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Id	Authors	Author S Id	Title	Year	Source Title	Volume	Issue	Art No	Page Start	Page End	Cited By	Link	Affiliations	Authors With Affiliations	Abstract	Author Keywords	Index Keywords	Publisher	Issn	Pubmed Id	Document Type	Sjr Best Quartile	Sjr	Sjr Rank
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Department of Child Health, Division of Pediatric Cardiology, Dr. Moh Hoesin Hospital, Faculty of Medicine, Universitas Sriwijaya, Palembang, 30126, Indonesia; Intelligent System Research Group, Universitas Sriwijaya, Palembang, 30139, Indonesia; Department of Medicine, Dr. MohHoesin Hospital, Faculty of Medicine, Universitas Sriwijaya, Palembang, 30126, Indonesia; Department of Child Health, Division of Pediatric Cardiology, Dr. CiptoMangunkusumo Hospital, Faculty of Medicine, Universitas Indonesia, Jakarta, 10430, Indonesia(1)
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803	Nova R., Nurmaini S., Partan R.U., Putra S.T.	57210234221;26639610000;57190664693;6603587929;	Automated image segmentation for cardiac septal defects based on contour region with convolutional neural networks: A preliminary study	2021	Informatics in Medicine Unlocked	24		100601				https://www.scopus.com/inward/record.uri?eid=2-s2.0-85106348104&doi=10.1016%2fj.imu.2021.100601&partnerID=40&md5=37e5f3bcab0ef015f7441efa32757710	Department of Child Health, Division of Pediatric Cardiology, Dr. Moh Hoesin Hospital, Faculty of Medicine, Universitas Sriwijaya, Palembang, 30126, Indonesia; Intelligent System Research Group, Universitas Sriwijaya, Palembang, 30139, Indonesia; Department of Medicine, Dr. MohHoesin Hospital, Faculty of Medicine, Universitas Sriwijaya, Palembang, 30126, Indonesia; Department of Child Health, Division of Pediatric Cardiology, Dr. CiptoMangunkusumo Hospital, Faculty of Medicine, Universitas Indonesia, Jakarta, 10430, Indonesia	Nova, R., Department of Child Health, Division of Pediatric Cardiology, Dr. Moh Hoesin Hospital, Faculty of Medicine, Universitas Sriwijaya, Palembang, 30126, Indonesia; Nurmaini, S., Intelligent System Research Group, Universitas Sriwijaya, Palembang, 30139, Indonesia; Partan, R.U., Department of Medicine, Dr. MohHoesin Hospital, Faculty of Medicine, Universitas Sriwijaya, Palembang, 30126, Indonesia; Putra, S.T., Department of Child Health, Division of Pediatric Cardiology, Dr. CiptoMangunkusumo Hospital, Faculty of Medicine, Universitas Indonesia, Jakarta, 10430, Indonesia	Echocardiogram examination is important for diagnosing cardiac septal defects. With the development of AI-based technology, an echocardiogram examination previously performed manually by cardiologists can be done automatically. Automatic segmentation of cardiac septal defects can help a physician to make an initial diagnosis before referring a pediatric cardiologist for further treatment. In previous studies, automatic object segmentation using convolutional neural networks (CNNs) was one of the DL applications that have been developed for cardiac abnormalities. In this study, we propose a CNN-based U-Net architecture to automatically segment the cardiac chamber to detect abnormalities (holes) in the heart septum. In this study, echocardiogram examinations were performed on atrial septal defects (ASDs), ventricular septal defects (VSDs), atrioventricular septal defects (AVSDs), and normal hearts with patients undergoing echocardiogram examination at Moh Hoesin Hospital in Palembang. The results show that even for the relatively small number of datasets, the proposed technique can produce superior performance in the detection of the cardiac septal defects. Using the proposed segmentation model for four classes produces a pixel accuracy of 99.15%, mean intersection over union (IoU) of 94.69%, mean accuracy of 97.73%, sensitivity of 96.02%, and F1 score of 94.88%, respectively. The plots of the loss and accuracy curve show that all the errors were small, with accuracy rates reaching 99.05%, 98.62%, 99.39%, and 98.97% for ASD, VSD, AVSD, and normal heart, respectively. The comparison accuracy of contour prediction for U-Net was 99.01%, while V-Net was 93.70%. This shows that the U-Net has better accuracy than the V-Net model architecture. It can be proven that the architecture of CNNs has been successful in segmenting the cardiac chamber to detect defects in the heart septum and support the work of cardiologists. © 2021 The Authors	Cardiac septal defect; CNNs; Contour segmentation; Deep learning	adult; Article; atrioventricular septal defect; child; clinical article; clinical examination; computer assisted diagnosis; controlled study; convolutional neural network; deconvolution; deep learning; diagnostic accuracy; diagnostic test accuracy study; heart atrium septum defect; heart ventricle septum defect; human; image processing; image segmentation; pediatric patient; two dimensional echocardiography	Elsevier Ltd	23529148		Article	Q3	440	11223	View
Department of Child Health, Division of Pediatric Nephrology, Cipto Mangunkusumo General Hospital, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia(1)
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683	Puspitasari H.A., Indriasti N., Hidayati E.L.	57214119502;57310728900;57200542624;	Antihypertensive management in children: A two-years experience of indonesia's national referral hospital	2021	Anatolian Journal of Family Medicine	4	1		7	12		https://www.scopus.com/inward/record.uri?eid=2-s2.0-85117862602&doi=10.5505%2fanatoljfm.2020.18209&partnerID=40&md5=bb62f06ed1d11c2f9f176e26ae094521	Department of Child Health, Division of Pediatric Nephrology, Cipto Mangunkusumo General Hospital, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia	Puspitasari, H.A., Department of Child Health, Division of Pediatric Nephrology, Cipto Mangunkusumo General Hospital, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Indriasti, N., Department of Child Health, Division of Pediatric Nephrology, Cipto Mangunkusumo General Hospital, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Hidayati, E.L., Department of Child Health, Division of Pediatric Nephrology, Cipto Mangunkusumo General Hospital, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia	Objectives: The prevalence of hypertension (HT) in children has increased overtime. However, data related to antihypertensive options and outcomes are still limited in children, especially in Indonesia. This study aimed to describe pediatric HT cases and antihypertensive management in Cipto Mangunkusumo General Hospital (CMGH). Methods: A retrospective cross-sectional study was conducted in CMGH from January 2016 to December 2017. Inclusion criteria were children age <18 years with primary and secondary HT visiting pediatric nephrology clinic. Patients were excluded if no blood pressure records were found. Clinical and antihypertensive treatments data were recorded from medical records. Diagnosis was based on the Fourth Report classification. Results: This study included 176 children with HT. Secondary HT was found in 159 (90.3%) patients, and 82 (51.6%) of them had isolated kidney-urinary tract disease. Dual antihypertensive therapy was prescribed for 53 (30.1%) patients, whereas 55 (31.3%) patients was monotherapy. The most common antihypertensive used in monotherapy was angiotensin converting enzyme inhibitors (ACEI), received by 31 (56.3%) patients. The median duration of therapy until achievement of target blood pressure was 28.0 (1.0-365.0) days. Conclusion: Pediatric HT is an often overlooked growing medical issue. Secondary HT was found more in children compare to primary HT. Secondary etiology was suspected if HT was found in children with kidney disease. The first-line antihypertensive drug used was ACEI, as single or combination therapy. The therapeutic effect of antihypertensive drugs was expected within 28 days of treatment. © 2020 by Anatolian Journal of Family Medicine.	Antihypertensive agents; Children; Essential hypertension; Hypertension		Kare Publishing	26305593		Article	#N/A	#N/A	#N/A	View
Department of Child Health, Dr. Cipto Mangunkusumo Hospital, Faculty of Medicine, Universitas Indonesia, Indonesia; Developmental Behavioural & Community Pediatrics Division, Department of Child Health, Dr. Cipto Mangunkusumo Hospital, Faculty of Medicine, Universitas Indonesia, Indonesia; Neonatology Division, Department of Child Health, Dr. Cipto Mangunkusumo Hospital, Faculty of Medicine, Universitas Indonesia, Indonesia; Pediatric Respirology Division, Department of Child Health, Dr. Cipto Mangunkusumo Hospital, Faculty of Medicine, Universitas Indonesia, Indonesia(1)
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156	Yoanita R., Gunardi H., Rohsiswatmo R., Setyanto D.B.	57257403000;56510252700;55533574600;57203009929;	Effect of tactile–kinesthetic stimulation on growth, neurobehavior and development among preterm neonates	2021	Journal of Bodywork and Movement Therapies	28			180	186		https://www.scopus.com/inward/record.uri?eid=2-s2.0-85114826873&doi=10.1016%2fj.jbmt.2021.06.023&partnerID=40&md5=42e65f10f1f437b31aaa9dd4fdb3559e	Department of Child Health, Dr. Cipto Mangunkusumo Hospital, Faculty of Medicine, Universitas Indonesia, Indonesia; Developmental Behavioural & Community Pediatrics Division, Department of Child Health, Dr. Cipto Mangunkusumo Hospital, Faculty of Medicine, Universitas Indonesia, Indonesia; Neonatology Division, Department of Child Health, Dr. Cipto Mangunkusumo Hospital, Faculty of Medicine, Universitas Indonesia, Indonesia; Pediatric Respirology Division, Department of Child Health, Dr. Cipto Mangunkusumo Hospital, Faculty of Medicine, Universitas Indonesia, Indonesia	Yoanita, R., Department of Child Health, Dr. Cipto Mangunkusumo Hospital, Faculty of Medicine, Universitas Indonesia, Indonesia; Gunardi, H., Developmental Behavioural & Community Pediatrics Division, Department of Child Health, Dr. Cipto Mangunkusumo Hospital, Faculty of Medicine, Universitas Indonesia, Indonesia; Rohsiswatmo, R., Neonatology Division, Department of Child Health, Dr. Cipto Mangunkusumo Hospital, Faculty of Medicine, Universitas Indonesia, Indonesia; Setyanto, D.B., Pediatric Respirology Division, Department of Child Health, Dr. Cipto Mangunkusumo Hospital, Faculty of Medicine, Universitas Indonesia, Indonesia	Background: Preterm neonates are at risk of delayed growth and development. Hence, early tactile–kinesthetic stimulation (TKS) is required to improve their growth and development. Objective: To evaluate the effect of TKS on growth, neurobehavior and development among preterm neonates. Method: An interventional study was conducted from August 2015 to July 2017 in the neonatal unit of Dr. Cipto Mangunkusumo Hospital. Preterm neonates were recruited via random sampling and divided into two groups (the intervention group and control group). TKS was performed for 15 min, three times a day, for 10 days. The anthropometric measurements, neurobehavior (Dubowitz score) and development (Capute Scale score) of neonates in both groups were assessed. Results: There were 126 preterm neonates (n = 63 in each group). During the 10-day TKS period, the intervention group had a significant increment in weight and length compared to the control group (p < 0.05) at 11–14 days, at term and 3 months. Moreover, increased tone, reflexes, and improvement in behavior based on the Dubowitz score were observed during monitoring. However, the result did not differ significantly (p > 0.05). There was no significant difference in terms of cognitive and language development in both groups (Developmental Quotient of Clinical Linguistic Adaptive Milestone Scale, Developmental Quotient of Clinical Adaptive Test and Full Scale Developmental Quotient scores, p > 0.05). Conclusion: TKS was significantly effective in promoting growth, particularly weight and length, among preterm neonates. However, it did not significantly influence neurobehavior and development at 3 months of chronological age. © 2021 Elsevier Ltd	Growth; Infant behavior; Infant development; Preterm infants; Tactile perception	human; kinesthesia; newborn; prematurity; touch; Humans; Infant, Newborn; Infant, Premature; Kinesthesis; Touch	Churchill Livingstone	13608592	34776139	Article	Q1	467	10672	View
Department of Child Health, Dr. Cipto Mangunkusumo Tertiary General Hospital, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Department of Child Health, Mohammad Hoesin General Hospital, Universitas Sriwijaya, Medical School, Palembang, Indonesia(1)
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663	Mangunatmadja I., Indra R.M., Widodo D.P., Rafli A.	57195717216;57222298152;57215087823;57210824944;	Risk Factors for Drug Resistance in Epileptic Children with Age of Onset above Five Years: A Case-Control Study	2021	Behavioural Neurology	2021		9092824				https://www.scopus.com/inward/record.uri?eid=2-s2.0-85119934233&doi=10.1155%2f2021%2f9092824&partnerID=40&md5=74ddaa54df43f8e9dd4e310b0bf1246c	Department of Child Health, Dr. Cipto Mangunkusumo Tertiary General Hospital, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Department of Child Health, Mohammad Hoesin General Hospital, Universitas Sriwijaya, Medical School, Palembang, Indonesia	Mangunatmadja, I., Department of Child Health, Dr. Cipto Mangunkusumo Tertiary General Hospital, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Indra, R.M., Department of Child Health, Mohammad Hoesin General Hospital, Universitas Sriwijaya, Medical School, Palembang, Indonesia; Widodo, D.P., Department of Child Health, Dr. Cipto Mangunkusumo Tertiary General Hospital, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Rafli, A., Department of Child Health, Dr. Cipto Mangunkusumo Tertiary General Hospital, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia	Background. Children with epilepsy with onset above five years encompass distinct epidemiological and clinical characteristics that may have specific risk factors for resistance to antiseizure medications (ASMs). Studies on this age group are limited. Purpose. To identify risk factors for drug resistance in children with epilepsy with the age of onset above five years. Methods. A case-control study was conducted on children with epilepsy with the age of onset above five years visiting the Pediatric Neurology Clinic of Cipto Mangunkusumo and Mohammad Hoesin Hospital between September 2015 and August 2016. Cases consisted of drug-resistant children while control consisted of drug-responsive children according to 2010 ILAE classification. Risk factors studied include onset, number of seizures, illness duration before treatment, cause, seizure type, status epilepticus, initial and evolution of EEG, brain imaging, and initial treatment response. Results. Thirty-two pairs of children were included in the study. After logistic regression analysis, symptomatic etiology and failure to achieve early response to treatment were found to be associated with drug resistance with adjusted OR of 84.71 (95% CI: 5.18-1359.15) and 72.55 (95% CI: 7.08-743.85), respectively. Conclusion. Poor initial response to ASM and symptomatic etiology are independent risk factors for drug resistance in children with epilepsy with the age of onset above five years. © 2021 Irawan Mangunatmadja et al.		anticonvulsive agent; case control study; child; drug resistance; epilepsy; human; onset age; preschool child; risk factor; Age of Onset; Anticonvulsants; Case-Control Studies; Child; Child, Preschool; Drug Resistance; Epilepsy; Humans; Risk Factors	Hindawi Limited	09534180	34804259	Article	Q2	859	5468	View
Department of Child Health, Faculty of Medicine Public Health and Nursing, Universitas Gadjah Mada, Yogyakarta, Indonesia; Department of Pediatric, Faculty of Medicine, University of Indonesia, Jakarta, Indonesia(1)
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578	Arguni E., Karyanti M.R., Satari H.I., Hadinegoro S.R.	8520598700;56290680800;57226214366;56893685800;	Diphtheria outbreak in Jakarta and Tangerang, Indonesia: Epidemiological and clinical predictor factors for death	2021	PLoS ONE	16	2 February	e0246301			3	https://www.scopus.com/inward/record.uri?eid=2-s2.0-85100508974&doi=10.1371%2fjournal.pone.0246301&partnerID=40&md5=d5c31533e8d632bb7459927c7da0cce2	Department of Child Health, Faculty of Medicine Public Health and Nursing, Universitas Gadjah Mada, Yogyakarta, Indonesia; Department of Pediatric, Faculty of Medicine, University of Indonesia, Jakarta, Indonesia	Arguni, E., Department of Child Health, Faculty of Medicine Public Health and Nursing, Universitas Gadjah Mada, Yogyakarta, Indonesia; Karyanti, M.R., Department of Pediatric, Faculty of Medicine, University of Indonesia, Jakarta, Indonesia; Satari, H.I., Department of Pediatric, Faculty of Medicine, University of Indonesia, Jakarta, Indonesia; Hadinegoro, S.R., Department of Pediatric, Faculty of Medicine, University of Indonesia, Jakarta, Indonesia	Background In 2017, a diphtheria outbreak occurred in several provinces in Indonesia. The aim of this study was to identify predictors of mortality outcome of pediatric patients with clinical diphtheria. Methods A retrospective cohort study was conducted using patient medical records at five referral hospitals in the Province of Jakarta and one in Tangerang District, Banten Province during January 2017 to 31 August 2018. All children in the age group of 1-18 years old discharged with diagnosis of clinical diphtheria formed the study group. All anonymized patient data were evaluated for demographic issues, clinical features, immunization status, complication, laboratory profiles and outcome. Results A total of 283 patients with clinical diphtheria were included in the study group with case fatality rate of 3.5%. All mortal patients had the complication of myocarditis. Regression analyses revealed factors for predicting mortality. Incomplete primary diphtheria toxoid immunization, stridor, bull neck, leukocytosis ≥15 ×109 cells/L and thrombocytopenia ≤150 x109 cells/L in each combination for 2 predictors modeling were correlated with death. Conclusions We report key predictors of mortality in pediatric patients with clinical diphtheria. The presence of these features when admitted to the hospital must be taken into account, because they can lead to fatal outcome. © 2021 Arguni et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.		adolescent; child; cohort analysis; complication; diphtheria; epidemic; female; hospitalization; human; immunization; Indonesia; infant; male; medical record; mortality; myocarditis; preschool child; regression analysis; retrospective study; vaccination; Adolescent; Child; Child, Preschool; Cohort Studies; Diphtheria; Disease Outbreaks; Female; Hospitalization; Humans; Immunization; Indonesia; Infant; Male; Medical Records; Myocarditis; Regression Analysis; Retrospective Studies; Vaccination	Public Library of Science	19326203	33539453	Article	Q1	990	4434	View
Department of Child Health, Faculty of Medicine Universitas Indonesia, Cipto Mangunkusumo Hospital, Jakarta, Indonesia(1)
No records
923	Hidayati E.L., Utami M.D., Rohsiswatmo R., Tridjaja B.	57200542624;57217291921;55533574600;6504507193;	Cystatin C compared to serum creatinine as a marker of acute kidney injury in critically ill neonates	2021	Pediatric Nephrology	36	1		181	186	3	https://www.scopus.com/inward/record.uri?eid=2-s2.0-85087002032&doi=10.1007%2fs00467-020-04668-3&partnerID=40&md5=45ca525dfa7a5bd6f6f0c1d995fe7930	Department of Child Health, Faculty of Medicine Universitas Indonesia, Cipto Mangunkusumo Hospital, Jakarta, Indonesia	Hidayati, E.L., Department of Child Health, Faculty of Medicine Universitas Indonesia, Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Utami, M.D., Department of Child Health, Faculty of Medicine Universitas Indonesia, Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Rohsiswatmo, R., Department of Child Health, Faculty of Medicine Universitas Indonesia, Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Tridjaja, B., Department of Child Health, Faculty of Medicine Universitas Indonesia, Cipto Mangunkusumo Hospital, Jakarta, Indonesia	Background: Acute kidney injury (AKI) is one of the most common causes of neonatal morbidity and mortality. Diagnosing AKI in neonates is challenging as it lacks specific signs, symptoms, and biomarkers. However, detecting AKI in critically ill neonates is crucial to determine appropriate management and prevent complications. Cystatin C (CysC) has been recognized as a superior kidney biomarker reflecting kidney function in neonates. The objective of this study is to evaluate the diagnostic value of CysC as an AKI biomarker in critically ill neonates. Methods: We performed a diagnostic test between cystatin C-based estimated glomerular filtration rate (eGFR-CysC) and serum creatinine-based estimated glomerular filtration rate (eGFR-SCr) as the gold standard to diagnose AKI in 135 critically ill neonates treated in Cipto Mangunkusumo National Hospital from July 2017 to January 2018. Results: Prevalence of AKI was 23.7% predominantly in neonates with a very preterm gestational age, low birthweight, probable sepsis, and those receiving invasive oxygen therapy or nephrotoxic drugs. The proportion of AKI based on neonate RIFLE criteria was 72.7% risk, 18.9% injury, and 9% failure. eGFR-CysC had the following parameters: sensitivity, 84.8%; specificity, 61.8%; PPV, 41.8%; NPV, 89.7%; LR(+), 2.2; LR(−), 0.24; and accuracy, 67.4%. The AUROC for CysC was 84.9%. The optimal cut-off value for CysC was 1.605 mg/l. Conclusions: CysC may be used as a screening biomarker of AKI in critically ill neonates; yet, it was not superior to serum creatinine. [Figure not available: see fulltext.]. © 2020, IPNA.	Acute kidney injury; Critically ill neonates; Cystatin C; Serum creatinine	creatinine; cystatin C; biological marker; creatinine; cystatin C; epidermal growth factor receptor; acute kidney failure; area under the curve; Article; controlled study; creatinine blood level; critically ill patient; diagnostic accuracy; diagnostic test; diagnostic test accuracy study; diagnostic value; estimated glomerular filtration rate; extremely low birth weight; female; gestational age; human; low birth weight; major clinical study; male; negative likelihood ratio; newborn; oxygen therapy; positive likelihood ratio; predictive value; prematurity; prevalence; priority journal; receiver operating characteristic; sensitivity and specificity; sepsis; very low birth weight; acute kidney failure; critical illness; prospective study; Acute Kidney Injury; Biomarkers; Creatinine; Critical	Springer Science and Business Media Deutschland GmbH	0931041X	32594242	Article	Q1	831	5739	View
Department of Child Health, Faculty of Medicine Universitas Indonesia, Cipto Mangunkusumo Hospital, Jl. Diponegoro No. 71, Jakarta, 10430, Indonesia; Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Department of Child Health, Faculty of Medicine Universitas Indonesia, Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Department of Pediatrics, Leiden University Medical Center, Leiden, Netherlands; Faculty of Pharmacy, Universitas Padjadjaran, Bandung, Indonesia(1)
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412	Pulungan A., Andarie A.A., Soesanti F., Yassien M.R., De Bruin C., Wijaya A., Firmansyah A., Wit J.M.	57192905981;57195935134;37068080600;57223039155;57028043300;57225459566;6602915502;7101895972;	Anthropometric, biochemical and hormonal profiles of the partially admixed pygmoid group in Rampasasa (Flores, Indonesia)	2021	Journal of Pediatric Endocrinology and Metabolism	34	5		547	557		https://www.scopus.com/inward/record.uri?eid=2-s2.0-85104614948&doi=10.1515%2fjpem-2020-0526&partnerID=40&md5=64730b2ca3a487374a34509077be3f0d	Department of Child Health, Faculty of Medicine Universitas Indonesia, Cipto Mangunkusumo Hospital, Jl. Diponegoro No. 71, Jakarta, 10430, Indonesia; Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Department of Child Health, Faculty of Medicine Universitas Indonesia, Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Department of Pediatrics, Leiden University Medical Center, Leiden, Netherlands; Faculty of Pharmacy, Universitas Padjadjaran, Bandung, Indonesia	Pulungan, A., Department of Child Health, Faculty of Medicine Universitas Indonesia, Cipto Mangunkusumo Hospital, Jl. Diponegoro No. 71, Jakarta, 10430, Indonesia; Andarie, A.A., Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Soesanti, F., Department of Child Health, Faculty of Medicine Universitas Indonesia, Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Yassien, M.R., Department of Child Health, Faculty of Medicine Universitas Indonesia, Cipto Mangunkusumo Hospital, Jakarta, Indonesia; De Bruin, C., Department of Pediatrics, Leiden University Medical Center, Leiden, Netherlands; Wijaya, A., Faculty of Pharmacy, Universitas Padjadjaran, Bandung, Indonesia; Firmansyah, A., Department of Child Health, Faculty of Medicine Universitas Indonesia, Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Wit, J.M., Department of Pediatrics, Leiden University Medical Center, Leiden, Netherlands	Objectives: We performed a cross-sectional study on anthropometric and laboratory characteristics of inhabitants of Rampasasa (Flores, Indonesia). Adults were categorised according to ancestry into three groups: pygmoid (P/P, offspring of pygmoid parents, n=8), mixed pygmoid (P/N, offspring of pygmoid and non-pygmoid parents, n=12) and non-pygmoid (N/N, n=10). Children (n=28) were P/N. Methods: Measurements included height, weight, sitting height, arm span, head circumference, haematological analysis and serum albumin, calcium, vitamin D, insulinlike growth factor-I (IGF-I) and IGF binding protein 3 (IGFBP-3). Pubertal stage and bone age was assessed in children. Anthropometric data were expressed as standard deviation score (SDS) for age. IGF-I, IGFBP-3 and IGF-I/ IGFBP-3 ratio were expressed as SDS for age, bone age and pubertal stage. Results: Mean height SDS showed a gradient from P/P (-4.0) via P/N (-3.2) to N/N (-2.3) (-3.4, -3.1 and -2.2 adjusted for age-associated shrinking). Sitting height and head circumference showed similar gradients. Serum IGF-I SDS was similar among groups (approximately -1 SDS). IGFBP-3 SDS tended toward a gradient from P/P (-1.9) via P/N (-1.5) to N/N (-1.1), but IGF-I/IGFBP-3 ratio was normal in all groups. In P/P and P/N, mean head circumference SDS was >2 SD greater than mean height SDS. Children showed a progressive growth failure and bone age delay, delayed female pubertal onset and an initial low serum IGF-I, normal IGFBP-3 and low IGF-I/IGFBP-3 ratio. Conclusions: P/P showed proportionate short stature with relative macrocephaly and relatively low IGFBP-3; P/N presented an intermediate pattern. P/N children were progressively short, showed delayed skeletal maturation, delayed puberty in girls and low IGF-I and IGF-I/IGFBP-3. © 2021 De Gruyter. All rights reserved.	Growth; Head circumference; IGF-I; IGFBP-3; Negritos; Pygmies; Short stature; Vitamin D deficiency	albumin; calcium; somatomedin binding protein 3; somatomedin C receptor; vitamin D; IGFBP3 protein, human; somatomedin binding protein 3; somatomedin C; adult; albumin blood level; analytical parameters; anthropology; anthropometry; Article; biochemistry; blood analysis; bone age; calcium blood level; child; controlled study; cross-sectional study; crossover procedure; female; head circumference; hormone determination; human; Indonesia; macrocephaly; male; molecular dynamics; population research; protein blood level; puberty; pygmy; scoring system; vitamin blood level; anthropometry; blood; body mass; body weight; bone disease; ethnic group; follow up; growth disorder; infant; metabolism; middle aged; newborn; pathology; preschool child; prognosis; Adult; Anthropometry; Body Mass Index; Bo	De Gruyter Open Ltd	0334018X	33851527	Article	Q2	502	10041	View
Department of Child Health, Faculty of Medicine Universitas Indonesia, Dr. Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Kidz Health Castle, UZ Brussel, Vrije Universiteit Brussel, Brussels, Belgium(1)
No records
116	Munadzilah S., Hegar B., Sekartini R., Vandenplas Y.	57346126700;6506273944;57224503576;57223670656;	Association between milk consumption and lactose malabsorption in Indonesian children	2021	Chinese Journal of Contemporary Pediatrics	23	10		975	980		https://www.scopus.com/inward/record.uri?eid=2-s2.0-85119440135&doi=10.7499%2fj.issn.1008-8830.2105030&partnerID=40&md5=80626db7ac7feaae0925a1057b4f77eb	Department of Child Health, Faculty of Medicine Universitas Indonesia, Dr. Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Kidz Health Castle, UZ Brussel, Vrije Universiteit Brussel, Brussels, Belgium	Munadzilah, S., Department of Child Health, Faculty of Medicine Universitas Indonesia, Dr. Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Hegar, B., Department of Child Health, Faculty of Medicine Universitas Indonesia, Dr. Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Sekartini, R., Department of Child Health, Faculty of Medicine Universitas Indonesia, Dr. Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Vandenplas, Y., Kidz Health Castle, UZ Brussel, Vrije Universiteit Brussel, Brussels, Belgium	Objective To study the association between milk consumption and lactose malabsorption in Indonesian children aged 3-12 years. Methods This cross sectional study was conducted in randomly selected presumed healthy children with good nutritional status aged 3-12 years in Central Jakarta, Indonesia (n=174), including 72 children aged 3-5 years and 102 children aged 6-12 years. Results The prevalence of lactose malabsorption in children aged 3-5 years and children aged 6-12 years was 20.8% (15/72) and 35.3% (36/102), respectively. There was no association between milk or milk product consumption and lactose malabsorption (P>0.05). In the 51 children with lactose malabsorption, the predominant clinical symptoms were diarrhea (62%), abdominal pain (52%), and nausea (5%) during the hydrogen breath test. Conclusions There is no association between milk consumption and lactose malabsorption in Indonesian children aged 3-12 years, suggesting that genetic predisposition may be more important than adaptive mechanisms to lactose consumption. © 2021 Xiangya Hospital of CSU. All rights reserved.	Child; Hydrogen breath test; Lactose malabsorption; Milk consumption; Prevalence	abdominal pain; adult; Article; child; cross-sectional study; dairy product; diarrhea; disease association; female; genetic predisposition; human; hydrogen breath test; lactose intolerance; male; milk; nausea; prevalence; animal; breath analysis; Indonesia; lactose intolerance; milk; Animals; Breath Tests; Child; Cross-Sectional Studies; Humans; Indonesia; Lactose Intolerance; Milk	Central South University	10088830	34719410	Article	Q3	174	21112	View
Department of Child Health, Faculty of Medicine, Public Health and Nursing Universitas Gadjah Mada/Dr. Sardjito General Hospital, Yogyakarta, Indonesia; Department of Child Health, Faculty of Medicine Universitas Indonesia – Cipto Mangunkusumo Hospital, Jakarta, Indonesia(1)
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782	Palupi-Baroto R., Hermawan K., Murni I.K., Nurlitasari T., Prihastuti Y., Sekali D.R.K., Ambarsari C.G.	56495463300;57224908584;55734483200;57224895124;57224909176;57224897130;57211850895;	High fibroblast growth factor 23 as a biomarker for severe cardiac impairment in children with chronic kidney disease: A single tertiary center study	2021	International Journal of Nephrology and Renovascular Disease	14			165	171	1	https://www.scopus.com/inward/record.uri?eid=2-s2.0-85108541273&doi=10.2147%2fIJNRD.S304143&partnerID=40&md5=ba9cd0eab6e18711499e83b6c4812aa7	Department of Child Health, Faculty of Medicine, Public Health and Nursing Universitas Gadjah Mada/Dr. Sardjito General Hospital, Yogyakarta, Indonesia; Department of Child Health, Faculty of Medicine Universitas Indonesia – Cipto Mangunkusumo Hospital, Jakarta, Indonesia	Palupi-Baroto, R., Department of Child Health, Faculty of Medicine, Public Health and Nursing Universitas Gadjah Mada/Dr. Sardjito General Hospital, Yogyakarta, Indonesia; Hermawan, K., Department of Child Health, Faculty of Medicine, Public Health and Nursing Universitas Gadjah Mada/Dr. Sardjito General Hospital, Yogyakarta, Indonesia; Murni, I.K., Department of Child Health, Faculty of Medicine, Public Health and Nursing Universitas Gadjah Mada/Dr. Sardjito General Hospital, Yogyakarta, Indonesia; Nurlitasari, T., Department of Child Health, Faculty of Medicine, Public Health and Nursing Universitas Gadjah Mada/Dr. Sardjito General Hospital, Yogyakarta, Indonesia; Prihastuti, Y., Department of Child Health, Faculty of Medicine, Public Health and Nursing Universitas Gadjah Mada/Dr. Sardjito General Hospital, Yogyakarta, Indonesia; Sekali, D.R.K., Department of Child Health, Faculty of Medicine Universitas Indonesia – Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Ambarsari, C.G., Department of Child Health, Faculty of Medicine Universitas Indonesia – Cipto Mangunkusumo Hospital, Jakarta, Indonesia	Introduction: Left ventricular hypertrophy (LVH) is the most common cardiac abnormality in chronic kidney disease (CKD). Changes in cardiac geometry and functions may occur in an early stage and worsen as CKD progresses. Recently, the role of fibroblast growth factor 23 (FGF23) is being highlighted and investigated in CKD-related cardiomyopathy. However, only a few studies have reviewed the utilization of FGF23 as a diagnostic biomarker in the pediatric CKD population. Purpose: This study aimed to identify the role of FGF23 as a biomarker in assessing cardiac changes in children with CKD. Patients and Methods: We conducted a cross-sectional study that involved children aged 2 to 18 years old with CKD stages 2 to 5D in Dr. Sardjito General Hospital, Yogyakarta, Indonesia. The level of FGF23 was measured using an immunometric enzyme-linked immunosorbent assay. LVMI, RWT, and left ventricular ejection fraction (LVEF) were assessed with echocardiography. Receiver-operating characteristic (ROC) analyses were conducted to assess the diagnostic performance of FGF23 in detecting LVH with impaired contractility. Results: A total of 43 children with CKD stages 2 to 5D were included, among whom the prevalence of LVH diagnosis was 95.35%. The area under the curve (AUC) of FGF23 to assess LVH and systolic dysfunction was 0.82 (95% CI 0.62–1.0), and the optimal cutoff point was 1413 RU/mL (sensitivity 80%, specificity 78.95%). The median concentration of FGF23 increased with the decreasing eGFR and the increasing LVMI although the systolic and diastolic functions were preserved. Conclusion: FGF23 might be used as an early biomarker to detect cardiac changes in pediatric CKD patients, particularly for LVH and impaired systolic function among children with CKD stage 2 and higher. © 2021 Palupi-Baroto et al.	Dialysis; End-stage kidney disease; FGF23; Left ventricular hypertrophy; Ventricular ejection fraction	biological marker; fibroblast growth factor 23; adolescent; adult; anemia; area under the curve; Article; child; chronic kidney failure; clinical article; cross-sectional study; diabetic nephropathy; diagnostic test accuracy study; diagnostic value; disease severity; echocardiography; enzyme linked immunosorbent assay; estimated glomerular filtration rate; female; glomerulonephritis; heart left ventricle contractility; heart left ventricle contraction; heart left ventricle ejection fraction; heart left ventricle filling; heart left ventricle mass; heart ventricle hypertrophy; human; hypertension; Indonesia; kidney agenesis; kidney calcification; kidney dysplasia; kidney hypoplasia; lupus erythematosus nephritis; male; nephrotic syndrome; obstructive uropathy; preschool child; prevalence; r	Dove Medical Press Ltd	11787058		Article	Q2	846	5589	View
Department of Child Health, Faculty of Medicine, Universitas Indonesia – Dr Cipto Mangunkusumo General Hospital, Jakarta, Indonesia; Harapan Kita National Center for Woman and Child Health Care, Jakarta, Indonesia(1)
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723	Rohsiswatmo R., Widodo A.D., Munasir Z., Medise B.E.	55533574600;57117722400;7801694370;57226215370;	Prebiotic supplementation supports immunity & growth-development in preterm infants: A review and expert perspectives	2021	Bali Medical Journal	10	2		785	792		https://www.scopus.com/inward/record.uri?eid=2-s2.0-85114340415&doi=10.15562%2fbmj.v10i2.2490&partnerID=40&md5=cffe54e9756788dc9eeb8ca22d1e3c5a	Department of Child Health, Faculty of Medicine, Universitas Indonesia – Dr Cipto Mangunkusumo General Hospital, Jakarta, Indonesia; Harapan Kita National Center for Woman and Child Health Care, Jakarta, Indonesia	Rohsiswatmo, R., Department of Child Health, Faculty of Medicine, Universitas Indonesia – Dr Cipto Mangunkusumo General Hospital, Jakarta, Indonesia; Widodo, A.D., Harapan Kita National Center for Woman and Child Health Care, Jakarta, Indonesia; Munasir, Z., Department of Child Health, Faculty of Medicine, Universitas Indonesia – Dr Cipto Mangunkusumo General Hospital, Jakarta, Indonesia; Medise, B.E., Department of Child Health, Faculty of Medicine, Universitas Indonesia – Dr Cipto Mangunkusumo General Hospital, Jakarta, Indonesia	Preterm birth still causes significant mortality and morbidity in newborns, despite modern advancements in preterm care. The gut microbiota is the most significant microbial colonization in the human body and plays a significant role in supporting a healthy body. Preterm infants are susceptible to gut dysbiosis, which is thought to contribute to the many adverse outcomes of prematurity, such as necrotizing enterocolitis (NEC), late-onset sepsis (LOS), and developmental delays. Human breast milk is considered the ideal nutrition source for newborns and can help create ideal microbiota in preterm infants. Breast milk contains human milk oligosaccharides (HMO), prebiotics that promote beneficial bacteria growth, absent in cow’s milk. Supplementation of non-milk oligosaccharides such as long-chain fructo-oligosaccharides (lcFOS) and small-chain galacto-oligosaccharides (scGOS) in formula milk for preterm infants is found to be beneficial with a favourable safety profile. This review discusses gut microbiota in preterm neonates, its role in developing immune systems, growth and development, and the benefits of prebiotic supplementation. © 2021, Sanglah General Hospital. All rights reserved.	Development; Growth; Immunity; Prebiotic; Prematurity; Preterm birth		Sanglah General Hospital	20891180		Review	#N/A	#N/A	#N/A	View

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