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Riset dan Pengabdian Masyarakat Do Research Sosial Service and Innovation

Id	Authors	Author S Id	Title	Year	Source Title	Volume	Issue	Page Start	Page End	Cited By	Link	Affiliations	Authors With Affiliations	Abstract	Author Keywords	Index Keywords	Publisher	Issn	Pubmed Id	Document Type	Sjr Best Quartile	Sjr	Sjr Rank
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869	Fabiani H., Mudjihartini N., Lestari W.	57222097497;57191055759;57222081857;	Dietary Omega-6 to Omega-3 Fatty Acids Ratio is Correlated with High Molecular Weight Adiponectin Level in Indonesian Office Workers	2021	International Journal of Nutrition, Pharmacology, Neurological Diseases	11	1	64	70	1	https://www.scopus.com/inward/record.uri?eid=2-s2.0-85101380278&doi=10.4103%2fijnpnd.ijnpnd-89-20&partnerID=40&md5=7be1b049e89a83256f279f76e4645583	Department of Nutrition, Faculty of Medicine, University of Indonesia, Jakarta, Indonesia; Department of Nutrition, Faculty of Medicine and Health Sciences, Krida Wacana Christian University, Jakarta, Indonesia; 3Department of Biochemistry and Molecular Biology, Faculty of Medicine, University of Indonesia, Jakarta, Indonesia	Fabiani, H., Department of Nutrition, Faculty of Medicine, University of Indonesia, Jakarta, Indonesia, Department of Nutrition, Faculty of Medicine and Health Sciences, Krida Wacana Christian University, Jakarta, Indonesia; Mudjihartini, N., 3Department of Biochemistry and Molecular Biology, Faculty of Medicine, University of Indonesia, Jakarta, Indonesia; Lestari, W., Department of Nutrition, Faculty of Medicine, University of Indonesia, Jakarta, Indonesia	Context: Adiponectin is an adipokine that is secreted by adipocytes and acts to prevent obesity and obesity-related disorders. The high ratio of omega-6 to omega-3 fatty acids in modern dietary habits in working-Age populations, urban areas in particular, is known to play a role in adiponectin secretion. However, previous studies showed inconclusive results. Aim: The study aims to determine the association of the dietary omega-6 to omega-3 fatty acids ratio with adiponectin levels in office workers in Jakarta, Indonesia. Settings and Design: This cross-sectional study included 55 office workers in East Jakarta, Indonesia. Methods: Data were collected via questionnaire, 3-day food record, anthropometric measurement, and serum collection. Statistical analysis used: Independent t test was applied to assess the relationship between subjects characteristics and dietary intake with high molecular weight adiponectin levels. Association of dietary omega-6/omega-3 fatty acids ratio and adiponectin were evaluated using Pearson correlation test (P < 0.05). Results: There is no statistically significant difference in adiponectin levels based on waist circumference category, as well as categories of physical activity, household income levels, total energy, and total fat intake. Conversely, in female subjects (P = 0.000), subjects with normal body mass index (P = 0.000), higher education levels (P = 0.031), and nonsmoking subjects (P = 0.019), significantly higher adiponectin levels are obtained. The ratio of dietary omega-6/omega-3 fatty acids is negatively correlated with adiponectin (P = 0.004, r =-0.383). Conclusions: The decrease in the ratio of omega-6/omega-3 fatty acids is inversely related to higher level of adiponectin, indicating that dietary changes may potentially play a role in prevention strategies for obesity and obesity-related diseases. © 2021 Wolters Kluwer Medknow Publications. All rights reserved.	HMW adiponectin; obesity; omega-3 fatty acid; omega-6 fatty acid; workers	adiponectin; omega 3 fatty acid; omega 6 fatty acid; adult; Article; body mass; caloric intake; cross-sectional study; cytokine release; data analysis software; dietary intake; educational status; fat intake; female; food frequency questionnaire; household income; human; Indonesia; male; metabolic equivalent; molecular weight; non-smoker; obesity; office worker; physical activity; protein expression; sex difference; waist circumference	Wolters Kluwer Medknow Publications	22310738		Article	Q4	177	20903	View
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344	Susantiningsih T., Makkiyah F.A., Thadeus M.S., Yulianti R., Hadi S.	57192907038;57210232162;57226238484;57201696813;26534077400;	Progressive acute liver damage induced by repeated 2-nitropropane: Focused on obese mice	2021	Biomedical and Pharmacology Journal	14	2	695	700		https://www.scopus.com/inward/record.uri?eid=2-s2.0-85110971235&doi=10.13005%2fbpj%2f2172&partnerID=40&md5=d967f0ab42728fa05df28dd316a8f615	Faculty of Medicine, Universitas Pembangunan Nasional Veteran, Jakarta, 12450, Indonesia; Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Department of Chemistry, Universitas Lampung, Bandar Lampung, 35145, Indonesia	Susantiningsih, T., Faculty of Medicine, Universitas Pembangunan Nasional Veteran, Jakarta, 12450, Indonesia, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Makkiyah, F.A., Faculty of Medicine, Universitas Pembangunan Nasional Veteran, Jakarta, 12450, Indonesia; Thadeus, M.S., Faculty of Medicine, Universitas Pembangunan Nasional Veteran, Jakarta, 12450, Indonesia; Yulianti, R., Faculty of Medicine, Universitas Pembangunan Nasional Veteran, Jakarta, 12450, Indonesia; Hadi, S., Department of Chemistry, Universitas Lampung, Bandar Lampung, 35145, Indonesia	Obesity is linked to more deaths worldwide. In obesity, there will be a dysregulation of growth signals such as tumorigenesis. Despite the fact that obesity is tend to progress to acute liver damage, not many study using 2-nitropropane (2NP) as a hepatoxicity agent are undertaken especially in obese mice. This study aimed to determine the regime of 2NP that causes acute liver damage. This is an experimental research using a post-test control design group only, with 3 groups of mice ie O1 (obesity), O2+2-NP 1x (induced by 2NP 100 mg/kg BW once), and O2+2-NP 2x (induced by 2NP 100 mg/kg BW twice). At 10 weeks, rats were sacrificed and 100 mg liver tissue were collected for MDA, GSH, MnSOD and CAT enzymes analysis. Analysis statistics were performed by SPSS by one-way Anova and post hoc Tukey. MDA levels of mice were found to be increased in 2NP group than control (3.768 ± 0.407 nmol/ mg) (p < 0,01). Liver GSH, MnSOD and CAT levels of both single injection 2-NP and repeated injection 2-NP groups decreased compared to those of controls (p<0,01). Repeated injection of 2-NP worsen the acute liver damage in obese mice. © 2021 Oriental Scientific Publishing Company. All rights reserved.	2-NP; CAT; GSH; MDA; MnSOD; Obesity	2 nitropropane; catalase; glutathione peroxidase; ketamine; manganese superoxide dismutase; oxygen; reactive oxygen metabolite; superoxide dismutase; triacylglycerol; xylazine; analysis of variance; animal model; animal tissue; Article; body weight; carcinogenesis; centrifugation; controlled study; data analysis software; DNA damage; enzyme activity; liver injury; liver tissue; male; mouse; nonhuman; obesity; oxidative stress; post hoc analysis; protein content; repeated drug dose	Oriental Scientific Publishing Company	09746242		Article	Q4	191	19920	View
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19	Tantri A.R., Sukmono R.B., Atmadja L.S.	57188933853;57204643526;57422197300;	Comparison of recovery time with target controlled infusion of propofol with sevoflurane anesthesia using bispectral index monitoring in vitrectomy surgery	2021	Anaesthesia, Pain and Intensive Care	25	6	707	712		https://www.scopus.com/inward/record.uri?eid=2-s2.0-85123272271&doi=10.35975%2fapic.v25i6.1689&partnerID=40&md5=a8e07d9abeb4fd0d01a1bb03c52954f1	Department of Anesthesiology and Intensive Care, Faculty of Medicine, Universitas Indonesia, Cipto Mangunkusumo National General Hospital, Pangeran Diponegoro Street No. 71, Kenari, Senen, DKI Jakarta, Central Jakarta, 10430, Indonesia	Tantri, A.R., Department of Anesthesiology and Intensive Care, Faculty of Medicine, Universitas Indonesia, Cipto Mangunkusumo National General Hospital, Pangeran Diponegoro Street No. 71, Kenari, Senen, DKI Jakarta, Central Jakarta, 10430, Indonesia; Sukmono, R.B., Department of Anesthesiology and Intensive Care, Faculty of Medicine, Universitas Indonesia, Cipto Mangunkusumo National General Hospital, Pangeran Diponegoro Street No. 71, Kenari, Senen, DKI Jakarta, Central Jakarta, 10430, Indonesia; Atmadja, L.S., Department of Anesthesiology and Intensive Care, Faculty of Medicine, Universitas Indonesia, Cipto Mangunkusumo National General Hospital, Pangeran Diponegoro Street No. 71, Kenari, Senen, DKI Jakarta, Central Jakarta, 10430, Indonesia	Background: Rapid recovery after anesthesia is critical and is associated with the anesthetic agents used. The bispectral index (BIS) monitoring to guide anesthetic agents' doses may play a significant role in the recovery time. This study compared recovery time after Target Controlled Infusion (TCI) of propofol with sevoflurane anesthesia by using BIS monitoring during vitrectomy surgery. Methodology: This was a prospective observational, randomized study on 40 patients aged 18-65 y, physical status ASA I-II, body mass index (BMI) 18-30 kg/m2, who underwent vitrectomy surgery. Subjects were randomly assigned into two groups, Group P - the TCI propofol group, and Group S - the sevoflurane group. Subjects in the Group P received TCI propofol (Schnider), and subjects in the Group S received sevoflurane for anesthesia maintenance, with a targeted BIS score of 40-60. Inj. fentanyl 1 μg/kg was administered if there was an increase in blood pressure, heart rate and/or BIS that could not be overcome by increasing the dose of TCI propofol or sevoflurane. Recovery time was calculated from when the maintenance regimen was stopped until the patient was able to obey simple commands. Recovery time, fentanyl consumption, postoperative agitation, nausea and vomiting incidence were noted and analyzed with SPSS v21.0 for Windows. T-Test or Mann-Whitney U test was performed to analyze the data. Result: Recovery time in the Group P [11.5 (5-25) min)] was not significantly different from the Group S [9 (4-18) min, p = 0.139]. Total fentanyl consumption was higher in the Group P than in the Group S (1.765 vs. 1.428 μg/kg). The frequency of agitation during recovery was higher in the Group S than in the Group P (30% vs. 20%) Conclusion: There was no significant difference in recovery time between TCI propofol and sevoflurane anesthesia using BIS monitoring in vitrectomy. Total fentanyl consumption was higher in the propofol group than in the sevoflurane group. The impact of these anesthetic regimens on postoperative agitation needs further investigation. © 2021 Faculty of Anaesthesia, Pain and Intensive Care, AFMS. All rights reserved.	BIS; Bispectral index monitoring; Intravenous anesthesia; Propofol; Sevoflurane; Target Controlled Infusion; TCI; Vitrectomy		Faculty of Anaesthesia, Pain and Intensive Care, AFMS	16078322		Article	Q3	170	21404	View
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389	Bangun K., Sukasah C.L., Dilogo I.H., Indrani D.J., Siregar N.C., Pandelaki J., Iskandriati D., Kekalih A., Halim J.	36902624600;57218391534;56161962800;6602774472;6508087790;35759266900;6507742011;55633562200;57219398869;	Bone Growth Capacity of Human Umbilical Cord Mesenchymal Stem Cells and BMP-2 Seeded Into Hydroxyapatite/Chitosan/Gelatin Scaffold in Alveolar Cleft Defects: An Experimental Study in Goat	2021	Cleft Palate-Craniofacial Journal	58	6	707	717	1	https://www.scopus.com/inward/record.uri?eid=2-s2.0-85092575595&doi=10.1177%2f1055665620962360&partnerID=40&md5=a3280d360d1de28c8353dffc23d716b3	Department of Plastic and Reconstructive Surgery, Cleft and Craniofacial Center, Cipto Mangunkusumo General Hospital, Jakarta, Indonesia; Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Unit Pelayanan Terpadu Teknologi Kedokteran Sel Punca (Stem Cell Research Center), Cipto Mangunkusumo General Hospital, Jakarta, Indonesia; Department of Dental Material Science and Technology, Faculty of Dentistry, Universitas Indonesia, Jakarta, Indonesia; Anatomical Pathology Department, Cipto Mangunkusumo General Hospital, Jakarta, Indonesia; Radiology Department of Cipto, Mangunkusumo General Hospital, Jakarta, Indonesia; Primate Research Center of Bogor Agricultural Institute, Bogor, Indonesia; Community Medicine Department, Cipto Mangunkusumo General Hospital, Jakarta, Indonesia; Cipto Mangunkusumo General Hospital, Jakarta, Indonesia	Bangun, K., Department of Plastic and Reconstructive Surgery, Cleft and Craniofacial Center, Cipto Mangunkusumo General Hospital, Jakarta, Indonesia; Sukasah, C.L., Department of Plastic and Reconstructive Surgery, Cleft and Craniofacial Center, Cipto Mangunkusumo General Hospital, Jakarta, Indonesia, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Dilogo, I.H., Unit Pelayanan Terpadu Teknologi Kedokteran Sel Punca (Stem Cell Research Center), Cipto Mangunkusumo General Hospital, Jakarta, Indonesia; Indrani, D.J., Department of Dental Material Science and Technology, Faculty of Dentistry, Universitas Indonesia, Jakarta, Indonesia; Siregar, N.C., Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia, Anatomical Pathology Department, Cipto Mangunkusumo General Hospital, Jakarta, Indonesia; Pandelaki, J., Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia, Radiology Department of Cipto, Mangunkusumo General Hospital, Jakarta, Indonesia; Iskandriati, D., Primate Research Center of Bogor Agricultural Institute, Bogor, Indonesia; Kekalih, A., Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia, Community Medicine Department, Cipto Mangunkusumo General Hospital, Jakarta, Indonesia; Halim, J., Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia, Cipto Mangunkusumo General Hospital, Jakarta, Indonesia	Objective: To evaluate bone regeneration in alveolar defects treated with human umbilical cord–derived mesenchymal stem cells (hUCMSCs), hydroxyapatite/chitosan/gelatin (HA/CS/Gel) scaffold, and bone morphogenic protein-2 (BMP-2) in Capra hircus models. Design: Randomized posttest-only control group design. Setting: Animal Hospital at Bogor Agricultural Institute. Participants: Healthy and equally treated 24 female Capra hircus/goats. Intervention: Animals were randomly assigned to 3 experimental group design (iliac crest alveolar bone graft/ICABG [control], HA/Cs/Gel+BMP-2 [Novosys], and HA/Cs/Gel+BMP-2+UCMSCs). Graft materials were implanted in surgically made alveolar defects. Main Outcome Measures: Postoperative functional score and operating time were assessed. New bone growth, bone density, inflammatory cells recruitment, and neoangiogenesis were evaluated based on radiological and histological approach at 2 time points, week 4 and 12. Statistical analysis was done between treatment groups. Results: Operating time was 34% faster and functional score 94.5% more superior in HA/Cs/Gel+BMP-2+hUCMSC group. Bone growth capacity in HA/Cs/Gel+BMP-2+UCMSCs mimicked ICABG, but ICABG showed possibility of bone loss between week 4 and 12. The HA/Cs/Gel+BMP-2+UCMSCs showed early bone repopulation and unseen inflammatory cells and angiogenesis on week 12. Discussion and Conclusion: The HA/Cs/Gel+BMP-2+hUCMSCs were superior in enhancing new bone growth without donor site morbidity compared to ICABG. The presence of hUCMSCs in tissue-engineered alveolar bone graft (ABG), supported with paracrine activity of the resident stem cells, initiated earlier new bone repopulation, and completed faster bone regeneration. The HA/Cs/Gel scaffold seeded with UCMSCs+BMP-2 is a safe substitute of ICABG to close alveolar bone defects suitable for patients with cleft lip, alveolus, and palate. © American Cleft Palate-Craniofacial Association. All rights reserved 2020.	alveolar bone grafts; bone regeneration; hydroxyapatite/chitosan/gelatin scaffold; iliac crest bone graft; mesenchymal stem cells; tissue engineering	bone morphogenetic protein 2; chitosan; gelatin; hydroxyapatite; gelatin; hydroxyapatite; adult; alveolar bone; alveolar bone grafting; angiogenesis; animal experiment; animal model; animal tissue; Article; bone density; bone graft; bone growth; bone regeneration; controlled study; domestic goat; donor site; female; histology; human; human cell; iliac crest; inflammatory cell; jaw malformation; morbidity; nonhuman; operation duration; osteolysis; outcome assessment; paracrine signaling; umbilical cord mesenchymal stem cell; animal; bone development; goat; mesenchymal stem cell; tissue scaffold; umbilical cord; Animals; Bone Development; Bone Regeneration; Chitosan; Durapatite; Female; Gelatin; Goats; Humans; Mesenchymal Stem Cells; Tissue Scaffolds; Umbilical Cord	SAGE Publications Ltd	10556656	34047209	Article	Q2	641	7859	View
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162	Sylvawani M., Setyohadi B., Purnamasari D., Abdullah M., Kurniawan M.R.	57225078775;6504721711;36519537700;7103393434;57192808936;	Comparison of insulin-like growth factor-1 and sclerostin levels between premenopausal women with and without diabetes mellitus	2021	Journal of Taibah University Medical Sciences	16	5	719	723		https://www.scopus.com/inward/record.uri?eid=2-s2.0-85109109686&doi=10.1016%2fj.jtumed.2021.05.007&partnerID=40&md5=4f913f9e9865492b0cdd9860adfea935	Division of Rheumatology, Department of Internal Medicine, School of Medicine, Universitas Syiah Kuala, Banda Aceh, Indonesia; Division of Rheumatology, Department of Internal Medicine, Faculty of Medicine Universitas Indonesia, Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Division of Metabolism and Endocrinology, Department of Internal Medicine, Faculty of Medicine, Universitas Indonesia, Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Division of Gastroenterology, Department of Internal Medicine, Faculty of Medicine Universitas Indonesia, Cipto Mangunkusumo Hospital, Jakarta, Indonesia	Sylvawani, M., Division of Rheumatology, Department of Internal Medicine, School of Medicine, Universitas Syiah Kuala, Banda Aceh, Indonesia; Setyohadi, B., Division of Rheumatology, Department of Internal Medicine, Faculty of Medicine Universitas Indonesia, Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Purnamasari, D., Division of Metabolism and Endocrinology, Department of Internal Medicine, Faculty of Medicine, Universitas Indonesia, Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Abdullah, M., Division of Gastroenterology, Department of Internal Medicine, Faculty of Medicine Universitas Indonesia, Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Kurniawan, M.R., Division of Rheumatology, Department of Internal Medicine, School of Medicine, Universitas Syiah Kuala, Banda Aceh, Indonesia	Objectives: This study assesses the serum levels of insulin-like growth factor-1 (IGF-1) and sclerostin as markers of decreased bone formation in premenopausal women with type 2 diabetes mellitus. Methods: A cross-sectional study was conducted to measure serum levels of IGF-1 and sclerostin in 40 premenopausal women with and without diabetes mellitus using an enzyme-linked immunosorbent assay. The levels of IGF-1 and sclerostin were compared between the groups using the Mann Whitney test and unpaired t-test, respectively. Results: The median IGF-1 serum levels were 40.60 ng/mL and 42.7 ng/mL in the diabetic and non-diabetic groups, respectively, with no significant difference. The serum levels of sclerostin were significantly higher in the diabetic group than in the non-diabetic group (132.1 pg/mL and 96.0 pg/mL, respectively; p < 0.001). Conclusion: The levels of sclerostin were significantly higher in premenopausal women with diabetes mellitus than in the non-diabetic group. Since sclerostin influences the differentiation and maturation of osteoblasts, serum sclerostin might potentially be useful as a marker of decreased bone formation in premenopausal women with diabetes. © 2021 The Authors	Diabetes mellitus; IGF-1; Osteoblasts; Premenopause; Sclerostin	alanine aminotransferase; collagen type 1; creatinine; hemoglobin A1c; insulin; oral antidiabetic agent; sclerostin; somatomedin C; adult; aged; Article; body mass; bone metabolism; cell differentiation; cell maturation; civil servant; comparative study; controlled study; cross-sectional study; diabetic patient; enzyme linked immunosorbent assay; estimated glomerular filtration rate; female; housewife; human; major clinical study; non insulin dependent diabetes mellitus; obesity; ossification; osteoblast; premenopause; private sector; protein blood level	Elsevier B.V.	16583612		Article	Q3	269	15910	View
724(1)
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417	Yunir E., Soewondo P., Soelistijo S.A., Rudijanto A.	36520254800;23475336100;57211324846;23499422500;	Knowledge and behavior changes in clinician after training of partnership for Diabetes Control in Indonesia	2021	Diabetes and Metabolic Syndrome: Clinical Research and Reviews	15	3	719	724		https://www.scopus.com/inward/record.uri?eid=2-s2.0-85103636919&doi=10.1016%2fj.dsx.2021.03.012&partnerID=40&md5=69390ed0f1d97f773993433ca4e7d1d0	Division of Endocrinology and Metabolism, Department of Internal Medicine Dr. Cipto Mangunkusumo National Referral Hospital, Faculty of Medicine Universitas Indonesia, Jl. Diponegoro No.71, Central Jakarta, 10430, Indonesia; Surabaya Diabetes and Nutrition Centre, Department of Internal Medicine, Universitas Airlangga, Jl. Mayjen Prof. Dr. Moestopo No.47, Surabaya, 60132, Indonesia; Division of Endocrinology and Metabolism, Department of Internal Medicine, Universitas Brawijaya, Jl. Veteran Malang, Malang, 65145, Indonesia	Yunir, E., Division of Endocrinology and Metabolism, Department of Internal Medicine Dr. Cipto Mangunkusumo National Referral Hospital, Faculty of Medicine Universitas Indonesia, Jl. Diponegoro No.71, Central Jakarta, 10430, Indonesia; Soewondo, P., Division of Endocrinology and Metabolism, Department of Internal Medicine Dr. Cipto Mangunkusumo National Referral Hospital, Faculty of Medicine Universitas Indonesia, Jl. Diponegoro No.71, Central Jakarta, 10430, Indonesia; Soelistijo, S.A., Surabaya Diabetes and Nutrition Centre, Department of Internal Medicine, Universitas Airlangga, Jl. Mayjen Prof. Dr. Moestopo No.47, Surabaya, 60132, Indonesia; Rudijanto, A., Division of Endocrinology and Metabolism, Department of Internal Medicine, Universitas Brawijaya, Jl. Veteran Malang, Malang, 65145, Indonesia	Background and aims: One of the main determinants of successful diabetes management is the quality of healthcare provider including general practitioner and internist which can be increased through medical training. This study aimed to describe the changes of clinician's knowledge and behavior of comprehensive diabetes management training program around Indonesia. Method: We conducted a three-day training program for general practitioners and internists for 3.5 years, 2013 to 2016. All clinicians invited as voluntary participant to send their patient data from medical record. Each participant was expected to submit a minimum of 25 type 2 diabetes (T2DM) set patient data before and 6 months after training program to analyze the impact of program in physician knowledge and behavior related to diabetes management. Result: 120 of 489 voluntary participants submitted completed baseline data with 4676 patient data. Meanwhile, only 32 participants that submitted completed data of 6 months before after training with 886 patient data. Most of parameters were improve before and after program. The greatest and lowest improvement were on A1c measurement (21%) and smoking assessment (2%). Conclusion: Intensive seminar and training was not enough to empower diabetes management. This research might push the creation of clinical practice program that were tailored to each care facilities and integrated within routine care aimed at continual improvement of its healthcare worker. © 2021	Behavior; Diabetes; Knowledge; Training	fibric acid derivative; hemoglobin A1c; antidiabetic agent; biological marker; glycosylated hemoglobin; hemoglobin A1c protein, human; adult; aged; Article; behavior; behavior change; controlled study; diabetes control; diabetes mellitus; diabetic complication; female; general practitioner; health personnel attitude; human; Indonesia; internist; major clinical study; male; medical education; middle aged; non insulin dependent diabetes mellitus; patient coding; priority journal; retrospective study; smoking; young adult; attitude to health; blood; clinical competence; education; follow up; glucose blood level; health care personnel; internal medicine; medical education; non insulin dependent diabetes mellitus; procedures; professional practice; prognosis; psychology; Adult; Aged; Biomarkers	Elsevier Ltd	18714021	33813247	Article	Q2	684	7304	View
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882	Siregar A.S., Werdhani R.A., Ascobat P., Nafrialdi N., Syam A.F., Hidayat R., Wangge G.	57221874281;57189088848;55795863600;8521176100;8443384400;37067327300;36497482500;	Development of a module for the prevention of nonsteroidal anti-inflammatory drugs-associated gastrointestinal adverse reactions in the elderly at a primary health center	2021	International Journal of Risk and Safety in Medicine	32	1	61	73		https://www.scopus.com/inward/record.uri?eid=2-s2.0-85100509044&doi=10.3233%2fJRS-200008&partnerID=40&md5=54ae75564e4436f8e65f2444aa1a5e10	Doctoral Program in Medical Sciences, Faculty of Medicine, University of Indonesia, Jakarta, Indonesia; Department of Pharmacology, Faculty of Medicine, State Islamic University Syarif Hidayatullah Jakarta, Jakarta, Indonesia; Department of Community Medicine, Faculty of Medicine, University of Indonesia, Jakarta, Indonesia; Department of Pharmacology and Therapeutics, Faculty of Medicine, University of Indonesia, Jakarta, Indonesia; Department of Internal Medicine, Faculty of Medicine, University of Indonesia, Jakarta, Indonesia; South East Asian Ministers of Education Organization - Regional Center for Food and Nutrition, Pusat Kajian Gizi Regional University of Indonesia (PKGR UI), Jakarta, Indonesia	Siregar, A.S., Doctoral Program in Medical Sciences, Faculty of Medicine, University of Indonesia, Jakarta, Indonesia, Department of Pharmacology, Faculty of Medicine, State Islamic University Syarif Hidayatullah Jakarta, Jakarta, Indonesia; Werdhani, R.A., Department of Community Medicine, Faculty of Medicine, University of Indonesia, Jakarta, Indonesia; Ascobat, P., Department of Pharmacology and Therapeutics, Faculty of Medicine, University of Indonesia, Jakarta, Indonesia; Nafrialdi, N., Department of Pharmacology and Therapeutics, Faculty of Medicine, University of Indonesia, Jakarta, Indonesia; Syam, A.F., Department of Internal Medicine, Faculty of Medicine, University of Indonesia, Jakarta, Indonesia; Hidayat, R., Department of Internal Medicine, Faculty of Medicine, University of Indonesia, Jakarta, Indonesia; Wangge, G., South East Asian Ministers of Education Organization - Regional Center for Food and Nutrition, Pusat Kajian Gizi Regional University of Indonesia (PKGR UI), Jakarta, Indonesia	BACKGROUND: The prevention of nonsteroidal anti-inflammatory drugs (NSAIDs) adverse reactions should start from the primary health center (PHC), as the first gatekeeper in community health services. However, there is no specific module available for health care professionals (HCPs) in Indonesia for the prevention of adverse drug reactions (ADR) at PHCs. NSAID is commonly used for the elderly treated at PHC in Indonesia, even though the ADR risk is well-known. OBJECTIVE: We aimed to develop a module to be used in PHC for preventing NSAID-associated upper gastrointestinal (GI) ADRs in elderly patients treated for musculoskeletal diseases. METHODS: The module was developed based on inputs from focus group discussions (FGD) among government health officers, PHC representatives, clinical pharmacologists, internal medicine and community medicine clinicians, pharmacovigilance experts, and professional organizations. A pilot implementation was conducted to test its feasibility and its effect on the HCPs' knowledge. RESULTS: Capacity building of HCPs, development of intra-HCP cooperation, as well as standard operating procedure (SOP) for the prescription of NSAID constituted important components of the module. A pilot study of the module in two PHCs showed that it was applicable with some recommendations for improvement in duration, number of participants, room space, presentation, and use of credit points as compliments. The HCPs' knowledge was improved after following the module. CONCLUSIONS: Our study showed that the module is feasible in PHC in Indonesia and useful in improving knowledge of HPC. © 2021 - IOS Press. All rights reserved.	adverse drug reactions; elderly; health care professional; Indonesia; NSAIDs; primary health center	nonsteroid antiinflammatory agent; antiinflammatory agent; drug; nonsteroid antiinflammatory agent; accreditation; aged; Article; capacity building; clinician; community medicine; continuing education; controlled study; dentist; feedback system; female; gastrointestinal symptom; geriatric patient; government; health care personnel; health center; human; Indonesia; internal medicine; major clinical study; male; medical society; midwife; musculoskeletal disease; nurse; pharmacist; pharmacologist; pharmacovigilance; physician; pilot study; prescription; primary health care; professional knowledge; program feasibility; questionnaire; teamwork; workflow; adverse drug reaction; drug surveillance program; Aged; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Drug-Related Side E	IOS Press BV	09246479	32894252	Article	Q3	306	14617	View
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685	Lubis A.M.T., Reksoprodjo A.Y., Kuncoro M.W., Ifran N.N.	15122639800;57208385626;57214136871;56091403800;	Post-acl reconstruction graft failure in severe gout arthritis patient	2021	International Medical Case Reports Journal	14		725	730		https://www.scopus.com/inward/record.uri?eid=2-s2.0-85117588489&doi=10.2147%2fIMCRJ.S325642&partnerID=40&md5=7d6c96304b0f081df9890285db073149	Department of Orthopedic & Traumatology, Cipto Mangunkusumo Hospital, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia	Lubis, A.M.T., Department of Orthopedic & Traumatology, Cipto Mangunkusumo Hospital, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Reksoprodjo, A.Y., Department of Orthopedic & Traumatology, Cipto Mangunkusumo Hospital, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Kuncoro, M.W., Department of Orthopedic & Traumatology, Cipto Mangunkusumo Hospital, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Ifran, N.N., Department of Orthopedic & Traumatology, Cipto Mangunkusumo Hospital, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia	Introduction: Pain and instability following an anterior cruciate ligament (ACL) reconstruction remain a significant issue. Common causes include infection and inflammation, and mechanical issues such as graft failure. Case Presentation: A 36-year-old male with an ACL reconstruction six years prior was admitted due to pain and swelling. The ACL graft that had ruptured was found arthrosco-pically. Numerous gout crystals and tophus were observed inside. This finding is suggested as a cause of this kind of complication. Discussion: Biological failure is one of the causes of graft failure. Gout arthritis is associated with internal derangement of the joint structures, which is reported in advanced case. Conclusion: Severe gouty arthritis, even though rare, could be an etiology of graft failure following ACL reconstruction and cause significant morbidity. © 2021 Lubis et al.	ACL reconstruction; Gout; Graft failure; Tophus	urate; adult; anterior cruciate ligament reconstruction; arthroscopic debridement; Article; case report; clinical article; gout; graft failure; hamstring graft; human; human tissue; hyperuricemia; joint effusion; joint limitation; joint stiffness; joint swelling; knee arthroscopy; knee instability; knee pain; knee radiography; male; muscle graft	Dove Medical Press Ltd	1179142X		Article	Q4	198	19482	View
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642	Soetisna T.W., Namretta L., Tirta E.S., Catur M.M.S.P., Ronidipta B., Tjubandi A.	57214887740;57394531400;57221753958;57394432600;57394432700;57211055979;	The importance of differentiating types of myxoma: a case report	2021	Cor et Vasa	63	6	733	735		https://www.scopus.com/inward/record.uri?eid=2-s2.0-85122153861&doi=10.33678%2fCOR.2021.063&partnerID=40&md5=ece88060ac36e8ce762e466c1383e95a	Department of Cardiothoracic and Vascular Surgery, National Cardiovascular Centre Harapan Kita, Jakarta, Indonesia; Department of Surgery, Faculty of Medicine, Universitas Indonesia, Indonesia	Soetisna, T.W., Department of Cardiothoracic and Vascular Surgery, National Cardiovascular Centre Harapan Kita, Jakarta, Indonesia, Department of Surgery, Faculty of Medicine, Universitas Indonesia, Indonesia; Namretta, L., Department of Cardiothoracic and Vascular Surgery, National Cardiovascular Centre Harapan Kita, Jakarta, Indonesia; Tirta, E.S., Department of Cardiothoracic and Vascular Surgery, National Cardiovascular Centre Harapan Kita, Jakarta, Indonesia; Catur, M.M.S.P., Department of Cardiothoracic and Vascular Surgery, National Cardiovascular Centre Harapan Kita, Jakarta, Indonesia; Ronidipta, B., Department of Cardiothoracic and Vascular Surgery, National Cardiovascular Centre Harapan Kita, Jakarta, Indonesia; Tjubandi, A., Department of Cardiothoracic and Vascular Surgery, National Cardiovascular Centre Harapan Kita, Jakarta, Indonesia, Department of Surgery, Faculty of Medicine, Universitas Indonesia, Indonesia	Myxoma shows unspecific symptoms similar to other cardiac disorders. Late resection of myxoma will worsen output such as congestive heart failure, cardiac arrhythmia, and cardiac embolism, causing sudden death. Early diagnosis and surgical excision of cardiac myxomas, especially with the villous surface, must be done as soon as possible. Additional diagnostic examination was needed to define types of myxoma for earlier treatment to prevent complications. We present a case of atrial myxoma which was diagnosed and treated earlier than the median time reviewed by the previous study. This paper focuses on the importance of early diagnosis and defining types of myxoma. © 2021, ČKS.	Myxoma; Tumor; Villous surface	adult; cardiopulmonary bypass; case report; clinical article; color Doppler flowmetry; dyspnea; early diagnosis; heart atrium myxoma; heart atrium septum defect; human; human tissue; male; middle aged; mitral valve regurgitation; physical examination; Review; sinus bradycardia; sternotomy; transthoracic echocardiography	Czech Society of Cardiology Z.S	00108650		Review	Q4	177	20889	View
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716	Dewi S., Sadikin M., Mulyawan W.	57192904541;36981411100;57192910410;	Oxidative stress in the heart of rats exposed to acute intermittent hypobaric hypoxia	2021	Ukrainian Biochemical Journal	93	3	68	74		https://www.scopus.com/inward/record.uri?eid=2-s2.0-85114748388&doi=10.15407%2fubj93.03.068&partnerID=40&md5=a11d4d4d31ac5bf34a38f63a8507d433	Department of Biochemistry and Molecular Biology, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Department of Aerophysiology, Air Force Indonesian National Army, Lakespra Saryanto, Jakarta, Indonesia	Dewi, S., Department of Biochemistry and Molecular Biology, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Sadikin, M., Department of Biochemistry and Molecular Biology, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Mulyawan, W., Department of Aerophysiology, Air Force Indonesian National Army, Lakespra Saryanto, Jakarta, Indonesia	It is known that the altitude area causes hypoxic conditions due to the low oxygen partial pressure. This study was conducted to estimate oxidative stress indices in the heart tissue after Wister rats exposure to the acute intermittent hypobaric hypoxia. Hypobaric hypoxia exposure was simulated by keeping the rats in a hypobaric chamber for 1 min at 35,000 feet altitude. After that the altitude was gradually reduced to 30,000 and 25,000 feet and maitained for 5 min. 25 male Wistar rats were divided into control group and four treatment groups (I-IV), consisting of rats exposed 1, 2, 3 and 4 times to hypobaric hypoxia with a frequency once a week. The animals were removed from the experiment at the height of 18,000 feet and the heart tissue was obtained. The carbonyl groups and MDA levels and superoxide dismutase and catalase activity were exami-ned in the supernatant of the heart tissue homogenate. In the samples of group I, the decrease in catalase activity with a simultaneous notable increase in carbonyl groups level was observed compared to control. In the samples of groups III and IV, the carbonyl level normalized and the activity of both antioxidant enzymes increased significantly. It was concluded that the increase of antioxidant enzymes activity can contribute to cardiac tissue adaptive response to acute hypobaric hypoxia exposure. © 2021 Dewi S. et al.	Acute intermittent hypobaric hypoxia; Antioxidant enzymes; Heart; Oxidative stress		Palladin Institute of Biochemistry of the NASU	24094943		Article	Q4	173	21241	View

Publikasi Scopus 926 artikel (Per 14 Maret 2022)