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Riset dan Pengabdian Masyarakat Do Research Sosial Service and Innovation

Id	Authors	Author S Id	Title	Year	Source Title	Volume	Art No	Cited By	Link	Affiliations	Authors With Affiliations	Abstract	Author Keywords	Publisher	Issn	Isbn	Document Type	Sjr Best Quartile	Sjr	Sjr Rank
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501	Sutanto R.L., Purwaningsih E.H., Krisnamurti D.G.B.	57222060277;57186723500;55934951600;	Antiaging effects of Acalypha indica L. extract administration on tumor necrosis factor-a (TNF-a) protein level in major organs of aged Sprague-Dawley rats	2021	AIP Conference Proceedings	2344	040011		https://www.scopus.com/inward/record.uri?eid=2-s2.0-85103498448&doi=10.1063%2f5.0048267&partnerID=40&md5=0c80797e53b938c80ec492fb2905bba1	Undergraduate Student, Faculty of Medicine, Universitas Indonesia, Jl. Salemba Raya No. 6, Central Jakarta, DKI Jakarta, 10430, Indonesia; Department of Medical Pharmacy, Faculty of Medicine, Universitas Indonesia, Jl. Salemba Raya No. 6, Central Jakarta, DKI Jakarta, 10430, Indonesia; Drug Development Research Cluster, Indonesia Medical Education and Research Institute (IMERI), Faculty of Medicine, Universitas Indonesia, Jl. Salemba Raya No. 6, Central Jakarta, DKI Jakarta, 10430, Indonesia	Sutanto, R.L., Undergraduate Student, Faculty of Medicine, Universitas Indonesia, Jl. Salemba Raya No. 6, Central Jakarta, DKI Jakarta, 10430, Indonesia; Purwaningsih, E.H., Department of Medical Pharmacy, Faculty of Medicine, Universitas Indonesia, Jl. Salemba Raya No. 6, Central Jakarta, DKI Jakarta, 10430, Indonesia, Drug Development Research Cluster, Indonesia Medical Education and Research Institute (IMERI), Faculty of Medicine, Universitas Indonesia, Jl. Salemba Raya No. 6, Central Jakarta, DKI Jakarta, 10430, Indonesia; Krisnamurti, D.G.B., Department of Medical Pharmacy, Faculty of Medicine, Universitas Indonesia, Jl. Salemba Raya No. 6, Central Jakarta, DKI Jakarta, 10430, Indonesia, Drug Development Research Cluster, Indonesia Medical Education and Research Institute (IMERI), Faculty of Medicine, Universitas Indonesia, Jl. Salemba Raya No. 6, Central Jakarta, DKI Jakarta, 10430, Indonesia	Non-communicable diseases, such as cardiovascular diseases or kidney dysfunctions, tend to have expensive and unavailable treatments. This fact, coupled with the rising trend of such diseases, means that priority should be given towards preventive measures. One such measure is the administration of antioxidants to counter the increasing inflammatory markers, such as TNF-a, in the pathogenesis of chronic non-communicable diseases. However, the usage of synthetic antioxidants chronically may incur side effects and expensive. Indonesia is home to diverse sorts of vegetations as an agricultural power, such as Acalypha indica L. (AI). AI has been used empirically by cultures across the globe and is found to have antioxidant properties. This study was conducted on aged Sprague-Dawley rats. Rats were divided into four groups, the negative control (placebo), positive control using 6 IU vitamin E, treatment group using 250 mg/kg of body weight (mg/kg BW) AI extract, and control using young rats. The rats were then terminated after 28 days, and the major organs, kidneys, and hearts were examined using ELISA to look for TNF-a concentration. Data collected were analyzed using Saphiro-Wilk test and one-way ANOVA. AI administration yielded a decrease of TNF-a in both the kidneys (0.95 ± 0.76 pg/mg in the treatment group vs. 1.37 ± 0.41 pg/mg in the negative control) and hearts (15.43 pg/mg ± 2.33 in the treatment group vs. 16.50 ± 1.33 pg/mg in the negative control), of aged SD rats, albeit insignificantly. A relatively short time of treatment in this study could be attributed to the insignificant decrease in kidney and cardiac tissue. Nevertheless, this finding of decreased TNF-a suggests a potential anti-inflammatory and antiaging effect of AI. Further research suggestions on the investigation of AI are using longer time of treatment and other test subjects. © 2021 Author(s).	Acalypha indica; Aging; heart; kidney; TNF-a	American Institute of Physics Inc.	0094243X	9780735440869	Conference Paper	-	177	20880	View
502	Zakaria H., Setiawan R., Mayza A.	24465810100;57210969274;57211585788;	Analysis of quantitative EEG (QEEG) parameters on post-stroke patients undergoing static bicycle and mirror combination therapy	2021	AIP Conference Proceedings	2344	050006		https://www.scopus.com/inward/record.uri?eid=2-s2.0-85103495833&doi=10.1063%2f5.0047217&partnerID=40&md5=194ec9233261b2f6297da53ee96182d2	School of Electrical Engineering and Informatics, Bandung Institute of Technology (ITB), Ganesa 10, Bandung, West Java, 40119, Indonesia; Neurology Department and Cluster of Medical Technology IMERI, Faculty of Medicine, Universitas Indonesia, Jl. Salemba Raya No 6, Central Jakarta, 10430, Indonesia	Zakaria, H., School of Electrical Engineering and Informatics, Bandung Institute of Technology (ITB), Ganesa 10, Bandung, West Java, 40119, Indonesia; Setiawan, R., School of Electrical Engineering and Informatics, Bandung Institute of Technology (ITB), Ganesa 10, Bandung, West Java, 40119, Indonesia; Mayza, A., School of Electrical Engineering and Informatics, Bandung Institute of Technology (ITB), Ganesa 10, Bandung, West Java, 40119, Indonesia, Neurology Department and Cluster of Medical Technology IMERI, Faculty of Medicine, Universitas Indonesia, Jl. Salemba Raya No 6, Central Jakarta, 10430, Indonesia	Stroke causes neurological disorders such as reduced muscle motor skills, as well as cognitive, visual, and coordination functions, significantly. The reduced level of independence and mobility of a person can affect their quality of life. Previous research used static bicycles or mirrors for stroke therapy. This work combined both static bicycle and mirror therapy for post-stroke patients. This study aimed to find quantitative EEG parameters that can be used to characterize neurological change. The expected decrease in the average relative power of delta and theta then increased alpha and beta. Twelve post-stroke patients and twelve healthy subjects were given 2 tasks: imaginary (motor imagery) and action (motor execution). The electrodes were placed on 8 points with 10-20 localization principle rules. Data were analyzed and tested using linear regression and paired t. The result showed that static bicycle and mirror combination therapy affects a subject group of right stroke patients than a subject group of left stroke patients. When given imaginary session (motor imagery), in relative power of delta-band frequency of right stroke patients decreased by -18.65 ± 4.9% (p = 0.0001) and action session (motor execution) by -11.23 ± 6.1% (p = 0.0035), while average relative power of theta frequency band only decreased significantly by -6.03 ± 6.4% (p = 0.0429) an imaginary session. Then, this therapy also succeeded in enhancement relative power of alpha frequency band when given imaginary session, i.e 5.45 ± 4.2% (p = 0.0161) and action session, i.e 6.92 ± 4.6% (p = 0.0024). Furthermore, the relative power of the beta frequency band also increased when given an imaginary session by 19.23 ± 9.1% (p = 0.0026) and action session by 7.29 ± 7.5% (p = 0.0194). In conclusion, relative power, amplitude, and time (latency) of P300 and C3 to C4 ratio indicated improved health data, especially for right stroke patient subjects during therapy. © 2021 Author(s).	Combination Therapy; Mirror; Post-Stroke Patients; QEEG; Static Bicycle	American Institute of Physics Inc.	0094243X	9780735440869	Conference Paper	-	177	20880	View
503	Putri N.M., Kreshanti P., Tunjung N., Indania A., Basuki A., Sukasah C.L.	57192904294;36192866200;57208446370;57195935195;57201667022;57218391534;	Efficacy of honey dressing versus hydrogel dressing for wound healing	2021	AIP Conference Proceedings	2344	020022	1	https://www.scopus.com/inward/record.uri?eid=2-s2.0-85103495468&doi=10.1063%2f5.0047363&partnerID=40&md5=961e15f5dfacb7b7506f8a12294a1104	Plastic and Reconstructive Division, Department of Surgery, Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Research Center for Biomedical Engineering, Faculty of Engineering, Universitas Indonesia, Kampus Baru UI, Depok, West-Java, 16424, Indonesia; Plastic and Reconstructive Division, Department of Surgery, Faculty of Medicine, Universitas Indonesia, Jl. Salemba Raya No. 6, Central Jakarta, DKI Jakarta, 10430, Indonesia	Putri, N.M., Plastic and Reconstructive Division, Department of Surgery, Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Kreshanti, P., Plastic and Reconstructive Division, Department of Surgery, Cipto Mangunkusumo Hospital, Jakarta, Indonesia, Research Center for Biomedical Engineering, Faculty of Engineering, Universitas Indonesia, Kampus Baru UI, Depok, West-Java, 16424, Indonesia; Tunjung, N., Plastic and Reconstructive Division, Department of Surgery, Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Indania, A., Plastic and Reconstructive Division, Department of Surgery, Faculty of Medicine, Universitas Indonesia, Jl. Salemba Raya No. 6, Central Jakarta, DKI Jakarta, 10430, Indonesia; Basuki, A., Plastic and Reconstructive Division, Department of Surgery, Faculty of Medicine, Universitas Indonesia, Jl. Salemba Raya No. 6, Central Jakarta, DKI Jakarta, 10430, Indonesia; Sukasah, C.L., Plastic and Reconstructive Division, Department of Surgery, Cipto Mangunkusumo Hospital, Jakarta, Indonesia	Background: The field of plastic surgery involves wounds, such as acute and chronic or non-healing wounds. The mortality and morbidity inflicted by wounds may be substantial. To enhance wound healing and decrease morbidity and mortality, wound dressing selection is critical. Hydrogel dressing is a modern dressing that is versatile for various clinical situations. Nevertheless, a hydrogel may be expensive and not always readily available. Since the Egyptian period, honey has been used as a dressing, which was suggested to have an antimicrobial, anti-inflammatory, and immunomodulatory effect. Aim: To compare hydrogel and honey as dressing for all types of wounds in terms of wound healing time and slough production. Method: We conducted literature searching in multiple online databases using the keywords "wound", "honey"or "honey dressing", "hydrogel"or "hydrogel dressing", "healing time", and "slough"or "necrotic tissue". Key terms were combined using Boolean operators and also searched using Medical Subheading (MeSH terms). Literature searches were conducted in the following databases; ProQuest, MEDLINE, Ebsco, EMBASE, Cochrane, Scopus, and Science Direct for randomized-controlled trial studies. Results: Literature searching yielded two randomized-controlled trials. Critical appraisal revealed that both studies were deemed valid. Honey dressing were similar to hydrogel dressing in terms of healing time 30.3 ± 6.7 (7-58) days vs. 33.2 ± 5.4 (14-61) days; 16.08 (12.3-19.9) days vs 17.12 (11.7-22.5) days; 17.13 (13.1-21.1) days vs 16.53 (12.3-20.8) days, respectively. However, Honey group has a slightly higher risk of slough production with an absolute risk increase of 4% for the non-HIV group and 3% for the combined group (HIV and non-HIV). Conclusion: The efficacy of honey as a wound dressing is equivalent to hydrogel for treating wounds in terms of wound healing duration. Nevertheless, the risk of slough production is slightly higher in the honey group. © 2021 Author(s).	Acute wound; chronic wound; healing time; honey dressing; hydrogel dressing	American Institute of Physics Inc.	0094243X	9780735440869	Conference Paper	-	177	20880	View
504	Adawiyah R., Alhaq A.H., Mandala D.K., Sahlan M., Pratami D.K., Farida S.	57208658742;57222626933;57216338830;57189182661;57200370046;57193707159;	The effectivity of Indonesian propolis from Tetragonula biroi bee as an antifungal agent for Candida sp. And Cryptococcus neoformans	2021	AIP Conference Proceedings	2344	040013		https://www.scopus.com/inward/record.uri?eid=2-s2.0-85103494652&doi=10.1063%2f5.0047205&partnerID=40&md5=38e06697e888ef36f79129d52eb047f1	Department of Parasitology, Faculty of Medicine, Universitas Indonesia, Jakarta, 10430, Indonesia; Study Program of Clinical Parasitology, Faculty of Medicine, Universitas Indonesia, Jakarta, 10430, Indonesia; Research Center for Biomedical Engineering, Faculty of Engineering, Universitas Indonesia, Depok, West Java, 16424, Indonesia; Undergraduate Programm, Faculty of Medicine, Universitas Indonesia, Jakarta, 10430, Indonesia; Department of Chemical Engineering, Faculty of Engineering, Universitas Indonesia, Depok, West Java, 16424, Indonesia; Lab of Pharmacognosy and Phytochemistry, Faculty of Pharmacy, Pancasila University, Jakarta, 12640, Indonesia; Department of Pharmacy, Faculty of Medicine, Universitas Indonesia, Jakarta, 10430, Indonesia	Adawiyah, R., Department of Parasitology, Faculty of Medicine, Universitas Indonesia, Jakarta, 10430, Indonesia, Study Program of Clinical Parasitology, Faculty of Medicine, Universitas Indonesia, Jakarta, 10430, Indonesia, Research Center for Biomedical Engineering, Faculty of Engineering, Universitas Indonesia, Depok, West Java, 16424, Indonesia; Alhaq, A.H., Undergraduate Programm, Faculty of Medicine, Universitas Indonesia, Jakarta, 10430, Indonesia; Mandala, D.K., Department of Chemical Engineering, Faculty of Engineering, Universitas Indonesia, Depok, West Java, 16424, Indonesia; Sahlan, M., Research Center for Biomedical Engineering, Faculty of Engineering, Universitas Indonesia, Depok, West Java, 16424, Indonesia, Department of Chemical Engineering, Faculty of Engineering, Universitas Indonesia, Depok, West Java, 16424, Indonesia; Pratami, D.K., Research Center for Biomedical Engineering, Faculty of Engineering, Universitas Indonesia, Depok, West Java, 16424, Indonesia, Lab of Pharmacognosy and Phytochemistry, Faculty of Pharmacy, Pancasila University, Jakarta, 12640, Indonesia; Farida, S., Research Center for Biomedical Engineering, Faculty of Engineering, Universitas Indonesia, Depok, West Java, 16424, Indonesia, Department of Pharmacy, Faculty of Medicine, Universitas Indonesia, Jakarta, 10430, Indonesia	In recent years, there has been an increase in the incidence of fungal infections accompanied by a decrease in susceptibility to fluconazole as one of the drug choices for fungal infections. So that it needs to be considered the existence of an alternative drug that is effective and also expected to have a minimal side effect, one of which is Propolis. This research was done to determine the effectivity of Indonesian Propolis from Tetragonula biroi bee on the growth of Candida sp. and Cryptococcus neoformans. An experimental study to test the susceptibility of Propolis using disc diffusion technique performed on six types of fungi, e.g. Candida albicans, Candida glabrata, Candida parapsilosis, Candida krusei, Candida tropicalis, dan Cryptococcus neoformans. The samples tested were Indonesian propolis emulsion from Tetragonula biroi bee with a concentration of 10 mg/ml, 50 mg/ml, and 70 mg/ml. The sample selection based on the result of "Exploration of Antifungal Potential of Indonesian Propolis from Tetragonula biroi Bee"from the Faculty of Engineering, University of Indonesia. Indonesian Propolis emulsion from Tetragonula biroi bee can inhibit the growth of Candida sp., especially Candida glabrata and Candida krusei, and also Cryptococcus neoformans with an optimum concentration of 10 mg/ml. The lower concentration than 10 mg/ml of Indonesian Propolis emulsion from Tetragonula biroi bee could be considered to provide more optimal results. © 2021 Author(s).	fungal infection; Indonesian; Propolis; susceptibility test	American Institute of Physics Inc.	0094243X	9780735440869	Conference Paper	-	177	20880	View
505	Hasan A.A.A.F., Supriadi S., Kreshanti P., Umas R.A., Whulanza Y.	57222257599;16040272500;36192866200;57222252781;36807053500;	Concept design and stress evaluation on modular mini plate for complex fracture maxillofacial trauma	2021	AIP Conference Proceedings	2344	050016		https://www.scopus.com/inward/record.uri?eid=2-s2.0-85103490764&doi=10.1063%2f5.0047179&partnerID=40&md5=dc080d2db923ed2607a759c04729c8ef	Department of Mechanical Engineering, Faculty of Engineering, Universitas Indonesia, Kampus UI Depok, West Java, 16424, Indonesia; Research Center for Biomedical Engineering, Faculty of Engineering, Universitas Indonesia, Kampus UI Depok, West Java, 16424, Indonesia; Cleft and Craniofacial Center Cipto Mangunkusumo Hospital, Plastic and Reconstructive Surgery Division, Department of Surgery, Faculty of Medicine, Universitas Indonesia, Jalan Salemba Raya No 6, Jakarta, 10430, Indonesia	Hasan, A.A.A.F., Department of Mechanical Engineering, Faculty of Engineering, Universitas Indonesia, Kampus UI Depok, West Java, 16424, Indonesia; Supriadi, S., Department of Mechanical Engineering, Faculty of Engineering, Universitas Indonesia, Kampus UI Depok, West Java, 16424, Indonesia, Research Center for Biomedical Engineering, Faculty of Engineering, Universitas Indonesia, Kampus UI Depok, West Java, 16424, Indonesia; Kreshanti, P., Cleft and Craniofacial Center Cipto Mangunkusumo Hospital, Plastic and Reconstructive Surgery Division, Department of Surgery, Faculty of Medicine, Universitas Indonesia, Jalan Salemba Raya No 6, Jakarta, 10430, Indonesia; Umas, R.A., Department of Mechanical Engineering, Faculty of Engineering, Universitas Indonesia, Kampus UI Depok, West Java, 16424, Indonesia; Whulanza, Y., Department of Mechanical Engineering, Faculty of Engineering, Universitas Indonesia, Kampus UI Depok, West Java, 16424, Indonesia, Research Center for Biomedical Engineering, Faculty of Engineering, Universitas Indonesia, Kampus UI Depok, West Java, 16424, Indonesia	Complex fracture facial trauma is a condition when some part of the skull shattered into multiple pieces. Intricate fractured skull often deforms the suspect's face, which damaging the aesthetic and the functionality of some part of the skull, or even the whole skull. The procedure to fix this condition uses mini plates in large parts of the procedure. Unfortunately, there is some condition when the existing mini plates can not handle the condition due to the fracture position and another obstacle like teeth root. The lack of mini plates that can adapt according to the obstacles makes the fixation is difficult. This study aims to develop modular mini plates that can adapt the fracture lines and the obstacles that exist in the patients. The method of this study is assembling the modular mini plates to determine the possible angle configuration using CAD software and determining the maximum load of each angle configuration using finite element analysis simulation software. The CAD software result concludes that the possible angle configuration using modular mini plates with 18 holes and pins varies from 40° to 320° with 20° interval (15 configurations). 0°, 20°, and 340° deemed not suitable because the model will collide with each other if using the angle as mentioned earlier configuration. The Von- Mises Stress of each configuration varies, with the maximum value is 535,03 MPa in 240° configuration and the minimum value is 461,26 MPa in 320° configuration with 10 N load configuration. This study concludes that the modular concept is applicable in some angle configuration. © 2021 Author(s).	Complex fracture; Facial trauma; Implant; Mini plate; Modular	American Institute of Physics Inc.	0094243X	9780735440869	Conference Paper	-	177	20880	View
506	Guntara A., Rahyussalim A.J.	56369500300;55212166100;	The uses of lower limb exoskeleton, functional electrical stimulation, and future improvements for leg paralysis management - A systematic review	2021	AIP Conference Proceedings	2344	050015		https://www.scopus.com/inward/record.uri?eid=2-s2.0-85103489541&doi=10.1063%2f5.0047952&partnerID=40&md5=69696a97ac769e4c62286b54212c6cf8	Department of Electrical Engineering, Faculty of Engineering, Universitas Indonesia, Kampus UI Depok, West Java, 16424, Indonesia; Department of Orthopaedic and Traumatology, Faculty of Medicine, Universitas Indonesia, Kampus UI Salemba, DKI Jakarta, 10430, Indonesia	Guntara, A., Department of Electrical Engineering, Faculty of Engineering, Universitas Indonesia, Kampus UI Depok, West Java, 16424, Indonesia; Rahyussalim, A.J., Department of Orthopaedic and Traumatology, Faculty of Medicine, Universitas Indonesia, Kampus UI Salemba, DKI Jakarta, 10430, Indonesia	Introduction: Ambulatory disability is one of the causes of depression and decreased quality of life. The common treatments used by patients are wheelchair, walker, forearm crutches, or immobilization in their house. Other orthoses such as knee ankle foot orthosis (KAFO) is very useful in certain conditions. Replacement therapy with a lower limb exoskeleton may increase the quality of life. The current review aims to evaluate the lower limb exoskeleton with or without functional electrical stimulation (FES) in assisting mobility in paraplegic patients. Methods: A search was performed to identify studies that compared lower limb exoskeleton to KAFO or hybrid exoskeleton with FES in paraplegic patients. Three publications were identified, with subjects ranging from 1 to 3 presenting with spinal injuries between T6 to T10. The measured parameters were locomotion ability, exoskeleton motor power, and torque. Results: The single-use of lower limb exoskeleton in paraplegia patients resulted in 15 sec faster (96s) Timed Up Go (TUG) test, 38 seconds faster (58s) 10-meter walked test (10MWT), and a 27 m farther 6-minute walked test (6MWT) compared to KAFO. The combination of exoskeleton with functional electrical stimulation (FES) reduces muscle fatigue and prevents muscle atrophy by providing stimulus to the muscle that imitates physiological stimulation by nerves. Discussion: Exoskeleton may assist disabled individuals in performing daily routine activity by improving gait, lessening exertion, and thus increasing the quality of life. Further improvement to exoskeleton devices includes integration with FES. Exoskeleton fit on the user also needs to be adjusted to user age and leg dimension to optimize movement and quality of life. © 2021 Author(s).	functional electrical stimulus; lower limb exoskeleton; paraplegia; spinal cord injuries	American Institute of Physics Inc.	0094243X	9780735440869	Conference Paper	-	177	20880	View
507	Khaerunnisa S., Pangjaya L.F., Mazfufah N.F., Budiman R.L., Antarianto R.D.	57221948155;57222624829;57215595521;57222627263;57190862806;	Nidogen-1 (NID1) as specific ligand in natural killer (NK) cells stimulated from advanced ovarian cancer: Immunotherapy review	2021	AIP Conference Proceedings	2344	040009		https://www.scopus.com/inward/record.uri?eid=2-s2.0-85103487578&doi=10.1063%2f5.0049157&partnerID=40&md5=c45066e93f8193a8972229dcd9d4bfb0	Biology Undergraduate Program, Faculty of Mathematics and Natural Science, Universitas Indonesia, Kampus UI Depok, West Java, 16424, Indonesia; Stem Cell and Tissue Engineering Research Cluster, Indonesian Medical Education and Research Institute (IMERI), Universitas Indonesia, Salemba Raya, Jakarta, West Java, 10430, Indonesia; Department of Biology, Faculty of Mathematics and Natural Science, Universitas Indonesia, Kampus UI Depok, West Java, 16424, Indonesia; Department of Histology, Faculty of Medicine, Universitas Indonesia, Salemba Raya, Jakarta, West Java, 10430, Indonesia	Khaerunnisa, S., Biology Undergraduate Program, Faculty of Mathematics and Natural Science, Universitas Indonesia, Kampus UI Depok, West Java, 16424, Indonesia, Stem Cell and Tissue Engineering Research Cluster, Indonesian Medical Education and Research Institute (IMERI), Universitas Indonesia, Salemba Raya, Jakarta, West Java, 10430, Indonesia; Pangjaya, L.F., Biology Undergraduate Program, Faculty of Mathematics and Natural Science, Universitas Indonesia, Kampus UI Depok, West Java, 16424, Indonesia, Stem Cell and Tissue Engineering Research Cluster, Indonesian Medical Education and Research Institute (IMERI), Universitas Indonesia, Salemba Raya, Jakarta, West Java, 10430, Indonesia; Mazfufah, N.F., Stem Cell and Tissue Engineering Research Cluster, Indonesian Medical Education and Research Institute (IMERI), Universitas Indonesia, Salemba Raya, Jakarta, West Java, 10430, Indonesia; Budiman, R.L., Department of Biology, Faculty of Mathematics and Natural Science, Universitas Indonesia, Kampus UI Depok, West Java, 16424, Indonesia; Antarianto, R.D., Stem Cell and Tissue Engineering Research Cluster, Indonesian Medical Education and Research Institute (IMERI), Universitas Indonesia, Salemba Raya, Jakarta, West Java, 10430, Indonesia, Department of Histology, Faculty of Medicine, Universitas Indonesia, Salemba Raya, Jakarta, West Java, 10430, Indonesia	The pathway for the introduction of NK cell into abnormal cells is mediated by the receptor-ligand interaction on the cell surface. Among all the activation receptors, NKP44 has become a unique activation receptor because it has an ITIMs signaling pathway and actively plays an important role in several functions of stimulated NK cells. A potential ligand that can specifically regulate the activity of NKP44 receptors is NID1. NID1 is a novel ligand that can initiate two different regulations on NK cells activity. In addition, NID1 also provides predictions that are compatible with the electrophoretic glycoprotein mobility that has been detected by NKp44 through SDS-PAGE and ELISA tests compared to all proteins in the microenvironment of ovarian cancer. Curently, NID1 has been proven to be able to increase the cytotoxic reaction of non-cancerous NK cells. Further research is needed for the development of ovarian cancer immunotherapy based on the receptor-ligand interactions. © 2021 Author(s).	immunotherapy; NID1; NK cell; NKP44; ovary cancer	American Institute of Physics Inc.	0094243X	9780735440869	Conference Paper	-	177	20880	View
508	Nadhif M.H., Utomo M.S., Ferian M.F., Taufikulhakim F.H., Soerojo N.H.P., Nain M.D., Yusuf P.A., Susanto A.P., Prasetyono T.O.H.	57189057498;56180933900;57222626931;57222619312;57222624010;57222621216;57192156597;57221504275;26646993900;	Cost-efficacy of skin grafting techniques using negative pressure wound therapy and tissue-engineered skin for burns	2021	AIP Conference Proceedings	2344	050008		https://www.scopus.com/inward/record.uri?eid=2-s2.0-85103487191&doi=10.1063%2f5.0047187&partnerID=40&md5=166e12d943897b27d5a5f4ebaaf1ddef	Department of Medical Physics, Faculty of Medicine, Universitas Indonesia, Jl. Salemba Raya No. 6, Central Jakarta, DKI Jakarta, 10430, Indonesia; Medical Technology Cluster, Indonesian Medical Education and Research Institute, Universitas Indonesia, Jl. Salemba Raya No. 6, Central Jakarta, DKI Jakarta, 10430, Indonesia; Research Center for Metallurgy and Materials, Indonesian Institute of Sciences, PUSPIPTEK Building 470, South Tangerang, Banten, 15314, Indonesia; Undergraduate Program, Faculty of Medicine, Universitas Indonesia, Jl. Salemba Raya No. 6, Central Jakarta, DKI Jakarta, 10430, Indonesia; Division of Plastic Surgery, Department of Surgery, Cipto Mangunkusumo Central Hospital, Faculty of Medicine, Universitas Indonesia, Jl. Salemba Raya No. 6, Central Jakarta, DKI Jakarta, 10430, Indonesia; Indonesian Clinical Training and Education Centre (ICTEC), Cipto Mangunkusumo Central Hospital, Jl. Pangeran Diponegoro No. 71, Senen, Central Jakarta, DKI Jakarta, 10430, Indonesia	Nadhif, M.H., Department of Medical Physics, Faculty of Medicine, Universitas Indonesia, Jl. Salemba Raya No. 6, Central Jakarta, DKI Jakarta, 10430, Indonesia, Medical Technology Cluster, Indonesian Medical Education and Research Institute, Universitas Indonesia, Jl. Salemba Raya No. 6, Central Jakarta, DKI Jakarta, 10430, Indonesia; Utomo, M.S., Department of Medical Physics, Faculty of Medicine, Universitas Indonesia, Jl. Salemba Raya No. 6, Central Jakarta, DKI Jakarta, 10430, Indonesia, Medical Technology Cluster, Indonesian Medical Education and Research Institute, Universitas Indonesia, Jl. Salemba Raya No. 6, Central Jakarta, DKI Jakarta, 10430, Indonesia, Research Center for Metallurgy and Materials, Indonesian Institute of Sciences, PUSPIPTEK Building 470, South Tangerang, Banten, 15314, Indonesia; Ferian, M.F., Undergraduate Program, Faculty of Medicine, Universitas Indonesia, Jl. Salemba Raya No. 6, Central Jakarta, DKI Jakarta, 10430, Indonesia; Taufikulhakim, F.H., Undergraduate Program, Faculty of Medicine, Universitas Indonesia, Jl. Salemba Raya No. 6, Central Jakarta, DKI Jakarta, 10430, Indonesia; Soerojo, N.H.P., Undergraduate Program, Faculty of Medicine, Universitas Indonesia, Jl. Salemba Raya No. 6, Central Jakarta, DKI Jakarta, 10430, Indonesia; Nain, M.D., Undergraduate Program, Faculty of Medicine, Universitas Indonesia, Jl. Salemba Raya No. 6, Central Jakarta, DKI Jakarta, 10430, Indonesia; Yusuf, P.A., Department of Medical Physics, Faculty of Medicine, Universitas Indonesia, Jl. Salemba Raya No. 6, Central Jakarta, DKI Jakarta, 10430, Indonesia, Medical Technology Cluster, Indonesian Medical Education and Research Institute, Universitas Indonesia, Jl. Salemba Raya No. 6, Central Jakarta, DKI Jakarta, 10430, Indonesia; Susanto, A.P., Department of Medical Physics, Faculty of Medicine, Universitas Indonesia, Jl. Salemba Raya No. 6, Central Jakarta, DKI Jakarta, 10430, Indonesia, Medical Technology Cluster, Indonesian Medical Education and Research Institute, Universitas Indonesia, Jl. Salemba Raya No. 6, Central Jakarta, DKI Jakarta, 10430, Indonesia; Prasetyono, T.O.H., Medical Technology Cluster, Indonesian Medical Education and Research Institute, Universitas Indonesia, Jl. Salemba Raya No. 6, Central Jakarta, DKI Jakarta, 10430, Indonesia, Division of Plastic Surgery, Department of Surgery, Cipto Mangunkusumo Central Hospital, Faculty of Medicine, Universitas Indonesia, Jl. Salemba Raya No. 6, Central Jakarta, DKI Jakarta, 10430, Indonesia, Indonesian Clinical Training and Education Centre (ICTEC), Cipto Mangunkusumo Central Hospital, Jl. Pangeran Diponegoro No. 71, Senen, Central Jakarta, DKI Jakarta, 10430, Indonesia	Burns, which generate hypertrophic scar formation, may decrease functional and aesthetical aspects of patients' quality of life. To date, grafting treatments were not only proceeded solitarily. The technological development of burn treatments emerged with approaches, such as negative pressure wound therapy (NPWT) and tissue-engineered skin (TES). By incorporating negative pressure on the wound bed, NPWT was able to remove debris, remove exudates, maintain humidity, and improve epithelization. A latter development of wound management, TES, also showed prominent results of wound healing. Benefitting from tissue engineering approaches, TES provided the wound bed with extracellular matrix (ECM) and 3D structure to support wound healing. In some reports, NPWT was combined with TES to promote better efficacy. Unfortunately, the efficacies of NPWT, TES, or NPWT-TES hybrid as assisting approaches for skin drafting techniques are not reviewed yet, as well as the cost comparison of the three treatments. In this report, the comparison of skin grafting techniques assisted with the three treatments (NPWT, TES, or NPWT-TES hybrid) was investigated in terms of efficacy and cost. The review starts with brief technical aspects of the three treatments. Subsequently, the efficacy and cost analyses were discussed. © 2021 Author(s).	cost; efficacy; grafting; NPWT; TES	American Institute of Physics Inc.	0094243X	9780735440869	Conference Paper	-	177	20880	View
509	Yusuf P.A., Susanto A.P., Amelia A.Z., Supandi D.P., Septhendy, Nadhif M.H., Utomo M.S., Hamid A.R.A.H.	57192156597;57221504275;57222626360;57222624055;57222622640;57189057498;56180933900;57202054669;	Recent updates in artificial kidney technology: Potential parsing for universal coverage burden of chronic kidney disease in Indonesia	2021	AIP Conference Proceedings	2344	050020		https://www.scopus.com/inward/record.uri?eid=2-s2.0-85103484551&doi=10.1063%2f5.0047542&partnerID=40&md5=4e38248c7fa9c1f7c684e7eff9de9e5a	Department of Medical Physics, Faculty of Medicine, Universitas Indonesia, Jl. Salemba Raya No. 6, Jakarta, 10340, Indonesia; Medical Technology Cluster, Indonesian Medical Education and Research Institute (IMERI), Faculty of Medicine, Universitas Indonesia, Jl. Salemba Raya No. 6, Jakarta, 10340, Indonesia; Undergraduate Program, Faculty of Medicine, Universitas Indonesia, Jl. Salemba Raya No. 6, Jakarta, 10340, Indonesia; Research Center for Metallurgy and Material, Indonesia Institute of Science (LIPI), Banten, 15310, Indonesia; Department of Urology, Cipto Mangunkusumo Hospital, Faculty of Medicine, Universitas Indonesia, Jl. Salemba Raya No. 6, Jakarta, 10340, Indonesia	Yusuf, P.A., Department of Medical Physics, Faculty of Medicine, Universitas Indonesia, Jl. Salemba Raya No. 6, Jakarta, 10340, Indonesia, Medical Technology Cluster, Indonesian Medical Education and Research Institute (IMERI), Faculty of Medicine, Universitas Indonesia, Jl. Salemba Raya No. 6, Jakarta, 10340, Indonesia; Susanto, A.P., Department of Medical Physics, Faculty of Medicine, Universitas Indonesia, Jl. Salemba Raya No. 6, Jakarta, 10340, Indonesia, Medical Technology Cluster, Indonesian Medical Education and Research Institute (IMERI), Faculty of Medicine, Universitas Indonesia, Jl. Salemba Raya No. 6, Jakarta, 10340, Indonesia; Amelia, A.Z., Undergraduate Program, Faculty of Medicine, Universitas Indonesia, Jl. Salemba Raya No. 6, Jakarta, 10340, Indonesia; Supandi, D.P., Undergraduate Program, Faculty of Medicine, Universitas Indonesia, Jl. Salemba Raya No. 6, Jakarta, 10340, Indonesia; Septhendy, Undergraduate Program, Faculty of Medicine, Universitas Indonesia, Jl. Salemba Raya No. 6, Jakarta, 10340, Indonesia; Nadhif, M.H., Department of Medical Physics, Faculty of Medicine, Universitas Indonesia, Jl. Salemba Raya No. 6, Jakarta, 10340, Indonesia, Medical Technology Cluster, Indonesian Medical Education and Research Institute (IMERI), Faculty of Medicine, Universitas Indonesia, Jl. Salemba Raya No. 6, Jakarta, 10340, Indonesia; Utomo, M.S., Department of Medical Physics, Faculty of Medicine, Universitas Indonesia, Jl. Salemba Raya No. 6, Jakarta, 10340, Indonesia, Medical Technology Cluster, Indonesian Medical Education and Research Institute (IMERI), Faculty of Medicine, Universitas Indonesia, Jl. Salemba Raya No. 6, Jakarta, 10340, Indonesia, Research Center for Metallurgy and Material, Indonesia Institute of Science (LIPI), Banten, 15310, Indonesia; Hamid, A.R.A.H., Department of Urology, Cipto Mangunkusumo Hospital, Faculty of Medicine, Universitas Indonesia, Jl. Salemba Raya No. 6, Jakarta, 10340, Indonesia	Chronic Kidney Disease has high mortality and financial burden. It was the third most catastrophic and expensive disease protected by universal coverage. The growth of medical technology gives hope to solve this hardship potentially. This paper aims to review current and future developments of artificial kidney technologies from different aspects. The scoops are popularity, cost-effectiveness, liters of dialysate needed, portability, safety issues, adverse effect reports, quality of life, the availability, and the number of professional medical workers needed to operate the device. The currently available treatments such as hemodialysis, peritoneal dialysis, and kidney transplantation have its benefits and challenges. Peritoneal dialysis gives a better quality of life and more cost-effective, however, it has the highest dropout ratio. The future artificial kidneys, such as the wearable artificial kidney, automated wearable artificial kidney, and implantable artificial kidney, offer solutions to overcome the existing challenges. Although the new technologies have not yet reached the Indonesian market, the potential benefits are high in helping chronic kidney disease patients - by offering simplicity, accessibility, reachability, and affordability of the treatment. © 2021 Author(s).	Artificial kidney; Chronic kidney disease; Medical technology	American Institute of Physics Inc.	0094243X	9780735440869	Conference Paper	-	177	20880	View
510	Rahyussalim A.J., Marsetio A.F., Kurniawati T.	55212166100;57192180884;55213290600;	Rod and screw corrective manipulation technique, an alternative technique for rigid and severe scoliosis correction management	2021	AIP Conference Proceedings	2344	050022		https://www.scopus.com/inward/record.uri?eid=2-s2.0-85103484021&doi=10.1063%2f5.0047983&partnerID=40&md5=a08a9b1f3ede725651914e30e3021176	Department of Orthopaedics and Traumatology, Faculty of Medicine, Universitas Indonesia, Cipto Mangunkusumo Hospital, Jakarta, 10320, Indonesia; Stem Cell Medical Technology Integrated Service Unit, Cipto Mangunkusumo Hospital, Faculty of Medicine, Universitas Indonesia, Jakarta, 10320, Indonesia; Stem Cell and Tissue Engineering Research Center, Indonesia Medical Education and Research Institute (IMERI), Faculty of Medicine, Universitas Indonesia, Jakarta, 10320, Indonesia	Rahyussalim, A.J., Department of Orthopaedics and Traumatology, Faculty of Medicine, Universitas Indonesia, Cipto Mangunkusumo Hospital, Jakarta, 10320, Indonesia, Stem Cell Medical Technology Integrated Service Unit, Cipto Mangunkusumo Hospital, Faculty of Medicine, Universitas Indonesia, Jakarta, 10320, Indonesia, Stem Cell and Tissue Engineering Research Center, Indonesia Medical Education and Research Institute (IMERI), Faculty of Medicine, Universitas Indonesia, Jakarta, 10320, Indonesia; Marsetio, A.F., Department of Orthopaedics and Traumatology, Faculty of Medicine, Universitas Indonesia, Cipto Mangunkusumo Hospital, Jakarta, 10320, Indonesia; Kurniawati, T., Stem Cell Medical Technology Integrated Service Unit, Cipto Mangunkusumo Hospital, Faculty of Medicine, Universitas Indonesia, Jakarta, 10320, Indonesia, Stem Cell and Tissue Engineering Research Center, Indonesia Medical Education and Research Institute (IMERI), Faculty of Medicine, Universitas Indonesia, Jakarta, 10320, Indonesia	The terms correction and manipulation in the surgical management of scoliosis define a harmonization of several measures performed individually or simultaneously to realign a deformed spine into its normal state on sagittal or coronal views. Scoliosis surgical procedures are modified due to the fact that they are complex procedures with frequent complications and unsatisfactory surgical outcomes. This technique combines rod and screws corrective manipulations applied to each vertebral segment according to the pathobiomechanic state of the deformity to simplify the manipulation process and achieve a good surgical outcome. A preliminary experimental study was done on modifications to the screw application technique, rod application for vertebral segment maneuver techniques during manipulation, and connecting rod use. Surgical outcomes were compared between the rod and screw corrective manipulation (RSCM) and conventional techniques in patients who underwent corrective surgery for scoliosis. Twelve scoliosis patients who underwent the RSCM technique had better complication rates, operative time, estimated blood loss, length of hospital stay, and sagittal alignment correction outcome compared with the 15 scoliosis patients who underwent surgery via the conventional technique. The RSCM technique was not complex, and it was easy to apply and provided better corrective outcomes. Hence, this is a promising treatment of choice for the surgical management of scoliosis patients. © 2021 Author(s).	connecting rod; corrective manipulation; extreme scoliosis; scoliosis correction	American Institute of Physics Inc.	0094243X	9780735440869	Conference Paper	-	177	20880	View

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