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212 |
Librianto D., Aprilya D. |
57192894799;57193710642; |
Cantilever method for severe kyphotic deformity correction in spondylitis tuberculosis: A technical note and literature review |
2021 |
Annals of Medicine and Surgery |
69 |
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102764 |
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2 |
https://www.scopus.com/inward/record.uri?eid=2-s2.0-85113387050&doi=10.1016%2fj.amsu.2021.102764&partnerID=40&md5=65a7cd7e9c389e8ea978726e602d9fe3 |
Department of Orthopedic and Traumatology, Faculty of Medicine Universitas Indonesia, Fatmawati General Hospital, Jakarta, Indonesia; Department of Orthopedic and Traumatology, Faculty of Medicine Universitas Indonesia, Jakarta, Indonesia |
Librianto, D., Department of Orthopedic and Traumatology, Faculty of Medicine Universitas Indonesia, Fatmawati General Hospital, Jakarta, Indonesia; Aprilya, D., Department of Orthopedic and Traumatology, Faculty of Medicine Universitas Indonesia, Jakarta, Indonesia |
Background: The kyphotic deformity is more than just a cosmetic disfigurement. It is potentially life-threatening and disturbs the quality of life by causing cardiopulmonary dysfunction, spinal imbalance, and other associated problems. Corrective surgery is challenging but it is needed to bring the spinal balance back thus halting the progressiveness of the deformity. The cantilever technique is a gold standard to correct the sagittal plane deformity. Methods: This is a review article with some case illustrations from Author's experience. Objective: We aim to review the cantilever technique for kyphotic correction in spondylitis tuberculosis patients. Conclusion: The cantilever technique is the standard for sagittal plane deformity correction that can be applied for kyphotic deformity correction in spondylitis tuberculosis cases. Developing the safest techniques and instrumentation is crucial to achieving spinal balance with minimal risk of morbidities. © 2021 |
Cantilever method; Deformity correction; Kyphotic deformity; Spondylitis tuberculosis |
cosmetic; backache; biopsy; bone graft; cardiopulmonary insufficiency; comorbidity; decortication; deformity; follow up; gold standard; graft failure; human; kyphosis; laminectomy; morbidity; nerve injury; nuclear magnetic resonance imaging; osteotomy; pain; quality of life; Review; screw loosening; spinal cord decompression; spinal cord lesion; spine malformation; systematic review; tissue culture; tuberculous spondylitis; vascularization |
Elsevier Ltd |
20490801 |
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Review |
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391 |
12334 |
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250 |
Miraj F., Nugroho A., Dalitan I.M., Setyarani M. |
56471854400;57211502355;57226482440;55883575900; |
The efficacy of ilizarov method for management of long tibial bone and soft tissue defect |
2021 |
Annals of Medicine and Surgery |
68 |
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102645 |
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https://www.scopus.com/inward/record.uri?eid=2-s2.0-85111624016&doi=10.1016%2fj.amsu.2021.102645&partnerID=40&md5=90add1d384d132f92b578c2bb65882ad |
Pediatrics Orthopaedics and Limb Reconstruction Division, Department of Orthopaedics and Traumatology, Fatmawati General Hospital, Jakarta, Indonesia; Resident of Orthopaedics and Traumatology Department, Dr. Cipto Mangunkusumo Hospital, Jakarta, Indonesia/ Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia |
Miraj, F., Pediatrics Orthopaedics and Limb Reconstruction Division, Department of Orthopaedics and Traumatology, Fatmawati General Hospital, Jakarta, Indonesia; Nugroho, A., Resident of Orthopaedics and Traumatology Department, Dr. Cipto Mangunkusumo Hospital, Jakarta, Indonesia/ Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Dalitan, I.M., Resident of Orthopaedics and Traumatology Department, Dr. Cipto Mangunkusumo Hospital, Jakarta, Indonesia/ Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Setyarani, M., Resident of Orthopaedics and Traumatology Department, Dr. Cipto Mangunkusumo Hospital, Jakarta, Indonesia/ Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia |
Introduction: Patients with open fracture Gustillo-Anderson grade 3 had undergone several surgical procedures, but still ended up with expose long dead bone or infected. Illizarov method was used to address long bone and soft tissue defect after re-debridement with radical resection of long dead bone or infected segment. Methods: We included 14 patients (mean age: 30.86 ± 11.49) with non-union tibial fracture with long dead and infected bone segment who had undergone several debridement, bone grafting or spacer and soft tissue closure procedure due to open fracture of tibia grade 3. The subjects underwent re-debridement with radical resection of dead or infected bone segment followed by Illizarov method to perform bone transport procedure for bone defect filling and simultaneously restore severe soft tissue loss and bone lengthening procedure. Results: All subjects had achieved satisfactory results with mean docking period of bone transport 3.78 ± 0.54 months, union time at the docking side 7 (5.5–9) months. Soft tissue was covered and no recurrence of infection. Three subjects had Leg Length Discrepancy (LLD) of 1 cm, whereas the remaining had zero discrepancy. No significant pain was observed at final follow-up and 4 patients had ankle joint stiffness. Conclusion: The Illizarov method can effectively address long bone and soft tissue defects by distraction osteogenesis through bone transport procedure that filling the defect gradually without bone graft and simultaneously enhancing soft tissue closure without tertiary soft tissue procedure subsequently followed with bone lengthening procedure to correct the limb length discrepancy. © 2021 |
Illizarov method; Long tibial bone defect; Non-union fracture of tibia; Soft tissue defect |
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Elsevier Ltd |
20490801 |
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Article |
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391 |
12334 |
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253 |
Reksodiputro M.H., Hutauruk S.M., Koento T., Fardizza F., Hakim R.Y.R., Audindra S., Yosia M. |
35090488800;57205105620;35090124600;55091031700;57226286398;57222006228;57204933098; |
Randomised clinical trial: Effect of administering platelet-rich fibrin to autologous fat tissue in injection laryngoplasty for vocal cord paralysis |
2021 |
Annals of Medicine and Surgery |
68 |
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102564 |
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https://www.scopus.com/inward/record.uri?eid=2-s2.0-85111006340&doi=10.1016%2fj.amsu.2021.102564&partnerID=40&md5=55d6b3d1b486bec46a872ef4e755dd23 |
Facial Plastic Reconstructive Division, Department of Otorhinolaryngology - Head and Neck Surgery, Faculty of Medicine, Universitas Indonesia, Dr. Cipto Mangunkusumo Hospital Jakarta, Indonesia; Larynx Pharynx Division, Department of Otorhinolaryngology - Head and Neck Surgery, Faculty of Medicine, Universitas Indonesia, Dr. Cipto Mangunkusumo Hospital Jakarta, Indonesia; Department of Otorhinolaryngology - Head and Neck Surgery, Faculty of Medicine, Universitas Indonesia, Dr. Cipto Mangunkusumo Hospital Jakarta, Indonesia; Faculty of Medicine, Universitas Indonesia, Dr. Cipto Mangunkusumo Hospital Jakarta, Indonesia |
Reksodiputro, M.H., Facial Plastic Reconstructive Division, Department of Otorhinolaryngology - Head and Neck Surgery, Faculty of Medicine, Universitas Indonesia, Dr. Cipto Mangunkusumo Hospital Jakarta, Indonesia; Hutauruk, S.M., Larynx Pharynx Division, Department of Otorhinolaryngology - Head and Neck Surgery, Faculty of Medicine, Universitas Indonesia, Dr. Cipto Mangunkusumo Hospital Jakarta, Indonesia; Koento, T., Facial Plastic Reconstructive Division, Department of Otorhinolaryngology - Head and Neck Surgery, Faculty of Medicine, Universitas Indonesia, Dr. Cipto Mangunkusumo Hospital Jakarta, Indonesia; Fardizza, F., Larynx Pharynx Division, Department of Otorhinolaryngology - Head and Neck Surgery, Faculty of Medicine, Universitas Indonesia, Dr. Cipto Mangunkusumo Hospital Jakarta, Indonesia; Hakim, R.Y.R., Department of Otorhinolaryngology - Head and Neck Surgery, Faculty of Medicine, Universitas Indonesia, Dr. Cipto Mangunkusumo Hospital Jakarta, Indonesia; Audindra, S., Faculty of Medicine, Universitas Indonesia, Dr. Cipto Mangunkusumo Hospital Jakarta, Indonesia; Yosia, M., Faculty of Medicine, Universitas Indonesia, Dr. Cipto Mangunkusumo Hospital Jakarta, Indonesia |
The vocal cord in humans is essential in producing voice used in communication and interaction between us. Vocal cord paralysis causes dysphonia, which interferes with communication, causing disruptions towards social activity and daily activities. One of the managements for vocal cord paralysis is medialization and augmentation of the vocal cord through injection laryngoplasty. Autologous fat is one of the best fillers used in this procedure, but it is highly absorbable and can be reabsorbed very quickly when injected into body tissues. Platelet Rich Fibrin (PRF) is a biomaterial consisting of growth factors that are thought to improve fat tissue viability by increasing adipogenesis and angiogenesis. Improvement in fat viability will improve clinical outcomes after the laryngoplasty procedure, potentially reducing the number of repeated injections needed to achieve a satisfactory resolution to vocal cord paralysis. The study evaluates a combination of PRF and autologous microlobular fat compared with autologous microlobular fat alone on laryngoplasty. This single-blinded randomised control trial recruit a total of 18 patients, which are then randomised into the treatment and control groups. The evaluation was done via computerized acoustic analysis/Multidimensional Voice Program (MDVP) parameters and maximum phonation time. The MDVP results and maximum phonation time in both groups showed clinical improvement after the operation with no statistically significant differences. © 2021 The Authors |
Autologous fat; Injection laryngoplasty; Platelet-rich fibrin; Vocal cord paralysis |
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Elsevier Ltd |
20490801 |
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Article |
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391 |
12334 |
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310 |
Situmorang H., Hestiantoro A., Purbadi S., Flamandita D., Sahlan M. |
57195939562;8743255100;6505677307;57216766308;57189182661; |
IN-SILICO dynamic analysis of Sulawesi propolis as anti-endometriosis drug: Interaction study with TNF alpha receptor, NF-kB, estrogen receptor, progesterone receptor and prostaglandin receptor |
2021 |
Annals of Medicine and Surgery |
67 |
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102459 |
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https://www.scopus.com/inward/record.uri?eid=2-s2.0-85109547312&doi=10.1016%2fj.amsu.2021.102459&partnerID=40&md5=0f7d6fdeda084de97c22a80f60f7b2a7 |
Department of Obstetrics and Gynecology Faculty of Medicine Universitas Indonesia – Dr Cipto Mangunkusumo National Referral Hospital, Jl. Salemba Raya No. 6, Central Jakarta, Jakarta Capital Special Region 10430, Indonesia; Department of Chemical Engineering, Faculty of Engineering, Universitas Indonesia, Jl. Fuad Hasan, Pancoran MAS, Kukusan, Beji, Depok City, West Java 16424, Indonesia |
Situmorang, H., Department of Obstetrics and Gynecology Faculty of Medicine Universitas Indonesia – Dr Cipto Mangunkusumo National Referral Hospital, Jl. Salemba Raya No. 6, Central Jakarta, Jakarta Capital Special Region 10430, Indonesia; Hestiantoro, A., Department of Obstetrics and Gynecology Faculty of Medicine Universitas Indonesia – Dr Cipto Mangunkusumo National Referral Hospital, Jl. Salemba Raya No. 6, Central Jakarta, Jakarta Capital Special Region 10430, Indonesia; Purbadi, S., Department of Obstetrics and Gynecology Faculty of Medicine Universitas Indonesia – Dr Cipto Mangunkusumo National Referral Hospital, Jl. Salemba Raya No. 6, Central Jakarta, Jakarta Capital Special Region 10430, Indonesia; Flamandita, D., Department of Chemical Engineering, Faculty of Engineering, Universitas Indonesia, Jl. Fuad Hasan, Pancoran MAS, Kukusan, Beji, Depok City, West Java 16424, Indonesia; Sahlan, M., Department of Chemical Engineering, Faculty of Engineering, Universitas Indonesia, Jl. Fuad Hasan, Pancoran MAS, Kukusan, Beji, Depok City, West Java 16424, Indonesia |
Introduction: Endometriosis is a disease that impacts around 10% of all women in reproductive age, with pelvic pain and infertility as its main clinical features. Current medical treatment targeting lowering estrogen activity has not shown sufficient result due its side effects and reproductive function suppression. Propolis has been widely studied, showing anti inflammation and pro-apoptosis property, that could potentially be used in the treatment of endometriosis. This study investigates the interaction between Sulawesi Propolis’ active components and receptors and protein related to endometriosis pathogenesis. Methods: Active components of Sulawesi Propolis were initially identified with their targeted protein receptors. Lipinski rules were used to screen potential components. The ligands and proteins were tested using Autodock program to predict the most active compound and possible binding sites between propolis and some target proteins associated with inflammatory and apoptotic activity in endometriosis models. Receptor modelling is then performed using Swiss-Model. Results: These active components of Sulawesi Propolis showed a strong binding potential towards TNF- α, NF-kb, Estrogen-α, Estrogen-β, progesterone B, PGE2 EP2 and EP3 subtype respectively: Sanggenon C, Sanggenon H, Epicryptoacetalide, Chrysin-7-O-β-D-glucopyranodside, Irilone, Polydatin and Epicryptoacetalide. Compared to its negative ligand, Sulawesi Propolis displayed a stronger binding capacity to TNF-α, Estrogen-α, and Progesterone B receptors. Conclusion: Sulawesi Propolis has the ability to interact with receptors related to reproductive function, apoptotic reactions and inflammatory processes, a significant factor associated with the pathogenesis of endometriosis. © 2021 |
Docking; Endometriosis; Estrogen receptor; In silico; NF-kB; Progesterone receptor; Propolis; Prostaglandin receptor; TNF alpha Receptor |
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Elsevier Ltd |
20490801 |
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391 |
12334 |
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316 |
Widodo D.W., Dewi D.J., Ranakusuma R.W., Irawati Y. |
56644646600;57219323765;57189729404;57201260313; |
Evaluation of 3 and 2-point internal fixation in the management of zygomaticomaxillary complex fractures: Case report |
2021 |
Annals of Medicine and Surgery |
67 |
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102539 |
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1 |
https://www.scopus.com/inward/record.uri?eid=2-s2.0-85109176909&doi=10.1016%2fj.amsu.2021.102539&partnerID=40&md5=aa5581548a2394f973a5958f289f0999 |
Department of Otorhinolaryngology, Head and Neck Surgery, Faculty of Medicine Universitas Indonesia, Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Clinical Epidemiology and Evidence-Based Medicine Unit, Faculty of Medicine Universitas Indonesia, Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Department of Ophthalmology, Faculty of Medicine Universitas Indonesia, Cipto Mangunkusumo Hospital, Jakarta, Indonesia |
Widodo, D.W., Department of Otorhinolaryngology, Head and Neck Surgery, Faculty of Medicine Universitas Indonesia, Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Dewi, D.J., Department of Otorhinolaryngology, Head and Neck Surgery, Faculty of Medicine Universitas Indonesia, Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Ranakusuma, R.W., Clinical Epidemiology and Evidence-Based Medicine Unit, Faculty of Medicine Universitas Indonesia, Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Irawati, Y., Department of Ophthalmology, Faculty of Medicine Universitas Indonesia, Cipto Mangunkusumo Hospital, Jakarta, Indonesia |
Introduction: The ZMC has a prominent shape compared to other parts in the midfacial region, thus small injuries will generate fractures in the ZMC. The management of ZMC fracture depends on the fracture deformity and the surgeon's considerations. Various studies have revealed the success of ZMC reconstruction with one fixation point to 4 fixation points fitting to the tetrapod shape. Case report: We report two cases of ZMC fractures which comparing the efficacy of 3- and 2-point internal fixations for improving clinical outcomes The first patient underwent ORIF which placed at 2 fixation points, the first point in the left ZF suture and the second point in the left ZMB. The second patient underwent ORIF reconstruction at 3 fixation points, the first point in the right inferior orbital rim, the second point in the right ZF suture, and the third point in the right ZMB. Discussion: The most common surgical approach for ZMC fractures is through a gingivobuccal groin incision. This approach is for body exposure of the ZMB, which is the main buttress. The 3-point internal fixation improved the postoperative clinical outcome of fracture fragment stability compared to two-point fixation, but the mean malar height projection, vertical dystopia, and enophthalmos were not different between the two fixation methods. Conclusion: Three-point internal fixation can improve the clinical outcome of fracture fragment stability compared to 2-point fixation; however, it has a mean operative duration 22.2 minutes longer than 2-point fixation, so its application must be considered during the COVID-19 pandemic. © 2021 The Authors |
Case report; Internal fixation; Zygomatic fracture; Zygomaticomaxillary fracture |
adult; Article; cartilage graft; case report; clinical article; comparative effectiveness; computer assisted tomography; coronavirus disease 2019; endotracheal intubation; enophthalmos; female; general anesthesia; heterotopia; human; inguinal region; maxilla fracture; maxillofacial surgery; nose cavity; open fracture reduction; osteosynthesis; pandemic; physical examination; visual acuity; zygoma arch fracture |
Elsevier Ltd |
20490801 |
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Article |
Q3 |
391 |
12334 |
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317 |
Hutauruk S.M., Hermani B., Monasari P. |
57205105620;14325051100;57224812004; |
Role of chlorhexidine on tracheostomy cannula decontamination in relation to the growth of Biofilm-Forming Bacteria Colony- a randomized controlled trial study |
2021 |
Annals of Medicine and Surgery |
67 |
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102491 |
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https://www.scopus.com/inward/record.uri?eid=2-s2.0-85108345034&doi=10.1016%2fj.amsu.2021.102491&partnerID=40&md5=a3d916bc24eff149d6342e51ea55083d |
ENT-Head and Neck Department, Faculty of Medicine, Universitas Indonesia-Cipto Mangunkusumo National Hospital, Jalan Diponegoro No. 71, Jakarta Pusat, Jakarta, 10430, Indonesia |
Hutauruk, S.M., ENT-Head and Neck Department, Faculty of Medicine, Universitas Indonesia-Cipto Mangunkusumo National Hospital, Jalan Diponegoro No. 71, Jakarta Pusat, Jakarta, 10430, Indonesia; Hermani, B., ENT-Head and Neck Department, Faculty of Medicine, Universitas Indonesia-Cipto Mangunkusumo National Hospital, Jalan Diponegoro No. 71, Jakarta Pusat, Jakarta, 10430, Indonesia; Monasari, P., ENT-Head and Neck Department, Faculty of Medicine, Universitas Indonesia-Cipto Mangunkusumo National Hospital, Jalan Diponegoro No. 71, Jakarta Pusat, Jakarta, 10430, Indonesia |
Background: Regular cleaning of the cannula in the trachea is very important for infection prevention. How to wash the tracheal cannula which is good to reduce the possibility of colonies of biofilm-forming bacteria and the growth of bacterial and the pattern of bacterial on the tracheal cannula is still unknown. This study aims to evaluate the efficacy of decontamination of the tracheal cannula using chlorhexidine and NaCl 0.9% in patients using the tracheal cannula to decrease biofilm-forming bacterial colony. Methods: 40 subjects were grouped into 20 subjects in the control group washing the cannula using 0.9% NaCl and the interventional group washing cannula using and with 2.5% chlorhexidine solution and 0.9% NaCl. This study used a parallel randomized controlled trial of 2 groups with a single blinded. Results: 40 subjects studied, 17 subjects (85%) each group produced biofilm-forming bacteria prior to intervention. After intervention in the study group, 15 subjects were biofilm negative and 5 biofilm positive subjects p = 0.001. The most common bacteria found in the control group is Pseudomonas aeruginosa, while in the study group some bacteria such as Acinetobacter sp. and Proteus mirabilis. Amoxicilin-Clavulanate had the highest resistance to biofilm forming bacteria in both groups. Piperacillin, ceftazidime, ciprofloxacin and meropenem have the highest sensitivity to biofilm-forming bacteria. Conclusion: There was a significant decrease in the number of colonies that produced biofilm in the tracheal cannula in the study group compared to the control group in tracheal cannula washing. © 2021 The Authors |
Bacteria colony; Biofilms; Chlorhexidine; Tracheostomy cannulae |
amoxicillin plus clavulanic acid; ceftazidime; chlorhexidine; ciprofloxacin; meropenem; piperacillin; sultamicillin; adult; aged; antibacterial activity; antibiotic resistance; Article; bacterial growth; bacterium colony; biofilm; clinical article; controlled study; decontamination; diabetes mellitus; Escherichia coli; human; hypertension; malnutrition; Proteus mirabilis; Pseudomonas aeruginosa; randomized controlled trial; single blind procedure; Staphylococcus aureus; tracheostomy |
Elsevier Ltd |
20490801 |
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Article |
Q3 |
391 |
12334 |
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370 |
Purbadi S., Rustamadji P., Purwoto G., Kusuma F., Putra A.D., Scovani L., Sianturi E.T. |
6505677307;55321572200;14720170400;57192911548;57208996180;57223440213;57223430479; |
Skin metastases originated from cervical cancer: A rare case report |
2021 |
Annals of Medicine and Surgery |
66 |
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102363 |
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https://www.scopus.com/inward/record.uri?eid=2-s2.0-85105852603&doi=10.1016%2fj.amsu.2021.102363&partnerID=40&md5=6edeeefd66a3289a6bb1540f0adc31fe |
Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, dr.Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Department of Pathology Anatomy, Faculty of Medicine, Universitas Indonesia, dr. Cipto Mangunkusumo National Referral Hospital, Indonesia |
Purbadi, S., Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, dr.Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Rustamadji, P., Department of Pathology Anatomy, Faculty of Medicine, Universitas Indonesia, dr. Cipto Mangunkusumo National Referral Hospital, Indonesia; Purwoto, G., Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, dr.Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Kusuma, F., Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, dr.Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Putra, A.D., Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, dr.Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Scovani, L., Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, dr.Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Sianturi, E.T., Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, dr.Cipto Mangunkusumo Hospital, Jakarta, Indonesia |
Introduction: Metastases in cervical cancer could be spread through direct local invasion, lymphatic dissemination, or hematogenous dissemination. The most common sites of distant metastases are lungs, bone, and liver. Skin metastases from cervical cancer are categorized as a rare occurrence of metastases. This rarity of the cases has led us to report it. Case description: A 66-year-old multiparous woman diagnosed with stage IIA cervical cancer seven years ago, then she came into our outpatient clinic complained about a brownish white color mass on the left side of the neck that keeps getting bigger over time came from a skin lesion. The lesion was first treated with topical steroid but there was no improvement. Biopsy was done and the result showed a carcinoma metastasis that led to adenosquamous carcinoma or cervical adenocarcinoma. The patient went through chemoradiation with biosensitizer paclitaxel 120 mg/m2 for six cycles, which began in August 2019 until October 2019. The treatment progress showed a promising result. We observed the patient during treatment until two months after finishing the treatment. At the last visit, the patient came to our outpatient clinic, the mass size decreased significantly, and the skin showed an excellent regeneration sign. Conclusion: The physicians should always consider the patient's history and pay more attention to skin lesions in patients with a history of cervical cancer. The physicians should also perform a thorough physical examination and biopsy to confirm the diagnosis. © 2021 The Author(s) |
Cervical cancer; Skin lesion; Skin metastasis |
paclitaxel; adenocarcinoma; adenosquamous carcinoma; aged; anemia; Article; attention; body weight; brain metastasis; cancer patient; case report; chemoradiotherapy; clinical article; cutaneous leishmaniasis; distant metastasis; drug industry; female; histopathology; human; human tissue; hysterectomy; laparotomy; mammography; metastasis; multipara; ovariectomy; physical examination; physician; regeneration; sexual behavior; skin defect; skin metastasis; thrombocytopenia; uterine cervix adenocarcinoma; uterine cervix cancer; vaginal secretion |
Elsevier Ltd |
20490801 |
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Article |
Q3 |
391 |
12334 |
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372 |
Reksodiputro M.H., Harahap A.R., Siregar N.C., Malik S.G., Bashirudin J., Boesoirie M.T.S., Widodo D.W., Iljanto S., Sajuthi D., Sukrisman L., Yosia M. |
35090488800;6507325543;6508087790;7402973374;57223288901;57223301168;56644646600;57223273746;6603075144;8661764000;57204933098; |
Comparison between PRP and PRFM on FTSG healing profile: Macroscopic, microscopic and ELISA evaluation |
2021 |
Annals of Medicine and Surgery |
66 |
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102350 |
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https://www.scopus.com/inward/record.uri?eid=2-s2.0-85105502675&doi=10.1016%2fj.amsu.2021.102350&partnerID=40&md5=632e6c1f802e9603336c9a0770ecc410 |
Department of Otorhinolaryngology-Head and Neck Surgery, Faculty of Medicine, Universitas Indonesia, dr. Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Department of Clinical Pathology, Faculty of Medicine, Universitas Indonesia, dr. Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Department of Pathology Anatomy, Faculty of Medicine, Universitas Indonesia, dr. Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Eijkman Institute for Molecular Biology, Jakarta, Indonesia; Department of Otorhinolaryngology-Head and Neck Surgery, Faculty of Medicine, University of Padjajaran, Hasan Sadikin Hospital, Bandung, Indonesia; Faculty of Public Health, Centre for Health Administration, Management and Policy, Universitas Indonesia, Jakarta, Indonesia; Department of Clinics, Reproduction, and Pathology, Faculty of Veterinary Medicine, Institute Pertanian Bogor, Bogor, Indonesia; Department of Internal Medicine, Faculty of Medicine, Universitas Indonesia, dr. Cipto Mangunkusumo Hospital, Jakarta, Indonesia |
Reksodiputro, M.H., Department of Otorhinolaryngology-Head and Neck Surgery, Faculty of Medicine, Universitas Indonesia, dr. Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Harahap, A.R., Department of Clinical Pathology, Faculty of Medicine, Universitas Indonesia, dr. Cipto Mangunkusumo Hospital, Jakarta, Indonesia, Eijkman Institute for Molecular Biology, Jakarta, Indonesia; Siregar, N.C., Department of Pathology Anatomy, Faculty of Medicine, Universitas Indonesia, dr. Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Malik, S.G., Eijkman Institute for Molecular Biology, Jakarta, Indonesia; Bashirudin, J., Department of Otorhinolaryngology-Head and Neck Surgery, Faculty of Medicine, Universitas Indonesia, dr. Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Boesoirie, M.T.S., Department of Otorhinolaryngology-Head and Neck Surgery, Faculty of Medicine, University of Padjajaran, Hasan Sadikin Hospital, Bandung, Indonesia; Widodo, D.W., Department of Otorhinolaryngology-Head and Neck Surgery, Faculty of Medicine, Universitas Indonesia, dr. Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Iljanto, S., Faculty of Public Health, Centre for Health Administration, Management and Policy, Universitas Indonesia, Jakarta, Indonesia; Sajuthi, D., Department of Clinics, Reproduction, and Pathology, Faculty of Veterinary Medicine, Institute Pertanian Bogor, Bogor, Indonesia; Sukrisman, L., Department of Internal Medicine, Faculty of Medicine, Universitas Indonesia, dr. Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Yosia, M., Department of Otorhinolaryngology-Head and Neck Surgery, Faculty of Medicine, Universitas Indonesia, dr. Cipto Mangunkusumo Hospital, Jakarta, Indonesia |
Background: Studies had shown the benefit of PRFM and PRP in wound healing but their use in skin graft healing was rarely studied. This study aims to compare the use of PRP and PRFM in accelerating wound healing process of skin full-thickness skin graft (FTSG). Materials and methods: Five pigs were used to look at the wound healing effect of PRP and PRFM usage prior to FTSG implantation. Subsequent punch biopsies were then conducted on the 1st, 3rd, 7th, 14th, and 30th day to obtain samples for macroscopic (skin color), extracellular matrix (collagen), microscopic (PMN, macrophage, and fibroblast), and ELISA (TGFβ1 and PDGF) analysis to determine the level of wound healing activity. ImageJ software was used to photograph for macroscopic and extracellular matrix analysis. Results: Macroscopic, extracellular matrix, and ELISA evaluation show no significant difference in FTSG survival rates for all treatment groups. Microscopic examination showed an increase in PMN, macrophage, and fibroblast levels with PRFM application showing higher increases in all observed microscopic variables compared to PRP and control. Conclusion: This study observed that both PRFM and PRP as autologous platelet preparation accelerate wound healing in FTSG, with PRFM being superior due to the higher number of PMN, macrophage, and fibroblast. © 2021 The Authors |
FTSG; PRFM; PRP; Wound healing |
atropine; collagen; collagen type 1; hemoglobin; isoflurane; ketamine; lidocaine; platelet derived growth factor; platelet-rich fibrin; transforming growth factor beta1; xylazine; animal experiment; animal model; animal tissue; Article; enzyme linked immunosorbent assay; exosome; extracellular matrix; female; fibroblast; full thickness skin graft; glomerulus filtration rate; graft survival; histology; macrophage; male; microscopy; neutrophil; nonhuman; platelet-rich plasma cell; punch biopsy; scientific literature; skin injury; survival rate; thrombocyte; wound healing |
Elsevier Ltd |
20490801 |
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391 |
12334 |
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410 |
Solichin I., Sandjaya G., Prabowo I., Dwi Putra N.H., Rhatomy S. |
57202813479;57223086553;57221098612;57223086083;57204509883; |
The lateral curved osteotomy for cubitus varus deformity in children: A case report and literature review |
2021 |
Annals of Medicine and Surgery |
65 |
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102315 |
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https://www.scopus.com/inward/record.uri?eid=2-s2.0-85104767442&doi=10.1016%2fj.amsu.2021.102315&partnerID=40&md5=d2cf2846c9fa539b567bea0b5a8e358f |
Orthopaedic Hospital Purwokerto, Network Hospital of Department Orthopaedics and Traumatology, Cipto Mangunkusumo General Hospital, Indonesia; Soedarso Hospital Pontianak, Network Hospital of Department Orthopaedics and Traumatology, Cipto Mangunkusumo General Hospital, Indonesia; Department of Orthopaedics and Traumatology, Cipto Mangunkusumo General Hospital, Faculty of Medicine Universitas Indonesia, Jakarta, Indonesia; Sport and Adult Reconstruction Division, Department of Orthopedics and Traumatology, Dr. Soeradji Tirtonegoro General Hospital, Klaten, Indonesia; Faculty of Medicine, Public Health, and Nursing, Universitas Gadjah Mada, Yogyakarta, Indonesia |
Solichin, I., Orthopaedic Hospital Purwokerto, Network Hospital of Department Orthopaedics and Traumatology, Cipto Mangunkusumo General Hospital, Indonesia; Sandjaya, G., Soedarso Hospital Pontianak, Network Hospital of Department Orthopaedics and Traumatology, Cipto Mangunkusumo General Hospital, Indonesia; Prabowo, I., Department of Orthopaedics and Traumatology, Cipto Mangunkusumo General Hospital, Faculty of Medicine Universitas Indonesia, Jakarta, Indonesia; Dwi Putra, N.H., Department of Orthopaedics and Traumatology, Cipto Mangunkusumo General Hospital, Faculty of Medicine Universitas Indonesia, Jakarta, Indonesia; Rhatomy, S., Sport and Adult Reconstruction Division, Department of Orthopedics and Traumatology, Dr. Soeradji Tirtonegoro General Hospital, Klaten, Indonesia, Faculty of Medicine, Public Health, and Nursing, Universitas Gadjah Mada, Yogyakarta, Indonesia |
Introduction: Cubitus varus deformity after malunited supracondylar humerus fracture has various surgical techniques, implant configurations, and approaches. We describe a combination of French and Dome osteotomy and novel internal fixation technique to deliver an easy, safe, fast and reproducible result based on the current best evidence. Presentation of case: Two cases of malunited supracondylar humerus are described. The first case involves a 3-year-old girl who presented with outstretched and supinated left arm after falling during bike riding 3 weeks earlier. We found no abnormality in radial and median nerve function, but the left arm radiographs showed a callus formation and the early stages of a malunited fracture of the supracondylar humerus. We waited two months for further radiographic evaluation and the radiographs showed the malunited supracondylar humerus with elbow flexion of only 105° and elbow hyperextension of 20°. The cubitus varus was recorded with clinical carrying angle of varus 10°. We used a combination of original French and Dome osteotomy, lateral approach, and our novel fixation technique with excellent results. The second case involved a 8-year-old boy with malunited right elbow and the surgery was done in the same manner, with the result of restoration to normal elbow range of motion. We also assessed the pain score and disabilities of the arm, shoulder and hand (DASH) score and recorded satisfactory results. Conclusions: The combination of French and Dome osteotomy for treatment of cubitus varus deformity can provide an easy, safe, and reproducible result. © 2021 The Author(s) |
Cubitus varus deformity; Dome osteotomy; French osteotomy; Malunited supracondylar humerus |
Article; callus; case report; cerclage; child; clinical article; Disabilities of the Arm, Shoulder and Hand (score); disability; elbow flexion; elbow radiography; female; follow up; human; humeral supracondylar fracture; iatrogenic disease; male; nerve function; open reduction (procedure); osteotomy; pain; pain assessment; preschool child; range of motion; school child; varus deformity |
Elsevier Ltd |
20490801 |
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Article |
Q3 |
391 |
12334 |
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476 |
Kamal A.F., Abubakar I., Salamah T. |
56648996700;57204179162;57195380322; |
Alkaline phosphatase, lactic dehidrogenase, inflammatory variables and apparent diffusion coefficients from MRI for prediction of chemotherapy response in osteosarcoma. A cross sectional study |
2021 |
Annals of Medicine and Surgery |
64 |
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102228 |
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https://www.scopus.com/inward/record.uri?eid=2-s2.0-85102644624&doi=10.1016%2fj.amsu.2021.102228&partnerID=40&md5=fd665964a20c5345b17f1145f1383619 |
Department of Orthopaedic and Traumatology Faculty of Medicine Universitas Indonesia/ Cipto Mangunkusumo General Hospital, Jakarta, Indonesia; Division of Orthopaedic and Traumatology-Department of Surgery Faculty of Medicine Universitas Syiah Kuala/ Zainoel Abidin General Hospital, Banda Aceh, Indonesia; Department of Radiology Faculty of Medicine Universitas Indonesia/Cipto Mangunkusumo, General Hospital, Jakarta, Indonesia |
Kamal, A.F., Department of Orthopaedic and Traumatology Faculty of Medicine Universitas Indonesia/ Cipto Mangunkusumo General Hospital, Jakarta, Indonesia; Abubakar, I., Department of Orthopaedic and Traumatology Faculty of Medicine Universitas Indonesia/ Cipto Mangunkusumo General Hospital, Jakarta, Indonesia, Division of Orthopaedic and Traumatology-Department of Surgery Faculty of Medicine Universitas Syiah Kuala/ Zainoel Abidin General Hospital, Banda Aceh, Indonesia; Salamah, T., Department of Radiology Faculty of Medicine Universitas Indonesia/Cipto Mangunkusumo, General Hospital, Jakarta, Indonesia |
Background: This present study aimed to assess if clinical, laboratory and MRI were an accurate benchmark in assessing the effectiveness of neoadjuvant chemotherapy in osteosarcoma patients. Methods: This was an observational analytic study with a cross-sectional design. We correlated among clinical, laboratory and magnetic resonance imaging (MRI) data before and after neoadjuvant chemotherapy; and percentage of tumor necroses from osteosarcoma patients during the period between January 2017–July 2019. Results: Of the 58 patients included in this study, 38 were male and 20 were female aged 5 - 67 years (mean: 16-year-old. 37(63.8%) patients underwent neoadjuvant chemotherapy with CAI regimens and 13 (36.2%) with CA regiments. The tumors were classified as stage IIB in 43 (74.1%) patients and stage III in 15 (25.9%) patients. Wilcoxon test showed significant differences between alkaline phosphatase (ALP), erythrocyte sedimentation rate (ESR), and neutrophil to lymphocyte ratio (NLR) before and after neoadjuvant chemotherapy in the poor-response group. We found no significant difference between lactic dehydrogenase (LDH) and lymphocyte-to-monocyte ratio (LMR) before and after neoadjuvant chemotherapy in the good-response group. MRI revealed decreased tumor volume in patients in the good-response to chemotherapy. Conclusion: We demonstrated that ALP level was statistically significant in the poor-response group. We also found that LDH value before neoadjuvant chemotherapy had a strong correlation with degree of necrosis and could be used as a predictive indicator. MRI plays an important role in evaluating tumor volumes and preoperative radiological changes to predict histological necrosis. © 2021 |
Alkaline phospkatase; Chemotherapy; LDH; MRI Apparent diffusion coefficients; NLR,LMR; Osteosarcoma |
alanine aminotransferase; alkaline phosphatase; C reactive protein; cisplatin; doxorubicin; fluorodeoxyglucose f 18; ifosfamide; lactate dehydrogenase; adjuvant therapy; adolescent; adult; aged; analytical research; apparent diffusion coefficient; Article; cancer chemotherapy; cancer size; cancer staging; child; comparative effectiveness; computer assisted tomography; cross-sectional study; erythrocyte sedimentation rate; female; histology; human; human tissue; hypertransaminasemia; lymphocyte monocyte ratio; major clinical study; male; MSTS score; neoadjuvant chemotherapy; neutrophil lymphocyte ratio; nuclear magnetic resonance imaging; observational study; osteosarcoma; platelet lymphocyte ratio; receiver operating characteristic; retrospective study; scoring system; treatment response; |
Elsevier Ltd |
20490801 |
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Article |
Q3 |
391 |
12334 |
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