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718 |
Umiatin U., Hadisoebroto Dilogo I., Sari P., Kusuma Wijaya S. |
57202292099;57252710600;55776482300;57253327600; |
Histological Analysis of Bone Callus in Delayed Union Model Fracture Healing Stimulated with Pulsed Electromagnetic Fields (PEMF) |
2021 |
Scientifica |
2021 |
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4791172 |
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https://www.scopus.com/inward/record.uri?eid=2-s2.0-85114651138&doi=10.1155%2f2021%2f4791172&partnerID=40&md5=bebbcb4fbf1dcad92f29c04e06fd11bf |
Department of Physics, Faculty of Mathematics and Natural Science, State University of Jakarta, Jakarta, Indonesia; Doctoral Program in Biomedical Science, Faculty of Medicine, University of Indonesia, Jakarta, Indonesia; Department of Orthopedic and Traumatology, Faculty of Medicine, University of Indonesia, Jakarta, Indonesia; Department of Biology, Faculty of Medicine, University of Indonesia, Jakarta, Indonesia; Department of Physics, Faculty of Mathematics and Natural Science, University of Indonesia, Depok, Indonesia |
Umiatin, U., Department of Physics, Faculty of Mathematics and Natural Science, State University of Jakarta, Jakarta, Indonesia, Doctoral Program in Biomedical Science, Faculty of Medicine, University of Indonesia, Jakarta, Indonesia; Hadisoebroto Dilogo, I., Department of Orthopedic and Traumatology, Faculty of Medicine, University of Indonesia, Jakarta, Indonesia; Sari, P., Department of Biology, Faculty of Medicine, University of Indonesia, Jakarta, Indonesia; Kusuma Wijaya, S., Department of Physics, Faculty of Mathematics and Natural Science, University of Indonesia, Depok, Indonesia |
Delayed union and nonunion fractures are clinical challenges for orthopedic surgeons. The development of fracture complications, such as delayed union and nonunion fractures, is still difficult to predict. Various methods are being investigated to improve fracture healing and prevent complications in patients. There are various methods to promote fracture healing, broadly divided into biological, chemical, and physical methods. One of the most widely used physical methods to promote fracture healing is the pulsed electromagnetic field (PEMF). This study aimed to evaluate the healing process of delayed union fracture after being stimulated by PEMF. Twenty-four rats were randomly divided into two groups: the control group (n = 12) and the PEMF group (n = 12). Delayed union fracture was performed on the left femur of all rats. Subsequently, the PEMF group was given PEMF stimulus with a magnetic field intensity of 1.6 mT and a frequency of 50 Hz for 4 hours/day and 7 days/week. The fracture healing process was evaluated on days 5, 10, 18, and 28 based on the bone callus histology using safranin O fast green (SOFG) staining. The results of the histological analysis showed that bone cartilage was higher in the PEMF group than in the control group throughout the observation period. In addition, the PEMF group had less fibrous tissue at the beginning of the healing. This finding indicates PEMF stimulation has an effect on inducing osteogenesis on fracture healing and reducing the risk of delayed union. © 2021 U. Umiatin et al. |
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Hindawi Limited |
2090908X |
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Article |
Q2 |
474 |
10550 |
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721 |
Rahyussalim A.J., Nugroho A., Zufar M.L.L., Fathurrahman I., Kurniawati T. |
55212166100;57211502355;57216349850;57252957500;55213290600; |
Integration of Umbilical Cord Mesenchymal Stem Cell Application in Hydroxyapatite-Based Scaffolds in the Treatment of Vertebral Bone Defect due to Spondylitis Tuberculosis: A Translational Study |
2021 |
Stem Cells International |
2021 |
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9928379 |
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https://www.scopus.com/inward/record.uri?eid=2-s2.0-85114598250&doi=10.1155%2f2021%2f9928379&partnerID=40&md5=4e40b6a1b5d793e962718a6b68d67fa0 |
Department of Orthopaedic and Traumatology, Cipto Mangunkusumo General Hospital, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Stem Cell Medical Technology Integrated Service Unit, Cipto Mangunkusumo General Hospital, Jakarta, Indonesia; Stem Cells and Tissue Engineering Research Cluster, Indonesian Medical Education and Research Institute (IMERI), Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia |
Rahyussalim, A.J., Department of Orthopaedic and Traumatology, Cipto Mangunkusumo General Hospital, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia, Stem Cell Medical Technology Integrated Service Unit, Cipto Mangunkusumo General Hospital, Jakarta, Indonesia, Stem Cells and Tissue Engineering Research Cluster, Indonesian Medical Education and Research Institute (IMERI), Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Nugroho, A., Department of Orthopaedic and Traumatology, Cipto Mangunkusumo General Hospital, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Zufar, M.L.L., Department of Orthopaedic and Traumatology, Cipto Mangunkusumo General Hospital, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Fathurrahman, I., Department of Orthopaedic and Traumatology, Cipto Mangunkusumo General Hospital, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Kurniawati, T., Stem Cell Medical Technology Integrated Service Unit, Cipto Mangunkusumo General Hospital, Jakarta, Indonesia, Stem Cells and Tissue Engineering Research Cluster, Indonesian Medical Education and Research Institute (IMERI), Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia |
Background. Vertebral bone defect represents one of the most commonly found skeletal problems in the spine. Progressive increase of vertebral involvement of skeletal tuberculosis (TB) is reported as the main cause, especially in developed countries. Conventional spinal fusion using bone graft has been associated with donor-site morbidity and complications. We reported the utilization of umbilical cord mesenchymal stem cells (UC-MSCs) combined with hydroxyapatite (HA) based scaffolds in treating vertebral bone defect due to spondylitis tuberculosis. Materials and Methods. Three patients with tuberculous spondylitis in the thoracic, thoracolumbar, or lumbar region with vertebral body collapse of more than 50 percent were included. The patient underwent a 2-stage surgical procedure, consisting of debridement, decompression, and posterior stabilization in the first stage followed by anterior fusion using the lumbotomy approach at the second stage. Twenty million UC-MSCs combined with HA granules in 2 cc of saline were transplanted to fill the vertebral bone defect. Postoperative alkaline phosphatase level, quality of life, and radiological healing were evaluated at one-month, three-month, and six-month follow-up. Results. The initial mean ALP level at one-month follow-up was 48.33±8.50 U/L. This value increased at the three-month follow-up but decreased at the six-month follow-up time, 97±8.19 U/L and 90.33±4.16 U/L, respectively. Bone formation of 50-75% of the defect site with minimal fracture line was found. Increased bone formation comprising 75-100% of the total bone area was reported six months postoperation. A total score of the SF-36 questionnaire showed better progression in all 8 domains during the follow-up with the mean total score at six months of 2912.5±116.67 from all patients. Conclusion. Umbilical cord mesenchymal stem cells combined with hydroxyapatite-based scaffold utilization represent a prospective alternative therapy for bone formation and regeneration of vertebral bone defect due to spondylitis tuberculosis. Further clinical investigations are needed to evaluate this new alternative. © 2021 Ahmad Jabir Rahyussalim et al. |
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alkaline phosphatase; hydroxyapatite; adult; Article; bone defect; bone regeneration; clinical article; female; healing; human; male; ossification; quality of life; spinal cord decompression; spine fusion; spine stabilization; surgical approach; surgical debridement; tuberculous spondylitis; umbilical cord mesenchymal stem cell; vertebral bone defect |
Hindawi Limited |
16879678 |
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Article |
Q2 |
1205 |
3287 |
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726 |
Kim Y., Ahmed E., Ascher N., Danguilan R., Hooi L.S., Hustrini N.M., Kim Y.H., Kute V., Rosete-Liquete R.M.O., Ma M., Mannon R.B., Nakagawa Y., Od-Erdne L., Ramesh V., Rashid H.U., Thangaraju S., Thwin K.T., Vathsala A., West L., Win K.K., Ahn C., Wong G. |
57194114108;57209626753;35394192500;56073507800;6603696990;57200424892;7410196419;36632470600;6507576169;37034386700;7003807110;57236289600;57236003300;57205980938;7102095343;57192114135;57193627441;7003714214;7103226990;57235723800;7201986669;23974794800; |
Meeting Report: First State of the Art Meeting on Gender Disparity in Kidney Transplantation in the Asia-Pacific |
2021 |
Transplantation |
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1888 |
1891 |
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https://www.scopus.com/inward/record.uri?eid=2-s2.0-85113766902&doi=10.1097%2fTP.0000000000003841&partnerID=40&md5=9bfb17e13ffa1ac91810ab03036b4871 |
Department of Internal Medicine, Inje University, Busan Paik Hospital, Busan, South Korea; Department of Nephrology, Sindh Institute of Urology and Transplantation, Karachi, Pakistan; Division of Transplant Surgery, University of California San Francisco, San Francisco, CA, United States; National Kidney and Transplant Institute, Manila, Quezon City, Philippines; Department of Nephrology and Medicine, Sultanah Aminah Hospital, Johor Bahru, Malaysia; Department of Internal Medicine, Faculty of Medicine, Universitas Indonesia, Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Department of Internal Medicine, Inje University, Busan Paik Hospital, Busan, South Korea; Nephrology and Transplantation, Institute of Kidney Diseases and Research Center, Dr. HL Trivedi Institute of Transplantation Sciences (IKDRC-ITS), Gujarat University of Transplantation, Sciences, Ahmedabad, India; National Kidney and Transplant Institute, Philippines; Department of Medicine, Queen Mary Hospital, Hong Kong, Hong Kong; Division of Nephrology, Department of Medicine, University of Nebraska Medical Center, Omaha, NE, United States; Division of Urology, Juntendo University, Tokyo, Japan; Department of Nephrology, First Central Hospital of Mongolia, Organ Transplantation Center, Ulaanbaatar, Mongolia; National Organ and Tissue Transplant Organisation, DGHS, Ministry of Health and Family Welfare, Vardhman Mahavir Medical College, Safdarjung Hospital, New Delhi, India; Department of Nephrology, Kidney Foundation Hospital and Research Institute, Dhaka, Bangladesh; Department of Renal Medicine, Singapore General Hospital, Singapore, Singapore; Department of Renal Medicine, University of Medicine (I), Yangon, Myanmar; Division of Nephrology, National University of Singapore, Singapore, Singapore; Department of Pediatrics, University of Alberta, Edmonton, AB, Canada; Department of Nephrology, Specialty Hospital, Yangon, Myanmar; Division of Nephrology, National Medical Center, Seoul, South Korea; Sydney School of Public Health, University of Sydney, Sydney, NSW, Australia; Centre for Renal and Transplant Research, Westmead Hospital, Sydney, NSW, Australia |
Kim, Y., Department of Internal Medicine, Inje University, Busan Paik Hospital, Busan, South Korea; Ahmed, E., Department of Nephrology, Sindh Institute of Urology and Transplantation, Karachi, Pakistan; Ascher, N., Division of Transplant Surgery, University of California San Francisco, San Francisco, CA, United States; Danguilan, R., National Kidney and Transplant Institute, Manila, Quezon City, Philippines; Hooi, L.S., Department of Nephrology and Medicine, Sultanah Aminah Hospital, Johor Bahru, Malaysia; Hustrini, N.M., Department of Internal Medicine, Faculty of Medicine, Universitas Indonesia, Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Kim, Y.H., Department of Internal Medicine, Inje University, Busan Paik Hospital, Busan, South Korea; Kute, V., Nephrology and Transplantation, Institute of Kidney Diseases and Research Center, Dr. HL Trivedi Institute of Transplantation Sciences (IKDRC-ITS), Gujarat University of Transplantation, Sciences, Ahmedabad, India; Rosete-Liquete, R.M.O., National Kidney and Transplant Institute, Philippines; Ma, M., Department of Medicine, Queen Mary Hospital, Hong Kong, Hong Kong; Mannon, R.B., Division of Nephrology, Department of Medicine, University of Nebraska Medical Center, Omaha, NE, United States; Nakagawa, Y., Division of Urology, Juntendo University, Tokyo, Japan; Od-Erdne, L., Department of Nephrology, First Central Hospital of Mongolia, Organ Transplantation Center, Ulaanbaatar, Mongolia; Ramesh, V., National Organ and Tissue Transplant Organisation, DGHS, Ministry of Health and Family Welfare, Vardhman Mahavir Medical College, Safdarjung Hospital, New Delhi, India; Rashid, H.U., Department of Nephrology, Kidney Foundation Hospital and Research Institute, Dhaka, Bangladesh; Thangaraju, S., Department of Renal Medicine, Singapore General Hospital, Singapore, Singapore; Thwin, K.T., Department of Renal Medicine, University of Medicine (I), Yangon, Myanmar; Vathsala, A., Division of Nephrology, National University of Singapore, Singapore, Singapore; West, L., Department of Pediatrics, University of Alberta, Edmonton, AB, Canada; Win, K.K., Department of Nephrology, Specialty Hospital, Yangon, Myanmar; Ahn, C., Division of Nephrology, National Medical Center, Seoul, South Korea; Wong, G., Sydney School of Public Health, University of Sydney, Sydney, NSW, Australia, Centre for Renal and Transplant Research, Westmead Hospital, Sydney, NSW, Australia |
[No abstract available] |
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Lippincott Williams and Wilkins |
00411337 |
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34416749 |
Article |
Q1 |
1450 |
2398 |
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727 |
Pratomo I.P., Noor D.R., Kusmardi K., Rukmana A., Paramita R.I., Erlina L., Fadilah F., Gayatri A., Fitriani M., Purnomo T.T.H., Ariane A., Heryanto R., Tedjo A. |
57192904477;57214096801;56966625300;35491487100;54882436900;57190181680;56966708600;57204275086;57233517300;57234248500;57210643323;23392757600;57189320451; |
Xanthine Oxidase-Induced Inflammatory Responses in Respiratory Epithelial Cells: A Review in Immunopathology of COVID-19 |
2021 |
International Journal of Inflammation |
2021 |
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1653392 |
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1 |
https://www.scopus.com/inward/record.uri?eid=2-s2.0-85113632856&doi=10.1155%2f2021%2f1653392&partnerID=40&md5=37c46cd8f6ff191ba785fa8abb7052a3 |
Department of Pulmonology and Respiratory Medicine, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; COVID-19 Task Force-Pulmonology and Respiratory Medicine Unit, Universitas Indonesia University Hospital, Universitas Indonesia, Depok, Indonesia; Bioinformatics Core Facilities, Indonesian Medical Education and Research Institute, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Human Cancer Research Center, Indonesian Medical Education and Research Institute, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Department of Pathology Anatomy, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Drug Development Research Cluster, Indonesian Medical Education and Research Institute, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Department of Microbiology, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Department of Medical Chemistry, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Master's Programme in Biomedical Sciences, Faculty of Medicine, Universitas Indonesia, Dki Jakarta, Depok, Indonesia; Department of Pharmacology, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Universitas Indonesia University Hospital, Universitas Indonesia, Depok, Indonesia; Division of Rheumatology, Department of Internal Medicine, Faculty of Medicine, Universitas Indonesia-Dr. Cipto Mangunkusumo Hospital, Indonesia; Department of Chemistry, Faculty of Mathematics and Natural Sciences, Ipb University, Bogor, Indonesia; Tropical Biopharmaca Research Center, Ipb University, Bogor, Indonesia |
Pratomo, I.P., Department of Pulmonology and Respiratory Medicine, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia, COVID-19 Task Force-Pulmonology and Respiratory Medicine Unit, Universitas Indonesia University Hospital, Universitas Indonesia, Depok, Indonesia, Bioinformatics Core Facilities, Indonesian Medical Education and Research Institute, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Noor, D.R., Human Cancer Research Center, Indonesian Medical Education and Research Institute, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Kusmardi, K., Human Cancer Research Center, Indonesian Medical Education and Research Institute, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia, Department of Pathology Anatomy, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia, Drug Development Research Cluster, Indonesian Medical Education and Research Institute, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Rukmana, A., Department of Microbiology, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Paramita, R.I., Bioinformatics Core Facilities, Indonesian Medical Education and Research Institute, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia, Department of Medical Chemistry, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia, Master's Programme in Biomedical Sciences, Faculty of Medicine, Universitas Indonesia, Dki Jakarta, Depok, Indonesia; Erlina, L., Bioinformatics Core Facilities, Indonesian Medical Education and Research Institute, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia, Department of Medical Chemistry, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia, Master's Programme in Biomedical Sciences, Faculty of Medicine, Universitas Indonesia, Dki Jakarta, Depok, Indonesia; Fadilah, F., Bioinformatics Core Facilities, Indonesian Medical Education and Research Institute, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia, Department of Medical Chemistry, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia, Master's Programme in Biomedical Sciences, Faculty of Medicine, Universitas Indonesia, Dki Jakarta, Depok, Indonesia; Gayatri, A., Department of Pharmacology, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Fitriani, M., Universitas Indonesia University Hospital, Universitas Indonesia, Depok, Indonesia; Purnomo, T.T.H., Universitas Indonesia University Hospital, Universitas Indonesia, Depok, Indonesia; Ariane, A., Division of Rheumatology, Department of Internal Medicine, Faculty of Medicine, Universitas Indonesia-Dr. Cipto Mangunkusumo Hospital, Indonesia; Heryanto, R., Department of Chemistry, Faculty of Mathematics and Natural Sciences, Ipb University, Bogor, Indonesia, Tropical Biopharmaca Research Center, Ipb University, Bogor, Indonesia; Tedjo, A., Drug Development Research Cluster, Indonesian Medical Education and Research Institute, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia, Department of Medical Chemistry, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia, Master's Programme in Biomedical Sciences, Faculty of Medicine, Universitas Indonesia, Dki Jakarta, Depok, Indonesia |
Xanthine oxidase (XO) is an enzyme that catalyzes the production of uric acid and superoxide radicals from purine bases: hypoxanthine and xanthine and is also expressed in respiratory epithelial cells. Uric acid, which is also considered a danger associated molecule pattern (DAMP), could trigger a series of inflammatory responses by activating the inflammasome complex path and NF-B within the endothelial cells and by inducing proinflammatory cytokine release. Concurrently, XO also converts the superoxide radicals into hydroxyl radicals that further induce inflammatory responses. These conditions will ultimately sum up a hyperinflammation condition commonly dubbed as cytokine storm syndrome (CSS). The expression of proinflammatory cytokines and neutrophil chemokines may be reduced by XO inhibitor, as observed in human respiratory syncytial virus (HRSV)-infected A549 cells. Our review emphasizes that XO may have an essential role as an anti-inflammation therapy for respiratory viral infection, including coronavirus disease 2019 (COVID-19). © 2021 Irandi Putra Pratomo et al. |
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allopurinol; uric acid; xanthine oxidase; airway epithelium cell; antiinflammatory activity; catalysis; coronavirus disease 2019; cytokine release; enzyme activity; human; hypoxia; immunopathology; inflammation; neutrophil; nonhuman; pathogenesis; protein function; protein targeting; Review; RNA virus infection |
Hindawi Limited |
20908040 |
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Review |
Q2 |
1106 |
3761 |
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739 |
Kamal A.F., Ramang D.S., Prasetyo M. |
56648996700;57195942455;57192905252; |
Thromboembolism in Malignant Musculoskeletal Tumour: A Literature Review |
2021 |
Advances in Orthopedics |
2021 |
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6678167 |
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https://www.scopus.com/inward/record.uri?eid=2-s2.0-85111946705&doi=10.1155%2f2021%2f6678167&partnerID=40&md5=d8f7af261692ce3cb5b68127f841fbe3 |
Department of Orthopaedic and Traumatology, Universitas Indonesia, Cipto Mangunkusumo General Hospital, Jakarta, Indonesia; Department of Radiology, Faculty of Medicine Universitas Indonesia, Cipto Mangunkusumo General Hospital, Jakarta, Indonesia |
Kamal, A.F., Department of Orthopaedic and Traumatology, Universitas Indonesia, Cipto Mangunkusumo General Hospital, Jakarta, Indonesia; Ramang, D.S., Department of Orthopaedic and Traumatology, Universitas Indonesia, Cipto Mangunkusumo General Hospital, Jakarta, Indonesia; Prasetyo, M., Department of Radiology, Faculty of Medicine Universitas Indonesia, Cipto Mangunkusumo General Hospital, Jakarta, Indonesia |
Malignant musculoskeletal tumour may cause considerable burden to general health. The fast growth combined with the tumour characteristics and its invasion capability resulted in the poor prognosis of malignant musculoskeletal tumour. Malignant musculoskeletal tumour may cause significant disability by destroying normal tissue that plays important role in body kinematics. Thromboembolism, including deep vein thrombosis, pulmonary embolism, and other kinds of venous thromboembolism, is one of the most underestimated complications of musculoskeletal tumour. Normally, thrombosis ensues when pathologic factors overcame the body hemostatic regulatory capabilities, which will predispose the body to the formation of thrombus. Venous thromboembolism in musculoskeletal tumour may develop as a result of interaction between the tumour pathologic capabilities and its interaction with normal bodily functions. In this study, we reviewed the burden of musculoskeletal tumour and its complication on global health. Then, the review will focus on the pathologic and clinical aspect of thromboembolism in malignant musculoskeletal tumour, including pathophysiology, diagnosis, and treatment based on recent findings and literature. © 2021 Achmad Fauzi Kamal et al. |
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acetylsalicylic acid; antineoplastic agent; low molecular weight heparin; tranexamic acid; blood examination; bone metastasis; cancer chemotherapy; clinical feature; drug cost; dynamic contrast-enhanced magnetic resonance imaging; echography; global health; human; locomotor system cancer; Medline; pathophysiology; patient compliance; Review; ScienceDirect; Scopus; SpringerLink; systematic review; thromboembolism; thrombosis prevention; tumor thrombus; venous thromboembolism |
Hindawi Limited |
20903464 |
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Review |
Q2 |
681 |
7334 |
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742 |
Paramaiswari W.T., Sidik N.S., Khoeri M.M., Tafroji W., Said W.F., Safari D. |
57221097580;57226416343;55994827400;57118271600;57196217927;23493586700; |
Isolation and Identification of Optochin-Resistant Viridans Group Streptococci from the Sputum Samples of Adult Patients in Jakarta, Indonesia |
2021 |
International Journal of Microbiology |
2021 |
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6646925 |
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https://www.scopus.com/inward/record.uri?eid=2-s2.0-85111490612&doi=10.1155%2f2021%2f6646925&partnerID=40&md5=b022c6984c9b9cf061564ebeaeeb4831 |
Eijkman Institute for Molecular Biology, Jakarta, Indonesia; Department of Biochemistry, Bogor Agricultural University, Bogor, Indonesia; Department of Clinical Pathology, Faculty of Medicine Universitas Indonesia, Cipto Mangunkusumo Hospital, Jakarta, Indonesia |
Paramaiswari, W.T., Eijkman Institute for Molecular Biology, Jakarta, Indonesia; Sidik, N.S., Department of Biochemistry, Bogor Agricultural University, Bogor, Indonesia; Khoeri, M.M., Eijkman Institute for Molecular Biology, Jakarta, Indonesia; Tafroji, W., Eijkman Institute for Molecular Biology, Jakarta, Indonesia; Said, W.F., Department of Clinical Pathology, Faculty of Medicine Universitas Indonesia, Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Safari, D., Eijkman Institute for Molecular Biology, Jakarta, Indonesia |
Aim. To investigate optochin-resistant viridans group streptococci (VGS) strains isolated from the sputum sample of adult patients with different clinical symptoms. Materials and Methods. Optochin-resistant VGS isolates were identified by matrix-assisted laser desorption ionization time of flight mass spectrometry (MALDI-TOF MS). recA sequencing was used to confirm identified isolates at the genus level by MALDI-TOF MS. Finding. We identified 79% of tested isolates (148/187) at the species-level identification using the MALDI-TOF MS tool. We identified that the most common species isolated from sputum specimens were S. oralis (44.9%) followed by S. mitis (25.7%), S. infantis (9.1%), S. parasanguinis (7.5%), S. peroris (3.7%), S. anginosus (2.7%), and S. sanguinis (2.1%). Discussion. The S. oralis strains were majority of optochin-resistant VGS isolates obtained from sputum of adult patients in Jakarta, Indonesia. MALDI-TOF MS showed potential for the rapid identification tool to identify optochin-resistant VGS isolates. Although there were discrepancies in identifying isolates at the genus/species level, the performance could be improved by expanding its database. © 2021 Wisiva Tofriska Paramaiswari et al. |
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Hindawi Limited |
1687918X |
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Article |
Q3 |
696 |
7161 |
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746 |
Schuwirth L., Findyartini A. |
7003825152;56543777300; |
Never waste a good crisis: Resilient health professions education |
2021 |
Asia Pacific Scholar |
6 |
3 |
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1 |
4 |
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https://www.scopus.com/inward/record.uri?eid=2-s2.0-85111073193&doi=10.29060%2fTAPS.2021-6-3%2fEV6N3&partnerID=40&md5=9a31005ce32498af7be04ec902845ab8 |
Prideaux Centre for Research in Health Professions Education, College of Medicine and Public Health, Flinders University, Australia; Department of Medical Education, Faculty of Medicine, Universitas Indonesia, Indonesia |
Schuwirth, L., Prideaux Centre for Research in Health Professions Education, College of Medicine and Public Health, Flinders University, Australia; Findyartini, A., Department of Medical Education, Faculty of Medicine, Universitas Indonesia, Indonesia |
[No abstract available] |
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National University of Singapore, Faculty of Law |
24249335 |
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Editorial |
#N/A |
#N/A |
#N/A |
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751 |
Soetikno V. |
36769252100; |
The importance of registry for systematic review and clinical trial |
2021 |
Medical Journal of Indonesia |
30 |
2 |
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87 |
88 |
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https://www.scopus.com/inward/record.uri?eid=2-s2.0-85110707318&doi=10.13181%2fmji.ed.215620&partnerID=40&md5=f191fe1a910178e15d2b72bb4de9df1c |
Medical Journal of Indonesia, Department of Pharmacology and Therapeutics, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia |
Soetikno, V., Medical Journal of Indonesia, Department of Pharmacology and Therapeutics, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia |
[No abstract available] |
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placebo; Cochrane Library; controlled study; data extraction; Editorial; erectile dysfunction; evaluation study; health care policy; human; medical literature; Medline; mesenchymal stem cell; meta analysis; outcome assessment; Preferred Reporting Items for Systematic Reviews and Meta-Analyses; publication; publication bias; questionnaire; randomized controlled trial; register; review; risk assessment; search engine; systematic review |
Faculty of Medicine, Universitas Indonesia |
08531773 |
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Editorial |
Q4 |
164 |
21905 |
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761 |
Lesmana C.R.A., Paramitha M.S., Gani R.A. |
8977683000;57212562901;23495930300; |
The Role of Interventional Endoscopic Ultrasound in Liver Diseases: What Have We Learnt? |
2021 |
Canadian Journal of Gastroenterology and Hepatology |
2021 |
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9948979 |
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1 |
https://www.scopus.com/inward/record.uri?eid=2-s2.0-85110213187&doi=10.1155%2f2021%2f9948979&partnerID=40&md5=a038d06d78df9e699aa4a27ead88d0bb |
Department of Internal Medicine, Hepatobiliary Division, Dr. Cipto Mangunkusumo National General Hospital, Universitas Indonesia, Jakarta, Indonesia; Digestive Disease and GI Oncology Center, Medistra Hospital, Jakarta, Indonesia |
Lesmana, C.R.A., Department of Internal Medicine, Hepatobiliary Division, Dr. Cipto Mangunkusumo National General Hospital, Universitas Indonesia, Jakarta, Indonesia, Digestive Disease and GI Oncology Center, Medistra Hospital, Jakarta, Indonesia; Paramitha, M.S., Department of Internal Medicine, Hepatobiliary Division, Dr. Cipto Mangunkusumo National General Hospital, Universitas Indonesia, Jakarta, Indonesia; Gani, R.A., Department of Internal Medicine, Hepatobiliary Division, Dr. Cipto Mangunkusumo National General Hospital, Universitas Indonesia, Jakarta, Indonesia |
Chronic liver disease (CLD) is still a major problem, where the disease progression will lead to liver cirrhosis (LC) or hepatocellular carcinoma (HCC). Portal hypertension (PH) management and loco-regional therapy for HCC have become the cornerstones in advanced liver disease management. Recently, there are studies looking at the potential role of interventional endoscopic ultrasound (EUS) in liver diseases. EUS may be useful in vascular changes of the digestive wall evaluation, performing dynamic assessment of hemodynamic changes, predicting variceal bleeding and rebleeding risk, and assessing the pharmacological effects. In PH management, EUS-guided vascular therapy - which revolves around glue injection, endovascular coil placement/embolization, and combination of both - has shown promising results. As a diagnostic modality for liver cancer, the implementation of EUS in liver diseases is currently not only limited to liver biopsy (EUS-LB) but also in shear-wave elastography (SWE) and portal pressure gradient measurement, as well as portal vein sampling. The application of EUS-guided radiofrequency ablation (EUS-RFA) and tumor injection can also overcome the limitations shown by both modalities without EUS. Nevertheless, establishing EUS as a firm diagnostic and therapeutic modality is still challenging since the performance of interventional EUS requires high expertise and adequate facilities. © 2021 Cosmas Rinaldi A. Lesmana et al. |
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azygos vein; brachytherapy; chronic liver disease; contrast-enhanced ultrasound; cryotherapy; Doppler flowmetry; elastography; endoscopic ultrasonography; gastrointestinal hemorrhage; human; liver abscess; liver biopsy; liver cirrhosis; liver injury; liver metastasis; nonhuman; paracentesis; peritonitis; portal vein blood pressure; predictive value; radiation exposure; regional perfusion; Review; risk assessment; sclerotherapy; sensitivity and specificity; shear wave elastography; splanchnic blood flow; diagnostic imaging; endoscopic ultrasonography; esophagus varices; interventional ultrasonography; liver cell carcinoma; liver tumor; tumor recurrence; Carcinoma, Hepatocellular; Endosonography; Esophageal and Gastric Varices; Gastrointestinal Hemorrhage; Humans; Liver Neoplasms; Neoplasm R |
Hindawi Limited |
22912789 |
|
34258255 |
Review |
Q2 |
921 |
4950 |
|
|
|
766 |
Dharma S., Dakota I., Andriantoro H., Firdaus I., Gunawan Limadhy I., Van De Werf F. |
55101301700;55796663700;55037171500;55796864700;57225219360;36048879600; |
Trends in reperfusion therapy for acute ST-segment elevation myocardial infarction in an academic percutaneous coronary intervention center in the metropolitan area of a developing country: Insights from the Jakarta Acute Coronary Syndrome registry |
2021 |
Coronary Artery Disease |
|
|
|
466 |
467 |
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https://www.scopus.com/inward/record.uri?eid=2-s2.0-85109587625&doi=10.1097%2fMCA.0000000000000939&partnerID=40&md5=a4f6e1151d84a687c4d99a6b1f8480c6 |
Department of Cardiology and Vascular Medicine, Faculty of Medicine, University of Indonesia, Indonesian Cardiovascular Research Center, National Cardiovascular Center Harapan Kita, Jl S Parman Kav 87, Slipi, Jakarta Barat, Jakarta, 11420, Indonesia; Department of Cardiology and Vascular Medicine, Faculty of Medicine, University of Indonesia, National Cardiovascular Center Harapan Kita, Indonesia; Indonesian Cardiovascular Research Center, National Cardiovascular Center Harapan Kita, Jakarta, Indonesia; Department of Cardiovascular Sciences, KU Leuven, Leuven, Belgium |
Dharma, S., Department of Cardiology and Vascular Medicine, Faculty of Medicine, University of Indonesia, Indonesian Cardiovascular Research Center, National Cardiovascular Center Harapan Kita, Jl S Parman Kav 87, Slipi, Jakarta Barat, Jakarta, 11420, Indonesia; Dakota, I., Department of Cardiology and Vascular Medicine, Faculty of Medicine, University of Indonesia, National Cardiovascular Center Harapan Kita, Indonesia; Andriantoro, H., Department of Cardiology and Vascular Medicine, Faculty of Medicine, University of Indonesia, National Cardiovascular Center Harapan Kita, Indonesia; Firdaus, I., Department of Cardiology and Vascular Medicine, Faculty of Medicine, University of Indonesia, National Cardiovascular Center Harapan Kita, Indonesia; Gunawan Limadhy, I., Indonesian Cardiovascular Research Center, National Cardiovascular Center Harapan Kita, Jakarta, Indonesia; Van De Werf, F., Department of Cardiovascular Sciences, KU Leuven, Leuven, Belgium |
[No abstract available] |
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adverse event; causality; epidemiology; female; fibrinolytic therapy; heart muscle reperfusion; hospital mortality; human; Indonesia; male; middle aged; mortality; organization and management; percutaneous coronary intervention; preventive health service; procedures; register; ST segment elevation myocardial infarction; time to treatment; total quality management; Causality; Female; Hospital Mortality; Humans; Indonesia; Male; Middle Aged; Myocardial Reperfusion; Percutaneous Coronary Intervention; Preventive Health Services; Quality Improvement; Registries; ST Elevation Myocardial Infarction; Thrombolytic Therapy; Time-to-Treatment |
Lippincott Williams and Wilkins |
09546928 |
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32804781 |
Article |
Q3 |
504 |
10001 |
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