855 |
Syahrul S., Maliga H.A., Ilmawan M., Fahriani M., Mamada S.S., Fajar J.K., Frediansyah A., Syahrul F.N., Imran I., Haris S., Rambe A.S., Emran T.B., Rabaan A.A., Tiwari R., Dhama K., Nainu F., Mutiawati E., Harapan H. |
57216064819;57222334227;57217182580;57219947648;57211891425;56156139600;56897210000;57222337525;56589826700;57222343545;57193757980;55325267100;56049830800;55314856100;6507396956;57120069200;56652288600;55844857500; |
Hemorrhagic and ischemic stroke in patients with coronavirus disease 2019: Incidence, risk factors, and pathogenesis - a systematic review and meta-analysis |
2021 |
F1000Research |
10 |
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34 |
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12 |
https://www.scopus.com/inward/record.uri?eid=2-s2.0-85102340647&doi=10.12688%2ff1000research.42308.1&partnerID=40&md5=8cfb8151ce9b8e51bb3ec5847e7a2ca5 |
Department of Neurology, School of Medicine, Universitas Syiah Kuala, Banda Aceh, Aceh, 23111, Indonesia; Department of Neurology, Dr. Zainoel Abidin Hospital, Banda Aceh, Aceh, 23111, Indonesia; Faculty of Medicine, Universitas Brawijaya, Malang, East Java, 65117, Indonesia; Medical Research Unit, School of Medicine, Universitas Syiah Kuala, Banda Aceh, Aceh, 23111, Indonesia; Faculty of Pharmacy, Hasanuddin University, Makassar, South Sulawesi, 90245, Indonesia; Brawijaya Internal Medicine Research Center, Department of Internal Medicine, Faculty of Medicine, Universitas Brawijaya, Malang, East Java, 65145, Indonesia; Research Division for Natural Product Technology (BPTBA), Indonesian Institute of Sciences (LIPI), Wonosari, 55861, Indonesia; Department of Neurology, Faculty of Medicine, Universitas Indonesia, Jakarta, 10430, Indonesia; Department of Neurology, Faculty of Medicine, Universitas Sumatera Utara, Medan, North Sumatra, 20155, Indonesia; Department of Pharmacy, BGC Trust University Bangladesh, Chittagong, 4381, Bangladesh; Molecular Diagnostic Laboratory, Johns Hopkins Aramco Healthcare, Dhahran, 31311, Saudi Arabia; Department of Veterinary Microbiology and Immunology, College of Veterinary Sciences, UP Pandit Deen Upadhayay Pashu Chikitsa Vigyan Vishwavidyalay Evum Go-Anusandhan Sansthan (DUVASU), Mathura, Uttar Pradesh, 281 001, India; Division of Pathology, ICAR-Indian Veterinary Research Institute, Izatnagar, Uttar Pradesh, 243122, India; Department of Microbiology, School of Medicine, Universitas Syiah Kuala, Banda Aceh, Aceh, 23111, Indonesia; Tropical Disease Centre, School of Medicine, Universitas Syiah Kuala, Banda Aceh, Aceh, 23111, Indonesia |
Syahrul, S., Department of Neurology, School of Medicine, Universitas Syiah Kuala, Banda Aceh, Aceh, 23111, Indonesia, Department of Neurology, Dr. Zainoel Abidin Hospital, Banda Aceh, Aceh, 23111, Indonesia; Maliga, H.A., Faculty of Medicine, Universitas Brawijaya, Malang, East Java, 65117, Indonesia; Ilmawan, M., Faculty of Medicine, Universitas Brawijaya, Malang, East Java, 65117, Indonesia; Fahriani, M., Medical Research Unit, School of Medicine, Universitas Syiah Kuala, Banda Aceh, Aceh, 23111, Indonesia; Mamada, S.S., Faculty of Pharmacy, Hasanuddin University, Makassar, South Sulawesi, 90245, Indonesia; Fajar, J.K., Faculty of Medicine, Universitas Brawijaya, Malang, East Java, 65117, Indonesia, Brawijaya Internal Medicine Research Center, Department of Internal Medicine, Faculty of Medicine, Universitas Brawijaya, Malang, East Java, 65145, Indonesia; Frediansyah, A., Research Division for Natural Product Technology (BPTBA), Indonesian Institute of Sciences (LIPI), Wonosari, 55861, Indonesia; Syahrul, F.N., Department of Neurology, School of Medicine, Universitas Syiah Kuala, Banda Aceh, Aceh, 23111, Indonesia; Imran, I., Department of Neurology, School of Medicine, Universitas Syiah Kuala, Banda Aceh, Aceh, 23111, Indonesia, Department of Neurology, Dr. Zainoel Abidin Hospital, Banda Aceh, Aceh, 23111, Indonesia; Haris, S., Department of Neurology, Faculty of Medicine, Universitas Indonesia, Jakarta, 10430, Indonesia; Rambe, A.S., Department of Neurology, Faculty of Medicine, Universitas Sumatera Utara, Medan, North Sumatra, 20155, Indonesia; Emran, T.B., Department of Pharmacy, BGC Trust University Bangladesh, Chittagong, 4381, Bangladesh; Rabaan, A.A., Molecular Diagnostic Laboratory, Johns Hopkins Aramco Healthcare, Dhahran, 31311, Saudi Arabia; Tiwari, R., Department of Veterinary Microbiology and Immunology, College of Veterinary Sciences, UP Pandit Deen Upadhayay Pashu Chikitsa Vigyan Vishwavidyalay Evum Go-Anusandhan Sansthan (DUVASU), Mathura, Uttar Pradesh, 281 001, India; Dhama, K., Division of Pathology, ICAR-Indian Veterinary Research Institute, Izatnagar, Uttar Pradesh, 243122, India; Nainu, F., Faculty of Pharmacy, Hasanuddin University, Makassar, South Sulawesi, 90245, Indonesia; Mutiawati, E., Department of Neurology, School of Medicine, Universitas Syiah Kuala, Banda Aceh, Aceh, 23111, Indonesia, Department of Neurology, Dr. Zainoel Abidin Hospital, Banda Aceh, Aceh, 23111, Indonesia; Harapan, H., Medical Research Unit, School of Medicine, Universitas Syiah Kuala, Banda Aceh, Aceh, 23111, Indonesia, Department of Microbiology, School of Medicine, Universitas Syiah Kuala, Banda Aceh, Aceh, 23111, Indonesia, Tropical Disease Centre, School of Medicine, Universitas Syiah Kuala, Banda Aceh, Aceh, 23111, Indonesia |
Background: In this study, we aimed to determine the global prevalence, chronological order of symptom appearance, and mortality rates with regard to hemorrhagic and ischemic stroke in patients with coronavirus disease 2019 (COVID-19) and to discuss possible pathogeneses of hemorrhagic and ischemic stroke in individuals with the disease. Methods: We searched the PubMed, Scopus, and Web of Science databases for relevant articles published up to November 8, 2020. Data regarding study characteristics, hemorrhagic stroke, ischemic stroke, and COVID-19 were retrieved in accordance with the PRISMA guidelines. The Newcastle-Ottawa scale was used to assess the quality of the eligible studies. The pooled prevalence and mortality rate of hemorrhagic and ischemic stroke were calculated. Results: The pooled estimate of prevalence of hemorrhagic stroke was 0.46% (95% CI 0.40%-0.53%; I 2 =89.81%) among 67,155 COVID-19 patients and that of ischemic stroke was 1.11% (95% CI 1.03%-1.22%; I 2 =94.07%) among 58,104 COVID-19 patients. Ischemic stroke was more predominant (incidence: 71.58%) than hemorrhagic stroke (incidence: 28.42%) in COVID-19 patients who experienced a stroke. In COVID-19 patients who experienced a stroke, hospital admission with respiratory symptoms was more commonly reported than that with neurological symptoms (20.83% for hemorrhagic stroke and 5.51% for ischemic stroke versus 6.94% for hemorrhagic stroke and 5.33% for ischemic stroke, respectively). The pooled mortality rate of COVID-19 patients who experienced a hemorrhagic and ischemic stroke was 44.72% (95% CI 36.73%-52.98%) and 36.23% (95% CI 30.63%-42.24%), respectively. Conclusions: Although the occurrence of hemorrhagic and ischemic stroke is low, the mortality rates of both stroke types in patients with COVID-19 are concerning, and therefore, despite several potential pathogeneses that have been proposed, studies aimed at definitively elucidating the mechanisms of hemorrhagic and ischemic stroke in individuals with COVID-19 are warranted. PROSPERO registration: CRD42020224470 (04/12/20) © 2021 Syahrul S et al. |
COVID-19; Haemorrhagic stroke; Ischemic stroke; Meta-analysis; Pathogenesis; SARS-CoV-2; Systematic review |
Article; brain hemorrhage; clinical feature; clinical outcome; coronavirus disease 2019; hospital admission; human; incidence; ischemic stroke; meta analysis (topic); mortality rate; neurologic disease; Newcastle-Ottawa scale; pathogenesis; pooled analysis; Preferred Reporting Items for Systematic Reviews and Meta-Analyses; publication bias; respiratory tract disease; risk factor; statistical analysis; symptom; systematic review; brain ischemia; complication; incidence; meta analysis; prospective study; retrospective study; risk factor; Brain Ischemia; COVID-19; Humans; Incidence; Ischemic Stroke; Prospective Studies; Retrospective Studies; Risk Factors |
F1000 Research Ltd |
20461402 |
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33708378 |
Article |
Q1 |
1099 |
3793 |
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881 |
Harzif A., Hyaswicaksono P., Kurniawan R., Wiweko B. |
57191493435;57221907604;57196055951;43061741400; |
Heterotopic pregnancy: Diagnosis and pitfall in ultrasonography |
2021 |
Gynecology and Minimally Invasive Therapy |
10 |
1 |
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53 |
56 |
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1 |
https://www.scopus.com/inward/record.uri?eid=2-s2.0-85100537776&doi=10.4103%2fGMIT.GMIT_92_19&partnerID=40&md5=ba933e51def94298b03a38705981ed87 |
Department of Obstetrics and Gynecology, Reproductive Immunology and Endocrinology Division, Faculty of Medicine, Dr. Cipto Mangunkusumo General Hospital, Universitas Indonesia, Jakarta, Indonesia; Department of Obstetrics and Gynecology, Faculty of Medicine, Dr. Cipto Mangunkusumo General Hospital, Universitas Indonesia, Jl. Diponegoro No. 71, Jakarta Pusat, 10340, Indonesia |
Harzif, A., Department of Obstetrics and Gynecology, Reproductive Immunology and Endocrinology Division, Faculty of Medicine, Dr. Cipto Mangunkusumo General Hospital, Universitas Indonesia, Jakarta, Indonesia; Hyaswicaksono, P., Department of Obstetrics and Gynecology, Faculty of Medicine, Dr. Cipto Mangunkusumo General Hospital, Universitas Indonesia, Jl. Diponegoro No. 71, Jakarta Pusat, 10340, Indonesia; Kurniawan, R., Department of Obstetrics and Gynecology, Faculty of Medicine, Dr. Cipto Mangunkusumo General Hospital, Universitas Indonesia, Jl. Diponegoro No. 71, Jakarta Pusat, 10340, Indonesia; Wiweko, B., Department of Obstetrics and Gynecology, Reproductive Immunology and Endocrinology Division, Faculty of Medicine, Dr. Cipto Mangunkusumo General Hospital, Universitas Indonesia, Jakarta, Indonesia |
Heterotopic pregnancy (HP) is the coexistence of extrauterine and intrauterine pregnancies. This case is rare, difficult to diagnose, and threatening if left untreated. Incidental rate is estimated 1 in 30,000 spontaneous pregnancies and higher in assisted reproductive techniques. HP is often missed because of the detection of intrauterine sacs; therefore, comprehensive and systematic ultrasonography (USG) is needed, especially when there is ectopic pregnancy suspicion or when there is free fluid in the pelvis. A 46-year nulligravida with 13-year primary infertility history underwent frozen embryo transfer process with positive beta-human chorionic gonadotropin 2 weeks after the procedure. Clinical pregnancy is expressed by gestational sac findings at 6-week gestation. Two weeks later, she complained of lower right abdominal pain accompanied by spots from the birth canal. USG showed intrauterine pregnancy and sac appropriate to 8-week gestation and adnexal mass accompanied by a ring of fire image. The patient underwent right salpingectomy, recovered well, and continued her pregnancy. In vitro fertilization is the main risk factor for multiple and ectopic pregnancies. Clinical manifestations are similar to pregnancy loss or ectopic pregnancy. Specific risk factor must be acknowledged by the physician prior initial examination to rule out HP. Transvaginal ultrasound is useful in making the diagnosis of HP, especially in early pregnancy. © 2021 Wolters Kluwer Medknow Publications. All rights reserved. |
Heterotopic; laparoscopy; ultrasound |
chorionic gonadotropin beta subunit; progesterone; abdominal pain; adnexa disease; adult; Article; case report; clinical article; ectopic pregnancy; embryo transfer; female; female infertility; first trimester pregnancy; gestational sac; human; in vitro fertilization; middle aged; priority journal; risk factor; salpingectomy; transvaginal echography; uterine adnexa |
Wolters Kluwer Medknow Publications |
22133070 |
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Article |
Q3 |
441 |
11202 |
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