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871 |
Turana Y., Widyantoro B., Situmorang T.D., Delliana J., Roesli R.M.A., Danny S.S., Suhardjono, Sofiatin Y., Hermiawaty E., Kuncoro A.S., Barack R., Beaney T., Ster A.C., Poulter N.R., Santoso A. |
56083326000;35286148600;57202120316;57208720930;26428909500;56221848700;57205723084;56815068100;57208721982;56008103000;57202111674;55614780900;57221978746;7006154423;36905206100; |
May measurement Month 2018: An analysis of blood pressure screening results from Indonesia |
2021 |
European Heart Journal, Supplement |
22 |
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H66 |
H69 |
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2 |
https://www.scopus.com/inward/record.uri?eid=2-s2.0-85101322980&doi=10.1093%2fEURHEARTJ%2fSUAA031&partnerID=40&md5=16a05b90991c40fdd180dd4e051eaaad |
Department of Neurology, School of Medicine and Health Science, Atma Jaya Catholic University of Indonesia, Jakarta, 14440, Indonesia; Department of Cardiology - Vascular Medicine, Faculty of Medicine, Universitas Indonesia, National Cardiovascular Center, Harapan Kita Hospital, Jl. S. Parman Kav 87, Slipi, Jakarta, 11420, Indonesia; Division of Nephrology, Department of Internal Medicine, PGI Cikini Hospital, Jakarta, 10330, Indonesia; Department of Cardiology, Directorate of Non-Communicable Disease, Ministry of Health - Republic of Indonesia, Jalan Percetakan Negara 29, Jakarta, 10560, Indonesia; Department of Internal Medicine, Faculty of Medicine, Padjadjaran University, Hasan Sadikin General Hospital, Bandung, 40161, Indonesia; Division of Nephrology and Hypertension, Department of Internal Medicine, Faculty of Medicine, Universitas Indonesia-Cipto, Mangunkusumo National General Hospital, Jalan Pangeran Diponegoro No: 71, Jakarta, 10430, Indonesia; Department of Public Health, Faculty of Medicine, Padjadjaran University, Jalan Prof. Eijkman 38, Bandung, 40161, Indonesia; Department of Neurology, National Cardiovascular Center, Harapan Kita Hospital, Jl. S. Parman Kav 87, Slipi, Jakarta, 11420, Indonesia; Department of Cardiology, MMC Hospital, Jakarta, Indonesia; Imperial Clinical Trials Unit, Imperial College London, Stadium House, 68 Wood Lane, Shepherd's Bush, London, W12 7RH, United Kingdom; Department of Primary Care and Public Health, Imperial College London, St Dunstan's Road, London, W6 8RP, United Kingdom |
Turana, Y., Department of Neurology, School of Medicine and Health Science, Atma Jaya Catholic University of Indonesia, Jakarta, 14440, Indonesia; Widyantoro, B., Department of Cardiology - Vascular Medicine, Faculty of Medicine, Universitas Indonesia, National Cardiovascular Center, Harapan Kita Hospital, Jl. S. Parman Kav 87, Slipi, Jakarta, 11420, Indonesia; Situmorang, T.D., Division of Nephrology, Department of Internal Medicine, PGI Cikini Hospital, Jakarta, 10330, Indonesia; Delliana, J., Department of Cardiology, Directorate of Non-Communicable Disease, Ministry of Health - Republic of Indonesia, Jalan Percetakan Negara 29, Jakarta, 10560, Indonesia; Roesli, R.M.A., Department of Internal Medicine, Faculty of Medicine, Padjadjaran University, Hasan Sadikin General Hospital, Bandung, 40161, Indonesia; Danny, S.S., Department of Cardiology - Vascular Medicine, Faculty of Medicine, Universitas Indonesia, National Cardiovascular Center, Harapan Kita Hospital, Jl. S. Parman Kav 87, Slipi, Jakarta, 11420, Indonesia; Suhardjono, Division of Nephrology and Hypertension, Department of Internal Medicine, Faculty of Medicine, Universitas Indonesia-Cipto, Mangunkusumo National General Hospital, Jalan Pangeran Diponegoro No: 71, Jakarta, 10430, Indonesia; Sofiatin, Y., Department of Public Health, Faculty of Medicine, Padjadjaran University, Jalan Prof. Eijkman 38, Bandung, 40161, Indonesia; Hermiawaty, E., Department of Neurology, National Cardiovascular Center, Harapan Kita Hospital, Jl. S. Parman Kav 87, Slipi, Jakarta, 11420, Indonesia; Kuncoro, A.S., Department of Cardiology - Vascular Medicine, Faculty of Medicine, Universitas Indonesia, National Cardiovascular Center, Harapan Kita Hospital, Jl. S. Parman Kav 87, Slipi, Jakarta, 11420, Indonesia; Barack, R., Department of Cardiology, MMC Hospital, Jakarta, Indonesia; Beaney, T., Imperial Clinical Trials Unit, Imperial College London, Stadium House, 68 Wood Lane, Shepherd's Bush, London, W12 7RH, United Kingdom, Department of Primary Care and Public Health, Imperial College London, St Dunstan's Road, London, W6 8RP, United Kingdom; Ster, A.C., Imperial Clinical Trials Unit, Imperial College London, Stadium House, 68 Wood Lane, Shepherd's Bush, London, W12 7RH, United Kingdom; Poulter, N.R., Imperial Clinical Trials Unit, Imperial College London, Stadium House, 68 Wood Lane, Shepherd's Bush, London, W12 7RH, United Kingdom; Santoso, A., Department of Cardiology - Vascular Medicine, Faculty of Medicine, Universitas Indonesia, National Cardiovascular Center, Harapan Kita Hospital, Jl. S. Parman Kav 87, Slipi, Jakarta, 11420, Indonesia |
Elevated blood pressure (BP) is a significant burden worldwide, leading to high cardiocerebro-reno-vascular morbidity and mortality. For the second year of the May Measurement Month (MMM) campaign in Indonesia in 2018, we recruited 174 sites in 31 out of 34 provinces in Indonesia and screened through convenience sampling in public areas and rural primary health centres. Hypertension was defined as systolic BP ≥140 mmHg or diastolic BP ≥90 mmHg, or both, or on the basis of receiving antihypertensive medication. Blood pressure was measured three times followed the standard global MMM protocol, multiple imputation was used to estimate the mean of the 2nd and 3rd BP readings if these were not recorded. A total of 91 222 individuals were screened, and after multiple imputations, 27 331 (30.0%) had hypertension. Of individuals not receiving antihypertensive medication, 14 367 (18.4%) were hypertensive. Among the 47.4% of hypertensive individuals on antihypertensive medication, 10 106 (78.0%) had uncontrolled BP. MMM17 and MMM18 were still the most extensive standardized screening campaigns for BP measurement in Indonesia. Compared to the previous study, the proportion with uncontrolled BP on medication was significantly higher and provided the substantial challenges in managing hypertension in the rural community. © The Author(s) 2020. |
Blood pressure; Community; Control; Hypertension; Screening |
antihypertensive agent; adult; antihypertensive therapy; Article; blood pressure measurement; controlled study; cross-sectional study; female; human; hypertension; hypertensive patient; Indonesia; major clinical study; male; primary health care; priority journal; rural population |
Oxford University Press |
1520765X |
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Article |
Q3 |
389 |
12388 |
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872 |
Irawati Y., Priscilia F., Zakiyah H. |
57201260313;57222057383;57222068709; |
Orbital compressed air and diesel explosion injury resembling orbital cellulitis: An unusual case |
2021 |
American Journal of Case Reports |
22 |
1 |
e929671 |
1 |
5 |
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1 |
https://www.scopus.com/inward/record.uri?eid=2-s2.0-85101275391&doi=10.12659%2fAJCR.929671&partnerID=40&md5=80fd24f7f41fb31a24ce6feb9c9c1db4 |
Division of Plastic and Reconstructive Surgery, Department of Ophthalmology, Faculty of Medicine, Universitas Indonesia, Dr. Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Department of Ophthalmology, Dr. Cipto Mangunkusumo Hospital, Jakarta, Indonesia |
Irawati, Y., Division of Plastic and Reconstructive Surgery, Department of Ophthalmology, Faculty of Medicine, Universitas Indonesia, Dr. Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Priscilia, F., Department of Ophthalmology, Dr. Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Zakiyah, H., Department of Ophthalmology, Dr. Cipto Mangunkusumo Hospital, Jakarta, Indonesia |
Objective: Background: Case Report: Conclusions: Unusual clinical course In this observational case report, we describe a case of orbital cellulitis caused by blunt trauma from an orbital compressed air and diesel explosion injury. A 44-year-old man presented to our emergency department with a marked clinical worsening of right upper eyelid swelling, accompanied by pain, fever, and redness. Four days prior, the patient’s right eye was struck by a pressurized diesel engine explosion. He sought treatment at another hospital, where an initial examination was conducted and a small laceration was found and immediately treated with irrigation and medication. The wound became progressively worse, and on examination at our hospital, we diagnosed orbital cellulitis, multiple abscesses, and pneumo-orbital formations. There was no indication of infection from the ears, nose, throat, and oral cavity, which usually causes orbital cellulitis. Drainage, debridement, incision, and necrotomy with orbital decompression (canthotomy and cantholysis procedure) was then performed on the patient. Diesel explosion injury can cause orbital cellulitis which can appear to be a simple case at first but has a poor prognosis. Therefore, evaluating the patient’s trauma history, computed tomography scan, and histopathological examination are essential in establishing the diagnosis. As early as possible, a diagnosis should be made to prevent tissue damage due to inflammation. Surgical debridement and the administration of a corticosteroid and antibiotic were key to managing the presented case. © Am J Case Rep, 2021. |
Compressed Air; Explosions; Orbital Diseases |
amoxicillin plus clavulanic acid; artificial tear; C reactive protein; chloramphenicol; diclofenac; diesel fuel; eye drops; levofloxacin; methylprednisolone; metronidazole; omeprazole; potassium hydroxide; prednisolone acetate; sodium chloride; sultamicillin; thymol; abscess; adult; antibiotic sensitivity; Article; bacterium culture; blast injury; cantholysis; canthotomy; case report; chemosis; clinical article; clinical feature; compressed air; computer assisted tomography; conjunctival hemorrhage; conjunctival hyperemia; debridement; decompression surgery; diesel engine; disease exacerbation; disease severity; emergency ward; exophthalmos; eye edema; eye examination; eye lavage; eye pain; eye redness; eye surgery; eye swelling; eyelid disease; fever; follow up; Gram positive bacterium; h |
International Scientific Information, Inc. |
19415923 |
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33611333 |
Article |
Q3 |
247 |
16822 |
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873 |
Rosdiana D.S., Setiabudy R., Andalusia R., Gatot D., Louisa M., Bardosono S., Instiaty I. |
56955579800;6602316235;57191278723;6508292159;41461551400;21933841000;55703138400; |
Tpmt genetic variability and its association with hematotoxicity in indonesian children with acute lymphoblastic leukemia in maintenance therapy |
2021 |
Pharmacogenomics and Personalized Medicine |
14 |
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199 |
210 |
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2 |
https://www.scopus.com/inward/record.uri?eid=2-s2.0-85101168492&doi=10.2147%2fPGPM.S288988&partnerID=40&md5=45069dfc59e995d12723c15428e48bcd |
Department of Pharmacology and Therapeutics, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Dharmais National Cancer Hospital, Jakarta, Indonesia; Drug Registration Directorate, National Agency for Drug and Food Control, Jakarta, Indonesia; Division of Hematology-Oncology, Department of Pediatrics, Faculty of Medicine, Universitas Indonesia/Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Department of Nutrition, Faculty of Medicine, University of Indonesia, Jakarta, Indonesia |
Rosdiana, D.S., Department of Pharmacology and Therapeutics, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Setiabudy, R., Department of Pharmacology and Therapeutics, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Andalusia, R., Dharmais National Cancer Hospital, Jakarta, Indonesia, Drug Registration Directorate, National Agency for Drug and Food Control, Jakarta, Indonesia; Gatot, D., Division of Hematology-Oncology, Department of Pediatrics, Faculty of Medicine, Universitas Indonesia/Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Louisa, M., Department of Pharmacology and Therapeutics, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Bardosono, S., Department of Nutrition, Faculty of Medicine, University of Indonesia, Jakarta, Indonesia; Instiaty, I., Department of Pharmacology and Therapeutics, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia |
Purpose: Hematotoxicity monitoring in children with acute lymphoblastic leukemia (ALL) is critical to preventing life-threatening infections and drug discontinuation. The primary drug that causes hematotoxicity in ALL children is 6-mercaptopurine (6-MP). Genetic variability of the drug-metabolizing enzymes of 6-MP, thiopurine S-methyltransferase (TPMT), is one factor that might increase the susceptibility of children to hematotoxicity. The present study aimed to determine the variability in TPMT genotypes and phenotypes and its association with the occurrence of hematotoxicity in ALL children in maintenance therapy. Patients and Methods: A cross-sectional study was conducted at Cipto Mangunkusumo and Dharmais National Cancer Hospital, Jakarta, Indonesia, from June 2017 to October 2018. We included ALL patients, 1–18 years, who were receiving at least one month of 6-MP during maintenance therapy according to the Indonesian protocol for ALL 2013. Direct sequencing was used to determine TPMT*3A, *3B, and *3C genotypes, and LCMS/MS analysis was performed to measure the plasma concentrations of 6-MP and its metabolites. Association analysis between the TPMT genotype and hematotoxicity was evaluated using the unpaired t-test or Mann–Whitney’s test. Results: The prevalence of neutropenia, anemia, and thrombocytopenia in ALL children during maintenance therapy was 51.9%, 44.3%, and 6.6%, respectively. We found a low frequency of TPMT*3C, which is 0.95%. No association was found between hematotoxicity and TPMT genotypes or age, nutritional status, serum albumin levels, risk stratification, the daily dose of 6-MP, and cotrimoxazole co-administration. However, hematotoxicity was associated with 6-methylmercaptopurine (6-MeMP) plasma concentrations and the ratio 6-MeMP/6-thioguanine (6-TGN). We also found no association between TPMT genotypes and TPMT phenotypes. Conclusion: The 6-MeMP/6-TGN ratio is associated with hematotoxicity in ALL children during maintenance therapy but is not strong enough to predict hematotoxicity. © 2021 Rosdiana et al. |
Mercaptopurine; Methylmercaptopurine; Neutropenia; Thioguanine; Thiopurine methyltransferase |
6 methylthioinosine; albumin; cotrimoxazole; dexamethasone; methotrexate; thiopurine methyltransferase; tioguanine; vincristine; acute lymphoblastic leukemia; adolescent; adult; albumin blood level; anemia; Article; blood toxicity; child; cross-sectional study; drug blood level; drug safety; female; gene sequence; genetic variability; groups by age; human; human cell; Indonesia; Indonesian; liquid chromatography-mass spectrometry; maintenance therapy; major clinical study; male; neutropenia; nutritional status; prevalence; risk factor; thrombocytopenia; TPMT gene |
Dove Medical Press Ltd |
11787066 |
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Article |
Q2 |
845 |
5609 |
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874 |
Gondhowiardjo S., Christina N., Ganapati N.P.D., Hawariy S., Radityamurti F., Jayalie V.F., Octavianus S., Putra A.P., Sekarutami S.M., Prajogi G.B., Giselvania A., Adham M., Hamid A.R.A.H., Widyastuti E., Prabowo Y., Aninditha T., Purwoto G., Aman R.A., Siregar T.P., Siswoyo A.D., Lisnawati, Handjari D.R., Atmakusuma D., Rajabto W., Mulansari N.A., Ratna N., Pitoyo C.W., Panigoro S.S., Kartini D., Yulian E.D., Andrisa R.S., Jeo W.S., Wardhani R.K., Tambunan T.F.U., Agianda F., Priyambodho |
6508327402;57217200193;57222017707;57222032883;57222015964;57195939736;57217198334;57222391312;56576294500;57221911632;57217201891;14024202100;57202054669;57222381718;56682042400;57189611205;14720170400;36848942500;57222017915;57210639278;24449072000;56160657900;23472246000;36519576100;36519326000;57222024187;26022606900;56790104300;57215490523;55983956600;57222018745;57201257973;57222033979;57222024180;57222019146;57222384319; |
Five-year cancer epidemiology at the nationa referral hospital: Hospital-based cancer registry data in Indonesia |
2021 |
JCO Global Oncology |
7 |
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190 |
203 |
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https://www.scopus.com/inward/record.uri?eid=2-s2.0-85101027387&doi=10.1200%2fGO.20.00155&partnerID=40&md5=60ffa9d74a039cb3543813b399bd6492 |
Department of Radiation Oncology, Faculty of Medicine, Universitas Indonesia-Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Department of Otorhinolaryngology, Faculty of Medicine, Universitas Indonesia-Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Department of Urology, Faculty of Medicine, Universitas Indonesia-Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Division of Hemato-Oncology, Department of Pediatrics, Faculty of Medicine, Universitas Indonesia-Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Department of Orthopedics, Faculty of Medicine, Universitas Indonesia-Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Division of Neuro-Oncology, Department of Neurology, Faculty of Medicine, Universitas Indonesia-Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, Faculty of Medicine, Universitas Indonesia-Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Department of Neurosurgery, Faculty of Medicine, Universitas Indonesia-Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Department of Radiology, Faculty of Medicine, Universitas Indonesia-Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Department of Anatomical Pathology, Faculty of Medicine, Universitas Indonesia-Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Division of Hematology-Oncology Medicine, Department of Internal Medicine, Faculty of Medicine, Universitas Indonesia-Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Department of Nutrition Science Clinic, Faculty of Medicine, Universitas Indonesia-Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Division of Respirology and Critical Illness, Department of Internal Medicine, Faculty of Medicine, Universitas Indonesia-Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Division of Oncology Surgery, Department of Surgery, Faculty of Medicine, Universitas Indonesia-Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Division of Eye Oncology, Department of Ophthalmology, Faculty of Medicine, Universitas Indonesia-Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Digestive Surgery Division, Department of Surgery, Faculty of Medicine, Universitas Indonesia-Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Department of Medical Rehabilitation, Faculty of Medicine, Universitas Indonesia-Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Department of Psychiatry, Faculty of Medicine, Universitas Indonesia-Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Department of Anesthesiology and Intensive Therapy, Faculty of Medicine, Universitas Indonesia-Cipto Mangunkusumo Hospital, Jakarta, Indonesia |
Gondhowiardjo, S., Department of Radiation Oncology, Faculty of Medicine, Universitas Indonesia-Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Christina, N., Department of Radiation Oncology, Faculty of Medicine, Universitas Indonesia-Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Ganapati, N.P.D., Department of Radiation Oncology, Faculty of Medicine, Universitas Indonesia-Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Hawariy, S., Department of Radiation Oncology, Faculty of Medicine, Universitas Indonesia-Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Radityamurti, F., Department of Radiation Oncology, Faculty of Medicine, Universitas Indonesia-Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Jayalie, V.F., Department of Radiation Oncology, Faculty of Medicine, Universitas Indonesia-Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Octavianus, S., Department of Radiation Oncology, Faculty of Medicine, Universitas Indonesia-Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Putra, A.P., Department of Radiation Oncology, Faculty of Medicine, Universitas Indonesia-Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Sekarutami, S.M., Department of Radiation Oncology, Faculty of Medicine, Universitas Indonesia-Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Prajogi, G.B., Department of Radiation Oncology, Faculty of Medicine, Universitas Indonesia-Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Giselvania, A., Department of Radiation Oncology, Faculty of Medicine, Universitas Indonesia-Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Adham, M., Department of Otorhinolaryngology, Faculty of Medicine, Universitas Indonesia-Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Hamid, A.R.A.H., Department of Urology, Faculty of Medicine, Universitas Indonesia-Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Widyastuti, E., Division of Hemato-Oncology, Department of Pediatrics, Faculty of Medicine, Universitas Indonesia-Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Prabowo, Y., Department of Orthopedics, Faculty of Medicine, Universitas Indonesia-Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Aninditha, T., Division of Neuro-Oncology, Department of Neurology, Faculty of Medicine, Universitas Indonesia-Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Purwoto, G., Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, Faculty of Medicine, Universitas Indonesia-Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Aman, R.A., Department of Neurosurgery, Faculty of Medicine, Universitas Indonesia-Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Siregar, T.P., Department of Radiology, Faculty of Medicine, Universitas Indonesia-Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Siswoyo, A.D., Department of Radiology, Faculty of Medicine, Universitas Indonesia-Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Lisnawati, Department of Anatomical Pathology, Faculty of Medicine, Universitas Indonesia-Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Handjari, D.R., Department of Anatomical Pathology, Faculty of Medicine, Universitas Indonesia-Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Atmakusuma, D., Division of Hematology-Oncology Medicine, Department of Internal Medicine, Faculty of Medicine, Universitas Indonesia-Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Rajabto, W., Division of Hematology-Oncology Medicine, Department of Internal Medicine, Faculty of Medicine, Universitas Indonesia-Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Mulansari, N.A., Division of Hematology-Oncology Medicine, Department of Internal Medicine, Faculty of Medicine, Universitas Indonesia-Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Ratna, N., Department of Nutrition Science Clinic, Faculty of Medicine, Universitas Indonesia-Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Pitoyo, C.W., Division of Respirology and Critical Illness, Department of Internal Medicine, Faculty of Medicine, Universitas Indonesia-Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Panigoro, S.S., Division of Oncology Surgery, Department of Surgery, Faculty of Medicine, Universitas Indonesia-Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Kartini, D., Division of Oncology Surgery, Department of Surgery, Faculty of Medicine, Universitas Indonesia-Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Yulian, E.D., Division of Oncology Surgery, Department of Surgery, Faculty of Medicine, Universitas Indonesia-Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Andrisa, R.S., Division of Eye Oncology, Department of Ophthalmology, Faculty of Medicine, Universitas Indonesia-Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Jeo, W.S., Digestive Surgery Division, Department of Surgery, Faculty of Medicine, Universitas Indonesia-Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Wardhani, R.K., Department of Medical Rehabilitation, Faculty of Medicine, Universitas Indonesia-Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Tambunan, T.F.U., Department of Medical Rehabilitation, Faculty of Medicine, Universitas Indonesia-Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Agianda, F., Department of Psychiatry, Faculty of Medicine, Universitas Indonesia-Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Priyambodho, Department of Anesthesiology and Intensive Therapy, Faculty of Medicine, Universitas Indonesia-Cipto Mangunkusumo Hospital, Jakarta, Indonesia |
PURPOSE In 2016, there were 1,308,061 cases of cancer being treated in Indonesia, with 2.2 trillion rupiahs spent, amounting to $486,960,633 in US dollars (purchasing power parity 2016). The high burden of cancers in Indonesia requires a valid data collection to inform future cancer-related policies. The purpose of this study is to report cancer epidemiological data from 2008 to 2012 based on Hospital-Based Cancer Registry (HBCR) data from Cipto Mangunkusumo Hospital, Indonesia. METHODS This was a descriptive study with cross-sectional design. Data were collected from Cipto Mangunkusumo Hospital HBCR 2008-2012. Demographical, diagnostic, stages of cancer, and histopathological types of cancer data were extracted. RESULTS After screening, 18,216 cases were included. A total of 12,438 patients were older than 39 years of age (68.3%), with a female-to-male ratio of 9:5. Most patients have cancers at advanced stages (stages III and IV, 10.2%). The most common sites of cancer were cervix uteri (2,878 cases, 15.8%), breast (2,459 cases, 13.5%), hematopoietic and reticuloendothelial systems (1,422 cases, 7.8%), nasopharynx (1,338 cases, 7.4%), and lymph nodes (1,104 cases, 6.1%). CONCLUSION From this HBCR, cancer incidence in female was almost twice the incidence in male, largely because of the burden of cervical and breast cancers. The cervix uteri as one of the top five cancer sites based on this HBCR, 2008-2012, are still approximately consistent with Global Cancer Incidence, Mortality and Prevalence 2018, which portrayed that Indonesia has been severely afflicted by cervical cancer cases more than any other Association of Southeast Asian Nations countries. The HBCR could serve as a robust database of epidemiological data for cancer cases in Indonesia. © 2021 by American Society of Clinical Oncology |
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adrenal cancer; adult; anus cancer; Article; articular cartilage; autonomic nervous system; bile duct cancer; bladder cancer; bone cancer; brain cancer; breast cancer; bronchus cancer; cancer diagnosis; cancer epidemiology; cancer incidence; cancer localization; cancer mortality; cancer of unknown primary site; cancer registry; cancer staging; cartilage cancer; central nervous system cancer; clinical examination; colon cancer; connective tissue cancer; cranial nerve cancer; cross-sectional study; demography; descriptive research; endocrine cancer; esophagus cancer; eye cancer; female; female genital tract cancer; gallbladder cancer; gingiva tumor; heart cancer; hematologic malignancy; hepatobiliary system cancer; histopathology; human; hypopharynx cancer; Indonesia; intrahepatic bile duct; |
American Society of Clinical Oncology |
26878941 |
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33539173 |
Article |
- |
0 |
32782 |
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875 |
Lim M.A., Kurniawan A.A. |
57216039756;57222011563; |
Dreadful Consequences of Sarcopenia and Osteoporosis due to COVID-19 Containment |
2021 |
Geriatric Orthopaedic Surgery and Rehabilitation |
12 |
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3 |
https://www.scopus.com/inward/record.uri?eid=2-s2.0-85101012807&doi=10.1177%2f2151459321992746&partnerID=40&md5=a0f3b09ec242d45be8f989650cec89a9 |
Faculty of Medicine, Universitas Pelita Harapan, Tangerang, Indonesia; Eminence Sports Medicine and Human Performance Center, Jakarta, Indonesia; Department of Sports Medicine, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia |
Lim, M.A., Faculty of Medicine, Universitas Pelita Harapan, Tangerang, Indonesia, Eminence Sports Medicine and Human Performance Center, Jakarta, Indonesia; Kurniawan, A.A., Eminence Sports Medicine and Human Performance Center, Jakarta, Indonesia, Department of Sports Medicine, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia |
[No abstract available] |
Fragility Fractures; Geriatric Trauma; Metabolic Bone disorders; Osteoporosis; Sarcopenia |
vitamin D; absorptiometry; anthropometry; bone density; bone fragility; coronavirus disease 2019; dietary intake; dual energy X ray absorptiometry; fracture nonunion; fracture risk assessment; fragility fracture; health care personnel; hip fracture; Letter; lifestyle modification; musculoskeletal injury; osteomyelitis; osteopenia; osteoporosis; physical activity; physical performance; quality of life; sarcopenia; vitamin supplementation |
SAGE Publications Inc. |
21514585 |
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Letter |
- |
0 |
32716 |
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876 |
Sari I.P., Audindra S., Zhafira A.S., Rahma A.A., Syarira C.V., Wahdini S. |
57197543698;57222006228;57205515532;57222005612;57222010715;57203684068; |
Nutritional status of school-aged children with intestinal parasite infection in South Jakarta, Indonesia |
2021 |
Open Access Macedonian Journal of Medical Sciences |
9 |
E |
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95 |
100 |
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3 |
https://www.scopus.com/inward/record.uri?eid=2-s2.0-85100938719&doi=10.3889%2foamjms.2021.5711&partnerID=40&md5=1772780d39afba8ba66dd65e8997f0b4 |
Department of Parasitology, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Undergraduate Program in Medical Doctor, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia |
Sari, I.P., Department of Parasitology, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Audindra, S., Undergraduate Program in Medical Doctor, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Zhafira, A.S., Undergraduate Program in Medical Doctor, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Rahma, A.A., Undergraduate Program in Medical Doctor, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Syarira, C.V., Undergraduate Program in Medical Doctor, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Wahdini, S., Department of Parasitology, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia |
BACKGROUND: The prevalence of intestinal parasitic infection still high in Indonesia and lead to nutritional disorder, especially in the school-aged children. AIM: This research conducted to find the association of intestinal parasitic infection to the nutritional status of the children. METHODS: This was a cross sectional study, conducted in January 2016 in one primary school in South Jakarta, Jakarta, Indonesia, by collecting the children’s stool from 1st to 5th grade. Direct examination of the stool was conducted in the Parasitology Department, Faculty of Medicine, Universitas Indonesia, by Lugol and eosin staining. Nutritional status categorized using BMI chart. Data were analyzed using Chi-square test, Statistical Product, and Service Solutions version 20. RESULTS: From the total 157 stool examined in the laboratory, there were 60 (38.2%) children positively infected with various kinds of intestinal parasites. Mostly the infection is caused by Blastocystis hominis, which infects 44 children (69.4%). The other infection is caused by Giardia lamblia (15.3%), Trichuris trichiura (1.4%), and hookworm (1.4%), and mixed infection of B. hominis and Escherichia coli (4.2%) and B. hominis with G. lamblia (4.2%). From the total of infected children, 17 children (28.3%) have BMI below 5th percentile, and it was considered as malnourished. Moreover, 67 uninfected children have normal nutritional status. Statistically, there is an association between intestinal parasitic infection and nutritional status in school-aged children in South Jakarta (P < 0.05). CONCLUSION: The incidence of intestinal parasitic infection in school-aged children is 38.2%. Moreover, 28.3% of the infected children were malnourished and it is suggested that children with intestinal parasite infection have low nutritional status. © 2021 Ika Puspa Sari, Sacha Audindra, Aqila S. Zhafira, Arin A. Rahma, Cut V. Syarira, Sri Wahdini. |
Malnourish; Parasitic Infection; Primary Schools; South Jakarta |
Article; Blastocystis hominis; body mass; child; cross-sectional study; disease association; Escherichia coli; feces analysis; female; Giardia intestinalis; human; Indonesia; intestine parasite; major clinical study; male; malnutrition; mixed infection; nutritional status; obesity; parasitosis; prevalence; primary school; questionnaire; seasonal variation; Trichuris trichiura; underweight |
Open Access Macedonian Journal of Medical Sciences |
18579655 |
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Article |
Q3 |
288 |
15252 |
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877 |
Negara J.D.K., Mudjianto S., Budikayanti A., Adhitya Nugraha P.P. |
57221389254;57193794731;57194713932;57221981778; |
The effect of gamma wave optimization and attention on hitting skills in softball |
2021 |
International Journal of Human Movement and Sports Sciences |
9 |
1 |
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103 |
109 |
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https://www.scopus.com/inward/record.uri?eid=2-s2.0-85100846277&doi=10.13189%2fsaj.2021.090114&partnerID=40&md5=572b9a6bf2d4f86222486dfb5b12188a |
Department of Sport Education, Faculty of Sport Education and Health, Universitas Pendidikan Indonesia, Bandung, West Java, 40154, Indonesia; Department of Neurology, Faculty of Medicine, Universitas Indonesia, Jakarta, 10440, Indonesia |
Negara, J.D.K., Department of Sport Education, Faculty of Sport Education and Health, Universitas Pendidikan Indonesia, Bandung, West Java, 40154, Indonesia; Mudjianto, S., Department of Sport Education, Faculty of Sport Education and Health, Universitas Pendidikan Indonesia, Bandung, West Java, 40154, Indonesia; Budikayanti, A., Department of Neurology, Faculty of Medicine, Universitas Indonesia, Jakarta, 10440, Indonesia; Adhitya Nugraha, P.P., Department of Sport Education, Faculty of Sport Education and Health, Universitas Pendidikan Indonesia, Bandung, West Java, 40154, Indonesia |
Hitting the ball is a complicated ability in softball academicie, because in appreciation to prioritizing movement skills, cognitive appearances additionally need to be investigated, one of which is attention. Meanwhile, going to hit the ball requires excellent attention for an individual student. Exhibiting gamma waves further influence arrangements of hitting performance. The objectives of this study were first, to determine the negative functional correlation between gamma brain waves and hitting skills, then second to know the positive functional correlation between attention and hitting skills and third to determine the effect of attention on increasing hitting skills. The method used in this research is an experimental method with a one-group pretest-posttest design research design. The sampling technique in this study was using a saturated sampling technique. This investigation amounted to 20 subjects, in the calculation of the Pearson product-moment correlation test using SPSS v.23. The first results collected were p-value 0.026 with an r square value of 0.25, so there is a significant negative functional correlation between gamma brain waves and hitting skills in softball learning of 25%. The second issue obtained p-value 0.017 with an r square value of 0.28, so there is a significant positive functional correlation between attention and hitting skills in softball learning by 28%. Furthermore, thirdly, the results obtained p-value 0.0001 between pre-test and post-test, with a significant increase in skills of 70.17%, so there is a significant influence between attention and hitting skills. © 2021 by authors, all rights reserved. |
Attention; Gamma Brain Waves; Hitting Skills; Softball Games |
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Horizon Research Publishing |
23814381 |
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Article |
Q4 |
132 |
25155 |
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878 |
Sitohang I.B.S., Rheza A.M., Sirait S.P., Fitri E.M., Suseno L.S. |
56734569200;57221927642;56426927400;57221929310;57202804092; |
Acne Vulgaris Mimicking Cutaneous Lupus Erythematosus in an Adolescent: Report of a Rare Case |
2021 |
Case Reports in Dermatology |
13 |
1 |
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69 |
74 |
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https://www.scopus.com/inward/record.uri?eid=2-s2.0-85100667271&doi=10.1159%2f000511530&partnerID=40&md5=e670f0805c017b254cadf2cd24514e56 |
Department of Dermatology and Venereology, Faculty of Medicine, Universitas Indonesia, Dr. Cipto Mangunkusumo Hospital, Jalan Salemba No. 6, Jakarta, 10430, Indonesia |
Sitohang, I.B.S., Department of Dermatology and Venereology, Faculty of Medicine, Universitas Indonesia, Dr. Cipto Mangunkusumo Hospital, Jalan Salemba No. 6, Jakarta, 10430, Indonesia; Rheza, A.M., Department of Dermatology and Venereology, Faculty of Medicine, Universitas Indonesia, Dr. Cipto Mangunkusumo Hospital, Jalan Salemba No. 6, Jakarta, 10430, Indonesia; Sirait, S.P., Department of Dermatology and Venereology, Faculty of Medicine, Universitas Indonesia, Dr. Cipto Mangunkusumo Hospital, Jalan Salemba No. 6, Jakarta, 10430, Indonesia; Fitri, E.M., Department of Dermatology and Venereology, Faculty of Medicine, Universitas Indonesia, Dr. Cipto Mangunkusumo Hospital, Jalan Salemba No. 6, Jakarta, 10430, Indonesia; Suseno, L.S., Department of Dermatology and Venereology, Faculty of Medicine, Universitas Indonesia, Dr. Cipto Mangunkusumo Hospital, Jalan Salemba No. 6, Jakarta, 10430, Indonesia |
Acne vulgaris is a chronic and self-limiting disorder of the pilosebaceous unit which is primarily seen in adolescents. Acne vulgaris presents as polymorphic lesions, consisting of comedones, papules, pustules, cysts, nodules, scarring, and dyspigmentation. Acneiform presentation of cutaneous lupus erythematosus (CLE) is extremely rare. The presentation of CLE is notoriously diverse and often mimics a broad range of unrelated skin disorders. We present a case by referring to American College of Rheumatology (ACR) criteria for systemic lupus erythematosus (SLE); our patient's conditions did not meet any of the clinical criteria of the Systemic Lupus International Collaborating Clinics (SLICC) for SLE. Subsequent to thorough history-taking, physical examination, and laboratory evaluations, the diagnosis of acne vulgaris was established, and a diagnosis of CLE was excluded. As acneiform presentation of CLE is rare, we here present a case which resembled both acne vulgaris and CLE. We describe our experience in establishing the diagnosis of severe acne vulgaris accompanied by scars in a 12-year-old boy with a malar rash and scars on his frontal and malar area who had initially been misdiagnosed as having CLE. This unusual case highlights the broad spectrum of adolescent acne and the importance of clinical identification of the disease so that unnecessary workups might be avoided. © 2021 |
Adolescent; Cutaneous lupus erythematosus; Severe acne vulgaris |
2 hydroxyacid; antinuclear antibody; benzoyl peroxide; clindamycin; complement component C3; glycolic acid; retinoic acid; triamcinolone acetonide; acne; acne vulgaris; adolescent; Article; brain spongiosis; case report; child; clinical article; comedo; diagnostic error; epiluminescence microscopy; erythema; follow up; histopathology; human; human tissue; hyperpigmentation; hypertrophic scar; immunofluorescence; male; papule; physical examination; pustule; rash; scar; school child; skin biopsy; skin defect; skin lupus erythematosus; systemic lupus erythematosus; urinalysis |
S. Karger AG |
16626567 |
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Article |
Q3 |
338 |
13690 |
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879 |
Sitohang I.B.S., Parrol F., Fitri E.M., Nora R.L.D. |
56734569200;57221938934;57221929310;57216253806; |
Papulopustular and Ocular Rosacea with an Alleged Coincidence of Cutaneous Lupus Erythematosus: A Case Report |
2021 |
Case Reports in Dermatology |
13 |
1 |
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62 |
68 |
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https://www.scopus.com/inward/record.uri?eid=2-s2.0-85100608017&doi=10.1159%2f000511495&partnerID=40&md5=d9521d968dd743848325d6f5df3a4bf9 |
Department of Dermatology and Venereology, Faculty of Medicine, Universitas Indonesia, Dr. Cipto Mangunkusumo Hospital, Jalan Salemba No. 6, Jakarta, 10430, Indonesia; Department of Ophthalmology, Faculty of Medicine, Universitas Indonesia, Dr. Cipto Mangunkusumo Hospital, Jakarta, Indonesia |
Sitohang, I.B.S., Department of Dermatology and Venereology, Faculty of Medicine, Universitas Indonesia, Dr. Cipto Mangunkusumo Hospital, Jalan Salemba No. 6, Jakarta, 10430, Indonesia; Parrol, F., Department of Dermatology and Venereology, Faculty of Medicine, Universitas Indonesia, Dr. Cipto Mangunkusumo Hospital, Jalan Salemba No. 6, Jakarta, 10430, Indonesia; Fitri, E.M., Department of Dermatology and Venereology, Faculty of Medicine, Universitas Indonesia, Dr. Cipto Mangunkusumo Hospital, Jalan Salemba No. 6, Jakarta, 10430, Indonesia; Nora, R.L.D., Department of Ophthalmology, Faculty of Medicine, Universitas Indonesia, Dr. Cipto Mangunkusumo Hospital, Jakarta, Indonesia |
Rosacea is a chronic inflammatory skin disease characterized by central facial erythema with or without ocular involvement. It is often difficult to distinguish rosacea from other malar rashes, one of which is acute cutaneous lupus erythematosus (CLE), particularly when there is an increase in antinuclear antibody (ANA) level. We report the case of a 16-year old woman with facial erythematous plaque accompanied by papules and pustules, reddened eyes, and swollen eyelids since the last one year. Dermoscopic examination revealed telangiectasia, and skin scraping examination with 20% potassium hydroxide identified the presence of Demodex folliculorum. Further ocular examination also revealed blepharitis, dysfunction of Meibomian gland, cicatrix, and corneal neovascularization. The ANA titer was positive (1:320), while the anti-dsDNA was negative. The patient was treated according to standard treatment for rosacea. The patient showed a satisfactory response following 2 weeks of therapy. Signs of recurring red patches with papules, pustules, telangiectasia, and identification of D. folliculorum on skin scraping examination led to the diagnosis of papulopustular rosacea. A positive ANA test may also be present in other diseases, e.g. acute CLE. Therefore, the diagnosis of rosacea remains a challenge. Thorough observation and examination must be done in order to yield an accurate diagnosis of rosacea. © 2021 |
Case report; Cutaneous lupus erythematosus; Ocular rosacea; Papulopustular rosacea |
adapalene; antinuclear antibody; doxycycline; hydroxychloroquine; metronidazole; nitric oxide; potassium hydroxide; rheumatoid factor; abdominal pain; adolescent; anemia; arthralgia; Article; blepharitis; case report; clinical article; conjunctival hyperemia; conjunctivitis; cornea neovascularization; Demodex; Demodex folliculorum; dermatitis; dyspnea; eye examination; face erythema; female; food intake; hair loss; headache; histopathology; human; meibomian gland; oxidative stress; papule; periorbital edema; psoriasis; psoriatic arthritis; pustule; rosacea; scar; skin biopsy; skin defect; sun exposure; systemic lupus erythematosus; telangiectasia |
S. Karger AG |
16626567 |
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Article |
Q3 |
338 |
13690 |
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880 |
Putri T.P., Dewi I.A.T.K., Permata T.B.M., Nuryadi E., Kodrat H., Wibowo H., Louisa M., Gondhowiardjo S.A. |
57221919322;57221917792;57197808751;57197806814;57210639849;57217690943;41461551400;6508327402; |
A mini systematic review: Eucheuma cottonii, a red algae, as a radiosensitizer? |
2021 |
Tropical Journal of Natural Product Research |
5 |
1 |
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7 |
15 |
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https://www.scopus.com/inward/record.uri?eid=2-s2.0-85100549316&doi=10.26538%2ftjnpr%2fv5i1.2&partnerID=40&md5=0849f73cb51c327672dca7dbaca3460f |
Department of Radiation Oncology, Dr. Cipto Mangunkusumo National General Hospital, Faculty of Medicine Universitas Indonesia, Jakarta, Indonesia; Diagnostic and Research Center, Faculty of Medicine Universitas Indonesia, Jakarta, Indonesia; Department of Pharmacology and Therapeutic, Faculty of Medicine Universitas Indonesia, Jakarta, Indonesia |
Putri, T.P., Department of Radiation Oncology, Dr. Cipto Mangunkusumo National General Hospital, Faculty of Medicine Universitas Indonesia, Jakarta, Indonesia; Dewi, I.A.T.K., Department of Radiation Oncology, Dr. Cipto Mangunkusumo National General Hospital, Faculty of Medicine Universitas Indonesia, Jakarta, Indonesia; Permata, T.B.M., Department of Radiation Oncology, Dr. Cipto Mangunkusumo National General Hospital, Faculty of Medicine Universitas Indonesia, Jakarta, Indonesia; Nuryadi, E., Department of Radiation Oncology, Dr. Cipto Mangunkusumo National General Hospital, Faculty of Medicine Universitas Indonesia, Jakarta, Indonesia; Kodrat, H., Department of Radiation Oncology, Dr. Cipto Mangunkusumo National General Hospital, Faculty of Medicine Universitas Indonesia, Jakarta, Indonesia; Wibowo, H., Diagnostic and Research Center, Faculty of Medicine Universitas Indonesia, Jakarta, Indonesia; Louisa, M., Department of Pharmacology and Therapeutic, Faculty of Medicine Universitas Indonesia, Jakarta, Indonesia; Gondhowiardjo, S.A., Department of Radiation Oncology, Dr. Cipto Mangunkusumo National General Hospital, Faculty of Medicine Universitas Indonesia, Jakarta, Indonesia |
Radiosensitizers assist radiotherapy in providing greater tumor inactivation. Currently there is a search for natural radiosensitizer components which are expected to provide lesser side effects than chemical radiosensitizers. Eucheuma cottonii is a plant with antioxidant and anti-tumor effects. This review aims to search for the potential use of Eucheuma cottonii as a radiosensitizer. This is a mixed review study, where the main component is a systematic review and then followed by a narrative review. This review suggests that Eucheuma cottonii has the potential to become a radiosensitizer, by interfering with the cell cycle control mechanisms and reactivation of p53. Further research is needed to explore the synergistic effect of the combined use of radiotherapy and Eucheuma cottonii. © 2021 Putri et al. |
Anti-tumour; Eucheuma cottonii; Immunomodulator; Radiosensitizer |
antineoplastic agent; birc5 protein; carrageenan; CD4 antigen; CD8 antigen; checkpoint kinase 1; cyclin dependent kinase inhibitor; Eucheuma cottonii extract; gamma interferon; immunomodulating agent; interleukin 4; mouse double minute 2 homolog; plant extract; programmed death 1 ligand 1; protein bcl 2; protein p21; protein p53; radiosensitizing agent; survivin; unclassified drug; antiapoptotic activity; antineoplastic activity; antioxidant activity; antiproliferative activity; apoptosis; cancer cell line; cell cycle regulation; cytotoxicity; gene expression; human; IC50; in vitro study; in vivo study; Kappaphycus alvarezii; MTT assay; neoplasm; nonhuman; phagocytosis; protein expression; radiosensitization; randomized controlled trial (topic); Review; synergistic effect; systematic revie |
Faculty of Pharmacy, University of Benin |
26160684 |
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Review |
Q4 |
127 |
25832 |
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