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141 |
Findyartini A., Raharjanti N.W., Greviana N., Prajogi G.B., Setyorini D. |
56543777300;57226872499;57197709749;57221911632;57218906783; |
Development of an app-based e-portfolio in postgraduate medical education using entrustable professional activities (Epa) framework: Challenges in a resource-limited setting |
2021 |
Asia Pacific Scholar |
6 |
4 |
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92 |
106 |
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https://www.scopus.com/inward/record.uri?eid=2-s2.0-85119047428&doi=10.29060%2fTAPS.2021-6-4%2fOA2459&partnerID=40&md5=6cdd410ca553690d4851ccd981856007 |
Department of Medical Education, Faculty of Medicine, Universitas Indonesia, Indonesia; Medical Education Center, Indonesian Medical Education and Research Institute (IMERI), Faculty of Medicine, Universitas Indonesia, Indonesia; Department of Psychiatry, Faculty of Medicine, Universitas Indonesia, Indonesia; Department of Oncology Radiation, Faculty of Medicine, Universitas Indonesia, Indonesia |
Findyartini, A., Department of Medical Education, Faculty of Medicine, Universitas Indonesia, Indonesia, Medical Education Center, Indonesian Medical Education and Research Institute (IMERI), Faculty of Medicine, Universitas Indonesia, Indonesia; Raharjanti, N.W., Department of Psychiatry, Faculty of Medicine, Universitas Indonesia, Indonesia; Greviana, N., Department of Medical Education, Faculty of Medicine, Universitas Indonesia, Indonesia, Medical Education Center, Indonesian Medical Education and Research Institute (IMERI), Faculty of Medicine, Universitas Indonesia, Indonesia; Prajogi, G.B., Department of Oncology Radiation, Faculty of Medicine, Universitas Indonesia, Indonesia; Setyorini, D., Medical Education Center, Indonesian Medical Education and Research Institute (IMERI), Faculty of Medicine, Universitas Indonesia, Indonesia |
Introduction: E-portfolio may facilitate the entrustment process from supervisors to residents in postgraduate medical education. The present study was aimed at identifying necessary features of an e-portfolio application and to conduct pilot study in a teaching hospital. Methods: Six programs participated. Eight interviews with education directors and six focus group discussions with residents and supervisors were completed for the needs analysis stage. The application was developed based on the thematic analysis of the needs analysis stage. The mobile-app e-portfolio pilot was conducted for four weeks and a modified version of the System Usability Scale (SUS) was distributed to participants following the pilot program. Results: Key features of the e-portfolio were identified. A total of 45 supervisors and 66 residents participated in the pilot study. The residents utilised the application according to the clinical activities and supervision level, and the information was fed to the supervisors as per the application design. Challenges during the pilot study in terms of feedback provision and residents’ workload which influence the e-portfolio use for entrustment decisions are discussed. Conclusion: Current e-portfolio features were created for supervision and are potential to facilitate the entrustment process in Entrustable Professional Activities (EPA) implementation. The pilot study highlighted challenges of the implementation which should be considered for future improvement. © 2021 TAPS. All rights reserved. |
E-Portfolio; Entrustable Professional Activities; Needs Analysis; Pilot Study; Postgraduate Medical Education; Supervision |
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National University of Singapore, Faculty of Law |
24249335 |
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Article |
#N/A |
#N/A |
#N/A |
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142 |
Teja Y., Nareswari I. |
57325017200;57194336586; |
Acupuncture Therapies for Addressing Post Odontectomy Neuropathy |
2021 |
Medical Acupuncture |
33 |
5 |
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358 |
363 |
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https://www.scopus.com/inward/record.uri?eid=2-s2.0-85118590707&doi=10.1089%2facu.2020.1472&partnerID=40&md5=28463ebc7dc0a38e9601eb0cf906c286 |
Department of Medical Acupuncture, RSUPN Dr. Cipto Mangunkusumo, Central Jakarta, DKI Jakarta, Indonesia; Medical Acupuncture Specialist Program, Faculty of Medicine, Universitas Indonesia, Daerah Istimewa Jakarta, Jakarta, Indonesia |
Teja, Y., Department of Medical Acupuncture, RSUPN Dr. Cipto Mangunkusumo, Central Jakarta, DKI Jakarta, Indonesia, Medical Acupuncture Specialist Program, Faculty of Medicine, Universitas Indonesia, Daerah Istimewa Jakarta, Jakarta, Indonesia; Nareswari, I., Department of Medical Acupuncture, RSUPN Dr. Cipto Mangunkusumo, Central Jakarta, DKI Jakarta, Indonesia, Medical Acupuncture Specialist Program, Faculty of Medicine, Universitas Indonesia, Daerah Istimewa Jakarta, Jakarta, Indonesia |
Background: Third-molar extraction is a common oral surgical procedure that can cause complications. Although rare, nerve injuries that result in permanent neuropathy can occur and include a variety of complaints such as sensory disorders, taste-sensation disorders, speech articulation disorders, etc. Acupuncture is one of several nonpharmacologic therapies that has played a role in managing neuropathic lesions and has been proven to produce good results. Case: A 44-year-old woman with postodontectomy neuropathy developed paresthesia, dysarthria, xerostomia, dysgeusia, pain in the gums and lower right jaw, a chewing disorder, and cephalgia. Her numerical rating scale (NRS) results were: lower right gum pain, 3/10; numbness of the tongue, 4/10; and headache, 1/10. A physical examination revealed dysarthria, a decreased sense of sharpness and dullness in the right mandibular nerve branches, decreased right masseter muscle contractions, and tenderness on the right GB 20 point. Electromyography revealed partial functional lesions in the postganglion at the right fifth cranial nerve. She had body acupuncture therapy at GV 20, GB 20, ST 5, ST 6, ST 7, CV 23, LI 4, HT 5, ST 36, LU 7, and KI 6; ear acupuncture at the Parotid and Shenmen points; and treatment with the Tan Balance Method. Results: After 3 consecutive sessions of acupuncture therapy, this patient's symptoms were reduced. Conclusions: Acupuncture was helpful for reducing paresthesia, dysarthria, xerostomia, dysgeusia, gum and lower right jaw pain, a chewing disorder, and cephalgia in this patient with postodontectomy neuropathy. Clinical trials are needed to support the findings in this case. © Copyright 2021, Mary Ann Liebert, Inc., publishers 2021. |
acupuncture; dysarthria; dysgeusia; neuropathy; odontectomy; paresthesia |
paracetamol; acupuncture; adult; analgesia; Article; baihui acupoint; case report; clinical article; daying acupoint; dysarthria; dysgeusia; electromyography; female; fengchi acupoint; gingiva pain; hegu acupoint; human; hypesthesia; jaw pain; jiache acupoint; lianquan acupoint; lieque acupoint; mandibular nerve; masseter muscle; mastication; muscle contraction; neuropathy; numeric rating scale; paresthesia; parotid gland; physical examination; postoperative complication; tongli acupoint; tongue; tooth extraction; trigeminal nerve; xerostomia; xiaguan acupoint; zhaohai acupoint; zusanli acupoint |
Mary Ann Liebert Inc. |
19336586 |
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Article |
Q2 |
281 |
15498 |
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144 |
Susiloretni K.A., Smith E.R., Suparmi, Marsum, Agustina R., Shankar A.H. |
55920057100;55479658700;57201388096;57203690495;57214141404;7005442634; |
The psychological distress of parents is associated with reduced linear growth of children: Evidence from a nationwide population survey |
2021 |
PLoS ONE |
16 |
10 October |
e0246725 |
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https://www.scopus.com/inward/record.uri?eid=2-s2.0-85118229642&doi=10.1371%2fjournal.pone.0246725&partnerID=40&md5=e63e172d790e5a4d43ab7ba273dd42d6 |
Semarang Health Polytechnic Ministry of Health - Poltekkes Kemenkes Semarang, Central Java, Semarang, Indonesia; Department of Global Health, George Washington University, Washington, D.C., United States; National Health Institute Research and Development, Jakarta, Indonesia; Faculty of Medicine, Department of Nutrition, Universitas Indonesia – Dr. Cipto Mangunkusumo General Hospital, Jakarta, Indonesia; Faculty of Medicine, Human Nutrition Research Center, Indonesian Medical Education and Research Institute, Universitas Indonesia, Jakarta, Indonesia; Eijkman-Oxford Clinical Research Unit, Eijkman Institute for Molecular Biology, Jakarta, Indonesia; Nuffield Department of Medicine, The Centre for Tropical Medicine and Global Health, University of Oxford, Oxford, United Kingdom |
Susiloretni, K.A., Semarang Health Polytechnic Ministry of Health - Poltekkes Kemenkes Semarang, Central Java, Semarang, Indonesia; Smith, E.R., Department of Global Health, George Washington University, Washington, D.C., United States; Suparmi, National Health Institute Research and Development, Jakarta, Indonesia; Marsum, Semarang Health Polytechnic Ministry of Health - Poltekkes Kemenkes Semarang, Central Java, Semarang, Indonesia; Agustina, R., Faculty of Medicine, Department of Nutrition, Universitas Indonesia – Dr. Cipto Mangunkusumo General Hospital, Jakarta, Indonesia, Faculty of Medicine, Human Nutrition Research Center, Indonesian Medical Education and Research Institute, Universitas Indonesia, Jakarta, Indonesia; Shankar, A.H., Eijkman-Oxford Clinical Research Unit, Eijkman Institute for Molecular Biology, Jakarta, Indonesia, Nuffield Department of Medicine, The Centre for Tropical Medicine and Global Health, University of Oxford, Oxford, United Kingdom |
Background Stunting, an indicator of restricted linear growth, has become a primary measure of childhood undernutrition due to its persistent high prevalence globally, and importance for health and development. Although the etiology is recognized as complex, most analyses have focused on social and biomedical determinants, with limited attention on psychological factors affecting care and nurturing in the home. We assessed whether the psychological distress of parents is related to child linear growth and stunting, and documented the associated risk factors, and examined the relationship between parental distress and behavioral and other risk factors for stunting. Methods We used data from the Indonesia National Health Survey 2013, including 46,315 children 6–59 months of age. Multivariate linear, logistic, and multilevel multinomial logistic regression, using survey weights, were used to assess the relationship between parental distress, as assessed by the WHO Self Reporting Questionnaire (SRQ20), with height-for-age z score (HAZ), stunting, and behavioral and other risk factors for stunting. Results Maternal, paternal and parental distress (i.e. both maternal and paternal distress) were associated with reduced linear growth of the children by 0.086 (95% CI -0.17, -0.00), 0.11 (95% CI -0.24, -0.02) and 0.19 (95% CI -0.37, -0.00) HAZ-scores, respectively. Maternal and paternal distress increased the risk of mild stunting (HAZ <-1) by 33% (95% CI 1.17,1.50) and 37% (95% CI 1.18,1.60), and the risk of moderate stunting (HAZ <-2) by 25% (95% CI 1.10,1.43) and 28% (95% CI 1.08,1.51]), respectively. Parental stress increased the risk of moderate stunting by 40% (95% CI 1.06,1.85). Amongst specific groups of risk factors, the proportion of HAZ-score lost was associated with socioeconomic factors (30.3%) including, low wealth, low maternal occupational status, low maternal education, rural residence, and low paternal occupational status; physiological factors (15.5%) including low maternal height, low maternal mid-upper arm circumference, being male, low paternal height; behavioral factors (8.9%) including open garbage disposal, paternal smoking, not using iodized salt; and experiencing at least one infectious diseases episode (1.1%). Conclusions Maternal, paternal and parental stress were associated with reduced linear growth of children. These findings highlight the complex etiology of stunting and suggest nutritional and other biomedical interventions are insufficient, and that promotion of mental and behavioral health programs for parents must be pursued as part of a comprehensive strategy to enhance child growth and development, i.e. improved caretaker capacity, integrated community development, improved parenting skills, as well as reduced gender discrimination, and domestic violence. © 2021 Susiloretni et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. |
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sodium chloride; adult; anthropometric parameters; arm circumference; Article; body height; child; child development; child growth; child parent relation; distress syndrome; domestic violence; education; female; health behavior; health program; health survey; height for age z score; human; Indonesia; infant; infection; male; maternal stress; multivariate logistic regression analysis; occupation; parental stress; paternal smoking; paternal stress; physiology; population; risk factor; rural area; Self Reporting Questionnaire 20; sex ratio; sexism; socioeconomics; stunting; waste disposal; wealth distribution; cross-sectional study; distress syndrome; educational status; growth disorder; nutritional status; physiology; preschool child; prevalence; psychology; rural population; Body Height; Ch |
Public Library of Science |
19326203 |
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34699530 |
Article |
Q1 |
990 |
4434 |
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145 |
Hansur L., Pawitan J.A. |
57296411600;6508348067; |
The potential of hydroxysafflor yellow a as an adjuvant in covid-19 patients with acute respiratory distress syndrome |
2021 |
International Medical Journal |
28 |
5 |
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527 |
531 |
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https://www.scopus.com/inward/record.uri?eid=2-s2.0-85117118067&partnerID=40&md5=caa56a92d25ef57cc5e5c3533887adf1 |
Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Faculty of Medicine, Universitas Muhammadiyah Makassar, Makassar, Indonesia; Department of Histology, Faculty of Medicine, Universitas Indonesia, Indonesia; Stem Cell Medical Technology Integrated Service Unit, Dr. Cipto Mangunkusumo General Hospital/ Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Stem Cell and Tissue Engineering Research Center, Indonesia Medical Education and Research Institute (IMERI), Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia |
Hansur, L., Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia, Faculty of Medicine, Universitas Muhammadiyah Makassar, Makassar, Indonesia; Pawitan, J.A., Department of Histology, Faculty of Medicine, Universitas Indonesia, Indonesia, Stem Cell Medical Technology Integrated Service Unit, Dr. Cipto Mangunkusumo General Hospital/ Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia, Stem Cell and Tissue Engineering Research Center, Indonesia Medical Education and Research Institute (IMERI), Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia |
Objective: To discuss the potential and molecular mechanism of Carthamus tincorius derived hydroxysafflor yellow A (HSYA) as an alternative herbal adjuvant that may regulate various signaling pathways that might be related to the regulatory effects in COVID-19 patients with ALI and ARDS. Methods: We search Web of Science, PubMed, and Scopus using keywords: Carthamus tinctorius, adjuvant, cytokine storm, COVID-19, SARS-Cov-2, acute lung injury (ALI), and Acute Respiratory Distress Syndrome (ARDS), on 11 September 2020, and 18 December 2020. Results and Discussions: In COVID-19 patients, SARS-CoV-2 replication might be associated with hyper induction of pro-in-flammatory cytokine, which is known as a cytokine storm, and may cause acute lung injury (ALI) that leads to Acute Respiratory Distress Syndrome (ARDS). Carthamus tincorius derived HSYA were used in many studies, in vivo in animal models or in vitro in cell lines and showed inhibition of multiple inflammatory pathways that were involved in ALI and ARDS, which might occur in covid-19 patients. HSYA showed pleiotropic effects in regulating cytokine levels. It regulated TNF-α, IL-1β, IL-6, IFN-β, and showed protective effect by blocking TLR4, MyD88, TRIF, IRF3, NF-κB to avoid cytokine storm and prevent tissue damage. HSYA was showed to reduce oxidative stress-mediated damage, and down-regulate inflammatory cytokines. Further, it was relatively safe when studied as an adjuvant in HIV and cancer patients. Conclusion: We supposed that HSYA could be used as an alternative adjuvant in COVID-19 patients with ARDS. However, clinical trials are needed to prove its efficacy in COVID-19 patients with ARDS. © 2021 Japan University of Health Sciences & Japan International Cultural Exchange Foundation. |
Carthamus tinctorius; COVID-19; Cytokine storm; HSYA; SARS-Cov-2 |
adjuvant; curcumin; hydroxysafflor yellow a; interleukin 1beta; interleukin 6; interleukin 8; myeloid differentiation factor 88; natural product; pathogen associated molecular pattern; toll like receptor 4; tumor necrosis factor; unclassified drug; acute lung injury; adult respiratory distress syndrome; antiinflammatory activity; apoptosis; Article; binding affinity; brain ischemia; cancer patient; coronavirus disease 2019; cytokine production; cytokine storm; down regulation; dyspnea; endothelial dysfunction; endothelium cell; enzyme activity; human; Human immunodeficiency virus; immune response; inflammation; lung edema; nonhuman; pleiotropy; protein expression; protein function; reperfusion injury; respiratory failure; Severe acute respiratory syndrome coronavirus 2; signal transduction |
Japan International Cultural Exchange Foundation |
13412051 |
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Article |
Q4 |
183 |
20490 |
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146 |
Dwijayanti A., Pawitan J.A. |
55743787900;6508348067; |
Mesenchymal stem cell aging, their environment and methods to restore their quality |
2021 |
International Medical Journal |
28 |
5 |
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520 |
523 |
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https://www.scopus.com/inward/record.uri?eid=2-s2.0-85117117062&partnerID=40&md5=e4cc00f4efb942f9321160eff1b790a8 |
Doctoral Program in Biomedical Sciences, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Department of Medical Pharmacy, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Department of Histology, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Stem Cell Medical Technology Integrated Service Unit, Cipto Mangunkusumo Central Hospital, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Stem Cell and Tissue Engineering Research Center, Indonesia Medical Education and Research Institute (IMERI), Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia |
Dwijayanti, A., Doctoral Program in Biomedical Sciences, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia, Department of Medical Pharmacy, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Pawitan, J.A., Department of Histology, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia, Stem Cell Medical Technology Integrated Service Unit, Cipto Mangunkusumo Central Hospital, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia, Stem Cell and Tissue Engineering Research Center, Indonesia Medical Education and Research Institute (IMERI), Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia |
Objective: This article aims to explore the aging of mesenchymal stem cells (MSCs) during cell expansion and available methods to restore their quality. Materials and methods: we searched articles in PubMed/Medline and our library to collect relevant publications of MSC aging, their microenvironment (niche), and various approaches to prevent MSC aging. Results and Discussion: MSC expansion during culture may cause cell aging, which is reflected by change in growth, geno-type, and phenotype that can be seen in morphology and function. There are various approaches that can be used to prevent MSC aging. Approaches to prevent MSC aging in culture can be done by various methods, including by determining donor characteristics, genetic engineering approaches, regulating stem cells microenvironment in vitro, and in vitro physical modification Conclusion: Prevention of MSC aging during culture can be done by selection of MSC sources, genetic modification, and microenvironment and physical adjustments. ©2021 Japan University of Health Sciences & Japan International Cultural Exchange Foundation. |
Aging; Cell culture; Mesenchymal stem cells; Micro environment; Propagation |
adult; article; cell aging; cell culture; DNA modification; genetic engineering; human; human cell; Medline; mesenchymal stem cell; microenvironment; phenotype; stem cell expansion |
Japan International Cultural Exchange Foundation |
13412051 |
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Article |
Q4 |
183 |
20490 |
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147 |
Merati T.P., Karyana M., Tjitra E., Kosasih H., Aman A.T., Alisjahbana B., Lokida D., Arlinda D., Maldarelli F., Neal A., Arif M., Gasem M.H., Lukman N., Sudarmono P., Lau C.-Y., Hadi U., Lisdawati V., Wulan W.N., Lane H.C., Siddiqui S. |
57203678680;24449083500;57204151009;6507043017;6701594071;6506944516;57190663838;57218444330;57210198407;57220466230;56740206600;6508371601;57190737414;6507855437;16245242000;55804160500;56786334300;57204491118;57197596240;8707129300; |
Prevalence of HIV infection and resistance mutations in patients hospitalized for febrile illness in Indonesia |
2021 |
American Journal of Tropical Medicine and Hygiene |
105 |
4 |
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960 |
965 |
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https://www.scopus.com/inward/record.uri?eid=2-s2.0-85117017901&doi=10.4269%2fajtmh.20-1595&partnerID=40&md5=f52639e32eebbadb71cd505b119b26d4 |
Faculty of Medicine, Universitas Udayana, Denpasar, Indonesia; National Institute of Health Research and Development, Ministry of Health, Republic of Indonesia, Jakarta, Indonesia; Indonesia Research Partnership on Infectious Disease (INA-RESPOND), Jakarta, Indonesia; Faculty of Medicine, Universitas Gadjah Mada, Yogyakarta, Indonesia; Faculty of Medicine, Universitas Padjadjaran, Bandung, Indonesia; Department of Clinical Pathology, Tangerang District Hospital, Tangerang, Indonesia; National Cancer Institute, National Institutes of Health, Bethesda, MD, United States; National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, United States; Faculty of Medicine, Universitas Hasanudin, Makassar, Indonesia; Faculty of Medicine, Universitas Diponegoro, Semarang, Indonesia; Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Faculty of Medicine, Universitas Airlangga, Surabaya, Indonesia; Sulianti Saroso, Infectious Disease Hospital, Jakarta, Indonesia; Indonesia Research Partnership on Infections Disease, Jalan Percetakan Negara No. 29, Jakarta, 10560, Indonesia |
Merati, T.P., Faculty of Medicine, Universitas Udayana, Denpasar, Indonesia; Karyana, M., National Institute of Health Research and Development, Ministry of Health, Republic of Indonesia, Jakarta, Indonesia, Indonesia Research Partnership on Infectious Disease (INA-RESPOND), Jakarta, Indonesia; Tjitra, E., National Institute of Health Research and Development, Ministry of Health, Republic of Indonesia, Jakarta, Indonesia; Kosasih, H., Indonesia Research Partnership on Infectious Disease (INA-RESPOND), Jakarta, Indonesia, Indonesia Research Partnership on Infections Disease, Jalan Percetakan Negara No. 29, Jakarta, 10560, Indonesia; Aman, A.T., Faculty of Medicine, Universitas Gadjah Mada, Yogyakarta, Indonesia; Alisjahbana, B., Faculty of Medicine, Universitas Padjadjaran, Bandung, Indonesia; Lokida, D., Department of Clinical Pathology, Tangerang District Hospital, Tangerang, Indonesia; Arlinda, D., National Institute of Health Research and Development, Ministry of Health, Republic of Indonesia, Jakarta, Indonesia, Indonesia Research Partnership on Infectious Disease (INA-RESPOND), Jakarta, Indonesia; Maldarelli, F., National Cancer Institute, National Institutes of Health, Bethesda, MD, United States; Neal, A., National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, United States; Arif, M., Faculty of Medicine, Universitas Hasanudin, Makassar, Indonesia; Gasem, M.H., Faculty of Medicine, Universitas Diponegoro, Semarang, Indonesia; Lukman, N., Indonesia Research Partnership on Infectious Disease (INA-RESPOND), Jakarta, Indonesia; Sudarmono, P., Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Lau, C.-Y., National Cancer Institute, National Institutes of Health, Bethesda, MD, United States; Hadi, U., Faculty of Medicine, Universitas Airlangga, Surabaya, Indonesia; Lisdawati, V., Sulianti Saroso, Infectious Disease Hospital, Jakarta, Indonesia; Wulan, W.N., Indonesia Research Partnership on Infectious Disease (INA-RESPOND), Jakarta, Indonesia; Lane, H.C., National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, United States; Siddiqui, S., National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, United States |
HIV prevalence in Indonesia is increasing, and only 64% of infected individuals know their status. In a prospective cohort of 1,453 hospitalized patients with unexplained fever, 46 (3.2%) had HIV, including 15 (1.1%) patients without a prior HIV diagnosis. Among 31 subjects previously known to have HIV, 21 (68%) had been receiving combination antiretroviral therapy (cART) at the time of enrollment. Of 39 HIV cases with HIV RNA levels $ 100 copies/mL, sequencing for genotype analysis and resistance testing was successful in 30 (77%) subjects. The most common HIV subtypes were AE (90%) and B (10%). Five (16.7%) subjects had resistance mutations to nucleoside and non-nucleoside reverse transcriptase inhibitors, and all of them were on cART. No evidence of transmitted drug resistance was found in newly diagnosed individuals. Hospital-based screening may be an efficient method to expand HIV testing and identify a significant number of new cases. Access to care, close monitoring, expansion of anti-retroviral options, and ensuring availability of CD4 determinations, viral load testing, and genotyping are crucial to control of the epidemic in Indonesia. © 2021 by The American Society of Tropical Medicine and Hygiene |
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nonnucleoside reverse transcriptase inhibitor; RNA directed DNA polymerase inhibitor; virus RNA; anti human immunodeficiency virus agent; adolescent; adult; aged; antiretroviral therapy; Article; child; cohort analysis; combination drug therapy; female; fever; genotype; hospital patient; hospitalization; human; Human immunodeficiency virus infection; Indonesia; major clinical study; male; nonhuman; prevalence; prospective study; virus mutation; virus resistance; antiviral resistance; drug effect; genetics; Human immunodeficiency virus 1; Human immunodeficiency virus infection; infant; middle aged; mutation; preschool child; very elderly; virology; young adult; Adolescent; Adult; Aged; Aged, 80 and over; Anti-HIV Agents; Child; Child, Preschool; Drug Resistance, Viral; Female; HIV Infection |
American Society of Tropical Medicine and Hygiene |
00029637 |
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34460416 |
Article |
Q1 |
1015 |
4298 |
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149 |
Mirza H., Rahmadi R. |
57208513330;57212589074; |
Peyronie disease: Our first experience with Ducket Baskin tunica albuginea plication (TAP) technique |
2021 |
International Journal of Surgery Case Reports |
87 |
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106451 |
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https://www.scopus.com/inward/record.uri?eid=2-s2.0-85116436763&doi=10.1016%2fj.ijscr.2021.106451&partnerID=40&md5=84094d95d09430b0098354a4215d5688 |
Division of Urology, Department of Surgery, Persahabatan Hospital, Indonesia; Department of Urology, Cipto Mangunkusumo Hospital, Faculty of Medicine Universitas Indonesia, Jakarta, Indonesia |
Mirza, H., Division of Urology, Department of Surgery, Persahabatan Hospital, Indonesia; Rahmadi, R., Department of Urology, Cipto Mangunkusumo Hospital, Faculty of Medicine Universitas Indonesia, Jakarta, Indonesia |
Introduction: Peyronie's Disease is a deformity of the penis. Surgical procedure options for Peyronie's disease treatment include grafting (curvature >60°) or plication (curvature <60°). This case report emphasizes the curvature degree and therapy options chosen, such as tunica albuginea plication instead of grafting. Case presentation: A 55-year-old male complains about a curved penis during erection. Examination shows penile bending 70° ventrally with ±15 cm length and 2x4cm size. The patient underwent Ducket-Baskin tunica albuginea placation (TAP). Postoperative unbent penis size decrement of ±3 cm, neither pain nor erectile dysfunction felt. Clinical discussion: Tunica plication is usually recommended in Peyronie's disease patients with curvature less than 60°, without an hourglass or hinge if grafting is not available. This technique is more simple, safe, the higher success rate of curvature correction (> 80%), low recurrency, low complication rate of penile hypoesthesia (approximately 10%), as well as low risk for postoperative erectile dysfunction. Conclusion: In our case, the tunica albuginea plication technique gives a good outcome in Peyronie's disease reconstruction. © 2021 The Authors |
Ducket-Baskin; Penile curvature; Penile deformity; Peyronie disease; Tunica albuginea plication |
adult; Article; case report; clinical article; conservative treatment; corpus cavernosum; diabetes mellitus; ducket baskin tunica albuginea placation; echography; erectile dysfunction; follow up; hospital admission; human; hypertension; male; male genital tract parameters; middle aged; pain; penis erection; penis length; Peyronie disease; physical examination; sexual intercourse; smoking; tunica albuginea; unbent penis size decrement |
Elsevier Ltd |
22102612 |
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Article |
Q3 |
232 |
17549 |
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151 |
Erwin U.S., Cahyadi S.D. |
57216822223;57270709000; |
Total elbow arthroplasty as a reconstruction option for distal humerus osteosarcoma: A case report |
2021 |
International Journal of Surgery Case Reports |
87 |
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106392 |
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https://www.scopus.com/inward/record.uri?eid=2-s2.0-85115606771&doi=10.1016%2fj.ijscr.2021.106392&partnerID=40&md5=0a0870e6be133daae5f326c3ac0989f8 |
Department of Orthopaedic and Traumatology, Faculty of Medicine Universitas Indonesia, Dr. Cipto Mangunkusumo Hospital, Indonesia; Department of Orthopaedic and Traumatology, Faculty of Medicine Universitas Indonesia, Persahabatan General Hospital, Indonesia |
Erwin, U.S., Department of Orthopaedic and Traumatology, Faculty of Medicine Universitas Indonesia, Dr. Cipto Mangunkusumo Hospital, Indonesia; Cahyadi, S.D., Department of Orthopaedic and Traumatology, Faculty of Medicine Universitas Indonesia, Persahabatan General Hospital, Indonesia |
Introduction: Osteosarcoma is the second most common malignant bone tumor. The humerus is the third most common anatomical location for osteosarcoma, however, osteosarcoma around the elbow joint is uncommon. The intricacy of the elbow joint, limited soft tissue coverage, and proximity to nerves and arteries make the surgical resection and reconstruction complicated. Case report: A 17-year-old boy came with a chief complaint of lump and pain on his left elbow. One month later, the patient felt there was a lump with a size of a marble on the left elbow, which getting bigger to a size of a tenis ball. Physical examination showed mass on the posterior aspect of the elbow with the size 14x12cm. Plain radiographs revealed osteolytic lesion and periosteal reaction of the distal humerus and the magnetic resonance imaging (MRI) showed a low intensity on T2-weighted imaging. Histopathological examination suggested osteosarcoma. The patient underwent neoadjuvant chemotherapy for 3 cycles. The patient was treated with limb salvage surgery by wide excision, cryosurgery followed by total elbow arthroplasty and ORIF with plate and screw. Postoperative plain radiographs showed the plate and screws are well-fixated. The patient can slowly regain his elbow motion without limitation one month postoperatively. Conclusions: Distal humerus in an unusual site for osteosarcoma. Total elbow arthroplasty and ORIF with plate and screw is a favorable reconstruction option for distal humerus osteosarcoma with excellent postoperative functional outcomes. © 2021 The Authors |
Distal humerus; Osteosarcoma; Total elbow arthroplasty |
cisplatin; doxorubicin; ifosfamide; liquid nitrogen; adolescent; arthralgia; Article; bone atrophy; bone radiography; case report; clinical article; computer assisted tomography; debridement; distal humerus; elbow arthroplasty; general anesthesia; histopathology; human; joint radiography; limb salvage; male; multiple cycle treatment; neoadjuvant chemotherapy; nuclear magnetic resonance imaging; osteosarcoma; osteotomy; periosteum; physical examination; postoperative care; radial artery; radial nerve; range of motion; reconstructive surgery; room temperature; total arthroplasty; ulnar nerve |
Elsevier Ltd |
22102612 |
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Article |
Q3 |
232 |
17549 |
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152 |
Oswari H., Alatas F.S., Hegar B., Cheng W., Pramadyani A., Benninga M.A., Rajindrajith S. |
12777323800;57217150164;6506273944;57204068621;57204063138;7003532912;23475357200; |
Aerophagia Study in Indonesia: Prevalence and Association with Family-related Stress |
2021 |
Journal of Clinical Gastroenterology |
55 |
9 |
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772 |
777 |
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https://www.scopus.com/inward/record.uri?eid=2-s2.0-85115434505&doi=10.1097%2fMCG.0000000000001434&partnerID=40&md5=6e63f2b47973c55f30df2a8a6c98489f |
Department of Child Health, Gastrohepatology Division, Faculty of Medicine, Cipto Mangunkusumo Hospital, Universitas Indonesia, Jakarta, Indonesia; Department of Paediatric Gastroenterology and Nutrition, Emma children'S, Hospital, Amsterdam University Medical Centre, Amsterdam, Netherlands; Department of Paediatrics, University of Colombo, Colombo, Sri Lanka |
Oswari, H., Department of Child Health, Gastrohepatology Division, Faculty of Medicine, Cipto Mangunkusumo Hospital, Universitas Indonesia, Jakarta, Indonesia; Alatas, F.S., Department of Child Health, Gastrohepatology Division, Faculty of Medicine, Cipto Mangunkusumo Hospital, Universitas Indonesia, Jakarta, Indonesia; Hegar, B., Department of Child Health, Gastrohepatology Division, Faculty of Medicine, Cipto Mangunkusumo Hospital, Universitas Indonesia, Jakarta, Indonesia; Cheng, W., Department of Child Health, Gastrohepatology Division, Faculty of Medicine, Cipto Mangunkusumo Hospital, Universitas Indonesia, Jakarta, Indonesia; Pramadyani, A., Department of Child Health, Gastrohepatology Division, Faculty of Medicine, Cipto Mangunkusumo Hospital, Universitas Indonesia, Jakarta, Indonesia; Benninga, M.A., Department of Paediatric Gastroenterology and Nutrition, Emma children'S, Hospital, Amsterdam University Medical Centre, Amsterdam, Netherlands; Rajindrajith, S., Department of Paediatrics, University of Colombo, Colombo, Sri Lanka |
Background: Aerophagia is a functional gastrointestinal disorder characterized by repeated air swallowing leading to chronic abdominal distension. Symptoms can be long lasting, lead to frustration, and distress. This study describes prevalence, related factors, and symptomatology of aerophagia, together with its relationship with emotional stress. Materials and Methods: Cross-sectional study. Adolescents aged 10 to 17 years from selected state schools by convenient sampling from Jakarta, Indonesia, were recruited. Rome III self-administered questionnaire was used to compile data on gastrointestinal symptoms. Data on sociodemographic characteristics, intestinal and extraintestinal symptoms, and stressful life events were collected using a separate questionnaire. Results: A total of 1796 questionnaires were included in the analysis [males 732 (40.8%), mean age 13.58 (SD 0.992) years]. There were 81 (4.5%) subjects diagnosed with aerophagia. When the criterion of belching was removed from the diagnosis of aerophagia, the prevalence drops to only 2 (0.1%). subjects. Bivariate analysis showed that sociodemographic factors have no correlation with aerophagia. In subjects with aerophagia, among the intestinal-related and extraintestinal symptoms, only loss of appetite was significantly more common in the aerophagia population (33.3%) when compared with controls (22.8%). Death of a close family member [adjusted odds ratio (OR), 2.78; 95% confidence interval (CI), 1.46-5.31; P=0.002], divorce or separation of parents (adjusted OR, 2.54; 95% CI, 1.38-4.66; P=0.003), and divorce followed by separate individual remarriage of parents (adjusted OR, 2.01; 95% CI, 1.01-3.98; P=0.046) were found to be significantly associated with aerophagia by multivariate analysis. Conclusions: The prevalence of aerophagia was found in 4.5% of Indonesian school-aged children according to Rome III criteria, but the prevalence was found only 0.1% if the belching is removed from the criteria. Besides the main symptoms, only loss of appetite was significantly more common in aerophagia among intestinal-related and extraintestinal symptoms. Family-related stress showed a significant correlation with aerophagia. © 2021 Lippincott Williams and Wilkins. All rights reserved. |
adolescent; aerophagia; emotional stress; loss of appetite |
abdominal distension; abdominal pain; adolescent; aerophagia; air; Article; bivariate analysis; child; clinical feature; constipation; controlled study; cross-sectional study; death; demography; divorce; dizziness; emotional stress; eructation; family; family stress; female; fever; flatulence; gastrointestinal symptom; headache; human; Indonesia; life event; limb pain; loss of appetite; major clinical study; male; nausea; photophobia; prevalence; questionnaire; sampling; school; sensitivity analysis; separated parent; swallowing; vomiting; anxiety; Indonesia; Adolescent; Aerophagy; Anxiety; Child; Cross-Sectional Studies; Humans; Indonesia; Male; Prevalence; Surveys and Questionnaires |
Lippincott Williams and Wilkins |
01920790 |
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33009193 |
Article |
Q2 |
1141 |
3580 |
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153 |
Wahyudi M., Satria O., Prawirodihardjo B., Zulhandani M. |
57053464800;57196472120;57212305700;57265047500; |
Periosteal ostoesarcoma of the femur treated with modified capanna procedure: A case report |
2021 |
International Journal of Surgery Case Reports |
87 |
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106414 |
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https://www.scopus.com/inward/record.uri?eid=2-s2.0-85115265650&doi=10.1016%2fj.ijscr.2021.106414&partnerID=40&md5=f8bb94e201a4ad8fb7d73fc479c1b541 |
Orthopaedic Oncology Consultant, Department of Orthopaedic and Traumatology, Fatmawati General Hospital Jakarta, Indonesia; Hand and Microsurgery Consultant, Department of Orthopaedic and Traumatology, Fatmawati General Hospital Jakarta, Indonesia; Anatomic Pathologist, Department of Anatomical Pathology, Fatmawati General Hospital Jakarta, Indonesia; Orthopaedic and Traumatology Resident, Faculty of Medicine Universitas Indonesia, Dr. Cipto Mangunkusumo General Hospital, Jakarta, Indonesia |
Wahyudi, M., Orthopaedic Oncology Consultant, Department of Orthopaedic and Traumatology, Fatmawati General Hospital Jakarta, Indonesia; Satria, O., Hand and Microsurgery Consultant, Department of Orthopaedic and Traumatology, Fatmawati General Hospital Jakarta, Indonesia; Prawirodihardjo, B., Anatomic Pathologist, Department of Anatomical Pathology, Fatmawati General Hospital Jakarta, Indonesia; Zulhandani, M., Orthopaedic and Traumatology Resident, Faculty of Medicine Universitas Indonesia, Dr. Cipto Mangunkusumo General Hospital, Jakarta, Indonesia |
Introduction: Periosteal osteosarcoma is a rare type of primary bone tumor. A vascularized fibula graft incorporates this revolutionary approach with a traditional massive allograft to reconstruct large femur and tibia defects during oncological resection. A structurally competent reconstruction with improved vascular and osteogenic capacities with the ability to achieve lower rates of fracture, infection, and non-union is obtained by integrating the benefits of the separate components. Method: A 16-year-old female diagnosed with periosteal osteosarcoma of the left shaft femur. We performed neoadjuvant chemotherapy, limb salvage surgery consists of surgical resection and reconstruction, followed by adjuvant chemotherapy post operatively. We used Capanna procedure to salvage the femur. Result: Post-operative evaluation showed stable fixation clinically and radiologically. There is no complications observed during recovery, as both distal motor and sensory are normal eventhough the patient were still limited in the motion of the hip and knee at the time due to post-operative pain. Discussion: Cappana procedure has been known as a novel surgical method that could decrease the risk of complications results from classic reconstruction method, such as fracture, non-union, and infection. Conclusion: Modified Cappana procedure which introduce the use liquid nitorgen-recycled autograft from the resected affected bone as a peripheral shell supporting a centrally placed vascularized fibular graft to fill the massive bone defect left by surgical resection, had successfully performed in our patient whom previously diagnosed with periosteal osteosarcoma of femoral shaft. © 2021 |
Modified Capanna procedure; Periosteal osteosarcoma; Vascularized fibular graft |
cisplatin; doxorubicin; ifosfamide; mesna; adjuvant chemotherapy; adolescent; Article; bone defect; bone graft; capanna procedure; case report; clinical article; female; femur; follow up; hemosiderin laden macrophage; hip; histopathology; human; human tissue; knee; limb salvage; long term survival; mitosis rate; neoadjuvant chemotherapy; nuclear magnetic resonance imaging; open biopsy; osteosarcoma; pain; periosteum; physical examination; postoperative pain; radiodiagnosis; range of motion; saphenous nerve; superficial femoral artery; supine position; surgical technique; thigh |
Elsevier Ltd |
22102612 |
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Article |
Q3 |
232 |
17549 |
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