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Meilia P.D.I., Herkutanto, Atmadja D.S., Cordner S., Eriksson A., Kubat B., Kumar A., Payne-James J.J., Rubanzana W.G., Uhrenholt L., Freeman M.D., Zeegers M.P. |
57204065074;57204069374;6507824506;7005870991;7202802446;6602085186;57202849040;7005419201;56514032500;14061357600;34769701500;7003691618; |
The PERFORM-P (Principles of Evidence-based Reporting in FORensic Medicine-Pathology version) |
2021 |
Forensic Science International |
327 |
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110962 |
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https://www.scopus.com/inward/record.uri?eid=2-s2.0-85114050611&doi=10.1016%2fj.forsciint.2021.110962&partnerID=40&md5=2f9ffc7c51b3342895994d7c7de9fde4 |
Care and Public Health Research Institute (CAPHRI), Maastricht University Medical Center+, Maastricht, Netherlands; Department of Forensic Medicine and Medicolegal Studies, Faculty of Medicine, University of Indonesia, Jakarta, Indonesia; The Victorian Institute of Forensic Medicine, Melbourne, Victoria, Australia; Dept of Community Medicine and Rehabilitation/Forensic Medicine, Umeå University, Umeå, Sweden; Faculty of Health, Medicine and Life Science, Maastricht University, Maastricht, Netherlands; Forensic Medicine and Toxicology, All India Institute of Medical SciencesNew Delhi, India; William Harvey Research Institute, Queen Mary University of London, London, UK, United Kingdom; Department of Epidemiology and Biostatistics, University of Rwanda College of Medicine and Health Sciences, School of Public Health, Kigali, Rwanda; Department of Forensic Medicine, Section of Forensic Pathology, Aarhus University, Aarhus, Denmark |
Meilia, P.D.I., Care and Public Health Research Institute (CAPHRI), Maastricht University Medical Center+, Maastricht, Netherlands; Herkutanto, Department of Forensic Medicine and Medicolegal Studies, Faculty of Medicine, University of Indonesia, Jakarta, Indonesia; Atmadja, D.S., Department of Forensic Medicine and Medicolegal Studies, Faculty of Medicine, University of Indonesia, Jakarta, Indonesia; Cordner, S., The Victorian Institute of Forensic Medicine, Melbourne, Victoria, Australia; Eriksson, A., Dept of Community Medicine and Rehabilitation/Forensic Medicine, Umeå University, Umeå, Sweden; Kubat, B., Faculty of Health, Medicine and Life Science, Maastricht University, Maastricht, Netherlands; Kumar, A., Forensic Medicine and Toxicology, All India Institute of Medical SciencesNew Delhi, India; Payne-James, J.J., William Harvey Research Institute, Queen Mary University of London, London, UK, United Kingdom; Rubanzana, W.G., Department of Epidemiology and Biostatistics, University of Rwanda College of Medicine and Health Sciences, School of Public Health, Kigali, Rwanda; Uhrenholt, L., Department of Forensic Medicine, Section of Forensic Pathology, Aarhus University, Aarhus, Denmark; Freeman, M.D., Care and Public Health Research Institute (CAPHRI), Maastricht University Medical Center+, Maastricht, Netherlands; Zeegers, M.P., Care and Public Health Research Institute (CAPHRI), Maastricht University Medical Center+, Maastricht, Netherlands |
Introduction: Most findings of forensic pathology examinations are presented as written reports. There are currently no internationally accepted recommendations for writing forensic pathology reports. Existing recommendations are also varied and reflect the differences in the scope and role of forensic medical services and local settings in which they are to be implemented. The legal fact-finder thus faces wide variation in the quality of forensic pathology reports, which poses a threat to the reliability of legal decision-making. To address this issue, the development of the “PERFORM-P (Principles of Evidence-based Reporting in FORensic Medicine-Pathology version)” was undertaken. The goal of the PERFORM-P is to provide common practice recommendations adaptable to local requirements to promote evidence-based practice (EBP) in forensic pathology. Methods: An international consensus study was conducted in three phases by (1) developing a long-list of items to be considered in the reporting recommendations, (2) conducting a Delphi process (an iterative survey method to transform individual opinions into group consensus) with international forensic pathologists, and (3) designing the PERFORM-P prototype and its accompanying manual. Results: With assistance from 106 forensic pathologists/forensic medical practitioners from 41 countries, the PERFORM-P was developed. The PERFORM-P consists of a list of 61 items to be included in a forensic pathology report, which is accompanied by its Explanation and Elaboration (E&E) document. Discussion: To prepare forensic pathology (postmortem) reports that incorporate principles of evidence-based practice, internationally accepted recommendations might be helpful. The PERFORM-P identifies recommendations for necessary elements to include in a forensic pathology report. PERFORM-P can be applied to a wide range of matters requiring forensic pathological analysis, acceptable to forensic pathologists from a representative selection of jurisdictions and medico-legal systems. © 2021 The Authors |
Delphi study; Evidence-based practice; Forensic medicine; Forensic pathology; Reporting guides |
article; consensus; decision making; Delphi study; evidence based practice center; forensic pathology; human; pathologist; reliability; adult; consensus; evidence based practice; forensic pathology; international cooperation; middle aged; practice guideline; questionnaire; research; Adult; Consensus; Delphi Technique; Evidence-Based Practice; Forensic Pathology; Humans; Internationality; Middle Aged; Practice Guidelines as Topic; Research Report; Surveys and Questionnaires |
Elsevier Ireland Ltd |
03790738 |
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34474199 |
Article |
Q1 |
912 |
5047 |
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158 |
Mangunatmadja I., Ismael S., Sastroasmoro S., Suyatna F.D., van Nieuwenhuizen O., Cornelis van Huffelen A. |
57195717216;7003712283;6507794136;57303311300;7004334708;57226810329; |
Risk factors predicting intractability in focal epilepsy in children under 3 years of age: A cohort study |
2021 |
Epilepsy and Behavior |
123 |
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108234 |
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https://www.scopus.com/inward/record.uri?eid=2-s2.0-85112784416&doi=10.1016%2fj.yebeh.2021.108234&partnerID=40&md5=4d05d9ec38151cc168fae550bc699834 |
Department of Child Health, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Department of Clinical Pharmacology, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Department of Child Neurology, University Medical Center Utrecht, Netherlands; Department of Clinical Neurophysiology, University Medical Center Utrecht, Netherlands |
Mangunatmadja, I., Department of Child Health, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Ismael, S., Department of Child Health, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Sastroasmoro, S., Department of Child Health, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Suyatna, F.D., Department of Clinical Pharmacology, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; van Nieuwenhuizen, O., Department of Child Neurology, University Medical Center Utrecht, Netherlands; Cornelis van Huffelen, A., Department of Clinical Neurophysiology, University Medical Center Utrecht, Netherlands |
Background: Focal onset epilepsy carries a higher risk of intractability than generalized onset epilepsy. Knowledge of the risk factors of intractability will help guide the treatment of children with focal epilepsy. In addition to risk factors present at initial diagnosis, the evolution of clinical and electroencephalographic features may also play a role in predicting intractability. Methods: A prospective cohort study was done on children aged one month to three years with newly diagnosed focal epilepsy. Initial treatment of carbamazepine was given according to a standard protocol after assessment of clinical manifestations, neurologic and developmental status, EEG, and brain MRI. Depending on response to therapy, subjects may also receive valproic acid or phenobarbitone following the protocol. Follow-up was done in the second week and every month thereafter. At the end of the study period, seizure type was re-assessed and a repeat neurological and developmental examination and EEG was obtained to evaluate the role of clinical and EEG evolution in predicting intractability. Results: Out of 71 subjects, 21 (29.6%) had intractable epilepsy at the end of the study period. Age of onset (p = 0.216) and neurological status (p = 0.052) were not associated with intractable epilepsy. On logistic regression analysis, evolution of seizure type (p < 0.001; RR 56.45; 95%CI 6.56 to 485.85) and evolution of background EEG rhythm (p < 0.001; RR 56.51; 95%CI 2.77 to 1152.16) were significantly associated with intractable epilepsy. Conclusions: Changes in seizure type and baseline EEG rhythm may predict intractability in children one month to three years of age with focal epilepsy. © 2021 |
Electroencephalography; Focal epilepsy; Intractable; Seizure |
carbamazepine; phenobarbital; valproic acid; anticonvulsive agent; Article; cerebral palsy; child; cohort analysis; electroencephalography; epileptic discharge; focal epilepsy; follow up; human; intractable epilepsy; major clinical study; monotherapy; nuclear magnetic resonance imaging; preschool child; risk factor; focal epilepsy; prospective study; risk factor; Anticonvulsants; Child; Child, Preschool; Cohort Studies; Electroencephalography; Epilepsies, Partial; Humans; Prospective Studies; Risk Factors |
Academic Press Inc. |
15255050 |
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34416519 |
Article |
Q2 |
993 |
4418 |
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159 |
Sun X., Li R., Cai Y., Al-Herz A., Lahiri M., Choudhury M.R., Hidayat R., Suryana B.P.P., Kaneko Y., Fujio K., Van Hung N., Pandya S., Pang L.K., Katchamart W., Sigdel K.R., Paudyal B., Narongroeknawin P., Chevaisrakul P., Sun F., Lu Y., Ho C., Yeap S.S., Li Z., on behalf of APLAR RA SIG group |
57211390694;57026629100;56599490900;6508020635;26039213500;55408508400;37067327300;15728721800;8409247100;55029631300;57226144210;7103287746;57226150004;26654177400;56123182100;9244632800;35099091000;57191876780;57201927847;57226146642;57226138308;6701698220;57202324922; |
Clinical remission of rheumatoid arthritis in a multicenter real-world study in Asia-Pacific region |
2021 |
The Lancet Regional Health - Western Pacific |
15 |
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100240 |
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https://www.scopus.com/inward/record.uri?eid=2-s2.0-85112352039&doi=10.1016%2fj.lanwpc.2021.100240&partnerID=40&md5=ef847be2cdf076f3416d77f746dcd1cd |
Department of Rheumatology & Immunology, Peking University People's Hospital, 11 Xizhimen South St.Beijing 100044, China; Department of Rheumatology & Immunology, Peking University Shenzhen Hospital, Shenzhen, China; Rheumatology Unit, Department of Internal Medicine, Al-Amiri Hospital, Kuwait City, Kuwait; Department of Medicine, Yong Loo Lin School of Medicine, National University of Singapore, Singapore; Department of Rheumatology, Bangabandhu Sheikh Mujib Medical UniversityDhaka, Bangladesh; Department of Internal Medicine, Cipto Mangunkusumo National Hospital Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Rheumatology Division, Internal Medicine Department, Brawijaya University - Saiful Anwar Hospital, Indonesia; Division of Rheumatology, Department of Internal Medicine, Keio University School of MedicineTokyo, Japan; Department of Allergy and Rheumatology, Graduate School of Medicine, The University of TokyoTokyo, Japan; Department of Rheumatology, Bach Mai Hospital, Giai Phong Road, Dong Da DistrictHanoi, Viet Nam; Vedanta institute of medical sciences and VS hospital, Ahmedabad, India; Department of Rheumatology, Allergy and Immunology, Tan Tock Seng Hospital, Singapore; Division of Rheumatology, Department of Medicine, Faculty of Medicine Siriraj Hospital, Mahidol UniversityBangkok, Thailand; Department of Internal Medicine, Patan Academy of Health Sciences, Kathmandu, Nepal; Division of Rheumatology, Department of Medicine, Phramongkutklao Hospital and College of MedicineBangkok, Thailand; Division of Allergy, Immunology and Rheumatology, Department of Medicine, Faculty of Medicine Ramathibodi Hospital, Mahidol UniversityBangkok, Thailand; Department of Epidemiology and Biostatistics, School of Public Health, Peking University, 38 Xueyuan Road, Haidian DistrictBeijing 100191, China; School of Mathematical Science, Nankai University, No. 94 Weijin Road, Nankai DistrictTianjin 300071, China; Division of Rheumatology, Dept of Medicine, The University of Hong Kong, Hong Kong SAR, Hong Kong; Department of Medicine, Subang Jaya Medical Centre, Selangor, Malaysia |
Sun, X., Department of Rheumatology & Immunology, Peking University People's Hospital, 11 Xizhimen South St.Beijing 100044, China; Li, R., Department of Rheumatology & Immunology, Peking University People's Hospital, 11 Xizhimen South St.Beijing 100044, China; Cai, Y., Department of Rheumatology & Immunology, Peking University Shenzhen Hospital, Shenzhen, China; Al-Herz, A., Rheumatology Unit, Department of Internal Medicine, Al-Amiri Hospital, Kuwait City, Kuwait; Lahiri, M., Department of Medicine, Yong Loo Lin School of Medicine, National University of Singapore, Singapore; Choudhury, M.R., Department of Rheumatology, Bangabandhu Sheikh Mujib Medical UniversityDhaka, Bangladesh; Hidayat, R., Department of Internal Medicine, Cipto Mangunkusumo National Hospital Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Suryana, B.P.P., Rheumatology Division, Internal Medicine Department, Brawijaya University - Saiful Anwar Hospital, Indonesia; Kaneko, Y., Division of Rheumatology, Department of Internal Medicine, Keio University School of MedicineTokyo, Japan; Fujio, K., Department of Allergy and Rheumatology, Graduate School of Medicine, The University of TokyoTokyo, Japan; Van Hung, N., Department of Rheumatology, Bach Mai Hospital, Giai Phong Road, Dong Da DistrictHanoi, Viet Nam; Pandya, S., Vedanta institute of medical sciences and VS hospital, Ahmedabad, India; Pang, L.K., Department of Rheumatology, Allergy and Immunology, Tan Tock Seng Hospital, Singapore; Katchamart, W., Division of Rheumatology, Department of Medicine, Faculty of Medicine Siriraj Hospital, Mahidol UniversityBangkok, Thailand; Sigdel, K.R., Department of Internal Medicine, Patan Academy of Health Sciences, Kathmandu, Nepal; Paudyal, B., Department of Internal Medicine, Patan Academy of Health Sciences, Kathmandu, Nepal; Narongroeknawin, P., Division of Rheumatology, Department of Medicine, Phramongkutklao Hospital and College of MedicineBangkok, Thailand; Chevaisrakul, P., Division of Allergy, Immunology and Rheumatology, Department of Medicine, Faculty of Medicine Ramathibodi Hospital, Mahidol UniversityBangkok, Thailand; Sun, F., Department of Epidemiology and Biostatistics, School of Public Health, Peking University, 38 Xueyuan Road, Haidian DistrictBeijing 100191, China; Lu, Y., School of Mathematical Science, Nankai University, No. 94 Weijin Road, Nankai DistrictTianjin 300071, China; Ho, C., Division of Rheumatology, Dept of Medicine, The University of Hong Kong, Hong Kong SAR, Hong Kong; Yeap, S.S., Department of Medicine, Subang Jaya Medical Centre, Selangor, Malaysia; Li, Z., Department of Rheumatology & Immunology, Peking University People's Hospital, 11 Xizhimen South St.Beijing 100044, China; on behalf of APLAR RA SIG group |
Background: Clinical remission is an attainable goal for Rheumatoid Arthritis (RA). However, data on RA remission rates from multinational studies in the Asia-Pacific region are limited. We conducted a cross-sectional multicentric study to evaluate the clinical remission status and the related factors in RA patients in the Asia-Pacific region. Methods: RA patients receiving standard care were enrolled consecutively from 17 sites in 11 countries from APLAR RA SIG group. Data were collected on-site by rheumatologists with a standardized case-report form. Remission was analyzed by different definitions including disease activity score using 28 joints (DAS28) based on ESR and CRP, clinical disease activity index (CDAI), simplified disease activity index (SDAI), Boolean remission definition, and clinical deep remission (CliDR). Logistic regression was used to determine related factors of remission. Findings: A total of 2010 RA patients was included in the study, the overall remission rates were 62•3% (DAS28-CRP), 35•5% (DAS28-ESR), 30•8% (CDAI), 26•5% (SDAI), 24•7% (Boolean), and 17•1% (CliDR), respectively, and varied from countries to countries in the Asia-Pacific region. Biological and targeted synthetic disease-modifying antirheumatic drugs (b/tsDMARDs) prescription rate was low (17•9%). Compared to patients in non-remission, patients in remission had higher rates of b/tsDMARDs usage and lower rates of GC usage. The favorable related factors were male sex, younger age, fewer comorbidities, fewer extra-articular manifestations (EAM), and use of b/tsDMARDs, while treatment with GC was negatively related to remission. Interpretation: Remission rates were low and varied in the Asia-Pacific region. Treatment with b/tsDMARDs and less GC usage were related to higher remission rate. There is an unmet need for RA remission in the Asia-Pacific region. © 2021 |
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Elsevier Ltd |
26666065 |
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Article |
#N/A |
#N/A |
#N/A |
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161 |
Ramlan A.A., Lestari M.I., Banadji Y., Arif S.K. |
57195941841;57219312983;57225895278;57189846423; |
A national survey of capnography utilization among anaesthesiologists in Indonesia |
2021 |
Trends in Anaesthesia and Critical Care |
40 |
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9 |
13 |
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https://www.scopus.com/inward/record.uri?eid=2-s2.0-85109639916&doi=10.1016%2fj.tacc.2021.06.004&partnerID=40&md5=b17959a3c3b317991ee9e2a914ec9547 |
Department of Anaesthesiology and Intensive Care, Faculty of Medicine Universitas Indonesia, Cipto Mangunkusumo National HospitalJakarta, Indonesia; Department of Anaesthesiology and Intensive Care, Faculty of Medicine Universitas Sriwijaya, Palembang, Indonesia; Department of Anaesthesiology and Intensive Care, Faculty of Medicine Universitas Hasanuddin, Makassar, Indonesia; Indonesian Society of Anaesthesiology and Intensive CareJakarta, Indonesia |
Ramlan, A.A., Department of Anaesthesiology and Intensive Care, Faculty of Medicine Universitas Indonesia, Cipto Mangunkusumo National HospitalJakarta, Indonesia, Indonesian Society of Anaesthesiology and Intensive CareJakarta, Indonesia; Lestari, M.I., Department of Anaesthesiology and Intensive Care, Faculty of Medicine Universitas Sriwijaya, Palembang, Indonesia, Indonesian Society of Anaesthesiology and Intensive CareJakarta, Indonesia; Banadji, Y., Indonesian Society of Anaesthesiology and Intensive CareJakarta, Indonesia; Arif, S.K., Department of Anaesthesiology and Intensive Care, Faculty of Medicine Universitas Hasanuddin, Makassar, Indonesia, Indonesian Society of Anaesthesiology and Intensive CareJakarta, Indonesia |
Background: Capnography allows health-care providers to continuously monitor the concentration or partial pressure of carbon dioxide in respiratory gas. The American Society of Anaesthesiologists includes end-tidal carbon dioxide monitoring as mandatory monitoring for patients under sedation and anaesthesia. However, capnography is not widely considered for standard patient monitoring in Indonesia. We aim to investigate the utilization of capnography and reasons for lack of use among anaesthesiologists in Indonesia. Methods: An internet-based questionnaire was distributed to participants of an online anaesthesiology national meeting. Data was collected and managed using REDCap electronic data capture tools hosted at Faculty of Medicine Universitas Indonesia. Results: We received 421 respondents' replies nationwide. Replies from anaesthesiologists (n = 367) was used for data analysis. 55.3% (n = 203) reported the availability of capnography in their hospitals. Approximately 77 (21%) of respondents utilize capnography routinely for intraoperative monitoring, 132 (36%) never use capnography. Only 59 (16%) routinely use capnography for intubation confirmation. The utilization of capnography outside the operating theatre was even lower. As many of 249 (67.9%) never use capnography for monitoring during procedural sedation, while 278 (75.8%) do not utilize capnography during patient transfer. Conclusion: The utilization of capnography for intraoperative monitoring is adopted only by half of anaesthesiologists in Indonesia. Outside the operating theatre capnography use is still limited. Capnography as a standard of care should be implemented in all health care institutions in Indonesia. © 2021 Elsevier Ltd |
Capnography; Intra-operative monitoring; Standard monitoring |
anesthesiologist; Article; capnometry; controlled study; health care quality; health care utilization; human; Indonesia; Internet; intraoperative monitoring; patient safety; patient transport; sedation |
Churchill Livingstone |
22108440 |
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Article |
Q3 |
213 |
18603 |
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165 |
Vandenplas Y., Hegar B., Munasir Z., Astawan M., Juffrie M., Bardosono S., Sekartini R., Basrowi R.W., Wasito E. |
57223670656;6506273944;7801694370;55622754000;6603321832;21933841000;57224503576;57024210400;6506940239; |
The role of soy plant-based formula supplemented with dietary fiber to support children's growth and development: An expert opinion |
2021 |
Nutrition |
90 |
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111278 |
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1 |
https://www.scopus.com/inward/record.uri?eid=2-s2.0-85106303526&doi=10.1016%2fj.nut.2021.111278&partnerID=40&md5=6f39985da49e44dfd1fa5832b4927b0a |
KidZ Health Castle, UZ Brussel, Vrije Universiteit Brussel, Belgium; Department of Pediatric, Faculty of Medicine, Universitas Indonesia, Cipto Mangunkusumo General HospitalJakarta, Indonesia; Department of Food Science and Technology, IPB University, Bogor, Indonesia; Department of Child Health, Faculty of Medicine, Universitas Gajah MadaYogyakarta, Indonesia; Department of Nutrition, Faculty of Medicine, Universitas Indonesia, Cipto Mangunkusumo General HospitalJakarta, Indonesia; Danone Specialized Nutrition IndonesiaJakarta, Indonesia |
Vandenplas, Y., KidZ Health Castle, UZ Brussel, Vrije Universiteit Brussel, Belgium; Hegar, B., Department of Pediatric, Faculty of Medicine, Universitas Indonesia, Cipto Mangunkusumo General HospitalJakarta, Indonesia; Munasir, Z., Department of Pediatric, Faculty of Medicine, Universitas Indonesia, Cipto Mangunkusumo General HospitalJakarta, Indonesia; Astawan, M., Department of Food Science and Technology, IPB University, Bogor, Indonesia; Juffrie, M., Department of Child Health, Faculty of Medicine, Universitas Gajah MadaYogyakarta, Indonesia; Bardosono, S., Department of Nutrition, Faculty of Medicine, Universitas Indonesia, Cipto Mangunkusumo General HospitalJakarta, Indonesia; Sekartini, R., Department of Pediatric, Faculty of Medicine, Universitas Indonesia, Cipto Mangunkusumo General HospitalJakarta, Indonesia; Basrowi, R.W., Danone Specialized Nutrition IndonesiaJakarta, Indonesia; Wasito, E., Danone Specialized Nutrition IndonesiaJakarta, Indonesia |
Objectives: Soy-based formula has evolved in usage and processing technology since its introduction in 1909, and has been used as substitute formula for infants or children with cow milk allergy since 1929. At present, personal opinions, religious background, availability, palatability, and cost are part of the reasons soy-based formula is chosen. Technology in processing soy-based formula has evolved from using soy flour to soy protein isolate, which provides advantages. However, concerns remain regarding the impact of its use on the growth and development of children. Methods: An expert meeting, attended by 12 experts, was initiated in Jakarta, Indonesia, to obtain an evidence-based consensus on the role of soy protein isolate formula, as well as its nutritional value to support growth and development. Results: Ensuring that plant-based formula (i.e., soy protein isolate formula) is fortified with key nutrients, such as calcium, iron, and dietary fiber is important. Conclusions: Consensus was achieved, concluding that soy protein isolate formula is safe, affordable, and an alternative option for cow's milk–based formula for term infants. © 2021 The Authors |
Child growth and development; Expert opinion; Soy-based infant formula |
calcium; iron; soybean protein; artificial milk; child growth; developmental stage; diet supplementation; dietary fiber; human; nutritional value; patient safety; priority journal; Review; soybean; soybean meal; animal; artificial milk; bovine; child; dietary fiber; expert witness; female; infant; milk allergy; Animals; Cattle; Child; Dietary Fiber; Expert Testimony; Female; Humans; Infant; Infant Formula; Milk Hypersensitivity; Soybean Proteins |
Elsevier Inc. |
08999007 |
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34004412 |
Review |
Q2 |
1002 |
4372 |
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171 |
Pudjiadi A.H., Putri N.D., Sjakti H.A., Yanuarso P.B., Gunardi H., Roeslani R.D., Pasaribu A.D., Nurmalia L.D., Sambo C.M., Ugrasena I.D.G., Soeroso S., Firman A., Muryawan H., Setyanto D.B., Citraresmi E., Effendi J.A., Habibah L., Octaviantie P.D., Utami I.N.A., Prawira Y., Kaswandani N., Alam A., Kadafi K.T., Pulungan A.B. |
18435202300;57200573842;57195720458;57205428706;56510252700;57191512707;57287717900;57288262700;57287718000;57224730593;15133254800;57215582843;57287718100;57203009929;57224512641;57287899600;57287899700;57287718200;57287718300;55455747000;57195941745;57201672408;57211313656;57192905981; |
Pediatric COVID-19: Report From Indonesian Pediatric Society Data Registry |
2021 |
Frontiers in Pediatrics |
9 |
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716898 |
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1 |
https://www.scopus.com/inward/record.uri?eid=2-s2.0-85116558206&doi=10.3389%2ffped.2021.716898&partnerID=40&md5=8c294f39457ac77d477f3bb1d2dd9eb4 |
The Indonesian Pediatric Society, Jakarta, Indonesia; Department of Pediatrics, Faculty of Medicine, Cipto Mangunkusumo National Central Hospital, Universitas Indonesia, Jakarta, Indonesia; Department of Pediatrics, Faculty of Medicine, Dr. Soetomo Hospital, Universitas Airlangga, Surabaya, Indonesia; Department of Pediatrics, Faculty of Medicine, Hasan Sadikin Hospital, Universitas Padjajaran, Bandung, Indonesia; Department of Pediatrics, Faculty of Medicine, Dr. Kariadi Hospital, Universitas Diponegoro, Semarang, Indonesia; Department of Pediatrics, Harapan Kita Women and Children Hospital, Jakarta, Indonesia; Department of Pediatrics, Fatmawati Hospital, Jakarta, Indonesia; Department of Pediatrics, Faculty of Medicine, Dr. Saiful Anwar Hospital, Universitas Brawijaya, Malang, Indonesia |
Pudjiadi, A.H., The Indonesian Pediatric Society, Jakarta, Indonesia, Department of Pediatrics, Faculty of Medicine, Cipto Mangunkusumo National Central Hospital, Universitas Indonesia, Jakarta, Indonesia; Putri, N.D., The Indonesian Pediatric Society, Jakarta, Indonesia, Department of Pediatrics, Faculty of Medicine, Cipto Mangunkusumo National Central Hospital, Universitas Indonesia, Jakarta, Indonesia; Sjakti, H.A., The Indonesian Pediatric Society, Jakarta, Indonesia, Department of Pediatrics, Faculty of Medicine, Cipto Mangunkusumo National Central Hospital, Universitas Indonesia, Jakarta, Indonesia; Yanuarso, P.B., The Indonesian Pediatric Society, Jakarta, Indonesia, Department of Pediatrics, Faculty of Medicine, Cipto Mangunkusumo National Central Hospital, Universitas Indonesia, Jakarta, Indonesia; Gunardi, H., The Indonesian Pediatric Society, Jakarta, Indonesia, Department of Pediatrics, Faculty of Medicine, Cipto Mangunkusumo National Central Hospital, Universitas Indonesia, Jakarta, Indonesia; Roeslani, R.D., The Indonesian Pediatric Society, Jakarta, Indonesia, Department of Pediatrics, Faculty of Medicine, Cipto Mangunkusumo National Central Hospital, Universitas Indonesia, Jakarta, Indonesia; Pasaribu, A.D., The Indonesian Pediatric Society, Jakarta, Indonesia; Nurmalia, L.D., The Indonesian Pediatric Society, Jakarta, Indonesia; Sambo, C.M., The Indonesian Pediatric Society, Jakarta, Indonesia; Ugrasena, I.D.G., The Indonesian Pediatric Society, Jakarta, Indonesia, Department of Pediatrics, Faculty of Medicine, Dr. Soetomo Hospital, Universitas Airlangga, Surabaya, Indonesia; Soeroso, S., The Indonesian Pediatric Society, Jakarta, Indonesia; Firman, A., The Indonesian Pediatric Society, Jakarta, Indonesia, Department of Pediatrics, Faculty of Medicine, Hasan Sadikin Hospital, Universitas Padjajaran, Bandung, Indonesia; Muryawan, H., The Indonesian Pediatric Society, Jakarta, Indonesia, Department of Pediatrics, Faculty of Medicine, Dr. Kariadi Hospital, Universitas Diponegoro, Semarang, Indonesia; Setyanto, D.B., The Indonesian Pediatric Society, Jakarta, Indonesia, Department of Pediatrics, Faculty of Medicine, Cipto Mangunkusumo National Central Hospital, Universitas Indonesia, Jakarta, Indonesia; Citraresmi, E., The Indonesian Pediatric Society, Jakarta, Indonesia, Department of Pediatrics, Harapan Kita Women and Children Hospital, Jakarta, Indonesia; Effendi, J.A., The Indonesian Pediatric Society, Jakarta, Indonesia, Department of Pediatrics, Fatmawati Hospital, Jakarta, Indonesia; Habibah, L., The Indonesian Pediatric Society, Jakarta, Indonesia; Octaviantie, P.D., Department of Pediatrics, Faculty of Medicine, Cipto Mangunkusumo National Central Hospital, Universitas Indonesia, Jakarta, Indonesia; Utami, I.N.A., The Indonesian Pediatric Society, Jakarta, Indonesia; Prawira, Y., The Indonesian Pediatric Society, Jakarta, Indonesia, Department of Pediatrics, Faculty of Medicine, Cipto Mangunkusumo National Central Hospital, Universitas Indonesia, Jakarta, Indonesia; Kaswandani, N., The Indonesian Pediatric Society, Jakarta, Indonesia, Department of Pediatrics, Faculty of Medicine, Cipto Mangunkusumo National Central Hospital, Universitas Indonesia, Jakarta, Indonesia; Alam, A., The Indonesian Pediatric Society, Jakarta, Indonesia, Department of Pediatrics, Faculty of Medicine, Hasan Sadikin Hospital, Universitas Padjajaran, Bandung, Indonesia; Kadafi, K.T., The Indonesian Pediatric Society, Jakarta, Indonesia, Department of Pediatrics, Faculty of Medicine, Dr. Saiful Anwar Hospital, Universitas Brawijaya, Malang, Indonesia; Pulungan, A.B., The Indonesian Pediatric Society, Jakarta, Indonesia, Department of Pediatrics, Faculty of Medicine, Cipto Mangunkusumo National Central Hospital, Universitas Indonesia, Jakarta, Indonesia |
Background: Indonesia has a high number of COVID-19 cases and mortalities relative to not only among the Asia Pacific region but the world. Children were thought to be less affected by the virus compared to adults. Most of the public data reported combined data between adults and children. The Indonesian Pediatric Society (IPS) was involved in the COVID-19 response, especially in the area of child health. One of IPS's activities is collecting data registries from each of their chapters to provide a better understanding of COVID-19 in children. Objective: The objective of this study was to share the data of suspected and confirmed COVID-19 cases in children from IPS's COVID-19 data registry. Method: This is a retrospective study from the IPS's COVID-19 registry data. We collected the data of COVID-19 in children during March to December 2020 from each of the IPS chapters. We analyzed the prevalence, case fatality rate (CFR), age groups, diagnosis, and comorbidities of the children diagnosed with COVID-19. Result: As of December 21, 2020, there were 35,506 suspected cases of children with COVID-19. In total, there were 522 deaths, with a case fatality ratio (CFR) of 1.4. There were 37,706 confirmed cases with 175 fatalities (CFR 0.46). The highest mortality in confirmed COVID-19 cases was from children ages 10–18 years (42 out of 159 cases: 26%). The most common comorbidity and diagnosis found were malignancy (17.3%) and respiratory failure (54.5%). Conclusion: The CFR of confirmed COVID-19 cases in children in Indonesia is high and should be a major public concern. © Copyright © 2021 Pudjiadi, Putri, Sjakti, Yanuarso, Gunardi, Roeslani, Pasaribu, Nurmalia, Sambo, Ugrasena, Soeroso, Firman, Muryawan, Setyanto, Citraresmi, Effendi, Habibah, Octaviantie, Utami, Prawira, Kaswandani, Alam, Kadafi and Pulungan. |
children; comorbidities; COVID-19; Indonesia; mortality |
adolescent; adult; Article; case fatality rate; cause of death; child; comorbidity; coronavirus disease 2019; human; Indonesia; major clinical study; malignant neoplasm; medical society; mortality; pediatrics; prevalence; questionnaire; register; respiratory failure; retrospective study; sepsis; septic shock |
Frontiers Media S.A. |
22962360 |
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Article |
Q1 |
960 |
4641 |
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175 |
Tamba R.P., Moenadjat Y. |
47761736600;57190371576; |
Oral Spermine Supplementation in Gestated Rabbit: A Study on Villi Height of Immature Intestines |
2021 |
Frontiers in Surgery |
8 |
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721560 |
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https://www.scopus.com/inward/record.uri?eid=2-s2.0-85115713070&doi=10.3389%2ffsurg.2021.721560&partnerID=40&md5=ef2b810fab926ddb3b4313b8d20045f5 |
Faculty of Medicine, Department of Surgery Cipto, Mangunkusumo General Hospital, Universitas Indonesia, Jakarta, Indonesia |
Tamba, R.P., Faculty of Medicine, Department of Surgery Cipto, Mangunkusumo General Hospital, Universitas Indonesia, Jakarta, Indonesia; Moenadjat, Y., Faculty of Medicine, Department of Surgery Cipto, Mangunkusumo General Hospital, Universitas Indonesia, Jakarta, Indonesia |
Introduction: Immature intestines are the major problem in prematurity. Postnatal oral spermine has been shown in studies to improve intestinal maturation in rats and piglets. This study aimed to find out the efficacy of spermine in rabbits during gestation. Method: An experimental study was done in an unblinded, randomized manner on those treated with and without spermine administration. A morphological examination of hematoxylin–eosin-stained villi was performed under a light microscope with a focus on villi height. Data were subjected to analysis. Results: The median of the spermine-treated group was found to be higher at 24, 26, and 28 days than the non-spermine group, but was not significantly different. Conclusion: Oral spermine supplementation during gestation might improve intestinal villi height in immature rabbit intestines. © Copyright © 2021 Tamba and Moenadjat. |
gestation; immature intestines; rabbit; spermine; villi height |
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Frontiers Media S.A. |
2296875X |
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Article |
Q2 |
483 |
10376 |
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176 |
Nakhaei P., Margiana R., Bokov D.O., Abdelbasset W.K., Jadidi Kouhbanani M.A., Varma R.S., Marofi F., Jarahian M., Beheshtkhoo N. |
57226413840;56685900600;56845561300;57208873763;57219274421;7201793587;57199650994;16241593900;57201547070; |
Liposomes: Structure, Biomedical Applications, and Stability Parameters With Emphasis on Cholesterol |
2021 |
Frontiers in Bioengineering and Biotechnology |
9 |
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705886 |
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4 |
https://www.scopus.com/inward/record.uri?eid=2-s2.0-85115653337&doi=10.3389%2ffbioe.2021.705886&partnerID=40&md5=0d6cee3ed2be3a97e6c2beb3d6c668b5 |
School of Medicine, Tehran University of Medical Sciences, Tehran, Iran; Department of Anatomy, Faculty of Medicine, Universitas Indonesia, Depok, Indonesia; Cipto Mangunkusumo Hospital, The National Referral Hospital, Central Jakarta, Indonesia; Master’s Programme Biomedical Sciences, Faculty of Medicine, Universitas Indonesia, Depok, Indonesia; Institute of Pharmacy, Sechenov First Moscow State Medical University, Moscow, Russian Federation; Laboratory of Food Chemistry, Federal Research Center of Nutrition, Biotechnology, and Food Safety, Moscow, Russian Federation; Department of Health and Rehabilitation Sciences, College of Applied Medical Sciences, Prince Sattam Bin Abdulaziz University, Al Kharj, Saudi Arabia; Department of Physical Therapy, Kasr Al-Aini Hospital, Cairo University, Giza, Egypt; Department of Medical Nanotechnology, School of Advanced Medical Sciences and Technologies, Shiraz University of Medical Sciences, Shiraz, Czech Republic; Regional Centre of Advanced Technologies and Materials, Czech Advanced Technology and Research Institute, Palacký University in Olomouc, Olomouc, Czech Republic; Department of Hematology, Faculty of Medicine, Tabriz University of Medical Sciences, Tabriz, Iran; Toxicology and Chemotherapy Unit (G401), German Cancer Research Center, Heidelberg, Germany |
Nakhaei, P., School of Medicine, Tehran University of Medical Sciences, Tehran, Iran; Margiana, R., Department of Anatomy, Faculty of Medicine, Universitas Indonesia, Depok, Indonesia, Cipto Mangunkusumo Hospital, The National Referral Hospital, Central Jakarta, Indonesia, Master’s Programme Biomedical Sciences, Faculty of Medicine, Universitas Indonesia, Depok, Indonesia; Bokov, D.O., Institute of Pharmacy, Sechenov First Moscow State Medical University, Moscow, Russian Federation, Laboratory of Food Chemistry, Federal Research Center of Nutrition, Biotechnology, and Food Safety, Moscow, Russian Federation; Abdelbasset, W.K., Department of Health and Rehabilitation Sciences, College of Applied Medical Sciences, Prince Sattam Bin Abdulaziz University, Al Kharj, Saudi Arabia, Department of Physical Therapy, Kasr Al-Aini Hospital, Cairo University, Giza, Egypt; Jadidi Kouhbanani, M.A., Department of Medical Nanotechnology, School of Advanced Medical Sciences and Technologies, Shiraz University of Medical Sciences, Shiraz, Czech Republic; Varma, R.S., Regional Centre of Advanced Technologies and Materials, Czech Advanced Technology and Research Institute, Palacký University in Olomouc, Olomouc, Czech Republic; Marofi, F., Department of Hematology, Faculty of Medicine, Tabriz University of Medical Sciences, Tabriz, Iran; Jarahian, M., Toxicology and Chemotherapy Unit (G401), German Cancer Research Center, Heidelberg, Germany; Beheshtkhoo, N., Department of Medical Nanotechnology, School of Advanced Medical Sciences and Technologies, Shiraz University of Medical Sciences, Shiraz, Czech Republic |
Liposomes are essentially a subtype of nanoparticles comprising a hydrophobic tail and a hydrophilic head constituting a phospholipid membrane. The spherical or multilayered spherical structures of liposomes are highly rich in lipid contents with numerous criteria for their classification, including structural features, structural parameters, and size, synthesis methods, preparation, and drug loading. Despite various liposomal applications, such as drug, vaccine/gene delivery, biosensors fabrication, diagnosis, and food products applications, their use encounters many limitations due to physico-chemical instability as their stability is vigorously affected by the constituting ingredients wherein cholesterol performs a vital role in the stability of the liposomal membrane. It has well established that cholesterol exerts its impact by controlling fluidity, permeability, membrane strength, elasticity and stiffness, transition temperature (Tm), drug retention, phospholipid packing, and plasma stability. Although the undetermined optimum amount of cholesterol for preparing a stable and controlled release vehicle has been the downside, but researchers are still focused on cholesterol as a promising material for the stability of liposomes necessitating explanation for the stability promotion of liposomes. Herein, the prior art pertaining to the liposomal appliances, especially for drug delivery in cancer therapy, and their stability emphasizing the roles of cholesterol. © Copyright © 2021 Nakhaei, Margiana, Bokov, Abdelbasset, Jadidi Kouhbanani, Varma, Marofi, Jarahian and Beheshtkhoo. |
cholesterol; compounds; lipids; liposome; stability |
Automobile manufacture; Chemical stability; Controlled drug delivery; Food products; Liposomes; Medical applications; Phospholipids; Plasma stability; Targeted drug delivery; Application parameters; Biomedical applications; Compound; Hydrophilic heads; Hydrophobic tails; Liposome structures; Multi-layered; Phospholipid membrane; Spherical structures; Stability parameters; Cholesterol |
Frontiers Media S.A. |
22964185 |
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Review |
Q1 |
1081 |
3891 |
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177 |
Karina K., Ekaputri K., Albert Biben J., Rosadi I., Rosliana I., Sobariah S., Sulaeha A.D., Andrew H., Afini I., Widyastuti T., Jusryanti J., Prestiani S.I., Donna I.M., Mutiara M.S., Habibi H. |
57212146678;57285088000;57284643500;57204720098;57186671400;57203547382;57226286645;57226282534;57211068324;57211074403;57284643600;57283770100;57284210300;57284210400;57222314524; |
Evaluation of plasma pdgf and vegf levels after systemic administration of activated autologous platelet-rich plasma |
2021 |
Biomedicine (India) |
41 |
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409 |
412 |
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https://www.scopus.com/inward/record.uri?eid=2-s2.0-85116318936&doi=10.51248%2f.v41i2.1047&partnerID=40&md5=b63a888f3eb59bb12b87fdd1bfa4f091 |
Klinik Hayandra, Yayasan Hayandra Peduli, Jl. Kramat VI No. 11, Jakarta Pusat, 10430, Indonesia; Hayandra Lab, Yayasan Hayandra Peduli, Jl. Kramat VI No. 11, Jakarta Pusat, 10430, Indonesia; Faculty of Medicine, Universitas Pembangunan Nasional Veteran, Jakarta, 12450, Indonesia; Pusat Kajian Stem Cell, Universitas Pembangunan Nasional Veteran, Jakarta, 12450, Indonesia; Department of Biology, Faculty of Mathematics and Natural Sciences, Mulawarman University, Samarinda, 752424, Indonesia; Faculty of Medicine, Universitas Indonesia, Jl. Salemba Raya no. 6, Jakarta Pusat, 10430, Indonesia |
Karina, K., Klinik Hayandra, Yayasan Hayandra Peduli, Jl. Kramat VI No. 11, Jakarta Pusat, 10430, Indonesia, Hayandra Lab, Yayasan Hayandra Peduli, Jl. Kramat VI No. 11, Jakarta Pusat, 10430, Indonesia, Faculty of Medicine, Universitas Pembangunan Nasional Veteran, Jakarta, 12450, Indonesia, Pusat Kajian Stem Cell, Universitas Pembangunan Nasional Veteran, Jakarta, 12450, Indonesia; Ekaputri, K., Klinik Hayandra, Yayasan Hayandra Peduli, Jl. Kramat VI No. 11, Jakarta Pusat, 10430, Indonesia; Albert Biben, J., Klinik Hayandra, Yayasan Hayandra Peduli, Jl. Kramat VI No. 11, Jakarta Pusat, 10430, Indonesia; Rosadi, I., Hayandra Lab, Yayasan Hayandra Peduli, Jl. Kramat VI No. 11, Jakarta Pusat, 10430, Indonesia, Department of Biology, Faculty of Mathematics and Natural Sciences, Mulawarman University, Samarinda, 752424, Indonesia; Rosliana, I., Hayandra Lab, Yayasan Hayandra Peduli, Jl. Kramat VI No. 11, Jakarta Pusat, 10430, Indonesia; Sobariah, S., Hayandra Lab, Yayasan Hayandra Peduli, Jl. Kramat VI No. 11, Jakarta Pusat, 10430, Indonesia; Sulaeha, A.D., Klinik Hayandra, Yayasan Hayandra Peduli, Jl. Kramat VI No. 11, Jakarta Pusat, 10430, Indonesia; Andrew, H., Hayandra Lab, Yayasan Hayandra Peduli, Jl. Kramat VI No. 11, Jakarta Pusat, 10430, Indonesia, Faculty of Medicine, Universitas Indonesia, Jl. Salemba Raya no. 6, Jakarta Pusat, 10430, Indonesia; Afini, I., Hayandra Lab, Yayasan Hayandra Peduli, Jl. Kramat VI No. 11, Jakarta Pusat, 10430, Indonesia; Widyastuti, T., Hayandra Lab, Yayasan Hayandra Peduli, Jl. Kramat VI No. 11, Jakarta Pusat, 10430, Indonesia; Jusryanti, J., Klinik Hayandra, Yayasan Hayandra Peduli, Jl. Kramat VI No. 11, Jakarta Pusat, 10430, Indonesia; Prestiani, S.I., Klinik Hayandra, Yayasan Hayandra Peduli, Jl. Kramat VI No. 11, Jakarta Pusat, 10430, Indonesia; Donna, I.M., Klinik Hayandra, Yayasan Hayandra Peduli, Jl. Kramat VI No. 11, Jakarta Pusat, 10430, Indonesia; Mutiara, M.S., Klinik Hayandra, Yayasan Hayandra Peduli, Jl. Kramat VI No. 11, Jakarta Pusat, 10430, Indonesia; Habibi, H., Klinik Hayandra, Yayasan Hayandra Peduli, Jl. Kramat VI No. 11, Jakarta Pusat, 10430, Indonesia |
Introduction and Aim: Activated autologous platelet-rich plasma (aaPRP) is becoming a popular therapy to accelerate healing in the field of plastic surgery. Platelets, which are abundant in aaPRP, can release many growth factors including platelet-derived growth factor (PDGF) and vascular endothelial growth factor (VEGF). This study aims to examine the plasma levels of PDGF and VEGF in healthy subjects after intravenous administration of aaPRP. Materials and Methods: Nine healthy patients with no prior history of metabolic disease were divided into two groups (control and experiment group). The treatment group which consists of six patients received intravenous aaPRP treatment. The preparation of aaPRP starts with the collection of 24 mL of whole blood in sodium citrate tubes followed a two-step centrifugation procedure and subsequent chemical activation. aaPRP was then administered intravenously to patients. Meanwhile, the control group received no intervention. Venous blood samples were taken before and one week after the treatment and the plasma PDGF and VEGF levels were determined by enzyme-linked immunosorbent assay (ELISA). Results: The treatment group showed statistically significant increase in VEGF after 7 days compared to before aaPRP administration. However, the change in PDGF levels of the treatment group was unnotable. Conclusion: The present findings indicate that intravenous administrations of activated aaPRP may increase plasma VEGF level up to 1 week after aaPRP administration. © 2021, Indian Association of Biomedical Scientists. All rights reserved. |
Activated autologous platelet-rich plasma (aaPRP); Platelet derived growth factor (PDGF); Vascular endothelial growth factor (VEGF) |
activated autologous platelet rich plasma; citrate sodium; platelet derived growth factor; thrombocyte concentrate; unclassified drug; vasculotropin; adult; Article; blood autotransfusion; blood chemistry; blood sampling; case control study; centrifugation; cohort analysis; controlled study; enzyme linked immunosorbent assay; female; human; human cell; male; metabolic disorder; middle aged; observational study; prospective study; protein blood level; thrombocyte rich plasma; venous blood |
Indian Association of Biomedical Scientists |
09702067 |
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Article |
Q4 |
106 |
29384 |
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181 |
Restuti R.D., Priyono H., Saleh R.R., Sriyana A.A. |
55261428300;57201550021;57391850200;57203022550; |
Clinical and intraoperative findings for dangerous chronic suppurative otitis media in paediatric cases |
2021 |
Pan African Medical Journal |
40 |
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174 |
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https://www.scopus.com/inward/record.uri?eid=2-s2.0-85122176797&doi=10.11604%2fpamj.2021.40.174.22291&partnerID=40&md5=cc2fdd7757d45b939c6c42c4fc2372de |
Otology Division, Ear Nose and Throat Department, Faculty of Medicine, Universitas Indonesia-Cipto Mangunkusumo General Hospital, Jakarta, Indonesia |
Restuti, R.D., Otology Division, Ear Nose and Throat Department, Faculty of Medicine, Universitas Indonesia-Cipto Mangunkusumo General Hospital, Jakarta, Indonesia; Priyono, H., Otology Division, Ear Nose and Throat Department, Faculty of Medicine, Universitas Indonesia-Cipto Mangunkusumo General Hospital, Jakarta, Indonesia; Saleh, R.R., Otology Division, Ear Nose and Throat Department, Faculty of Medicine, Universitas Indonesia-Cipto Mangunkusumo General Hospital, Jakarta, Indonesia; Sriyana, A.A., Otology Division, Ear Nose and Throat Department, Faculty of Medicine, Universitas Indonesia-Cipto Mangunkusumo General Hospital, Jakarta, Indonesia |
The number of complications in dangerous Chronic Suppurative Otitis Media (CSOM) remain high, especially in late presentation. Extensive disease with intratemporal and intracranial complications, especially in children, was commonly found in Cipto Mangunkusumo General Hospital (CMGH), a tertiary referral hospital. This was a retrospective study that used secondary data from 2017 to 2019 in CMGH. All paediatric patients with diagnoses of dangerous CSOM and who underwent surgery from January 2017 to June 2019 were included. Clinical and intraoperative findings were described in this study. Twenty paediatric patients underwent surgery in CMGH from 2017 to 2019; of that number, 17 had unilateral dangerous CSOM, and three had bilateral dangerous CSOM. All patients aged 2 to 18 years old underwent canal wall down technique surgery. Profound hearing loss was found in nine ears; severe loss, in four ears; moderately severe loss, in four ears; and moderate loss, in seven ears. The most common intraoperative finding was total ossicular destruction in 17/23 ears. Erosion of sigmoid sinus plate was found in 5/23 ears, with perisinus abscess occurring in one case. Tegmen erosion was found in 4/23 ears. Facial nerve dehiscence was found in seven ears (5 vertical segments, 2 horizontal segments) and two patients had facial nerve paralysis before surgery. Lateral semicircular canal (SCC) fistula was found in 6/23 ears. Late presentation in dangerous CSOM can lead to extensive disease and complication, especially in paediatric patients. © Ratna Dwi Restuti et al. |
Complication; Intraoperative findings; Pediatric dangerous CSOM |
abscess; adolescent; adult; Article; child; chronic suppurative otitis media; clinical article; clinical evaluation; facial nerve paralysis; female; hearing impairment; human; intraoperative period; male; middle ear surgery; retrospective study; secondary analysis; case report; chronic disease; facial nerve paralysis; fistula; middle ear; preschool child; suppurative otitis media; Adolescent; Child; Child, Preschool; Chronic Disease; Ear, Middle; Facial Paralysis; Fistula; Humans; Otitis Media, Suppurative; Retrospective Studies |
African Field Epidemiology Network |
19378688 |
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35018207 |
Article |
Q3 |
287 |
15281 |
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