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Riset dan Pengabdian Masyarakat Do Research Sosial Service and Innovation

Id	Authors	Author S Id	Title	Year	Source Title	Volume	Issue	Art No	Page Start	Page End	Cited By	Link	Affiliations	Authors With Affiliations	Abstract	Author Keywords	Index Keywords	Publisher	Issn	Pubmed Id	Document Type	Sjr Best Quartile	Sjr	Sjr Rank
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899	Tanto I.V., Dharma S., Juzar D.A., Bono A.A.H.	57221612652;55101301700;55358712500;57208146721;	Ventricular Septal Rupture Complicating an Acute ST-Segment Elevation Myocardial Infarction during the COVID-19 Pandemic	2021	International Journal of Angiology							https://www.scopus.com/inward/record.uri?eid=2-s2.0-85099596441&doi=10.1055%2fs-0040-1720971&partnerID=40&md5=aab866db219c647750534315d55f3fdf	Department of Cardiology and Vascular Medicine, Faculty of Medicine, University of Indonesia, Indonesian Cardiovascular Research Center, National Cardiovascular Center Harapan Kita, Jl S Parman Kav 87, Slipi, Jakarta Barat, Jakarta, 11420, Indonesia; Division of Cardiothoracic and Vascular Surgery, National Cardiovascular Center Harapan Kita, Jakarta, Indonesia	Tanto, I.V., Department of Cardiology and Vascular Medicine, Faculty of Medicine, University of Indonesia, Indonesian Cardiovascular Research Center, National Cardiovascular Center Harapan Kita, Jl S Parman Kav 87, Slipi, Jakarta Barat, Jakarta, 11420, Indonesia; Dharma, S., Department of Cardiology and Vascular Medicine, Faculty of Medicine, University of Indonesia, Indonesian Cardiovascular Research Center, National Cardiovascular Center Harapan Kita, Jl S Parman Kav 87, Slipi, Jakarta Barat, Jakarta, 11420, Indonesia; Juzar, D.A., Department of Cardiology and Vascular Medicine, Faculty of Medicine, University of Indonesia, Indonesian Cardiovascular Research Center, National Cardiovascular Center Harapan Kita, Jl S Parman Kav 87, Slipi, Jakarta Barat, Jakarta, 11420, Indonesia; Bono, A.A.H., Division of Cardiothoracic and Vascular Surgery, National Cardiovascular Center Harapan Kita, Jakarta, Indonesia	Ventricular septal rupture (VSR) is rare but a lethal complication of acute myocardial infarction (MI). Definite treatment requires the surgical closure of the VSR and coronary artery bypass grafting (CABG). However, the optimal timing for surgery is still controversial, particularly during the novel coronavirus disease 2019 (COVID-19) pandemic where medical procedures should be performed within the safest environment. Before surgery, a proper management in the intensive cardiovascular care unit is essential to maintain the stability of the hemodynamic profile related with VSR and determines the prognosis of the patient. We described a case of VSR complicating an anterior wall MI in a patient who admitted to our hospital during the COVID-19 pandemic that was treated successfully by surgical closure of the VSR and CABG. © 2021 BMJ Publishing Group. All rights reserved.	bypass grafting; myocardial infarction; surgical repair; ventricular septal rupture		Thieme Medical Publishers, Inc.	10611711		Article	Q3	293	15070	View
906	Utami T.W., Putri H.M.A.R., Hellyanti T.	57195720528;57221287879;57217993236;	High Frequency of Malignant Transformations on Ovarian Mature Teratomas at a Single University Hospital, Jakarta, Indonesia (2015–2018)	2021	Journal of Obstetrics and Gynecology of India							https://www.scopus.com/inward/record.uri?eid=2-s2.0-85098720629&doi=10.1007%2fs13224-020-01392-8&partnerID=40&md5=007db828cc36d3a44c192cdca5656bab	Faculty of Medicine, University of Indonesia, Jakarta, Indonesia; Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, Indonesia Army Hospital, Jakarta, Indonesia; Department of Pathological Anatomy, Cipto Mangunkusumo Hospital, Jakarta, Indonesia	Utami, T.W., Faculty of Medicine, University of Indonesia, Jakarta, Indonesia, Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Putri, H.M.A.R., Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, Indonesia Army Hospital, Jakarta, Indonesia; Hellyanti, T., Faculty of Medicine, University of Indonesia, Jakarta, Indonesia, Department of Pathological Anatomy, Cipto Mangunkusumo Hospital, Jakarta, Indonesia	[No abstract available]			Springer	09719202		Article	Q3	313	14416	View
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20	Kartika R.W., Alwi I., Yunir E., Waspadji S., Bardosono S., Immanuel S., Silalahi T., Sungkar S., Rachmat J., Suyatna F.D., Reksodiputro M.H.	57223447932;15055173800;36520254800;8678136400;21933841000;57272979000;56275255400;57016857300;6507225348;56039633100;35090488800;	A new innovation in topical diabetic foot ulcer; hyaluronic acid platelet-rich fibrin (HAPRF) gel - a study in inflammation and angiogenesis	2021	Bali Medical Journal	10	3		901	908		https://www.scopus.com/inward/record.uri?eid=2-s2.0-85123104761&doi=10.15562%2fbmj.v10i3.2317&partnerID=40&md5=60a98c7a6392eaa4cf35d6bc5c895812	Medical Science Faculty of Medicine, Universitas Indonesia, Indonesia; Department of Internal Medicine, Faculty of Medicine Universitas Indonesia-Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Department of Nutrition, Faculty of Medicine Universitas Indonesia, Jakarta, Indonesia; Department of Clinical Pathology, Faculty of Medicine Universitas Indonesia – Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Department of Internal Medicine, Krida Wacana Christian University, Jakarta, Indonesia; Department of Clinical Parasitology, Faculty of Medicine Universitas Indonesia, Jakarta, Indonesia; Department of Thoracic Cardiac and Vascular Surgery, Faculty of Medicine Universitas Indonesia, Jakarta, Indonesia; Department of Clinical Pharmacology, Faculty of Medicine Universitas Indonesia, Jakarta, Indonesia; Departement Facial Plastic Reconstructive Division, Department of Otorhinolaryngology, Faculty of Medicine, Universitas Indonesia, Cipto Mangunkusumo Hospital, Jakarta, Indonesia	Kartika, R.W., Medical Science Faculty of Medicine, Universitas Indonesia, Indonesia; Alwi, I., Department of Internal Medicine, Faculty of Medicine Universitas Indonesia-Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Yunir, E., Department of Internal Medicine, Faculty of Medicine Universitas Indonesia-Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Waspadji, S., Department of Internal Medicine, Faculty of Medicine Universitas Indonesia-Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Bardosono, S., Department of Nutrition, Faculty of Medicine Universitas Indonesia, Jakarta, Indonesia; Immanuel, S., Department of Clinical Pathology, Faculty of Medicine Universitas Indonesia – Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Silalahi, T., Department of Internal Medicine, Krida Wacana Christian University, Jakarta, Indonesia; Sungkar, S., Department of Clinical Parasitology, Faculty of Medicine Universitas Indonesia, Jakarta, Indonesia; Rachmat, J., Department of Thoracic Cardiac and Vascular Surgery, Faculty of Medicine Universitas Indonesia, Jakarta, Indonesia; Suyatna, F.D., Department of Clinical Pharmacology, Faculty of Medicine Universitas Indonesia, Jakarta, Indonesia; Reksodiputro, M.H., Departement Facial Plastic Reconstructive Division, Department of Otorhinolaryngology, Faculty of Medicine, Universitas Indonesia, Cipto Mangunkusumo Hospital, Jakarta, Indonesia	Background: Indonesia ranks 6th out of ten countries with the highest number of diabetes patients. An increase followed this condition in the prevalence of diabetic foot ulcers by around 15%. This study demonstrated the ability of combination of Platelet Rich Fibrin (PRF) and Hyaluronic Acid (HA) to reduce inflammation in diabetic foot ulcer (DFU) healing. Methods: In the baseline, all patients received the same treatment including wound debridement. There were 20 subjects divided into two groups; HAPRF and PRF. A part of sample was processed into lysate and stored in -80oC. The rest is applied as a topical therapy in DFU base on intervention. We analyzed the inflammation using two methods; swab in DFU and fibrin gel of HAPRF or PRF and ELISA on day-3 and day-7. We also measure the granulation index by digital photograph and analyze use ImageJ at the same time. Result: There were 20 diabetic patients with DFUs, performed analysis of IL-6 lysate gel HAPRF decrease significantly compare with PRF on day 3 (p= 0.038) and day-7 (p = 0.034). Granulation index evaluation, in HAPRF increase on day-3 (p = 0.043), day-7 (p = 0.049), and day-14 (p = 0.041). Conclusion: A-PRF +HA administration leads to reduce IL-6 levels, and accelerated wound healing of DFUs patients. HAPRF directly aids epithelialization and granulation index. © 2021, Sanglah General Hospital. All rights reserved.	Diabetic foot ulcer; Fibrin; Granulation index; Hyaluronic acid; Inflammation; Platelet		Sanglah General Hospital	20891180		Article	#N/A	#N/A	#N/A	View
29	Ariwicaksono S.T.C., Rahardjo H.E.	57212582959;37762030000;	The comparison of intravesical hyaluronic acid and other modalities for the improvement of interstitial cystitis symptoms: A systematic reviews and meta-analysis	2021	Bali Medical Journal	10	3		970	974		https://www.scopus.com/inward/record.uri?eid=2-s2.0-85121978362&doi=10.15562%2fbmj.v10i3.2510&partnerID=40&md5=0ddadc212b9221f4fe1b9ed43099c7b2	Department of Urology, Cipto Mangunkusumo National Hospital, Faculty of Medicine, Universitas Indonesia, Indonesia	Ariwicaksono, S.T.C., Department of Urology, Cipto Mangunkusumo National Hospital, Faculty of Medicine, Universitas Indonesia, Indonesia; Rahardjo, H.E., Department of Urology, Cipto Mangunkusumo National Hospital, Faculty of Medicine, Universitas Indonesia, Indonesia	Background: Interstitial cystitis (IC) is a chronic inflammation of the bladder which causes unpleasant sensations. This condition considerably reduces patients’ quality of life. Intravesical hyaluronic acid is one of the new interventions for interstitial cystitis management, in which a thorough review and meta-analysis regarding this topic are still limited. This study aimed to compare the efficacy of intravesical hyaluronic acid with other intravesical treatment modalities available to treat interstitial cystitis. Method: Systematic literature searching with the main keywords of “interstitial cystitis” or “bladder pain syndrome” and “intravesical hyaluronic acid” was conducted. The main outcome of this study was pain assessment using a visual analogue scale (VAS) and Interstitial Cystitis Symptoms Index (ICSI), and problem index (ICPI). Meta-analysis was carried out when comparative studies were available. Eleven studies were obtained to assess intravesical hyaluronic acid’s effects, including three in the meta-analysis. The intravesical treatments found as a comparison were heparin and chondroitin sulphate. Result: There was significant heterogeneity among studies included in all parameters. The pooled analysis showed no significant difference in VAS reduction, improvement of ICSI and ICPI score (p = 0.11, p = 0.35, and p = 0.28, respectively) between hyaluronic acid and other intravesical treatments. Conclusion: There was no significant difference between hyaluronic acid and other intravesical treatments. However, further research with a larger sample is needed to confirm the best modalities in interstitial cystitis. © 2021, Sanglah General Hospital. All rights reserved.	Hyaluronic acid; ICPI; ICSI; Interstitial cystitis; Pain; Symptoms; VAS		Sanglah General Hospital	20891180		Article	#N/A	#N/A	#N/A	View
30	Alinda M.D., Christopher P.M., Listiawan M.Y., Endaryanto A., Suroto H., Rantam F.A., Hendradi E., Notobroto H.B., Menaldi S.L.S.W., Prakoeswa C.R.S.	57202009260;57222755186;57202006621;55043187100;57148243900;6506692524;6507663471;56444366000;57192918198;57189894608;	Comparative efficacy of topical adipocyte-derived mesenchymal stem cells-conditioned medium (Admsc-cm) and amniotic membrane mesenchymal stem cells-conditioned medium (amsc-cm) on chronic plantar ulcers in leprosy: A randomized controlled trial	2021	Bali Medical Journal	10	3		958	963		https://www.scopus.com/inward/record.uri?eid=2-s2.0-85121976659&doi=10.15562%2fbmj.v10i3.2747&partnerID=40&md5=2cb312268e5b8b08565af75e187acace	Post Graduate Doctoral Program, Faculty of Medicine, Universitas Airlangga, East Java, Surabaya, Indonesia; Department of Dermatology and Venereology, Faculty of Medicine, Universitas Airlangga, Dr. Soetomo General Academic Hospital, East Java, Surabaya, Indonesia; Leprosy Study Group, Institute of Tropical Diseases, Universitas Airlangga, Surabaya, Indonesia; Universitas Airlangga Teaching Hospital, Surabaya, Indonesia; Faculty of Medicine, Universitas Pelita Harapan, Banten, Tangerang, Indonesia; Department of Pediatric, Faculty of Medicine, Universitas Airlangga, Dr. Soetomo General Academic Hospital, East Java, Surabaya, Indonesia; Cell and Tissue Bank, Faculty of Medicine, Universitas Airlangga, Dr. Soetomo General Academic Hospital, East Java, Surabaya, Indonesia; Department of Orthopaedic & Traumatology, Faculty of Medicine, Universitas Airlangga, Dr. Soetomo General Academic Hospital, East Java, Surabaya, Indonesia; Stem Cell Research and Development Center, Universitas Airlangga, East Java, Surabaya, Indonesia; Faculty of Pharmacy, Universitas Airlangga, East Java, Surabaya, Indonesia; Faculty of Public Health, Universitas Airlangga, East Java, Surabaya, Indonesia; Department of Dermatology and Venereology, Faculty of Medicine, Universitas Indonesia, Dr. Cipto Mangunkusumo National Central Public Hospital, Jakarta, Indonesia	Alinda, M.D., Post Graduate Doctoral Program, Faculty of Medicine, Universitas Airlangga, East Java, Surabaya, Indonesia, Department of Dermatology and Venereology, Faculty of Medicine, Universitas Airlangga, Dr. Soetomo General Academic Hospital, East Java, Surabaya, Indonesia, Leprosy Study Group, Institute of Tropical Diseases, Universitas Airlangga, Surabaya, Indonesia, Universitas Airlangga Teaching Hospital, Surabaya, Indonesia; Christopher, P.M., Faculty of Medicine, Universitas Pelita Harapan, Banten, Tangerang, Indonesia; Listiawan, M.Y., Department of Dermatology and Venereology, Faculty of Medicine, Universitas Airlangga, Dr. Soetomo General Academic Hospital, East Java, Surabaya, Indonesia, Leprosy Study Group, Institute of Tropical Diseases, Universitas Airlangga, Surabaya, Indonesia; Endaryanto, A., Department of Pediatric, Faculty of Medicine, Universitas Airlangga, Dr. Soetomo General Academic Hospital, East Java, Surabaya, Indonesia; Suroto, H., Cell and Tissue Bank, Faculty of Medicine, Universitas Airlangga, Dr. Soetomo General Academic Hospital, East Java, Surabaya, Indonesia, Department of Orthopaedic & Traumatology, Faculty of Medicine, Universitas Airlangga, Dr. Soetomo General Academic Hospital, East Java, Surabaya, Indonesia; Rantam, F.A., Stem Cell Research and Development Center, Universitas Airlangga, East Java, Surabaya, Indonesia; Hendradi, E., Faculty of Pharmacy, Universitas Airlangga, East Java, Surabaya, Indonesia; Notobroto, H.B., Faculty of Public Health, Universitas Airlangga, East Java, Surabaya, Indonesia; Menaldi, S.L.S.W., Department of Dermatology and Venereology, Faculty of Medicine, Universitas Indonesia, Dr. Cipto Mangunkusumo National Central Public Hospital, Jakarta, Indonesia; Prakoeswa, C.R.S., Department of Dermatology and Venereology, Faculty of Medicine, Universitas Airlangga, Dr. Soetomo General Academic Hospital, East Java, Surabaya, Indonesia, Leprosy Study Group, Institute of Tropical Diseases, Universitas Airlangga, Surabaya, Indonesia	Introduction: Chronic Plantar Ulcer of Leprosy (CPUL), one of the debilitating disabilities and complications, poses a treatment challenge. Utilization of stem cells, specifically adipocyte-derived mesenchymal stem cells-conditioned medium (ADMSC-CM) and amniotic membrane mesenchymal stem cells-conditioned medium (AMSC-CM), may serve as a novel therapeutic option. This study aims to compare the efficacy of topical ADMSC-CM, topical AMSC-CM, and farmazertin gauze dressing (FGD) only on the healing of CPUL. Methods: In this randomized controlled trial, our study recruited 54 subjects with CPUL. Subjects were randomly assigned to topical ADMSC-CM (n = 16), topical AMSC-CM (n = 22), or FGD (n = 16) applied every three days for up to 8 weeks. Data were analyzed using SPSS version 20 for Windows. Results: Healing percentage increased each week in all groups. Statistic differences between groups (p <0.05) were observed for ulcer mean size and depth reduction from week three onwards. No adverse reactions or complications were reported. At the end of the study, based on clinically improved ulcers, topical ADMSC-CM (100.0%) were superior in improving the healing of CPULs compared to topical AMSC-CM (54.55%) and FGD only (50.0%). Conclusion: ADMSC-CM and AMSC-CM are potential therapeutic agents in the management of CPUL, with ADMSC-CM being superior in overall ulcer improvement. © 2021, Sanglah General Hospital. All rights reserved.	ADMSC-CM; AMSC-CM; CPUL; Leprosy; Tropical Disease		Sanglah General Hospital	20891180		Article	#N/A	#N/A	#N/A	View
79	Saharman Y.R., Karuniawati A., Severin J.A., Verbrugh H.A.	55980934300;54886816200;8700385500;7103296623;	Infections and antimicrobial resistance in intensive care units in lower-middle income countries: a scoping review	2021	Antimicrobial Resistance and Infection Control	10	1	22			4	https://www.scopus.com/inward/record.uri?eid=2-s2.0-85100075262&doi=10.1186%2fs13756-020-00871-x&partnerID=40&md5=137569c4bc3b7584a1b51042515f7130	Department of Clinical Microbiology, Faculty of Medicine, Universitas Indonesia/Dr. Cipto Mangunkusumo General Hospital, Jakarta, Indonesia; Department of Medical Microbiology and Infectious Diseases, Erasmus MC University Medical Center Rotterdam, Dr. Molewaterplein 40, Rotterdam, 3015 GD, Netherlands	Saharman, Y.R., Department of Clinical Microbiology, Faculty of Medicine, Universitas Indonesia/Dr. Cipto Mangunkusumo General Hospital, Jakarta, Indonesia, Department of Medical Microbiology and Infectious Diseases, Erasmus MC University Medical Center Rotterdam, Dr. Molewaterplein 40, Rotterdam, 3015 GD, Netherlands; Karuniawati, A., Department of Clinical Microbiology, Faculty of Medicine, Universitas Indonesia/Dr. Cipto Mangunkusumo General Hospital, Jakarta, Indonesia; Severin, J.A., Department of Medical Microbiology and Infectious Diseases, Erasmus MC University Medical Center Rotterdam, Dr. Molewaterplein 40, Rotterdam, 3015 GD, Netherlands; Verbrugh, H.A., Department of Medical Microbiology and Infectious Diseases, Erasmus MC University Medical Center Rotterdam, Dr. Molewaterplein 40, Rotterdam, 3015 GD, Netherlands	Background: Intensive care units (ICUs) in lower-middle income countries (LMICs) are suspected to constitute a special risk for patients of acquiring infection due to multiple antibiotic resistant organisms. The aim of this systematic scoping review was to present the data published on ICU-acquired infections and on antimicrobial resistance observed in ICUs in LMICs over a 13-year period. A systematic scoping review was conducted according to the PRISMA extension guideline for scoping reviews and registered in the Open Science Framework. Main body of the abstract: Articles were sought that reported on ICU-acquired infection in LMICs between 2005 and 2018. Two reviewers parallelly reviewed 1961 titles and abstracts retrieved from five data banks, found 274 eligible and finally included 51. Most LMICs had not produced reports in Q1 or Q2 journals in this period, constituting a large gap in knowledge. However, from the reported evidence it is clear that the rate of ICU-acquired infections was comparable, albeit approximately 10% higher, in LMICs compared to high income countries. In contrast, ICU mortality was much higher in LMICs (33.6%) than in high income countries (< 20%). Multidrug-resistant Gram-negative species, especially Acinetobacter baumannii and Pseudomonas aeruginosa, and Klebsiella pneumoniae played a much more dominant role in LMIC ICUs than in those in high income countries. However, interventions to improve this situation have been shown to be feasible and effective, even cost-effective. Conclusions: Compared to high income countries the burden of ICU-acquired infection is higher in LMICs, as is the level of antimicrobial resistance; the pathogen distribution is also different. However, there is evidence that interventions are feasible and may be quite effective in these settings. Protocol Registration The protocol was registered with Open Science Framework (https://osf.io/c8vjk) © 2021, The Author(s).	Acinetobacter; Bacterial drug resistance; Cross infection; Infection control; Intensive care units	antibiotic agent; Acinetobacter baumannii; adult; antibiotic resistance; bacterial infection; cross infection; female; high income country; hospital mortality; human; infection control; intensive care unit; Klebsiella pneumoniae; major clinical study; male; middle income country; multidrug resistance; nonhuman; priority journal; Pseudomonas aeruginosa; Review; bacterial infection; cross infection; developing country; Acinetobacter baumannii; Adult; Bacterial Infections; Cross Infection; Developing Countries; Drug Resistance, Bacterial; Humans; Intensive Care Units; Klebsiella pneumoniae; Pseudomonas aeruginosa	BioMed Central Ltd	20472994	33514432	Review	Q1	1456	2381	View
139	Harzif A., Anggraeni T., Syaharutsa D., Hellyanti T.	57191493435;57192894826;57204145265;57217993236;	Hysteroscopy role for female genital tuberculosis	2021	Gynecology and Minimally Invasive Therapy	10	4		243	246		https://www.scopus.com/inward/record.uri?eid=2-s2.0-85119285063&doi=10.4103%2fGMIT.GMIT_151_20&partnerID=40&md5=2dea6cbfe3f4a65bb9bc6b632d3cc573	Department of Obstetrics and Gynecology, Faculty of Medicine, University of Indonesia, Cipto Mangunkusumo General Hospital, Jakarta, Indonesia; Department of Anatomical Pathology, Faculty of Medicine, University of Indonesia, Cipto Mangunkusumo General Hospital, Jakarta, Indonesia	Harzif, A., Department of Obstetrics and Gynecology, Faculty of Medicine, University of Indonesia, Cipto Mangunkusumo General Hospital, Jakarta, Indonesia; Anggraeni, T., Department of Obstetrics and Gynecology, Faculty of Medicine, University of Indonesia, Cipto Mangunkusumo General Hospital, Jakarta, Indonesia; Syaharutsa, D., Department of Obstetrics and Gynecology, Faculty of Medicine, University of Indonesia, Cipto Mangunkusumo General Hospital, Jakarta, Indonesia; Hellyanti, T., Department of Anatomical Pathology, Faculty of Medicine, University of Indonesia, Cipto Mangunkusumo General Hospital, Jakarta, Indonesia	Female genital tuberculosis affects the quality of women's lives. One of the symptoms is amenorrhea. In our country, it is still underdiagnosed due to limited resources. Hysteroscopy is known as one of the diagnostic tools for this condition. We performed hysteroscopy and endometrial biopsy in four cases. Hysteroscopy findings show various signs. Histopathological examination showed typical features of tuberculosis in some cases. We also learned that hysteroscopy could evaluate the condition of the endometrium when ongoing and after treatment is accomplished. It is useful for further explanation to the client. Hysteroscopy can be utilized as a diagnostic tool for endometrial sampling, evaluate intracavity condition after treatment, and prognostic tool for future reproductive function. © 2021 Wolters Kluwer Medknow Publications. All rights reserved.	Amenorrhea; caseous necrosis; genital tuberculosis; hysteroscopy	tuberculostatic agent; adolescent; adult; Article; case report; caseation; chronic inflammation; clinical article; clinical feature; diagnostic value; echography; endometritis; endometrium; endometrium biopsy; female; female genital tuberculosis; granulomatous inflammation; histopathology; human; human tissue; hysteroscopy; laparotomy; primary amenorrhea; secondary amenorrhea; sister; tuberculous peritonitis; tuberculous spondylitis	Wolters Kluwer Medknow Publications	22133070		Article	Q3	441	11202	View
215	Dilogo I.H., Aditianingsih D., Sugiarto A., Burhan E., Damayanti T., Sitompul P.A., Mariana N., Antarianto R.D., Liem I.K., Kispa T., Mujadid F., Novialdi N., Luviah E., Kurniawati T., Lubis A.M.T., Rahmatika D.	56161962800;56312263600;57189612291;36058554600;36058523500;57224505288;57194732286;57190862806;55802927800;56515348000;57204398571;57224555404;56114966200;55213290600;15122639800;57474077600;	Umbilical cord mesenchymal stromal cells as critical COVID-19 adjuvant therapy: A randomized controlled trial	2021	Stem Cells Translational Medicine	10	9		1279	1287	8	https://www.scopus.com/inward/record.uri?eid=2-s2.0-85107732762&doi=10.1002%2fsctm.21-0046&partnerID=40&md5=197659d90f645ca5130e69fcf16b7b4d	Stem Cell Medical Technology Integrated Service Unit, Cipto Mangunkusumo Central Hospital, Faculty of Medicine Universitas Indonesia, Jakarta, Indonesia; Stem Cell and Tissue Engineering Research Cluster Indonesian Medical Education and Research Institute (IMERI) Universitas Indonesia, Jakarta, Indonesia; Department of Orthopaedic and Traumatology, Cipto Mangunkusumo General Hospital, Faculty of Medicine Universitas Indonesia, Jakarta, Indonesia; Department of Anesthesiology and Intensive Care Universitas Indonesia, Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Intensive Care Division, Universitas Indonesia Hospital, Depok, Indonesia; Department of Pulmonology and Respiratory Medicine, Faculty of Medicine Universitas Indonesia, Persahabatan General Hospital, Jakarta, Indonesia; Directorate of Medical Services, Nursing and Supporting, Sulianti Saroso Infection Disease Hospital, Jakarta, Indonesia; Directorate of Human Resources Development, Education and Operational Sulianti Saroso Infection Disease Hospital, Jakarta, Indonesia; Department of Histology, Universitas Indonesia Fakultas Kedokteran, Jakarta, Indonesia; Department of Anatomy, Universitas Indonesia Fakultas Kedokteran, Jakarta, Indonesia; Installation of Innovation Management and Intellectual Property, Cipto Mangunkusumo Hospital, Jakarta, Indonesia	Dilogo, I.H., Stem Cell Medical Technology Integrated Service Unit, Cipto Mangunkusumo Central Hospital, Faculty of Medicine Universitas Indonesia, Jakarta, Indonesia, Stem Cell and Tissue Engineering Research Cluster Indonesian Medical Education and Research Institute (IMERI) Universitas Indonesia, Jakarta, Indonesia, Department of Orthopaedic and Traumatology, Cipto Mangunkusumo General Hospital, Faculty of Medicine Universitas Indonesia, Jakarta, Indonesia; Aditianingsih, D., Department of Anesthesiology and Intensive Care Universitas Indonesia, Cipto Mangunkusumo Hospital, Jakarta, Indonesia, Intensive Care Division, Universitas Indonesia Hospital, Depok, Indonesia; Sugiarto, A., Department of Anesthesiology and Intensive Care Universitas Indonesia, Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Burhan, E., Department of Pulmonology and Respiratory Medicine, Faculty of Medicine Universitas Indonesia, Persahabatan General Hospital, Jakarta, Indonesia; Damayanti, T., Department of Pulmonology and Respiratory Medicine, Faculty of Medicine Universitas Indonesia, Persahabatan General Hospital, Jakarta, Indonesia; Sitompul, P.A., Directorate of Medical Services, Nursing and Supporting, Sulianti Saroso Infection Disease Hospital, Jakarta, Indonesia; Mariana, N., Directorate of Human Resources Development, Education and Operational Sulianti Saroso Infection Disease Hospital, Jakarta, Indonesia; Antarianto, R.D., Stem Cell and Tissue Engineering Research Cluster Indonesian Medical Education and Research Institute (IMERI) Universitas Indonesia, Jakarta, Indonesia, Department of Histology, Universitas Indonesia Fakultas Kedokteran, Jakarta, Indonesia; Liem, I.K., Stem Cell Medical Technology Integrated Service Unit, Cipto Mangunkusumo Central Hospital, Faculty of Medicine Universitas Indonesia, Jakarta, Indonesia, Stem Cell and Tissue Engineering Research Cluster Indonesian Medical Education and Research Institute (IMERI) Universitas Indonesia, Jakarta, Indonesia, Department of Anatomy, Universitas Indonesia Fakultas Kedokteran, Jakarta, Indonesia; Kispa, T., Stem Cell Medical Technology Integrated Service Unit, Cipto Mangunkusumo Central Hospital, Faculty of Medicine Universitas Indonesia, Jakarta, Indonesia; Mujadid, F., Stem Cell Medical Technology Integrated Service Unit, Cipto Mangunkusumo Central Hospital, Faculty of Medicine Universitas Indonesia, Jakarta, Indonesia; Novialdi, N., Stem Cell Medical Technology Integrated Service Unit, Cipto Mangunkusumo Central Hospital, Faculty of Medicine Universitas Indonesia, Jakarta, Indonesia; Luviah, E., Stem Cell and Tissue Engineering Research Cluster Indonesian Medical Education and Research Institute (IMERI) Universitas Indonesia, Jakarta, Indonesia; Kurniawati, T., Stem Cell Medical Technology Integrated Service Unit, Cipto Mangunkusumo Central Hospital, Faculty of Medicine Universitas Indonesia, Jakarta, Indonesia; Lubis, A.M.T., Department of Orthopaedic and Traumatology, Cipto Mangunkusumo General Hospital, Faculty of Medicine Universitas Indonesia, Jakarta, Indonesia, Installation of Innovation Management and Intellectual Property, Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Rahmatika, D., Stem Cell Medical Technology Integrated Service Unit, Cipto Mangunkusumo Central Hospital, Faculty of Medicine Universitas Indonesia, Jakarta, Indonesia	One of the main causes of acute respiratory distress syndrome in coronavirus disease 2019 (COVID-19) is cytokine storm, although the exact cause is still unknown. Umbilical cord mesenchymal stromal cells (UC-MSCs) influence proinflammatory T-helper 2 (Th2) cells to shift to an anti-inflammatory agent. To investigate efficacy of UC-MSC administration as adjuvant therapy in critically ill patients with COVID-19, we conducted a double-blind, multicentered, randomized controlled trial at four COVID-19 referral hospitals in Jakarta, Indonesia. This study included 40 randomly allocated critically ill patients with COVID-19; 20 patients received an intravenous infusion of 1 × 106/kg body weight UC-MSCs in 100 ml saline (0.9%) solution (SS) and 20 patients received 100 ml 0.9% SS as the control group. All patients received standard therapy. The primary outcome was measured by survival rate and/or length of ventilator usage. The secondary outcome was measured by clinical and laboratory improvement, with serious adverse events. Our study showed the survival rate in the UC-MSCs group was 2.5 times higher than that in the control group (P =.047), which is 10 patients and 4 patients in the UC-MSCs and control groups, respectively. In patients with comorbidities, UC-MSC administration increased the survival rate by 4.5 times compared with controls. The length of stay in the intensive care unit and ventilator usage were not statistically significant, and no adverse events were reported. The application of infusion UC-MSCs significantly decreased interleukin 6 in the recovered patients (P =.023). Therefore, application of intravenous UC-MSCs as adjuvant treatment for critically ill patients with COVID-19 increases the survival rate by modulating the immune system toward an anti-inflammatory state. © 2021 The Authors. STEM CELLS TRANSLATIONAL MEDICINE published by Wiley Periodicals LLC on behalf of AlphaMed Press.	adjuvants; cord stem cell transplantation; COVID-19; cytokine release syndrome; immunology; mesenchymal stromal cells	5' nucleotidase; azithromycin; C reactive protein; CD34 antigen; CD4 antigen; CD56 antigen; CD8 antigen; chemokine receptor CXCR3; D dimer; ferritin; fibrinogen; hemoglobin; interleukin 10; interleukin 6; lactic acid; leukemia inhibitory factor; oseltamivir; procalcitonin; Thy 1 membrane glycoprotein; vasculotropin; adjuvant therapy; adult; adult respiratory distress syndrome; Article; artificial ventilation; blood cell count; clinical article; clinical decision making; computer assisted tomography; controlled study; coronavirus disease 2019; critically ill patient; cytokine release syndrome; cytokine storm; double blind procedure; female; flow cytometry; fluid resuscitation; ground glass opacity; hematocrit; Horowitz index; human; hypotension; intensive care unit; length of stay; leukopen	John Wiley and Sons Ltd	21576564	34102020	Article	Q1	1781	1654	View
246	Ichwan S., Ningsih H.L., Aman R.A., Tandian D., Ashari S., Gunawan K., Nugroho S.W.	57192906639;57226696258;36848942500;57192891173;57195942105;57195935319;57460519700;	O6-methylguanine-dna methyltransferase (Mgmt) promoter methylation status of high-grade and low-grade gliomas	2021	Bali Medical Journal	10	2		644	647		https://www.scopus.com/inward/record.uri?eid=2-s2.0-85112380308&doi=10.15562%2fbmj.v10i2.2316&partnerID=40&md5=c8e8a17690a11b9cc2f1729ff7a40de8	Department of Neurosurgery, Faculty of Medicine, Universitas Indonesia, Cipto Mangunkusumo National General Hospital, Jakarta, Indonesia	Ichwan, S., Department of Neurosurgery, Faculty of Medicine, Universitas Indonesia, Cipto Mangunkusumo National General Hospital, Jakarta, Indonesia; Ningsih, H.L., Department of Neurosurgery, Faculty of Medicine, Universitas Indonesia, Cipto Mangunkusumo National General Hospital, Jakarta, Indonesia; Aman, R.A., Department of Neurosurgery, Faculty of Medicine, Universitas Indonesia, Cipto Mangunkusumo National General Hospital, Jakarta, Indonesia; Tandian, D., Department of Neurosurgery, Faculty of Medicine, Universitas Indonesia, Cipto Mangunkusumo National General Hospital, Jakarta, Indonesia; Ashari, S., Department of Neurosurgery, Faculty of Medicine, Universitas Indonesia, Cipto Mangunkusumo National General Hospital, Jakarta, Indonesia; Gunawan, K., Department of Neurosurgery, Faculty of Medicine, Universitas Indonesia, Cipto Mangunkusumo National General Hospital, Jakarta, Indonesia; Nugroho, S.W., Department of Neurosurgery, Faculty of Medicine, Universitas Indonesia, Cipto Mangunkusumo National General Hospital, Jakarta, Indonesia	Background: O6-methylguanine-DNA methyltransferase (MGMT) is a DNA-repair enzyme that correlates with tumor resistance mechanism to chemotherapy. Methylation of the MGMT promoter inhibits the cells from producing MGMT and is useful to predict chemotherapy’s effectiveness with alkylating agents. This study aims to evaluate the MGMT promoter methylation of low-grade and high-grade glioma in the Neurosurgery Department of Cipto Mangunkusumo National General Hospital. Methods: We evaluated MGMT promoter methylation status using methylation-specific polymerase chain reaction in low and high-grade glioma patients who underwent surgical resection in the Neurosurgery Department of Cipto Mangunkusomo Hospital Jakarta. The result then correlated with age, sex, Karnofsky Performance Scale (KPS), and glioma grading. Data were analyzed using SPSS version 20 for Windows. Results: MGMT promoter methylation was observed more often in patients diagnosed with age more than 40 years old than in patients less than 40 years old (85.7% vs. 50.0%), also more in men than women (77.7% vs. 50.0%). In patients with KPS more than 70 and KPS 70 or less, methylation of MGMT promoter was observed in 70.0% and 57.1%, respectively. Based on tumor grading, MGMT promoter methylation was observed more often in low-grade gliomas (WHO grade II) than high-grade gliomas (WHO grade II and IV) (85.7% vs. 50.0%). There was no significant relationship between gender, age, KPS, malignancy degree, and Overall Survival (OS) to the MGMT promoter methylation (p>0.05). Conclusion: MGMT promoter methylation was observed less in the higher grade of tumors (grade IV), lower KPS, younger age at the time of diagnosis, and female patients, although the differences were not statistically significant. MGMT promoter methylation was observed more often in gliomas with oligodendroglioma components. © 2021, Sanglah General Hospital. All rights reserved.	High-grade glioma; Low-grade glioma; Methylation; MGMT; Promoter		Sanglah General Hospital	20891180		Article	#N/A	#N/A	#N/A	View
247	Isa M.M., Thayeb A., Meildi M., Hutagalung M.B.Z.	57218775163;57219243978;57226686555;57210153230;	Complete tubular duplication of colon presenting as rectovestibular fistula: A case report	2021	Bali Medical Journal	10	2		526	528		https://www.scopus.com/inward/record.uri?eid=2-s2.0-85112379837&doi=10.15562%2fbmj.v10i2.2386&partnerID=40&md5=d43bedd4e25f7ac4c1c60fafddc9df64	Pediatric Surgery Division, Department of Surgery, Faculty of Medicine, Universitas Syiah Kuala/Dr. Zainoel Abidin Hospital, Banda Aceh, Indonesia; Pediatric Surgery Division, Department of Surgery, Faculty of Medicine, Universitas Indonesia/Dr. Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Department of Surgery, Faculty of Medicine, Universitas Syiah Kuala/Dr. Zainoel Abidin Hospital, Banda Aceh, Indonesia	Isa, M.M., Pediatric Surgery Division, Department of Surgery, Faculty of Medicine, Universitas Syiah Kuala/Dr. Zainoel Abidin Hospital, Banda Aceh, Indonesia; Thayeb, A., Pediatric Surgery Division, Department of Surgery, Faculty of Medicine, Universitas Indonesia/Dr. Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Meildi, M., Department of Surgery, Faculty of Medicine, Universitas Syiah Kuala/Dr. Zainoel Abidin Hospital, Banda Aceh, Indonesia; Hutagalung, M.B.Z., Department of Surgery, Faculty of Medicine, Universitas Syiah Kuala/Dr. Zainoel Abidin Hospital, Banda Aceh, Indonesia	Background: Duplication of the gastrointestinal tract is a rare congenital disorder in pediatric patients. Complete resection in case of a total tubular duplication that requires total or subtotal colectomy is undesirable in children. Case Presentation: This case presented a simple surgical technique for treating complete colonic duplication without colonic resection. A 2 months old female baby with abdominal distention and stool complaint came out from her vaginal vestibular and normal anus. A digital rectal exam showed a palpable mass in the posterior region. Abdominal CT Scan showed a rounded mass with size 2x2 cm in the left posterolateral of rectum region. The initial diagnosis was suspected sacrococcygeal tumor type 4 with rectovestibular fistula. Intraoperative findings showed duplication of the caecum, appendix, total colon (ascending to sigmoid) and rectum (one directed to the vagina and the other to anus). The ileostomy was done 20 cm from the ileocaecal junction as a temporary treatment to relieving distention with definitive repair planned in the following months. The second stage repair was performed after 1-year-old with posterosagital anorectoplasty followed by distal separation of the duplicated colon using a 12 cm linear stapler. For this case, the third stage repair was done one year after the previous surgery to close the remaining ileostomy. The patient’s outcome showed good results with normal defecating function and no complication. Conclusion: Complete tubular duplication is a rare case without specific clinical symptoms, but the assessment of the diagnosis can be assisted by radiology such as abdominal CT and barium enema. We hope this article could illustrate management for complete tubular duplication of colon presenting as rectovestibular fistula, thus reflect how important clinical judgment and initial diagnostic in our health care system. © 2021, Sanglah General Hospital. All rights reserved.	Colon Duplication; Repair; Surgery		Sanglah General Hospital	20891180		Article	#N/A	#N/A	#N/A	View

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