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669 |
Syafira N., Graudins A., Yarema M., Wong A. |
57222178056;55790181600;8550407600;52265101200; |
Comparing development of liver injury using the two versus three bag acetylcysteine regimen despite early treatment in paracetamol overdose |
2021 |
Clinical Toxicology |
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https://www.scopus.com/inward/record.uri?eid=2-s2.0-85119253032&doi=10.1080%2f15563650.2021.1998518&partnerID=40&md5=71ecde369075113c2b3f41b9bb20e452 |
Department of Medicine, School of Clinical Science at Monash Health, Monash UniversityVIC, Australia; Faculty of Medicine, Universitas Indonesia, Special Capital Region of Jakarta, Indonesia; Monash Toxicology Unit, Dandenong Hospital, Monash HealthVIC, Australia; Poison and Drug Information Service, Alberta Health Services, Calgary, Canada; Department of Emergency Medicine, University of Calgary, Calgary, Canada; Austin Toxicology Unit, Austin HealthVIC, Australia; Department of Critical Care, University of MelbourneVIC, Australia |
Syafira, N., Department of Medicine, School of Clinical Science at Monash Health, Monash UniversityVIC, Australia, Faculty of Medicine, Universitas Indonesia, Special Capital Region of Jakarta, Indonesia; Graudins, A., Department of Medicine, School of Clinical Science at Monash Health, Monash UniversityVIC, Australia, Monash Toxicology Unit, Dandenong Hospital, Monash HealthVIC, Australia; Yarema, M., Poison and Drug Information Service, Alberta Health Services, Calgary, Canada, Department of Emergency Medicine, University of Calgary, Calgary, Canada; Wong, A., Department of Medicine, School of Clinical Science at Monash Health, Monash UniversityVIC, Australia, Austin Toxicology Unit, Austin HealthVIC, Australia, Department of Critical Care, University of MelbourneVIC, Australia |
Introduction: Some studies have reported that early administration of acetylcysteine using a 3-bag regimen may not fully prevent development of liver injury in some patients. We compared the incidence of acute liver injury (ALI) in patients receiving acetylcysteine within eight hours of ingestion between the two-bag acetylcysteine regimen (200 mg/kg over four hours, 100 mg/kg over 16 h) and the three-bag regimen (150 mg/kg over 1 h, 50 mg/kg over 4 h, 100 mg/kg over 16 h). Method: This was a retrospective cohort study of the two-bag and three-bag acetylcysteine regimens from Monash Health, Victoria, Australia (2009–2020), compared to the three-bag acetylcysteine regimen data from the Canadian Acetaminophen Overdose Study (CAOS) database (1980–2005). The inclusion criteria included patients with an acute single ingestion of paracetamol; normal aminotransferases on presentation and acetylcysteine administered within eight hours post-overdose. The primary outcome was development of ALI (defined as: peak aminotransferase >150 IU/L). Results: At Monash Health, 191 patients were treated with the two-bag acetylcysteine regimen, and 180 patients with the three-bag regimen. The CAOS cohort provided 515 patients treated with the three-bag regimen. ALI developed in 1.6% (3/191) of the two-bag Monash Health group, 2.2% (4/180) of the three-bag Monash Health group (difference −0.6%, p 0.7), and 2.9% (15/515) of the three-bag CAOS group (difference compared to two-bag −1.3%, p 0.4). Hepatotoxicity (ALT >1000) developed in 0.5% (1/191) of patients treated with the two-bag regimen, 1.7% (3/180) in the Monash Health three-bag regimen and 1% (5/515) of the three-bag CAOS group. There were no statistically significant differences between groups. Conclusions: ALI and hepatotoxicity were observed in a small, comparable percentage of patients despite early acetylcysteine administration using the two-bag and three-bag regimens. Repeating blood tests at the end of acetylcysteine treatment will identify these patients and indicate those requiring continuation of acetylcysteine. © 2021 Informa UK Limited, trading as Taylor & Francis Group. |
Acetaminophen; acute liver injury; hepatotoxicity |
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Taylor and Francis Ltd. |
15563650 |
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Article |
Q2 |
840 |
5641 |
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678 |
Sulistio S., Habib H., Mulyana R.M., Albar I.A. |
57216916380;57216916669;57216915765;57216915796; |
Emergency intubation practices in a tertiary teaching hospital in Jakarta, Indonesia: A prospective observational study |
2021 |
EMA - Emergency Medicine Australasia |
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https://www.scopus.com/inward/record.uri?eid=2-s2.0-85118592756&doi=10.1111%2f1742-6723.13890&partnerID=40&md5=f148a4a939c1e802197c4a35882c3a66 |
Emergency Department, Cipto Mangunkusumo General Hospital, Jakarta, Indonesia; Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia |
Sulistio, S., Emergency Department, Cipto Mangunkusumo General Hospital, Jakarta, Indonesia, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Habib, H., Emergency Department, Cipto Mangunkusumo General Hospital, Jakarta, Indonesia, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Mulyana, R.M., Emergency Department, Cipto Mangunkusumo General Hospital, Jakarta, Indonesia, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Albar, I.A., Emergency Department, Cipto Mangunkusumo General Hospital, Jakarta, Indonesia, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia |
Objective: Intubation is an important competency for emergency doctors. Emergency patients are often unstable, with undifferentiated conditions. There is little time to prepare these patients prior to intubation and so ED intubation may differ from intubation in intensive care units and operating theatres. The present study aims to describe the characteristics of emergency intubation after an administrative policy change within a tertiary teaching hospital in Jakarta, allowing non-anaesthetists to perform intubation in the ED. Methods: Prospective data were collected regarding patients of all age groups who were intubated at the ED of Cipto Mangunkusumo General Hospital, Jakarta, from February 2018 to January 2019. Patient characteristics, intubation attempts, medications used, complications, and disposition were recorded in a self-reported airway registry based on the Australian and New Zealand Emergency Department Airway Registry (ANZEDAR) form. Results: During the 12-month study period, 231 patients, or 41.5% of ED intubated patients were enrolled in the study, and there were 268 intubation attempts on these enrolled patients. The first-pass success rate was 207 out of 231 patients, or 89.6%, with anaesthetist (88.9%), better than emergency doctors (55.4%). Complications were reported in 51 patients, or 22.0%, with desaturation and hypotension being the most common. Thirty-three patients, or 14.3%, died in the ED before being transferred to another unit. Conclusions: The first-pass success rate is comparable with international data. Non-anaesthetic physicians must improve their experience to achieve a favourable success rate. The data on complications highlight the need for improvement in Indonesian ED intubation practices. © 2021 Australasian College for Emergency Medicine |
airway complications; airway management; emergency medicine; rapid sequence intubation; registry |
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John Wiley and Sons Inc |
17426731 |
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Article |
Q2 |
602 |
8388 |
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680 |
Sandora N., Putra M.A., Nurhayati R.W., Suwarti, Nauli R., Kusuma T.R., Fitria N.A., Ardiansyah, Muttaqin C., Makdinata W., Alwi I. |
57204103434;57215605850;55748436600;57212462722;57212478305;57222897694;57148498800;57223036386;57226442135;57223405655;15055173800; |
Characterisation of the single-cell human cardiomyocytes taken from the excess heart tissue of the right ventricular outlet in congenital heart disease |
2021 |
Cell and Tissue Banking |
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https://www.scopus.com/inward/record.uri?eid=2-s2.0-85118214107&doi=10.1007%2fs10561-021-09970-4&partnerID=40&md5=2c4fad90958206777aa1ef5e9ea1e5ec |
Faculty of Medicine, Universitas Riau, Pekanbaru, 28293, Indonesia; Indonesia Medical Education and Research Institute, Jakarta, 10430, Indonesia; Faculty of Medicine, Universitas Indonesia, Jakarta, 10430, Indonesia |
Sandora, N., Faculty of Medicine, Universitas Riau, Pekanbaru, 28293, Indonesia, Indonesia Medical Education and Research Institute, Jakarta, 10430, Indonesia; Putra, M.A., Faculty of Medicine, Universitas Indonesia, Jakarta, 10430, Indonesia; Nurhayati, R.W., Indonesia Medical Education and Research Institute, Jakarta, 10430, Indonesia; Suwarti, Indonesia Medical Education and Research Institute, Jakarta, 10430, Indonesia; Nauli, R., Indonesia Medical Education and Research Institute, Jakarta, 10430, Indonesia; Kusuma, T.R., Indonesia Medical Education and Research Institute, Jakarta, 10430, Indonesia; Fitria, N.A., Indonesia Medical Education and Research Institute, Jakarta, 10430, Indonesia; Ardiansyah, Faculty of Medicine, Universitas Indonesia, Jakarta, 10430, Indonesia; Muttaqin, C., Faculty of Medicine, Universitas Indonesia, Jakarta, 10430, Indonesia; Makdinata, W., Faculty of Medicine, Universitas Indonesia, Jakarta, 10430, Indonesia; Alwi, I., Faculty of Medicine, Universitas Indonesia, Jakarta, 10430, Indonesia |
Cardiovascular disease is the second highest cause of death across the globe. Myocardial infarction is one of the heart diseases that cause permanent impairment of the heart wall leads to heart failure. Cellular therapy might give hope to regenerate the damaged myocardium. Single cells isolated from an excess heart tissue obtained from the correction of the right ventricular hypertrophy in patients with Tetralogy of Fallot for future heart study were investigated. Methods: Once resected, the heart tissues were transported at 37 °C, in Dulbecco's Modified Eagle's medium/ DMEM (4.5 g.L−1, antibiotic–antimycotic 3x, PRP10% (v/v)), to reach the lab within 30 min, weighted and grouped into less than 500 mg and more than 1000 mg (n = 4). Each sample was digested with 250 U.mL−1 Collagenase type V and 4U.mL−1 Proteinase XXIV in the MACS™ C-tube (Milltenyi, Germany), then dissociated using the MACS™ Octo Dissociator with Heater (Milltenyi, Germany) for 60 min at 37 °C. Results: All cells isolated were rod-shaped cells; viability was up to 90%. The cell density obtained from the 500 mg group were 4,867 ± 899 cells.mg−1 tissue weight, significantly higher compared to the 1,000 mg group; had 557 ± 490 cells.mg−1 tissue weight (mean of (n = 3) ± 95% C.l). The isolated cells were analyzed using FACs BD Flowcytometer, expressed cTnT + 13.38%, PECAM-1 + /VCAM-1- 32.25%, cKit + 7.85%, ICAM + 85.53%, indicating the cardiomyocyte progenitor cells. Conclusion: Cardiomyocytes taken from the wasted heart tissue might be a candidate of cardiomyocytes source to study interventions to the heart as it contained up to 13.38% cardiomyocytes, and 32.25% of cardiac progenitor cells. Moreover, perhaps when cardiac cell therapy needs autologous cardiomyocytes, less than 500 mg tissue weight can be considered as sufficient. © 2021, The Author(s), under exclusive licence to Springer Nature B.V. |
Cardiac progenitor cells; Cardiomyocyte isolation; Right ventricular resection; Tetralogy of fallot; Waste heart tissue |
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Springer Science and Business Media B.V. |
13899333 |
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Article |
Q3 |
397 |
12196 |
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692 |
Harapan H., Fajar J.K., Supriono S., Soegiarto G., Wulandari L., Seratin F., Prayudi N.G., Dewi D.P., Monica Elsina M.T., Atamou L., Wiranata S., Aprianto D.P., Friska E., Sari Firdaus D.F., Alaidin M., Wardhani F.A., Husnah M., Hidayati N.W., Hendriyanti Y., Wardani K., Evatta A., Manugan R.A., Pradipto W., Rahmawati A., Tamara F., Mahendra A.I., Nainu F., Santoso B., Irawan Primasatya C.A., Tjionganata N., Budiman H.A. |
55844857500;56156139600;57218591523;57193717004;52464692000;57291538600;57291762600;57291994900;57291762700;57292451200;57220591122;57292451300;57291762800;57292675300;57291538700;57291315100;57194724156;57291315200;57292218900;57292909500;57292451400;57292219000;57292219100;57292675400;57192950403;57202301766;57120069200;57291762900;57291995000;57291538800;57291763000; |
The prevalence, predictors and outcomes of acute liver injury among patients with COVID-19: A systematic review and meta-analysis |
2021 |
Reviews in Medical Virology |
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https://www.scopus.com/inward/record.uri?eid=2-s2.0-85116888408&doi=10.1002%2frmv.2304&partnerID=40&md5=8da649362695a47bd93802e3d5061df1 |
Medical Research Unit, School of Medicine, Universitas Syiah Kuala, Banda Aceh, Indonesia; Tropical Disease Centre, School of Medicine, Universitas Syiah Kuala, Banda Aceh, Indonesia; Department of Microbiology, School of Medicine, Universitas Syiah Kuala, Banda Aceh, Indonesia; Brawijaya Internal Medicine Research Centre, Department of Internal Medicine, Faculty of Medicine, Universitas Brawijaya, Malang, Indonesia; Department of Internal Medicine, Division of Gastro-Entero-Hepatology, Faculty of Medicine, Universitas Brawijaya, Malang, Indonesia; Department of Internal Medicine, Division of Allergy & Immunology, Universitas Airlangga, Surabaya, Indonesia; Department of Pulmonology and Respiratory Medicine, Universitas Airlangga, Surabaya, Indonesia; Department of Paediatric, Faculty of Medicine, Universitas Padjajaran, Bandung, Indonesia; Department of Urology, Faculty of Medicine, Universitas Brawijaya, Malang, Indonesia; Faculty of Public Health, Universitas Indonesia, Depok, Indonesia; Faculty of Nursing, Universitas Indonesia, Depok, Indonesia; Faculty of Medicine, Universitas Udayana, Denpasar, Indonesia; Faculty of Medicine, Universitas Indonesia, Depok, Indonesia; Department of Nursing, Faculty of Medicine, Universitas Diponegoro, Semarang, Indonesia; Faculty of Medicine, Universitas Gadjah Mada, Yogyakarta, Indonesia; Master Program of Biology, Faculty of Mathematics and Natural Sciences, Universitas Syiah Kuala, Banda Aceh, Indonesia; Faculty of Pharmacy, Hasanuddin University, Makassar, Indonesia; Department of Internal Medicine, RSUD Bangil, Pasuruan, Indonesia; Faculty of Medicine, Universitas Airlangga, Surabaya, Indonesia; Department of Internal Medicine, Faculty of Medicine, Universitas Airlangga, Surabaya, Indonesia |
Harapan, H., Medical Research Unit, School of Medicine, Universitas Syiah Kuala, Banda Aceh, Indonesia, Tropical Disease Centre, School of Medicine, Universitas Syiah Kuala, Banda Aceh, Indonesia, Department of Microbiology, School of Medicine, Universitas Syiah Kuala, Banda Aceh, Indonesia; Fajar, J.K., Brawijaya Internal Medicine Research Centre, Department of Internal Medicine, Faculty of Medicine, Universitas Brawijaya, Malang, Indonesia; Supriono, S., Department of Internal Medicine, Division of Gastro-Entero-Hepatology, Faculty of Medicine, Universitas Brawijaya, Malang, Indonesia; Soegiarto, G., Department of Internal Medicine, Division of Allergy & Immunology, Universitas Airlangga, Surabaya, Indonesia; Wulandari, L., Department of Pulmonology and Respiratory Medicine, Universitas Airlangga, Surabaya, Indonesia; Seratin, F., Department of Paediatric, Faculty of Medicine, Universitas Padjajaran, Bandung, Indonesia; Prayudi, N.G., Department of Urology, Faculty of Medicine, Universitas Brawijaya, Malang, Indonesia; Dewi, D.P., Faculty of Public Health, Universitas Indonesia, Depok, Indonesia; Monica Elsina, M.T., Faculty of Nursing, Universitas Indonesia, Depok, Indonesia; Atamou, L., Faculty of Nursing, Universitas Indonesia, Depok, Indonesia; Wiranata, S., Faculty of Medicine, Universitas Udayana, Denpasar, Indonesia; Aprianto, D.P., Faculty of Public Health, Universitas Indonesia, Depok, Indonesia; Friska, E., Faculty of Medicine, Universitas Indonesia, Depok, Indonesia; Sari Firdaus, D.F., Faculty of Medicine, Universitas Indonesia, Depok, Indonesia; Alaidin, M., Department of Nursing, Faculty of Medicine, Universitas Diponegoro, Semarang, Indonesia; Wardhani, F.A., Faculty of Medicine, Universitas Gadjah Mada, Yogyakarta, Indonesia; Husnah, M., Master Program of Biology, Faculty of Mathematics and Natural Sciences, Universitas Syiah Kuala, Banda Aceh, Indonesia; Hidayati, N.W., Faculty of Medicine, Universitas Gadjah Mada, Yogyakarta, Indonesia; Hendriyanti, Y., Faculty of Medicine, Universitas Gadjah Mada, Yogyakarta, Indonesia; Wardani, K., Brawijaya Internal Medicine Research Centre, Department of Internal Medicine, Faculty of Medicine, Universitas Brawijaya, Malang, Indonesia; Evatta, A., Brawijaya Internal Medicine Research Centre, Department of Internal Medicine, Faculty of Medicine, Universitas Brawijaya, Malang, Indonesia; Manugan, R.A., Brawijaya Internal Medicine Research Centre, Department of Internal Medicine, Faculty of Medicine, Universitas Brawijaya, Malang, Indonesia; Pradipto, W., Brawijaya Internal Medicine Research Centre, Department of Internal Medicine, Faculty of Medicine, Universitas Brawijaya, Malang, Indonesia; Rahmawati, A., Brawijaya Internal Medicine Research Centre, Department of Internal Medicine, Faculty of Medicine, Universitas Brawijaya, Malang, Indonesia; Tamara, F., Brawijaya Internal Medicine Research Centre, Department of Internal Medicine, Faculty of Medicine, Universitas Brawijaya, Malang, Indonesia; Mahendra, A.I., Brawijaya Internal Medicine Research Centre, Department of Internal Medicine, Faculty of Medicine, Universitas Brawijaya, Malang, Indonesia; Nainu, F., Faculty of Pharmacy, Hasanuddin University, Makassar, Indonesia; Santoso, B., Department of Internal Medicine, RSUD Bangil, Pasuruan, Indonesia; Irawan Primasatya, C.A., Faculty of Medicine, Universitas Airlangga, Surabaya, Indonesia; Tjionganata, N., Department of Internal Medicine, Faculty of Medicine, Universitas Airlangga, Surabaya, Indonesia; Budiman, H.A., Faculty of Medicine, Universitas Airlangga, Surabaya, Indonesia |
The data on the predictors and prognosis of acute liver injury (ALI) among patients in coronavirus disease 2019 (COVID-19) patients are limited. The aim of this study was to determine the prevalence, predictors and outcomes of ALI among patients with COVID-19. A systematic review was conducted up to 10 June 2021. The relevant papers were searched from PubMed, Embase, Cochrane and Web of Science, and the data were analysed using a Z test. A total of 1331 papers were identified and 16 papers consisting of 1254 COVID-19 with ALI and 4999 COVID-19 without ALI were analysed. The cumulative prevalence of ALI among patients with COVID-19 was 22.8%. Male and having low lymphocyte levels were more likely to be associated with ALI compared with female and having higher lymphocyte level, odds ratio (OR): 2.70; 95% confidence interval (CI): 2.03, 3.60 and mean difference (MD) −125; 95% CI: −207, −43, respectively. COVID-19 patients with ALI had higher risk of developing severe COVID-19 compared with those without ALI (OR: 3.61; 95% CI: 2.60, 5.02). Our findings may serve as the additional evaluation for the management of ALI in COVID-19 patients. © 2021 John Wiley & Sons Ltd. |
acute liver injury; COVID-19; outcome; predictor; prevalence |
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John Wiley and Sons Ltd |
10529276 |
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Review |
Q1 |
2060 |
1246 |
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695 |
Adiarto S., Kurnianingsih N., Prasetya I., Nugroho F.W., Uberoi R. |
8603606800;57223044495;56725585200;57290221600;22136581000; |
Successful Primary PCI in Stanford Type A Aortic Dissection Complicated by Inferior ST-Elevation Myocardial Infarction: A Case in a Facility with No Surgical Backup |
2021 |
International Journal of Angiology |
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https://www.scopus.com/inward/record.uri?eid=2-s2.0-85116762000&doi=10.1055%2fs-0041-1735205&partnerID=40&md5=3716852a47a6df47d93b73adfb8623d6 |
Department of Cardiology and Vascular Medicine, Faculty of Medicine, Universitas Indonesia, Harapan Kita National Cardiovascular Center, Jl. Letjen S. Parman Kav. 87 Slipi, Jakarta, 11420, Indonesia; Department of Cardiology and Vascular Medicine, Faculty of Medicine Brawijaya University, Dr. Saiful Anwar Hospital, East Java, Malang, Indonesia; Department of Radiology, John Radcliffe Hospital, Headington, Oxford, United Kingdom |
Adiarto, S., Department of Cardiology and Vascular Medicine, Faculty of Medicine, Universitas Indonesia, Harapan Kita National Cardiovascular Center, Jl. Letjen S. Parman Kav. 87 Slipi, Jakarta, 11420, Indonesia; Kurnianingsih, N., Department of Cardiology and Vascular Medicine, Faculty of Medicine Brawijaya University, Dr. Saiful Anwar Hospital, East Java, Malang, Indonesia; Prasetya, I., Department of Cardiology and Vascular Medicine, Faculty of Medicine Brawijaya University, Dr. Saiful Anwar Hospital, East Java, Malang, Indonesia; Nugroho, F.W., Department of Cardiology and Vascular Medicine, Faculty of Medicine Brawijaya University, Dr. Saiful Anwar Hospital, East Java, Malang, Indonesia; Uberoi, R., Department of Radiology, John Radcliffe Hospital, Headington, Oxford, United Kingdom |
Mortality of type A aortic dissection (TAAD) complicated with coronary malperfusion syndrome is very high even when emergency surgery is performed. Several reports suggested that primary percutaneous coronary intervention (PPCI) followed by immediate corrective surgery may reduce mortality. In many countries, immediate transfer to an aortic surgery center may not be possible. We report a case of TAAD complicated by coronary malperfusion successfully treated with PPCI followed by elective corrective surgery. A 48-year-old man was referred to emergency department with acute inferior ST-elevation myocardial infarction (STEMI) and underwent PPCI. During the procedure, we realized that the cause of STEMI was TAAD. We decided to continue because the patient experienced seizures and bradycardia. Subsequently, echocardiography and computed tomography confirmed the dissection. The patient was discharged and referred to the National Cardiovascular Center where he underwent successful elective surgery. In this patient, immediate revascularization was lifesaving and served as a bridging procedure before surgical correction. © 2021 Georg Thieme Verlag. All rights reserved. |
aortic dissection; coronary intervention; coronary malperfusion syndrome; malperfusion syndrome; primary PCI; STEMI; type A aortic dissection |
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Thieme Medical Publishers, Inc. |
10611711 |
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Article |
Q3 |
293 |
15070 |
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696 |
Nugraha R.A., Muliawan H.S., Nugroho N.T., Ikhsan M., Adiarto S. |
57220785065;57203644653;57211452795;57291104400;8603606800; |
Catastrophic Concomitant Arterial and Venous Thrombosis in a Mild COVID-19-Positive Patient |
2021 |
International Journal of Angiology |
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https://www.scopus.com/inward/record.uri?eid=2-s2.0-85116737806&doi=10.1055%2fs-0041-1735200&partnerID=40&md5=35939b91c7ecfee83d98ad94c4b7e884 |
Department of General Medicine, Universitas Indonesia Hospital, Universitas Indonesia, Jl. Prof Bahder Djohan, Pondok Cina, Beji, Depok, 16424, Indonesia; Department of Cardiology and Vascular Medicine, National Cardiovascular Center Harapan Kita, Universitas Indonesia Hospital, Depok, Indonesia; Department of Vascular and Endovascular Surgery, Cipto Mangunkusumo Hospital, Universitas Indonesia Hospital, Depok, Indonesia; Department of Internal Medicine, Cipto Mangunkusumo Hospital, Universitas Indonesia Hospital, Depok, Indonesia |
Nugraha, R.A., Department of General Medicine, Universitas Indonesia Hospital, Universitas Indonesia, Jl. Prof Bahder Djohan, Pondok Cina, Beji, Depok, 16424, Indonesia; Muliawan, H.S., Department of Cardiology and Vascular Medicine, National Cardiovascular Center Harapan Kita, Universitas Indonesia Hospital, Depok, Indonesia; Nugroho, N.T., Department of Vascular and Endovascular Surgery, Cipto Mangunkusumo Hospital, Universitas Indonesia Hospital, Depok, Indonesia; Ikhsan, M., Department of Internal Medicine, Cipto Mangunkusumo Hospital, Universitas Indonesia Hospital, Depok, Indonesia; Adiarto, S., Department of Cardiology and Vascular Medicine, National Cardiovascular Center Harapan Kita, Universitas Indonesia Hospital, Depok, Indonesia |
Since its first discovery in late 2019, coronavirus disease 2019 (COVID-19) has been a global burden associated with significant morbidity and mortality. COVID-19 has been correlated with the development of hypercoagulable state that predisposes the patients to a higher risk of thromboembolism. Current evidence suggests higher incidence of thrombosis, particularly venous thrombosis, among hospitalized COVID-19 patients, mostly with critical illness. On the other hand, there is currently no data regarding the incidence of vivid thrombosis in ambulatory patients with mild COVID-19 and the incidence of concomitant arterial and venous thrombosis in COVID-19 is extremely rare. Herein, we describe catastrophic outcomes of concomitant lower limb arterial and venous thrombosis in a patient with mild COVID-19. This report highlights the occurrence of concomitant arterial and venous thrombosis in ambulatory setting and that this phenomenon resulted in catastrophic clinical consequences. © 2021 Georg Thieme Verlag. All rights reserved. |
acute limb ischemia; ambulatory; anticoagulation; deep vein thrombosis; ischemia-reperfusion injury; mild COVID-19; thrombectomy |
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Thieme Medical Publishers, Inc. |
10611711 |
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Article |
Q3 |
293 |
15070 |
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699 |
Putri K.T., Prasetyono T.O.H. |
57205299147;26646993900; |
A critical review on the potential role of adipose-derived stem cells for future treatment of hypertrophic scars |
2021 |
Journal of Cosmetic Dermatology |
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1 |
https://www.scopus.com/inward/record.uri?eid=2-s2.0-85116423050&doi=10.1111%2fjocd.14385&partnerID=40&md5=76adc3d0cee033ca6ae3fe7ec706fe72 |
Undergraduate Study Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Division of Plastic Surgery, Department of Surgery, Cipto Mangunkusumo Hospital/Faculty of Medicine Universitas Indonesia, Jakarta, Indonesia |
Putri, K.T., Undergraduate Study Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Prasetyono, T.O.H., Division of Plastic Surgery, Department of Surgery, Cipto Mangunkusumo Hospital/Faculty of Medicine Universitas Indonesia, Jakarta, Indonesia |
Introduction: Adipose-derived stem cells (ASCs) have recently gained researchers’ interest as a solution to various diseases and conditions, including hypertrophic scar. This literature review aims to elucidate ASCs as a potential solution to alleviate hypertrophic scar in human subjects. Methods: Literature search was done in databases which includes PubMed, MEDLINE, and ProQuest using terms ‘adipose derived stem cells’, ‘adipose cells’, ‘fat graft’, ‘fat grafting’, ‘autologous fat graft’, ‘fat injection’, ‘lipofilling’, ‘scar management’, ‘scar treatment’, ‘burn scar’, and ‘wound management’. The included articles which were published during year 2000-November 2020 must describe the use of ASCs or fat grafting or lipofilling as an attempt to alleviate hypertrophic scar. Remarks: Clinically, ASCs improve hypertrophic scars in terms of scar color, elasticity, texture, thickness, and size. Histologically, ASCs promotes healthy tissue regeneration, reduction in fibroblasts, and reorganisation of collagen, resembling those of normal skin. In terms of molecular aspects, ASCs alleviates hypertrophic scars through direct differentiation and paracrine mechanisms. Conclusion: Adipose-derived stem cells, emerge to be a potential solution for alleviating hypertrophic scar, as demonstrated in various studies. However, there has been no studies conducted in human subjects to investigate the effect of ASCs on hypertrophic scar. © 2021 Wiley Periodicals LLC |
adipocytes; cicatrix; fibroblast; intercellular signaling peptides and proteins; stem cells |
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John Wiley and Sons Inc |
14732130 |
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Review |
Q2 |
626 |
8066 |
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703 |
Massenburg B.B., Hopper R.A., Crowe C.S., Morrison S.D., Alonso N., Calis M., Donkor P., Kreshanti P., Yuan J. |
55859007400;57277146200;55976347800;45661573100;7004026436;53263345100;15063876600;36192866200;57278294200; |
Global Burden of Orofacial Clefts and the World Surgical Workforce |
2021 |
Plastic and Reconstructive Surgery |
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568E |
580E |
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1 |
https://www.scopus.com/inward/record.uri?eid=2-s2.0-85115936193&doi=10.1097%2fPRS.0000000000008334&partnerID=40&md5=b6aab0e1c64506de878c4f09a9d86d70 |
Division of Plastic and Reconstructive Surgery, University of Washington, Seattle, WA, United States; Division of Craniofacial and Plastic Surgery, Seattle Children's Hospital, Division of Plastic Surgery, Department of Surgery, University of São Paulo, São Paulo, Brazil; Department of Plastic, Reconstructive, and Aesthetic Surgery, Hacettepe University, Ankara, Turkey; Department of Surgery, Kwame Nkrumah University of Science and Technology, Kumasi, Ghana; Division of Plastic Reconstructive and Aesthetic Surgery, Department of Surgery, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Cleft and Craniofacial Center Dr. Cipto Mangunkusumo Hospital; and School of Medicine, Shanghai Jiao Tong University, Shanghai, China |
Massenburg, B.B., Division of Plastic and Reconstructive Surgery, University of Washington, Seattle, WA, United States; Hopper, R.A., Division of Plastic and Reconstructive Surgery, University of Washington, Seattle, WA, United States; Crowe, C.S., Division of Craniofacial and Plastic Surgery, Seattle Children's Hospital, Division of Plastic Surgery, Department of Surgery, University of São Paulo, São Paulo, Brazil; Morrison, S.D., Department of Plastic, Reconstructive, and Aesthetic Surgery, Hacettepe University, Ankara, Turkey; Alonso, N., Department of Plastic, Reconstructive, and Aesthetic Surgery, Hacettepe University, Ankara, Turkey; Calis, M., Department of Surgery, Kwame Nkrumah University of Science and Technology, Kumasi, Ghana; Donkor, P., Division of Plastic Reconstructive and Aesthetic Surgery, Department of Surgery, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Kreshanti, P., Cleft and Craniofacial Center Dr. Cipto Mangunkusumo Hospital; and School of Medicine, Shanghai Jiao Tong University, Shanghai, China; Yuan, J., Division of Plastic and Reconstructive Surgery, University of Washington, Seattle, WA, United States |
Background: Orofacial clefts are one of the most common congenital anomalies, but this disease burden is unevenly distributed worldwide. The authors hypothesize that this burden falls disproportionately on the countries with the smallest surgical workforce or lowest Socio-Demographic Index, rather than those with the highest prevalence of disease. Methods: The authors estimated the prevalence and disease burden of orofacial clefting from 1990 to 2017 in 195 countries using the Global Burden of Disease methodology. Prevalence and disability-adjusted life-years were compared geographically, temporally, and against the size of the national surgical workforce, Socio-Demographic Index, and income status. Linear and logarithmic regressions were performed. Results: In 2017, the prevalence of orofacial clefting was estimated to be 10.8 million people, representing a disease burden of 652,084 disability-adjusted life-years, with most of this disease burden experienced by low- and middle-income countries (94.1%). From 1990 to 2017, there was a decrease in disease burden (-70.2%) and prevalence (-4.9%). There was negative logarithmic association between surgical workforce size and disease burden, with a surgical workforce of greater than six providers per 100,000 population (3.6 disability-adjusted life-years versus 22.4 disability-adjusted life-years per 100,000 population; p < 0.0001). Conclusions: Burden of orofacial clefting has a strong negative association with the size of the surgical workforce, suggesting that strengthening the surgical workforce will help alleviate this burden. Epidemiologic data on countries and regions with inadequate surgical workforces and high disease burden should guide future research efforts and allocation of resources, and guide the treatment and educational goals of international charitable organizations. © 2021 Lippincott Williams and Wilkins. All rights reserved. |
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cleft lip; cleft palate; global disease burden; global health; health service; human; organization and management; prevalence; reconstructive surgery; Cleft Lip; Cleft Palate; Global Burden of Disease; Global Health; Health Services Needs and Demand; Health Workforce; Humans; Prevalence; Reconstructive Surgical Procedures |
Lippincott Williams and Wilkins |
00321052 |
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34550940 |
Article |
Q1 |
1841 |
1560 |
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704 |
Setiani R.U., Batubara E.A.D., Adiarto S., Siddiq T., Indriani S., Siahaan I.H. |
57277340700;57220786003;8603606800;57206239827;57213831064;57278163100; |
Successful Ovarian Vein Embolization of a Multiparous Woman with Pelvic Congestion Syndrome |
2021 |
International Journal of Angiology |
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https://www.scopus.com/inward/record.uri?eid=2-s2.0-85115934784&doi=10.1055%2fs-0041-1731272&partnerID=40&md5=3d3e2b558ea0c0ec2f0afad82a5a9503 |
Department of Cardiology and Vascular Medicine, National Cardiovascular Centre Harapan Kita, Faculty of Medicine, Universitas Indonesia, Jakarta, 11420, Indonesia; Department of Cardiology and Vascular Medicine, Persahabatan Public Hospital, Jakarta, Indonesia |
Setiani, R.U., Department of Cardiology and Vascular Medicine, National Cardiovascular Centre Harapan Kita, Faculty of Medicine, Universitas Indonesia, Jakarta, 11420, Indonesia; Batubara, E.A.D., Department of Cardiology and Vascular Medicine, National Cardiovascular Centre Harapan Kita, Faculty of Medicine, Universitas Indonesia, Jakarta, 11420, Indonesia; Adiarto, S., Department of Cardiology and Vascular Medicine, National Cardiovascular Centre Harapan Kita, Faculty of Medicine, Universitas Indonesia, Jakarta, 11420, Indonesia; Siddiq, T., Department of Cardiology and Vascular Medicine, National Cardiovascular Centre Harapan Kita, Faculty of Medicine, Universitas Indonesia, Jakarta, 11420, Indonesia; Indriani, S., Department of Cardiology and Vascular Medicine, National Cardiovascular Centre Harapan Kita, Faculty of Medicine, Universitas Indonesia, Jakarta, 11420, Indonesia; Siahaan, I.H., Department of Cardiology and Vascular Medicine, Persahabatan Public Hospital, Jakarta, Indonesia |
Pelvic congestion syndrome (PCS) is a clinical syndrome supported by specific findings, such as ovarian vein's dilatation, that cause pelvic vein congestion. Although many theories are explaining the pathophysiologies of this condition, the underlying cause remains unknown. The clinical manifestations of PCS are various including chronic pelvic pain (CPP), voiding disturbances, or ureteral obstruction. Imaging modality, such as ultrasonography, computed tomography (CT scan), magnetic resonance imaging (MRI), and venography, are needed to confirm and exclude the differential diagnosis. Currently, American venous forum guidelines recommended endovascular therapy which is percutaneous embolization as the first option therapy of PCS. Here, we reported a 35-year-old woman with PCS who underwent successful percutaneous embolization therapy. © 2021. International College of Angiology. All rights reserved. |
chronic pelvic pain; multiparous woman; pelvic congestion syndrome; percutaneous embolization; venography |
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Thieme Medical Publishers, Inc. |
10611711 |
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Article |
Q3 |
293 |
15070 |
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707 |
Aulia I., Mustika R., Menaldi S.L. |
57204495153;57220273147;57192918198; |
Impact of Women's Domination in Plastic Surgery Residency Program in Indonesia |
2021 |
Plastic and Reconstructive Surgery - Global Open |
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e3757 |
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https://www.scopus.com/inward/record.uri?eid=2-s2.0-85115629156&doi=10.1097%2fGOX.0000000000003757&partnerID=40&md5=de23c6b8c2c9f64536023cb3cf54a1f3 |
Division of Plastic Reconstructive and Aesthetic Surgery, Department of Surgery, Dr. Cipto Mangunkusumo Hospital, RSCM Gedung A, Jalan Diponegoro No. 71, DKI Jakarta, Jakarta Pusat, 10430, Indonesia; Department of Medical Education, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Cluster of Medical Education Center, Indonesian Medical Education and Research Institute (IMERI), Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Department of Dermatovenereology, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia |
Aulia, I., Division of Plastic Reconstructive and Aesthetic Surgery, Department of Surgery, Dr. Cipto Mangunkusumo Hospital, RSCM Gedung A, Jalan Diponegoro No. 71, DKI Jakarta, Jakarta Pusat, 10430, Indonesia, Department of Medical Education, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Mustika, R., Department of Medical Education, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia, Cluster of Medical Education Center, Indonesian Medical Education and Research Institute (IMERI), Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Menaldi, S.L., Department of Medical Education, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia, Department of Dermatovenereology, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia |
Background: A shift in gender dominance from man to woman in the medical field has occurred from time to time globally, including in Indonesia's plastic surgery community. This shift may alter the education and clinical settings of plastic surgery. This study aimed to explore the effect of the phenomenon of women's dominance in plastic surgery residency programs in Indonesia. Methods: This qualitative study was conducted using a phenomenological approach on three plastic surgery residency programs in Indonesia. Academic report review, focus group discussions, and in-depth interviews of residents, lecturers, residency program managers, and alumni user groups were selected using the maximum variation sampling method. Data obtained were analyzed and processed thematically. Results: Three themes emerged based on the educational process timeline: pre-education, intra-education, and post-education. Each timeline had several themes that mutually influenced the educational process. In the pre-educational process, residents' personal characters were affected by societies' positive and negative perceptions. The working environment, impact of women's dominance, and cultural dimension affected the intra-educational process. When entering the career life, residents expected an ideal working environment and had particular workplace preferences to achieve their well-being. Conclusions: The impact of women's dominance during the educational program affected residents' daily dynamics. However, this dominance did not affect the quality of education and workloads. © 2021 Lippincott Williams and Wilkins. All rights reserved. |
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Lippincott Williams and Wilkins |
21697574 |
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Article |
Q2 |
759 |
6437 |
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