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Riset dan Pengabdian Masyarakat Do Research Sosial Service and Innovation

Id	Authors	Author S Id	Title	Year	Source Title	Volume	Issue	Art No	Page Start	Page End	Cited By	Link	Affiliations	Authors With Affiliations	Abstract	Author Keywords	Index Keywords	Publisher	Issn	Pubmed Id	Document Type	Sjr Best Quartile	Sjr	Sjr Rank
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Gastroenterology; Hepatology; Infection; Internal medicine; Pulmonology; Tropical disease(1)
No records
828	Suryana K.D., Simadibrata M., Renaldi K.	57222750873;23499598400;57190963547;	Impact of COVID-19 on the Gut: A Review of the Manifestations, Pathology, Management, and Challenges	2021	Acta medica Indonesiana	53	1		96	104	4	https://www.scopus.com/inward/record.uri?eid=2-s2.0-85103994291&partnerID=40&md5=8f9253303dd7921abe223346263c353b	Department of Internal Medicine, Faculty of Medicine, Universitas Indonesia/ Dr. Cipto Mangunkusumo General Hospital National HospitalJakarta, Indonesia	Suryana, K.D., Department of Internal Medicine, Faculty of Medicine, Universitas Indonesia/ Dr. Cipto Mangunkusumo General Hospital National HospitalJakarta, Indonesia; Simadibrata, M.; Renaldi, K.	SARS-CoV-2 is a virus that can enter its hosts through the Angiotensin Converting Enzyme-2 (ACE2) receptor. ACE2 is mainly expressed in cells of the gastrointestinal tract, such as the esophageal epithelium and enterocytes from the ileum-colon. Coronavirus Disease 2019 (COVID-19) has varying clinical symptoms and presents differently in individuals, ranging from asymptomatic carriers to moderate clinical spectrum with mild pneumonia clinical features, and to a severe clinical presentation with dyspnea and hypoxia, leading to death due to respiratory or multi-organ failure. COVID-19 infection can also manifest themselves in the form of gastrointestinal symptoms such as diarrhea, vomiting, nausea, and abdominal pain. Severe complications of gastrointestinal COVID-19 infections include hemorrhage or perforation of the gastrointestinal tract and severe inflammation, which can adversely affect the intestinal immune system, and therefore the systemic immune system of the host. Furthermore, COVID-19 has also shown to affect microbiota homeostasis in the digestive tract. To date, no clear explanation is available regarding the pathophysiology of gastrointestinal SARS-CoV-2 infection, fecal RNA detection, and the possibility of fecal-oral transmission of SARS-CoV-2. This review aims to discuss the effects of SARS-CoV-2 infection on the digestive tract, microbiota, and lung, and the possibility of fecal-oral transmission in COVID-19.	Gastroenterology; Hepatology; Infection; Internal medicine; Pulmonology; Tropical disease	feces; gastrointestinal disease; gastrointestinal tract; human; immunology; isolation and purification; pathogenicity; pathophysiology; physiology; prevention and control; virology; COVID-19; Feces; Gastrointestinal Diseases; Gastrointestinal Tract; Humans; SARS-CoV-2	NLM (Medline)	01259326	33818412	Review	Q3	321	14162	View
Genitalia anomaly; Good outcome; Modified Passerini-Glazel feminizing genitoplasty(1)
No records
320	Priyatini T., Roziana	57192265423;57218684529;	Modified Passerini-Glazel feminizing genitoplasty outcomes in adults: Two rare cases	2021	International Journal of Surgery Case Reports	84		106086				https://www.scopus.com/inward/record.uri?eid=2-s2.0-85107634308&doi=10.1016%2fj.ijscr.2021.106086&partnerID=40&md5=1f174f5a5decf1024dcb84cf6d7d80f7	Urogynecology Division, Department of Obstetrics and Gynecology, Faculty of Medicine, University of Indonesia/Dr. Cipto Mangunkusumo Hospital, Jakarta, Indonesia	Priyatini, T., Urogynecology Division, Department of Obstetrics and Gynecology, Faculty of Medicine, University of Indonesia/Dr. Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Roziana, Urogynecology Division, Department of Obstetrics and Gynecology, Faculty of Medicine, University of Indonesia/Dr. Cipto Mangunkusumo Hospital, Jakarta, Indonesia	Introduction: Modified Passerini-Glazel feminizing genitoplasty is typically performed in children with atypical genitalia. In our article, we have performed the procedure in adults with genital anomalies. Case presentation: The first case was a 22 years old woman who was planning to get married. She presented with a chief complaint of having no vaginal canal. Gynecological examination showed no vaginal opening. The common channel was visible, and the size of the perineal body was 3 cm. The patient underwent vaginal reconstruction using a modified Passerini-Glazel technique without amnion graft. The second case was a 20 years old girl planning to get married, with a chief complaint of small vaginal introitus. Gynecology examination showed small minor labia with an introitus size of 1 cm. The patients underwent vaginal reconstruction and labioplasty using a modified Passerini-Glazel technique with an amnion graft. Both patients have undergone anal atresia surgery in childhood. Discussion: There was no difference in outcome between using amnion graft and without amnion graft following the modified Passerini-Glazel feminizing genitoplasty procedure. The first patient had been pregnant and had successful delivery by elective cesarean section. Moreover, the second patient had no complaint of sexual disorders after the procedure. No cases of dysuria, urinary tract infection, leukorrhea, hematocolpos, or malodorous vaginal discharge were reported in both cases. Conclusion: Modified Passerini-Glazel feminizing genitoplasty is a safe and effective procedure. Daily vaginal dilation in the postoperative period was unnecessary, and it allowed for an excellent cosmetic result. © 2021 The Authors	Genitalia anomaly; Good outcome; Modified Passerini-Glazel feminizing genitoplasty	polyglycolic acid; adult; amnion; anal mucosa; anus atresia; anus injury; anus surgery; bulbocavernosus muscle; case report; cesarean section; clinical article; clinical outcome; echography; female; follow up; gynecological examination; hematocolpos; high school graduate; human; hydrosalpinx; hysteroscopy; incision; labia minora; menstrual irregularity; menstruation; micturition; modified Passerini-Glazel feminizing genitoplasty; palpation; postoperative period; pregnancy; reconstructive surgery; scar; sexual dysfunction; sexual function; sexual intercourse; Short Survey; surgical technique; suture technique; tissue graft; unemployment; urine color; urogenital tract malformation; urologic surgery; uterus malformation; vagina; vagina aplasia; vagina mucosa; vaginoscopy; young adult	Elsevier Ltd	22102612		Short Survey	Q3	232	17549	View
gestation; immature intestines; rabbit; spermine; villi height(1)
No records
175	Tamba R.P., Moenadjat Y.	47761736600;57190371576;	Oral Spermine Supplementation in Gestated Rabbit: A Study on Villi Height of Immature Intestines	2021	Frontiers in Surgery	8		721560				https://www.scopus.com/inward/record.uri?eid=2-s2.0-85115713070&doi=10.3389%2ffsurg.2021.721560&partnerID=40&md5=ef2b810fab926ddb3b4313b8d20045f5	Faculty of Medicine, Department of Surgery Cipto, Mangunkusumo General Hospital, Universitas Indonesia, Jakarta, Indonesia	Tamba, R.P., Faculty of Medicine, Department of Surgery Cipto, Mangunkusumo General Hospital, Universitas Indonesia, Jakarta, Indonesia; Moenadjat, Y., Faculty of Medicine, Department of Surgery Cipto, Mangunkusumo General Hospital, Universitas Indonesia, Jakarta, Indonesia	Introduction: Immature intestines are the major problem in prematurity. Postnatal oral spermine has been shown in studies to improve intestinal maturation in rats and piglets. This study aimed to find out the efficacy of spermine in rabbits during gestation. Method: An experimental study was done in an unblinded, randomized manner on those treated with and without spermine administration. A morphological examination of hematoxylin–eosin-stained villi was performed under a light microscope with a focus on villi height. Data were subjected to analysis. Results: The median of the spermine-treated group was found to be higher at 24, 26, and 28 days than the non-spermine group, but was not significantly different. Conclusion: Oral spermine supplementation during gestation might improve intestinal villi height in immature rabbit intestines. © Copyright © 2021 Tamba and Moenadjat.	gestation; immature intestines; rabbit; spermine; villi height		Frontiers Media S.A.	2296875X		Article	Q2	483	10376	View
Giant Recurrence Pituitary Adenoma; Radiotherapy; Transphenoidal Removal Surgery(1)
No records
445	Pramono L.A., Yunir E., Tarigan T.J.E., Nusanti S., Aman R.A., Suroyo I.	37063602400;36520254800;36057746500;57189727162;57226434769;57204106272;	Giant Recurrence Pituitary Adenoma After Three Times Transphenoidal Removal Surgery, One Craniotomy Procedure, and 30 Doses of External Radiotherapy	2021	Acta medica Indonesiana	53	2		221	224		https://www.scopus.com/inward/record.uri?eid=2-s2.0-85111572434&partnerID=40&md5=3fbf4691ce27b57e71d3a91134445173	1. Department of Internal Medicine, Faculty of Medicine Universitas Indonesia - Cipto Mangunkusumo Hospital, Indonesia. 2. Department of Public Health and Nutrition, School of Medicine and Health Sciences Universitas Katolik Indonesia Atma Jaya - Department of Internal Medicine St Carolus HospitalJakarta, Indonesia	Pramono, L.A., 1. Department of Internal Medicine, Faculty of Medicine Universitas Indonesia - Cipto Mangunkusumo Hospital, Indonesia. 2. Department of Public Health and Nutrition, School of Medicine and Health Sciences Universitas Katolik Indonesia Atma Jaya - Department of Internal Medicine St Carolus HospitalJakarta, Indonesia; Yunir, E.; Tarigan, T.J.E.; Nusanti, S.; Aman, R.A.; Suroyo, I.	This is a case of 42nd year-old woman with history of sight loss in her both eyes. She experienced headache and visual field decrease gradually since 2014. After several laboratory and imaging examinations, from her dynamic pituitary magnetic resonance imaging (MRI), it is concluded that she had a giant adenoma of the pituitary gland which compressed to her optic chiasm. From her pituitary laboratory hormone panel, it is revealed that the tumor is a non-functioning pituitary adenoma. From the neuro-ophthalmology (campimetry) examinations, she had papillae atrophy in her both eyes and also bilateral temporal hemianopia.	Giant Recurrence Pituitary Adenoma; Radiotherapy; Transphenoidal Removal Surgery	adenoma; adult; case report; craniotomy; female; hemianopia; human; hypophysis tumor; nuclear magnetic resonance imaging; optic nerve; pathology; tumor recurrence; Adenoma; Adult; Craniotomy; Female; Hemianopsia; Humans; Magnetic Resonance Imaging; Neoplasm Recurrence, Local; Optic Nerve; Pituitary Neoplasms	NLM (Medline)	01259326	34251352	Article	Q3	321	14162	View
Glans cyst; Parameatal cyst; Urethral cyst(1)
No records
113	Tirtayasa P.M.W., Samuel A.G., Lisnawati, Retnowulan A.	56245176500;57226642220;24449072000;57226640316;	Parameatal glans cyst: A case report	2021	Urology Case Reports	39		101802				https://www.scopus.com/inward/record.uri?eid=2-s2.0-85112167978&doi=10.1016%2fj.eucr.2021.101802&partnerID=40&md5=a508fda307bc2bbe4ba2dcbc8048eb84	Department of Urology, Faculty of Medicine Universitas Udayana, Bali, Indonesia; Urology Consultant, Pelni General Hospital, Jakarta, Indonesia; Pathology Consultant, Pelni General Hospital, Jakarta, Indonesia; Department of Pathological Anatomy, Faculty of Medicine Universitas Indonesia, Jakarta, Indonesia	Tirtayasa, P.M.W., Department of Urology, Faculty of Medicine Universitas Udayana, Bali, Indonesia; Samuel, A.G., Urology Consultant, Pelni General Hospital, Jakarta, Indonesia; Lisnawati, Pathology Consultant, Pelni General Hospital, Jakarta, Indonesia, Department of Pathological Anatomy, Faculty of Medicine Universitas Indonesia, Jakarta, Indonesia; Retnowulan, A., Pathology Consultant, Pelni General Hospital, Jakarta, Indonesia, Department of Pathological Anatomy, Faculty of Medicine Universitas Indonesia, Jakarta, Indonesia	Parameatal glans cyst is unusual and only a few cases reported until currently. We presented a four-year-old boy with dysuria and inappropriate appearance of parameatal glans cyst. The cystic mass was slow-growing and was present since birth. Complete surgical excision was performed to prevent recurrencies and to achieve good cosmesis. © 2021 The Authors	Glans cyst; Parameatal cyst; Urethral cyst	Article; case report; child; clinical article; cuboidal epithelium; cyst; dysuria; epithelium; esthetic surgery; excision; follow up; general anesthesia; globular cystic swelling; histopathology; human; human tissue; male; parameatal glans cyst; penis glans; physical examination; preschool child; squamous epithelium; swelling; urethra; urethral meatus; urinalysis	Elsevier Inc.	22144420		Article	Q3	245	16962	View
Glioblastoma multiforme; Prognostic factors; Radiotherapy; Survival(1)
No records
2	Sudibio S., Anton J., Handoko H., Permata T.B.M., Kodrat H., Nuryadi E., Sofyan H.R., Mulyadi R., Aman R.A., Gondhowiardjo S.	57283461500;57328462500;57204105168;57197808751;57210639849;57197806814;57328366500;56403164500;36848942500;6508327402;	Outcome analysis and prognostic factors in patients of glioblastoma multiforme: An indonesian single institution experience	2021	Open Access Macedonian Journal of Medical Sciences	9			1410	1416		https://www.scopus.com/inward/record.uri?eid=2-s2.0-85119154241&doi=10.3889%2foamjms.2021.7502&partnerID=40&md5=9312ddc4112180679fb892c1d7cc2e79	Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Department of Radiation Oncology, Dr. Cipto Mangunkusumo National General Hospital, Jakarta, Indonesia; Department of Neurology, Dr. Cipto Mangunkusumo National General Hospital, Jakarta, Indonesia; Department of Radiology, Dr. Cipto Mangunkusumo National General Hospital, Jakarta, Indonesia; Department of Neurosurgery, Dr. Cipto Mangunkusumo National General Hospital, Jakarta, Indonesia	Sudibio, S., Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia, Department of Radiation Oncology, Dr. Cipto Mangunkusumo National General Hospital, Jakarta, Indonesia; Anton, J., Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia, Department of Radiation Oncology, Dr. Cipto Mangunkusumo National General Hospital, Jakarta, Indonesia; Handoko, H., Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia, Department of Radiation Oncology, Dr. Cipto Mangunkusumo National General Hospital, Jakarta, Indonesia; Permata, T.B.M., Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia, Department of Radiation Oncology, Dr. Cipto Mangunkusumo National General Hospital, Jakarta, Indonesia; Kodrat, H., Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia, Department of Radiation Oncology, Dr. Cipto Mangunkusumo National General Hospital, Jakarta, Indonesia; Nuryadi, E., Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia, Department of Radiation Oncology, Dr. Cipto Mangunkusumo National General Hospital, Jakarta, Indonesia; Sofyan, H.R., Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia, Department of Neurology, Dr. Cipto Mangunkusumo National General Hospital, Jakarta, Indonesia; Mulyadi, R., Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia, Department of Radiology, Dr. Cipto Mangunkusumo National General Hospital, Jakarta, Indonesia; Aman, R.A., Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia, Department of Neurosurgery, Dr. Cipto Mangunkusumo National General Hospital, Jakarta, Indonesia; Gondhowiardjo, S., Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia, Department of Radiation Oncology, Dr. Cipto Mangunkusumo National General Hospital, Jakarta, Indonesia	AIM: This study was done to assess the survival of patients with glioblastoma multiforme (GBM) and to identify factors that can affect patient survival. MATERIALS AND METHODS: From January 2015 to December 2019, 55 patients with histopathologically confirmed GBM and received adjuvant radiation/chemoradiation in our department were retrospectively analyzed. RESULTS: The median overall survival (OS) for entire cohort was 13 months and 1-year OS and 2-year OS rate were 52.7% and 3.6% with the mean follow-up period was 12 months. In univariate analysis, age (≤50 years vs. >50 years, p = 0.02), performance status (≥90 vs. 70–80 vs. <70, p < 0.001), radiation therapy oncology group recursive partitioning analysis (RTOG-RPA) classification (Class III vs. Class IV vs. Class V-VI, p < 0.001), parietal lobes tumor site (vs. others, p = 0.02), residual tumor volume (≤20.4 cm3 vs. >20.4 cm3, p = 0.001), and time to initiate adjuvant therapy (<4 weeks vs. 4-6 weeks vs. >6 weeks, p = 0.01) were significantly affect OS. In multivariate analysis, RTOG-RPA classification and involvement of parietal lobes were independent prognostic factors for OS. CONCLUSIONS: RTOG-RPA classification that consisted of age and performance status is an independent prognostic factor for the clinical outcome of GBM. Besides this well-known factor, we also identified the involvement of parietal lobe gives a strong negative influence on survival of GBM patients. © 2021 Sudibio Sudibio, Jellyca Anton, Handoko Handoko, Tiara Bunga Mayang Permata, Henry Kodrat, Endang Nuryadi, Henry Riyanto Sofyan, Rahmad Mulyadi, Renindra Ananda Aman, Soehartati Gondhowiardjo.	Glioblastoma multiforme; Prognostic factors; Radiotherapy; Survival	methylated DNA protein cysteine methyltransferase; adjuvant chemotherapy; adult; Article; basal ganglion; cancer prognosis; cancer radiotherapy; cancer size; cancer surgery; cancer survival; chemoradiotherapy; clinical outcome; cohort analysis; controlled study; corpus callosum; female; follow up; frontal lobe; glioblastoma; histopathology; human; human tissue; major clinical study; male; outcome assessment; overall survival; parietal lobe; prospective study; radiation dose; recursive partitioning; retrospective study; temporal lobe; tumor volume	Scientific Foundation SPIROSKI	18579655		Article	Q3	288	15252	View
Glutathione plus; Skin tone; Skin-lightening agent; Spot polarization; Spot ultraviolet(1)
No records
299	SITOHANG I.B.S., ANWAR A.I., JUSUF N.K., ARIMUKO A., NORAWATI L., VERONICA S.	56734569200;57205655192;57188840371;57222706279;57217009388;57217003979;	Evaluating oral glutathione plus ascorbic acid, alpha-lipoic acid, and zinc aspartate as a skin-lightening agent: An indonesian multicenter, randomized, controlled trial	2021	Journal of Clinical and Aesthetic Dermatology	14	7		E53	E58		https://www.scopus.com/inward/record.uri?eid=2-s2.0-85113537297&partnerID=40&md5=f7d6f0bdd3408b798182f7ccc399f039	Division of Cosmetic Dermatology, Department of Dermatology and Venereology, Faculty of Medicine, Universitas Indonesia Dr. Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Department of Dermatology and Venereology, Faculty of Medicine Universitas Hasanuddin Dr. Wahidin Sudirohusodo Hospital, Makassar, Indonesia; Division of Cosmetic Dermatology, Department of Dermatology and Venereology, Faculty of Medicine, Universitas Sumatera Utara-Universitas Sumatera Utara Hospital, Medan, Indonesia; Department of Dermatology and Venereology, Presidential-Army Central Hospital Gatot Soebroto, Jakarta, Indonesia	SITOHANG, I.B.S., Division of Cosmetic Dermatology, Department of Dermatology and Venereology, Faculty of Medicine, Universitas Indonesia Dr. Cipto Mangunkusumo Hospital, Jakarta, Indonesia; ANWAR, A.I., Department of Dermatology and Venereology, Faculty of Medicine Universitas Hasanuddin Dr. Wahidin Sudirohusodo Hospital, Makassar, Indonesia; JUSUF, N.K., Division of Cosmetic Dermatology, Department of Dermatology and Venereology, Faculty of Medicine, Universitas Sumatera Utara-Universitas Sumatera Utara Hospital, Medan, Indonesia; ARIMUKO, A., Department of Dermatology and Venereology, Presidential-Army Central Hospital Gatot Soebroto, Jakarta, Indonesia; NORAWATI, L., Department of Dermatology and Venereology, Presidential-Army Central Hospital Gatot Soebroto, Jakarta, Indonesia; VERONICA, S., Department of Dermatology and Venereology, Presidential-Army Central Hospital Gatot Soebroto, Jakarta, Indonesia	CLINICALTRIALS.GOV IDENTIFIER: NCT04105504. BACKGROUND: For Asians, especially women with darker skin tones (Fitzpatrick Skin Types IV and V), clear, bright skin is considered highly desirable, and various topical, oral, or injection-based cosmetic skin-lightening agents with different mechanisms of action are widely available across Asia. OBJECTIVE: We sought to investigate the effcacy and safety of an oral glutathione supplement comprising L-glutathione (fermentation), ascorbic acid, alpha-lipoic acid, and zinc (as zinc aspartate) as a skin-lightening agent. METHODS: This randomized, double-blind, controlled clinical trial was carried out at three teaching hospital-based dermatovenereology clinics in Indonesia. Participants were randomized to receive either the glutathione supplement or placebo capsules and were evaluated every four weeks over a 12-week study period. Total reduction in spot ultraviolet, spot polarization, and skin tone were measured and recorded using a Janus Facial Analysis System® (PIE Co., Ltd, Suwon-si, Gyeonggido, Korea). RESULTS: Eighty-three participants, aged between 33 and 50 years, completed the study. Reductions in spot ultraviolet in certain subgroups, spot polarization, and skin tone were greater in the glutathione supplement group than in the placebo group, but the difference was not statistically significant. Both the glutathione supplement and placebo groups experienced only mild side effects in the first four weeks. CONCLUSION: The oral glutathione supplement was slightly beneficial for skin lightening in particular subgroups, but the results were not statistically significant. Mild and temporary side effects were reported. Further research is required to more fully evaluate the effcacy of this glutathione supplement as a skin-lightening agent. © 2021 Matrix Medical Communications. All rights reserved.	Glutathione plus; Skin tone; Skin-lightening agent; Spot polarization; Spot ultraviolet	ascorbic acid; depigmenting agent; gelatin; glucose; glutathione; keratin; lynae mazthione; placebo; porphyrin; sunscreen; thioctic acid; zinc aspartate; acne; adult; Article; cheek; combination drug therapy; comedo; controlled clinical trial; controlled study; double blind procedure; drug capsule; drug efficacy; drug safety; epigastric pain; eye; female; follow up; forehead; human; Indonesia; major clinical study; melanogenesis; multicenter study; nausea; nose; outcome assessment; pigmentation; pruritus; randomized controlled trial; sebum; side effect; skin bump; skin disease; sun exposure; supplementation; teaching hospital; treatment duration; ultraviolet radiation; wrinkle	Matrix Medical Communications	19412789		Article	Q2	600	8425	View
government program; Indonesia; primary healthcare; PROLANIS; type 2 diabetes mellitus(1)
No records
893	Alkaff F.F., Illavi F., Salamah S., Setiyawati W., Ramadhani R., Purwantini E., Tahapary D.L.	57208781930;57221732812;57217109015;57221720254;57219870814;57221736394;55944492500;	The Impact of the Indonesian Chronic Disease Management Program (PROLANIS) on Metabolic Control and Renal Function of Type 2 Diabetes Mellitus Patients in Primary Care Setting	2021	Journal of Primary Care and Community Health	12					1	https://www.scopus.com/inward/record.uri?eid=2-s2.0-85099918670&doi=10.1177%2f2150132720984409&partnerID=40&md5=6ba221c547d10bfc27fa5120aa56a223	Department of Pharmacology and Therapy, Faculty of Medicine, Universitas Airlangga, Surabaya, East Java, Indonesia; Department of Internal Medicine, Dr.Cipto Mangunkusumo General Hospital, Faculty of Medicine Universitas Indonesia, Central Jakarta, Jakarta, Indonesia; Department of Public Health and Preventive Medicine, Faculty of Medicine, Universitas Airlangga, Surabaya, East Java, Indonesia; Faculty of Medicine, Universitas Airlangga, Surabaya, East Java, Indonesia; Politeknik Elektronika Negeri Surabaya, Surabaya, East Java, Indonesia; Metabolic, Cardiovascular, and Aging Cluster, The Indonesian Medical Education and Research Institute, Faculty of Medicine, Universitas Indonesia, Central Jakarta, Jakarta, Indonesia	Alkaff, F.F., Department of Pharmacology and Therapy, Faculty of Medicine, Universitas Airlangga, Surabaya, East Java, Indonesia; Illavi, F., Department of Internal Medicine, Dr.Cipto Mangunkusumo General Hospital, Faculty of Medicine Universitas Indonesia, Central Jakarta, Jakarta, Indonesia; Salamah, S., Department of Public Health and Preventive Medicine, Faculty of Medicine, Universitas Airlangga, Surabaya, East Java, Indonesia; Setiyawati, W., Faculty of Medicine, Universitas Airlangga, Surabaya, East Java, Indonesia; Ramadhani, R., Faculty of Medicine, Universitas Airlangga, Surabaya, East Java, Indonesia; Purwantini, E., Politeknik Elektronika Negeri Surabaya, Surabaya, East Java, Indonesia; Tahapary, D.L., Department of Internal Medicine, Dr.Cipto Mangunkusumo General Hospital, Faculty of Medicine Universitas Indonesia, Central Jakarta, Jakarta, Indonesia, Metabolic, Cardiovascular, and Aging Cluster, The Indonesian Medical Education and Research Institute, Faculty of Medicine, Universitas Indonesia, Central Jakarta, Jakarta, Indonesia	Background: Indonesia through its government National Health Insurance System has launched a non-communicable and chronic disease management program named Indonesian Chronic Disease Management Program (PROLANIS), with Type 2 Diabetes Mellitus (T2DM) and hypertension as the main focus. However, study that evaluates the clinical impact of PROLANIS in patients with T2DM is still scarce to this date. This study aims to evaluate the metabolic control and renal function of PROLANIS participants with T2DM every six month within the first 18-months of implementation. Methods: This study was a retrospective cohort study conducted at Wates sub-district, East Java using secondary data from PROLANIS group report from April 2018 to October 2019. The study population was T2DM patients who voluntarily joined the PROLANIS group in April 2018. The six-month-evaluation included metabolic parameters [body mass index (BMI), blood pressure, hemoglobin A1C, total cholesterol, high-density lipid, low-density lipid, and triglyceride (TG)] and renal parameters [blood urea nitrogen (BUN), creatinine serum, and urinary microalbumin]. Paired t-test and wilcoxon signed-rank test was used for the analysis, and the P-value was adjusted using Bonferroni correction. A P-value <.0015 was considered statistically significant, while a P-value between.0015 and.003 was considered as marginally significant. Results: A total of 30 participants were included in the analysis. Following the PROLANIS implementation, the only parameter of metabolic control that showed significant improvement was TG serum level (P <.001). Despite the worsening status of other metabolic parameters, the changes were not statistically significant except for BMI that was marginally significant (P =.002). From renal function, only BUN serum level was significantly deteriorated (P <.001), while the others did not significantly change. Conclusion: PROLANIS implementation in our study population seems to be ineffective. Future study with more primary healthcare centers needs to be done to scrutinize the clinical impact of this program nationwide. © The Author(s) 2021.	government program; Indonesia; primary healthcare; PROLANIS; type 2 diabetes mellitus	glycosylated hemoglobin; disease management; human; Indonesia; non insulin dependent diabetes mellitus; primary health care; retrospective study; Diabetes Mellitus, Type 2; Disease Management; Glycated Hemoglobin A; Humans; Indonesia; Primary Health Care; Retrospective Studies	SAGE Publications Inc.	21501319	33472499	Article	Q2	550	9179	View
Granulosa cell tumor; Menopause; Ovarium tumor; Pathology; Rare case(1)
No records
104	Rustamadji P., Wiyarta E., Anggraeni T.D., Siregar T.P.	55321572200;57221521342;57192894826;57222017915;	Adult granulosa cell tumor with minor foci of juvenile granulosa cell tumor in postmenopausal woman: A rare case report	2021	International Journal of Surgery Case Reports	88		106531				https://www.scopus.com/inward/record.uri?eid=2-s2.0-85117387663&doi=10.1016%2fj.ijscr.2021.106531&partnerID=40&md5=b928e465d23286856e05bfdba88bbaad	Department of Pathological Anatomy, Dr. Cipto Mangunkusumo National General Hospital, Central Jakarta, Jakarta 10430, Indonesia; Faculty of Medicine, Universitas Indonesia, Central Jakarta, Jakarta 10430, Indonesia; Department of Obstetrics and Gynecology, Dr. Cipto Mangunkusumo National General Hospital, Central Jakarta, Jakarta 10430, Indonesia; Department of Radiology, Dr. Cipto Mangunkusumo National General Hospital, Central Jakarta, Jakarta 10430, Indonesia	Rustamadji, P., Department of Pathological Anatomy, Dr. Cipto Mangunkusumo National General Hospital, Central Jakarta, Jakarta 10430, Indonesia; Wiyarta, E., Faculty of Medicine, Universitas Indonesia, Central Jakarta, Jakarta 10430, Indonesia; Anggraeni, T.D., Department of Obstetrics and Gynecology, Dr. Cipto Mangunkusumo National General Hospital, Central Jakarta, Jakarta 10430, Indonesia; Siregar, T.P., Department of Radiology, Dr. Cipto Mangunkusumo National General Hospital, Central Jakarta, Jakarta 10430, Indonesia	Introduction: Granulosa cell tumor (GCT) is a rare neoplasm that is divided into adult GCT (AGCT) and juvenile GCT (JGCT). Generally, a patient will only have the AGCT or JGCT subtypes. Here, we presented the first case of AGTC accompanied by focal JGTC in a postmenopausal woman. Presentation of case: A 63-year-old postmenopausal woman came with distended abdomen accompanied by postmenopausal bleeding. CT scan shows a solid mass with cystic degeneration. Laparotomy found a solid mass from the right ovary measuring 18 × 15 × 14 cm. The pathological results showed a diffuse tumor representing AGCT, accompanied by Call-Exner bodies and nuclear groove. In addition, minor foci were also found, which consist of well-defined margins tumor and follicular-like structures that resemble JGCT. The patient underwent bilateral salpingo-oophorectomy with a total hysterectomy and no recurrence in three months follow-up. Discussion: Age and clinical symptoms cannot be used as specific differentiators between AGTC and JGTC. Radiological imaging also shows a similar appearance of solid masses tumors with hemorrhagic or fibrotic changes, multilocular cystic lesions, or completely cystic tumors. The concomitant findings of JGCT and AGCT could be distinguished very carefully by anatomical pathology examination. It is crucial to differentiate AGCT from JGCT, especially to see the prognosis. Conclusion: The role of pathologists is needed in differentiating AGCT and JGCT, primarily when found simultaneously. © 2021	Granulosa cell tumor; Menopause; Ovarium tumor; Pathology; Rare case	abdominal distension; abdominal radiography; adult; adult disease; Article; ascites; bilateral salpingo-oophorectomy; cancer tissue; case report; cell proliferation; clinical article; contrast enhancement; defecation; drug use; echography; female; follow up; frozen section; granulosa cell; granulosa cell tumor; human; hysterectomy; hysteroscopy; inflammatory cell; International Federation of Gynecology and Obstetrics; juvenile granulosa cell tumor; laboratory test; laparotomy; micturition; middle aged; mitosis; mobilization; myometrium; physical examination; postmenopause; postmenopause bleeding; treatment planning; tumor volume; x-ray computed tomography	Elsevier Ltd	22102612		Article	Q3	232	17549	View
GRE MR imaging; Hemophilic arthropathy; Hemosiderin deposition; US(1)
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62	Prasetyo M., Mongan A.E., Chozie N.A., Prihartono J., Setiawan S.I.	57192905252;57226385960;57194329830;6602605635;57195939543;	Hemosiderin deposition evaluation in hemophilic ankle joints: association between US finding and gradient-recalled echo MR imaging sequence	2021	Insights into Imaging	12	1	107				https://www.scopus.com/inward/record.uri?eid=2-s2.0-85111352122&doi=10.1186%2fs13244-021-01050-1&partnerID=40&md5=7acc2e0c4841079a7e9e49379be1ff9e	Department of Radiology, Faculty of Medicine, Universitas Indonesia – Dr. Cipto Mangunkusumo National Central General Hospital, Jl. Diponegoro No.71, Jakarta Pusat, DKI Jakarta 10430, Indonesia; Department of Pediatric, Faculty of Medicine, Universitas Indonesia – Dr. Cipto Mangunkusumo National Central General Hospital, Jakarta, Indonesia; Departement of Community Medicine, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia	Prasetyo, M., Department of Radiology, Faculty of Medicine, Universitas Indonesia – Dr. Cipto Mangunkusumo National Central General Hospital, Jl. Diponegoro No.71, Jakarta Pusat, DKI Jakarta 10430, Indonesia; Mongan, A.E., Department of Radiology, Faculty of Medicine, Universitas Indonesia – Dr. Cipto Mangunkusumo National Central General Hospital, Jl. Diponegoro No.71, Jakarta Pusat, DKI Jakarta 10430, Indonesia; Chozie, N.A., Department of Pediatric, Faculty of Medicine, Universitas Indonesia – Dr. Cipto Mangunkusumo National Central General Hospital, Jakarta, Indonesia; Prihartono, J., Departement of Community Medicine, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Setiawan, S.I., Department of Radiology, Faculty of Medicine, Universitas Indonesia – Dr. Cipto Mangunkusumo National Central General Hospital, Jl. Diponegoro No.71, Jakarta Pusat, DKI Jakarta 10430, Indonesia	Background: Repeated bleeding in hemophilic arthropathy (HA) may result in severe degenerative changes and joint destruction. The gradient-recalled echo (GRE) sequence MR is proved to be the best method to detect hemosiderin deposition. However, MR is not widely available in developing countries, including Indonesia. Some studies have proposed ultrasonography (US) as an alternative tool in evaluating hemophilic joint. However, there is still some disagreement on the ability of US to detect hemosiderin deposition. Objective: To evaluate the association between US and GRE-sequence MR imaging in detecting hemosiderin deposition in hemophilic ankle joint. Material and methods: A total of 102 sites from 17 ankle joints of 11 boys with severe hemophilia A underwent US examination using a high-frequency linear array transducer. GRE-sequence MR examination was performed in sagittal view consistent with the sites scanned by US. Both examinations were performed on the same day, but MR interpretation was performed blindly at different times. The association between US and GRE-sequences in detecting hemosiderin deposition was analyzed using McNemar’s test. Results: Statistical analysis showed a significant association (p value < 0.001) between US and GRE MR in detecting hemosiderin deposition, but the association is weak (R = 0.26). Sensitivity and specificity of US for detecting hemosiderin deposition were 46.84% (95%CI: 35.51–58.40) and 95.65% (95%CI: 78.05–99.89), respectively, with positive predictive value 97.37% (95%CI: 84.29–99.61), negative predictive value 34.38% (95%CI: 29.50–39.60) and accuracy 57.84% (95%CI: 47.66–67.56). Conclusion: There was a weak association between US and GRE-sequences in detecting hemosiderin deposition of hemophilic ankle joint. © 2021, The Author(s).	GRE MR imaging; Hemophilic arthropathy; Hemosiderin deposition; US	gadolinium; hemosiderin; accuracy; adolescent; anisotropy; Article; child; clinical article; cross-sectional study; echography; gradient recalled echo; gray matter; hemophilic arthropathy; histopathology; human; image analysis; male; medial malleolus; nuclear magnetic resonance imaging; predictive value; sensitivity and specificity; synovectomy	Springer Science and Business Media Deutschland GmbH	18694101		Article	Q1	1405	2531	View

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