No records
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188 |
Hamid A.R.A.H., Wangge G. |
57202054669;36497482500; |
The importance of evidence based education and policy in public health: Lessons learned from a repeated pandemic |
2021 |
Medical Journal of Indonesia |
30 |
3 |
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175 |
176 |
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https://www.scopus.com/inward/record.uri?eid=2-s2.0-85118807075&doi=10.13181%2fmji.ed.215821&partnerID=40&md5=9f5b4d7b96f6ec8842d115c438f55a1f |
Medical Journal of Indonesia, Universitas Indonesia, Jakarta, Indonesia; Department of Urology, Faculty of Medicine, Cipto Mangunkusumo Hospital, Universitas Indonesia, Jakarta, Indonesia; Southeast Asian Ministers of Education-Regional Centre for Food and Nutrition (SEAMEO RECFON)/Pusat Kajian Gizi Regional Universitas Indonesia (PKGR UI), Jakarta, Indonesia |
Hamid, A.R.A.H., Medical Journal of Indonesia, Universitas Indonesia, Jakarta, Indonesia, Department of Urology, Faculty of Medicine, Cipto Mangunkusumo Hospital, Universitas Indonesia, Jakarta, Indonesia; Wangge, G., Medical Journal of Indonesia, Universitas Indonesia, Jakarta, Indonesia, Southeast Asian Ministers of Education-Regional Centre for Food and Nutrition (SEAMEO RECFON)/Pusat Kajian Gizi Regional Universitas Indonesia (PKGR UI), Jakarta, Indonesia |
[No abstract available] |
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coronavirus disease 2019; disease transmission; early diagnosis; Editorial; evidence based medicine; health care policy; human; Indonesia; medical education; medical research; nonhuman; pandemic; polymerase chain reaction; public health; Spanish influenza; vaccination |
Faculty of Medicine, Universitas Indonesia |
08531773 |
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Editorial |
Q4 |
164 |
21905 |
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189 |
Louhenapessy N., Gantini R.S.E., Rahayu S., Lilipory E., Wibowo H., Soedarmono Y., Sutanto I. |
57328098200;57328652300;57189095014;57328098300;57217690943;35729808300;6603791639; |
Evaluating laboratory screening tests for malaria on blood donor candidates to reduce the risk of transfusion-transmitted malaria in an endemic area of indonesia |
2021 |
Medical Journal of Indonesia |
30 |
3 |
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191 |
197 |
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https://www.scopus.com/inward/record.uri?eid=2-s2.0-85118766270&doi=10.13181%2fmji.oa.215491&partnerID=40&md5=56dffb7462c5b89ab6601b6099db844e |
Biomedical Science Institute, Transfusion Science Program, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Central Blood Transfusion Services, Jakarta, Indonesia; Blood Bank Technology, Indonesian Red Cross, Jakarta, Indonesia; Integrated Laboratory Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Provincial Health Office of Ambon City, Maluku, Indonesia; Department of Parasitology, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Directorate General of Health Care, Ministry of Health, Jakarta, Indonesia |
Louhenapessy, N., Biomedical Science Institute, Transfusion Science Program, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Gantini, R.S.E., Biomedical Science Institute, Transfusion Science Program, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia, Central Blood Transfusion Services, Jakarta, Indonesia, Blood Bank Technology, Indonesian Red Cross, Jakarta, Indonesia; Rahayu, S., Integrated Laboratory Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Lilipory, E., Provincial Health Office of Ambon City, Maluku, Indonesia; Wibowo, H., Department of Parasitology, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Soedarmono, Y., Directorate General of Health Care, Ministry of Health, Jakarta, Indonesia; Sutanto, I., Department of Parasitology, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia |
BACKGROUND Laboratory screening of blood donors for malaria has not been routinely performed in Indonesia. Current policy and practice simply exclude donors based on a history of active clinical malaria. This study was aimed to evaluate laboratory screening tests for malaria among blood donors in an endemic area of Indonesia. METHODS The study was conducted on 550 consecutive blood samples withdrawn from volunteer donors at the Red Cross Blood Transfusion Unit in Ambon city using microscopic and rapid diagnostic tests for antigen as well as for antibody. Furthermore, 248 of those 550 samples were also tested for the presence of malaria DNA using 18S rRNA marker. Statistical analysis was done descriptively using SPSS software version 15 (SPSS Inc., USA). RESULTS The overall malaria positivity rate among the donors was 4.5% (25/550). None of the specimens tested using microscopy or rapid test for malaria antigen assay were positive. However 22 (4.0%) samples were positive for malaria antibody against Plasmodium falciparum, while 3 (1.2%) were positive by PCR. CONCLUSIONS Laboratory testing for blood donors may be used to prevent transfusion-transmitted malaria in an endemic area of Indonesia. © 2021, Faculty of Medicine, Universitas Indonesia. All rights reserved. |
Blood donors; Indonesia; Malaria |
hemoglobin; immunoglobulin A antibody; immunoglobulin G antibody; immunoglobulin M antibody; RNA 18S; adolescent; adult; Article; blood donor; blood transmission; body weight; endemic disease; female; Giemsa stain; human; Indonesia; laboratory test; major clinical study; malaria; male; microscopy; nonhuman; Plasmodium falciparum; Plasmodium malariae; Plasmodium vivax; polymerase chain reaction; risk reduction; screening test |
Faculty of Medicine, Universitas Indonesia |
08531773 |
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Article |
Q4 |
164 |
21905 |
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190 |
Nugroho C.M.H., Silaen O.S.M., Kurnia R.S., Soejoedono R.D., Poetri O.N., Soebandrio A. |
57219405299;57219408428;57209271620;26424105300;45461221800;8602893200; |
Isolation and molecular characterization of the hemagglutinin gene of H9N2 avian influenza viruses from poultry in Java, Indonesia |
2021 |
Journal of Advanced Veterinary and Animal Research |
8 |
3 |
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423 |
434 |
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https://www.scopus.com/inward/record.uri?eid=2-s2.0-85117949519&doi=10.5455%2fjavar.2021.h530&partnerID=40&md5=4af241f49519b916f0bed70def7d2751 |
Doctoral Program Biomedical Science, Faculty of Medicine, University of Indonesia, Jakarta, Indonesia; Animal Health Diagnostic Unit, PT Medika Satwa Laboratories, Bogor, Indonesia; Department of Animal Diseases and Public Health, Faculty of Veterinary Medicine, IPB University, Bogor, Indonesia; Eijkman Institute for Molecular Biology, Jakarta, Indonesia; Department of Microbiology, Faculty of Medicine, University of Indonesia, Jakarta, Indonesia |
Nugroho, C.M.H., Doctoral Program Biomedical Science, Faculty of Medicine, University of Indonesia, Jakarta, Indonesia; Silaen, O.S.M., Animal Health Diagnostic Unit, PT Medika Satwa Laboratories, Bogor, Indonesia; Kurnia, R.S., Doctoral Program Biomedical Science, Faculty of Medicine, University of Indonesia, Jakarta, Indonesia; Soejoedono, R.D., Department of Animal Diseases and Public Health, Faculty of Veterinary Medicine, IPB University, Bogor, Indonesia; Poetri, O.N., Department of Animal Diseases and Public Health, Faculty of Veterinary Medicine, IPB University, Bogor, Indonesia; Soebandrio, A., Eijkman Institute for Molecular Biology, Jakarta, Indonesia, Department of Microbiology, Faculty of Medicine, University of Indonesia, Jakarta, Indonesia |
Objective: The avian influenza virus (AIV) subtype H9N2 circulating in Indonesia has raised increasing concern about its impact on poultry and its public health risks. In this study, the H9N2 virus from chicken poultry farms in Java was isolated and characterized molecularly. Materials and Methods: Thirty-three pooled samples of chicken brain, cloacal swab, trachea, and oviduct were taken from multiple chickens infected with AIV in five regions of Java, Indonesia. The samples were isolated from specific pathogenic-free embryonated eggs that were 9 days old. Reverse transcription polymerase chain reaction and sequencing were used to identify H9N2 viruses. Results: This study was successful in detecting and characterizing 13 H9N2 isolates. The sequencing analysis of hemagglutinin genes revealed a 96.9%–98.8% similarity to the H9N2 AIV isolated from Vietnam in 2014 (A/muscovy duck/Vietnam/LBM719/2014). According to the phylogenetic analysis, all recent H9N2 viruses were members of the lineage Y280 and clade h9.4.2.5. Nine of the H9N2 isolates studied showed PSKSSR↓GLF motifs at the cleavage site, while four had PSKSSR↓GLF. Notably, all contemporary viruses have leucine (L) at position 216 in the receptor-binding region, indicating that the virus can interact with a human-like receptor. Conclusion: This study described the features of recent H9N2 viruses spreading in Java’s poultry industry. Additionally, H9N2 infection prevention and management must be implemented to avoid the occurrence of virus mutations in the Indonesian poultry industry. © 2021. The authors. Thisis an Open Access article distributed under the terms of the Creative Commons Attribution 4.0 License (http://creativecommons.org/licenses/by/4.0) |
Avian influenza; H9N2; HA gene; layer; phylogenetic analysis; sequencing |
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Network for the Veterinarians of Bangladesh |
23117710 |
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Article |
Q3 |
275 |
15692 |
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191 |
Wahdini S., Putra V.P., Sungkar S. |
57203684068;57299060700;57016857300; |
The prevalence of intestinal protozoan infections among children in southwest sumba based on the type of water sources |
2021 |
Infection and Chemotherapy |
53 |
3 |
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519 |
527 |
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https://www.scopus.com/inward/record.uri?eid=2-s2.0-85117295741&doi=10.3947%2fic.2021.0067&partnerID=40&md5=f72157a8065763eba10ce0eed22c987b |
Department of Parasitology, Faculty of Medicine Universitas Indonesia, Jakarta, Indonesia |
Wahdini, S., Department of Parasitology, Faculty of Medicine Universitas Indonesia, Jakarta, Indonesia; Putra, V.P., Department of Parasitology, Faculty of Medicine Universitas Indonesia, Jakarta, Indonesia; Sungkar, S., Department of Parasitology, Faculty of Medicine Universitas Indonesia, Jakarta, Indonesia |
Background: Intestinal protozoan infection is a public health problem in Indonesia, particularly in regions lacking clean water sources such as Perokonda and Perobatang villages, Southwest Sumba Regency, East Nusa Tenggara Province. The residents of Perokonda and Perobatang villages use wells and unprotected open springs respectively. Therefore, this study aims to determine the prevalence of intestinal protozoan infections in these two villages. Materials and Methods: This was a cross-sectional study, carried out in Perokonda and Perobatang from August 2016 to August 2017. A total of 291 children aged 6 months to 18 years were used as subjects. Furthermore, fecal examinations were carried out by preparing smears, which were stained with lugol solution and examined under the microscopes by four experienced technicians. The data were processed using SPSS version 20 and analyzed by chi-square test. Results: Among the 291 samples, the prevalence of intestinal protozoan infections was 20%, with 23.4% in Perokonda and 17.2% in Perobatang. The predominant species found were Blastocystis hominis (34.5%), Giardia lamblia (19.0%), and Entamoeba coli (15.5%). Moreover, approximately 69.0% of single infections were found while 31.0% were mixed and associated with 2 to 3 protozoan species. There were no significant differences between the prevalence of intestinal protozoan infections and the children in Perokonda and Perobatang villages (confidence interval 0.83 - 2.62, P = 0.19). Conclusion: The type of water sources has no relationship with the species of intestinal protozoan infecting children in Perokonda and Perobatang. © 2021 Korean Society for Antimicrobial Therapy. All rights reserved. |
Children 6 months to 18 years old; Intestinal protozoan; Southwest Sumba; Water sources |
adolescent; adult; Article; Blastocystis hominis; child; controlled study; cross-sectional study; Entamoeba coli; feces analysis; female; Giardia intestinalis; human; infant; intestine infection; major clinical study; male; pediatric patient; prevalence; protozoal infection; water supply |
Korean Society of Infectious Diseases, Korean Society for Antimicrobial Therapy, Korean Society for AIDS |
20932340 |
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Article |
Q2 |
724 |
6845 |
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192 |
Legiawati L., Raissa, Widaty S., Kekalih A., Dorthy I., Lubis F. |
57202804484;57240272100;57208261546;55633562200;57297917600;57239954700; |
Prevalence of hair disorders and their related factors among adolescent students in public boarding school, west java, indonesia |
2021 |
Pakistan Paediatric Journal |
45 |
3 |
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357 |
362 |
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https://www.scopus.com/inward/record.uri?eid=2-s2.0-85117179598&partnerID=40&md5=44d7f353baa4a714054391e217fb7893 |
Department of Dermatology and Venereology Aria Kekalih Department of Community Medicine Faculty of Medicine, Universitas Indonesia dr. Cipto Mangunkusumo National Central General Hospital, Central Jakarta, Indonesia |
Legiawati, L., Department of Dermatology and Venereology Aria Kekalih Department of Community Medicine Faculty of Medicine, Universitas Indonesia dr. Cipto Mangunkusumo National Central General Hospital, Central Jakarta, Indonesia; Raissa, Department of Dermatology and Venereology Aria Kekalih Department of Community Medicine Faculty of Medicine, Universitas Indonesia dr. Cipto Mangunkusumo National Central General Hospital, Central Jakarta, Indonesia; Widaty, S., Department of Dermatology and Venereology Aria Kekalih Department of Community Medicine Faculty of Medicine, Universitas Indonesia dr. Cipto Mangunkusumo National Central General Hospital, Central Jakarta, Indonesia; Kekalih, A., Department of Dermatology and Venereology Aria Kekalih Department of Community Medicine Faculty of Medicine, Universitas Indonesia dr. Cipto Mangunkusumo National Central General Hospital, Central Jakarta, Indonesia; Dorthy, I., Department of Dermatology and Venereology Aria Kekalih Department of Community Medicine Faculty of Medicine, Universitas Indonesia dr. Cipto Mangunkusumo National Central General Hospital, Central Jakarta, Indonesia; Lubis, F., Department of Dermatology and Venereology Aria Kekalih Department of Community Medicine Faculty of Medicine, Universitas Indonesia dr. Cipto Mangunkusumo National Central General Hospital, Central Jakarta, Indonesia |
Objective: Hair disorders in children and teenagers are abnormalities that often appear and can cause complex clinical problems. It can be congenital or acquired from the environment. The aim was to observe the prevalence of hair disorders and their related factors in specific population, also to recognize their dermoscopic description. Study Design: Descriptive cross-sectional study Place and Duration of Study: The research was conducted from September 2018 to February 2019 in one public boarding school (PBS), West Java. Material and Methods: Participants were 127 students consisting of 85 boys and 42 girls, with age ranging from 11-15 years. Diagnosis was determined by history taking, physical and dermoscopic examination. Results: The most common hair disorder was pediculosis capitis, identified in 86 students (67.7%). All girl subjects were diagnosed with it, while in boy group there were 44 out of 85 students. When the pediculosis capitis group was compared with no hair disease group, the statistically significant factors were gender, frequency of washing towel and habit of using towel. Other kind of hair disorders discovered were scarring alopecia (3.2%), seborrheic dermatitis (0.8%), and nevus sebaceous (0.8%). Conclusion: Very high prevalence of pediculosis capitis in this PBS is influenced by high occupancy in one bedroom, also poor hygiene, such as longer frequency of changing towel, and habit of sharing prayer dresses. These results should be an important note for public health officer to raise awareness about this case. © 2021, Pakistan Pediatric Journal. All rights reserved. |
Adolescent; Dermoscopy; Hair diseases; Lice infestations; Prevalence |
adolescent; alopecia; Article; awareness; body mass; child; cross-sectional study; epiluminescence microscopy; female; hair disease; hair loss; health care personnel; human; hygiene; Indonesia; major clinical study; male; pediculosis capitis; Pediculus humanus capitis; prevalence; scalp pruritus; school child; sebaceous nevus; seborrheic dermatitis; student |
Pakistan Pediatric Journal |
03044904 |
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Article |
Q4 |
122 |
26784 |
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193 |
Putrantyo I.I., Mosahebi A., Smith O., de Vega B. |
57268843400;55985666400;54881691700;57222467939; |
Investigating Effectiveness of Topical Autologous Platelet-rich Plasma as Prophylaxis to Prevent Wound Infection: A Systematic Review and Meta-analysis |
2021 |
Malaysian Journal of Medicine and Health Sciences |
17 |
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72 |
82 |
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https://www.scopus.com/inward/record.uri?eid=2-s2.0-85117073627&partnerID=40&md5=e2542cf5f0470226375c2d3b9af84e52 |
Division of Surgery and Interventional Science, University College London, Royal Free Hospital, London, NW3 2QG, United Kingdom; Faculty of Medicine Universitas Indonesia, Dr Cipto Mangunkusumo Hospital, Jakarta Pusat, 10430, Indonesia; Cell and Tissue Bank-Regenerative Medicine Center, Dr Soetomo General Hospital, Surabaya, 60286, Indonesia |
Putrantyo, I.I., Division of Surgery and Interventional Science, University College London, Royal Free Hospital, London, NW3 2QG, United Kingdom, Faculty of Medicine Universitas Indonesia, Dr Cipto Mangunkusumo Hospital, Jakarta Pusat, 10430, Indonesia; Mosahebi, A., Division of Surgery and Interventional Science, University College London, Royal Free Hospital, London, NW3 2QG, United Kingdom; Smith, O., Division of Surgery and Interventional Science, University College London, Royal Free Hospital, London, NW3 2QG, United Kingdom; de Vega, B., Division of Surgery and Interventional Science, University College London, Royal Free Hospital, London, NW3 2QG, United Kingdom, Cell and Tissue Bank-Regenerative Medicine Center, Dr Soetomo General Hospital, Surabaya, 60286, Indonesia |
Autologous platelet-rich plasma (PRP) was reported as having potent antimicrobial properties. However, the literature showed conflicting results. Therefore, we aim to investigate the effectiveness of topical autologous PRP as prophylaxis to prevent wound infection. We searched major electronic databases such as MEDLINE, EMBASE, CENTRAL, and Web of Science to identify RCT studies regarding this topic. The selection of included studies followed the PRISMA guidelines. We included ten RCTs comprising 1257 participants. In general, PRP showed no effect in reducing the risk of wound infection (RR: 0.84; 95% CI: 0.66–1.06; p=0.14). However, subgroup analysis based on wound characteristic showed that PRP significantly reduced wound infection risks in acute wounds (RR: 0.76; 95% CI: 0.58–0.99; p=0.04). Meanwhile, activation of PRP had no effect in reducing wound infection risks (p=0.77). In conclusion, we suggest routine autologous topical PRP application in acute wound care due to PRP antimicrobial properties and regenerative potential. © 2021 UPM Press. All rights reserved. |
Antimicrobial agent; Platelet-rich plasma; Systematic review; Topical administration; Wound infection |
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Universiti Putra Malaysia Press |
16758544 |
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Review |
Q4 |
144 |
23823 |
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194 |
Mansyur M. |
37085506800; |
Occupational health, productivity and evidence-based workplace health intervention |
2021 |
Acta Medica Philippina |
55 |
6 |
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602 |
603 |
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https://www.scopus.com/inward/record.uri?eid=2-s2.0-85116680924&doi=10.47895%2fAMP.V55I6.4273&partnerID=40&md5=e8cf11e83c91edd4e2dccb08e749b070 |
Department of Community Medicine, Faculty of Medicine, Universitas Indonesia |
Mansyur, M., Department of Community Medicine, Faculty of Medicine, Universitas Indonesia |
[No abstract available] |
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University of the Philippines Manila |
00016071 |
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Editorial |
Q4 |
128 |
25603 |
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195 |
Habiburrahman M., Lesmana E., Harmen F., Gratia N., Mirtha L.T. |
57320844200;57208440285;57288593800;57288763400;57193201450; |
The impact of sleep deprivation on work performance towards night-shift healthcare workers: An evidence-based case report |
2021 |
Acta Medica Philippina |
55 |
6 |
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650 |
664 |
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https://www.scopus.com/inward/record.uri?eid=2-s2.0-85116676334&doi=10.47895%2fAMP.V55I6.3157&partnerID=40&md5=279c9c6f812ba7d9e6cf09363847268d |
Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Department of Community Medicine, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Hospital of Universitas Indonesia, Depok, Indonesia |
Habiburrahman, M., Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Lesmana, E., Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Harmen, F., Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Gratia, N., Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Mirtha, L.T., Department of Community Medicine, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia, Hospital of Universitas Indonesia, Depok, Indonesia |
Background. Poor sleep and excessive fatigue among workers can reduce well-being and physical fitness. However, not many studies have mentioned how sleeping deprivation among night-shift healthcare workers impacted their work performance in multiple aspects. Method. We conducted an evidence-based case report (EBCR) of a night shift nurse who was worried about the impact of her sleep deprivation on her work performance in the future due to prior history of needle-stick injuries. We aimed to determine whether sleeping deprivation caused by regular night shifts leads to decreased work performance among night-shift healthcare workers by formulating a clinical question. Evidence was searched systematically using five major journal databases (Proquest, EBSCO-Host, PubMed, ScienceDirect, and Cochrane) and was assessed thoroughly using inclusion and exclusion criteria. Results. Eleven eligible studies were obtained with a medium level of evidence (III-IV), three systematic reviews with meta-analyses (SR-MA), three SR without MA, and five observational studies. All of them were analyzed and critically appraised using Oxford Evidence-Based Medicine and Joanna Briggs Institute tools. We found that reduced quantity and quality of sleep impacted all dimensions of work performance among healthcare professionals, be it in task performance (e.g., skill proficiency), contextual performance (e.g., communication skill and mental health issues), and patient and health worker safety (accident and medication error). It could also encourage counterproductive work behavior, such as absenteeism. Furthermore, sleep deprivation changes circadian rhythms, causing decreased information processing and affective recognition functions in some vital brain areas, ultimately affecting several work dimensions. Conclusion. In conclusion, stakeholders need to adjust proper shift scheduling for health care workers, practice sleep hygiene, maintain physical fitness, and consume nutritional food, positively correlated to health and productivity. © 2021 University of the Philippines Manila. All rights reserved. |
Evidence-based medicine; Healthcare worker; Night shift; Sleep deprivation; Work performance |
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University of the Philippines Manila |
00016071 |
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Article |
Q4 |
128 |
25603 |
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196 |
Alie I.R., Andriantoro H., Timan I.S., Sulistomo A.W., Illyas E.I., Mansyur M. |
57288933200;55037171500;6602793366;57024018500;57288423500;37085506800; |
Potency biomarker effect of endothelial microparticles (emps) for early prediction of cardiovascular risk in shift worker nurses |
2021 |
Acta Medica Philippina |
55 |
6 |
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616 |
620 |
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https://www.scopus.com/inward/record.uri?eid=2-s2.0-85116671512&doi=10.47895%2fAMP.V55I6.3142&partnerID=40&md5=10ceaf9c58aabc0ce93083d831644fe1 |
Program of Universitas Indonesia; Department of Cardiology and Vascular Faculty of Medicine, Universitas Indonesia; Department of Pathology Clinic, Faculty of Medicine, Universitas Indonesia; Department of Community Medicine, Faculty of Medicine, Universitas Indonesia; Department of Physiology, Faculty of Medicine, Universitas Indonesia |
Alie, I.R., Program of Universitas Indonesia; Andriantoro, H., Department of Cardiology and Vascular Faculty of Medicine, Universitas Indonesia; Timan, I.S., Department of Pathology Clinic, Faculty of Medicine, Universitas Indonesia; Sulistomo, A.W., Department of Community Medicine, Faculty of Medicine, Universitas Indonesia; Illyas, E.I., Department of Physiology, Faculty of Medicine, Universitas Indonesia; Mansyur, M., Department of Community Medicine, Faculty of Medicine, Universitas Indonesia |
Objectives. Shift work results in changing worker's behavior, food, and sleep patterns, which can cause circadian rhythm disturbance, which is a cardiovascular risk. Until now, a biomarker of early prediction of cardiovascular risk on shift workers is still not developed. This study aimed to assess the cardiovascular risk of shift worker nurses by detecting endothelial microparticles (EMPs). Methods. This longitudinal study compared six shift nurses and five non-shift nurses by measuring the EMPs using antigen CD31+ flow cytometry. All met the inclusion criteria consisting of 28 blood samples followed in one week shift. Results. EMPs among non-shift nurses were below 200 μL. However, shift nurses' EMPs increased above 200 μL with Man-Whitney U p = 0.000 on days 4 and 7 following a one shift per week schedule. Conclusion. There was an increase in shift workers' endothelial microparticles (EMP) which was a sign of cardiovascular risk. © 2021 University of the Philippines Manila. All rights reserved. |
Cardiovascular risk; CD31+; Endothelial microparticles (EMPs); Nurse; Shift work |
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University of the Philippines Manila |
00016071 |
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Article |
Q4 |
128 |
25603 |
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198 |
Kartika R.W., Alwi I., Yunir E., Waspadji S., Suyatna F.D., Bardosono S., Immanuel S., Sungkar S., Rachmat J., Silalahi T., Reksodiputro M.H. |
57223447932;15055173800;36520254800;8678136400;56039633100;21933841000;57272979000;57016857300;6507225348;56275255400;35090488800; |
Efficacy of Combining Hyaluronic Acid and Platelet-Rich Fibrin in Diabetic Foot Ulcer |
2021 |
Jordan Journal of Biological Sciences |
14 |
3 |
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607 |
611 |
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1 |
https://www.scopus.com/inward/record.uri?eid=2-s2.0-85115791952&partnerID=40&md5=76c1dc1bbdde331f901d412f6b6a83ba |
Doctoral Program in Medical Science Faculty of Medicine Universitas Indonesia, Department of Thoracic, Cardiac and Vascular Surgery, Faculty of Medicine Krida Wacana Christian University, Indonesia; Department of Internal Medicine, Faculty of Medicine Universitas Indonesia – Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Department of Clinical Pharmacology, Faculty of Medicine Universitas Indonesia, Indonesia; Department of Clinical Nutrition, Faculty of Medicine Universitas Indonesia, Jakarta, Indonesia; Department of Clinical Pathology, Faculty of Medicine Universitas Indonesia – Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Department of Parasitology, Faculty of Medicine Universitas Indonesia, Jakarta, Indonesia; Department of Thoracic Cardiac and Vascular Surgery, Faculty of Medicine Universitas Indonesia, Jakarta, Indonesia; Department of Internal Medicine, Faculty of Medicine Krida Wacana Christian University, Jakarta, Indonesia; Department of Otorhinolaryngology, Facial Plastic Reconstructive Division, Faculty of Medicine, Universitas Indonesia, Cipto Mangunkusumo Hospital, Jakarta, Indonesia |
Kartika, R.W., Doctoral Program in Medical Science Faculty of Medicine Universitas Indonesia, Department of Thoracic, Cardiac and Vascular Surgery, Faculty of Medicine Krida Wacana Christian University, Indonesia; Alwi, I., Department of Internal Medicine, Faculty of Medicine Universitas Indonesia – Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Yunir, E., Department of Internal Medicine, Faculty of Medicine Universitas Indonesia – Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Waspadji, S., Department of Internal Medicine, Faculty of Medicine Universitas Indonesia – Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Suyatna, F.D., Department of Clinical Pharmacology, Faculty of Medicine Universitas Indonesia, Indonesia; Bardosono, S., Department of Clinical Nutrition, Faculty of Medicine Universitas Indonesia, Jakarta, Indonesia; Immanuel, S., Department of Clinical Pathology, Faculty of Medicine Universitas Indonesia – Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Sungkar, S., Department of Parasitology, Faculty of Medicine Universitas Indonesia, Jakarta, Indonesia; Rachmat, J., Department of Thoracic Cardiac and Vascular Surgery, Faculty of Medicine Universitas Indonesia, Jakarta, Indonesia; Silalahi, T., Department of Internal Medicine, Faculty of Medicine Krida Wacana Christian University, Jakarta, Indonesia; Reksodiputro, M.H., Department of Otorhinolaryngology, Facial Plastic Reconstructive Division, Faculty of Medicine, Universitas Indonesia, Cipto Mangunkusumo Hospital, Jakarta, Indonesia |
Objectives: A chronic complication of type-2 diabetes mellitus (DMT-2) is Diabetic Foot Ulcer (DFU). The main treatment used in DFU is wound cleansing, followed by dressing the wound as a local control to increase tissue granulation and epithelialization. This study aims to compare the efficacy of the combination of Hyaluronic Acid with Platelet Rich Fibrin (HAPRF) and Platelet Rich Fibrin alone in DFU. Methods: We conducted a randomized controlled trial from July 2019 to April 2020. The study was approved by the Ethics Committee of the Faculty of Medicine of Universitas Indonesia ID 0855 / UN2.F1 / ETIK / 2018. Informed consent was obtained from the patients. This was a randomized clinical study to compare the efficacy of HAPRF and PRF in DFU one week post debridement. Twenty DFU samples were collected divided into 2 treatment groups: topical treatment using HAPRF compare with PRF alone. Assessment for wounds improvement was recorded using a digital camera 48 mega pixel with an accuracy of 0.1% on day-0, 3, 7, and 14. The results of the wound photographs were processed using ImageJ software. The granulation area (GA) and wound area (WA) were evaluated by IBM SPSS software v.20. The general data description was presented in median (range) value and parameter’s differences were conducted using Mann–Whitney test Results: The two treatment groups showed insignificant difference in characteristics between both group before intervention. The mean granulation width after two weeks of use HAPRF was 97.4% and PRF was 81.9%. Statistical analysis using Mann Whitney test showed granulation area of HAPRF group was significantly different compared with PRF group on day-3(p=0.047), day-7 ( p = 0.004) and day-14 ( p < 0.001). At the end of the wound healing process, the HAPRF group was significantly different compared with PRF group on Δ day 0−3 ( p=0.048), Δ day 0−7 ( p = 0.039), and Δ day 0−14 ( p = 0.023). Conclusions: HAPRF improves wound healing rate through increasing granulation tissue and epithelialization compared with PRF only in diabetic foot ulcer after 2 weeks post debridement compared to PRF. © 2021, Jordan Journal of Biological Sciences. All Rights Reserved. |
Delta Wound Area; Diabetic ulcer; Granulation Area; Hyaluronic Acid; Platelet Rich Fibrin |
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Hashemite University |
19956673 |
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Article |
Q3 |
216 |
18398 |
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