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Saharman Y.R., Karuniawati A., Sedono R., Aditianingsih D., Qi H., Verbrugh H.A., Severin J.A. |
55980934300;54886816200;56660590500;56312263600;57200516838;7103296623;8700385500; |
Multimodal intervention to reduce acquisition of carbapenem-non-susceptible Gram-negative bacteria in intensive care units in the National Referral Hospital of Indonesia: An interrupted time series study |
2021 |
Journal of Critical Care |
64 |
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237 |
244 |
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1 |
https://www.scopus.com/inward/record.uri?eid=2-s2.0-85107783916&doi=10.1016%2fj.jcrc.2021.04.016&partnerID=40&md5=5958a3646b6b7e60f517ca3456c7f72a |
Department of Clinical Microbiology, Faculty of Medicine, Universitas Indonesia/Dr. Cipto Mangunkusumo General Hospital, Jakarta, Indonesia; Department of Medical Microbiology and Infectious Diseases, Erasmus MC University Medical Center Rotterdam, Rotterdam, Netherlands; Critical Care Division, Department of Anesthesia and Intensive Care, Faculty of Medicine, Universitas Indonesia/Dr. Cipto Mangunkusumo General Hospital, Jakarta, Indonesia; Department of Biostatistics, Erasmus MC University Medical Center Rotterdam, Rotterdam, Netherlands; Department of Epidemiology, Erasmus MC University Medical Center Rotterdam, Rotterdam, Netherlands |
Saharman, Y.R., Department of Clinical Microbiology, Faculty of Medicine, Universitas Indonesia/Dr. Cipto Mangunkusumo General Hospital, Jakarta, Indonesia, Department of Medical Microbiology and Infectious Diseases, Erasmus MC University Medical Center Rotterdam, Rotterdam, Netherlands; Karuniawati, A., Department of Clinical Microbiology, Faculty of Medicine, Universitas Indonesia/Dr. Cipto Mangunkusumo General Hospital, Jakarta, Indonesia; Sedono, R., Critical Care Division, Department of Anesthesia and Intensive Care, Faculty of Medicine, Universitas Indonesia/Dr. Cipto Mangunkusumo General Hospital, Jakarta, Indonesia; Aditianingsih, D., Critical Care Division, Department of Anesthesia and Intensive Care, Faculty of Medicine, Universitas Indonesia/Dr. Cipto Mangunkusumo General Hospital, Jakarta, Indonesia; Qi, H., Department of Biostatistics, Erasmus MC University Medical Center Rotterdam, Rotterdam, Netherlands, Department of Epidemiology, Erasmus MC University Medical Center Rotterdam, Rotterdam, Netherlands; Verbrugh, H.A., Department of Medical Microbiology and Infectious Diseases, Erasmus MC University Medical Center Rotterdam, Rotterdam, Netherlands; Severin, J.A., Department of Medical Microbiology and Infectious Diseases, Erasmus MC University Medical Center Rotterdam, Rotterdam, Netherlands |
Purpose: To evaluate a low-cost multimodal intervention on the acquisition of carbapenem-non-susceptible Acinetobacter baumannii, Klebsiella pneumoniae, and Pseudomonas aeruginosa by patients in low-resource intensive care units. Materials and methods: We performed a quasi-experimental study in a referral hospital in Jakarta, Indonesia: pre-intervention phase 1 (2013–2014), intervention phase 2 (2014–2015) and post-intervention phase 3 (2015–2016). The intervention was hand hygiene promotion and environmental cleaning and disinfection combined with patient disinfection and cohorting. The primary outcome was acquisition of resistant bacteria per 100 patient-days at risk, which was assessed by active microbiological surveillance and analysed with a multilevel Poisson segmented regression model. Results: In phase 1 (387 patients), the acquisition rate was 4.3/100 days for carbapenem-non-susceptible A. baumannii versus 1.1/100 days for both K. pneumoniae and P. aeruginosa. There was a significant step change from phase 1 to phase 3 (361 patients) in the acquisition of carbapenem-non-susceptible strains, the incidence rate ratio (IRR) was 0.343 (99%CI: 0.164–0.717). This significant change was mainly due to reduced acquisitions of resistant A. baumannii (IRR 0.4, 99%CI: 0.181–1.061). Negative confounding was observed. Conclusion: A multimodal intervention to prevent acquisition of resistant pathogens is feasible and may be effective in ICUs in lower-middle income countries. © 2021 The Authors |
Acinetobacter baumannii-calcoaceticus complex; Acquisition rate; Carbapenem-non-susceptible; ICU; Indonesia; Klebsiella pneumoniae; Multimodal interventions; Pseudomonas aeruginosa |
carbapenem; antiinfective agent; carbapenem derivative; Acinetobacter baumannii; Acinetobacter calcoaceticus-baumannii complex; adult; aged; antibiotic sensitivity; Article; artificial ventilation; bacterium isolation; cleaning; controlled study; disease surveillance; disinfection; emergency ward; female; human; hygiene; incidence; infection control; information processing; intensive care unit; Klebsiella pneumoniae; length of stay; major clinical study; male; multidrug resistance; outcome assessment; phase 1 clinical trial; phase 2 clinical trial; phase 3 clinical trial; Pseudomonas aeruginosa; quasi experimental study; remission; Sequential Organ Failure Assessment Score; systemic inflammatory response syndrome; time series analysis; cross infection; Gram negative bacterium; hospital; In |
W.B. Saunders |
08839441 |
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34044188 |
Article |
Q1 |
1149 |
3541 |
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261 |
Pravian D., Soesanto A.M., Ambari A.M., Kuncoro B.R.M.A.S., Dwiputra B., Muliawan H.S., Sukmawan R. |
57223935749;56374199000;57189576921;57223920990;57195383994;57203644653;8651025300; |
The effect of external counterpulsation on intrinsic myocardial function evaluated by speckle tracking echocardiography in refractory angina patients: a randomized controlled trial |
2021 |
International Journal of Cardiovascular Imaging |
37 |
8 |
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2483 |
2490 |
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1 |
https://www.scopus.com/inward/record.uri?eid=2-s2.0-85106531230&doi=10.1007%2fs10554-021-02289-x&partnerID=40&md5=205259fb7afb6a50c7b9b375ac603918 |
Department of Cardiology and Vascular Medicine, Faculty of Medicine, Universitas Indonesia/National Cardiovascular Center Harapan Kita, Jakarta, Indonesia |
Pravian, D., Department of Cardiology and Vascular Medicine, Faculty of Medicine, Universitas Indonesia/National Cardiovascular Center Harapan Kita, Jakarta, Indonesia; Soesanto, A.M., Department of Cardiology and Vascular Medicine, Faculty of Medicine, Universitas Indonesia/National Cardiovascular Center Harapan Kita, Jakarta, Indonesia; Ambari, A.M., Department of Cardiology and Vascular Medicine, Faculty of Medicine, Universitas Indonesia/National Cardiovascular Center Harapan Kita, Jakarta, Indonesia; Kuncoro, B.R.M.A.S., Department of Cardiology and Vascular Medicine, Faculty of Medicine, Universitas Indonesia/National Cardiovascular Center Harapan Kita, Jakarta, Indonesia; Dwiputra, B., Department of Cardiology and Vascular Medicine, Faculty of Medicine, Universitas Indonesia/National Cardiovascular Center Harapan Kita, Jakarta, Indonesia; Muliawan, H.S., Department of Cardiology and Vascular Medicine, Faculty of Medicine, Universitas Indonesia/National Cardiovascular Center Harapan Kita, Jakarta, Indonesia; Sukmawan, R., Department of Cardiology and Vascular Medicine, Faculty of Medicine, Universitas Indonesia/National Cardiovascular Center Harapan Kita, Jakarta, Indonesia |
External Counterpulsation (ECP) is one of the therapeutic options in patients with refractory angina inadequately controlled by medical, interventional, or surgical therapy. The 2D Speckle Tracking Echocardiography (2D-STE) method is considered superior in assessing clinical improvement. We would like to evaluate any improvement of myocardial intrinsic function using 2D-STE in patients underwent standard ECP protocol (35 sessions). We conducted a double-blind randomized controlled trial. Patients with refractory angina who could not be revascularized conventionally were randomized into two groups: (1) the ECP group (300 mmHg) and (2) the Sham/control group (75 mmHg). ECP standard therapy was given for 35 sessions (1 h/day/session). The 2D-STE data, including longitudinal strain and post systolic index (PSI) were obtained before and after therapy. 43 subjects were analyzed, with 22 subjects in ECP group and 21 control subjects (Sham group). A homogenous baseline strain was found either globally (12.42 ± 4.55 vs 12.00 ± 4.92 [− %]; P = 0.774) or segmentally/regionally (12.63 (0.01–25.16) vs 12.43 (0.01–27.20) [− %]; P = 0.570). There was no statistically significant improvement between groups in the left ventricle longitudinal strain globally (P = 0.535) and segmentally/regionally (P = 0.434). PSI parameters showed improvement in the ECP group (P = 0.049), and segments with PSI ≥ 20% seemed to improve longitudinal strains in the ECP group after therapy (P = 0.042). In conclusion, 35 ECP therapy sessions did not improve either global or segmental/regional left ventricular mechanical function in patients with refractory angina. However, the mechanical function of myocardial segments with PSS tends to improve after ECP therapy. © 2021, The Author(s), under exclusive licence to Springer Nature B.V. |
2D speckle tracking echocardiography; External counterpulsation; Post systolic index; Refractory angina; Strain |
adult; aged; angina pectoris; Article; cardiovascular parameters; clinical article; clinical outcome; controlled study; counterpulsation; double blind procedure; female; follow up; heart function; heart left ventricle enddiastolic diameter; heart left ventricle endsystolic diameter; human; left ventricular global longitudinal strain; male; middle aged; post systolic index; post systolic shortening; randomized controlled trial; tricuspid annular plane systolic excursion; two dimensional speckle tracking echocardiography |
Springer Science and Business Media B.V. |
15695794 |
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34037889 |
Article |
Q2 |
726 |
6821 |
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263 |
Yunihastuti E., Lestari Agusin R., Sari V., Jhariah Hidayah A., Wulunggono W., Pramukti H., Shinta M., Shatri H., Harjono Karjadi T. |
57221273925;57223400304;57223400647;57223397657;57211629741;57223395589;57223397294;28767986500;57223406089; |
Prevalence and associated factors of depressive symptoms among people living with HIV on antiretroviral therapy in Jakarta, Indonesia |
2021 |
Tropical Medicine and International Health |
26 |
8 |
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908 |
915 |
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https://www.scopus.com/inward/record.uri?eid=2-s2.0-85105775227&doi=10.1111%2ftmi.13597&partnerID=40&md5=56c4f01a1cfbf229aaa3658813422100 |
Department of Internal Medicine, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; HIV Integrated Unit RSUPN Dr Cipto Mangunkusumo Hospital, Jakarta, Indonesia |
Yunihastuti, E., Department of Internal Medicine, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia, HIV Integrated Unit RSUPN Dr Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Lestari Agusin, R., Department of Internal Medicine, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Sari, V., Department of Internal Medicine, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Jhariah Hidayah, A., HIV Integrated Unit RSUPN Dr Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Wulunggono, W., Department of Internal Medicine, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Pramukti, H., Department of Internal Medicine, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Shinta, M., HIV Integrated Unit RSUPN Dr Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Shatri, H., Department of Internal Medicine, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Harjono Karjadi, T., Department of Internal Medicine, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia, HIV Integrated Unit RSUPN Dr Cipto Mangunkusumo Hospital, Jakarta, Indonesia |
Objective: We aimed to investigate the prevalence of depressive symptoms among people living with HIV (PLHIV) on antiretroviral therapy (ART) in a large HIV treatment facility in Jakarta, Indonesia, and to assess associated factors. Methods: The Indonesian version of Beck Depression Inventory-II was used to assess depressive symptoms of 346 participants visiting the HIV Integrated Clinic Cipto Mangunkusumo hospital between June and November 2018. Results: Depressive symptoms (BDI-II score ≥14) were exhibited by 50.9% of participants, with prevalences of mild, moderate and severe depression of 30.4%, 15.6% and 4.9%, respectively. Poisson regression with robust variance analysis indicated that having lower income (aPR = 1.38, 95% CI 1.12–1.63), duration of ART for 1–5 years (aPR = 1.25, 95% CI 1.01–1.54) and same-sex partnership (aPR = 1.27, 95% CI 1.02–1.58) were positively associated with depressive symptoms. Age, sex and history of using intravenous drugs, and ART-based regimen were not associated with depressive symptoms. Conclusions: Depressive symptoms were common among our population despite long-term ART use and were associated with having low-income, ART for 1–5 years and same-sex partnership. © 2021 John Wiley & Sons Ltd |
antiretroviral therapy; depression; depressive symptoms; human immunodeficiency virus |
anti human immunodeficiency virus agent; disease prevalence; mental health; spatiotemporal analysis; symptom; variance analysis; adult; age; analysis of variance; antiretroviral therapy; Article; Beck Depression Inventory; confidence interval; controlled study; cross-sectional study; depression; disease association; disease severity; female; human; Human immunodeficiency virus infected patient; Human immunodeficiency virus infection; Indonesia; intravenous drug abuse; lowest income group; major clinical study; male; medical history; Poisson distribution; prevalence; sex; depression; highly active antiretroviral therapy; Indonesia; prevalence; psychology; psychometry; risk factor; Indonesia; Jakarta; Human immunodeficiency virus; Adult; Antiretroviral Therapy, Highly Active; Cross-Sectional |
John Wiley and Sons Inc |
13602276 |
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33930230 |
Article |
Q1 |
1056 |
4040 |
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264 |
Lesmana C.R.A., Mandasari B.K.D. |
8977683000;57223222627; |
The new era of endoscopic ultrasound in biliary disorders |
2021 |
Clinical Journal of Gastroenterology |
14 |
4 |
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923 |
931 |
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https://www.scopus.com/inward/record.uri?eid=2-s2.0-85105339459&doi=10.1007%2fs12328-021-01419-1&partnerID=40&md5=e46386a86669ce1318bf2c07a7eeb843 |
Division of Hepatobiliary, Department of Internal Medicine, Dr. Cipto Mangunkusumo National General Hospital, Medical Faculty Universitas Indonesia, JL. Diponegoro 71, Jakarta, DKI Jakarta 10430, Indonesia; Digestive Disease & GI Oncology Centre, Medistra Hospital, Jakarta, Indonesia |
Lesmana, C.R.A., Division of Hepatobiliary, Department of Internal Medicine, Dr. Cipto Mangunkusumo National General Hospital, Medical Faculty Universitas Indonesia, JL. Diponegoro 71, Jakarta, DKI Jakarta 10430, Indonesia, Digestive Disease & GI Oncology Centre, Medistra Hospital, Jakarta, Indonesia; Mandasari, B.K.D., Division of Hepatobiliary, Department of Internal Medicine, Dr. Cipto Mangunkusumo National General Hospital, Medical Faculty Universitas Indonesia, JL. Diponegoro 71, Jakarta, DKI Jakarta 10430, Indonesia |
Biliary obstruction is one of challenging biliary disorders in gastroenterology field, where this long-standing condition can also lead to portal hypertension and multi-disciplinary teamwork is usually needed to manage this problem. Biliary drainage is the primary management to prevent prolonged cholestasis. Biliary system with its thin-walled and tubular structure sometimes makes the diagnosis and therapeutic not easy to approach. Over the past 3 decades, numerous new and modern diagnostic and therapeutic modalities have been developed to manage the complex biliary problems. It is well known that endoscopic retrograde cholangiopancreatography (ERCP), percutaneous transhepatic biliary drainage (PTBD), and surgical procedure are common procedures in managing biliary disorders. However, surgical therapy and ERCP are not always easy to perform due to several contraindications. Because of difficulty in performing these procedures or unavailability of these procedures in the facility, PTBD, as the primary non-surgical procedure of choice, has been popular due to its easy technique. Endoscopic ultrasound (EUS) has evolved significantly not only as a diagnostic tool for identification and staging, but also for interventional approaches, especially in management of biliary malignancy. Recently, EUS-guided biliary drainage (EUS-BD) and EUS-guided gallbladder drainage (EUS-GBD) are developed for managing biliary disorders. Whether EUS can be useful for managing biliary obstruction as a primary procedure is still controversial. Hence, a large number of further studies are required to validate. © 2021, Japanese Society of Gastroenterology. |
Biliary obstruction; Endoscopic ultrasound (EUS); EUS-guided biliary drainage (EUS-BD); EUS-guided gallbladder drainage (EUS-GBD); Portal hypertension |
biliary tract disease; biliary tract drainage; cholestasis; endoscopic retrograde cholangiopancreatography; endoscopic ultrasonography; examination; gallbladder drainage; history of medicine; human; interventional ultrasonography; nonhuman; percutaneous transhepatic drainage; portal hypertension; Review; screening; biliary tract tumor; cholestasis; diagnostic imaging; endoscopic ultrasonography; Biliary Tract Neoplasms; Cholangiopancreatography, Endoscopic Retrograde; Cholestasis; Drainage; Endosonography; Humans |
Springer Japan |
18657257 |
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33895970 |
Review |
Q3 |
414 |
11779 |
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265 |
Yuliwulandari R., Shin J.G., Kristin E., Suyatna F.D., Prahasto I.D., Prayuni K., Mahasirimongkol S., Cavallari L.H., Mitropoulou C., Patrinos G.P., Hao J., Williams M.S., Snyder S.R. |
23098874600;56031235700;6504458442;56039633100;57222660319;57190022456;14632559000;8396168500;37001846100;6603726539;57194283820;57203332674;7401687524; |
Cost-effectiveness analysis of genotyping for HLA-B*15:02 in Indonesian patients with epilepsy using a generic model |
2021 |
Pharmacogenomics Journal |
21 |
4 |
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476 |
483 |
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1 |
https://www.scopus.com/inward/record.uri?eid=2-s2.0-85103643380&doi=10.1038%2fs41397-021-00225-9&partnerID=40&md5=927cb9a5fa739ff5a932d25eb4459bd0 |
Department of Pharmacology, Faculty of Medicine, YARSI University, Jakarta Pusat, Indonesia; Genetic Research Center, YARSI Research Institute, YARSI University, Jakarta Pusat, Indonesia; Department of Pharmacology and Pharmacogenomics Research Center, Inje University College of Medicine, Busan, South Korea; Department of Clinical Pharmacology, Inje University Busan Paik Hospital, Busan, South Korea; Department of Pharmacology and Therapy, Faculty of Medicine, Gadjah Mada University, Yogyakarta, Indonesia; Department of Pharmacology & Therapeutic, Faculty of Medicine, Universitas Indonesia, Jakarta Pusat, Indonesia; Medical Genetics Section, Department of Medical Sciences, Ministry of Public Health, Nonthaburi, Thailand; Department of Pharmacotherapy and Translational Research, University of Florida, Gainesville, FL, United States; The Golden Helix Foundation, London, United Kingdom; Department of Pharmacy, University of Patras, Patras, Greece; Department of Pathology, United Arab Emirates University College of Medicine and Health Sciences, Al-Ain, United Arab Emirates; Department of Population Health Sciences, Geisinger, Danville, PA, United States; Genomic Medicine Institute, Geisinger, Danville, PA, United States; Health Policy & Behavioral Sciences, Georgia State University, Atlanta, GA, United States |
Yuliwulandari, R., Department of Pharmacology, Faculty of Medicine, YARSI University, Jakarta Pusat, Indonesia, Genetic Research Center, YARSI Research Institute, YARSI University, Jakarta Pusat, Indonesia; Shin, J.G., Department of Pharmacology and Pharmacogenomics Research Center, Inje University College of Medicine, Busan, South Korea, Department of Clinical Pharmacology, Inje University Busan Paik Hospital, Busan, South Korea; Kristin, E., Department of Pharmacology and Therapy, Faculty of Medicine, Gadjah Mada University, Yogyakarta, Indonesia; Suyatna, F.D., Department of Pharmacology & Therapeutic, Faculty of Medicine, Universitas Indonesia, Jakarta Pusat, Indonesia; Prahasto, I.D., Department of Pharmacology and Therapy, Faculty of Medicine, Gadjah Mada University, Yogyakarta, Indonesia; Prayuni, K., Genetic Research Center, YARSI Research Institute, YARSI University, Jakarta Pusat, Indonesia; Mahasirimongkol, S., Medical Genetics Section, Department of Medical Sciences, Ministry of Public Health, Nonthaburi, Thailand; Cavallari, L.H., Department of Pharmacotherapy and Translational Research, University of Florida, Gainesville, FL, United States; Mitropoulou, C., The Golden Helix Foundation, London, United Kingdom; Patrinos, G.P., Department of Pharmacy, University of Patras, Patras, Greece, Department of Pathology, United Arab Emirates University College of Medicine and Health Sciences, Al-Ain, United Arab Emirates; Hao, J., Department of Population Health Sciences, Geisinger, Danville, PA, United States; Williams, M.S., Genomic Medicine Institute, Geisinger, Danville, PA, United States; Snyder, S.R., Health Policy & Behavioral Sciences, Georgia State University, Atlanta, GA, United States |
Carbamazepine (CBZ)-induced Stevens–Johnson syndrome and toxic epidermal necrolysis (SJS/TEN) are strongly associated with the HLA-B*15:02 allele. Screening HLA-B*15:02 before CBZ administration might prevent CBZ-induced SJS/TEN by enabling clinicians to prescribe alternative therapy for positive patients. Similar to other Southeastern Asian countries, HLA-B*15:02 is highly prevalent in Indonesia. Therefore, we assessed the economic value of HLA-B*15:02 screening before CBZ prescription to patients with epilepsy in Indonesia. A generic cost-effectiveness model and decision support tool, developed to enable users to perform an initial cost-effectiveness analysis from a healthcare provider/payer perspective, were used to assess the value of HLA-B*15:02 genotyping. The incremental cost-effectiveness ratio of adopting universal HLA-B*15:02 screening was 656,444,671 Indonesian Rupiah (IDR)/quality-adjusted life year (QALY) gained for patients compared with 2,634,975,574 IDR/QALY gained for providing valproic acid (alternative drug) without screening. Thus, neither HLA-B*15:02 screening nor substitution with VPA meets the Indonesian threshold for cost effectiveness. However, the improved outcomes with this test in other Asian countries may inform the desirability of implementation in Indonesia even with suboptimal cost-effectiveness. © 2021, The Author(s), under exclusive licence to Springer Nature Limited. |
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anticonvulsive agent; carbamazepine; HLA B antigen; valproic acid; anticonvulsive agent; carbamazepine; HLA B15 antigen; aged; Article; cost effectiveness analysis; epilepsy; epileptic patient; female; genotyping; human; Indonesian; Javanese (people); major clinical study; male; predictive value; prevalence; quality adjusted life year; sensitivity analysis; sensitivity and specificity; Stevens Johnson syndrome; Sundanese (people); toxic epidermal necrolysis; adult; allele; Asian; cost benefit analysis; epilepsy; genetic predisposition; genetic screening; genetics; genotype; Indonesia; procedures; risk factor; Adult; Alleles; Anticonvulsants; Asians; Carbamazepine; Cost-Benefit Analysis; Epilepsy; Female; Genetic Predisposition to Disease; Genetic Testing; Genotype; HLA-B15 Antigen; Humans; |
Springer Nature |
1470269X |
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33824430 |
Article |
Q2 |
804 |
6015 |
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266 |
Akada J., Tshibangu-Kabamba E., Tuan V.P., Kurogi S., Matsuo Y., Ansari S., Doohan D., Phuc B.H., Subsomwong P., Waskito L.A., Binh T.T., Nguyen L.T., Khien V.V., Dung H.D.Q., Miftahussurur M., Syam A.F., Tshering L., Vilaichone R.-K., Mahachai V., Ratanachu-ek T., Shrestha P.K., Yee T.T., Htet K., Aftab H., Matsuhisa T., Uchida T., Okimoto T., Mizukami K., Kodama M., Murakami K., Takahashi N., Yamaoka Y. |
6506986959;57218760439;57195367045;57195277760;55567953900;55523204000;57204644036;57222165127;57113712700;57192177367;55415987700;35285702000;6507745643;56681908900;56323903000;8443384400;57211294242;6701788898;7003739875;6507122700;8099897200;57211455497;57241639000;55359226800;7005493709;35286123100;7005300232;7005239531;35285903900;57214336895;7403938865;55183784100; |
Serum Helicobacter pylori antibody reactivity in seven Asian countries using an automated latex aggregation turbidity assay |
2021 |
Journal of Gastroenterology and Hepatology (Australia) |
36 |
8 |
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2198 |
2209 |
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2 |
https://www.scopus.com/inward/record.uri?eid=2-s2.0-85102320750&doi=10.1111%2fjgh.15467&partnerID=40&md5=71760e350adacfbf3a65094e953e8182 |
Department of Environmental and Preventive Medicine, Faculty of Medicine, Oita University, Yufu, Japan; Clinical Laboratory Center, Oita University Hospital, Yufu, Japan; Department of Endoscopy, Cho Ray Hospital, Ho Chi Minh City, Viet Nam; Department of Hepatogastroenterology, 108 Military Central Hospital, Hanoi, Viet Nam; Institute of Tropical Disease, Airlangga University, Surabaya, Indonesia; Gastroentero-Hepatology Division, Department of Internal Medicine, Faculty of Medicine-Dr. Soetomo Teaching Hospital, Airlangga University, Surabaya, Indonesia; Division of Gastroenterology, Department of Intestinal Medicine, Faculty of Medicine, University of Indonesia, Jakarta, Indonesia; Department of Surgery, Jigme Dorji Wangchuck National Referral Hospital, Thimphu, Bhutan; Gastroenterology Unit, Digestive Diseases Research Center, Thammasat University Hospital, Khlong Luang, Thailand; Department of Medicine, Chulabhorn International College of Medicine, Thammasat University Hospital, Khlong Luang, Thailand; GI and Liver Center, Bangkok Medical Center, Bangkok, Thailand; Department of Surgery, Rajavithi Hospital, Bangkok, Thailand; Department of Gastroenterology, Maharajgunj Medical Campus, Tribhuvan University Teaching Hospital, Kathmandu, Nepal; Department of GI and HBP Surgery, No (2) Defense Service General Hospital, Nay Pyi Taw, Myanmar; Department of GI and HBP Surgery, No (1) Defense Service General Hospital, Mingaladon, Myanmar; Department of Gastroenterology, Dhaka Medical Collage and Hospital, Dhaka, Bangladesh; Department of Gastroenterology, Tama-Nagayama University Hospital, Nippon Medical School, Tama, Japan; Department of Molecular Pathology, Faculty of Medicine, Oita University, Yufu, Japan; Department of Gastroenterology, Faculty of Medicine, Oita University, Yufu, Japan; Faculty of Welfare and Health Science, Oita University, Yufu, Japan; Global Oita Medical Advanced Research Center for Health, Oita University, Yufu, Japan; Department of Medicine, Gastroenterology and Hepatology Section, Baylor College of Medicine, Houston, TX, United States |
Akada, J., Department of Environmental and Preventive Medicine, Faculty of Medicine, Oita University, Yufu, Japan; Tshibangu-Kabamba, E., Department of Environmental and Preventive Medicine, Faculty of Medicine, Oita University, Yufu, Japan; Tuan, V.P., Department of Environmental and Preventive Medicine, Faculty of Medicine, Oita University, Yufu, Japan, Department of Endoscopy, Cho Ray Hospital, Ho Chi Minh City, Viet Nam; Kurogi, S., Clinical Laboratory Center, Oita University Hospital, Yufu, Japan, Department of Molecular Pathology, Faculty of Medicine, Oita University, Yufu, Japan; Matsuo, Y., Department of Environmental and Preventive Medicine, Faculty of Medicine, Oita University, Yufu, Japan; Ansari, S., Department of Environmental and Preventive Medicine, Faculty of Medicine, Oita University, Yufu, Japan; Doohan, D., Department of Environmental and Preventive Medicine, Faculty of Medicine, Oita University, Yufu, Japan, Institute of Tropical Disease, Airlangga University, Surabaya, Indonesia; Phuc, B.H., Department of Environmental and Preventive Medicine, Faculty of Medicine, Oita University, Yufu, Japan; Subsomwong, P., Department of Environmental and Preventive Medicine, Faculty of Medicine, Oita University, Yufu, Japan; Waskito, L.A., Department of Environmental and Preventive Medicine, Faculty of Medicine, Oita University, Yufu, Japan, Institute of Tropical Disease, Airlangga University, Surabaya, Indonesia; Binh, T.T., Department of Endoscopy, Cho Ray Hospital, Ho Chi Minh City, Viet Nam; Nguyen, L.T., Department of Hepatogastroenterology, 108 Military Central Hospital, Hanoi, Viet Nam; Khien, V.V., Department of Hepatogastroenterology, 108 Military Central Hospital, Hanoi, Viet Nam; Dung, H.D.Q., Department of Endoscopy, Cho Ray Hospital, Ho Chi Minh City, Viet Nam; Miftahussurur, M., Institute of Tropical Disease, Airlangga University, Surabaya, Indonesia, Gastroentero-Hepatology Division, Department of Internal Medicine, Faculty of Medicine-Dr. Soetomo Teaching Hospital, Airlangga University, Surabaya, Indonesia; Syam, A.F., Division of Gastroenterology, Department of Intestinal Medicine, Faculty of Medicine, University of Indonesia, Jakarta, Indonesia; Tshering, L., Department of Surgery, Jigme Dorji Wangchuck National Referral Hospital, Thimphu, Bhutan; Vilaichone, R.-K., Gastroenterology Unit, Digestive Diseases Research Center, Thammasat University Hospital, Khlong Luang, Thailand, Department of Medicine, Chulabhorn International College of Medicine, Thammasat University Hospital, Khlong Luang, Thailand; Mahachai, V., GI and Liver Center, Bangkok Medical Center, Bangkok, Thailand; Ratanachu-ek, T., Department of Surgery, Rajavithi Hospital, Bangkok, Thailand; Shrestha, P.K., Department of Gastroenterology, Maharajgunj Medical Campus, Tribhuvan University Teaching Hospital, Kathmandu, Nepal; Yee, T.T., Department of GI and HBP Surgery, No (2) Defense Service General Hospital, Nay Pyi Taw, Myanmar; Htet, K., Department of GI and HBP Surgery, No (1) Defense Service General Hospital, Mingaladon, Myanmar; Aftab, H., Department of Gastroenterology, Dhaka Medical Collage and Hospital, Dhaka, Bangladesh; Matsuhisa, T., Department of Gastroenterology, Tama-Nagayama University Hospital, Nippon Medical School, Tama, Japan; Uchida, T., Department of Molecular Pathology, Faculty of Medicine, Oita University, Yufu, Japan; Okimoto, T., Department of Gastroenterology, Faculty of Medicine, Oita University, Yufu, Japan; Mizukami, K., Department of Gastroenterology, Faculty of Medicine, Oita University, Yufu, Japan; Kodama, M., Department of Gastroenterology, Faculty of Medicine, Oita University, Yufu, Japan, Faculty of Welfare and Health Science, Oita University, Yufu, Japan; Murakami, K., Department of Gastroenterology, Faculty of Medicine, Oita University, Yufu, Japan; Takahashi, N., Clinical Laboratory Center, Oita University Hospital, Yufu, Japan; Yamaoka, Y., Department of Environmental and Preventive Medicine, Faculty of Medicine, Oita University, Yufu, Japan, Global Oita Medical Advanced Research Center for Health, Oita University, Yufu, Japan, Department of Medicine, Gastroenterology and Hepatology Section, Baylor College of Medicine, Houston, TX, United States |
Background and Aim: To determine the application range of diagnostic kits utilizing anti-Helicobacter pylori antibody, we tested a newly developed latex aggregation turbidity assay (latex) and a conventional enzyme-linked immunosorbent assay (E-plate), both containing Japanese H. pylori protein lysates as antigens, using sera from seven Asian countries. Methods: Serum samples (1797) were obtained, and standard H. pylori infection status and atrophy status were determined by culture and histology (immunohistochemistry) using gastric biopsy samples from the same individuals. The two tests (enzyme-linked immunosorbent assay and latex) were applied, and receiver operating characteristics analysis was performed. Results: Area under the curve (AUC) from the receiver operating characteristic of E-plate and latex curves were almost the same and the highest in Vietnam. The latex AUC was slightly lower than the E-plate AUC in other countries, and the difference became statistically significant in Myanmar and then Bangladesh as the lowest. To consider past infection cases, atrophy was additionally evaluated. Most of the AUCs decreased using this atrophy-evaluated status; however, the difference between the two kits was not significant in each country, but the latex AUC was better using all samples. Practical cut-off values were 3.0 U/mL in the E-test and 3.5 U/mL in the latex test, to avoid missing gastric cancer patients to the greatest extent possible. Conclusions: The kits were applicable in all countries, but new kits using regional H. pylori strains are recommended for Myanmar and Bangladesh. Use of a cut-off value lower than the best cut-off value is essential for screening gastric cancer patients. © 2021 Journal of Gastroenterology and Hepatology Foundation and John Wiley & Sons Australia, Ltd |
Asia; ELISA; Helicobacter pylori; Latex aggregation turbidity assay; Serum antibody |
antigen; bacterium antibody; immunoglobulin G; protein hydrolysate; bacterium antibody; adult; antibody blood level; Article; Asia; bacterial strain; bacterium culture; Bangladesh; Bhutan; cancer patient; cancer screening; controlled study; diagnostic accuracy; diagnostic test; evaluation study; female; Helicobacter infection; Helicobacter pylori; histopathology; human; human tissue; immunohistochemistry; Indonesia; infection rate; Japan; latex aggregation turbidity assay; major clinical study; male; marginal zone lymphoma; middle aged; Myanmar; Nepal; nonhuman; plate ELISA; predictive value; receiver operating characteristic; reference value; sensitivity and specificity; serum; statistical significance; stomach atrophy; stomach biopsy; stomach cancer; Viet Nam; aged; atrophy; biopsy; bloo |
John Wiley and Sons Inc |
08159319 |
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33609333 |
Article |
Q1 |
1214 |
3242 |
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267 |
Quek S.X.Z., Loo E.X.L., Demutska A., Chua C.E., Kew G.S., Wong S., Lau H.X., Low E.X.S., Loh T.L., Lung O.S., Hung E.C.W., Rahman M.M., Ghoshal U.C., Wong S.H., Cheung C.K.Y., Syam A.F., Tan N., Xiao Y., Liu J.-S., Lu F., Chen C.-L., Lee Y.Y., Maralit R.M., Kim Y.-S., Oshima T., Miwa H., Pang J., Siah K.T.H. |
57222222782;50162082500;36136970000;56816437200;56611839100;57222223736;57218857855;57201335892;57222224359;57222226377;7004256338;57216556340;7005966711;55451145400;8714367400;8443384400;56417185400;23500436000;57196288418;36120914800;23495616400;56191149300;57202206761;57196171210;7401663152;56921458500;57224357479;35757936600; |
Impact of the coronavirus disease 2019 pandemic on irritable bowel syndrome |
2021 |
Journal of Gastroenterology and Hepatology (Australia) |
36 |
8 |
|
2187 |
2197 |
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4 |
https://www.scopus.com/inward/record.uri?eid=2-s2.0-85101935332&doi=10.1111%2fjgh.15466&partnerID=40&md5=4f7271b5d9e13c1b4bdea5a3463fd019 |
Department of Medicine, Yong Loo Lin School of Medicine, National University Hospital, Singapore; Department of Paediatrics, Yong Loo Lin School of Medicine, National University of Singapore, Singapore; Singapore Institute for Clinical Sciences, Agency for Science, Technology and Research, Singapore; Department of Clinical Psychology, James Cook University, Singapore; Division of Gastroenterology and Hepatology, Department of Medicine, National University Hospital, Singapore; Department of Medicine, Ng Teng Fong General Hospital, Singapore; Department of Otorhinolarygology, Head and Neck Surgery, Universiti Putra Malaysia, Seri Kembangan, Malaysia; Department of Anaesthesiology, Columbia Asia Hospital, Miri, Sarawak, Malaysia; Cambridge Paediatrics, Shatin, Hong Kong; Department of Gastroenterology, Sheikh Russel National Gastroliver Institute and Hospital, Dhaka, Bangladesh; Department of Gastroenterology, Sanjay Gandhi Postgraduate Institute Medical Science, Lucknow, India; Department of Medicine and Therapeutics, Faculty of Medicine, The Chinese University of Hong Kong, Shatin, Hong Kong; State Key Laboratory of Pharmaceutical Biotechnology, The University of Hong Kong, Hong Kong; Department of Medicine, The University of Hong Kong, Hong Kong; Division of Gastroenterology, Department of Internal Medicine, Faculty of Medicine, University of Indonesia/Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Departments of Gastroenterology and Hepatology, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou, China; Department of Gastroenterology, Wuhan Union Hospital of Huazhong University of Science and Technology, Wuhan, Hubei, China; Xiyuan Hospital, China Academy of Chinese Medical Sciences, Beijing, China; Department of Medicine, Buddhist Tzu Chi Hospital and University School of Medicine, Hualien, Taiwan; St George and Sutherland Clinical School, University of New South Wales, Sydney, NSW, Australia; Gut Research Group, Faculty of Medicine, Universiti Kebangsaan Malaysia, Kuala Lumpur, Malaysia; The Medical City, Metro Manila, Philippines; Wonkwang Digestive Disease Research Institute, Gut and Food Healthcare, Wonkwang University School of Medicine, Iksan, South Korea; Division of Gastroenterology and Hepatology, Department of Internal Medicine, Hyogo College of Medicine, Nishinomiya, Hyogo, Japan; Saw Swee Hock School of Public Health, National University of Singapore and National University Health System, Singapore; Centre for Infectious Disease Epidemiology and Research, National University of Singapore, Singapore |
Quek, S.X.Z., Department of Medicine, Yong Loo Lin School of Medicine, National University Hospital, Singapore; Loo, E.X.L., Department of Paediatrics, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore Institute for Clinical Sciences, Agency for Science, Technology and Research, Singapore; Demutska, A., Department of Clinical Psychology, James Cook University, Singapore; Chua, C.E., Department of Medicine, Yong Loo Lin School of Medicine, National University Hospital, Singapore; Kew, G.S., Department of Medicine, Yong Loo Lin School of Medicine, National University Hospital, Singapore, Division of Gastroenterology and Hepatology, Department of Medicine, National University Hospital, Singapore; Wong, S., Department of Medicine, Ng Teng Fong General Hospital, Singapore; Lau, H.X., Singapore Institute for Clinical Sciences, Agency for Science, Technology and Research, Singapore; Low, E.X.S., Department of Medicine, Ng Teng Fong General Hospital, Singapore; Loh, T.L., Department of Otorhinolarygology, Head and Neck Surgery, Universiti Putra Malaysia, Seri Kembangan, Malaysia; Lung, O.S., Department of Anaesthesiology, Columbia Asia Hospital, Miri, Sarawak, Malaysia; Hung, E.C.W., Cambridge Paediatrics, Shatin, Hong Kong; Rahman, M.M., Department of Gastroenterology, Sheikh Russel National Gastroliver Institute and Hospital, Dhaka, Bangladesh; Ghoshal, U.C., Department of Gastroenterology, Sanjay Gandhi Postgraduate Institute Medical Science, Lucknow, India; Wong, S.H., Department of Medicine and Therapeutics, Faculty of Medicine, The Chinese University of Hong Kong, Shatin, Hong Kong; Cheung, C.K.Y., State Key Laboratory of Pharmaceutical Biotechnology, The University of Hong Kong, Hong Kong, Department of Medicine, The University of Hong Kong, Hong Kong; Syam, A.F., Division of Gastroenterology, Department of Internal Medicine, Faculty of Medicine, University of Indonesia/Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Tan, N., Departments of Gastroenterology and Hepatology, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou, China; Xiao, Y., Departments of Gastroenterology and Hepatology, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou, China; Liu, J.-S., Department of Gastroenterology, Wuhan Union Hospital of Huazhong University of Science and Technology, Wuhan, Hubei, China; Lu, F., Xiyuan Hospital, China Academy of Chinese Medical Sciences, Beijing, China; Chen, C.-L., Department of Medicine, Buddhist Tzu Chi Hospital and University School of Medicine, Hualien, Taiwan; Lee, Y.Y., St George and Sutherland Clinical School, University of New South Wales, Sydney, NSW, Australia, Gut Research Group, Faculty of Medicine, Universiti Kebangsaan Malaysia, Kuala Lumpur, Malaysia; Maralit, R.M., The Medical City, Metro Manila, Philippines; Kim, Y.-S., Wonkwang Digestive Disease Research Institute, Gut and Food Healthcare, Wonkwang University School of Medicine, Iksan, South Korea; Oshima, T., Division of Gastroenterology and Hepatology, Department of Internal Medicine, Hyogo College of Medicine, Nishinomiya, Hyogo, Japan; Miwa, H., Saw Swee Hock School of Public Health, National University of Singapore and National University Health System, Singapore; Pang, J., Saw Swee Hock School of Public Health, National University of Singapore and National University Health System, Singapore, Centre for Infectious Disease Epidemiology and Research, National University of Singapore, Singapore; Siah, K.T.H., Department of Medicine, Yong Loo Lin School of Medicine, National University Hospital, Singapore, Division of Gastroenterology and Hepatology, Department of Medicine, National University Hospital, Singapore |
Background and Aim: Gastrointestinal manifestations of the coronavirus disease 2019 (COVID-19) pandemic may mimic irritable bowel syndrome (IBS), and social distancing measures may affect IBS patients negatively. We aimed to study the impact of COVID-19 on respondents with self-reported IBS. Methods: We conducted an anonymized survey from May to June 2020 in 33 countries. Knowledge, attitudes, and practices on personal hygiene and social distancing as well as psychological impact of COVID-19 were assessed. Statistical analysis was performed to determine differences in well-being and compliance to social distancing measures between respondents with and without self-reported IBS. Factors associated with improvement or worsening of IBS symptoms were evaluated. Results: Out of 2704 respondents, 2024 (74.9%) did not have IBS, 305 (11.3%) had self-reported IBS, and 374 (13.8%) did not know what IBS was. Self-reported IBS respondents reported significantly worse emotional, social, and psychological well-being compared with non-IBS respondents and were less compliant to social distancing measures (28.2% vs 35.3%, P = 0.029); 61.6% reported no change, 26.6% reported improvement, and 11.8% reported worsening IBS symptoms. Higher proportion of respondents with no change in IBS symptoms were willing to practice social distancing indefinitely versus those who deteriorated (74.9% vs 51.4%, P = 0.016). In multivariate analysis, willingness to continue social distancing for another 2–3 weeks (vs longer period) was significantly associated with higher odds of worsening IBS. Conclusion: Our study showed that self-reported IBS respondents had worse well-being and compliance to social distancing measures than non-IBS respondents. Future research will focus on occupational stress and dietary changes during COVID-19 that may influence IBS. © 2021 Journal of Gastroenterology and Hepatology Foundation and John Wiley & Sons Australia, Ltd |
COVID-19; IBS; Social distancing |
adult; Article; attitude to health; clinical assessment; clinical evaluation; clinical practice; comparative study; controlled study; coronavirus disease 2019; disease severity; emotion regulation; female; general condition deterioration; health survey; human; irritable colon; major clinical study; male; pandemic; personal hygiene; psychological aspect; psychological well-being; risk factor; self report; social distancing; symptom; clinical trial; cross-sectional study; irritable colon; multicenter study; pandemic; patient compliance; questionnaire; retrospective study; self report; Singapore; Adult; COVID-19; Cross-Sectional Studies; Female; Humans; Irritable Bowel Syndrome; Male; Pandemics; Patient Compliance; Retrospective Studies; SARS-CoV-2; Self Report; Singapore; Surveys and Questio |
John Wiley and Sons Inc |
08159319 |
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33615534 |
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3242 |
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268 |
Findyartini A., Ramani S., McKimm J., Fornari A. |
56543777300;56186462600;26433565200;6701517660; |
Collaborative writing for clinical educators: recommendations from a community of scholars |
2021 |
Clinical Teacher |
18 |
4 |
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330 |
335 |
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https://www.scopus.com/inward/record.uri?eid=2-s2.0-85101865035&doi=10.1111%2ftct.13329&partnerID=40&md5=c416c9d2916367a128e14dacb48e7fc6 |
Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Brigham and Women’s Hospital and Harvard Medical School, Boston, MA, United States; Swansea University Medical School, United Kingdom; Donald and Barbara Zucker SOM at Hofstra/Northwell, Hempstead, NY, United States |
Findyartini, A., Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Ramani, S., Brigham and Women’s Hospital and Harvard Medical School, Boston, MA, United States; McKimm, J., Swansea University Medical School, United Kingdom; Fornari, A., Donald and Barbara Zucker SOM at Hofstra/Northwell, Hempstead, NY, United States |
Clinical educators who wish to engage in scholarship in health professions’ education (HPE), are ideally poised at the intersection of educational theories and their application to educational practice. However, the burden of clinical practice does not often allow the time and space for scholarly writing. Being part of a collaborative writing team, incorporating members with varying levels of expertise, from different health care professions, and at different stages of their career, can provide valuable opportunities for clinicians to contribute to scholarship. Such collaborations can also bridge the gap between scholarship and educational practice in clinical settings. In this paper, we emphasise the benefits of collaborative writing, describe challenges for clinical educators in starting writing projects, and identify potential solutions. We outline a systematic approach to collaborative writing grounded in literature and our own experiences. Three key concepts underpin the provided recommendations: types and standards for scholarship, leadership and followership and communities of practice. Psychological safety, mentoring and a growth mindset are emphasised as integral to successful team projects. Finally, we argue that collaborative writing groups in clinical education can be powerful communities of practice where the overall contribution to the field can be greater than the sum of its parts. © 2021 John Wiley & Sons Ltd and The Association for the Study of Medical Education |
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article; clinical education; human; human experiment; leadership; mentoring; psychological safety; writing; medical education; mentor; Fellowships and Scholarships; Humans; Leadership; Mentors; Writing |
John Wiley and Sons Inc |
17434971 |
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33655649 |
Article |
Q3 |
354 |
13257 |
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269 |
Hoenigl M., Salmanton-García J., Walsh T.J., Nucci M., Neoh C.F., Jenks J.D., Lackner M., Sprute R., Al-Hatmi A.M.S., Bassetti M., Carlesse F., Freiberger T., Koehler P., Lehrnbecher T., Kumar A., Prattes J., Richardson M., Revankar S., Slavin M.A., Stemler J., Spiess B., Taj-Aldeen S.J., Warris A., Woo P.C.Y., Young J.-A.H., Albus K., Arenz D., Arsic-Arsenijevic V., Bouchara J.-P., Chinniah T.R., Chowdhary A., de Hoog G.S., Dimopoulos G., Duarte R.F., Hamal P., Meis J.F., Mfinanga S., Queiroz-Telles F., Patterson T.F., Rahav G., Rogers T.R., Rotstein C., Wahyuningsih R., Seidel D., Cornely O.A. |
23090526000;57016722000;57216999195;7006052823;35269375100;56288564200;36676416300;56381466800;56061758400;57196350860;23024401300;55885407200;55877882300;7003278668;57203775508;55841155700;55520616300;34571895200;7006287667;57212303550;7102753307;6602237737;6603670355;7201801340;7004186640;57226896540;57210309976;6507940363;35427566600;55805374500;7003577085;57226519851;55851942844;7005370707;6602209179;55941779900;6603198848;6701765109;7202308156;35482389900;7202088193;7004535145;6507268400;57191968048;7004206966; |
Global guideline for the diagnosis and management of rare mould infections: an initiative of the European Confederation of Medical Mycology in cooperation with the International Society for Human and Animal Mycology and the American Society for Microbiology |
2021 |
The Lancet. Infectious diseases |
21 |
8 |
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e246 |
e257 |
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29 |
https://www.scopus.com/inward/record.uri?eid=2-s2.0-85101404847&doi=10.1016%2fS1473-3099%2820%2930784-2&partnerID=40&md5=c4d3207ffee3c5129eaa933baa93db58 |
Section of Infectious Diseases and Tropical Medicine, Medical University of Graz, Graz, Austria; Division of Infectious Diseases and Global Public Health, Department of Medicine, University of California San Diego, San Diego, CA, USA; Clinical and Translational Fungal Research Working Group, University of California San Diego, San Diego, CA, USA; European Confederation of Medical Mycology Council, Basel, Switzerland; Faculty of Medicine, University of Cologne, Cologne, Germany; Cologne Excellence Cluster on Cellular Stress Responses in Aging-Associated Diseases, University of Cologne, Cologne, Germany; Department of Medicine, Department of Pediatrics, and Department of Microbiology and Immunology, Weill Cornell Medicine, New York, NY, USA; New York Presbyterian Hospital, Weill Cornell Medical Center, New York, NY, USA; Department of Internal Medicine, Federal University of Rio de Janeiro, Rio de Janeiro, Brazil; Faculty of Pharmacy, Collaborative Drug Discovery Research Group, Pharmaceutical and Life Sciences, Community of Research, Universiti Teknologi MARASelangor, Malaysia; Division of Infectious Diseases and Global Public Health, Department of Medicine, University of California San Diego, San Diego, CA, USA; Clinical and Translational Fungal Research Working Group, University of California San Diego, San Diego, CA, USA; Division of General Internal Medicine, Department of Medicine, University of California San Diego, San Diego, CA, USA; Institute of Hygiene and Medical Microbiology, Department of Hygiene, Medical Microbiology and Publics Health, Medical University Innsbruck, Innsbruck, Austria; Faculty of Medicine, University of Cologne, Cologne, Germany; German Centre for Infection Research, partner site Bonn-Cologne, Cologne, Germany; Department of Microbiology, Natural & Medical Sciences Research Center, University of Nizwa, Nizwa, Oman; Division of Infections Diseases, Department of Health Sciences, IRCCS San Martino Polyclinic Hospital, University of Genoa, Genoa, Italy; Department of Pediatrics, Pediatric Oncology Institute IOP-GRAACC-UNIFESP, Federal Univeristy of São Paulo, São Paulo, Brazil; Centre for Cardiovascular Surgery and Transplantation, Faculty of Medicine, Masaryk University, Brno, Czech Republic; Faculty of Medicine, University of Cologne, Cologne, Germany; Cologne Excellence Cluster on Cellular Stress Responses in Aging-Associated Diseases, University of Cologne, Cologne, Germany; German Centre for Infection Research, partner site Bonn-Cologne, Cologne, Germany; Center for Integrated Oncology Aachen Bonn Cologne Duesseldorf, Cologne, Germany; Division of Pediatric Hematology and Oncology, Hospital for Children and Adolescents, University Hospital, Frankfurt, Germany; Department of Microbiology, Amrita Institute of Medical Sciences and Research Centre, Amrita Vishwa VidyapeethamKochi, India; Section of Infectious Diseases and Tropical Medicine, Medical University of Graz, Graz, Austria; Division of Infection, Immunity and Respiratory Medicine, University of Manchester, Manchester, UK; Mycology Reference Centre Manchester, Manchester University NHS Foundation Trust, Manchester, UK; Division of Infectious Diseases, Wayne State University, MI, Detroit, United States; University of Melbourne, Melbourne, VIC, Australia; National Centre for Infections in Cancer, Peter MacCallum Cancer Centre, Melbourne, VIC, Australia; Department of Hematology and Oncology, Heidelberg University, Mannheim, University Hospital Mannheim, Germany; Department of Laboratory Medicne and Pathology, Hamad Medical Corporation, Doha, Qatar; Medical Research Council Centre for Medical Mycology, University of Exeter, Exeter, United Kingdom; Department of Microbiology, University of Hong Kong, Hong Kong, China; University of Minnesota, MN, Minneapolis, United States; Faculty of Medicine, University of Cologne, Cologne, Germany; Cologne Excellence Cluster on Cellular Stress Responses in Aging-Associated Diseases, University of Cologne, Cologne, Germany; Medical Center Hamburg-Eppendorf, University of Hamburg, Hamburg, Germany; National Reference Laboratory for Medical Mycology, Institute of Microbiology and Immunology, Faculty of Medicine, University of Belgrade, Belgrade, Serbia; European Confederation of Medical Mycology Council, Basel, Switzerland; Host-Pathogen Interaction Study Group, Laboratory of Parasitology and Mycology, Angers University Hospital, Angers University, Angers, France; Department of Microbiology, University of Colombo, Colombo, Sri Lanka; Department of Medical Mycology, Vallabhbhai Patel Chest Institute, University of DelhiDelhi, India; Center of Expertise in Mycology, Radboud University Medical Center-Canisius Wilhelmina Hospital, Nijmegen, Netherlands; Critical Care Department, Attikon University Hospital, National and Kapodistrian University of Athens, Greece; University Hospital Puerta de Hierro MajadahondaMadrid, Spain; Department of Microbiology, Faculty of Medicine and Dentistry, University Hospital Olomouc, Palacky University Olomouc, Olomouc, Czech Republic; European Confederation of Medical Mycology Council, Basel, Switzerland; Department of Medical Microbiology and Infectious Diseases, Radboud University Medical Center-Canisius Wilhelmina Hospital, Nijmegen, Netherlands; Center of Expertise in Mycology, Radboud University Medical Center-Canisius Wilhelmina Hospital, Nijmegen, Netherlands; European Confederation of Medical Mycology Council, Basel, Switzerland; National Institute for Medical Research, Tanzania; Muhimbili University of Health and Allied Sciences, Dar es Salaam, Tanzania; Nelson Mandela African Institution of Science and Technology, Arusha, Tanzania; Department of International Public Health, Liverpool School of Tropical Medicine, Liverpool, UK; Department of Public Health, Clinics Hospital, Federal University of Parana, Curitiba, Brazil; TX, UT Health San Antonio and South Texas Veterans Health Care System, San Antonio, United States; Sheba Medical Center, Sackler School of Medicine, Tel Aviv UniversityTel Aviv, Israel; Department of Clinical Microbiology, Trinity College Dublin, St James's Hospital Campus, Dublin, Ireland; Division of Infectious Diseases, University of Toronto, ON, Toronto, Canada; Department of Parasitology, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Department of Parasitology, Faculty of Medicine, Universitas Kristen Indonesia, Jakarta, Indonesia; Faculty of Medicine, University of Cologne, Cologne, Germany; Cologne Excellence Cluster on Cellular Stress Responses in Aging-Associated Diseases, University of Cologne, Cologne, Germany; German Centre for Infection Research, partner site Bonn-Cologne, Cologne, Germany; Faculty of Medicine, University of Cologne, Cologne, Germany; Cologne Excellence Cluster on Cellular Stress Responses in Aging-Associated Diseases, University of Cologne, Cologne, Germany; Clinical Trials Center Cologne, University of Cologne, Cologne, Germany; German Centre for Infection Research, partner site Bonn-Cologne, Cologne, Germany; European Confederation of Medical Mycology Council, Basel, Switzerland |
Hoenigl, M., Section of Infectious Diseases and Tropical Medicine, Medical University of Graz, Graz, Austria; Division of Infectious Diseases and Global Public Health, Department of Medicine, University of California San Diego, San Diego, CA, USA; Clinical and Translational Fungal Research Working Group, University of California San Diego, San Diego, CA, USA; European Confederation of Medical Mycology Council, Basel, Switzerland; Salmanton-García, J., Faculty of Medicine, University of Cologne, Cologne, Germany; Cologne Excellence Cluster on Cellular Stress Responses in Aging-Associated Diseases, University of Cologne, Cologne, Germany; Walsh, T.J., Department of Medicine, Department of Pediatrics, and Department of Microbiology and Immunology, Weill Cornell Medicine, New York, NY, USA; New York Presbyterian Hospital, Weill Cornell Medical Center, New York, NY, USA; Nucci, M., Department of Internal Medicine, Federal University of Rio de Janeiro, Rio de Janeiro, Brazil; Neoh, C.F., Faculty of Pharmacy, Collaborative Drug Discovery Research Group, Pharmaceutical and Life Sciences, Community of Research, Universiti Teknologi MARASelangor, Malaysia; Jenks, J.D., Division of Infectious Diseases and Global Public Health, Department of Medicine, University of California San Diego, San Diego, CA, USA; Clinical and Translational Fungal Research Working Group, University of California San Diego, San Diego, CA, USA; Division of General Internal Medicine, Department of Medicine, University of California San Diego, San Diego, CA, USA; Lackner, M., Institute of Hygiene and Medical Microbiology, Department of Hygiene, Medical Microbiology and Publics Health, Medical University Innsbruck, Innsbruck, Austria; Sprute, R., Faculty of Medicine, University of Cologne, Cologne, Germany; German Centre for Infection Research, partner site Bonn-Cologne, Cologne, Germany; Al-Hatmi, A.M.S., Department of Microbiology, Natural & Medical Sciences Research Center, University of Nizwa, Nizwa, Oman; Bassetti, M., Division of Infections Diseases, Department of Health Sciences, IRCCS San Martino Polyclinic Hospital, University of Genoa, Genoa, Italy; Carlesse, F., Department of Pediatrics, Pediatric Oncology Institute IOP-GRAACC-UNIFESP, Federal Univeristy of São Paulo, São Paulo, Brazil; Freiberger, T., Centre for Cardiovascular Surgery and Transplantation, Faculty of Medicine, Masaryk University, Brno, Czech Republic; Koehler, P., Faculty of Medicine, University of Cologne, Cologne, Germany; Cologne Excellence Cluster on Cellular Stress Responses in Aging-Associated Diseases, University of Cologne, Cologne, Germany; German Centre for Infection Research, partner site Bonn-Cologne, Cologne, Germany; Center for Integrated Oncology Aachen Bonn Cologne Duesseldorf, Cologne, Germany; Lehrnbecher, T., Division of Pediatric Hematology and Oncology, Hospital for Children and Adolescents, University Hospital, Frankfurt, Germany; Kumar, A., Department of Microbiology, Amrita Institute of Medical Sciences and Research Centre, Amrita Vishwa VidyapeethamKochi, India; Prattes, J., Section of Infectious Diseases and Tropical Medicine, Medical University of Graz, Graz, Austria; Richardson, M., Division of Infection, Immunity and Respiratory Medicine, University of Manchester, Manchester, UK; Mycology Reference Centre Manchester, Manchester University NHS Foundation Trust, Manchester, UK; Revankar, S., Division of Infectious Diseases, Wayne State University, MI, Detroit, United States; Slavin, M.A., University of Melbourne, Melbourne, VIC, Australia; National Centre for Infections in Cancer, Peter MacCallum Cancer Centre, Melbourne, VIC, Australia; Stemler, J., Faculty of Medicine, University of Cologne, Cologne, Germany; German Centre for Infection Research, partner site Bonn-Cologne, Cologne, Germany; Spiess, B., Department of Hematology and Oncology, Heidelberg University, Mannheim, University Hospital Mannheim, Germany; Taj-Aldeen, S.J., Department of Laboratory Medicne and Pathology, Hamad Medical Corporation, Doha, Qatar; Warris, A., Medical Research Council Centre for Medical Mycology, University of Exeter, Exeter, United Kingdom; Woo, P.C.Y., Department of Microbiology, University of Hong Kong, Hong Kong, China; Young, J.-A.H., University of Minnesota, MN, Minneapolis, United States; Albus, K., Faculty of Medicine, University of Cologne, Cologne, Germany; Cologne Excellence Cluster on Cellular Stress Responses in Aging-Associated Diseases, University of Cologne, Cologne, Germany; Arenz, D., Faculty of Medicine, University of Cologne, Cologne, Germany; Cologne Excellence Cluster on Cellular Stress Responses in Aging-Associated Diseases, University of Cologne, Cologne, Germany; Medical Center Hamburg-Eppendorf, University of Hamburg, Hamburg, Germany; Arsic-Arsenijevic, V., National Reference Laboratory for Medical Mycology, Institute of Microbiology and Immunology, Faculty of Medicine, University of Belgrade, Belgrade, Serbia; European Confederation of Medical Mycology Council, Basel, Switzerland; Bouchara, J.-P., Host-Pathogen Interaction Study Group, Laboratory of Parasitology and Mycology, Angers University Hospital, Angers University, Angers, France; Chinniah, T.R., Department of Microbiology, University of Colombo, Colombo, Sri Lanka; Chowdhary, A., Department of Medical Mycology, Vallabhbhai Patel Chest Institute, University of DelhiDelhi, India; de Hoog, G.S., Center of Expertise in Mycology, Radboud University Medical Center-Canisius Wilhelmina Hospital, Nijmegen, Netherlands; Dimopoulos, G., Critical Care Department, Attikon University Hospital, National and Kapodistrian University of Athens, Greece; Duarte, R.F., University Hospital Puerta de Hierro MajadahondaMadrid, Spain; Hamal, P., Department of Microbiology, Faculty of Medicine and Dentistry, University Hospital Olomouc, Palacky University Olomouc, Olomouc, Czech Republic; European Confederation of Medical Mycology Council, Basel, Switzerland; Meis, J.F., Department of Medical Microbiology and Infectious Diseases, Radboud University Medical Center-Canisius Wilhelmina Hospital, Nijmegen, Netherlands; Center of Expertise in Mycology, Radboud University Medical Center-Canisius Wilhelmina Hospital, Nijmegen, Netherlands; European Confederation of Medical Mycology Council, Basel, Switzerland; Mfinanga, S., National Institute for Medical Research, Tanzania; Muhimbili University of Health and Allied Sciences, Dar es Salaam, Tanzania; Nelson Mandela African Institution of Science and Technology, Arusha, Tanzania; Department of International Public Health, Liverpool School of Tropical Medicine, Liverpool, UK; Queiroz-Telles, F., Department of Public Health, Clinics Hospital, Federal University of Parana, Curitiba, Brazil; Patterson, T.F., TX, UT Health San Antonio and South Texas Veterans Health Care System, San Antonio, United States; Rahav, G., Sheba Medical Center, Sackler School of Medicine, Tel Aviv UniversityTel Aviv, Israel; Rogers, T.R., Department of Clinical Microbiology, Trinity College Dublin, St James's Hospital Campus, Dublin, Ireland; Rotstein, C., Division of Infectious Diseases, University of Toronto, ON, Toronto, Canada; Wahyuningsih, R., Department of Parasitology, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Department of Parasitology, Faculty of Medicine, Universitas Kristen Indonesia, Jakarta, Indonesia; Seidel, D., Faculty of Medicine, University of Cologne, Cologne, Germany; Cologne Excellence Cluster on Cellular Stress Responses in Aging-Associated Diseases, University of Cologne, Cologne, Germany; German Centre for Infection Research, partner site Bonn-Cologne, Cologne, Germany; Cornely, O.A., Faculty of Medicine, University of Cologne, Cologne, Germany; Cologne Excellence Cluster on Cellular Stress Responses in Aging-Associated Diseases, University of Cologne, Cologne, Germany; Clinical Trials Center Cologne, University of Cologne, Cologne, Germany; German Centre for Infection Research, partner site Bonn-Cologne, Cologne, Germany; European Confederation of Medical Mycology Council, Basel, Switzerland |
With increasing numbers of patients needing intensive care or who are immunosuppressed, infections caused by moulds other than Aspergillus spp or Mucorales are increasing. Although antifungal prophylaxis has shown effectiveness in preventing many invasive fungal infections, selective pressure has caused an increase of breakthrough infections caused by Fusarium, Lomentospora, and Scedosporium species, as well as by dematiaceous moulds, Rasamsonia, Schizophyllum, Scopulariopsis, Paecilomyces, Penicillium, Talaromyces and Purpureocillium species. Guidance on the complex multidisciplinary management of infections caused by these pathogens has the potential to improve prognosis. Management routes depend on the availability of diagnostic and therapeutic options. The present recommendations are part of the One World-One Guideline initiative to incorporate regional differences in the epidemiology and management of rare mould infections. Experts from 24 countries contributed their knowledge and analysed published evidence on the diagnosis and treatment of rare mould infections. This consensus document intends to provide practical guidance in clinical decision making by engaging physicians and scientists involved in various aspects of clinical management. Moreover, we identify areas of uncertainty and constraints in optimising this management. Copyright © 2021 Elsevier Ltd. All rights reserved. |
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mycosis; animal; diagnosis; disease management; drug effect; drug therapy; fungus; genetics; human; isolation and purification; medical society; microbiology; mycology; physiology; practice guideline; Animals; Disease Management; Fungi; Humans; Mycology; Mycoses; Practice Guidelines as Topic; Societies, Medical |
NLM (Medline) |
14744457 |
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33606997 |
Review |
#N/A |
#N/A |
#N/A |
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270 |
Smith O.J., Wicaksana A., Davidson D., Spratt D., Mosahebi A. |
54881691700;57211445559;55553306500;7004394482;55985666400; |
An evaluation of the bacteriostatic effect of platelet-rich plasma |
2021 |
International Wound Journal |
18 |
4 |
|
448 |
456 |
|
2 |
https://www.scopus.com/inward/record.uri?eid=2-s2.0-85100215304&doi=10.1111%2fiwj.13545&partnerID=40&md5=1f9c16fc126205b4735c175e68af0b2e |
Department of Plastic Surgery, Royal Free Hospital, London, United Kingdom; Division of Surgery and Interventional Science, University College London, London, United Kingdom; Division of Plastic Surgery, Faculty of Medicine Universitas Indonesia/Dr. Cipto Mangunkusumo National Hospital, Jakarta, Indonesia; Microbial Diseases, Eastman Dental Institute, Faculty of Medical Sciences, University College London, London, United Kingdom |
Smith, O.J., Department of Plastic Surgery, Royal Free Hospital, London, United Kingdom, Division of Surgery and Interventional Science, University College London, London, United Kingdom; Wicaksana, A., Division of Surgery and Interventional Science, University College London, London, United Kingdom, Division of Plastic Surgery, Faculty of Medicine Universitas Indonesia/Dr. Cipto Mangunkusumo National Hospital, Jakarta, Indonesia; Davidson, D., Microbial Diseases, Eastman Dental Institute, Faculty of Medical Sciences, University College London, London, United Kingdom; Spratt, D., Microbial Diseases, Eastman Dental Institute, Faculty of Medical Sciences, University College London, London, United Kingdom; Mosahebi, A., Department of Plastic Surgery, Royal Free Hospital, London, United Kingdom, Division of Surgery and Interventional Science, University College London, London, United Kingdom |
Chronic wounds are a considerable health burden with high morbidity and poor rates of healing. Colonisation of chronic wounds by bacteria can be a significant factor in their poor healing rate. These bacteria can develop antibiotic resistance over time and can lead to wound infections, systemic illness, and occasionally amputation. When a large number of micro-organisms colonise wounds, they can lead to biofilm formation, which are self-perpetuating colonies of bacteria closed within an extracellular matrix, which are poorly penetrated by antibiotics. Platelet-rich plasma (PRP) is an autologous blood product rich in growth factors and cytokines that are involved in an inflammatory response. PRP can be injected or applied to a wound as a topical gel, and there is some interest regarding its antimicrobial properties and whether this can improve wound healing. This study aimed to evaluate the in vitro bacteriostatic effect of PRP. PRP was collected from healthy volunteers and processed into two preparations: activated PRP—activated with calcium chloride and ethanol; inactivated PRP. The activity of each preparation against Staphylococcus aureus and Staphylococcus epidermis was evaluated against a control by three experiments: bacterial kill assay to assess planktonic bacterial growth; plate colony assay to assess bacterial colony growth; and colony biofilm assay to assess biofilm growth. Compared with control, both preparations of PRP significantly inhibited growth of planktonic S aureus and S epidermis. Activated PRP reduced planktonic bacterial concentration more than inactivated PRP in both bacteria. Both PRP preparations significantly reduced bacterial colony counts for both bacteria when compared with control; however, there was no difference between the two. There was no difference found between biofilm growth in either PRP against control or against the other preparation. This study demonstrates that PRP does have an inhibitory effect on the growth of common wound pathogens. Activation may be an important factor in increasing the antimicrobial effect of PRP. However, we did not find evidence of an effect against more complex bacterial colonies. © 2021 The Authors. International Wound Journal published by Medicalhelplines.com Inc (3M) and John Wiley & Sons Ltd. |
antimicrobial therapy; chronic wounds; platelet-rich plasma |
alcohol; calcium chloride; antiinfective agent; Article; bacterial count; bacterial growth; bacterial strain; bacteriostatic activity; bacterium colony; biofilm; controlled study; extracellular matrix; in vitro study; nonhuman; Staphylococcus aureus; Staphylococcus epidermidis; thrombocyte activation; thrombocyte rich plasma; human; Staphylococcus infection; wound healing; wound infection; Anti-Bacterial Agents; Humans; Platelet-Rich Plasma; Staphylococcal Infections; Wound Healing; Wound Infection |
John Wiley and Sons Inc |
17424801 |
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33476481 |
Article |
Q1 |
867 |
5385 |
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