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462 |
Siste K., Hanafi E., Sen L.T., Wahjoepramono P.O.P., Kurniawan A., Yudistiro R. |
55644113100;56737010600;57219034101;57216247534;56521213900;57041205200; |
Potential correlates of internet gaming disorder among Indonesian medical students: Cross-sectional study |
2021 |
Journal of Medical Internet Research |
23 |
4 |
e25468 |
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2 |
https://www.scopus.com/inward/record.uri?eid=2-s2.0-85104418234&doi=10.2196%2f25468&partnerID=40&md5=9877dd97d733cb4ea58465ec70c69a79 |
Department of Psychiatry, Faculty of Medicine, Universitas Indonesia, Dr Cipto Mangunkusumo General Hospital, Jakarta, Indonesia; Faculty of Medicine, Universitas Pelita Harapan, Siloam Hospitals, Tangerang, Indonesia; Department of Internal Medicine, Faculty of Medicine, Universitas Pelita, Harapan Siloam Hospital, Tangerang, Indonesia |
Siste, K., Department of Psychiatry, Faculty of Medicine, Universitas Indonesia, Dr Cipto Mangunkusumo General Hospital, Jakarta, Indonesia; Hanafi, E., Department of Psychiatry, Faculty of Medicine, Universitas Indonesia, Dr Cipto Mangunkusumo General Hospital, Jakarta, Indonesia; Sen, L.T., Department of Psychiatry, Faculty of Medicine, Universitas Indonesia, Dr Cipto Mangunkusumo General Hospital, Jakarta, Indonesia; Wahjoepramono, P.O.P., Faculty of Medicine, Universitas Pelita Harapan, Siloam Hospitals, Tangerang, Indonesia; Kurniawan, A., Department of Internal Medicine, Faculty of Medicine, Universitas Pelita, Harapan Siloam Hospital, Tangerang, Indonesia; Yudistiro, R., Faculty of Medicine, Universitas Pelita Harapan, Siloam Hospitals, Tangerang, Indonesia |
Background: Internet gaming disorder has been a controversial topic for nearly a decade. Although internet addiction has been studied in medical students, there is a paucity of evidence regarding internet gaming disorder. Previous studies in Indonesia explored only the prevalence rate and characteristics. Objective: This study aimed to determine the prevalence rate of internet gaming disorder and correlations between internet gaming disorder, temperament, and psychopathology among Indonesian medical students. Methods: A cross-sectional study was performed from August 2019 to September 2019 using total and convenience sampling at a private university and a public university, respectively. The study variables were measured using the Indonesian version of the 10-item Internet Gaming Disorder Test, the Temperament and Character Inventory, and the Symptoms Checklist 90. Chi-square and logistic regression analyses were conducted to examine the relationships between demographic factors, temperament, psychopathology, and the presence of internet gaming disorder. Results: Among the 639 respondents, the prevalence rate of internet gaming disorder was 2.03% (n=13), with a mean age of 20.23 (SD 0.13) years and an average gaming duration of 19.0 (SD 0.96) hours/week. Up to 71.2% respondents played using their mobile phones, and respondents with internet gaming disorder reported experiencing all psychopathologies assessed, except phobic anxiety. Bivariate analysis demonstrated that internet gaming disorder was associated with gender, gaming duration, gaming community affiliation, and 9 out of 10 domains of psychopathology. In a logistic regression model, internet gaming disorder was correlated with weekly gaming hours ≥20 hours (odds ratio [OR] 4.21, 95% CI 1.08-16.38, P=.04). Conclusions: These findings suggest that the prevalence of internet gaming disorder among medical students in Jakarta, Indonesia is similar to that in other populations of Asian countries. The predisposing factor for internet gaming disorder was weekly gaming duration, while other demographic, temperament, and psychopathology variables acted as probable moderators. Strategies should, therefore, be developed and integrated into medical curriculum to screen and aid individuals with these predisposing factors. © Kristiana Siste, Enjeline Hanafi, Lee Thung Sen, Petra Octavian Perdana Wahjoepramono, Ryan Yudistiro, Ryan Yudistiro. Originally published in the Journal of Medical Internet Research (https://www.jmir.org), 19.04.2021. This is an open-access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work, first published in the Journal of Medical Internet Research, is properly cited. The complete bibliographic information, a link to the original publication on http://www.jmir.org/, as well as this copyright and license information must be included. |
Internet gaming disorder; Medical students; Psychopathology; Risk factors; Temperament |
adult; anxiety disorder; Article; comparative study; correlational study; cross-sectional study; demography; depression; disease association; female; game addiction; hostility; human; Indonesia; internet gaming disorder test; major clinical study; male; medical student; mental disease assessment; neuropathology; obsessive compulsive disorder; online game; paranoia; prevalence; questionnaire; sex difference; somatization; Symptom Checklist 90; temperament; temperament and character inventory; young adult; addiction; Internet; internet addiction; video game; Adult; Behavior, Addictive; Cross-Sectional Studies; Humans; Indonesia; Internet; Internet Addiction Disorder; Students, Medical; Video Games; Young Adult |
JMIR Publications Inc. |
14388871 |
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33871379 |
Article |
Q1 |
1446 |
2408 |
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468 |
Prasetyo M., Moniqa R., Tulaar A., Prihartono J., Setiawan S.I. |
57192905252;57221866634;24330360800;6602605635;57195939543; |
Correlation between Hemophilia Early Arthropathy Detection with Ultrasound (HEAD-US) score and Hemophilia Joint Health Score (HJHS) in patients with hemophilic arthropathy |
2021 |
PLoS ONE |
16 |
4 April |
e0248952 |
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2 |
https://www.scopus.com/inward/record.uri?eid=2-s2.0-85103995985&doi=10.1371%2fjournal.pone.0248952&partnerID=40&md5=33018f7adcb5c975c29264deba385db3 |
Department of Radiology, Faculty of Medicine Universitas Indonesia-Dr. Cipto Mangunkusumo National Central General Hospital, Jakarta, Indonesia; Department of Medical Rehabilitation, Faculty of Medicine Universitas Indonesia-Dr. Cipto Mangunkusumo National Central General Hospital, Jakarta, Indonesia; Department of Community Medicine, Faculty of Medicine Universitas Indonesia, Jakarta, Indonesia |
Prasetyo, M., Department of Radiology, Faculty of Medicine Universitas Indonesia-Dr. Cipto Mangunkusumo National Central General Hospital, Jakarta, Indonesia; Moniqa, R., Department of Radiology, Faculty of Medicine Universitas Indonesia-Dr. Cipto Mangunkusumo National Central General Hospital, Jakarta, Indonesia; Tulaar, A., Department of Medical Rehabilitation, Faculty of Medicine Universitas Indonesia-Dr. Cipto Mangunkusumo National Central General Hospital, Jakarta, Indonesia; Prihartono, J., Department of Community Medicine, Faculty of Medicine Universitas Indonesia, Jakarta, Indonesia; Setiawan, S.I., Department of Radiology, Faculty of Medicine Universitas Indonesia-Dr. Cipto Mangunkusumo National Central General Hospital, Jakarta, Indonesia |
Background Hemophilic arthropathy, a condition manifested as joint destruction due to spontaneous joint bleeding, is one complication of hemophiliac patients. Early detection and intervention may improve the outcome, in which ultrasonography can be an ideal modality with the introduction of HEAD-US (Hemophilia Early Arthropathy Detection with Ultrasound) protocol. Studies have shown US benefit in hemophiliac patients, including its potential as an alternative for the Hemophiliac Joint Health Score (HJHS) system. However, many of the studies were conducted in countries with better management of hemophilia using prophylaxis treatment. It is unclear whether HEAD-US has a correlation with HJHS in countries using episodic treatment only, like in Indonesia. Purpose This study aimed to explore the correlation between HEAD-US and HJHS in hemophiliac patients with joint problems in Indonesia. Materials and methods A cross-sectional correlation study between HEAD-US and HJHS was performed with primary data collected from 120 hemophilic patients. US examination was performed on elbow, knee and ankle joints using the HEAD-US scoring method by a musculoskeletal radiologist. HJHS examination was conducted by a trained physiotherapist and a medical rehabilitation specialist. All examiner is member of multidisciplinary Hemophiliac Management Team in Cipto Mangunkusumo General Hospital in Jakarta, Indonesia. Results The mean age of the participant was 9.3 (5-14) years old. The median score of HEAD-US was 8 (1-28) with most of the joint abnormalities found on the ankles. The median score of HJHS was 3 (0-35), with most joint abnormalities found on the knees. There was a moderate correlation between HEAD-US and HJHS score (p < 0.05, r = 0.65). Conclusion HEAD-US shows a moderate correlation to HJHS in hemophiliac patients who received episodic treatment. HEAD-US can provide additional value in the anatomical evaluation of the joint and could be complementary to HJHS in assessing the joint status in hemophilic patient. © 2021 Prasetyo et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. |
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adolescent; ankle; Article; child; controlled study; correlational study; cross-sectional study; disease assessment; echography; elbow; Hemophilia Early Arthropathy Detection with Ultrasound score; Hemophilia Joint Health Score; hemophilic arthropathy; human; Indonesia; information processing; knee; major clinical study; medical specialist; musculoskeletal radiologist; physiotherapist; scoring system; arthropathy; diagnostic imaging; early diagnosis; echography; hemophilia A; joint; pathology; preschool child; procedures; Adolescent; Child; Child, Preschool; Cross-Sectional Studies; Early Diagnosis; Hemophilia A; Humans; Indonesia; Joint Diseases; Joints; Ultrasonography |
Public Library of Science |
19326203 |
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33826621 |
Article |
Q1 |
990 |
4434 |
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480 |
Sukmawan R., Hoetama E., Suridanda Danny S., Giantini A., Listiyaningsih E., Gilang Rejeki V., Aziz Alkatiri A., Firdaus I. |
8651025300;57214138849;57222312102;12776781400;57224237184;57222313503;57222311692;55796864700; |
Increase in the risk of clopidogrel resistance and consequent TIMI flow impairment by DNA hypomethylation of CYP2C19 gene in STEMI patients undergoing primary percutaneous coronary intervention (PPCI) |
2021 |
Pharmacology Research and Perspectives |
9 |
2 |
e00738 |
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2 |
https://www.scopus.com/inward/record.uri?eid=2-s2.0-85102225470&doi=10.1002%2fprp2.738&partnerID=40&md5=444f8c3e75e75ed786eedbe412614a0b |
Cardiology and Vascular Medicine Department, Faculty of Medicine Universitas Indonesia, National Cardiovascular Center Harapan Kita, Jakarta, Indonesia; Clinical Pathology Department, Faculty of Medicine Universitas Indonesia, Dr. Cipto Mangunkusumo National Public Hospital, Jakarta, Indonesia; Indonesian Cardiovascular Research Center, National Cardiovascular Center Harapan Kita, Jakarta, Indonesia |
Sukmawan, R., Cardiology and Vascular Medicine Department, Faculty of Medicine Universitas Indonesia, National Cardiovascular Center Harapan Kita, Jakarta, Indonesia; Hoetama, E., Cardiology and Vascular Medicine Department, Faculty of Medicine Universitas Indonesia, National Cardiovascular Center Harapan Kita, Jakarta, Indonesia; Suridanda Danny, S., Cardiology and Vascular Medicine Department, Faculty of Medicine Universitas Indonesia, National Cardiovascular Center Harapan Kita, Jakarta, Indonesia; Giantini, A., Clinical Pathology Department, Faculty of Medicine Universitas Indonesia, Dr. Cipto Mangunkusumo National Public Hospital, Jakarta, Indonesia; Listiyaningsih, E., Indonesian Cardiovascular Research Center, National Cardiovascular Center Harapan Kita, Jakarta, Indonesia; Gilang Rejeki, V., Cardiology and Vascular Medicine Department, Faculty of Medicine Universitas Indonesia, National Cardiovascular Center Harapan Kita, Jakarta, Indonesia; Aziz Alkatiri, A., Cardiology and Vascular Medicine Department, Faculty of Medicine Universitas Indonesia, National Cardiovascular Center Harapan Kita, Jakarta, Indonesia; Firdaus, I., Cardiology and Vascular Medicine Department, Faculty of Medicine Universitas Indonesia, National Cardiovascular Center Harapan Kita, Jakarta, Indonesia |
Clopidogrel resistance is an important risk factor of ischemic event recurrence after optimal antiplatelet therapy. This study aims to investigate the role of CYP2C19 gene DNA methylation as one of the epigenetic factors for the risk of clopidogrel resistance in STEMI patients undergoing PPCI. ST-segment elevation myocardial infarction (STEMI) patients undergoing PPCI were pretreated with clopidogrel, and their platelet function was measured using VerifyNow™ assay. The criteria for high on-treatment platelet reactivity (HPR) were defined according to the expert consensus criteria (PRU >208). DNA methylation of the CYP2C19 gene was performed using bisulfite genomic sequencing technology. Furthermore, clinical, laboratory, and angiographic data including TIMI flow were collected. Among 122 patients, clopidogrel resistance was found in 22%. DNA methylation level percentage was lower in the clopidogrel resistance group (76.7 vs. 88.8, p-value.038). But, the <50% methylation group was associated with increased risk of clopidogrel resistance (OR =4.5, 95%CI =2.1–9.3, p-value =.018). This group was also found to have suboptimal post-PCI TIMI flow (OR =3.4 95%CI =1.3–8.7, p-value =.045). The lower DNA methylation level of the CYP2C19 gene increases the risk of clopidogrel resistance and subsequent poorer clinical outcome. © 2021 The Authors. Pharmacology Research & Perspectives published by British Pharmacological Society and American Society for Pharmacology and Experimental Therapeutics and John Wiley & Sons Ltd. |
acute coronary syndrome; clopidogrel resistance; CYP2C19; DNA methylation |
acetylsalicylic acid; clopidogrel; cytochrome P450 2C19; clopidogrel; CYP2C19 protein, human; cytochrome P450 2C19; aged; angiography; blood clotting parameters; Cytochrome P450 2C19 gene; diabetes mellitus; DNA methylation; echocardiography; female; human; loading drug dose; major clinical study; male; percutaneous coronary intervention; Review; ST segment elevation myocardial infarction; adult; complication; drug effect; drug resistance; fibrinolytic therapy; genetics; metabolism; middle aged; percutaneous coronary intervention; procedures; recurrent disease; secondary prevention; ST segment elevation myocardial infarction; thrombocyte aggregation; Adult; Clopidogrel; Cytochrome P-450 CYP2C19; DNA Methylation; Drug Resistance; Female; Humans; Male; Middle Aged; Percutaneous Coronary Inte |
John Wiley and Sons Inc |
20521707 |
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33641235 |
Review |
Q1 |
975 |
4541 |
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482 |
Siste K., Wiguna T., Bardasono S., Sekartini R., Pandelaki J., Sarasvita R., Suwartono C., Murtani B.J., Damayanti R., Christian H., Sen L.T., Nasrun M.W. |
55644113100;24367785700;57222151719;57224503576;35759266900;50462352200;15078359800;57216652176;57215770702;57209266195;57219034101;57196216137; |
Internet addiction in adolescents: Development and validation of Internet Addiction Diagnostic Questionnaire (KDAI) |
2021 |
Psychiatry Research |
298 |
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113829 |
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2 |
https://www.scopus.com/inward/record.uri?eid=2-s2.0-85101721252&doi=10.1016%2fj.psychres.2021.113829&partnerID=40&md5=57d16e1d74c98eda3345bc1ba9eca18e |
Department of Psychiatry, Faculty of Medicine, Universitas Indonesia- dr. Cipto Mangunkusumo General Hospital, Jakarta, Indonesia; Department of Nutrition, Faculty of Medicine, Universitas Indonesia- dr. Cipto Mangunkusumo General Hospital, Jakarta, Indonesia; Department of Child Health, Faculty of Medicine, Universitas Indonesia- dr. Cipto Mangunkusumo General Hospital, Jakarta, Indonesia; Department of Radiology, Faculty of Medicine, Universitas Indonesia- dr. Cipto Mangunkusumo General Hospital, Jakarta, Indonesia; Indonesia National Narcotics Board, Jakarta, Indonesia; Department of Psychology, Soegijapranata Catholic University, Semarang, Central Java, Indonesia; Faculty of Psychology, Atma Jaya Catholic University of Indonesia, Jakarta, Indonesia |
Siste, K., Department of Psychiatry, Faculty of Medicine, Universitas Indonesia- dr. Cipto Mangunkusumo General Hospital, Jakarta, Indonesia; Wiguna, T., Department of Psychiatry, Faculty of Medicine, Universitas Indonesia- dr. Cipto Mangunkusumo General Hospital, Jakarta, Indonesia; Bardasono, S., Department of Nutrition, Faculty of Medicine, Universitas Indonesia- dr. Cipto Mangunkusumo General Hospital, Jakarta, Indonesia; Sekartini, R., Department of Child Health, Faculty of Medicine, Universitas Indonesia- dr. Cipto Mangunkusumo General Hospital, Jakarta, Indonesia; Pandelaki, J., Department of Radiology, Faculty of Medicine, Universitas Indonesia- dr. Cipto Mangunkusumo General Hospital, Jakarta, Indonesia; Sarasvita, R., Indonesia National Narcotics Board, Jakarta, Indonesia, Department of Psychology, Soegijapranata Catholic University, Semarang, Central Java, Indonesia; Suwartono, C., Faculty of Psychology, Atma Jaya Catholic University of Indonesia, Jakarta, Indonesia; Murtani, B.J., Department of Psychiatry, Faculty of Medicine, Universitas Indonesia- dr. Cipto Mangunkusumo General Hospital, Jakarta, Indonesia; Damayanti, R., Department of Psychiatry, Faculty of Medicine, Universitas Indonesia- dr. Cipto Mangunkusumo General Hospital, Jakarta, Indonesia; Christian, H., Department of Psychiatry, Faculty of Medicine, Universitas Indonesia- dr. Cipto Mangunkusumo General Hospital, Jakarta, Indonesia; Sen, L.T., Department of Psychiatry, Faculty of Medicine, Universitas Indonesia- dr. Cipto Mangunkusumo General Hospital, Jakarta, Indonesia; Nasrun, M.W., Department of Psychiatry, Faculty of Medicine, Universitas Indonesia- dr. Cipto Mangunkusumo General Hospital, Jakarta, Indonesia |
Internet addiction (IA) is an emerging behavioral problem that constitutes a major health threat to vulnerable populations, including adolescents. However, there is a paucity of IA screening tools specifically designed for adolescents, especially in Indonesia. Therefore, the current study developed and validated the IA Diagnostic Questionnaire (KDAI) in adolescents while acknowledging local cultural influences. The KDAI was conceived through extensive literature reviews, expert discussions based on Delphi methods, a face validity study, focus group discussion (N = 31) for initial reliability testing, and a recruited pilot study (N = 385) and main study (N = 643) for exploratory and confirmatory factor analyses, respectively. The multi-sample analyses demonstrated that the KDAI model with the best fit and reliability comprised a seven-factor structure, including withdrawal, loss of control, increase of priority, negative consequences, mood modification, salience, and impairment. These factors were scrutinized against domains of IA Test, and concurrent validity was ascertained. Subsequently, a receiver operating characteristic curve and area under the curve determined a cutoff score of 108 to discern adolescents with IA. Taken together, the KDAI displayed excellent psychometric indices and sensitivity as a screening tool for IA in adolescents. © 2021 |
Behavioral addiction; Psychometric characteristic; Screening instrument; Self-report |
adolescent; adult; Article; child; concurrent validity; confirmatory factor analysis; controlled study; cultural anthropology; Delphi study; diagnostic accuracy; diagnostic test accuracy study; exploratory research; face validity; female; human; internet addiction; Internet Addiction Diagnostic Questionnaire; major clinical study; male; mood; pilot study; psychometry; questionnaire; receiver operating characteristic; reference value; reliability; scoring system; self report; sensitivity and specificity; validation study; addiction; Internet; internet addiction; questionnaire; reproducibility; Adolescent; Behavior, Addictive; Humans; Internet; Internet Addiction Disorder; Pilot Projects; Reproducibility of Results; Surveys and Questionnaires |
Elsevier Ireland Ltd |
01651781 |
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33662841 |
Article |
Q1 |
1224 |
3201 |
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517 |
Anindyajati G., Wiguna T., Murtani B.J., Christian H., Wigantara N.A., Putra A.A., Hanafi E., Minayati K., Ismail R.I., Kaligis F., Savitri A.I., Uiterwaal C.S.P.M., Diatri H. |
57194606169;24367785700;57216652176;57209266195;57218679014;57220161382;56737010600;57218681686;55996895500;36604651700;56401804100;7006033434;36113389500; |
Anxiety and Its Associated Factors During the Initial Phase of the COVID-19 Pandemic in Indonesia |
2021 |
Frontiers in Psychiatry |
12 |
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634585 |
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2 |
https://www.scopus.com/inward/record.uri?eid=2-s2.0-85102995915&doi=10.3389%2ffpsyt.2021.634585&partnerID=40&md5=b28d0b2bafd0f4413cc6d469ba102a50 |
Department of Psychiatry, Faculty of Medicine, Universitas Indonesia—Cipto Mangunkusumo Hospital, Jakarta, Indonesia; The Center for Clinical Epidemiology and Evidence-Based Medicine Faculty of Medicine, Universitas Indonesia—Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Julius Global Health, Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Utrecht, Netherlands |
Anindyajati, G., Department of Psychiatry, Faculty of Medicine, Universitas Indonesia—Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Wiguna, T., Department of Psychiatry, Faculty of Medicine, Universitas Indonesia—Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Murtani, B.J., Department of Psychiatry, Faculty of Medicine, Universitas Indonesia—Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Christian, H., Department of Psychiatry, Faculty of Medicine, Universitas Indonesia—Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Wigantara, N.A., Department of Psychiatry, Faculty of Medicine, Universitas Indonesia—Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Putra, A.A., Department of Psychiatry, Faculty of Medicine, Universitas Indonesia—Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Hanafi, E., Department of Psychiatry, Faculty of Medicine, Universitas Indonesia—Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Minayati, K., Department of Psychiatry, Faculty of Medicine, Universitas Indonesia—Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Ismail, R.I., Department of Psychiatry, Faculty of Medicine, Universitas Indonesia—Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Kaligis, F., Department of Psychiatry, Faculty of Medicine, Universitas Indonesia—Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Savitri, A.I., The Center for Clinical Epidemiology and Evidence-Based Medicine Faculty of Medicine, Universitas Indonesia—Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Uiterwaal, C.S.P.M., Julius Global Health, Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Utrecht, Netherlands; Diatri, H., Department of Psychiatry, Faculty of Medicine, Universitas Indonesia—Cipto Mangunkusumo Hospital, Jakarta, Indonesia |
Introduction: Coronavirus disease 2019 (COVID-19) is caused by a novel coronavirus which has not been identified previously in humans. The disease leads to respiratory problems, systemic disorders, and death. To stop the virus transmission, physical distancing was strongly implemented, including working and school from home (WFH & SFH). The limitation altered daily routines and needs advanced to adapt. Many have felt uncomfortable and this could have triggered anxiety symptoms. This study aimed to evaluate the proportion of significant anxiety symptoms and its association with COVID-19-related situations in an Indonesian context during the initial months of the pandemic. Methods: An online community survey was distributed through social media and communication platforms, mainly WhatsApp, targeting people >18 years old in Indonesia. Anxiety symptoms were assessed using Generalized Anxiety Disorder-7 (Indonesian Version). Demographical data and information on social situation related to the COVID-19 pandemic were collected. The proportion of clinically significant anxiety symptoms was calculated and the association with demographic and social factors was assessed using chi square test (χ2) and logistic regression for multivariate analysis. Results: Out of 1215 subjects that completed the survey, 20.2% (n = 245) exhibited significant anxiety symptoms. Several factors, such as age (AOR = 0.933 CI 95% = 0.907–0.96), sex (AOR = 1.612 CI 95% = 1.097–2.369), medical workers (AOR = 0.209 CI 95% = 0.061–0.721), suspected case of COVID-19 (AOR = 1.786 CI 95% = 1.001–3.186), satisfaction level of family support (AOR = 3.052 CI 95% = 1.883–4.946), and satisfaction level of co-workers (AOR = 2.523 CI 95% = 1.395–4.562), were associated with anxiety. Conclusion: One out of five Indonesian people could have suffered from anxiety during the COVID-19 pandemic. The riskiest group being young females, people who had suspected cases of COVID-19, and those with less satisfying social support. Nevertheless, health workers were found to have a lesser risk of developing anxiety. Accessible information and healthcare, social connection, supportive environment, and mental health surveillance are important to prevent bigger psychiatric problems post-pandemic. © Copyright © 2021 Anindyajati, Wiguna, Murtani, Christian, Wigantara, Putra, Hanafi, Minayati, Ismail, Kaligis, Savitri, Uiterwaal and Diatri. |
anxiety; COVID-19 pandemic; Indonesian; mental health surveillance; psychosocial support |
adult; anxiety disorder; Article; controlled study; coronavirus disease 2019; disease association; female; generalized anxiety disorder; high risk population; human; Indonesia; major clinical study; male; mental health; pandemic; patient satisfaction; psychosocial care; risk assessment; risk factor; social support; support group |
Frontiers Media S.A. |
16640640 |
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Q1 |
1363 |
2668 |
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527 |
Supali T., Djuardi Y., Christian M., Iskandar E., Alfian R., Maylasari R., Destani Y., Lomiga A., Minggu D., Lew D., Bogus J., Weil G.J., Fischer P.U. |
6602742029;6507800820;57209806543;57202299885;57222748640;57222744651;57222743128;57205724071;57202307524;57196371851;57170558700;7007028568;23567680200; |
An open label, randomized clinical trial to compare the tolerability and efficacy of ivermectin plus diethylcarbamazine and albendazole vs. Diethylcarbamazine plus albendazole for treatment of brugian filariasis in Indonesia |
2021 |
PLoS Neglected Tropical Diseases |
15 |
3 |
e0009294 |
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2 |
https://www.scopus.com/inward/record.uri?eid=2-s2.0-85103946402&doi=10.1371%2fjournal.pntd.0009294&partnerID=40&md5=bf67e831adfbad446acbda06b08e12de |
Department of Parasitology, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Universitas Nusa Cendana, Kupang, Lasiana, Kelapa lima, Kota Kupang, Indonesia; Nusa Tenggara Timur Provincial Health Office, Oebobo, Kota Kupang, Nusa Tenggara Timur, Indonesia; Division of Biostatistics, Washington University School of Medicine, St. Louis, MO, United States; Infectious Diseases Division, Department of Medicine, Washington University School of Medicine, St. Louis, MO, United States |
Supali, T., Department of Parasitology, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Djuardi, Y., Department of Parasitology, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Christian, M., Department of Parasitology, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Iskandar, E., Department of Parasitology, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Alfian, R., Department of Parasitology, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Maylasari, R., Department of Parasitology, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Destani, Y., Department of Parasitology, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Lomiga, A., Universitas Nusa Cendana, Kupang, Lasiana, Kelapa lima, Kota Kupang, Indonesia; Minggu, D., Nusa Tenggara Timur Provincial Health Office, Oebobo, Kota Kupang, Nusa Tenggara Timur, Indonesia; Lew, D., Division of Biostatistics, Washington University School of Medicine, St. Louis, MO, United States; Bogus, J., Infectious Diseases Division, Department of Medicine, Washington University School of Medicine, St. Louis, MO, United States; Weil, G.J., Infectious Diseases Division, Department of Medicine, Washington University School of Medicine, St. Louis, MO, United States; Fischer, P.U., Infectious Diseases Division, Department of Medicine, Washington University School of Medicine, St. Louis, MO, United States |
Improved treatments for lymphatic filariasis (LF) could accelerate the global elimination program for this disease. A triple drug combination of the anti-filarial drugs ivermectin, diethyl-carbamazine (DEC) and albendazole (IDA) has been shown to be safe and effective for achieving sustained clearance of microfilariae (Mf) of the filarial parasite Wuchereria ban-crofti from human blood. However, the triple drug combination has not been previously been evaluated for treatment of brugian filariasis, which accounts for about 10% of the global LF burden. This hospital-based clinical trial compared the safety and efficacy of IDA with that of the standard treatment (DEC plus albendazole, DA) in persons with Brugia timori infections on Sumba island, Indonesia. Fifty-five asymptomatic persons with B. timori Mf were treated with either a single oral dose of IDA (28 subjects) or with DEC plus albendazole (DA, 27 sub-jects). Participants were actively monitored for adverse events (AE) for two days after treatment by nurses and physicians who were masked regarding treatment assignments. Passive monitoring was performed by clinical teams that visited participant’s home villages for an additional five days. Microfilaremia was assessed by membrane filtration of 1 ml night blood at baseline, at 24h and one year after treatment. IDA was more effective than DA for completely clearing Mf at 24 hours (25/28, 89% vs. 8/27, 30%, P < 0.001). By 12 months after treatment, only one of 27 IDA recipients had Mf in their blood (4%) vs. 10 of 25 (40%) in persons treated with DA (P = 0.002). Approximately 90% of participants had antibodies to recombinant filarial antigen BmR1 at baseline. Antibody prevalence decreased to approximately 30% in both treatment groups at 12 months. About 45% of persons in both treatment groups experienced AE such as fever, muscle aches, lower back, joint and abdominal pain. These were mostly mild and most common during the first two days after treatment. No participant experienced a severe or serious AE. This study showed that IDA was well-tolerated and significantly more effective for clearing B. timori Mf from the blood than DA. Larger studies should be performed to further assess the safety and efficacy of IDA as a mass drug administration regimen to eliminate brugian filariasis. © 2021 Supali et al. |
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albendazole; antifilarial agent; diethylcarbamazine; immunoglobulin G4; ivermectin; albendazole; antifilarial agent; diethylcarbamazine; ivermectin; protozoon antibody; abdominal pain; adult; antibody titer; arthralgia; Article; body mass; Brugia; Brugian filariasis; Burkholderia pseudomallei; combination drug therapy; controlled study; coughing; daily life activity; double blind procedure; dried blood spot testing; drowsiness; drug efficacy; drug safety; drug tolerability; female; fever; filariasis; follow up; gametocyte; headache; helminthiasis; human; Indonesia; leprosy; low back pain; lymphatic filariasis; major clinical study; male; mass drug administration; microfilariasis; myalgia; pharmacokinetics; Plasmodium falciparum; prevalence; questionnaire; randomized controlled trial; Schis |
Public Library of Science |
19352727 |
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33780481 |
Article |
Q1 |
1990 |
1322 |
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529 |
Kario K., Hoshide S., Chia Y.-C., Buranakitjaroen P., Siddique S., Shin J., Turana Y., Park S., Tsoi K., Chen C.-H., Cheng H.-M., Fujiwara T., Li Y., Huynh V.M., Nagai M., Nailes J., Sison J., Soenarta A.A., Sogunuru G.P., Sukonthasarn A., Tay J.C., Teo B.W., Verma N., Wang T.-D., Zhang Y., Wang J.-G. |
7102633390;6603859769;57204080905;6603376248;57210091066;54791393300;56083326000;8556278400;16065259000;7501963868;57026688600;57212076752;55931488300;57222327024;23498874000;57204676117;36764809200;6507634613;26428524900;12793132900;24330212600;23570166200;7102496979;7405566618;56183109800;57211730247; |
Guidance on ambulatory blood pressure monitoring: A statement from the HOPE Asia Network |
2021 |
Journal of Clinical Hypertension |
23 |
3 |
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411 |
421 |
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2 |
https://www.scopus.com/inward/record.uri?eid=2-s2.0-85103146577&doi=10.1111%2fjch.14128&partnerID=40&md5=d75ac783dd0b799133a4ba32d9d8a571 |
Division of Cardiovascular Medicine, Department of Medicine, Jichi Medical University School of Medicine, Tochigi, Japan; Department of Medical Sciences, School of Healthcare and Medical Sciences, Sunway University, Bandar Sunway, Malaysia; Department of Primary Care Medicine, Faculty of Medicine, University of Malaya Kuala, Lumpur, Malaysia; Division of Hypertension, Department of Medicine, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand; Punjab Medical Center, Lahore, Pakistan; Faculty of Cardiology Service, Hanyang University Medical Center, Seoul, South Korea; School of Medicine and Health Sciences, Atma Jaya Catholic University of Indonesia, Jakarta, Indonesia; Division of Cardiology, Cardiovascular Hospital, Yonsei Health System, Seoul, South Korea; JC School of Public Health and Primary Care, The Chinese University of Hong Kong, Shatin, Hong Kong; Institute of Public Health and Community Medicine Research Center, National Yang-Ming University School of Medicine, Taipei, Taiwan; Division of Cardiology, Department of Medicine, Taipei Veterans General Hospital, Taipei, Taiwan; Faculty of Medicine, National Yang-Ming University School of Medicine, Taipei, Taiwan; Center for Evidence-based Medicine, Department of Medical Education, Taipei Veterans General Hospital, Taipei, Taiwan; Centre for Epidemiological Studies and Clinical Trials and Center for Vascular Evaluations, Shanghai Key Lab of Hypertension, Shanghai Institute of Hypertension, Ruijin Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, China; Department of Internal Medicine, University of Medicine and Pharmacy, Hue University, Viet Nam; Department of Internal Medicine, General Medicine and Cardiology, Hiroshima City Asa Hospital, Hiroshima, Japan; Department of Preventive and Community Medicine and Research Institute for Health Sciences, University of the East Ramon Magsaysay Memorial Medical Center Inc, Quezon City, Philippines; Section of Cardiology, Department of Medicine, Medical Center Manila, Manila, Philippines; Department of Cardiology and Vascular Medicine, Faculty of Medicine, University of Indonesia-National Cardiovascular Center, Harapan Kita, Jakarta, Indonesia; MIOT International Hospital, Chennai, India; College of Medical Sciences, Kathmandu University, Bharatpur, Nepal; Cardiology Division, Department of Internal Medicine, Faculty of Medicine, Chiang Mai University, Thailand; Department of General Medicine, Tan Tock Seng Hospital, Singapore, Singapore; Division of Nephrology Department of Medicine, Yong Loo Lin School of Medicine, Singapore, Singapore; Department of Physiology, King George's Medical University, Lucknow, India; Cardiovascular Center and Division of Cardiology, Department of Internal Medicine, National Taiwan University Hospital, Taipei City, Taiwan; National Taiwan University Hospital, Taipei City, Taiwan; Division of Hospital Medicine, Department of Internal Medicine, National Taiwan University Hospital, Taipei City, Taiwan; Divisions of Hypertension and Heart Failure, Fu Wai Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China; Department of Hypertension, Centre for Epidemiological Studies and Clinical Trials, the Shanghai Institute of Hypertension, Shanghai Key Laboratory of Hypertension, Ruijin Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, China |
Kario, K., Division of Cardiovascular Medicine, Department of Medicine, Jichi Medical University School of Medicine, Tochigi, Japan; Hoshide, S., Division of Cardiovascular Medicine, Department of Medicine, Jichi Medical University School of Medicine, Tochigi, Japan; Chia, Y.-C., Department of Medical Sciences, School of Healthcare and Medical Sciences, Sunway University, Bandar Sunway, Malaysia, Department of Primary Care Medicine, Faculty of Medicine, University of Malaya Kuala, Lumpur, Malaysia; Buranakitjaroen, P., Division of Hypertension, Department of Medicine, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand; Siddique, S., Punjab Medical Center, Lahore, Pakistan; Shin, J., Faculty of Cardiology Service, Hanyang University Medical Center, Seoul, South Korea; Turana, Y., School of Medicine and Health Sciences, Atma Jaya Catholic University of Indonesia, Jakarta, Indonesia; Park, S., Division of Cardiology, Cardiovascular Hospital, Yonsei Health System, Seoul, South Korea; Tsoi, K., JC School of Public Health and Primary Care, The Chinese University of Hong Kong, Shatin, Hong Kong; Chen, C.-H., Institute of Public Health and Community Medicine Research Center, National Yang-Ming University School of Medicine, Taipei, Taiwan, Division of Cardiology, Department of Medicine, Taipei Veterans General Hospital, Taipei, Taiwan, Faculty of Medicine, National Yang-Ming University School of Medicine, Taipei, Taiwan; Cheng, H.-M., Institute of Public Health and Community Medicine Research Center, National Yang-Ming University School of Medicine, Taipei, Taiwan, Division of Cardiology, Department of Medicine, Taipei Veterans General Hospital, Taipei, Taiwan, Faculty of Medicine, National Yang-Ming University School of Medicine, Taipei, Taiwan, Center for Evidence-based Medicine, Department of Medical Education, Taipei Veterans General Hospital, Taipei, Taiwan; Fujiwara, T., Division of Cardiovascular Medicine, Department of Medicine, Jichi Medical University School of Medicine, Tochigi, Japan; Li, Y., Centre for Epidemiological Studies and Clinical Trials and Center for Vascular Evaluations, Shanghai Key Lab of Hypertension, Shanghai Institute of Hypertension, Ruijin Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, China; Huynh, V.M., Department of Internal Medicine, University of Medicine and Pharmacy, Hue University, Viet Nam; Nagai, M., Department of Internal Medicine, General Medicine and Cardiology, Hiroshima City Asa Hospital, Hiroshima, Japan; Nailes, J., Department of Preventive and Community Medicine and Research Institute for Health Sciences, University of the East Ramon Magsaysay Memorial Medical Center Inc, Quezon City, Philippines; Sison, J., Section of Cardiology, Department of Medicine, Medical Center Manila, Manila, Philippines; Soenarta, A.A., Department of Cardiology and Vascular Medicine, Faculty of Medicine, University of Indonesia-National Cardiovascular Center, Harapan Kita, Jakarta, Indonesia; Sogunuru, G.P., MIOT International Hospital, Chennai, India, College of Medical Sciences, Kathmandu University, Bharatpur, Nepal; Sukonthasarn, A., Cardiology Division, Department of Internal Medicine, Faculty of Medicine, Chiang Mai University, Thailand; Tay, J.C., Department of General Medicine, Tan Tock Seng Hospital, Singapore, Singapore; Teo, B.W., Division of Nephrology Department of Medicine, Yong Loo Lin School of Medicine, Singapore, Singapore; Verma, N., Department of Physiology, King George's Medical University, Lucknow, India; Wang, T.-D., Cardiovascular Center and Division of Cardiology, Department of Internal Medicine, National Taiwan University Hospital, Taipei City, Taiwan, National Taiwan University Hospital, Taipei City, Taiwan, Division of Hospital Medicine, Department of Internal Medicine, National Taiwan University Hospital, Taipei City, Taiwan; Zhang, Y., Divisions of Hypertension and Heart Failure, Fu Wai Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China; Wang, J.-G., Department of Hypertension, Centre for Epidemiological Studies and Clinical Trials, the Shanghai Institute of Hypertension, Shanghai Key Laboratory of Hypertension, Ruijin Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, China |
Hypertension is an important public health issue due to its association with a number of serious diseases, including cardiovascular disease and stroke. The importance of evaluating hypertension taking into account different blood pressure (BP) profiles and BP variability (BPV) is increasingly being recognized, and is particularly relevant in Asian populations given the specific features of hypertension in the region (including greater salt sensitivity and a high rate of nocturnal hypertension). Ambulatory BP monitoring (ABPM) is the gold standard for diagnosing hypertension and assessing 24-hour BP and provides data on several important parameters that cannot be obtained using any other form of BP measurement. In addition, ABPM parameters provide better information on cardio- and cerebrovascular risk than office BP. ABPM should be used in all patients with elevated BP, particularly those with unstable office or home BP, or who are suspected to have white-coat or masked hypertension. ABPM is also an important part of hypertension diagnosis and monitoring in high-risk patients. ABPM needs to be performed using a validated device and good practice techniques, and has a role both in hypertension diagnosis and in monitoring the response to antihypertensive therapy to ensure strict BP control throughout the 24-hour period. Use of ABPM in clinical practice may be limited by cost and accessibility, and practical education of physicians and patients is essential. The ABPM evidence and practice points in this document are based on the Hypertension Cardiovascular Outcome Prevention and Evidence (HOPE) Asia Network expert panel consensus recommendations for ABPM in Asia. © 2020 The Authors. The Journal of Clinical Hypertension published by Wiley Periodicals LLC |
ambulatory blood pressure monitoring; blood pressure control; clinical practice; guidelines; hypertension |
angiotensin receptor antagonist; antihypertensive agent; calcium channel blocking agent; dipeptidyl carboxypeptidase inhibitor; antihypertensive agent; atherosclerosis; blood pressure monitoring; blood pressure regulation; blood pressure variability; brain hemorrhage; cardiovascular risk; circadian rhythm; cognitive defect; comorbidity; coronary artery disease; cost control; diastolic blood pressure; diastolic dysfunction; disease association; drug efficacy; health care access; heart left ventricle hypertrophy; high risk patient; human; low risk patient; masked hypertension; microangiopathy; prevalence; prognosis; reimbursement; Review; sensitivity and specificity; sleep disordered breathing; systolic blood pressure; telemedicine; treatment response; white coat hypertension; Asia; blood pr |
John Wiley and Sons Inc |
15246175 |
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33319412 |
Review |
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909 |
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Hoshide S., Kario K., Chia Y.-C., Siddique S., Buranakitjaroen P., Tsoi K., Tay J.C., Turana Y., Chen C.-H., Cheng H.-M., Huynh V.M., Park S., Soenarta A.A., Sogunuru G.P., Wang T.-D., Wang J.-G. |
6603859769;7102633390;57204080905;57210091066;6603376248;16065259000;24330212600;56083326000;7501963868;57026688600;57222327024;8556278400;6507634613;26428524900;7405566618;57211730247; |
Characteristics of hypertension in obstructive sleep apnea: An Asian experience |
2021 |
Journal of Clinical Hypertension |
23 |
3 |
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489 |
495 |
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2 |
https://www.scopus.com/inward/record.uri?eid=2-s2.0-85102268392&doi=10.1111%2fjch.14184&partnerID=40&md5=801bd49c61521ab9e90707d5d59d804b |
Division of Cardiovascular Medicine, Department of Medicine, Jichi Medical University School of Medicine, Tochigi, Japan; Department of Medical Sciences, School of Healthcare and Medical Sciences, Sunway University, Bandar Sunway, Malaysia; Department of Primary Care Medicine, Faculty of Medicine, University of Malaya Kuala, Lumpur, Malaysia; Punjab Medical Center, Lahore, Pakistan; Division of Hypertension, Department of Medicine, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand; JC School of Public Health and Primary Care, The Chinese University of Hong Kong, Shatin, Hong Kong; Department of General Medicine, Tan Tock Seng Hospital, Singapore City, Singapore; School of Medicine and Health Sciences, Atma Jaya Catholic University of Indonesia, Jakarta, Indonesia; Institute of Public Health and Community Medicine Research Center, National Yang-Ming University School of Medicine, Taipei, Taiwan; Division of Cardiology, Department of Medicine, Taipei Veterans General Hospital, Taipei, Taiwan; Faculty of Medicine, National Yang-Ming University School of Medicine, Taipei, Taiwan; Department of Medical Education, Center for Evidence-based Medicine, Taipei Veterans General Hospital, Taipei, Taiwan; Department of Internal Medicine, University of Medicine and Pharmacy, Hue University, Viet Nam; Division of Cardiology, Cardiovascular Hospital, Yonsei Health System, Seoul, South Korea; Department of Cardiology and Vascular Medicine, Faculty of Medicine, University of Indonesia-National Cardiovascular Center, Jakarta, Indonesia; MIOT International Hospital, Chennai, India; College of Medical Sciences, Kathmandu University, Bharatpur, Nepal; Cardiovascular Center and Division of Cardiology, Department of Internal Medicine, National Taiwan University Hospital, Taipei City, Taiwan; Division of Hospital Medicine, Department of Internal Medicine, National Taiwan University Hospital, Taipei City, Taiwan; Department of Hypertension, Shanghai Key Laboratory of Hypertension, Centre for Epidemiological Studies and Clinical Trials, The Shanghai Institute of Hypertension, Ruijin Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, China |
Hoshide, S., Division of Cardiovascular Medicine, Department of Medicine, Jichi Medical University School of Medicine, Tochigi, Japan; Kario, K., Division of Cardiovascular Medicine, Department of Medicine, Jichi Medical University School of Medicine, Tochigi, Japan; Chia, Y.-C., Department of Medical Sciences, School of Healthcare and Medical Sciences, Sunway University, Bandar Sunway, Malaysia, Department of Primary Care Medicine, Faculty of Medicine, University of Malaya Kuala, Lumpur, Malaysia; Siddique, S., Punjab Medical Center, Lahore, Pakistan; Buranakitjaroen, P., Division of Hypertension, Department of Medicine, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand; Tsoi, K., JC School of Public Health and Primary Care, The Chinese University of Hong Kong, Shatin, Hong Kong; Tay, J.C., Department of General Medicine, Tan Tock Seng Hospital, Singapore City, Singapore; Turana, Y., School of Medicine and Health Sciences, Atma Jaya Catholic University of Indonesia, Jakarta, Indonesia; Chen, C.-H., Institute of Public Health and Community Medicine Research Center, National Yang-Ming University School of Medicine, Taipei, Taiwan, Division of Cardiology, Department of Medicine, Taipei Veterans General Hospital, Taipei, Taiwan, Faculty of Medicine, National Yang-Ming University School of Medicine, Taipei, Taiwan; Cheng, H.-M., Institute of Public Health and Community Medicine Research Center, National Yang-Ming University School of Medicine, Taipei, Taiwan, Division of Cardiology, Department of Medicine, Taipei Veterans General Hospital, Taipei, Taiwan, Faculty of Medicine, National Yang-Ming University School of Medicine, Taipei, Taiwan, Department of Medical Education, Center for Evidence-based Medicine, Taipei Veterans General Hospital, Taipei, Taiwan; Huynh, V.M., Department of Internal Medicine, University of Medicine and Pharmacy, Hue University, Viet Nam; Park, S., Division of Cardiology, Cardiovascular Hospital, Yonsei Health System, Seoul, South Korea; Soenarta, A.A., Department of Cardiology and Vascular Medicine, Faculty of Medicine, University of Indonesia-National Cardiovascular Center, Jakarta, Indonesia; Sogunuru, G.P., MIOT International Hospital, Chennai, India, College of Medical Sciences, Kathmandu University, Bharatpur, Nepal; Wang, T.-D., Cardiovascular Center and Division of Cardiology, Department of Internal Medicine, National Taiwan University Hospital, Taipei City, Taiwan, Division of Hospital Medicine, Department of Internal Medicine, National Taiwan University Hospital, Taipei City, Taiwan; Wang, J.-G., Department of Hypertension, Shanghai Key Laboratory of Hypertension, Centre for Epidemiological Studies and Clinical Trials, The Shanghai Institute of Hypertension, Ruijin Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, China |
Obstructive sleep apnea (OSA) is a risk of hypertension and is associated with cardiovascular disease (CVD) incidence. In Asian countries, the prevalence of OSA is high, as in Western countries. When blood pressure (BP) is evaluated in OSA individuals using ambulatory BP monitoring (ABPM), the BP phenotype often indicates abnormal BP variability, such as increased nighttime BP or abnormal diurnal BP variation, that is, non-dipper pattern, riser pattern, and morning BP surge, and all these conditions have been associated with increased CVD events. Asians have a higher prevalence of increased nighttime BP or morning BP surge than Westerners. Therefore, this review paper focused on OSA and hypertension from an Asian perspective to investigate the importance of the association between OSA and hypertension in the Asian population. Such abnormal BP variability has been shown to be associated with progression of arterial stiffness, and this association could provoke a vicious cycle between abnormal BP phenotypes and arterial stiffness, a phenomenon recognized as systemic hemodynamic atherothrombotic syndrome (SHATS). OSA may be one of the background factors that augment SHATS. An oxygen-triggered nocturnal oscillometric BP measurement device combined with a pulse oximeter for continuous SpO2 monitoring could detect BP variability caused by OSA. In addition to treating the OSA, accurate and reliable detection and treatment of any residual BP elevation and BP variability caused by OSA would be necessary to prevent CVD events. However, more detailed detection of BP variability, such as beat-by-beat BP monitoring, would further help to reduce CV events. © 2021 The Authors. The Journal of Clinical Hypertension published by Wiley Periodicals LLC. |
blood pressure variability; hypertension; obstructive sleep apnea |
amlodipine; antihypertensive agent; atenolol; enalapril; hydrochlorothiazide; losartan; aerobic exercise; antihypertensive therapy; apnea hypopnea index; Asia; Asian; blood pressure; body mass; continuous positive airway pressure; follow up; human; hypertension; kidney denervation; lifestyle modification; obesity; polysomnography; primary hyperaldosteronism; Review; sleep disordered breathing; Asian continental ancestry group; blood pressure monitoring; hypertension; sleep disordered breathing; Asia; Asian Continental Ancestry Group; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Humans; Hypertension; Sleep Apnea, Obstructive |
John Wiley and Sons Inc |
15246175 |
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33705599 |
Review |
Q2 |
909 |
5078 |
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540 |
Chia Y.-C., Turana Y., Sukonthasarn A., Zhang Y., Shin J., Cheng H.-M., Tay J.C., Tsoi K., Siddique S., Verma N., Buranakitjaroen P., Sogunuru G.P., Nailes J., Van Minh H., Park S., Teo B.W., Chen C.-H., Wang T.-D., Soenarta A.A., Hoshide S., Wang J.-G., Kario K., the Hypertension Cardiovascular Outcome Prevention, Evidence (HOPE) Asia Network |
57204080905;56083326000;12793132900;56183109800;54791393300;57026688600;24330212600;16065259000;57210091066;7102496979;6603376248;26428524900;57204676117;57211946145;8556278400;23570166200;7501963868;7405566618;6507634613;6603859769;57211730247;7102633390; |
Comparison of guidelines for the management of hypertension: Similarities and differences between international and Asian countries; perspectives from HOPE-Asia Network |
2021 |
Journal of Clinical Hypertension |
23 |
3 |
|
422 |
434 |
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2 |
https://www.scopus.com/inward/record.uri?eid=2-s2.0-85101598138&doi=10.1111%2fjch.14226&partnerID=40&md5=3615334261cf54af8eb6d23b4967e99b |
Department of Medical Sciences, School of Medical and Life Sciences, Sunway University, Bandar Sunway, Malaysia; Department of Primary Care Medicine, Faculty of Medicine, University of Malaya Kuala, Lumpur, Malaysia; School of Medicine and Health Sciences, Atma Jaya Catholic University of Indonesia, Jakarta, Indonesia; Cardiology Division, Department of Internal Medicine, Faculty of Medicine, Chiang Mai University, Chiang Mai, Thailand; Division of Hypertension and Heart Failure, Fu Wai Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China; Faculty of Cardiology Service, Hanyang University Medical Center, Seoul, South Korea; Institute of Public Health and Community Medicine Research Center, National Yang-Ming University School of Medicine, Taipei, Taiwan; Division of Cardiology, Department of Medicine, Taipei Veterans General Hospital, Taipei, Taiwan; Faculty of Medicine, National Yang-Ming University School of Medicine, Taipei, Taiwan; Center for Evidence-Based Medicine, Department of Medical Education, Taipei Veterans General Hospital, Taipei, Taiwan; Department of General Medicine, Tan Tock Seng Hospital, Singapore; JC School of Public Health and Primary Care, The Chinese University of Hong Kong, Shatin, Hong Kong; Punjab Medical Center, Lahore, Pakistan; Department of Physiology, King George's Medical University, Lucknow, India; Division of Hypertension, Department of Medicine, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand; MIOT International Hospital, Chennai, India; College of Medical Sciences, Kathmandu University, Bharatpur, Nepal; University of the East Ramon Magsaysay Memorial Medical Center Inc., Quezon City, Philippines; Department of Internal Medicine, University of Medicine and Pharmacy, Hue University, Hue, Viet Nam; Division of Cardiology, Cardiovascular Hospital, Yonsei Health System, Seoul, South Korea; Division of Nephrology Department of Medicine, Yong Loo Lin School of Medicine, Singapore; Cardiovascular Center and Division of Cardiology, Department of Internal Medicine, National Taiwan University Hospital, Taipei City, Taiwan; Division of Hospital Medicine, Department of Internal Medicine, National Taiwan University Hospital, Taipei City, Taiwan; Department of Cardiology and Vascular Medicine, Faculty of Medicine, University of Indonesia-National Cardiovascular Center, Jakarta, Indonesia; Division of Cardiovascular Medicine, Department of Medicine, Jichi Medical University School of Medicine, Tochigi, Japan; Department of Hypertension, Centre for Epidemiological Studies and Clinical Trials, The Shanghai Institute of Hypertension, Shanghai Key Laboratory of Hypertension, Ruijin Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, China |
Chia, Y.-C., Department of Medical Sciences, School of Medical and Life Sciences, Sunway University, Bandar Sunway, Malaysia, Department of Primary Care Medicine, Faculty of Medicine, University of Malaya Kuala, Lumpur, Malaysia; Turana, Y., School of Medicine and Health Sciences, Atma Jaya Catholic University of Indonesia, Jakarta, Indonesia; Sukonthasarn, A., Cardiology Division, Department of Internal Medicine, Faculty of Medicine, Chiang Mai University, Chiang Mai, Thailand; Zhang, Y., Division of Hypertension and Heart Failure, Fu Wai Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China; Shin, J., Faculty of Cardiology Service, Hanyang University Medical Center, Seoul, South Korea; Cheng, H.-M., Institute of Public Health and Community Medicine Research Center, National Yang-Ming University School of Medicine, Taipei, Taiwan, Division of Cardiology, Department of Medicine, Taipei Veterans General Hospital, Taipei, Taiwan, Faculty of Medicine, National Yang-Ming University School of Medicine, Taipei, Taiwan, Center for Evidence-Based Medicine, Department of Medical Education, Taipei Veterans General Hospital, Taipei, Taiwan; Tay, J.C., Department of General Medicine, Tan Tock Seng Hospital, Singapore; Tsoi, K., JC School of Public Health and Primary Care, The Chinese University of Hong Kong, Shatin, Hong Kong; Siddique, S., Punjab Medical Center, Lahore, Pakistan; Verma, N., Department of Physiology, King George's Medical University, Lucknow, India; Buranakitjaroen, P., Division of Hypertension, Department of Medicine, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand; Sogunuru, G.P., MIOT International Hospital, Chennai, India, College of Medical Sciences, Kathmandu University, Bharatpur, Nepal; Nailes, J., University of the East Ramon Magsaysay Memorial Medical Center Inc., Quezon City, Philippines; Van Minh, H., Department of Internal Medicine, University of Medicine and Pharmacy, Hue University, Hue, Viet Nam; Park, S., Division of Cardiology, Cardiovascular Hospital, Yonsei Health System, Seoul, South Korea; Teo, B.W., Division of Nephrology Department of Medicine, Yong Loo Lin School of Medicine, Singapore; Chen, C.-H., Faculty of Medicine, National Yang-Ming University School of Medicine, Taipei, Taiwan, Center for Evidence-Based Medicine, Department of Medical Education, Taipei Veterans General Hospital, Taipei, Taiwan; Wang, T.-D., Cardiovascular Center and Division of Cardiology, Department of Internal Medicine, National Taiwan University Hospital, Taipei City, Taiwan, Division of Hospital Medicine, Department of Internal Medicine, National Taiwan University Hospital, Taipei City, Taiwan; Soenarta, A.A., Department of Cardiology and Vascular Medicine, Faculty of Medicine, University of Indonesia-National Cardiovascular Center, Jakarta, Indonesia; Hoshide, S., Division of Cardiovascular Medicine, Department of Medicine, Jichi Medical University School of Medicine, Tochigi, Japan; Wang, J.-G., Department of Hypertension, Centre for Epidemiological Studies and Clinical Trials, The Shanghai Institute of Hypertension, Shanghai Key Laboratory of Hypertension, Ruijin Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, China; Kario, K., Division of Cardiovascular Medicine, Department of Medicine, Jichi Medical University School of Medicine, Tochigi, Japan; the Hypertension Cardiovascular Outcome Prevention, Evidence (HOPE) Asia Network |
Guidelines on the management of hypertension have been developed by various professional bodies and institutions to primarily address the issues of diagnosis, treatment, and control in order to rationalize and improve the management of hypertension. Hypertension guidelines across the world have recently been updated following the new and controversial lower blood pressure threshold of ≥130/80 mmHg for the diagnosis of hypertension adopted by the Americans. While there are differences between the major as well as between the Asian national guidelines, there were also many similarities. This paper discusses and highlights the differences and similarities between the major international guidelines of the American College of Cardiology/American Heart Association, of the European Society of Cardiology/European Society of Hypertension, and of the International Society of Hypertension and also compares them with the Asian guidelines. © 2021 The Authors. The Journal of Clinical Hypertension published by Wiley Periodicals LLC. |
Asian countries; diagnosis; guidelines; HOPE-Asia Network; hypertension; target blood pressure |
angiotensin receptor antagonist; beta adrenergic receptor blocking agent; calcium channel blocking agent; dipeptidyl carboxypeptidase inhibitor; diuretic agent; Asia; blood pressure measurement; blood pressure monitoring; cardiovascular risk; cerebrovascular accident; chronic kidney failure; chronology; coronary artery disease; decision making; diabetes mellitus; Europe; geographic distribution; geriatrics; heart failure; Hong Kong; human; hypertension; India; Indonesia; Malaysia; medical society; multiple sclerosis; Pakistan; Philippines; practice guideline; Review; risk assessment; Singapore; Taiwan; Thailand; United States; Viet Nam; blood pressure; cardiology; hypertension; hypotension; American Heart Association; Asia; Blood Pressure; Cardiology; Humans; Hypertension; Hypotension; Uni |
John Wiley and Sons Inc |
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33634570 |
Review |
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Elvira S.D., Lamuri A., Lukman P.R., Malik K., Shatri H., Abdullah M. |
57192888533;57222088387;55981460300;57204114533;28767986500;7103393434; |
Psychological distress among Greater Jakarta area residents during the COVID-19 pandemic and community containment |
2021 |
Heliyon |
7 |
2 |
e06289 |
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2 |
https://www.scopus.com/inward/record.uri?eid=2-s2.0-85101376515&doi=10.1016%2fj.heliyon.2021.e06289&partnerID=40&md5=f6aaf6a6409201040c1d9b4f477052ca |
Department of Psychiatry, Faculty of Medicine, Universitas Indonesia, Indonesia; Indonesia Medical Education and Research Institute, Indonesia; Department of Internal Medicine, Faculty of Medicine Universitas Indonesia, Indonesia |
Elvira, S.D., Department of Psychiatry, Faculty of Medicine, Universitas Indonesia, Indonesia; Lamuri, A., Indonesia Medical Education and Research Institute, Indonesia; Lukman, P.R., Department of Psychiatry, Faculty of Medicine, Universitas Indonesia, Indonesia; Malik, K., Department of Psychiatry, Faculty of Medicine, Universitas Indonesia, Indonesia; Shatri, H., Department of Internal Medicine, Faculty of Medicine Universitas Indonesia, Indonesia; Abdullah, M., Department of Internal Medicine, Faculty of Medicine Universitas Indonesia, Indonesia |
Community quarantine; COVID-19; DASS-21; Psychological distress © 2021 The AuthorsIntroduction: Coronavirus disease 2019 (COVID-19) is an emerging pandemic affecting the global population. Community-based quarantine can slow down the pandemic growth while adversely affecting population-wide psychological well-being. Affected psychological well-being could potentially influence population compliance in following stipulated community quarantine procedures. Aim: The aim was to quantify psychological distress among Greater Jakarta area residents during the community containment period. Objectives: The objective was to measure depression, anxiety, and stress levels using the Indonesian version of the DASS-21. Demographic data on sex, education strata, and working/productive-age group were also collected. Methods: This cross-sectional observational analytic study employed an online questionnaire involving participants acquired through snowball sampling. The questionnaire comprises two parts: demographic data and psychological distress indicators. Linear regression evaluated psychological distress as a response variable. Results: Among 1,205 women and 824 men, our findings suggested male sex, age in the range of 15-24 years, and having a bachelor's degree or professional qualification have a strong association with psychological distress. Conclusion: By addressing the population at risk, policymakers can identify better countermeasures for preventing psychological distress. © 2021 The Authors |
Community quarantine; COVID-19; DASS-21; Psychological distress |
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Elsevier Ltd |
24058440 |
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Article |
Q1 |
455 |
10919 |
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