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268 |
Findyartini A., Ramani S., McKimm J., Fornari A. |
56543777300;56186462600;26433565200;6701517660; |
Collaborative writing for clinical educators: recommendations from a community of scholars |
2021 |
Clinical Teacher |
18 |
4 |
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330 |
335 |
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https://www.scopus.com/inward/record.uri?eid=2-s2.0-85101865035&doi=10.1111%2ftct.13329&partnerID=40&md5=c416c9d2916367a128e14dacb48e7fc6 |
Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Brigham and Women’s Hospital and Harvard Medical School, Boston, MA, United States; Swansea University Medical School, United Kingdom; Donald and Barbara Zucker SOM at Hofstra/Northwell, Hempstead, NY, United States |
Findyartini, A., Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Ramani, S., Brigham and Women’s Hospital and Harvard Medical School, Boston, MA, United States; McKimm, J., Swansea University Medical School, United Kingdom; Fornari, A., Donald and Barbara Zucker SOM at Hofstra/Northwell, Hempstead, NY, United States |
Clinical educators who wish to engage in scholarship in health professions’ education (HPE), are ideally poised at the intersection of educational theories and their application to educational practice. However, the burden of clinical practice does not often allow the time and space for scholarly writing. Being part of a collaborative writing team, incorporating members with varying levels of expertise, from different health care professions, and at different stages of their career, can provide valuable opportunities for clinicians to contribute to scholarship. Such collaborations can also bridge the gap between scholarship and educational practice in clinical settings. In this paper, we emphasise the benefits of collaborative writing, describe challenges for clinical educators in starting writing projects, and identify potential solutions. We outline a systematic approach to collaborative writing grounded in literature and our own experiences. Three key concepts underpin the provided recommendations: types and standards for scholarship, leadership and followership and communities of practice. Psychological safety, mentoring and a growth mindset are emphasised as integral to successful team projects. Finally, we argue that collaborative writing groups in clinical education can be powerful communities of practice where the overall contribution to the field can be greater than the sum of its parts. © 2021 John Wiley & Sons Ltd and The Association for the Study of Medical Education |
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article; clinical education; human; human experiment; leadership; mentoring; psychological safety; writing; medical education; mentor; Fellowships and Scholarships; Humans; Leadership; Mentors; Writing |
John Wiley and Sons Inc |
17434971 |
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33655649 |
Article |
Q3 |
354 |
13257 |
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269 |
Hoenigl M., Salmanton-García J., Walsh T.J., Nucci M., Neoh C.F., Jenks J.D., Lackner M., Sprute R., Al-Hatmi A.M.S., Bassetti M., Carlesse F., Freiberger T., Koehler P., Lehrnbecher T., Kumar A., Prattes J., Richardson M., Revankar S., Slavin M.A., Stemler J., Spiess B., Taj-Aldeen S.J., Warris A., Woo P.C.Y., Young J.-A.H., Albus K., Arenz D., Arsic-Arsenijevic V., Bouchara J.-P., Chinniah T.R., Chowdhary A., de Hoog G.S., Dimopoulos G., Duarte R.F., Hamal P., Meis J.F., Mfinanga S., Queiroz-Telles F., Patterson T.F., Rahav G., Rogers T.R., Rotstein C., Wahyuningsih R., Seidel D., Cornely O.A. |
23090526000;57016722000;57216999195;7006052823;35269375100;56288564200;36676416300;56381466800;56061758400;57196350860;23024401300;55885407200;55877882300;7003278668;57203775508;55841155700;55520616300;34571895200;7006287667;57212303550;7102753307;6602237737;6603670355;7201801340;7004186640;57226896540;57210309976;6507940363;35427566600;55805374500;7003577085;57226519851;55851942844;7005370707;6602209179;55941779900;6603198848;6701765109;7202308156;35482389900;7202088193;7004535145;6507268400;57191968048;7004206966; |
Global guideline for the diagnosis and management of rare mould infections: an initiative of the European Confederation of Medical Mycology in cooperation with the International Society for Human and Animal Mycology and the American Society for Microbiology |
2021 |
The Lancet. Infectious diseases |
21 |
8 |
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e246 |
e257 |
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29 |
https://www.scopus.com/inward/record.uri?eid=2-s2.0-85101404847&doi=10.1016%2fS1473-3099%2820%2930784-2&partnerID=40&md5=c4d3207ffee3c5129eaa933baa93db58 |
Section of Infectious Diseases and Tropical Medicine, Medical University of Graz, Graz, Austria; Division of Infectious Diseases and Global Public Health, Department of Medicine, University of California San Diego, San Diego, CA, USA; Clinical and Translational Fungal Research Working Group, University of California San Diego, San Diego, CA, USA; European Confederation of Medical Mycology Council, Basel, Switzerland; Faculty of Medicine, University of Cologne, Cologne, Germany; Cologne Excellence Cluster on Cellular Stress Responses in Aging-Associated Diseases, University of Cologne, Cologne, Germany; Department of Medicine, Department of Pediatrics, and Department of Microbiology and Immunology, Weill Cornell Medicine, New York, NY, USA; New York Presbyterian Hospital, Weill Cornell Medical Center, New York, NY, USA; Department of Internal Medicine, Federal University of Rio de Janeiro, Rio de Janeiro, Brazil; Faculty of Pharmacy, Collaborative Drug Discovery Research Group, Pharmaceutical and Life Sciences, Community of Research, Universiti Teknologi MARASelangor, Malaysia; Division of Infectious Diseases and Global Public Health, Department of Medicine, University of California San Diego, San Diego, CA, USA; Clinical and Translational Fungal Research Working Group, University of California San Diego, San Diego, CA, USA; Division of General Internal Medicine, Department of Medicine, University of California San Diego, San Diego, CA, USA; Institute of Hygiene and Medical Microbiology, Department of Hygiene, Medical Microbiology and Publics Health, Medical University Innsbruck, Innsbruck, Austria; Faculty of Medicine, University of Cologne, Cologne, Germany; German Centre for Infection Research, partner site Bonn-Cologne, Cologne, Germany; Department of Microbiology, Natural & Medical Sciences Research Center, University of Nizwa, Nizwa, Oman; Division of Infections Diseases, Department of Health Sciences, IRCCS San Martino Polyclinic Hospital, University of Genoa, Genoa, Italy; Department of Pediatrics, Pediatric Oncology Institute IOP-GRAACC-UNIFESP, Federal Univeristy of São Paulo, São Paulo, Brazil; Centre for Cardiovascular Surgery and Transplantation, Faculty of Medicine, Masaryk University, Brno, Czech Republic; Faculty of Medicine, University of Cologne, Cologne, Germany; Cologne Excellence Cluster on Cellular Stress Responses in Aging-Associated Diseases, University of Cologne, Cologne, Germany; German Centre for Infection Research, partner site Bonn-Cologne, Cologne, Germany; Center for Integrated Oncology Aachen Bonn Cologne Duesseldorf, Cologne, Germany; Division of Pediatric Hematology and Oncology, Hospital for Children and Adolescents, University Hospital, Frankfurt, Germany; Department of Microbiology, Amrita Institute of Medical Sciences and Research Centre, Amrita Vishwa VidyapeethamKochi, India; Section of Infectious Diseases and Tropical Medicine, Medical University of Graz, Graz, Austria; Division of Infection, Immunity and Respiratory Medicine, University of Manchester, Manchester, UK; Mycology Reference Centre Manchester, Manchester University NHS Foundation Trust, Manchester, UK; Division of Infectious Diseases, Wayne State University, MI, Detroit, United States; University of Melbourne, Melbourne, VIC, Australia; National Centre for Infections in Cancer, Peter MacCallum Cancer Centre, Melbourne, VIC, Australia; Department of Hematology and Oncology, Heidelberg University, Mannheim, University Hospital Mannheim, Germany; Department of Laboratory Medicne and Pathology, Hamad Medical Corporation, Doha, Qatar; Medical Research Council Centre for Medical Mycology, University of Exeter, Exeter, United Kingdom; Department of Microbiology, University of Hong Kong, Hong Kong, China; University of Minnesota, MN, Minneapolis, United States; Faculty of Medicine, University of Cologne, Cologne, Germany; Cologne Excellence Cluster on Cellular Stress Responses in Aging-Associated Diseases, University of Cologne, Cologne, Germany; Medical Center Hamburg-Eppendorf, University of Hamburg, Hamburg, Germany; National Reference Laboratory for Medical Mycology, Institute of Microbiology and Immunology, Faculty of Medicine, University of Belgrade, Belgrade, Serbia; European Confederation of Medical Mycology Council, Basel, Switzerland; Host-Pathogen Interaction Study Group, Laboratory of Parasitology and Mycology, Angers University Hospital, Angers University, Angers, France; Department of Microbiology, University of Colombo, Colombo, Sri Lanka; Department of Medical Mycology, Vallabhbhai Patel Chest Institute, University of DelhiDelhi, India; Center of Expertise in Mycology, Radboud University Medical Center-Canisius Wilhelmina Hospital, Nijmegen, Netherlands; Critical Care Department, Attikon University Hospital, National and Kapodistrian University of Athens, Greece; University Hospital Puerta de Hierro MajadahondaMadrid, Spain; Department of Microbiology, Faculty of Medicine and Dentistry, University Hospital Olomouc, Palacky University Olomouc, Olomouc, Czech Republic; European Confederation of Medical Mycology Council, Basel, Switzerland; Department of Medical Microbiology and Infectious Diseases, Radboud University Medical Center-Canisius Wilhelmina Hospital, Nijmegen, Netherlands; Center of Expertise in Mycology, Radboud University Medical Center-Canisius Wilhelmina Hospital, Nijmegen, Netherlands; European Confederation of Medical Mycology Council, Basel, Switzerland; National Institute for Medical Research, Tanzania; Muhimbili University of Health and Allied Sciences, Dar es Salaam, Tanzania; Nelson Mandela African Institution of Science and Technology, Arusha, Tanzania; Department of International Public Health, Liverpool School of Tropical Medicine, Liverpool, UK; Department of Public Health, Clinics Hospital, Federal University of Parana, Curitiba, Brazil; TX, UT Health San Antonio and South Texas Veterans Health Care System, San Antonio, United States; Sheba Medical Center, Sackler School of Medicine, Tel Aviv UniversityTel Aviv, Israel; Department of Clinical Microbiology, Trinity College Dublin, St James's Hospital Campus, Dublin, Ireland; Division of Infectious Diseases, University of Toronto, ON, Toronto, Canada; Department of Parasitology, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Department of Parasitology, Faculty of Medicine, Universitas Kristen Indonesia, Jakarta, Indonesia; Faculty of Medicine, University of Cologne, Cologne, Germany; Cologne Excellence Cluster on Cellular Stress Responses in Aging-Associated Diseases, University of Cologne, Cologne, Germany; German Centre for Infection Research, partner site Bonn-Cologne, Cologne, Germany; Faculty of Medicine, University of Cologne, Cologne, Germany; Cologne Excellence Cluster on Cellular Stress Responses in Aging-Associated Diseases, University of Cologne, Cologne, Germany; Clinical Trials Center Cologne, University of Cologne, Cologne, Germany; German Centre for Infection Research, partner site Bonn-Cologne, Cologne, Germany; European Confederation of Medical Mycology Council, Basel, Switzerland |
Hoenigl, M., Section of Infectious Diseases and Tropical Medicine, Medical University of Graz, Graz, Austria; Division of Infectious Diseases and Global Public Health, Department of Medicine, University of California San Diego, San Diego, CA, USA; Clinical and Translational Fungal Research Working Group, University of California San Diego, San Diego, CA, USA; European Confederation of Medical Mycology Council, Basel, Switzerland; Salmanton-García, J., Faculty of Medicine, University of Cologne, Cologne, Germany; Cologne Excellence Cluster on Cellular Stress Responses in Aging-Associated Diseases, University of Cologne, Cologne, Germany; Walsh, T.J., Department of Medicine, Department of Pediatrics, and Department of Microbiology and Immunology, Weill Cornell Medicine, New York, NY, USA; New York Presbyterian Hospital, Weill Cornell Medical Center, New York, NY, USA; Nucci, M., Department of Internal Medicine, Federal University of Rio de Janeiro, Rio de Janeiro, Brazil; Neoh, C.F., Faculty of Pharmacy, Collaborative Drug Discovery Research Group, Pharmaceutical and Life Sciences, Community of Research, Universiti Teknologi MARASelangor, Malaysia; Jenks, J.D., Division of Infectious Diseases and Global Public Health, Department of Medicine, University of California San Diego, San Diego, CA, USA; Clinical and Translational Fungal Research Working Group, University of California San Diego, San Diego, CA, USA; Division of General Internal Medicine, Department of Medicine, University of California San Diego, San Diego, CA, USA; Lackner, M., Institute of Hygiene and Medical Microbiology, Department of Hygiene, Medical Microbiology and Publics Health, Medical University Innsbruck, Innsbruck, Austria; Sprute, R., Faculty of Medicine, University of Cologne, Cologne, Germany; German Centre for Infection Research, partner site Bonn-Cologne, Cologne, Germany; Al-Hatmi, A.M.S., Department of Microbiology, Natural & Medical Sciences Research Center, University of Nizwa, Nizwa, Oman; Bassetti, M., Division of Infections Diseases, Department of Health Sciences, IRCCS San Martino Polyclinic Hospital, University of Genoa, Genoa, Italy; Carlesse, F., Department of Pediatrics, Pediatric Oncology Institute IOP-GRAACC-UNIFESP, Federal Univeristy of São Paulo, São Paulo, Brazil; Freiberger, T., Centre for Cardiovascular Surgery and Transplantation, Faculty of Medicine, Masaryk University, Brno, Czech Republic; Koehler, P., Faculty of Medicine, University of Cologne, Cologne, Germany; Cologne Excellence Cluster on Cellular Stress Responses in Aging-Associated Diseases, University of Cologne, Cologne, Germany; German Centre for Infection Research, partner site Bonn-Cologne, Cologne, Germany; Center for Integrated Oncology Aachen Bonn Cologne Duesseldorf, Cologne, Germany; Lehrnbecher, T., Division of Pediatric Hematology and Oncology, Hospital for Children and Adolescents, University Hospital, Frankfurt, Germany; Kumar, A., Department of Microbiology, Amrita Institute of Medical Sciences and Research Centre, Amrita Vishwa VidyapeethamKochi, India; Prattes, J., Section of Infectious Diseases and Tropical Medicine, Medical University of Graz, Graz, Austria; Richardson, M., Division of Infection, Immunity and Respiratory Medicine, University of Manchester, Manchester, UK; Mycology Reference Centre Manchester, Manchester University NHS Foundation Trust, Manchester, UK; Revankar, S., Division of Infectious Diseases, Wayne State University, MI, Detroit, United States; Slavin, M.A., University of Melbourne, Melbourne, VIC, Australia; National Centre for Infections in Cancer, Peter MacCallum Cancer Centre, Melbourne, VIC, Australia; Stemler, J., Faculty of Medicine, University of Cologne, Cologne, Germany; German Centre for Infection Research, partner site Bonn-Cologne, Cologne, Germany; Spiess, B., Department of Hematology and Oncology, Heidelberg University, Mannheim, University Hospital Mannheim, Germany; Taj-Aldeen, S.J., Department of Laboratory Medicne and Pathology, Hamad Medical Corporation, Doha, Qatar; Warris, A., Medical Research Council Centre for Medical Mycology, University of Exeter, Exeter, United Kingdom; Woo, P.C.Y., Department of Microbiology, University of Hong Kong, Hong Kong, China; Young, J.-A.H., University of Minnesota, MN, Minneapolis, United States; Albus, K., Faculty of Medicine, University of Cologne, Cologne, Germany; Cologne Excellence Cluster on Cellular Stress Responses in Aging-Associated Diseases, University of Cologne, Cologne, Germany; Arenz, D., Faculty of Medicine, University of Cologne, Cologne, Germany; Cologne Excellence Cluster on Cellular Stress Responses in Aging-Associated Diseases, University of Cologne, Cologne, Germany; Medical Center Hamburg-Eppendorf, University of Hamburg, Hamburg, Germany; Arsic-Arsenijevic, V., National Reference Laboratory for Medical Mycology, Institute of Microbiology and Immunology, Faculty of Medicine, University of Belgrade, Belgrade, Serbia; European Confederation of Medical Mycology Council, Basel, Switzerland; Bouchara, J.-P., Host-Pathogen Interaction Study Group, Laboratory of Parasitology and Mycology, Angers University Hospital, Angers University, Angers, France; Chinniah, T.R., Department of Microbiology, University of Colombo, Colombo, Sri Lanka; Chowdhary, A., Department of Medical Mycology, Vallabhbhai Patel Chest Institute, University of DelhiDelhi, India; de Hoog, G.S., Center of Expertise in Mycology, Radboud University Medical Center-Canisius Wilhelmina Hospital, Nijmegen, Netherlands; Dimopoulos, G., Critical Care Department, Attikon University Hospital, National and Kapodistrian University of Athens, Greece; Duarte, R.F., University Hospital Puerta de Hierro MajadahondaMadrid, Spain; Hamal, P., Department of Microbiology, Faculty of Medicine and Dentistry, University Hospital Olomouc, Palacky University Olomouc, Olomouc, Czech Republic; European Confederation of Medical Mycology Council, Basel, Switzerland; Meis, J.F., Department of Medical Microbiology and Infectious Diseases, Radboud University Medical Center-Canisius Wilhelmina Hospital, Nijmegen, Netherlands; Center of Expertise in Mycology, Radboud University Medical Center-Canisius Wilhelmina Hospital, Nijmegen, Netherlands; European Confederation of Medical Mycology Council, Basel, Switzerland; Mfinanga, S., National Institute for Medical Research, Tanzania; Muhimbili University of Health and Allied Sciences, Dar es Salaam, Tanzania; Nelson Mandela African Institution of Science and Technology, Arusha, Tanzania; Department of International Public Health, Liverpool School of Tropical Medicine, Liverpool, UK; Queiroz-Telles, F., Department of Public Health, Clinics Hospital, Federal University of Parana, Curitiba, Brazil; Patterson, T.F., TX, UT Health San Antonio and South Texas Veterans Health Care System, San Antonio, United States; Rahav, G., Sheba Medical Center, Sackler School of Medicine, Tel Aviv UniversityTel Aviv, Israel; Rogers, T.R., Department of Clinical Microbiology, Trinity College Dublin, St James's Hospital Campus, Dublin, Ireland; Rotstein, C., Division of Infectious Diseases, University of Toronto, ON, Toronto, Canada; Wahyuningsih, R., Department of Parasitology, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Department of Parasitology, Faculty of Medicine, Universitas Kristen Indonesia, Jakarta, Indonesia; Seidel, D., Faculty of Medicine, University of Cologne, Cologne, Germany; Cologne Excellence Cluster on Cellular Stress Responses in Aging-Associated Diseases, University of Cologne, Cologne, Germany; German Centre for Infection Research, partner site Bonn-Cologne, Cologne, Germany; Cornely, O.A., Faculty of Medicine, University of Cologne, Cologne, Germany; Cologne Excellence Cluster on Cellular Stress Responses in Aging-Associated Diseases, University of Cologne, Cologne, Germany; Clinical Trials Center Cologne, University of Cologne, Cologne, Germany; German Centre for Infection Research, partner site Bonn-Cologne, Cologne, Germany; European Confederation of Medical Mycology Council, Basel, Switzerland |
With increasing numbers of patients needing intensive care or who are immunosuppressed, infections caused by moulds other than Aspergillus spp or Mucorales are increasing. Although antifungal prophylaxis has shown effectiveness in preventing many invasive fungal infections, selective pressure has caused an increase of breakthrough infections caused by Fusarium, Lomentospora, and Scedosporium species, as well as by dematiaceous moulds, Rasamsonia, Schizophyllum, Scopulariopsis, Paecilomyces, Penicillium, Talaromyces and Purpureocillium species. Guidance on the complex multidisciplinary management of infections caused by these pathogens has the potential to improve prognosis. Management routes depend on the availability of diagnostic and therapeutic options. The present recommendations are part of the One World-One Guideline initiative to incorporate regional differences in the epidemiology and management of rare mould infections. Experts from 24 countries contributed their knowledge and analysed published evidence on the diagnosis and treatment of rare mould infections. This consensus document intends to provide practical guidance in clinical decision making by engaging physicians and scientists involved in various aspects of clinical management. Moreover, we identify areas of uncertainty and constraints in optimising this management. Copyright © 2021 Elsevier Ltd. All rights reserved. |
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mycosis; animal; diagnosis; disease management; drug effect; drug therapy; fungus; genetics; human; isolation and purification; medical society; microbiology; mycology; physiology; practice guideline; Animals; Disease Management; Fungi; Humans; Mycology; Mycoses; Practice Guidelines as Topic; Societies, Medical |
NLM (Medline) |
14744457 |
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33606997 |
Review |
#N/A |
#N/A |
#N/A |
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280 |
Pradita L.W., Kamilla D.N., Soedarsono N., Yunaini L., Auerkari E.I. |
57226576844;57226575340;14049161500;57192911515;10139113000; |
Intron 4 VNTR A/B polymorphism of endothelial nitric oxide synthase gene in periodontitis |
2021 |
Journal of Physics: Conference Series |
1943 |
1 |
012087 |
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https://www.scopus.com/inward/record.uri?eid=2-s2.0-85112023901&doi=10.1088%2f1742-6596%2f1943%2f1%2f012087&partnerID=40&md5=a0fb2d74d58911990f7e8f70aaf919b9 |
Department of Oral Biology, Faculty of Dentistry, University of Indonesia, Jakarta, Indonesia; Department of Medical Biology, Faculty of Medicine, University of Indonesia, Jakarta, Indonesia |
Pradita, L.W., Department of Oral Biology, Faculty of Dentistry, University of Indonesia, Jakarta, Indonesia; Kamilla, D.N., Department of Oral Biology, Faculty of Dentistry, University of Indonesia, Jakarta, Indonesia; Soedarsono, N., Department of Oral Biology, Faculty of Dentistry, University of Indonesia, Jakarta, Indonesia; Yunaini, L., Department of Medical Biology, Faculty of Medicine, University of Indonesia, Jakarta, Indonesia; Auerkari, E.I., Department of Oral Biology, Faculty of Dentistry, University of Indonesia, Jakarta, Indonesia |
Nitric Oxide (NO) is an important mediator in the inflammatory and immune systems. The eNOS gene is one of the three isoforms of Nitric Oxide Synthase (NOS), which is responsible for synthesizing NO. Periodontitis is an inflammatory disease in periodontal tissue with genetic involvement. Polymorphism in eNOS gene changes the functional aspect of this gene and is associated with several inflammatory diseases including periodontitis. Aim: To detect Endothelial Nitric Oxide Synthase intron 4 gene polymorphism in Indonesian population with periodontitis. Analysis of the Endothelial Nitric Oxide Synthase (eNOS) intron 4 gene polymorphism was observed by carrying out PCR method followed by electrophoresis for the analysis, without the usage of restriction enzyme. The chi-square test and odds ratio were performed for statistical analysis. In this study, there were 34 samples with AA genotype, 3 samples with AB genotype, and 13 samples with BB genotype in periodontitis group. Whereas in the control group, there were 41 samples with AA genotype and 9 samples with BB genotype. AB genotype was absent in the control group. In periodontitis group, there were 71 A alleles and 29 B alleles, and in the control group, 82 A alleles and 18 B alleles were found. Polymorphic genotypes and alleles were found higher in periodontitis sample (32% and 29%) than healthy controls (18%). The polymorphism of eNOS intron 4 was found in periodontitis patients. There is no significant distribution difference was found between the periodontitis patients and the control group. ENOS intron 4 gene polymorphism does not affect the risk of periodontitis. © Published under licence by IOP Publishing Ltd. |
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Electrophoresis; Genes; Nitric oxide; Polymerase chain reaction; Polymorphism; Statistical tests; Endothelial nitric oxide synthase; Endothelial nitric-oxide synthase (eNOS); Functional aspects; Gene polymorphism; Inflammatory disease; Nitric-oxide synthase; Periodontal tissue; Restriction enzymes; Diseases |
IOP Publishing Ltd |
17426588 |
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Conference Paper |
Q4 |
210 |
18731 |
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281 |
Gani A.Z., Zahra P.K., Soedarsono N., Yunaini L., Auerkari E.I. |
57222626782;57226565453;14049161500;57192911515;10139113000; |
Vitamin D receptor TaqI (rs731236) gene polymorphism in caries patients |
2021 |
Journal of Physics: Conference Series |
1943 |
1 |
012093 |
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https://www.scopus.com/inward/record.uri?eid=2-s2.0-85112014710&doi=10.1088%2f1742-6596%2f1943%2f1%2f012093&partnerID=40&md5=5891ab3c26dbd9bd14c0be24643600b3 |
Department of Oral Biology, Faculty of Dentistry, University of Indonesia, Jakarta, Indonesia; Department of Medical Biology, Faculty of Medicine, University of Indonesia, Jakarta, Indonesia |
Gani, A.Z., Department of Oral Biology, Faculty of Dentistry, University of Indonesia, Jakarta, Indonesia; Zahra, P.K., Department of Oral Biology, Faculty of Dentistry, University of Indonesia, Jakarta, Indonesia; Soedarsono, N., Department of Oral Biology, Faculty of Dentistry, University of Indonesia, Jakarta, Indonesia; Yunaini, L., Department of Medical Biology, Faculty of Medicine, University of Indonesia, Jakarta, Indonesia; Auerkari, E.I., Department of Oral Biology, Faculty of Dentistry, University of Indonesia, Jakarta, Indonesia |
Vitamin D receptor (VDR) is included in the type of protein that serves as the biological function regulator of vitamin D. Tooth formation, especially in enamel and dentin calcification, as well as maintaining the balance of phosphate and calcium ions which is an important factor in protecting teeth requires support from vitamin D. The VDR gene will regulate the activity of VDR proteins. Caries is a multifactorial disease in which genetic factors can affect the host susceptibility to caries. Polymorphism in the VDR gene is suspected to affect the host susceptibility to caries through changes in calcium metabolism. This study aims to discover the VDR gene polymorphism and its association with caries patients in Indonesia. 100 DNA samples from 100 blood samples, including 50 dental caries patients and 50 healthy controls, were analyzed using PCR-RFLP technique. PCR products were digested with the TaqI restrictive enzyme, then assessed with statistical analysis using Fisher's exact test and Continuity correction test. In the caries group, there were no samples with CC genotype, 4 samples with CT genotype, and 46 samples with TT genotype. There were also 4 C alleles and 96 T alleles. Polymorphic genotypes and alleles were found higher in the caries group (100% and 96%) than healthy controls (88% and 84%). These results conclude that the polymorphism of VDR TaqI (rs731236) gene was found in patients with dental caries. The distribution of genotypes and allele distributions of VDR TaqI (rs731236) gene between caries and healthy controls significantly differs noticeable (p <0.05). © Published under licence by IOP Publishing Ltd. |
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Biomineralization; Calcium; Polymerase chain reaction; Polymorphism; Proteins; Vitamins; Biological functions; Calcium metabolism; Continuity corrections; Gene polymorphism; Healthy controls; Host susceptibility; Multifactorial disease; Vitamin D receptor; Genes |
IOP Publishing Ltd |
17426588 |
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Conference Paper |
Q4 |
210 |
18731 |
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302 |
Menaldi S.L., Dinakrisma A.A., Thio H.B., Rengganis I., Oktaria S. |
57192918198;57208817505;6603706049;8449988000;57189897691; |
Unusual presentations of a severe type 2 leprosy reaction mimicking sepsis induced by helminth infection |
2021 |
PLoS Neglected Tropical Diseases |
15 |
7 |
e0009453 |
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https://www.scopus.com/inward/record.uri?eid=2-s2.0-85112233539&doi=10.1371%2fjournal.pntd.0009453&partnerID=40&md5=ca1861c9fbca4ae66dbabcdc89952023 |
Department of Dermatology and Venereology, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Department of Internal Medicine, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Department of Dermatology, Erasmus University Medical Center, Rotterdam, Netherlands |
Menaldi, S.L., Department of Dermatology and Venereology, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Dinakrisma, A.A., Department of Internal Medicine, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Thio, H.B., Department of Dermatology, Erasmus University Medical Center, Rotterdam, Netherlands; Rengganis, I., Department of Internal Medicine, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Oktaria, S., Department of Dermatology and Venereology, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia, Department of Dermatology, Erasmus University Medical Center, Rotterdam, Netherlands |
AU: Pleaseconfirmthatallheadinglevelsarerepresentedcorrectly: We describe an unusual case of type 2 leprosy reaction (T2R) with septic shock–like features induced by helminth infection in a 31-year-old Moluccan male patient with a history of completed treatment of WHO multidrug therapy (MAU: PleasenotethatMDThasbeendefinedasmultidrugt DT)–multibacillary (MB) regimen 2 years before admission. During the course of illness, the patient had numerous complications, including septic shock, anemia, and disseminated intravascular coagulation (DIC). Nevertheless, antibiotic therapies failed to give significant results, and the source of infection could not be identified. Helminth infection was subsequently revealed by endoscopic examination followed by parasitological culture. Resolution of symptoms and normal level of organ function–specific markers were resolved within 3 days following anthelmintic treatment. This report demonstrated the challenge in the diagnosis and treatment of severe T2R. Given that helminth infections may trigger severe T2R that mimics septic shock, health professionals need to be aware of this clinical presentation, especially in endemic regions of both diseases. © 2021 Fongwen et al. |
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leprostatic agent; adult; animal; case report; classification; complication; genetics; helminth; helminthiasis; human; isolation and purification; leprosy; male; opportunistic infection; parasitology; sepsis; Adult; Animals; Helminthiasis; Helminths; Humans; Leprostatic Agents; Leprosy; Male; Opportunistic Infections; Sepsis |
Public Library of Science |
19352727 |
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34314436 |
Article |
Q1 |
1990 |
1322 |
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308 |
Sartika A.N., Khoirunnisa M., Meiyetriani E., Ermayani E., Pramesthi I.L., Nur Ananda A.J. |
57221416383;57226010121;57209855172;57207767542;57225987145;57225998001; |
Prenatal and postnatal determinants of stunting at age 0–11 months: A cross-sectional study in Indonesia |
2021 |
PLoS ONE |
16 |
7 July |
e0254662 |
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https://www.scopus.com/inward/record.uri?eid=2-s2.0-85110244631&doi=10.1371%2fjournal.pone.0254662&partnerID=40&md5=49e2d8b93ae14f38dd5a7a1c9f3b9765 |
Department of Nutrition, Faculty of Medicine Universitas Indonesia, Jakarta, Indonesia; SEAMEO Regional Center for Food and Nutrition, Pusat Kajian Gizi Regional Universitas Indonesia, Jakarta, Indonesia |
Sartika, A.N., Department of Nutrition, Faculty of Medicine Universitas Indonesia, Jakarta, Indonesia; Khoirunnisa, M., Department of Nutrition, Faculty of Medicine Universitas Indonesia, Jakarta, Indonesia; Meiyetriani, E., SEAMEO Regional Center for Food and Nutrition, Pusat Kajian Gizi Regional Universitas Indonesia, Jakarta, Indonesia; Ermayani, E., SEAMEO Regional Center for Food and Nutrition, Pusat Kajian Gizi Regional Universitas Indonesia, Jakarta, Indonesia; Pramesthi, I.L., SEAMEO Regional Center for Food and Nutrition, Pusat Kajian Gizi Regional Universitas Indonesia, Jakarta, Indonesia; Nur Ananda, A.J., SEAMEO Regional Center for Food and Nutrition, Pusat Kajian Gizi Regional Universitas Indonesia, Jakarta, Indonesia |
Background Childhood stunting remains the most challenging consequence of undernutrition because it is associated with suboptimal brain development and the subsequent increased risk of metabolic diseases and decreased earnings in adult life. The Sambas District in Indonesia has a high prevalence of stunting (28.4%), followed by underweight (25.5.%) and wasting (14.4%) among children, as well chronic energy deficiency (27%) and anemia (62%) among pregnant women. The present study sought to determine significant factors in childhood stunting with a focus on maternal and child nutrition and prenatal and postnatal determinants. Methods This prospective, repeat, cross-sectional study investigated factors associated with stunting among 559 infants age 0–11 months in Sambas District, Indonesia. Anthropometric measurements were performed by trained enumerators. Data from a 2016 survey of pregnant women and a 2017 survey on mothers and their children were used for postnatal data collection to quantify the prevalence of stunting at age 0–11 months. Using 20 potential predictors of stunting categorized by household characteristics, maternal characteristics, antenatal care services, and child characteristics, logistic regression analysis was conducted to assess the adjusted association between stunting and these factors. Results Of 559 children analyzed, 20.8% were stunted. In the model with low birth weight (LBW) as predictor for stunting, the odds of stunting increased significantly among children who weighed <2.500 g at birth; children who had diarrhea in the past 2 weeks and children who had incomplete basic immunization coverage as infants age 9–11 months. In model without LBW, the odds of stunting increased significantly among children who had preterm at birth, short maternal stature and children who had incomplete basic immunization coverage for 9–11 months infants. Conclusions Postnatal factors—preterm birth, low birth weight, diarrhea and complete basic immunization coverage—were associated with infant stunting in Sambas District, Indonesia. The prenatal factors such as short maternal stature were significant in the multivariate model. Policy makers, especially in the government, should recommend measures focused on those prenatal and postnatal factors to prevent stunting in children and to avoid the sequelae of childhood stunting in adult life. Copyright: © 2021 Sartika et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. |
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anthropometry; Article; child nutrition; cross-sectional study; data collection method; diarrhea; female; government; health care policy; household; human; Indonesia; infant; low birth weight; major clinical study; male; maternal nutrition; newborn; perinatal period; predictor variable; premature labor; prenatal care; prenatal period; prevalence; prospective study; stunting; vaccination coverage; growth disorder; multivariate analysis; Anthropometry; Cross-Sectional Studies; Female; Growth Disorders; Humans; Indonesia; Infant; Infant, Newborn; Male; Multivariate Analysis; Prospective Studies |
Public Library of Science |
19326203 |
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34260622 |
Article |
Q1 |
990 |
4434 |
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322 |
Fuady A., Khoe L.C., Azzahra T.B., Lestari H.M., Sutanto R.L., Yo E.C., Suryoadji K.A., Sudarsono N.C., Findyartini A. |
37085331400;56586245200;57223601523;57223631169;57222060277;57213188908;57223633894;57201862518;56543777300; |
Good Knowledge but Poor Practice Toward COVID-19 Among Indonesian Youth |
2021 |
Asia-Pacific Journal of Public Health |
33 |
5 |
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605 |
607 |
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1 |
https://www.scopus.com/inward/record.uri?eid=2-s2.0-85105912511&doi=10.1177%2f10105395211015048&partnerID=40&md5=eeb26dde9d980d4470234af3a533b0c1 |
Department of Community Medicine, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Undergraduate Medical Program, Faculty of Medicine, Indonesia; Medical Education Center, Indonesia Medical Education Research Institute (IMERI), Faculty of Medicine, Universitas Indonesia, Indonesia; Center for Sports and Exercise Studies, Indonesia Medical Education and Research Institute (IMERI), Faculty of Medicine Universitas Indonesia, Indonesia; Department of Medical Education, Faculty of Medicine, Indonesia |
Fuady, A., Department of Community Medicine, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Khoe, L.C., Department of Community Medicine, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Azzahra, T.B., Undergraduate Medical Program, Faculty of Medicine, Indonesia, Medical Education Center, Indonesia Medical Education Research Institute (IMERI), Faculty of Medicine, Universitas Indonesia, Indonesia; Lestari, H.M., Undergraduate Medical Program, Faculty of Medicine, Indonesia, Medical Education Center, Indonesia Medical Education Research Institute (IMERI), Faculty of Medicine, Universitas Indonesia, Indonesia; Sutanto, R.L., Undergraduate Medical Program, Faculty of Medicine, Indonesia, Medical Education Center, Indonesia Medical Education Research Institute (IMERI), Faculty of Medicine, Universitas Indonesia, Indonesia; Yo, E.C., Undergraduate Medical Program, Faculty of Medicine, Indonesia, Medical Education Center, Indonesia Medical Education Research Institute (IMERI), Faculty of Medicine, Universitas Indonesia, Indonesia; Suryoadji, K.A., Undergraduate Medical Program, Faculty of Medicine, Indonesia, Medical Education Center, Indonesia Medical Education Research Institute (IMERI), Faculty of Medicine, Universitas Indonesia, Indonesia; Sudarsono, N.C., Department of Community Medicine, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia, Center for Sports and Exercise Studies, Indonesia Medical Education and Research Institute (IMERI), Faculty of Medicine Universitas Indonesia, Indonesia; Findyartini, A., Medical Education Center, Indonesia Medical Education Research Institute (IMERI), Faculty of Medicine, Universitas Indonesia, Indonesia, Department of Medical Education, Faculty of Medicine, Indonesia |
[No abstract available] |
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SAGE Publications Inc. |
10105395 |
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33998316 |
Article |
Q2 |
572 |
8837 |
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328 |
Sihotang R.C., Alvonico T., Taher A., Birowo P., Rasyid N., Atmoko W. |
57216755881;57216743520;7005269743;6504153311;56245069300;57193125664; |
Premature ejaculation in patients with lower urinary tract symptoms: a systematic review |
2021 |
International Journal of Impotence Research |
33 |
5 |
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516 |
524 |
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2 |
https://www.scopus.com/inward/record.uri?eid=2-s2.0-85084492871&doi=10.1038%2fs41443-020-0298-5&partnerID=40&md5=243ef2c5fa8e96c70ec2e3eb9ca5b534 |
Faculty of Medicine, Universitas Indonesia, No. 6, Salemba Raya Road, DKI Jakarta, 10430, Indonesia; Department of Urology, Cipto Mangunkusumo National Hospital, Diponegoro Road, DKI Jakarta, 10430, Indonesia |
Sihotang, R.C., Faculty of Medicine, Universitas Indonesia, No. 6, Salemba Raya Road, DKI Jakarta, 10430, Indonesia; Alvonico, T., Faculty of Medicine, Universitas Indonesia, No. 6, Salemba Raya Road, DKI Jakarta, 10430, Indonesia; Taher, A., Department of Urology, Cipto Mangunkusumo National Hospital, Diponegoro Road, DKI Jakarta, 10430, Indonesia; Birowo, P., Department of Urology, Cipto Mangunkusumo National Hospital, Diponegoro Road, DKI Jakarta, 10430, Indonesia; Rasyid, N., Department of Urology, Cipto Mangunkusumo National Hospital, Diponegoro Road, DKI Jakarta, 10430, Indonesia; Atmoko, W., Department of Urology, Cipto Mangunkusumo National Hospital, Diponegoro Road, DKI Jakarta, 10430, Indonesia |
Lower urinary tract symptoms (LUTS) refer to a group of symptoms related to bladder, prostate, and urethra. LUTS are common in men and the severity increases with age. LUTS are frequently associated with sexual dysfunction, such as premature ejaculation (PE), standing as the most common sexual dysfunction in men. Both LUTS and PE cause distress and dissatisfaction for the patient and his partner. This systematic review aims to determine the relationship between LUTS and PE in men. Two reviewers independently conduct a literature search in five online databases (PubMed, Scopus, Proquest, ClinicalKey, and ScienceDirect). In addition, reviewers also reviewed the reference list of chosen articles to identify additional relevant studies. Twelve articles were included in this systematic review that consists of one cohort study and 11 cross-sectional studies. The total scores of each identified study ranged from “poor” to “good.” The prevalence of PE in LUTS ranged from 12 to 77%. Most of the studies showed a significant relationship between LUTS and PE. PE is more common in older age with the peak prevalence in age of 60–69 years old. There is a possible association between PE and LUTS. Further research using cohort or case-control study design on this topic is needed. © 2020, The Author(s), under exclusive licence to Springer Nature Limited. |
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age; human; International Prostate Symptom Score; male; outcome assessment; premature ejaculation; prevalence; prostatectomy; Review; systematic review; urinary tract infection; aged; case control study; cohort analysis; complication; cross-sectional study; ejaculation; lower urinary tract symptom; middle aged; premature ejaculation; Aged; Case-Control Studies; Cohort Studies; Cross-Sectional Studies; Ejaculation; Humans; Lower Urinary Tract Symptoms; Male; Middle Aged; Premature Ejaculation |
Springer Nature |
09559930 |
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32393845 |
Review |
Q2 |
508 |
9947 |
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333 |
Ngadimin K.D., Stokes A., Gentile P., Ferreira A.M. |
57224568038;57224586577;24478479500;16068361700; |
Biomimetic hydrogels designed for cartilage tissue engineering |
2021 |
Biomaterials Science |
9 |
12 |
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4246 |
4259 |
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15 |
https://www.scopus.com/inward/record.uri?eid=2-s2.0-85107619348&doi=10.1039%2fd0bm01852j&partnerID=40&md5=634f8d458d06a53948b28ba7237188d1 |
Faculty of Medical Sciences, Newcastle University, Newcastle upon Tyne, United Kingdom; Faculty of Medicine, Universitas Indonesia, Indonesia; Faculty of Science, Agriculture and Engineering, Newcastle University, Newcastle upon Tyne, United Kingdom |
Ngadimin, K.D., Faculty of Medical Sciences, Newcastle University, Newcastle upon Tyne, United Kingdom, Faculty of Medicine, Universitas Indonesia, Indonesia; Stokes, A., Faculty of Science, Agriculture and Engineering, Newcastle University, Newcastle upon Tyne, United Kingdom; Gentile, P., Faculty of Science, Agriculture and Engineering, Newcastle University, Newcastle upon Tyne, United Kingdom; Ferreira, A.M., Faculty of Science, Agriculture and Engineering, Newcastle University, Newcastle upon Tyne, United Kingdom |
Cartilage regeneration and repair remain a clinical challenge due to the limited capability of cartilage to self-regenerate. Worldwide, the costs associated with cartilage regeneration per patient are estimated on average £30 000 for producing and supplying cells. Regenerative approaches may include the use of cell therapies and tissue engineering by combining relevant cells, scaffolds and instructive biomolecules to stimulate or modulate cartilage repair. Hydrogels have been of great interest within these fields to be used as 3D substrates to cultivate and grow cartilage cells. Currently, biomimetic hydrogels with adequate biological and physicochemical properties, such as mechanical properties, capable of supporting load-bearing capability, are yet to succeed. In this review, biomaterials' advantages and disadvantages for the manufacturing of biomimetic hydrogels for cartilage regeneration are presented. Different studies on the formulation of cartilage-like hydrogels based on materials such as gelatin, chondroitin sulfate, hyaluronic acid and polyethylene glycol are summarised and contrasted in terms of their mechanical properties (e.g. elastic modulus) and ability to enhance cell function such as cell viability and GAG content. Current limitations and challenges of biomimetic hydrogels for cartilage regeneration are also presented. © 2021 The Royal Society of Chemistry. |
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Biomechanics; Biomimetics; Cartilage; Cells; Cytology; Hyaluronic acid; Hydrogels; Mechanical properties; Molecular biology; Physicochemical properties; Scaffolds (biology); Sulfur compounds; Tissue; Biomimetic hydrogels; Cartilage cells; Cartilage regeneration; Cartilage repair; Cartilage tissue engineering; Chondroitin sulfates; Current limitation; Load bearing capabilities; Cell engineering; biomaterial; biomimetic material; chondroitin sulfate; gelatin; hyaluronic acid; hydrogel; macrogol; biological activity; biomimetics; cartilage; cell therapy; cell viability; chemical composition; computer model; cross linking; human; in vitro study; nonhuman; Review; tissue engineering; tissue regeneration; Young modulus; articular cartilage; biomimetics; cartilage; hydrogel; regeneration; tissue |
Royal Society of Chemistry |
20474830 |
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33710205 |
Review |
Q1 |
1422 |
2479 |
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337 |
Pontoh L.A.P., Rahyussalim A.J., Fiolin J. |
57192907426;55212166100;57194498274; |
Patient Height may Predict the Length of the Anterior Cruciate Ligament: A Magnetic Resonance Imaging Study |
2021 |
Arthroscopy, Sports Medicine, and Rehabilitation |
3 |
3 |
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e733 |
e739 |
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https://www.scopus.com/inward/record.uri?eid=2-s2.0-85113913987&doi=10.1016%2fj.asmr.2021.01.012&partnerID=40&md5=f360a46041bd0cd832150f6f545b6417 |
Knee Division of Department of Orthopaedic and Traumatology, Fatmawati General Hospital–Faculty of Medicine Universitas Indonesia, Jakarta, Selatan, Indonesia; Spine Division of Department of Orthopaedic and Traumatology, Dr. Cipto Mangunkusumo General Hospital–Faculty of Medicine Universitas Indonesia, Jakarta, Pusat, Indonesia; Jakarta Knee, Shoulder and Orthopaedic Sport Clinic, Pondok Indah Hospital, Jakarta, Indonesia |
Pontoh, L.A.P., Knee Division of Department of Orthopaedic and Traumatology, Fatmawati General Hospital–Faculty of Medicine Universitas Indonesia, Jakarta, Selatan, Indonesia; Rahyussalim, A.J., Spine Division of Department of Orthopaedic and Traumatology, Dr. Cipto Mangunkusumo General Hospital–Faculty of Medicine Universitas Indonesia, Jakarta, Pusat, Indonesia; Fiolin, J., Jakarta Knee, Shoulder and Orthopaedic Sport Clinic, Pondok Indah Hospital, Jakarta, Indonesia |
Purpose: The purpose of this study was to measure the length and width of anterior cruciate ligament (ACL) tibial footprint using magnetic resonance imaging (MRI) and to evaluate correlation between patients’ weight and height with the tibial footprint size. Methods: In total, 207 eligible patients underwent MRI scanning from June 2018 to June 2020. One hundred seventeen knees from patients aged 18 to 40 years old with intact ACL were included in this study. Data of weight, height, body mass index (BMI) from physical examination and tibial footprint length and width from MRI were obtained. Relationship of ACL tibial footprint length <14 mm and association between ACL tibial footprint sizes of MRI with height, weight, and BMI were analyzed. Results: The ACL tibial footprint length and width were, respectively, 11.9 ± 1.8 mm and 10 ± 1.5 mm. Proportion of ACL footprint <14 mm in length was 89.7%. Patient height ≥170 cm was the best predictor of ACL tibial footprint length <14 mm (P =.025). There was a statistically significant relationship between the height of the patients and the length of the ACL tibial footprint. The length of the ACL tibial footprint could be predicted by the formula: length = −7.362 + 11.48 × (height in meters). Conclusion: The height of the patients may predict the length of the ACL tibial footprint. Although patient's age, sex, and BMI correlate poorly with ACL tibial footprint width, there was no correlation between patient's weight and ACL tibial footprint size. Clinical Relevance: Before ACL reconstruction surgery, an estimation of ACL tibial footprint size might aid in the graft harvesting preparation. © 2021 Arthroscopy Association of North America |
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adult; anterior cruciate ligament; anterior cruciate ligament reconstruction; article; body mass; body weight; clinical evaluation; controlled study; female; graft harvesting; human; major clinical study; male; nuclear magnetic resonance imaging; physical examination |
Elsevier Inc. |
2666061X |
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