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457 |
Rozaliyani A., Setianingrum F., Azahra S., Abdullah A., Fatril A.E., Rosianawati H., Burhan E., Handayani D., Arifin A.R., Zaini J., Tugiran M., Adawiyah R., Syam R., Wibowo H., Wahyuningsih R., Kosmidis C., Denning D.W. |
57203065912;57203061705;57219977463;57223138415;57223130315;57220203100;36058554600;57219413838;57223139966;57221833355;57218291154;57208658742;57218290535;57217690943;6507268400;16834840500;57223404509; |
Performance of ldbio aspergillus wb and ict antibody detection in chronic pulmonary aspergillosis |
2021 |
Journal of Fungi |
7 |
4 |
311 |
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https://www.scopus.com/inward/record.uri?eid=2-s2.0-85105015900&doi=10.3390%2fjof7040311&partnerID=40&md5=d403a899e390ae45f6c1071eeb2d4832 |
Department of Parasitology, Faculty of Medicine, Universitas Indonesia, Jakarta, 10430, Indonesia; Pulmonary Mycosis Centre, Jakarta, 10430, Indonesia; Faculty of Medicine, Universitas Indonesia, Jakarta, 10430, Indonesia; Department of Pulmonology and Respiratory Medicine, Faculty of Medicine, Universitas Indonesia, Persahabatan National Respiratory Referral Hospital, Jakarta, 13230, Indonesia; MH Thamrin Hospital, Jakarta, 10440, Indonesia; Department of Parasitology, Faculty of Medicine, Universitas Kristen, Jakarta, 13530, Indonesia; Manchester Academic Health Science Centre, Division of Infection, Immunity and Respiratory Medicine, Faculty of Biology, School of Biological Sciences, Medicine and Health, University of Manchester, Manchester, M23 9LT, United Kingdom |
Rozaliyani, A., Department of Parasitology, Faculty of Medicine, Universitas Indonesia, Jakarta, 10430, Indonesia, Pulmonary Mycosis Centre, Jakarta, 10430, Indonesia; Setianingrum, F., Department of Parasitology, Faculty of Medicine, Universitas Indonesia, Jakarta, 10430, Indonesia, Pulmonary Mycosis Centre, Jakarta, 10430, Indonesia; Azahra, S., Faculty of Medicine, Universitas Indonesia, Jakarta, 10430, Indonesia; Abdullah, A., Department of Parasitology, Faculty of Medicine, Universitas Indonesia, Jakarta, 10430, Indonesia; Fatril, A.E., Department of Parasitology, Faculty of Medicine, Universitas Indonesia, Jakarta, 10430, Indonesia; Rosianawati, H., Department of Pulmonology and Respiratory Medicine, Faculty of Medicine, Universitas Indonesia, Persahabatan National Respiratory Referral Hospital, Jakarta, 13230, Indonesia; Burhan, E., Pulmonary Mycosis Centre, Jakarta, 10430, Indonesia, Department of Pulmonology and Respiratory Medicine, Faculty of Medicine, Universitas Indonesia, Persahabatan National Respiratory Referral Hospital, Jakarta, 13230, Indonesia; Handayani, D., Pulmonary Mycosis Centre, Jakarta, 10430, Indonesia, Department of Pulmonology and Respiratory Medicine, Faculty of Medicine, Universitas Indonesia, Persahabatan National Respiratory Referral Hospital, Jakarta, 13230, Indonesia; Arifin, A.R., Pulmonary Mycosis Centre, Jakarta, 10430, Indonesia, MH Thamrin Hospital, Jakarta, 10440, Indonesia; Zaini, J., Pulmonary Mycosis Centre, Jakarta, 10430, Indonesia, Department of Pulmonology and Respiratory Medicine, Faculty of Medicine, Universitas Indonesia, Persahabatan National Respiratory Referral Hospital, Jakarta, 13230, Indonesia; Tugiran, M., Department of Parasitology, Faculty of Medicine, Universitas Indonesia, Jakarta, 10430, Indonesia, Pulmonary Mycosis Centre, Jakarta, 10430, Indonesia; Adawiyah, R., Department of Parasitology, Faculty of Medicine, Universitas Indonesia, Jakarta, 10430, Indonesia, Pulmonary Mycosis Centre, Jakarta, 10430, Indonesia; Syam, R., Department of Parasitology, Faculty of Medicine, Universitas Indonesia, Jakarta, 10430, Indonesia, Pulmonary Mycosis Centre, Jakarta, 10430, Indonesia; Wibowo, H., Department of Parasitology, Faculty of Medicine, Universitas Indonesia, Jakarta, 10430, Indonesia, Pulmonary Mycosis Centre, Jakarta, 10430, Indonesia; Wahyuningsih, R., Department of Parasitology, Faculty of Medicine, Universitas Indonesia, Jakarta, 10430, Indonesia, Pulmonary Mycosis Centre, Jakarta, 10430, Indonesia, Department of Parasitology, Faculty of Medicine, Universitas Kristen, Jakarta, 13530, Indonesia; Kosmidis, C., Manchester Academic Health Science Centre, Division of Infection, Immunity and Respiratory Medicine, Faculty of Biology, School of Biological Sciences, Medicine and Health, University of Manchester, Manchester, M23 9LT, United Kingdom; Denning, D.W., Manchester Academic Health Science Centre, Division of Infection, Immunity and Respiratory Medicine, Faculty of Biology, School of Biological Sciences, Medicine and Health, University of Manchester, Manchester, M23 9LT, United Kingdom |
The detection of Aspergillus antibody has a key role in the diagnosis of chronic pulmonary as-pergillosis. Western blot (WB) and immunochromatography (ICT) lateral flow detection of Aspergillus antibody can be used as confirmatory and screening assays but their comparative performance in TB patients is not known. This study investigated the performance of these assays among 88 post-tuberculosis patients with suspected CPA. Sensitivity, specificity, receiver operating curve (ROC), area under-curve (AUC) and the agreement between two assays were evaluated. Both WB and ICT showed good sensitivity (80% and 85%, respectively) for detection of Aspergillus antibodies. Substantial agreement (0.716) between these assays was also obtained. The highest AUC result (0.804) was achieved with the combination of WB and ICT. The global intensity of WB correlated with the severity of symptoms in CPA group (p = 0.001). The combination of WB and ICT may increase specificity in CPA diagnosis. © 2021 by the authors. Licensee MDPI, Basel, Switzerland. |
Chronic pulmonary aspergillosis; Immunochromatography; Western blot |
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MDPI AG |
2309608X |
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Article |
Q1 |
1702 |
1800 |
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112 |
Ong J., Ong A.M.L., Ong S., Xin X., Lee Y.Y., Pausawasdi N., De Lusong M.A., Makmun D., Chong V.H., Ho S.H., Lim W., Ong D., Dan Y.Y., Khor C. |
57193716100;36942342000;35741447900;57326122500;56191149300;6602327609;23767987600;16638046900;54790563600;50561284200;57194415809;56013316700;8699022400;8549610200; |
The impact of the coronavirus disease 2019 pandemic on gastroenterologists in Southeast Asia: A mixed-methods study |
2021 |
Journal of Gastroenterology and Hepatology (Australia) |
36 |
11 |
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3056 |
3068 |
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1 |
https://www.scopus.com/inward/record.uri?eid=2-s2.0-85112680822&doi=10.1111%2fjgh.15594&partnerID=40&md5=3c1bb0505aa3a502aa7cea4abadd518a |
Department of Medicine, National University of Singapore, Singapore; Department of Engineering, University of Cambridge, Cambridge, United Kingdom; Department of Gastroenterology and Hepatology, Singapore General Hospital, Singapore; Duke-NUS Medical School, Singapore; Department of Surgical Intensive Care, Singapore General Hospital, Singapore; Department of Anaesthesiology, Sengkang General Hospital, Singapore; Health Services Research Unit, Singapore General Hospital, Singapore; School of Medical Sciences, Universiti Sains Malaysia, Kota Bharu, Malaysia; GI Function and Motility Unit, Hospital Universiti Sains Malaysia, Kota Bharu, Malaysia; Division of Gastroenterology, Department of Medicine, Mahidol University Faculty of Medicine at Siriraj Hospital, Bangkok, Thailand; Section of Advanced Endoscopy, Division of Gastroenterology, Department of Medicine, Philippine General Hospital, Manila, Philippines; Faculty of Medicine, Division of Gastroenterology, Department of Internal Medicine, Cipto Mangunkusumo National General Hospital, Universitas Indonesia, Jakarta, Indonesia; Gastroenterology Unit, Department of Medicine, RIPAS Hospital, Bandar Seri Begawan, Brunei Darussalam; Institute of Health Sciences, PAPRSB Universiti of Brunei Darussalam, Bandar Seri Begawan, Brunei Darussalam; Department of Medicine, University of Malaya, Kuala Lumpur, Malaysia; Department of Anaesthesiology, Singapore General Hospital, Singapore; Department of Medicine, Division of Gastroenterology and Hepatology, National University Hospital, Singapore |
Ong, J., Department of Medicine, National University of Singapore, Singapore, Department of Engineering, University of Cambridge, Cambridge, United Kingdom; Ong, A.M.L., Department of Gastroenterology and Hepatology, Singapore General Hospital, Singapore, Duke-NUS Medical School, Singapore; Ong, S., Department of Surgical Intensive Care, Singapore General Hospital, Singapore, Department of Anaesthesiology, Sengkang General Hospital, Singapore; Xin, X., Health Services Research Unit, Singapore General Hospital, Singapore; Lee, Y.Y., School of Medical Sciences, Universiti Sains Malaysia, Kota Bharu, Malaysia, GI Function and Motility Unit, Hospital Universiti Sains Malaysia, Kota Bharu, Malaysia; Pausawasdi, N., Division of Gastroenterology, Department of Medicine, Mahidol University Faculty of Medicine at Siriraj Hospital, Bangkok, Thailand; De Lusong, M.A., Section of Advanced Endoscopy, Division of Gastroenterology, Department of Medicine, Philippine General Hospital, Manila, Philippines; Makmun, D., Faculty of Medicine, Division of Gastroenterology, Department of Internal Medicine, Cipto Mangunkusumo National General Hospital, Universitas Indonesia, Jakarta, Indonesia; Chong, V.H., Gastroenterology Unit, Department of Medicine, RIPAS Hospital, Bandar Seri Begawan, Brunei Darussalam, Institute of Health Sciences, PAPRSB Universiti of Brunei Darussalam, Bandar Seri Begawan, Brunei Darussalam; Ho, S.H., Department of Medicine, University of Malaya, Kuala Lumpur, Malaysia; Lim, W., Department of Anaesthesiology, Sengkang General Hospital, Singapore, Department of Anaesthesiology, Singapore General Hospital, Singapore; Ong, D., Department of Medicine, Division of Gastroenterology and Hepatology, National University Hospital, Singapore; Dan, Y.Y., Department of Medicine, National University of Singapore, Singapore, Department of Medicine, Division of Gastroenterology and Hepatology, National University Hospital, Singapore; Khor, C., Department of Gastroenterology and Hepatology, Singapore General Hospital, Singapore, Duke-NUS Medical School, Singapore |
Background and Aim: The coronavirus disease 2019 pandemic has impacted gastroenterology practices worldwide; however, its protracted effects within Southeast Asia were unknown. The primary aim of the study was to determine the impact of the pandemic on clinical demands including burnout among gastroenterologists within the region. The secondary aim was to identify risk factors for burnout and determine regional stressors. Methods: This was a mixed-methods study. Gastroenterologists were surveyed electronically between September 1 and December 7, 2020, via gastroenterology and endoscopy societies of Brunei, Indonesia, Malaysia, Philippines, Singapore, and Thailand. Quantitative and qualitative data were collected. The 22-item Maslach Burnout Inventory-Human Services Survey (MBI-HSS) was used to detect burnout. Quantitative data were non-parametric; non-parametric methods were used for statistical comparisons. Logistic regression was used to determine risk factors for burnout. Content analysis method was used to analyze qualitative data. Ethical approval was obtained. Results: A total of 73.0% reported that they were still significantly affected by the pandemic. Of these, 40.5% reported increased workload and 59.5% decreased workload. Statistically significant differences in weekly working hours, endoscopy, and inpatient volumes were present. No differences were observed in outpatient volumes, likely because of telemedicine. Burnout was common; however, 50.1% of gastroenterologists were unaware of or did not have access to mental health support. This, as well as depression, being a trainee, and public sector work, increased burnout risk significantly. Conclusion: The effects of the pandemic are multifaceted, and burnout is common among Southeast Asian gastroenterologists. Safeguards for mental health are suboptimal, and improvements are urgently needed. © 2021 The Authors. Journal of Gastroenterology and Hepatology published by Journal of Gastroenterology and Hepatology Foundation and John Wiley & Sons Australia, Ltd. |
burnout; COVID-19; gastroenterologists; gastroenterology; pandemic |
adult; Article; Brunei Darussalam; content analysis; controlled study; coronavirus disease 2019; data collection method; depression; endoscopy; female; gastroenterologist; hospital patient; human; Indonesia; job stress; logistic regression analysis; major clinical study; Malaysia; male; Maslach Burnout Inventory-Human Services Survey; mental health; multicenter study; nonparametric test; pandemic; Philippines; professional burnout; public sector; qualitative research; quantitative analysis; risk factor; Singapore; Southeast Asia; telemedicine; Thailand; workload; burnout; epidemiology; gastroenterologist; middle aged; pandemic; psychology; questionnaire; Adult; Asia, Southeastern; Burnout, Professional; COVID-19; Female; Gastroenterologists; Humans; Male; Middle Aged; Pandemics; SARS-CoV-2 |
John Wiley and Sons Inc |
08159319 |
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34159640 |
Article |
Q1 |
1214 |
3242 |
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266 |
Akada J., Tshibangu-Kabamba E., Tuan V.P., Kurogi S., Matsuo Y., Ansari S., Doohan D., Phuc B.H., Subsomwong P., Waskito L.A., Binh T.T., Nguyen L.T., Khien V.V., Dung H.D.Q., Miftahussurur M., Syam A.F., Tshering L., Vilaichone R.-K., Mahachai V., Ratanachu-ek T., Shrestha P.K., Yee T.T., Htet K., Aftab H., Matsuhisa T., Uchida T., Okimoto T., Mizukami K., Kodama M., Murakami K., Takahashi N., Yamaoka Y. |
6506986959;57218760439;57195367045;57195277760;55567953900;55523204000;57204644036;57222165127;57113712700;57192177367;55415987700;35285702000;6507745643;56681908900;56323903000;8443384400;57211294242;6701788898;7003739875;6507122700;8099897200;57211455497;57241639000;55359226800;7005493709;35286123100;7005300232;7005239531;35285903900;57214336895;7403938865;55183784100; |
Serum Helicobacter pylori antibody reactivity in seven Asian countries using an automated latex aggregation turbidity assay |
2021 |
Journal of Gastroenterology and Hepatology (Australia) |
36 |
8 |
|
2198 |
2209 |
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2 |
https://www.scopus.com/inward/record.uri?eid=2-s2.0-85102320750&doi=10.1111%2fjgh.15467&partnerID=40&md5=71760e350adacfbf3a65094e953e8182 |
Department of Environmental and Preventive Medicine, Faculty of Medicine, Oita University, Yufu, Japan; Clinical Laboratory Center, Oita University Hospital, Yufu, Japan; Department of Endoscopy, Cho Ray Hospital, Ho Chi Minh City, Viet Nam; Department of Hepatogastroenterology, 108 Military Central Hospital, Hanoi, Viet Nam; Institute of Tropical Disease, Airlangga University, Surabaya, Indonesia; Gastroentero-Hepatology Division, Department of Internal Medicine, Faculty of Medicine-Dr. Soetomo Teaching Hospital, Airlangga University, Surabaya, Indonesia; Division of Gastroenterology, Department of Intestinal Medicine, Faculty of Medicine, University of Indonesia, Jakarta, Indonesia; Department of Surgery, Jigme Dorji Wangchuck National Referral Hospital, Thimphu, Bhutan; Gastroenterology Unit, Digestive Diseases Research Center, Thammasat University Hospital, Khlong Luang, Thailand; Department of Medicine, Chulabhorn International College of Medicine, Thammasat University Hospital, Khlong Luang, Thailand; GI and Liver Center, Bangkok Medical Center, Bangkok, Thailand; Department of Surgery, Rajavithi Hospital, Bangkok, Thailand; Department of Gastroenterology, Maharajgunj Medical Campus, Tribhuvan University Teaching Hospital, Kathmandu, Nepal; Department of GI and HBP Surgery, No (2) Defense Service General Hospital, Nay Pyi Taw, Myanmar; Department of GI and HBP Surgery, No (1) Defense Service General Hospital, Mingaladon, Myanmar; Department of Gastroenterology, Dhaka Medical Collage and Hospital, Dhaka, Bangladesh; Department of Gastroenterology, Tama-Nagayama University Hospital, Nippon Medical School, Tama, Japan; Department of Molecular Pathology, Faculty of Medicine, Oita University, Yufu, Japan; Department of Gastroenterology, Faculty of Medicine, Oita University, Yufu, Japan; Faculty of Welfare and Health Science, Oita University, Yufu, Japan; Global Oita Medical Advanced Research Center for Health, Oita University, Yufu, Japan; Department of Medicine, Gastroenterology and Hepatology Section, Baylor College of Medicine, Houston, TX, United States |
Akada, J., Department of Environmental and Preventive Medicine, Faculty of Medicine, Oita University, Yufu, Japan; Tshibangu-Kabamba, E., Department of Environmental and Preventive Medicine, Faculty of Medicine, Oita University, Yufu, Japan; Tuan, V.P., Department of Environmental and Preventive Medicine, Faculty of Medicine, Oita University, Yufu, Japan, Department of Endoscopy, Cho Ray Hospital, Ho Chi Minh City, Viet Nam; Kurogi, S., Clinical Laboratory Center, Oita University Hospital, Yufu, Japan, Department of Molecular Pathology, Faculty of Medicine, Oita University, Yufu, Japan; Matsuo, Y., Department of Environmental and Preventive Medicine, Faculty of Medicine, Oita University, Yufu, Japan; Ansari, S., Department of Environmental and Preventive Medicine, Faculty of Medicine, Oita University, Yufu, Japan; Doohan, D., Department of Environmental and Preventive Medicine, Faculty of Medicine, Oita University, Yufu, Japan, Institute of Tropical Disease, Airlangga University, Surabaya, Indonesia; Phuc, B.H., Department of Environmental and Preventive Medicine, Faculty of Medicine, Oita University, Yufu, Japan; Subsomwong, P., Department of Environmental and Preventive Medicine, Faculty of Medicine, Oita University, Yufu, Japan; Waskito, L.A., Department of Environmental and Preventive Medicine, Faculty of Medicine, Oita University, Yufu, Japan, Institute of Tropical Disease, Airlangga University, Surabaya, Indonesia; Binh, T.T., Department of Endoscopy, Cho Ray Hospital, Ho Chi Minh City, Viet Nam; Nguyen, L.T., Department of Hepatogastroenterology, 108 Military Central Hospital, Hanoi, Viet Nam; Khien, V.V., Department of Hepatogastroenterology, 108 Military Central Hospital, Hanoi, Viet Nam; Dung, H.D.Q., Department of Endoscopy, Cho Ray Hospital, Ho Chi Minh City, Viet Nam; Miftahussurur, M., Institute of Tropical Disease, Airlangga University, Surabaya, Indonesia, Gastroentero-Hepatology Division, Department of Internal Medicine, Faculty of Medicine-Dr. Soetomo Teaching Hospital, Airlangga University, Surabaya, Indonesia; Syam, A.F., Division of Gastroenterology, Department of Intestinal Medicine, Faculty of Medicine, University of Indonesia, Jakarta, Indonesia; Tshering, L., Department of Surgery, Jigme Dorji Wangchuck National Referral Hospital, Thimphu, Bhutan; Vilaichone, R.-K., Gastroenterology Unit, Digestive Diseases Research Center, Thammasat University Hospital, Khlong Luang, Thailand, Department of Medicine, Chulabhorn International College of Medicine, Thammasat University Hospital, Khlong Luang, Thailand; Mahachai, V., GI and Liver Center, Bangkok Medical Center, Bangkok, Thailand; Ratanachu-ek, T., Department of Surgery, Rajavithi Hospital, Bangkok, Thailand; Shrestha, P.K., Department of Gastroenterology, Maharajgunj Medical Campus, Tribhuvan University Teaching Hospital, Kathmandu, Nepal; Yee, T.T., Department of GI and HBP Surgery, No (2) Defense Service General Hospital, Nay Pyi Taw, Myanmar; Htet, K., Department of GI and HBP Surgery, No (1) Defense Service General Hospital, Mingaladon, Myanmar; Aftab, H., Department of Gastroenterology, Dhaka Medical Collage and Hospital, Dhaka, Bangladesh; Matsuhisa, T., Department of Gastroenterology, Tama-Nagayama University Hospital, Nippon Medical School, Tama, Japan; Uchida, T., Department of Molecular Pathology, Faculty of Medicine, Oita University, Yufu, Japan; Okimoto, T., Department of Gastroenterology, Faculty of Medicine, Oita University, Yufu, Japan; Mizukami, K., Department of Gastroenterology, Faculty of Medicine, Oita University, Yufu, Japan; Kodama, M., Department of Gastroenterology, Faculty of Medicine, Oita University, Yufu, Japan, Faculty of Welfare and Health Science, Oita University, Yufu, Japan; Murakami, K., Department of Gastroenterology, Faculty of Medicine, Oita University, Yufu, Japan; Takahashi, N., Clinical Laboratory Center, Oita University Hospital, Yufu, Japan; Yamaoka, Y., Department of Environmental and Preventive Medicine, Faculty of Medicine, Oita University, Yufu, Japan, Global Oita Medical Advanced Research Center for Health, Oita University, Yufu, Japan, Department of Medicine, Gastroenterology and Hepatology Section, Baylor College of Medicine, Houston, TX, United States |
Background and Aim: To determine the application range of diagnostic kits utilizing anti-Helicobacter pylori antibody, we tested a newly developed latex aggregation turbidity assay (latex) and a conventional enzyme-linked immunosorbent assay (E-plate), both containing Japanese H. pylori protein lysates as antigens, using sera from seven Asian countries. Methods: Serum samples (1797) were obtained, and standard H. pylori infection status and atrophy status were determined by culture and histology (immunohistochemistry) using gastric biopsy samples from the same individuals. The two tests (enzyme-linked immunosorbent assay and latex) were applied, and receiver operating characteristics analysis was performed. Results: Area under the curve (AUC) from the receiver operating characteristic of E-plate and latex curves were almost the same and the highest in Vietnam. The latex AUC was slightly lower than the E-plate AUC in other countries, and the difference became statistically significant in Myanmar and then Bangladesh as the lowest. To consider past infection cases, atrophy was additionally evaluated. Most of the AUCs decreased using this atrophy-evaluated status; however, the difference between the two kits was not significant in each country, but the latex AUC was better using all samples. Practical cut-off values were 3.0 U/mL in the E-test and 3.5 U/mL in the latex test, to avoid missing gastric cancer patients to the greatest extent possible. Conclusions: The kits were applicable in all countries, but new kits using regional H. pylori strains are recommended for Myanmar and Bangladesh. Use of a cut-off value lower than the best cut-off value is essential for screening gastric cancer patients. © 2021 Journal of Gastroenterology and Hepatology Foundation and John Wiley & Sons Australia, Ltd |
Asia; ELISA; Helicobacter pylori; Latex aggregation turbidity assay; Serum antibody |
antigen; bacterium antibody; immunoglobulin G; protein hydrolysate; bacterium antibody; adult; antibody blood level; Article; Asia; bacterial strain; bacterium culture; Bangladesh; Bhutan; cancer patient; cancer screening; controlled study; diagnostic accuracy; diagnostic test; evaluation study; female; Helicobacter infection; Helicobacter pylori; histopathology; human; human tissue; immunohistochemistry; Indonesia; infection rate; Japan; latex aggregation turbidity assay; major clinical study; male; marginal zone lymphoma; middle aged; Myanmar; Nepal; nonhuman; plate ELISA; predictive value; receiver operating characteristic; reference value; sensitivity and specificity; serum; statistical significance; stomach atrophy; stomach biopsy; stomach cancer; Viet Nam; aged; atrophy; biopsy; bloo |
John Wiley and Sons Inc |
08159319 |
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33609333 |
Article |
Q1 |
1214 |
3242 |
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267 |
Quek S.X.Z., Loo E.X.L., Demutska A., Chua C.E., Kew G.S., Wong S., Lau H.X., Low E.X.S., Loh T.L., Lung O.S., Hung E.C.W., Rahman M.M., Ghoshal U.C., Wong S.H., Cheung C.K.Y., Syam A.F., Tan N., Xiao Y., Liu J.-S., Lu F., Chen C.-L., Lee Y.Y., Maralit R.M., Kim Y.-S., Oshima T., Miwa H., Pang J., Siah K.T.H. |
57222222782;50162082500;36136970000;56816437200;56611839100;57222223736;57218857855;57201335892;57222224359;57222226377;7004256338;57216556340;7005966711;55451145400;8714367400;8443384400;56417185400;23500436000;57196288418;36120914800;23495616400;56191149300;57202206761;57196171210;7401663152;56921458500;57224357479;35757936600; |
Impact of the coronavirus disease 2019 pandemic on irritable bowel syndrome |
2021 |
Journal of Gastroenterology and Hepatology (Australia) |
36 |
8 |
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2187 |
2197 |
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4 |
https://www.scopus.com/inward/record.uri?eid=2-s2.0-85101935332&doi=10.1111%2fjgh.15466&partnerID=40&md5=4f7271b5d9e13c1b4bdea5a3463fd019 |
Department of Medicine, Yong Loo Lin School of Medicine, National University Hospital, Singapore; Department of Paediatrics, Yong Loo Lin School of Medicine, National University of Singapore, Singapore; Singapore Institute for Clinical Sciences, Agency for Science, Technology and Research, Singapore; Department of Clinical Psychology, James Cook University, Singapore; Division of Gastroenterology and Hepatology, Department of Medicine, National University Hospital, Singapore; Department of Medicine, Ng Teng Fong General Hospital, Singapore; Department of Otorhinolarygology, Head and Neck Surgery, Universiti Putra Malaysia, Seri Kembangan, Malaysia; Department of Anaesthesiology, Columbia Asia Hospital, Miri, Sarawak, Malaysia; Cambridge Paediatrics, Shatin, Hong Kong; Department of Gastroenterology, Sheikh Russel National Gastroliver Institute and Hospital, Dhaka, Bangladesh; Department of Gastroenterology, Sanjay Gandhi Postgraduate Institute Medical Science, Lucknow, India; Department of Medicine and Therapeutics, Faculty of Medicine, The Chinese University of Hong Kong, Shatin, Hong Kong; State Key Laboratory of Pharmaceutical Biotechnology, The University of Hong Kong, Hong Kong; Department of Medicine, The University of Hong Kong, Hong Kong; Division of Gastroenterology, Department of Internal Medicine, Faculty of Medicine, University of Indonesia/Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Departments of Gastroenterology and Hepatology, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou, China; Department of Gastroenterology, Wuhan Union Hospital of Huazhong University of Science and Technology, Wuhan, Hubei, China; Xiyuan Hospital, China Academy of Chinese Medical Sciences, Beijing, China; Department of Medicine, Buddhist Tzu Chi Hospital and University School of Medicine, Hualien, Taiwan; St George and Sutherland Clinical School, University of New South Wales, Sydney, NSW, Australia; Gut Research Group, Faculty of Medicine, Universiti Kebangsaan Malaysia, Kuala Lumpur, Malaysia; The Medical City, Metro Manila, Philippines; Wonkwang Digestive Disease Research Institute, Gut and Food Healthcare, Wonkwang University School of Medicine, Iksan, South Korea; Division of Gastroenterology and Hepatology, Department of Internal Medicine, Hyogo College of Medicine, Nishinomiya, Hyogo, Japan; Saw Swee Hock School of Public Health, National University of Singapore and National University Health System, Singapore; Centre for Infectious Disease Epidemiology and Research, National University of Singapore, Singapore |
Quek, S.X.Z., Department of Medicine, Yong Loo Lin School of Medicine, National University Hospital, Singapore; Loo, E.X.L., Department of Paediatrics, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore Institute for Clinical Sciences, Agency for Science, Technology and Research, Singapore; Demutska, A., Department of Clinical Psychology, James Cook University, Singapore; Chua, C.E., Department of Medicine, Yong Loo Lin School of Medicine, National University Hospital, Singapore; Kew, G.S., Department of Medicine, Yong Loo Lin School of Medicine, National University Hospital, Singapore, Division of Gastroenterology and Hepatology, Department of Medicine, National University Hospital, Singapore; Wong, S., Department of Medicine, Ng Teng Fong General Hospital, Singapore; Lau, H.X., Singapore Institute for Clinical Sciences, Agency for Science, Technology and Research, Singapore; Low, E.X.S., Department of Medicine, Ng Teng Fong General Hospital, Singapore; Loh, T.L., Department of Otorhinolarygology, Head and Neck Surgery, Universiti Putra Malaysia, Seri Kembangan, Malaysia; Lung, O.S., Department of Anaesthesiology, Columbia Asia Hospital, Miri, Sarawak, Malaysia; Hung, E.C.W., Cambridge Paediatrics, Shatin, Hong Kong; Rahman, M.M., Department of Gastroenterology, Sheikh Russel National Gastroliver Institute and Hospital, Dhaka, Bangladesh; Ghoshal, U.C., Department of Gastroenterology, Sanjay Gandhi Postgraduate Institute Medical Science, Lucknow, India; Wong, S.H., Department of Medicine and Therapeutics, Faculty of Medicine, The Chinese University of Hong Kong, Shatin, Hong Kong; Cheung, C.K.Y., State Key Laboratory of Pharmaceutical Biotechnology, The University of Hong Kong, Hong Kong, Department of Medicine, The University of Hong Kong, Hong Kong; Syam, A.F., Division of Gastroenterology, Department of Internal Medicine, Faculty of Medicine, University of Indonesia/Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Tan, N., Departments of Gastroenterology and Hepatology, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou, China; Xiao, Y., Departments of Gastroenterology and Hepatology, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou, China; Liu, J.-S., Department of Gastroenterology, Wuhan Union Hospital of Huazhong University of Science and Technology, Wuhan, Hubei, China; Lu, F., Xiyuan Hospital, China Academy of Chinese Medical Sciences, Beijing, China; Chen, C.-L., Department of Medicine, Buddhist Tzu Chi Hospital and University School of Medicine, Hualien, Taiwan; Lee, Y.Y., St George and Sutherland Clinical School, University of New South Wales, Sydney, NSW, Australia, Gut Research Group, Faculty of Medicine, Universiti Kebangsaan Malaysia, Kuala Lumpur, Malaysia; Maralit, R.M., The Medical City, Metro Manila, Philippines; Kim, Y.-S., Wonkwang Digestive Disease Research Institute, Gut and Food Healthcare, Wonkwang University School of Medicine, Iksan, South Korea; Oshima, T., Division of Gastroenterology and Hepatology, Department of Internal Medicine, Hyogo College of Medicine, Nishinomiya, Hyogo, Japan; Miwa, H., Saw Swee Hock School of Public Health, National University of Singapore and National University Health System, Singapore; Pang, J., Saw Swee Hock School of Public Health, National University of Singapore and National University Health System, Singapore, Centre for Infectious Disease Epidemiology and Research, National University of Singapore, Singapore; Siah, K.T.H., Department of Medicine, Yong Loo Lin School of Medicine, National University Hospital, Singapore, Division of Gastroenterology and Hepatology, Department of Medicine, National University Hospital, Singapore |
Background and Aim: Gastrointestinal manifestations of the coronavirus disease 2019 (COVID-19) pandemic may mimic irritable bowel syndrome (IBS), and social distancing measures may affect IBS patients negatively. We aimed to study the impact of COVID-19 on respondents with self-reported IBS. Methods: We conducted an anonymized survey from May to June 2020 in 33 countries. Knowledge, attitudes, and practices on personal hygiene and social distancing as well as psychological impact of COVID-19 were assessed. Statistical analysis was performed to determine differences in well-being and compliance to social distancing measures between respondents with and without self-reported IBS. Factors associated with improvement or worsening of IBS symptoms were evaluated. Results: Out of 2704 respondents, 2024 (74.9%) did not have IBS, 305 (11.3%) had self-reported IBS, and 374 (13.8%) did not know what IBS was. Self-reported IBS respondents reported significantly worse emotional, social, and psychological well-being compared with non-IBS respondents and were less compliant to social distancing measures (28.2% vs 35.3%, P = 0.029); 61.6% reported no change, 26.6% reported improvement, and 11.8% reported worsening IBS symptoms. Higher proportion of respondents with no change in IBS symptoms were willing to practice social distancing indefinitely versus those who deteriorated (74.9% vs 51.4%, P = 0.016). In multivariate analysis, willingness to continue social distancing for another 2–3 weeks (vs longer period) was significantly associated with higher odds of worsening IBS. Conclusion: Our study showed that self-reported IBS respondents had worse well-being and compliance to social distancing measures than non-IBS respondents. Future research will focus on occupational stress and dietary changes during COVID-19 that may influence IBS. © 2021 Journal of Gastroenterology and Hepatology Foundation and John Wiley & Sons Australia, Ltd |
COVID-19; IBS; Social distancing |
adult; Article; attitude to health; clinical assessment; clinical evaluation; clinical practice; comparative study; controlled study; coronavirus disease 2019; disease severity; emotion regulation; female; general condition deterioration; health survey; human; irritable colon; major clinical study; male; pandemic; personal hygiene; psychological aspect; psychological well-being; risk factor; self report; social distancing; symptom; clinical trial; cross-sectional study; irritable colon; multicenter study; pandemic; patient compliance; questionnaire; retrospective study; self report; Singapore; Adult; COVID-19; Cross-Sectional Studies; Female; Humans; Irritable Bowel Syndrome; Male; Pandemics; Patient Compliance; Retrospective Studies; SARS-CoV-2; Self Report; Singapore; Surveys and Questio |
John Wiley and Sons Inc |
08159319 |
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33615534 |
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