No records
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106 |
Tobing S.D.A.L., Hendriarto A., Wikanjaya R. |
57192893142;57216821517;57211909508; |
Conservative approach for treatment of Grisel's syndrome after resection of lympahadenitis tuberculosis of the neck: A rare case report |
2021 |
International Journal of Surgery Case Reports |
88 |
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106452 |
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https://www.scopus.com/inward/record.uri?eid=2-s2.0-85116936259&doi=10.1016%2fj.ijscr.2021.106452&partnerID=40&md5=a61504c984a695791169d7a4a2464b5f |
Orthopaedic and Traumatology Department, Dr. Cipto Mangunkusumo Hospital, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia |
Tobing, S.D.A.L., Orthopaedic and Traumatology Department, Dr. Cipto Mangunkusumo Hospital, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Hendriarto, A., Orthopaedic and Traumatology Department, Dr. Cipto Mangunkusumo Hospital, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Wikanjaya, R., Orthopaedic and Traumatology Department, Dr. Cipto Mangunkusumo Hospital, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia |
Introduction: Grisel's syndrome is a rare condition characterized by nontraumatic rotatory subluxation of the atlantoaxial joint, which was caused by previous inflammation around the head and neck. It is usually seen in children and signed as torticollis. There was no consensus for management, yet early diagnosis and treatment is paramount. Presentation of case: A 5-year-old girl came to outpatient clinic complaining of wry neck 1 day after surgical excision of her TB lymphadenitis and got worsen by time. There was no history of trauma around the neck. Examination under general anesthesia and CT scan revealed acquired severe torticollis consistent with Grisel's Syndrome Fielding type 3 accompanied by TB lymphadenitis, and TB myositis of the neck. Manipulation under general anesthesia and immobilization using Minerva cast followed by Lerman Cervicothoracal Osthosis was conducted. Discussion: This patient was diagnosed with Grisel's syndrome and underwent conservative treatment consisting of reduction under general anesthesia and immobilization using Minerva cast for 6 weeks. The patient was then applied Lherman Cervical Thoracic Orthosis (CTO) halo brace for another 3 months. Anti-tuberculous drug was given to control tuberculous infection. Eight months follow-up showed neither residual deformity, neck pain, nor movement limitation of the neck. Conclusion: Grisel's syndrome has excellent result that is treated with conservative treatment using reduction under general anesthesia and Minerva cast. © 2021 The Authors |
Acquired torticollis; Conservative; Grisel's syndrome; Minerva cast |
cobamamide; cyproheptadine; tuberculostatic agent; Article; atlantoaxial subluxation; body weight gain; case report; cervical lymph node; child; clinical article; computer assisted tomography; conservative treatment; disease exacerbation; excision; excisional biopsy; female; fever; follow up; general anesthesia; Grisel syndrome; headache; histopathology; hoarseness; human; human tissue; immobilization; infection control; interferon gamma release assay; Langhans giant cell; loss of appetite; lymphadenitis; myositis; nausea; neck malformation; neuroimaging; night sweat; nuclear magnetic resonance imaging; outpatient department; physical examination; preschool child; puncture; range of motion; sternocleidomastoid muscle; torticollis; tuberculin test; tuberculous lymphadenitis |
Elsevier Ltd |
22102612 |
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Article |
Q3 |
232 |
17549 |
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107 |
Poerbonegoro N.L., Reksodiputro M.H., Sari D.P., Mufida T., Rahman M.A., Reksodiputro L.A., Audindra S., Yosia M. |
57222574894;35090488800;57292553600;57291865900;57291413400;57292781100;57222006228;57204933098; |
Cross-sectional study on the proportion of smell and taste disturbances in hospitalized COVID-19 patients |
2021 |
Annals of Medicine and Surgery |
71 |
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102909 |
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https://www.scopus.com/inward/record.uri?eid=2-s2.0-85116899241&doi=10.1016%2fj.amsu.2021.102909&partnerID=40&md5=96e678393268c92055e16d284f8c40f7 |
Otorhinolaryngology-Head Neck Surgery Medical Staff Group, Universitas Indonesia Hospital, Depok, West Java, Indonesia; Faculty of Medicine Universitas Indonesia, Jakarta, Indonesia |
Poerbonegoro, N.L., Otorhinolaryngology-Head Neck Surgery Medical Staff Group, Universitas Indonesia Hospital, Depok, West Java, Indonesia; Reksodiputro, M.H., Otorhinolaryngology-Head Neck Surgery Medical Staff Group, Universitas Indonesia Hospital, Depok, West Java, Indonesia; Sari, D.P., Otorhinolaryngology-Head Neck Surgery Medical Staff Group, Universitas Indonesia Hospital, Depok, West Java, Indonesia; Mufida, T., Faculty of Medicine Universitas Indonesia, Jakarta, Indonesia; Rahman, M.A., Faculty of Medicine Universitas Indonesia, Jakarta, Indonesia; Reksodiputro, L.A., Faculty of Medicine Universitas Indonesia, Jakarta, Indonesia; Audindra, S., Faculty of Medicine Universitas Indonesia, Jakarta, Indonesia; Yosia, M., Faculty of Medicine Universitas Indonesia, Jakarta, Indonesia |
Background: The number of confirmed Coronavirus Disease-2019 (COVID-19) cases in Indonesia had reached 1.4 million cases from a total population of 270 million. Smell and/or taste disturbances are frequently found as early symptoms of COVID-19 patients. Our study aimed to investigate the proportion and characteristics of anosmia and/or ageusia in COVID-19. Materials and methods: This cross-sectional study identifies the proportion and severity of smell and taste disturbances in COVID-19 patients. Subjects were recruited by consecutive sampling. All subjects were required to fill in the questionnaire modified from the American Academy of Otolaryngology-Head and Neck Surgery Anosmia Reporting Tool (AAO-HNS ART). Symptoms severity was measured with a numerical rating scale of 0–10; 0–3 is defined as mild, 4–6 as moderate, and 7–10 as severe. Results: Out of 51 subjects, 34 (66.7%) suffered from smell and/or taste disturbances. Twenty-nine of 34 subjects (85.3%) suffered from smell disturbance, and 24 of 34 subjects (70.5%) suffered from taste disturbance. Severe smell disturbance occurred in 68.9% of subjects, while severe taste disturbance occurred in 50%. The median onset was three days for smell disturbance and four days for taste disturbance after any symptoms of COVID-19. Conclusion: Smell and/or taste disturbances were early symptoms of COVID-19. These symptoms commonly occurred within the first four days of clinical onset and frequently manifested in severe conditions. © 2021 |
Ageusia; Anosmia; COVID-19; Indonesia |
adult; American Academy of Otolaryngology Head and Neck Surgery Anosmia Reporting Tool; Article; coronavirus disease 2019; cross-sectional study; disease assessment; disease severity; female; human; major clinical study; male; numeric rating scale; questionnaire; real time polymerase chain reaction; retrospective study; risk factor; smelling disorder; taste disorder; visual analog scale |
Elsevier Ltd |
20490801 |
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Article |
Q3 |
391 |
12334 |
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108 |
Liberty I.A., Kodim N., Sartika R.A.D., Trihandini I., Tjekyan R.M.S., Zulkarnain, Pane M., Pratisthita L.B., Tahapary D.L., Soewondo P. |
57211435130;57210444174;41862490800;8449988100;57267287700;57267073300;55831164800;57221504201;55944492500;23475336100; |
Triglyceride/Glucose Index (TyG Index) as a marker of glucose status conversion among reproductive-aged women in Jakarta, Indonesia: The Bogor cohort study (2011–2016) |
2021 |
Diabetes and Metabolic Syndrome: Clinical Research and Reviews |
15 |
6 |
102280 |
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https://www.scopus.com/inward/record.uri?eid=2-s2.0-85115349587&doi=10.1016%2fj.dsx.2021.102280&partnerID=40&md5=db55d7f5dcad157ad5a355acd19a0c89 |
Department of Public Health and Community Medicine, University of Sriwijaya, Indonesia; Department of Epidemiology, Public Health Faculty, Universitas Indonesia, Depok, Indonesia; Department of Public Nutrition, Public Health Faculty Universitas Indonesia, Depok, Indonesia; Department of Biostatistics, Public Health Faculty Universitas Indonesia, Depok, Indonesia; National Institute Health Research and Development, Ministry of Health of the Republic of Indonesia, Indonesia; Metabolic, Cardiovascular, and Aging Cluster, The Indonesian Medical Education and Research Institute, Faculty of Medicine Universitas Indonesia, Jakarta, Indonesia; Department of Internal Medicine, Universitas Indonesia Hospital, Depok, Indonesia; Division of Endocrinology, Metabolism and Diabetes, Department of Internal Medicine, Dr. Cipto Mangunkusumo National Referral Hospital, Faculty of Medicine Universitas Indonesia, Jakarta, Indonesia |
Liberty, I.A., Department of Public Health and Community Medicine, University of Sriwijaya, Indonesia, Department of Epidemiology, Public Health Faculty, Universitas Indonesia, Depok, Indonesia; Kodim, N., Department of Epidemiology, Public Health Faculty, Universitas Indonesia, Depok, Indonesia; Sartika, R.A.D., Department of Public Nutrition, Public Health Faculty Universitas Indonesia, Depok, Indonesia; Trihandini, I., Department of Biostatistics, Public Health Faculty Universitas Indonesia, Depok, Indonesia; Tjekyan, R.M.S., Department of Public Health and Community Medicine, University of Sriwijaya, Indonesia; Zulkarnain, Department of Public Health and Community Medicine, University of Sriwijaya, Indonesia; Pane, M., National Institute Health Research and Development, Ministry of Health of the Republic of Indonesia, Indonesia; Pratisthita, L.B., Metabolic, Cardiovascular, and Aging Cluster, The Indonesian Medical Education and Research Institute, Faculty of Medicine Universitas Indonesia, Jakarta, Indonesia, Department of Internal Medicine, Universitas Indonesia Hospital, Depok, Indonesia; Tahapary, D.L., Metabolic, Cardiovascular, and Aging Cluster, The Indonesian Medical Education and Research Institute, Faculty of Medicine Universitas Indonesia, Jakarta, Indonesia, Division of Endocrinology, Metabolism and Diabetes, Department of Internal Medicine, Dr. Cipto Mangunkusumo National Referral Hospital, Faculty of Medicine Universitas Indonesia, Jakarta, Indonesia; Soewondo, P., Metabolic, Cardiovascular, and Aging Cluster, The Indonesian Medical Education and Research Institute, Faculty of Medicine Universitas Indonesia, Jakarta, Indonesia, Division of Endocrinology, Metabolism and Diabetes, Department of Internal Medicine, Dr. Cipto Mangunkusumo National Referral Hospital, Faculty of Medicine Universitas Indonesia, Jakarta, Indonesia |
Background and aims: Reproductive-aged women are prone to type 2 diabetes mellitus. This study aims to evaluate the optimal cut off point of Triglyceride/Glucose Index for predicting glucose status conversion among women of reproductive age. Methods: This study involved normoglycemic and prediabetes women aged 20–49 years from the Bogor Non-Communicable Diseases Cohort Study (West Java, Indonesia) conducted from 2011 to 2016. Statistical analysis was performed using Receiver Operating Characteristics curve analysis with STATA version 15. Results: Among prediabetes subjects (n = 371), the cut-off point of TyG index for regression from prediabetes to normoglycemic subjects was <4.51 [sensitivity, specificity, AUC (95%CI) 83.9%, 80.1%, 0.913 (0.875–0.943), respectively] and the cut-off point for progression from prediabetes to diabetes was >4.54 [80.0%, 73.1%, 0.858 (0.807–0.900)]. Among normoglycemic subjects (n = 1300), the cut-off point of TyG index for progression to prediabetes and diabetes were >4.44 [80.1%, 71.1%, 0.834 (0.812–0.854)] and >4.47 [80.6%, 80.8%, 0.909 (0.890–0.926)] respectively. Conclusion: Based on sample of subjects evaluated between 2011 and 2016, TyG index appears to be a promising marker for glucose status conversion among reproductive-aged women in Jakarta, Indonesia. © 2021 |
Conversion; Glucose; Reproductive; TyG index; Women |
biological marker; cholesterol; glucose; hemoglobin A1c; high density lipoprotein cholesterol; low density lipoprotein cholesterol; triacylglycerol; adult; Article; cholesterol blood level; cohort analysis; controlled study; data analysis software; diabetes mellitus; evaluation study; female; follow up; glucose blood level; groups by age; human; impaired glucose tolerance; Indonesia; major clinical study; middle aged; oral glucose tolerance test; outcome assessment; predictive value; receiver operating characteristic; reference value; remission; reproduction; retrospective study; sensitivity and specificity; statistical analysis; triacylglycerol blood level; triglyceride glucose index; young adult |
Elsevier Ltd |
18714021 |
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34562866 |
Article |
Q2 |
684 |
7304 |
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111 |
Baskoro J.C., Hadi I.A.N., Ekaputri M., Winarsih N.S. |
57242005500;57242308100;57242005600;57211183552; |
Correlation between duration of untreated psychosis and working memory in early-onset psychotic disorders |
2021 |
Personalized Medicine in Psychiatry |
29-30 |
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100084 |
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https://www.scopus.com/inward/record.uri?eid=2-s2.0-85114078676&doi=10.1016%2fj.pmip.2021.100084&partnerID=40&md5=56d11228ab6c85aba3075e3f4f99e800 |
Department of Psychiatry, Faculty of Medicine, Universitas Indonesia, Jl. Salemba Raya 6, Jakarta Pusat, DKI, Jakarta, 10430, Indonesia |
Baskoro, J.C., Department of Psychiatry, Faculty of Medicine, Universitas Indonesia, Jl. Salemba Raya 6, Jakarta Pusat, DKI, Jakarta, 10430, Indonesia; Hadi, I.A.N., Department of Psychiatry, Faculty of Medicine, Universitas Indonesia, Jl. Salemba Raya 6, Jakarta Pusat, DKI, Jakarta, 10430, Indonesia; Ekaputri, M., Department of Psychiatry, Faculty of Medicine, Universitas Indonesia, Jl. Salemba Raya 6, Jakarta Pusat, DKI, Jakarta, 10430, Indonesia; Winarsih, N.S., Department of Psychiatry, Faculty of Medicine, Universitas Indonesia, Jl. Salemba Raya 6, Jakarta Pusat, DKI, Jakarta, 10430, Indonesia |
Psychotic disorders are morbid mental disorders that impair working memory. Theory suggests that longer duration of untreated psychosis (DUP) results in worse working memory. However, results from previous studies are contradictory, with no study having been conducted in children. This study aims at finding out the association between duration of untreated psychosis and working memory in children. This is a cross-sectional study with 45 subjects. DUP was collected from medical records whereas working memory was measured using digit span backward raw score. Average digit span backward scores of subjects was 3.7 ± 1.18. Analysis using Spearman test showed no significant association (p = 0.128) between DUP and working memory. In conclusion, there is no association between DUP and working memory in children, therefore we recommend that psychiatrists pay attention to working memory impairment in all pediatric patients with psychotic disorders, regardless of their DUP. © 2021 Elsevier Inc. |
Children; Duration of untreated psychosis; Psychosis; Working memory |
neuroleptic agent; acute psychosis; adolescent; adult; Article; attention; child; child psychiatry; clinical article; clinical assessment; clinical feature; controlled study; correlation analysis; cross-sectional study; digit span backward raw score; disease association; disease duration; duration of untreated psychosis; female; human; male; medical record; medication compliance; memory test; outcome assessment; patient compliance; pediatric patient; psychosis; schizophrenia; treatment duration; working memory |
Elsevier Inc. |
24681717 |
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Article |
#N/A |
#N/A |
#N/A |
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113 |
Tirtayasa P.M.W., Samuel A.G., Lisnawati, Retnowulan A. |
56245176500;57226642220;24449072000;57226640316; |
Parameatal glans cyst: A case report |
2021 |
Urology Case Reports |
39 |
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101802 |
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https://www.scopus.com/inward/record.uri?eid=2-s2.0-85112167978&doi=10.1016%2fj.eucr.2021.101802&partnerID=40&md5=a508fda307bc2bbe4ba2dcbc8048eb84 |
Department of Urology, Faculty of Medicine Universitas Udayana, Bali, Indonesia; Urology Consultant, Pelni General Hospital, Jakarta, Indonesia; Pathology Consultant, Pelni General Hospital, Jakarta, Indonesia; Department of Pathological Anatomy, Faculty of Medicine Universitas Indonesia, Jakarta, Indonesia |
Tirtayasa, P.M.W., Department of Urology, Faculty of Medicine Universitas Udayana, Bali, Indonesia; Samuel, A.G., Urology Consultant, Pelni General Hospital, Jakarta, Indonesia; Lisnawati, Pathology Consultant, Pelni General Hospital, Jakarta, Indonesia, Department of Pathological Anatomy, Faculty of Medicine Universitas Indonesia, Jakarta, Indonesia; Retnowulan, A., Pathology Consultant, Pelni General Hospital, Jakarta, Indonesia, Department of Pathological Anatomy, Faculty of Medicine Universitas Indonesia, Jakarta, Indonesia |
Parameatal glans cyst is unusual and only a few cases reported until currently. We presented a four-year-old boy with dysuria and inappropriate appearance of parameatal glans cyst. The cystic mass was slow-growing and was present since birth. Complete surgical excision was performed to prevent recurrencies and to achieve good cosmesis. © 2021 The Authors |
Glans cyst; Parameatal cyst; Urethral cyst |
Article; case report; child; clinical article; cuboidal epithelium; cyst; dysuria; epithelium; esthetic surgery; excision; follow up; general anesthesia; globular cystic swelling; histopathology; human; human tissue; male; parameatal glans cyst; penis glans; physical examination; preschool child; squamous epithelium; swelling; urethra; urethral meatus; urinalysis |
Elsevier Inc. |
22144420 |
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Article |
Q3 |
245 |
16962 |
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115 |
Meutia A.P., Yonathan K., Widia F. |
57203368133;57226144513;26028200800; |
Giant urethral caruncle resembling urethral prolapse causing outflow obstruction |
2021 |
Urology Case Reports |
39 |
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101783 |
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https://www.scopus.com/inward/record.uri?eid=2-s2.0-85110776549&doi=10.1016%2fj.eucr.2021.101783&partnerID=40&md5=01ebfd6f9c1caac70e9244d1c3ffe391 |
Division of Urogynecology and Reconstruction Department of Obstetrics and Gynecology, Faculty of Medicine, Universitas Indonesia, Dr. Cipto Mangunkusumo National General Hospital, Jakarta, Indonesia; Urogynecology Clinic, Bunda General Hospital, Jakarta, Indonesia; Faculty of Medicine, Universitas Indonesia, Dr. Cipto Mangunkusumo National General Hospital, Jakarta, Indonesia; Department of Urology, Faculty of Medicine, Universitas Indonesia, Dr. Cipto Mangunkusumo National General Hospital, Jakarta, Indonesia |
Meutia, A.P., Division of Urogynecology and Reconstruction Department of Obstetrics and Gynecology, Faculty of Medicine, Universitas Indonesia, Dr. Cipto Mangunkusumo National General Hospital, Jakarta, Indonesia, Urogynecology Clinic, Bunda General Hospital, Jakarta, Indonesia; Yonathan, K., Faculty of Medicine, Universitas Indonesia, Dr. Cipto Mangunkusumo National General Hospital, Jakarta, Indonesia; Widia, F., Department of Urology, Faculty of Medicine, Universitas Indonesia, Dr. Cipto Mangunkusumo National General Hospital, Jakarta, Indonesia |
Urethral caruncle is a rare condition primarily affecting elderly. Sometimes, it resembles urethral prolapse or malignancies. It can even cause outflow obstruction or urinary retention. A case of 83-years-old woman with urinary retention since a week prior was presented. Physical examination revealed a bulging mass originating from posterior lip of external urethral meatus. Due to the size, it caused outflow obstruction. The whole mass was excised. Histology examination reported the mass as urethral caruncle. Urethral caruncle is a common problem in elderly which rarely cause outflow obstruction. A thorough examination is required to distinguish it from malignancies and other disorders. © 2021 |
Pelvic organ prolapse; Urethral caruncle; Urethral disease |
aged; Article; blood cell count; case report; clinical article; female; general anesthesia; histology; histopathology; human; human tissue; pelvic examination; physical examination; postmenopause; urethra disease; urethra obstruction; urethral caruncle; urethral prolapse; urine retention; uroflowmetry; urothelium; vital sign |
Elsevier Inc. |
22144420 |
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Article |
Q3 |
245 |
16962 |
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116 |
Munadzilah S., Hegar B., Sekartini R., Vandenplas Y. |
57346126700;6506273944;57224503576;57223670656; |
Association between milk consumption and lactose malabsorption in Indonesian children |
2021 |
Chinese Journal of Contemporary Pediatrics |
23 |
10 |
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975 |
980 |
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https://www.scopus.com/inward/record.uri?eid=2-s2.0-85119440135&doi=10.7499%2fj.issn.1008-8830.2105030&partnerID=40&md5=80626db7ac7feaae0925a1057b4f77eb |
Department of Child Health, Faculty of Medicine Universitas Indonesia, Dr. Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Kidz Health Castle, UZ Brussel, Vrije Universiteit Brussel, Brussels, Belgium |
Munadzilah, S., Department of Child Health, Faculty of Medicine Universitas Indonesia, Dr. Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Hegar, B., Department of Child Health, Faculty of Medicine Universitas Indonesia, Dr. Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Sekartini, R., Department of Child Health, Faculty of Medicine Universitas Indonesia, Dr. Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Vandenplas, Y., Kidz Health Castle, UZ Brussel, Vrije Universiteit Brussel, Brussels, Belgium |
Objective To study the association between milk consumption and lactose malabsorption in Indonesian children aged 3-12 years. Methods This cross sectional study was conducted in randomly selected presumed healthy children with good nutritional status aged 3-12 years in Central Jakarta, Indonesia (n=174), including 72 children aged 3-5 years and 102 children aged 6-12 years. Results The prevalence of lactose malabsorption in children aged 3-5 years and children aged 6-12 years was 20.8% (15/72) and 35.3% (36/102), respectively. There was no association between milk or milk product consumption and lactose malabsorption (P>0.05). In the 51 children with lactose malabsorption, the predominant clinical symptoms were diarrhea (62%), abdominal pain (52%), and nausea (5%) during the hydrogen breath test. Conclusions There is no association between milk consumption and lactose malabsorption in Indonesian children aged 3-12 years, suggesting that genetic predisposition may be more important than adaptive mechanisms to lactose consumption. © 2021 Xiangya Hospital of CSU. All rights reserved. |
Child; Hydrogen breath test; Lactose malabsorption; Milk consumption; Prevalence |
abdominal pain; adult; Article; child; cross-sectional study; dairy product; diarrhea; disease association; female; genetic predisposition; human; hydrogen breath test; lactose intolerance; male; milk; nausea; prevalence; animal; breath analysis; Indonesia; lactose intolerance; milk; Animals; Breath Tests; Child; Cross-Sectional Studies; Humans; Indonesia; Lactose Intolerance; Milk |
Central South University |
10088830 |
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34719410 |
Article |
Q3 |
174 |
21112 |
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117 |
Umiatin, Indrasari W., Taryudi, Sari P., Mazfufah N.F., Rosadi I. |
57202292099;56069603500;57003576500;55776482300;57215595521;57204720098; |
Effect of pulse electromagnetic field exposure on the expression of lipo protein lipase (LPL) on the differentiation of mesenchymal stem cell |
2021 |
Journal of Physics: Conference Series |
2019 |
1 |
012107 |
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https://www.scopus.com/inward/record.uri?eid=2-s2.0-85119203085&doi=10.1088%2f1742-6596%2f2019%2f1%2f012107&partnerID=40&md5=cd764de9d9b9c1287f97fb09cfd8eea2 |
Department of Physics, Faculty of Mathematics and Natural Science, Universitas Negeri Jakarta, Indonesia; Department of Electronic Engineering, Faculty of Engineering, Universitas Negeri Jakarta, Indonesia; Department of Biology, Faculty of Medicine, Universitas Indonesia, Indonesia, Jl. Rawamangun Muka, Jakarta, 13220, Indonesia; Stem Cells and Tissue Engineering Research Center, IMERI, Faculty of Medicine, Universitas Indonesia, Indonesia; Department of Biology, Faculty of Mathematics and Natural Sciences, Mulawarman University, Samarinda, Indonesia |
Umiatin, Department of Physics, Faculty of Mathematics and Natural Science, Universitas Negeri Jakarta, Indonesia; Indrasari, W., Department of Physics, Faculty of Mathematics and Natural Science, Universitas Negeri Jakarta, Indonesia; Taryudi, Department of Electronic Engineering, Faculty of Engineering, Universitas Negeri Jakarta, Indonesia; Sari, P., Department of Biology, Faculty of Medicine, Universitas Indonesia, Indonesia, Jl. Rawamangun Muka, Jakarta, 13220, Indonesia; Mazfufah, N.F., Stem Cells and Tissue Engineering Research Center, IMERI, Faculty of Medicine, Universitas Indonesia, Indonesia; Rosadi, I., Department of Biology, Faculty of Mathematics and Natural Sciences, Mulawarman University, Samarinda, Indonesia |
Pulsed electromagnetic fields (PEMFs) have an important role in cell differentiation. Previous study reported that PEMFs had positive and negative effect towards cell differentiation that depends on their frequencies applied to the cells. Human adipose-derived stem cells (ASCs) are mesenchymal stem cells that have an ability to differentiate into several types of cell including adipocytes, chondrocytes and osteocytes. This study aimed to evaluate the effect of human ASCs towards their adipogenic differentiation during PEMFs exposure. Human ASCs were isolated from adipose tissue. The cells then cultured in specific medium of adipocyte that induced ASCs differentiation along with PEMFs exposure. The maximum magnetic field used is 2 mT with a frequency of 75 Hz. To confirm the effect of PEMFs exposure towards adipogenic differentiation, mRNA expression of lipo protein lipase (LPL) was measured in mRNA expression level. The results showed that ASCs cultured on adipogenic differentiation without PEMFs exposure gradually increased LPL expression until day 14 of observation, while ASCs with PEMFs exposure significantly decreased LPL expression from day 2 to day 14. Based on the results, we concluded that PEMFs exposure can inhibit LPL expression that suppressed adipogenic differentiation. © 2021 Institute of Physics Publishing. All rights reserved. |
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Electromagnetic field effects; Electromagnetic fields; Proteins; Stem cells; Adipogenic differentiations; Adipose derived stem cells; Cell differentiation; Cell-be; Cell/B.E; Electromagnetic field exposure; Human adipose; Lipo proteins; Mesenchymal stem cell; Pulsed electromagnetic fields; Cell culture |
IOP Publishing Ltd |
17426588 |
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Conference Paper |
Q4 |
210 |
18731 |
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119 |
Parikesit D., Adityagama M., Atmoko W., Birowo P., Taher A., Rasyid N. |
57163830300;57328473300;57193125664;6504153311;7005269743;56245069300; |
Reliability and validity of the Indonesian version of the aging males’ symptoms |
2021 |
Medical Journal of Indonesia |
30 |
3 |
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211 |
214 |
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https://www.scopus.com/inward/record.uri?eid=2-s2.0-85118800087&doi=10.13181%2fmji.oa.215314&partnerID=40&md5=de2f7f19ff7768cc59e6ab7817803329 |
Department of Urology, Faculty of Medicine, Universitas Indonesia, Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Department of Urology, Faculty of Medicine, Universitas Indonesia, Universitas Indonesia Hospital, Depok, Indonesia |
Parikesit, D., Department of Urology, Faculty of Medicine, Universitas Indonesia, Cipto Mangunkusumo Hospital, Jakarta, Indonesia, Department of Urology, Faculty of Medicine, Universitas Indonesia, Universitas Indonesia Hospital, Depok, Indonesia; Adityagama, M., Department of Urology, Faculty of Medicine, Universitas Indonesia, Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Atmoko, W., Department of Urology, Faculty of Medicine, Universitas Indonesia, Cipto Mangunkusumo Hospital, Jakarta, Indonesia, Department of Urology, Faculty of Medicine, Universitas Indonesia, Universitas Indonesia Hospital, Depok, Indonesia; Birowo, P., Department of Urology, Faculty of Medicine, Universitas Indonesia, Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Taher, A., Department of Urology, Faculty of Medicine, Universitas Indonesia, Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Rasyid, N., Department of Urology, Faculty of Medicine, Universitas Indonesia, Cipto Mangunkusumo Hospital, Jakarta, Indonesia |
BACKGROUND Aging males’ symptoms (AMS) scale was developed to study the problems of aging males, especially related to the quality of life. Currently, there is no valid and reliable Indonesian version of the AMS scale. This study was aimed to translate and evaluate the validity and reliability of the Indonesian version of the AMS scale. METHODS This cross-sectional study translated the existing AMS scale into Indonesian, which was tested in 40 years old males from May to August 2020. Cross-cultural validation of the AMS scale was conducted by translating the questionnaire from English to Indonesian by two independent-certified translators. The validity of the Indonesian version of the AMS scale was measured by conducting a Pearson correlation (r) analysis. The reliability of this questionnaire was tested and retested in 118 participants with a 2-week interval. In addition, Cronbach’s alpha value was measured and used as a reference. The first test was conducted in a corporate blood donor event in Matraman, East Jakarta, and the retest was conducted in Cipto Mangunkusumo Hospital. RESULTS The Indonesian version of the AMS scale was valid and had a good internal consistency with a Cronbach’s alpha value of 0.74. The test-retest reliability showed good reliability with an r-value of 0.981. Pearson correlation test showed that all questions in the questionnaire were valid (p<0.05) and correlated positively. CONCLUSIONS The Indonesian version of the AMS scale derived from this study is valid and has good reliability. © 2021, Faculty of Medicine, Universitas Indonesia. All rights reserved. |
Aging males’ symptoms scale; Indonesian; Reliability and validity |
adult; aging; article; blood donor; Cronbach alpha coefficient; cross-sectional study; human; human experiment; internal consistency; language; major clinical study; male; questionnaire; test retest reliability; validity |
Faculty of Medicine, Universitas Indonesia |
08531773 |
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Article |
Q4 |
164 |
21905 |
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120 |
Soedarman S., Rahardjo H.E. |
57220581938;37762030000; |
Potential predictors of detrusor underactivity in a urology outpatient clinic: A 5-year single center experience study |
2021 |
Medical Journal of Indonesia |
30 |
3 |
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https://www.scopus.com/inward/record.uri?eid=2-s2.0-85118768336&doi=10.13181%2fmji.oa.215102&partnerID=40&md5=8286bb60fbc23a9907af0545c3ad23c0 |
Department of Urology, Faculty of Medicine, Universitas Indonesia, Cipto Mangunkusumo Hospital, Jakarta, Indonesia |
Soedarman, S., Department of Urology, Faculty of Medicine, Universitas Indonesia, Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Rahardjo, H.E., Department of Urology, Faculty of Medicine, Universitas Indonesia, Cipto Mangunkusumo Hospital, Jakarta, Indonesia |
BACKGROUND Detrusor underactivity (DU) is diagnosed using urodynamics, which caused by a combination of strength and duration of the bladder muscle and resulted in prolonged bladder emptying. Invasive urodynamics, which are limited in many clinical settings, should be performed efficiently in high-risk patients to reduce the risk of emerging complications during and after the procedure. Therefore, this study was aimed to identify the potential predictors of DU for limited clinical settings. METHODS This retrospective study was retrieved from the medical records of patients who underwent urodynamics in the Department of Urology, Cipto Mangunkusumo Hospital from 2015 to 2020. Age, sex, bladder capacity, bladder compliance, bladder outlet obstruction, history of stroke, diabetes mellitus (DM) status, and neurological abnormalities were analyzed using chi-square and Mann–Whitney to examine the potential predictors of DU. The odds ratio (OR) of each factor was also calculated. Logistic regression was furtherly used for the analysis. RESULTS A total of 649 patients were included in this study. Male (OR = 1.74, 95% CI = 1.28–2.38) and DM patients (OR = 2.06, 95% CI = 1.36–3.11) had a higher risk of DU, while bladder outlet obstruction (OR = 0.54, 95% CI = 0.39–0.76) was the protective factor of DU. Furthermore, multivariate analysis showed that the potential predictors of DU were male (OR = 1.903, 95% CI = 1.37–2.64), DM (OR= 1.899, 95% CI = 1.22–2.95), and bladder outlet obstruction (OR = 0.32, 95% CI = 0.32–0.65). CONCLUSIONS Age, sex, bladder outlet obstruction, and history of DM could become the predictors of DU. © 2021, Faculty of Medicine, Universitas Indonesia. All rights reserved. |
Detrusor underactivity; Urinary bladder; Urodynamics |
adolescent; adult; age; aged; Article; bladder capacity; bladder compliance; bladder pressure; child; diabetes mellitus; diabetic patient; human; hypotonic bladder; major clinical study; male; neurologic disease; overactive bladder; sex; software; urodynamics |
Faculty of Medicine, Universitas Indonesia |
08531773 |
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