indonesiana |
53 |
2 |
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213 |
220 |
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https://www.scopus.com/inward/record.uri?eid=2-s2.0-85111560209&partnerID=40&md5=8b6a3af63f3b7bd6c8c50f2cf6ec2509 |
Department of Internal Medicine, Faculty of Medicine Universitas Indonesia - Cipto Mangunkusumo HospitalJakarta, Indonesia |
Damanik, J., Department of Internal Medicine, Faculty of Medicine Universitas Indonesia - Cipto Mangunkusumo HospitalJakarta, Indonesia; Yunir, E. |
Type 2 diabetes mellitus (T2DM) is strongly associated with lower performance on multiple domains of cognitive function and with structural abnormalities of the brain. With the growing epidemic of diabetes and aging population, neural complications of diabetes are expected to rise and becoming a challenge for future health implications. Understanding pathophysiology, factors associated with this complication, manifestation of cognitive impairment and various metabolic and neuroradiologic markers suggestive of this pathologic condition is crucial for proper management of this potentially debilitating complication of T2DM. This review will discuss briefly important aspects of cognitive impairment in T2DM. |
cognitive impairment; type 2 diabetes mellitus |
biological marker; aged; brain; cognition; human; non insulin dependent diabetes mellitus; pathology; pathophysiology; Aged; Biomarkers; Brain; Cognition; Diabetes Mellitus, Type 2; Humans |
NLM (Medline) |
01259326 |
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34251351 |
Review |
Q3 |
321 |
14162 |
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447 |
Nugroho P., Lydia A., Suhardjono S., Harimurti K. |
55987056300;8451287200;57218776121;23473513200; |
Association of BsmI Polymorphisms in the Vitamin D Receptor Gene Among Indonesian Population with Diabetic Kidney Disease |
2021 |
Acta medica Indonesiana |
53 |
2 |
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149 |
155 |
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https://www.scopus.com/inward/record.uri?eid=2-s2.0-85111468637&partnerID=40&md5=791ec67dac5f5065a522a04484329da4 |
Division of Nephrology and Hypertension, Indonesia. 2. Clinical Epidemiology Unit, Department of Internal Medicine, Faculty of Medicine, Universitas Indonesia-Dr Cipto Mangunkusumo HospitalJakarta, Indonesia |
Nugroho, P., Division of Nephrology and Hypertension, Indonesia. 2. Clinical Epidemiology Unit, Department of Internal Medicine, Faculty of Medicine, Universitas Indonesia-Dr Cipto Mangunkusumo HospitalJakarta, Indonesia; Lydia, A.; Suhardjono, S.; Harimurti, K. |
BACKGROUND: Diabetic kidney disease (DKD), as a common cause of end-stage renal disease (ESRD), is a chronic complication of diabetes mellitus (DM). It has been established that vitamin D deficiency is one of DKD risk factors, which may be related to vitamin D receptor (VDR) polymorphisms. This study aimed to analyze the association between VDR polymorphisms and DKD in Indonesian population, also risk factors that influence it. METHODS: a cross-sectional study was conducted in Type 2 DM patients who visited internal medicine outpatient clinic at Dr. Cipto Mangunkusumo Hospital, Jakarta, from November 2014 until March 2015. Data collection includes characteristics of subjects and laboratory examination, including BsmI polymorphisms in the vitamin D receptor gene. Patients with acute and severe disease were excluded from the study. Bivariate and multivariate analyses were done. RESULTS: of 93 DM subjects, 42 (45.2%) subjects were without DKD and 51 (54.8%) subjects had DKD. Most of the subjects had the Bb genotype (89.2%), with no subject having the BB genotype. The proportions of the B and b alleles were 44.6% and 55.4%, respectively. There is no association between BsmI polymorphisms in the vitamin D receptor gene and DKD (OR = 1.243; CI 95% 0.334-4.621; p value = 0.751). CONCLUSION: the profile of BsmI polymorphisms in the vitamin D receptor gene in the Indonesian population were genotypes Bb (89.2%) and bb (10.8%). There was no association between BsmI polymorphisms in the vitamin D receptor gene and DKD. Duration of DM more than five years influenced the association between those variables. |
BsmI; diabetic kidney disease; Indonesia-Malay race; polymorphisms; vitamin D receptor (VDR) gene |
calcitriol receptor; VDR protein, human; aged; blood; case control study; complication; cross-sectional study; diabetic nephropathy; female; genetic polymorphism; genetics; genotype; human; Indonesia; male; middle aged; non insulin dependent diabetes mellitus; risk factor; very elderly; Aged; Aged, 80 and over; Case-Control Studies; Cross-Sectional Studies; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Female; Genotype; Humans; Indonesia; Male; Middle Aged; Polymorphism, Genetic; Receptors, Calcitriol; Risk Factors |
NLM (Medline) |
01259326 |
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34251342 |
Article |
Q3 |
321 |
14162 |
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448 |
Syam A.F., Pitoyo C.W., Suhendro S., Zulkarnain B., Indrasari N.D., Aditianingsih D., Irawan C., Susilo A., Rumende C.M., Wijaya I.P., Ibrahim F., Rasmin M., Alwi I., Makmun D. |
8443384400;26022606900;8443626100;57226403717;6506289872;56312263600;28767651600;57217867079;14325966300;57221504958;57226400046;15754578700;15055173800;16638046900; |
Tocilizumab as a Treatment for 'Cytokine Storm Syndrome' in COVID-19: A Case Report |
2021 |
Acta medica Indonesiana |
53 |
2 |
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194 |
201 |
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https://www.scopus.com/inward/record.uri?eid=2-s2.0-85111460182&partnerID=40&md5=9fddc7ae8a7dbf93ea0a07158c0ab2b2 |
Fellow of the American College of Physicians; Division of Gastroenterology, Dept. of Internal Medicine, Faculty of Medicine Universitas Indonesia - Cipto Mangunkusumo Hospital, Jakarta, Indonesia |
Syam, A.F., Fellow of the American College of Physicians; Division of Gastroenterology, Dept. of Internal Medicine, Faculty of Medicine Universitas Indonesia - Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Pitoyo, C.W.; Suhendro, S.; Zulkarnain, B.; Indrasari, N.D.; Aditianingsih, D.; Irawan, C.; Susilo, A.; Rumende, C.M.; Wijaya, I.P.; Ibrahim, F.; Rasmin, M.; Alwi, I.; Makmun, D. |
Coronavirus disease 19 (COVID-19) which is caused by Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2), has been a problem worldwide, particularly due to the high rate of transmission and wide range of clinical manifestations. Acute respiratory distress syndrome (ARDS) and multiorgan failure are the most common events observed in severe cases and can be fatal. Cytokine storm syndrome emerges as one of the possibilities for the development of ARDS and multiorgan failure in severe cases of COVID-19. This case report describes a case of a 53-year-old male patient who has been diagnosed with COVID-19. Further evaluation in this patient showed that there was a marked increase in IL-6 level in blood accompanied with hyperferritinemia, which was in accordance with the characteristic of cytokine storm syndrome. Patient was treated with tocilizumab, a monoclonal antibody and is an antagonist to IL-6 receptor. The binding between tocilizumab and IL-6 receptors effectively inhibit and manage cytokine storm syndrome. Although this case report reported the efficacy of tocilizumab in managing cytokine storm syndrome, tocilizumab has several adverse effects requiring close monitoring. Further clinical randomized control trial is required to evaluate the efficacy and safety of tocilizumab administration in participants with various clinical characteristics and greater number of subjects. |
acute respiratory distress syndrome (ARDS); COVID-19; SARS-CoV-2; Tocilizumab |
biological marker; interleukin 6; monoclonal antibody; tocilizumab; blood; case report; complication; cytokine release syndrome; human; male; middle aged; Antibodies, Monoclonal, Humanized; Biomarkers; COVID-19; Cytokine Release Syndrome; Humans; Interleukin-6; Male; Middle Aged; SARS-CoV-2 |
NLM (Medline) |
01259326 |
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34251348 |
Article |
Q3 |
321 |
14162 |
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449 |
Rumende C.M. |
14325966300; |
Pulmonary Fibrosis Caused by Severe COVID-19 Infection: Discharge May Not Be The End of Treatment |
2021 |
Acta medica Indonesiana |
53 |
2 |
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141 |
142 |
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https://www.scopus.com/inward/record.uri?eid=2-s2.0-85111424385&partnerID=40&md5=313ffbbdaf35e6b4ca2305e0cfcfa1a4 |
Department of Internal Medicine, Faculty of Medicine Universitas Indonesia - Cipto Mangunkusumo HospitalJakarta, Indonesia |
Rumende, C.M., Department of Internal Medicine, Faculty of Medicine Universitas Indonesia - Cipto Mangunkusumo HospitalJakarta, Indonesia |
Since December 2019, COVID-19 caused by SARS-CoV-2 infection has been spread rapidly in the world. Beside acute respiratory distress syndrome found in acute phase of infection, there is also pulmonary fibrosis as a chronic complication due to COVID-19. With the global pandemic of COVID-19, more and more autopsy and puncture histopathological results have been published.Until now there is no specific therapy to handle post-inflammatory pulmonary fibrosis due to COVID-19 infection. Several studies are ongoing to determine an effective treatment for this chronic complication. While ARDS appears to be the main cause of pulmonary fibrosis in COVID-19, the pathogenesis of ARDS caused by SARS-CoV-2 is different from the typical ARDS. Some therapies may be considered for reducing the fibrosis process in lung after COVI-19 infection namely pirfenidone, nintedanib and mesenchymal stem cells. Many patients are still recovering spontaneously in the first six weeks after acute COVID-19 infection and do not generally require fast-track entry into a pulmonary rehabilitation programme. However, those who have significantly persistent respiratory illness may need to be supported by pulmonary rehabilitation. Multidisciplinary intervention based on personalized evaluation and treatment which includes exercise training, education and behavioral modification can be given to improve the physical and psychological condition of patients with post-COVID pulmonary fibrosis. |
COVID-19; Indonesia; pulmonary fibrosis |
complication; hospital discharge; human; lung fibrosis; pandemic; virology; virus pneumonia; COVID-19; Humans; Pandemics; Patient Discharge; Pneumonia, Viral; Pulmonary Fibrosis; SARS-CoV-2 |
NLM (Medline) |
01259326 |
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34251340 |
Editorial |
Q3 |
321 |
14162 |
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450 |
Pujianto D., Oktarina M., Sharma Sharaswati I., Yulhasri Y. |
8745734300;57225172840;57225177505;57225180520; |
Hydrogen peroxide has adverse effects on human sperm quality parameters, induces apoptosis, and reduces survival |
2021 |
Journal of Human Reproductive Sciences |
14 |
2 |
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121 |
128 |
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1 |
https://www.scopus.com/inward/record.uri?eid=2-s2.0-85109421886&doi=10.4103%2fjhrs.jhrs_241_20&partnerID=40&md5=b51e205fbcc1300b22e8e8898e7a1c02 |
Department of Biology, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Master Program for Biomedical Sciences, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Department of Biochemistry and Molecular Biology, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia |
Pujianto, D., Department of Biology, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Oktarina, M., Master Program for Biomedical Sciences, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Sharma Sharaswati, I., Master Program for Biomedical Sciences, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Yulhasri, Y., Department of Biochemistry and Molecular Biology, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia |
Background: One of the causes of male fertility disorders is the exposure of oxidative stress on the human sperm. Understanding the mechanism of disturbance is important to develop a better treatment for infertile or subfertile patients. Aims: The aim of this study was to analyze the effects of hydrogen peroxide (H2O2) on human sperm quality parameters and cell survival. Settings and Design: This study used an experimental design. Materials and Methods: Sperm cells from 15 donors were washed in a Percoll gradient and dissolved in Biggers, Whitter, and Whittingham medium. Cells were incubated with H2O2at various concentrations from 0 to 250 μM for 2 h. Sperm viability was examined by eosin assay, sperm kinetic by computer-assisted sperm analyzer, sperm penetration by cervical mucus penetration assay, and membrane integrity by hypo-osmotic swelling test. Sperm capacitation, apoptosis, and cell survival were analyzed using western immunoblotting. Statistical Analysis Used: One-way ANOVA on SPSS 21 combined with post hoc LSD test was used to analyze differences among the groups. A P < 0.05 was considered significant. Results: Sperm viability and kinetic were significantly reduced at H2O2concentrations of 200 and 250 μM. H2O2reduced sperm capability to penetrate cervical mucus and also damage cell membrane integrity at all concentrations used. H2O2significantly inhibited sperm capacitation, indicated by reduced total tyrosine phosphorylation. H2O2exposure stimulated activation of caspase 3 and significantly reduced phosphorylated AKT at all concentrations used. Conclusions: H2O2comprehensively inhibits sperm qualities related to the capacity to fertilize oocyte, stimulates caspase activity, and inhibits cell survival. © 2021 Wolters Kluwer Medknow Publications. All rights reserved. |
AKT; capacitation; caspase; hydrogen peroxide; sperm |
caspase 3; hydrogen peroxide; malonaldehyde; protein kinase B; adverse event; analysis of variance; apoptosis; Article; cell survival; clinical article; densitometry; human; human cell; immunoblotting; kinetics; lipid peroxidation; male; male infertility; oxidative stress; post hoc analysis; protein phosphorylation; sperm capacitation; sperm preparation; sperm quality; sperm viability; spermatozoon penetration; uterine cervix mucus |
Wolters Kluwer Medknow Publications |
09741208 |
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Article |
Q3 |
484 |
10359 |
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456 |
Bahtiar A., Setyowati H., Mahanani R., Wati A., Arsianti A., Fadilah F. |
35365874400;57223255498;57223266884;57223271215;36124567000;56966708600; |
Rhaponticin contained Rheum officinale root extract improved Postmenopause symptom of Ovariectomized Rat |
2021 |
Journal of Advanced Pharmaceutical Technology and Research |
12 |
2 |
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175 |
179 |
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https://www.scopus.com/inward/record.uri?eid=2-s2.0-85105384592&doi=10.4103%2fjaptr.JAPTR_324_20&partnerID=40&md5=1f1fbda205bf337ab7c1628298d5d1ba |
Department of Pharmacology and Toxicology, Faculty of Pharmacy, Universitas Indonesia, Kampus UI, Depok, 16424, Indonesia; Department of Medicinal Chemistry, Faculty of Medicine, Universitas Indonesia, Kampus UI Jl, Salemba Raya, Jakarta, Indonesia |
Bahtiar, A., Department of Pharmacology and Toxicology, Faculty of Pharmacy, Universitas Indonesia, Kampus UI, Depok, 16424, Indonesia; Setyowati, H., Department of Pharmacology and Toxicology, Faculty of Pharmacy, Universitas Indonesia, Kampus UI, Depok, 16424, Indonesia; Mahanani, R., Department of Pharmacology and Toxicology, Faculty of Pharmacy, Universitas Indonesia, Kampus UI, Depok, 16424, Indonesia; Wati, A., Department of Pharmacology and Toxicology, Faculty of Pharmacy, Universitas Indonesia, Kampus UI, Depok, 16424, Indonesia; Arsianti, A., Department of Medicinal Chemistry, Faculty of Medicine, Universitas Indonesia, Kampus UI Jl, Salemba Raya, Jakarta, Indonesia; Fadilah, F., Department of Medicinal Chemistry, Faculty of Medicine, Universitas Indonesia, Kampus UI Jl, Salemba Raya, Jakarta, Indonesia |
Postmenopausal women have decreased levels of the hormone estrogen. Reduced estrogen levels will often involve many symptoms that reduced quality of life. This research aims to analyze the effects of Rheum officinale root extract on postmenopausal model rats. To this end, thirty rats underwent ovariectomy (OVX) surgery and six rats were operated without having their ovaries removed. The OVX was confirmed by body weight-uterus weight ratio and a vaginal swab. Six groups of the rats were performed: SHAM group and negative control groups are given vehicle; the positive control was assigned tamoxifen; and the extract has been given three doses 7, 35, and 175 mg/200 g BW, respectively, for 30 days. The calcium content of bone ash was measured using atomic absorption spectrophotometer. Blood pressure was evaluated using CODA®, and the metabolites in the blood were assessed using gas chromatography-mass spectrometry (MS) and high-performance liquid chromatography. As a result, using ultra-performance liquid chromatography (UPLC)-MS, we found that the extract's major component was rhaponticin and its metabolites. The bone calcium levels increased with increasing doses of the extract. In the OVX group, the bone calcium content was decreased significantly 51.56% ± 8.9% g compared with the SHAM group 62.97% ±5.6% g, and the administration of Rheum extract could restore the calcium content of the bone to become 69.27% ± 3.8% g. From the above data, we concluded that Rheum root extracts contain astrigin, rhaponticin, rhapontigenin, and desoxyrhaponticin. Rheum root extract could improve calcium content and lipid profiles of OVX rats by stimulation osteoblastogenesis. Rheum root extracts could control the blood pressure of OVX rats by reducing lipid profiles. © 2021 Wolters Kluwer Medknow Publications. All rights reserved. |
Calcium; hypertension; Kalembak; lipid profiles; osteoporosis; postmenopausal; rhaponticin; Rheum officinale |
antihypertensive agent; astringin; calcium; cholesterol; desoxyrhaponticin; high density lipoprotein; low density lipoprotein; rhapontigenin; rhapontin; Rheum officinale extract; tamoxifen; triacylglycerol; unclassified drug; analytical parameters; animal experiment; animal model; animal tissue; antihypertensive activity; Article; atomic absorption spectrometry; blood pressure measurement; body weight; body weight gain; body weight uterus weight ratio; bone density; calcium bone level; comparative study; controlled study; diastolic blood pressure; drug effect; female; high performance liquid chromatography; hypertension; Indonesia; lipid fingerprinting; mass fragmentography; nonhuman; ovariectomy; plant root; postmenopause; priority journal; protein analysis; rat; rat model; retention time |
Wolters Kluwer Medknow Publications |
01105558 |
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Article |
Q3 |
325 |
14045 |
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460 |
Darmaputra D.C., Zaman F.Y., Khu Y.L., Nagalingam V., Liew D., Aung A.K. |
57223041347;57208759841;57208757691;57215386437;7003970080;55117996600; |
Cost-analysis of opportunistic influenza vaccination in general medical inpatients |
2021 |
Internal Medicine Journal |
51 |
4 |
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591 |
595 |
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https://www.scopus.com/inward/record.uri?eid=2-s2.0-85104572736&doi=10.1111%2fimj.15270&partnerID=40&md5=6be726bbda46f6b4342a09dd962a3b11 |
Faculty of Medicine, University of Indonesia, Jakarta, Indonesia; School of Public Health and Preventive Medicine, Monash University, Melbourne, VIC, Australia; Department of General Medicine, The Alfred Hospital, Melbourne, VIC, Australia |
Darmaputra, D.C., Faculty of Medicine, University of Indonesia, Jakarta, Indonesia, School of Public Health and Preventive Medicine, Monash University, Melbourne, VIC, Australia; Zaman, F.Y., Department of General Medicine, The Alfred Hospital, Melbourne, VIC, Australia; Khu, Y.L., Department of General Medicine, The Alfred Hospital, Melbourne, VIC, Australia; Nagalingam, V., Department of General Medicine, The Alfred Hospital, Melbourne, VIC, Australia; Liew, D., School of Public Health and Preventive Medicine, Monash University, Melbourne, VIC, Australia, Department of General Medicine, The Alfred Hospital, Melbourne, VIC, Australia; Aung, A.K., School of Public Health and Preventive Medicine, Monash University, Melbourne, VIC, Australia, Department of General Medicine, The Alfred Hospital, Melbourne, VIC, Australia |
Influenza vaccination is an important preventative health measure in the elderly and those with medical comorbidities. It has been shown to reduce hospitalisations, cardiovascular and respiratory complications. A significant proportion of patients admitted to general medicine are eligible for opportunistic inpatient influenza vaccination. This study explores the cost-effectiveness of such a strategy in reducing subsequent healthcare utilisation costs. © 2021 Royal Australasian College of Physicians |
cost-analysis; elderly; influenza; inpatient; vaccination |
aged; article; cost effectiveness analysis; health care utilization; hospital patient; human; influenza vaccination; cost benefit analysis; hospital patient; hospitalization; influenza; vaccination; influenza vaccine; Aged; Cost-Benefit Analysis; Hospitalization; Humans; Influenza Vaccines; Influenza, Human; Inpatients; Vaccination |
Blackwell Publishing |
14440903 |
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33890379 |
Article |
Q3 |
596 |
8475 |
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472 |
Kurniawan A., Wijaya T., Hutami W.D. |
57204398223;57222656233;57219938996; |
Spontaneous healing of a traumatic critical radius bone defect in adolescent: A rare case report |
2021 |
International Journal of Surgery Case Reports |
81 |
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105806 |
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https://www.scopus.com/inward/record.uri?eid=2-s2.0-85103668624&doi=10.1016%2fj.ijscr.2021.105806&partnerID=40&md5=4c70b264f853582354fc36b39f9dc680 |
Department of Orthopaedics and Traumatology, Cipto Mangunkusumo National Central Hospital and Faculty of Medicine, Universitas Indonesia, Jalan Diponegoro No. 71, Jakarta Pusat, Jakarta, 10430, Indonesia |
Kurniawan, A., Department of Orthopaedics and Traumatology, Cipto Mangunkusumo National Central Hospital and Faculty of Medicine, Universitas Indonesia, Jalan Diponegoro No. 71, Jakarta Pusat, Jakarta, 10430, Indonesia; Wijaya, T., Department of Orthopaedics and Traumatology, Cipto Mangunkusumo National Central Hospital and Faculty of Medicine, Universitas Indonesia, Jalan Diponegoro No. 71, Jakarta Pusat, Jakarta, 10430, Indonesia; Hutami, W.D., Department of Orthopaedics and Traumatology, Cipto Mangunkusumo National Central Hospital and Faculty of Medicine, Universitas Indonesia, Jalan Diponegoro No. 71, Jakarta Pusat, Jakarta, 10430, Indonesia |
Introduction and importance: Fracture with a critical bone loss is associated with a profound burden of disease impact. Although there are several options exist for its treatment, but still those reconstructive procedures are technically demanding, relatively expensive and sometimes the result is less than what was expected. The objective of this study is to report a rare case of spontaneous healing of a critical radial bone defect in an adolescent. Case presentation: We reported a 15 year old boy with a segmental open fracture of left radius, open fracture of left distal shaft ulna and closed fracture of left intercondylar humerus. The middle fragment of a fractured radius was extruded out, pulled out and then thrown away by his parent. Debridement, open reduction, and internal fixation for ulna were performed as well as reposition and internal fixation for the intercondylar humerus fracture. The plan was to wait until the ulnar fracture and intercondylar fracture to heal without any sign of infection and proceed to overcome the radial critical bone defect. This case report had been reported in line with SCARE criteria. The patient showed up seven months later with solid union of the critical radius bone defect and fully functioning hand with only slight limitation in pronation. Clinical discussion: Osteogenesis in fracture requires osteogenic cells, osteoinductive components, osteoconductive scaffold, and stability. Despite the fact that critical bone defect poses great challenge for its management, intact periosteum and sufficient soft tissue perfusion were able to provide those biologic requirements adequately for fracture healing and ensure spontaneous healing of a traumatic critical bone loss in adolescent without any reconstructive procedure. Conclusion: Spontaneous healing in critical bone defect is possible, provided all the favorable factors present to support this phenomenon. © 2021 The Authors |
Adolescent bone defect; Case report; Critical bone defect; Rare case; Spontaneous healing |
antibiotic agent; adolescent; arm swelling; Article; bone defect; case report; clinical article; debridement; distal humerus; distal radius; elbow; emergency care; falling; follow up; forearm; fracture healing; hand function; hospital admission; human; humerus fracture; male; medical history; metaphysis; open fracture; open fracture reduction; osteolysis; osteosynthesis; outcome assessment; outpatient department; periosteum; physical examination; priority journal; pronation; radial critical bone defect; radius fracture; radius shaft fracture; range of motion; reconstructive surgery; soft tissue; treatment planning; tree; ulna fracture; wound care; wound healing |
Elsevier Ltd |
22102612 |
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Article |
Q3 |
232 |
17549 |
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473 |
Latief W., Enggra N. |
57210959510;57222656758; |
Spiral oblique retinacular ligament reconstruction using lateral band technique to treat swan neck deformity due to chronic mallet finger: A case report |
2021 |
International Journal of Surgery Case Reports |
81 |
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105811 |
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https://www.scopus.com/inward/record.uri?eid=2-s2.0-85103658803&doi=10.1016%2fj.ijscr.2021.105811&partnerID=40&md5=ae6327366a0890dab1d668217845c18e |
Department of Orthopaedics and Traumatology, Faculty of Medicine, Universitas Indonesia-Cipto Mangunkusumo Hospital, Jakarta, Indonesia |
Latief, W., Department of Orthopaedics and Traumatology, Faculty of Medicine, Universitas Indonesia-Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Enggra, N., Department of Orthopaedics and Traumatology, Faculty of Medicine, Universitas Indonesia-Cipto Mangunkusumo Hospital, Jakarta, Indonesia |
Introduction: Swan neck deformity (SND) is characterized by hyperextension of proximal interphalangeal (PIP) joint and extension lag of distal interphalangeal (DIP) joint with functional loss of finger and impairs of tight grip of the finger. SND often results from chronic mallet injury and requires surgical treatment. One of the procedure is spiral oblique retinaculum ligament (SORL) reconstruction. We reported good outcome of swan neck deformity due to chronic mallet finger cases treated with SORL reconstruction using lateral band technique. Case presentation: We presented 2 case of swan neck deformity due to chronic mallet finger. A 21-year-old male with deformity of the left index finger for 2 years with with extension lag 50° and −20° PIP joint hyperextension and A 18-year-female with deformity of right ring finger for 4 years with extension lag 40° and −20° PIP joint hyperextension. We performed SORL reconstruction using lateral band technique. Ten weeks after surgery, patient achieved good range of motion and stability of PIP and DIP joint was obtained. Discussion: SORL reconstruction in a finger with a chronic mallet deformity coordinates extension of PIP and DIP joints by a dynamic tenodesis effect. This concept improves stability of both DIP and PIP joints by linking the volar flexor sheath to the lateral aspect of the terminal tendon using lateral band, thereby providing a mechanism of for automatic DIP joint extension upon active PIP extension. Conclusion: SORL reconstruction using lateral band technique may be a good choice for treating swan neck deformity. © 2021 |
Chronic mallet finger; Lateral band; SORL; Swan neck deformity |
adult; Article; case report; chronic mallet injury; clinical article; female; finger injury; finger malformation; follow up; high school student; human; index finger; interphalangeal joint; lateral band technique; ligament surgery; male; outcome assessment; passive movement; physical examination; priority journal; range of motion; right handedness; ring finger; spiral oblique retinacular ligament reconstruction; surgical technique; swan neck deformity; young adult |
Elsevier Ltd |
22102612 |
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Article |
Q3 |
232 |
17549 |
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474 |
Yulian E.D., Pandelaki J., Kodrat E., Wibisana I.G.N.G. |
55983956600;35759266900;57191430080;57219660008; |
Forequarter amputation post transarterial chemoembolization and radiation in synovial sarcoma: A case report |
2021 |
International Journal of Surgery Case Reports |
81 |
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105824 |
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https://www.scopus.com/inward/record.uri?eid=2-s2.0-85103395086&doi=10.1016%2fj.ijscr.2021.105824&partnerID=40&md5=5ca80e2a67c402ef91b604a618b712a1 |
Surgical Oncology Division, Department of Surgery, Dr. Cipto Mangunkusumo General Hospital, Faculty of Medicine Universitas Indonesia, Indonesia; Interventional Radiology Division, Department of Radiology, Dr. Cipto Mangunkusumo General Hospital, Faculty of Medicine Universitas Indonesia, Indonesia; Department of Anatomical Pathology, Dr. Cipto Mangunkusumo General Hospital, Faculty of Medicine Universitas Indonesia, Indonesia |
Yulian, E.D., Surgical Oncology Division, Department of Surgery, Dr. Cipto Mangunkusumo General Hospital, Faculty of Medicine Universitas Indonesia, Indonesia; Pandelaki, J., Interventional Radiology Division, Department of Radiology, Dr. Cipto Mangunkusumo General Hospital, Faculty of Medicine Universitas Indonesia, Indonesia; Kodrat, E., Department of Anatomical Pathology, Dr. Cipto Mangunkusumo General Hospital, Faculty of Medicine Universitas Indonesia, Indonesia; Wibisana, I.G.N.G., Surgical Oncology Division, Department of Surgery, Dr. Cipto Mangunkusumo General Hospital, Faculty of Medicine Universitas Indonesia, Indonesia |
Introduction and importance: Forequarter amputation or interscapulathoracalis amputation is a major amputation procedure that involves the entire upper extremity, scapula, and a whole or part of the clavicula. Forequarter amputation is commonly used to control bleeding in malignant tumor cases in which no treatment is available for the extremities. Case presentation: We report a case of forequarter amputation in a 25-year-old patient with synovial sarcoma. Transarterial chemoembolization (TACE) and radiation synovial sarcoma were performed in the patient to reduce bleeding. This technique may also be used for treating synovial sarcoma with massive bleeding. Clinical discussion: Despite forequarter amputation indications in malignant tumor cases and recurrent cancer cases, the effectiveness of this technique remains unclear. The patient was readmitted with a recurrent mass three months after surgery. Conclusion: In this study, TACE and radiotherapy are effective in controlling bleeding preoperatively and intraoperatively in patients with synovial sarcoma. © 2021 The Authors |
Case report; Forequarter amputation; Radiation; Synovial sarcoma; Transarterial chemoembolization |
corticosteroid; doxorubicin; epithelial membrane antigen; gelfoam; iodinated poppyseed oil; polyvinyl alcohol; povidone iodine; protein S 100; sulfadiazine silver; adult; arm amputation; Article; axillary artery; bleeding; blood transfusion; cancer patient; cancer radiotherapy; cancer surgery; case report; cauterization; chemoembolization; chronic pain; clinical article; clinical feature; corticosteroid therapy; device removal; digital subtraction angiography; fibromyxosarcoma; forequarter amputation; histopathology; human; human tissue; immunohistochemistry; lymphedema; nuclear magnetic resonance imaging; pectoralis major muscle; postoperative hemorrhage; primary tumor; priority journal; right subclavian artery; shoulder girdle; spindle cell sarcoma; synovial sarcoma; tumor volume; young |
Elsevier Ltd |
22102612 |
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Article |
Q3 |
232 |
17549 |
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