|
No records
|
|
536 |
Tua Lubis A.M., Budimansyah M., Made Febry Siswanto I.G., Yanuarso Y., Marsetio A.F. |
15122639800;57222168054;57222170597;57222173063;57192180884; |
Functional outcome of implant-free bone-patellar tendon autograft versus hamstring autograft in arthroscopic anterior cruciate ligament reconstruction: A prospective study |
2021 |
Annals of Medicine and Surgery |
63 |
|
102184 |
|
|
|
|
https://www.scopus.com/inward/record.uri?eid=2-s2.0-85101786286&doi=10.1016%2fj.amsu.2021.102184&partnerID=40&md5=2c7a67ad1a6831d518d84971baadc9be |
Universitas Indonesia-Cipto Mangunkusumo General Hospital, Jl. Diponegoro No. 71, Jakarta, Pusat 10430, Indonesia; Persahabatan Hospital, Jl. Persahabatan Raya No.1, Jakarta, Timur 13230, Indonesia; Royal Progress Hospital, Jl. Danau Sunter Utara, Tanjung Priok, Jakarta, Utara 14350, Indonesia; Gatot Soebroto Army Hospital, Jl. Abdul Rahman Saleh Raya No.24, Senen, Jakarta, Pusat 10410, Indonesia |
Tua Lubis, A.M., Universitas Indonesia-Cipto Mangunkusumo General Hospital, Jl. Diponegoro No. 71, Jakarta, Pusat 10430, Indonesia; Budimansyah, M., Persahabatan Hospital, Jl. Persahabatan Raya No.1, Jakarta, Timur 13230, Indonesia; Made Febry Siswanto, I.G., Royal Progress Hospital, Jl. Danau Sunter Utara, Tanjung Priok, Jakarta, Utara 14350, Indonesia; Yanuarso, Y., Gatot Soebroto Army Hospital, Jl. Abdul Rahman Saleh Raya No.24, Senen, Jakarta, Pusat 10410, Indonesia; Marsetio, A.F., Universitas Indonesia-Cipto Mangunkusumo General Hospital, Jl. Diponegoro No. 71, Jakarta, Pusat 10430, Indonesia |
Introduction: The use of implant in anterior cruciate ligament (ACL) reconstruction has been associated with several drawbacks including graft injury, implant osteolysis, implant migration and soft tissue irritation. Implant-free ACL reconstruction surgery offers additional benefits of cost-effective, improved graft incorporation and ease of revision surgery. Our study aimed to compare the functional outcome of ACL reconstruction by using bone-patellar tendon autograft with press-fit fixation technique and hamstring autografts with implant. Methods: A prospective cohort study design was used. Between March 2013 and March 2014, 12 patients underwent patella tendon-bone graft fixated by press-fit fixation technique (implant-free), while 24 patients underwent ACL reconstruction using implant-fixated hamstring tendon graft. Objective functional outcome was measured by using rolimeter, and subjective functional outcome was measured according to the functional score of IKDC, Tegner-Lysholm and KOOS. Results: Both techniques have shown no significant difference in terms of functional outcome, whether assessed by rolimeter measurement, IKDC score, Tegner-Lysholm, KOOS score between implant group and implant-free group, preoperatively and postoperatively. Discussion: Our study results are in line with several other studies with various follow-up time and systematic review. With the right technique, graft harvesting of patella tendon-tibial tuberosity bone block can be successfully performed, and associated donor site morbidity can be avoided. Conclusion: Patients who underwent ACL reconstruction using implant-free technique by press-fit fixation had comparable outcome with ACL reconstruction with implant, objectively and subjectively. This technique should be further revisited and reevaluated. © 2021 The Authors |
Anterior cruciate ligament; Anterior cruciate ligament injury; Bone-patellar tendon; Implant-free ACL reconstruction; Press-fit fixation |
adult; anterior cruciate ligament reconstruction; arthroscopic surgery; Article; bone patellar tendon bone graft; cohort analysis; controlled study; female; follow up; graft harvesting; hamstring tendon; human; Knee Injury and Osteoarthritis Outcome Score; male; nuclear magnetic resonance imaging; press fit graft fixation technique; prospective study; randomized controlled trial; scoring system; soccer; Tegner activity score; Tegner-Lysholm Knee Scoring Scale; tibial tuberosity; traffic accident; volleyball |
Elsevier Ltd |
20490801 |
|
|
Article |
Q3 |
391 |
12334 |
|
|
|
538 |
Seswandhana R., Makrufardi F., Sudjatmiko G. |
8718699600;57214993245;16025731000; |
Fistula incidence after primary repair and correlation with cleft width-to-palatum width ratio: A prospective cohort study |
2021 |
Annals of Medicine and Surgery |
63 |
|
102183 |
|
|
|
|
https://www.scopus.com/inward/record.uri?eid=2-s2.0-85101659670&doi=10.1016%2fj.amsu.2021.102183&partnerID=40&md5=ad5a9021a2b2389751b7ee5f65e256ee |
Plastic, Reconstructive, and Aesthetic Surgery Division, Department of Surgery, Faculty of Medicine, Public Health and Nursing, Universitas Gadjah Mada/Dr. Sardjito Hospital, Yogyakarta, 55281, Indonesia; Department of Plastic Reconstructive, and Aesthetic Surgery, Faculty of Medicine, Universitas Indonesia/Dr. Cipto Mangunkusumo Hospital, Jakarta, Indonesia |
Seswandhana, R., Plastic, Reconstructive, and Aesthetic Surgery Division, Department of Surgery, Faculty of Medicine, Public Health and Nursing, Universitas Gadjah Mada/Dr. Sardjito Hospital, Yogyakarta, 55281, Indonesia; Makrufardi, F., Plastic, Reconstructive, and Aesthetic Surgery Division, Department of Surgery, Faculty of Medicine, Public Health and Nursing, Universitas Gadjah Mada/Dr. Sardjito Hospital, Yogyakarta, 55281, Indonesia; Sudjatmiko, G., Department of Plastic Reconstructive, and Aesthetic Surgery, Faculty of Medicine, Universitas Indonesia/Dr. Cipto Mangunkusumo Hospital, Jakarta, Indonesia |
Background: Cleft lip with or without cleft palate is one of the most common birth defects and is certainly the most visible. Fistula rate after primary palatoplasty was ranging between 10 and 23% and could be detected in the first three weeks after surgery. The cleft width is the frequent factor which was assumed to correspond to fistula occurrence. This study aimed to find correlation between fistula occurrence with cleft width and palatum width ratio after primary palate repair. Methods: A prospective cohort study was conducted on 16 subjects, which consisted of 10 males and 6 females. We measured width of cleft palate, width of rest palate and width of palate arch on three level measurements (posterior, junction and anterior). The surgery was performed using the two-flap and three layers suturing technique. Results: Sixteen patients were enrolled in this study during January and February 2008. Ten patients were diagnosed with unilateral cleft palate while six patients had bilateral cleft palate. Mean of age was 22.31 ± 5.86 month. Correlation analysis between fistula occurrence and cleft width, cleft width-remnant palate width ratio and cleft width-palate arch width ratio using logistic regression did not show statistical correlation, and the same result was found between fistula occurrence and hemoglobin level, white blood count, nutritional status, cleft type and caries dentis factors (p > 0.05). Conclusion: Width of the cleft is not a factor associated with fistula occurrence. Two-flap three layers technique could be considered as a simple technique and gives a low rate of fistula occurrence. © 2021 |
Cleft width and palate width ratio; Fistula occurrence; Primary palatoplasty; Two-flap three layers suturing technique |
amoxicillin; epinephrine; hemoglobin; lidocaine; paracetamol; anemia; anthropometry; Article; blood cell count; child; cleft palate; clinical article; cohort analysis; controlled study; correlation analysis; dental caries; female; fistula; gestational age; hemoglobin blood level; human; leukocyte count; major clinical study; male; nutritional status; obesity; palatoplasty; primary palate; prospective study; protein expression; suture technique |
Elsevier Ltd |
20490801 |
|
|
Article |
Q3 |
391 |
12334 |
|
|
|
544 |
Dilogo I.H., Prabowo I. |
56161962800;57221098612; |
The role of angioembolization and C-clamp fixation: Damaged control orthopaedic in haemodynamically unstable pelvic fracture |
2021 |
Annals of Medicine and Surgery |
63 |
|
102157 |
|
|
|
|
https://www.scopus.com/inward/record.uri?eid=2-s2.0-85101301928&doi=10.1016%2fj.amsu.2021.02.003&partnerID=40&md5=67b060a519b64a2c9d49653397546350 |
Department of Orthopaedic and Traumatology, Faculty of Medicine Universitas Indonesia, Dr Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Resident of Department of Orthopaedic and Traumatology, Faculty of Medicine Universitas Indonesia, Dr Cipto Mangunkusumo Hospital, Jakarta, Indonesia |
Dilogo, I.H., Department of Orthopaedic and Traumatology, Faculty of Medicine Universitas Indonesia, Dr Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Prabowo, I., Resident of Department of Orthopaedic and Traumatology, Faculty of Medicine Universitas Indonesia, Dr Cipto Mangunkusumo Hospital, Jakarta, Indonesia |
Introduction: Unstable pelvic fracture may emerge to major bleeding complication. Angioembolization is one of method to stop the bleeding effectively. This case series aims to analyze whether the bleeding of unstable pelvic fracture is managed by angioembolization to achieve the better functional outcome. Presentation of case: Three cases of haemodynamically unstable pelvic fracture were studied retrospectively and prospectively. A staged approach using damage control orthopaedic surgery was performed. Initial resuscitation began from fluid resuscitation, pelvic wrapping using binder. All patients followed with pelvic external fixation, while 2 patients immediately replaced binder to C-Clamp, and 1 patient with anterior frame. Angioembolization was done to all patients. All patients required definitive internal fixation, while only 2 patients reach the definitive surgery. Finally, we measured the functional outcome of all patients using Hannover Pelvic score, Majeed pelvic score, and Iowa Pelvic score. Discussion: We review some literatures regarding pelvic angioembolization. The previous study suggested to resuscitate patients when the hemodynamic is unstable, the angioembolization procedure is still preferred. The indication and successful definition of this procedure is still unclear, yet it shows decrease of mortality rate of pelvic injury if this procedure starts ahead a schedule. Conclusion: Angioembolization as a part of damaged control orthopaedic has been shown a favorable result in managing unstable pelvic injury. © 2021 The Authors |
Angiographic embolization; Pelvic fracture; Pelvic injury |
D dimer; fibrinogen; adult; Article; artificial embolization; blood cell count; body temperature; breathing rate; case report; clinical article; female; fluid resuscitation; fracture; fracture external fixation; fracture fixation; Glasgow coma scale; heart rate; hemodynamics; hospitalization; human; lactate blood level; male; multiple trauma; orthopedics; pelvis fracture; resuscitation; systolic blood pressure; treatment response |
Elsevier Ltd |
20490801 |
|
|
Article |
Q3 |
391 |
12334 |
|
|
|
545 |
Librianto D., Saputra R., Djaja Y.P., Phedy P., Fachrisal, Saleh I. |
57192894799;57222027710;57191042059;57190427771;57210265362;57191511801; |
Preoperative skull tongs-femoral traction versus cotrel longitudinal traction for rigid and severe scoliosis: Cohort study |
2021 |
Annals of Medicine and Surgery |
63 |
|
102177 |
|
|
|
1 |
https://www.scopus.com/inward/record.uri?eid=2-s2.0-85101045625&doi=10.1016%2fj.amsu.2021.02.023&partnerID=40&md5=3832baf23c70f5495e6f6c6880d960fa |
Department of Orthopedic & Traumatology, Fatmawati General Hospital, Jakarta, Indonesia; Department of Orthopaedic & Traumatology, Cipto Mangunkusumo General Hospital, Faculty of Medicine Universitas Indonesia, Jakarta, Indonesia |
Librianto, D., Department of Orthopedic & Traumatology, Fatmawati General Hospital, Jakarta, Indonesia; Saputra, R., Department of Orthopaedic & Traumatology, Cipto Mangunkusumo General Hospital, Faculty of Medicine Universitas Indonesia, Jakarta, Indonesia; Djaja, Y.P., Department of Orthopedic & Traumatology, Fatmawati General Hospital, Jakarta, Indonesia; Phedy, P., Department of Orthopedic & Traumatology, Fatmawati General Hospital, Jakarta, Indonesia; Fachrisal, Department of Orthopedic & Traumatology, Fatmawati General Hospital, Jakarta, Indonesia; Saleh, I., Department of Orthopaedic & Traumatology, Cipto Mangunkusumo General Hospital, Faculty of Medicine Universitas Indonesia, Jakarta, Indonesia |
Background: To compare two methods of preoperative traction (Cotrel traction exercises and skull tongs femoral traction) in severe scoliosis treatment. Methods: We collected retrospective data of severe (>80°) and rigid scoliosis patients who underwent preoperative traction before correction surgery from 2016 to 2018. The first group consisted of patients who underwent Cotrel traction exercises and second group underwent continuous-progressively increasing Skull Tongs Femoral Traction (STFT) traction. Posterior fusion was performed in all patients. Intraoperative parameters (blood loss, operation time and level instrumented) and radiologic change (initial, post-traction and postoperative Cobb Angle) was evaluated and analyzed. Results: Thirty consecutive case of severe and rigid scoliosis were included (15 in each group). Despite Cotrel group having larger initial Cobb angle, the amount of post traction correction was statistically similar in both groups (16.4° and 11.8°, in STFT and Cotrel group respectively). Mean traction duration was 14.0 days for Cotrel group and 12 days for STFT. There were also no significant differences in postoperative curve correction rate between two groups, although STFT group had a slightly higher correction rate (69.3° vs 55.0°). No major/neurologic complication were found in our series. Conclusions: Both preoperative traction methods were found safe and beneficial to reduce preoperative curve degree before definitive scoliosis correction surgery. Although, no statistical difference were found between two methods, STFT may provide better correction rate. Level of evidence: 3. © 2021 |
Cotrel traction; Preoperative traction; Scoliosis; Severe scoliosis; Skull tong femoral traction |
adolescent; adult; Article; body mass; case report; child; clinical article; clinical trial; Cobb angle; cohort analysis; comparative study; cotrel longitudinal traction; exercise; female; flexibility index; follow up; human; major compensatory coronal curve magnitude; major coronal curve magnitude; major sagittal curve magnitude; male; operation duration; operative blood loss; osteomyelitis; physical parameters; retrospective study; scoliosis; skull tongs femoral traction; spine radiography; traction therapy; young adult |
Elsevier Ltd |
20490801 |
|
|
Article |
Q3 |
391 |
12334 |
|
|
|
580 |
Tobing S.D.A., Fachrisal, Junaidi M.A. |
57192893142;57210265362;57218416973; |
Clinical and radiological outcome analysis among patients with spondylitis tuberculosis of the lumbar vertebrae after correction and posterior instrumentation in cipto mangunkusumo and Fatmawati Hospital in 2018–2020: A cross sectional study |
2021 |
Annals of Medicine and Surgery |
62 |
|
|
463 |
468 |
|
|
https://www.scopus.com/inward/record.uri?eid=2-s2.0-85100317183&doi=10.1016%2fj.amsu.2021.01.074&partnerID=40&md5=22fe0ba7d0e6ced7481d5f851558d39b |
Department of Orthopaedics and Traumatology, Faculty of Medicine-Universitas Indonesia, Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Department of Orthopaedics and Traumatology, Fatmawati General Hospital, Jakarta, Indonesia |
Tobing, S.D.A., Department of Orthopaedics and Traumatology, Faculty of Medicine-Universitas Indonesia, Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Fachrisal, Department of Orthopaedics and Traumatology, Fatmawati General Hospital, Jakarta, Indonesia; Junaidi, M.A., Department of Orthopaedics and Traumatology, Faculty of Medicine-Universitas Indonesia, Cipto Mangunkusumo Hospital, Jakarta, Indonesia |
Introduction: Spondylitis tuberculosis can cause changes in spinopelvic parameters including pelvic incidence, pelvic tilt, and sacral slope due to biomechanical changes of the spine. Posterior instrumentation is one of the modality for the treatment of spondylitis tuberculosis. However, in Indonesia, clinical and radiological outcomes after posterior instrumentation in tuberculosis of lumbar vertebrae are still rare. This study aims to investigate the clinical and radiological outcomes of patients with spondylitis tuberculosis of the lumbar vertebrae after posterior instrumentation. Method: This study was a cross-sectional study in patients with spondylitis tuberculosis of the lumbar vertebrae who underwent posterior instrumentation in Cipto Mangunsukumo and Fatmawati Hospital. Subjects were collected through consecutive sampling. 23 subjects were collected and analyzed. Clinical and radiological outcomes before and after posterior instrumentation were compared. The clinical outcome included the Visual Analog Scale (VAS) and Oswestry Disability Index (ODI). The radiological outcome included sacral slope, pelvic tilt, pelvic incidence, and lumbar lordosis. Results: The median age of the subjects was 31 (9–57) years with a female-majority (60,9%). The median of the total vertebral infected was 2 (1–4). Median of VAS score before surgery, 6 months after surgery, and 12 months after surgery were 9 (4–10), 4 (1–7), dan 2 (1–6) (p < 0,001) consecutively. Median of ODI score before surgery, 6 months after surgery, and 12 months after surgery were 70 (40–86), 34 (10–74), dan 12 (2–74) (p < 0,001) consecutively. There was no significant difference in spinopelvic parameters before and after the surgery. The difference of ODI score before and after the surgery inversely correlated with the difference of lumbar lordotic and sacral slope. Conclusion: Posterior instrumentation could improve clinical outcomes in patients with spondylitis tuberculosis of the lumbar. Change of lumbar lordotic and sacral slope after posterior instrumentation led to an improvement of quality of life marked by the reduction of the ODI score. © 2021 The Authors |
ODI; Posterior instrumentation; Spinopelvic parameter; Spondylitis tuberculosis; VAS |
|
Elsevier Ltd |
20490801 |
|
|
Article |
Q3 |
391 |
12334 |
|
|
|
586 |
Lalisang T.J.M., Situmorang I., Ibrahim F., Widianto P., Marbun V.M.G. |
36623976300;57192894939;57215488702;57221641291;57211643232; |
Management of post-cholecystectomy bile duct injuries without operative mortality at Jakarta tertiary hospital in Indonesia – A cross-sectional study |
2021 |
Annals of Medicine and Surgery |
62 |
|
|
211 |
215 |
|
|
https://www.scopus.com/inward/record.uri?eid=2-s2.0-85099686135&doi=10.1016%2fj.amsu.2021.01.012&partnerID=40&md5=4f1cef507559e65d3a6a5f5f83b7a17c |
Digestive Surgery Division, Faculty of Medicine Universitas Indonesia, Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Surgery Department, Pelni Hospital, Jakarta, Indonesia; Surgery Department, Persahabatan Hospital, Jakarta, Indonesia |
Lalisang, T.J.M., Digestive Surgery Division, Faculty of Medicine Universitas Indonesia, Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Situmorang, I., Surgery Department, Pelni Hospital, Jakarta, Indonesia; Ibrahim, F., Digestive Surgery Division, Faculty of Medicine Universitas Indonesia, Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Widianto, P., Surgery Department, Persahabatan Hospital, Jakarta, Indonesia; Marbun, V.M.G., Digestive Surgery Division, Faculty of Medicine Universitas Indonesia, Cipto Mangunkusumo Hospital, Jakarta, Indonesia |
Background: Bile duct injuries (BDI) can occur after a cholecystectomy procedure performed by any surgeons. These ensured a poor experience for patients and surgeons and marred the minimally invasive surgery approach, which should have promised rapid recovery. This study aimed to evaluate the management of BDI following cholecystectomy procedure in Cipto Mangunkusumo Hospital, Jakarta, as a tertiary hospital. Method: Descriptive retrospective cross-sectional design was used on open and laparoscopic cholecystectomy performed between January 2008 and December 2018. This study is reported in line with STROCSS 2019 Criteria. Result: A total of 24 patients with BDI were included, with female preponderance (62,5%) with a median age 45 (21–58) years. Sixteen post-laparoscopy cases were classified according to Strasberg classification; 6 cases were type E3, 2 cases each of type E1 and E2, and one case each of Strasberg C and D. The remaining 4 were Strasberg A. Eight post-open cases were classified based on Bismuth criteria: 4 cases of Bismuth I, 1 case of Bismuth II, and 3 cases of Bismuth III. Five cases were presented with massive biloma, 7 with jaundice, and 10 cases with biliary-pancreatic fluid production through the surgical drain. The average time of problem recognition to patient's admission was 19 (7–152) days and admission to surgery was 14 days. Roux-en-Y hepaticojejunostomy was performed in 18 cases, choledocho-duodenostomy in 2 cases, and primary ligation cystic duct in 4 cases. Post-operative follow-up showed 2 patients had recurrent cholangitis, 2 superficial surgical site infection, and 2 relaparotomy due to bile anastomosis leakage and burst abdomen. The median length of hospital stay was 38 (14–53) days with zero hospital mortality. No stricture detected in long term follow-up. Conclusion: Common bile duct was the most frequent site of BDI, and Roux-en-Y hepaticojejunostomy reconstruction performed by HPB surgeons on high volume center results in a good outcome. © 2021 The Authors |
Bile duct injury; Cholecystectomy; Roux-en-Y-Hepaticojejunostomy |
abscess; adult; Article; bile duct injury; biloma; cholangitis; cholecystectomy; choledochoduodenostomy; clinical article; cross-sectional study; endoscopic retrograde cholangiopancreatography; female; hepatojejunostomy; hospitalization; human; jaundice; laparoscopic surgery; laparotomy; length of stay; malnutrition; middle aged; percutaneous transhepatic cholangiography; retrospective study; Roux-en-Y gastric bypass; surgical infection; ultrasound |
Elsevier Ltd |
20490801 |
|
|
Article |
Q3 |
391 |
12334 |
|
|
|
911 |
Kurniawan A., Kodrat E., Gani Y.I. |
57204398223;57191430080;57195936648; |
Effectiveness of granulocyte colony stimulating factor to enhance healing on delayed union fracture model Sprague-Dawley rat |
2021 |
Annals of Medicine and Surgery |
61 |
|
|
54 |
60 |
|
1 |
https://www.scopus.com/inward/record.uri?eid=2-s2.0-85098139356&doi=10.1016%2fj.amsu.2020.12.005&partnerID=40&md5=55751366daec87d69d3f9b7fe9113d43 |
Paediatric Orthopaedic Division, Department of Orthopaedics and Traumatology, Faculty of Medicine Universitas Indonesia-Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Musculoskletal Pathology Division, Departement of Anatomic Phatology, Faculty of Medicine Universitas Indonesia-Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Orthopaedics and Traumatology, Faculty of Medicine, Universitas Indonesia-Cipto Mangunkusumo Hospital, Jakarta, Indonesia |
Kurniawan, A., Paediatric Orthopaedic Division, Department of Orthopaedics and Traumatology, Faculty of Medicine Universitas Indonesia-Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Kodrat, E., Musculoskletal Pathology Division, Departement of Anatomic Phatology, Faculty of Medicine Universitas Indonesia-Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Gani, Y.I., Orthopaedics and Traumatology, Faculty of Medicine, Universitas Indonesia-Cipto Mangunkusumo Hospital, Jakarta, Indonesia |
Introduction: Delayed union is a problem that can occur after fracture healing. Many studies were conducted based on the diamond concept approach to solve the problem of delayed union. Granulocyte-colony stimulating factor (G-CSF) is one of the various substances known to have a positive role in healing skeletal tissue or adjuvant regeneration. This study was conducted to see the effect of G-CSF in affecting delayed union fracture healing. Materials and method: The experimental study was conducted by randomized posttest only control group design on 24 experimental animals Sprague-Dawley white rats that had experienced delayed union models. The study compared the treatment group injected with subcutaneous G-CSF with a control group and was divided into four groups (n = 6). Harvest and follow-up histomorphometry and immunohistochemistry were performed in the second week and in the fourth week the histomorphometry analysis consisted of the percentage of immature bone area, cartilage, and fibrous area. The semiquantitative evaluation of immunohistochemistry with the expression of BMP-2 through the immunoreactive score (IRS). Result: In the evaluation of histomorphometry and immunohistochemical parameters, there were significantly more woven bone area (p = 0,015), less fibrosis area (p = 0,002) and higher BMP 2 expression (p = 0,004) in treatment group week four compared to control. . Conclusion: G-CSF was shown to increase the speed of healing in Sprague-Dawley rats on delayed union models evaluated from histomorphometry and immunohistochemical aspects. © 2020 The Author(s) |
BMP-2; Delayed union; Fracture healing; Granulocyte-colony stimulating factor; Histomorphometry; Immunohistochemistry |
bone morphogenetic protein 2; CD146 antigen; granulocyte colony stimulating factor; phenobarbital; animal experiment; animal model; animal tissue; Article; cartilage; comparative study; controlled study; fibrosis; follow up; fracture healing; histopathology; immunohistochemistry; immunoreactivity; male; morphometry; nonhuman; osteoblast; osteocyte; osteotomy; outcome assessment; protein expression; quantitative analysis; rat; surgical wound |
Elsevier Ltd |
20490801 |
|
|
Article |
Q3 |
391 |
12334 |
|
|
|
No records
|
|
871 |
Turana Y., Widyantoro B., Situmorang T.D., Delliana J., Roesli R.M.A., Danny S.S., Suhardjono, Sofiatin Y., Hermiawaty E., Kuncoro A.S., Barack R., Beaney T., Ster A.C., Poulter N.R., Santoso A. |
56083326000;35286148600;57202120316;57208720930;26428909500;56221848700;57205723084;56815068100;57208721982;56008103000;57202111674;55614780900;57221978746;7006154423;36905206100; |
May measurement Month 2018: An analysis of blood pressure screening results from Indonesia |
2021 |
European Heart Journal, Supplement |
22 |
|
|
H66 |
H69 |
|
2 |
https://www.scopus.com/inward/record.uri?eid=2-s2.0-85101322980&doi=10.1093%2fEURHEARTJ%2fSUAA031&partnerID=40&md5=16a05b90991c40fdd180dd4e051eaaad |
Department of Neurology, School of Medicine and Health Science, Atma Jaya Catholic University of Indonesia, Jakarta, 14440, Indonesia; Department of Cardiology - Vascular Medicine, Faculty of Medicine, Universitas Indonesia, National Cardiovascular Center, Harapan Kita Hospital, Jl. S. Parman Kav 87, Slipi, Jakarta, 11420, Indonesia; Division of Nephrology, Department of Internal Medicine, PGI Cikini Hospital, Jakarta, 10330, Indonesia; Department of Cardiology, Directorate of Non-Communicable Disease, Ministry of Health - Republic of Indonesia, Jalan Percetakan Negara 29, Jakarta, 10560, Indonesia; Department of Internal Medicine, Faculty of Medicine, Padjadjaran University, Hasan Sadikin General Hospital, Bandung, 40161, Indonesia; Division of Nephrology and Hypertension, Department of Internal Medicine, Faculty of Medicine, Universitas Indonesia-Cipto, Mangunkusumo National General Hospital, Jalan Pangeran Diponegoro No: 71, Jakarta, 10430, Indonesia; Department of Public Health, Faculty of Medicine, Padjadjaran University, Jalan Prof. Eijkman 38, Bandung, 40161, Indonesia; Department of Neurology, National Cardiovascular Center, Harapan Kita Hospital, Jl. S. Parman Kav 87, Slipi, Jakarta, 11420, Indonesia; Department of Cardiology, MMC Hospital, Jakarta, Indonesia; Imperial Clinical Trials Unit, Imperial College London, Stadium House, 68 Wood Lane, Shepherd's Bush, London, W12 7RH, United Kingdom; Department of Primary Care and Public Health, Imperial College London, St Dunstan's Road, London, W6 8RP, United Kingdom |
Turana, Y., Department of Neurology, School of Medicine and Health Science, Atma Jaya Catholic University of Indonesia, Jakarta, 14440, Indonesia; Widyantoro, B., Department of Cardiology - Vascular Medicine, Faculty of Medicine, Universitas Indonesia, National Cardiovascular Center, Harapan Kita Hospital, Jl. S. Parman Kav 87, Slipi, Jakarta, 11420, Indonesia; Situmorang, T.D., Division of Nephrology, Department of Internal Medicine, PGI Cikini Hospital, Jakarta, 10330, Indonesia; Delliana, J., Department of Cardiology, Directorate of Non-Communicable Disease, Ministry of Health - Republic of Indonesia, Jalan Percetakan Negara 29, Jakarta, 10560, Indonesia; Roesli, R.M.A., Department of Internal Medicine, Faculty of Medicine, Padjadjaran University, Hasan Sadikin General Hospital, Bandung, 40161, Indonesia; Danny, S.S., Department of Cardiology - Vascular Medicine, Faculty of Medicine, Universitas Indonesia, National Cardiovascular Center, Harapan Kita Hospital, Jl. S. Parman Kav 87, Slipi, Jakarta, 11420, Indonesia; Suhardjono, Division of Nephrology and Hypertension, Department of Internal Medicine, Faculty of Medicine, Universitas Indonesia-Cipto, Mangunkusumo National General Hospital, Jalan Pangeran Diponegoro No: 71, Jakarta, 10430, Indonesia; Sofiatin, Y., Department of Public Health, Faculty of Medicine, Padjadjaran University, Jalan Prof. Eijkman 38, Bandung, 40161, Indonesia; Hermiawaty, E., Department of Neurology, National Cardiovascular Center, Harapan Kita Hospital, Jl. S. Parman Kav 87, Slipi, Jakarta, 11420, Indonesia; Kuncoro, A.S., Department of Cardiology - Vascular Medicine, Faculty of Medicine, Universitas Indonesia, National Cardiovascular Center, Harapan Kita Hospital, Jl. S. Parman Kav 87, Slipi, Jakarta, 11420, Indonesia; Barack, R., Department of Cardiology, MMC Hospital, Jakarta, Indonesia; Beaney, T., Imperial Clinical Trials Unit, Imperial College London, Stadium House, 68 Wood Lane, Shepherd's Bush, London, W12 7RH, United Kingdom, Department of Primary Care and Public Health, Imperial College London, St Dunstan's Road, London, W6 8RP, United Kingdom; Ster, A.C., Imperial Clinical Trials Unit, Imperial College London, Stadium House, 68 Wood Lane, Shepherd's Bush, London, W12 7RH, United Kingdom; Poulter, N.R., Imperial Clinical Trials Unit, Imperial College London, Stadium House, 68 Wood Lane, Shepherd's Bush, London, W12 7RH, United Kingdom; Santoso, A., Department of Cardiology - Vascular Medicine, Faculty of Medicine, Universitas Indonesia, National Cardiovascular Center, Harapan Kita Hospital, Jl. S. Parman Kav 87, Slipi, Jakarta, 11420, Indonesia |
Elevated blood pressure (BP) is a significant burden worldwide, leading to high cardiocerebro-reno-vascular morbidity and mortality. For the second year of the May Measurement Month (MMM) campaign in Indonesia in 2018, we recruited 174 sites in 31 out of 34 provinces in Indonesia and screened through convenience sampling in public areas and rural primary health centres. Hypertension was defined as systolic BP ≥140 mmHg or diastolic BP ≥90 mmHg, or both, or on the basis of receiving antihypertensive medication. Blood pressure was measured three times followed the standard global MMM protocol, multiple imputation was used to estimate the mean of the 2nd and 3rd BP readings if these were not recorded. A total of 91 222 individuals were screened, and after multiple imputations, 27 331 (30.0%) had hypertension. Of individuals not receiving antihypertensive medication, 14 367 (18.4%) were hypertensive. Among the 47.4% of hypertensive individuals on antihypertensive medication, 10 106 (78.0%) had uncontrolled BP. MMM17 and MMM18 were still the most extensive standardized screening campaigns for BP measurement in Indonesia. Compared to the previous study, the proportion with uncontrolled BP on medication was significantly higher and provided the substantial challenges in managing hypertension in the rural community. © The Author(s) 2020. |
Blood pressure; Community; Control; Hypertension; Screening |
antihypertensive agent; adult; antihypertensive therapy; Article; blood pressure measurement; controlled study; cross-sectional study; female; human; hypertension; hypertensive patient; Indonesia; major clinical study; male; primary health care; priority journal; rural population |
Oxford University Press |
1520765X |
|
|
Article |
Q3 |
389 |
12388 |
|
|
