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No records
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704 |
Setiani R.U., Batubara E.A.D., Adiarto S., Siddiq T., Indriani S., Siahaan I.H. |
57277340700;57220786003;8603606800;57206239827;57213831064;57278163100; |
Successful Ovarian Vein Embolization of a Multiparous Woman with Pelvic Congestion Syndrome |
2021 |
International Journal of Angiology |
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https://www.scopus.com/inward/record.uri?eid=2-s2.0-85115934784&doi=10.1055%2fs-0041-1731272&partnerID=40&md5=3d3e2b558ea0c0ec2f0afad82a5a9503 |
Department of Cardiology and Vascular Medicine, National Cardiovascular Centre Harapan Kita, Faculty of Medicine, Universitas Indonesia, Jakarta, 11420, Indonesia; Department of Cardiology and Vascular Medicine, Persahabatan Public Hospital, Jakarta, Indonesia |
Setiani, R.U., Department of Cardiology and Vascular Medicine, National Cardiovascular Centre Harapan Kita, Faculty of Medicine, Universitas Indonesia, Jakarta, 11420, Indonesia; Batubara, E.A.D., Department of Cardiology and Vascular Medicine, National Cardiovascular Centre Harapan Kita, Faculty of Medicine, Universitas Indonesia, Jakarta, 11420, Indonesia; Adiarto, S., Department of Cardiology and Vascular Medicine, National Cardiovascular Centre Harapan Kita, Faculty of Medicine, Universitas Indonesia, Jakarta, 11420, Indonesia; Siddiq, T., Department of Cardiology and Vascular Medicine, National Cardiovascular Centre Harapan Kita, Faculty of Medicine, Universitas Indonesia, Jakarta, 11420, Indonesia; Indriani, S., Department of Cardiology and Vascular Medicine, National Cardiovascular Centre Harapan Kita, Faculty of Medicine, Universitas Indonesia, Jakarta, 11420, Indonesia; Siahaan, I.H., Department of Cardiology and Vascular Medicine, Persahabatan Public Hospital, Jakarta, Indonesia |
Pelvic congestion syndrome (PCS) is a clinical syndrome supported by specific findings, such as ovarian vein's dilatation, that cause pelvic vein congestion. Although many theories are explaining the pathophysiologies of this condition, the underlying cause remains unknown. The clinical manifestations of PCS are various including chronic pelvic pain (CPP), voiding disturbances, or ureteral obstruction. Imaging modality, such as ultrasonography, computed tomography (CT scan), magnetic resonance imaging (MRI), and venography, are needed to confirm and exclude the differential diagnosis. Currently, American venous forum guidelines recommended endovascular therapy which is percutaneous embolization as the first option therapy of PCS. Here, we reported a 35-year-old woman with PCS who underwent successful percutaneous embolization therapy. © 2021. International College of Angiology. All rights reserved. |
chronic pelvic pain; multiparous woman; pelvic congestion syndrome; percutaneous embolization; venography |
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Thieme Medical Publishers, Inc. |
10611711 |
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Article |
Q3 |
293 |
15070 |
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899 |
Tanto I.V., Dharma S., Juzar D.A., Bono A.A.H. |
57221612652;55101301700;55358712500;57208146721; |
Ventricular Septal Rupture Complicating an Acute ST-Segment Elevation Myocardial Infarction during the COVID-19 Pandemic |
2021 |
International Journal of Angiology |
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https://www.scopus.com/inward/record.uri?eid=2-s2.0-85099596441&doi=10.1055%2fs-0040-1720971&partnerID=40&md5=aab866db219c647750534315d55f3fdf |
Department of Cardiology and Vascular Medicine, Faculty of Medicine, University of Indonesia, Indonesian Cardiovascular Research Center, National Cardiovascular Center Harapan Kita, Jl S Parman Kav 87, Slipi, Jakarta Barat, Jakarta, 11420, Indonesia; Division of Cardiothoracic and Vascular Surgery, National Cardiovascular Center Harapan Kita, Jakarta, Indonesia |
Tanto, I.V., Department of Cardiology and Vascular Medicine, Faculty of Medicine, University of Indonesia, Indonesian Cardiovascular Research Center, National Cardiovascular Center Harapan Kita, Jl S Parman Kav 87, Slipi, Jakarta Barat, Jakarta, 11420, Indonesia; Dharma, S., Department of Cardiology and Vascular Medicine, Faculty of Medicine, University of Indonesia, Indonesian Cardiovascular Research Center, National Cardiovascular Center Harapan Kita, Jl S Parman Kav 87, Slipi, Jakarta Barat, Jakarta, 11420, Indonesia; Juzar, D.A., Department of Cardiology and Vascular Medicine, Faculty of Medicine, University of Indonesia, Indonesian Cardiovascular Research Center, National Cardiovascular Center Harapan Kita, Jl S Parman Kav 87, Slipi, Jakarta Barat, Jakarta, 11420, Indonesia; Bono, A.A.H., Division of Cardiothoracic and Vascular Surgery, National Cardiovascular Center Harapan Kita, Jakarta, Indonesia |
Ventricular septal rupture (VSR) is rare but a lethal complication of acute myocardial infarction (MI). Definite treatment requires the surgical closure of the VSR and coronary artery bypass grafting (CABG). However, the optimal timing for surgery is still controversial, particularly during the novel coronavirus disease 2019 (COVID-19) pandemic where medical procedures should be performed within the safest environment. Before surgery, a proper management in the intensive cardiovascular care unit is essential to maintain the stability of the hemodynamic profile related with VSR and determines the prognosis of the patient. We described a case of VSR complicating an anterior wall MI in a patient who admitted to our hospital during the COVID-19 pandemic that was treated successfully by surgical closure of the VSR and CABG. © 2021 BMJ Publishing Group. All rights reserved. |
bypass grafting; myocardial infarction; surgical repair; ventricular septal rupture |
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Thieme Medical Publishers, Inc. |
10611711 |
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Article |
Q3 |
293 |
15070 |
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No records
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709 |
Ayu Asri Prima Dewi A.A., Antarianto R.D., Pawitan J.A. |
57268721600;57190862806;6508348067; |
Characterization of indonesia decellularized liver cubes scaffold using scanning electron microscopy |
2021 |
Journal of Biomimetics, Biomaterials and Biomedical Engineering |
52 |
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38 |
46 |
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https://www.scopus.com/inward/record.uri?eid=2-s2.0-85115446740&doi=10.4028%2fwww.scientific.net%2fJBBBE.52.38&partnerID=40&md5=c7fc1ea62d3680df39cd8c77bf963ba1 |
Master Program in Biomedical Science, Faculty of Medicine, Universitas Indonesia, Jl Salemba Raya No 6, Senen, Central Jakarta, 10430, Indonesia; Department of Histology, Faculty of Medicine, Warmadewa University, Jl. Terompong 24 Tanjung Bungkak, Denpasar, Bali, Indonesia; Department of Histology, Faculty of Medicine, Universitas Indonesia, Jl Salemba Raya No 6, Senen, Central Jakarta, 10430, Indonesia; Stem Cell and Tissue Engineering Research Cluster, Indonesian Medical Education and Research Institute, Faculty of Medicine, Universitas Indonesia, Jl Salemba Raya No 6, Senen, Central Jakarta, 10430, Indonesia; Integrated Stem Cell Technology Service Unit, Cipto Mangunkusumo National General Hospital, Jl. Diponegoro No.71, Salemba, Jakarta, Indonesia |
Ayu Asri Prima Dewi, A.A., Master Program in Biomedical Science, Faculty of Medicine, Universitas Indonesia, Jl Salemba Raya No 6, Senen, Central Jakarta, 10430, Indonesia, Department of Histology, Faculty of Medicine, Warmadewa University, Jl. Terompong 24 Tanjung Bungkak, Denpasar, Bali, Indonesia; Antarianto, R.D., Department of Histology, Faculty of Medicine, Universitas Indonesia, Jl Salemba Raya No 6, Senen, Central Jakarta, 10430, Indonesia, Stem Cell and Tissue Engineering Research Cluster, Indonesian Medical Education and Research Institute, Faculty of Medicine, Universitas Indonesia, Jl Salemba Raya No 6, Senen, Central Jakarta, 10430, Indonesia; Pawitan, J.A., Department of Histology, Faculty of Medicine, Universitas Indonesia, Jl Salemba Raya No 6, Senen, Central Jakarta, 10430, Indonesia, Stem Cell and Tissue Engineering Research Cluster, Indonesian Medical Education and Research Institute, Faculty of Medicine, Universitas Indonesia, Jl Salemba Raya No 6, Senen, Central Jakarta, 10430, Indonesia, Integrated Stem Cell Technology Service Unit, Cipto Mangunkusumo National General Hospital, Jl. Diponegoro No.71, Salemba, Jakarta, Indonesia |
Liver biological scaffold was developed in order to resemble native liver tissue environment. It can be achieved by decellularizing native liver tissue that will remove cells and preserve extracellular matrix (ECM). Furthermore, ECM fibers are arranged in a special pattern, which affect liver cell polarity and topography that are important for cells’ implantation, proliferation and differentiation. Therefore, the aim of this study was to evaluate liver cube scaffold topography that was decellularized with fixed multiple sites syringe injection (Indonesia patent number: S00201907930). Rat liver cubes (n=3) underwent decellularization with Ethylene Glycol Tetraacetic Acid (EGTA) immersion and increased Sodium Dodecyl Sulfate (SDS) concentrations using previous multiple sites syringe injection protocol study. Deoxyribonucleic Acid (DNA) concentrations were measured to confirm less DNA materials remaining in scaffolds. Scanning Electron Microscope (SEM) analysis of scaffolds were conducted for topographic characterization compared to undecellularized liver control. Molecular analysis of DNA concentration showed complete removal of DNA material. SEM analysis gave appearance of intact liver cube scaffold microarchitecture. Liver cubes decellularization using multiple sites syringe injection showed good topographic liver scaffold characterization. © 2021 Trans Tech Publications Ltd, Switzerland. |
Liver biological scaffold; Liver cube tissue; Liver decellularization; Multiple site syringe injection; Scanning electron microscope |
Cytology; DNA; Ethylene; Ethylene glycol; Geometry; Scaffolds (biology); Sodium dodecyl sulfate; Sulfur compounds; Syringes; Tissue; Acid concentrations; Biological scaffolds; Decellularization; Extracellular matrices; Indonesia; Liver biological scaffold; Liver cube tissue; Liver decellularization; Liver tissue; Multiple site syringe injection; Scanning electron microscopy |
Trans Tech Publications Ltd |
22969837 |
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Article |
Q4 |
183 |
20493 |
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710 |
Putrantyo I., Anilbhai N., Vanjani R., De Vega B. |
57268843400;57268843500;57268728700;57222467939; |
Tantalum as a novel biomaterial for bone implant: A literature review |
2021 |
Journal of Biomimetics, Biomaterials and Biomedical Engineering |
52 |
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55 |
65 |
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1 |
https://www.scopus.com/inward/record.uri?eid=2-s2.0-85115443615&doi=10.4028%2fwww.scientific.net%2fJBBBE.52.55&partnerID=40&md5=23de679861db060839b35e7a1cc36b26 |
Division of Surgery and Interventional Science, University College London, Royal Free Hospital Campus, London, United Kingdom; Faculty of Medicine Universitas Indonesia, Dr Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Cell & Tissue Bank, Dr Soetomo General Hospital, Surabaya, Indonesia |
Putrantyo, I., Division of Surgery and Interventional Science, University College London, Royal Free Hospital Campus, London, United Kingdom, Faculty of Medicine Universitas Indonesia, Dr Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Anilbhai, N., Division of Surgery and Interventional Science, University College London, Royal Free Hospital Campus, London, United Kingdom; Vanjani, R., Division of Surgery and Interventional Science, University College London, Royal Free Hospital Campus, London, United Kingdom; De Vega, B., Division of Surgery and Interventional Science, University College London, Royal Free Hospital Campus, London, United Kingdom, Cell & Tissue Bank, Dr Soetomo General Hospital, Surabaya, Indonesia |
Titanium (Ti) has been used in metallic implants since the 1950s due to various biocompatible and mechanical properties. However, due to its high Young’s modulus, it has been modified over the years in order to produce a better biomaterial. Tantalum (Ta) has recently emerged as a new potential biomaterial for bone and dental implants. It has been reported to have better corrosion resistance and osteo-regenerative properties as compared to Ti alloys which are most widely used in the bone-implant industry. Currently, Tantalum cannot be widely used yet due to its limited availability, high melting point, and high-cost production. This review paper discusses various manufacturing methods of Tantalum alloys, including conventional and additive manufacturing and also discusses their drawbacks and shortcomings. Recent research includes surface modification of various metals using Tantalum coatings in order to combine bulk material properties of different materials and the porous surface properties of Tantalum. Design modification also plays a crucial role in controlling bulk properties. The porous design does provide a lower density, wider surface area, and more immense specific strength. In addition to improved mechanical properties, a porous design could also escalate the material's biological and permeability properties. With current advancement in additive manufacturing technology, difficulties in processing Tantalum could be resolved. Therefore, Tantalum should be considered as a serious candidate material for future bone and dental implants. © 2021 Trans Tech Publications Ltd, Switzerland. |
Bone implant; Porous metal; Porous structure; Surface coating; Tantalum |
3D printers; Additives; Biocompatibility; Coatings; Corrosion resistant alloys; Dental alloys; Dental prostheses; Mechanical permeability; Metal implants; Porosity; Tantalum alloys; Titanium alloys; Bone implant; High costs; High melting point; Literature reviews; Metallic implants; Porous metal; Porous structures; Property; Surface coatings; Titanium (alloys); Corrosion resistance |
Trans Tech Publications Ltd |
22969837 |
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Article |
Q4 |
183 |
20493 |
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863 |
Sahlan M., Tejamaya M., Arbianti R., Baruji T., Adawiyah R., Hermansyah H. |
57189182661;55295863200;55897945700;57222240819;57208658742;15759436800; |
The effects of nano-casein encapsulation and productions of a controlled-release on eugenol containing bio-pesticide toxicity |
2021 |
Key Engineering Materials |
874 KEM |
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115 |
127 |
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2 |
https://www.scopus.com/inward/record.uri?eid=2-s2.0-85101971950&doi=10.4028%2fwww.scientific.net%2fKEM.874.115&partnerID=40&md5=6f6b175ce47bb2305dfbaffecf2240a3 |
Department of Chemical Engineering, Faculty of Engineering, Universitas Indonesia, Depok, 16424, Indonesia; Research Center of Biomedical Engineering, Faculty of Engineering, Universitas Indonesia, Depok, 16424, Indonesia; Department of Occupational Health and Safety, Faculty of Public Health, Universitas Indonesia, Depok, 16424, Indonesia; Center of Bioindustry Technology, Agency for The Assessment and Application of Technology, Jakarta, 10340, Indonesia; Department of Parasitology, Faculty of Medicine, Universitas Indonesia, Jakarta, 10430, Indonesia |
Sahlan, M., Department of Chemical Engineering, Faculty of Engineering, Universitas Indonesia, Depok, 16424, Indonesia, Research Center of Biomedical Engineering, Faculty of Engineering, Universitas Indonesia, Depok, 16424, Indonesia; Tejamaya, M., Department of Occupational Health and Safety, Faculty of Public Health, Universitas Indonesia, Depok, 16424, Indonesia; Arbianti, R., Department of Chemical Engineering, Faculty of Engineering, Universitas Indonesia, Depok, 16424, Indonesia; Baruji, T., Center of Bioindustry Technology, Agency for The Assessment and Application of Technology, Jakarta, 10340, Indonesia; Adawiyah, R., Research Center of Biomedical Engineering, Faculty of Engineering, Universitas Indonesia, Depok, 16424, Indonesia, Department of Parasitology, Faculty of Medicine, Universitas Indonesia, Jakarta, 10430, Indonesia; Hermansyah, H., Department of Chemical Engineering, Faculty of Engineering, Universitas Indonesia, Depok, 16424, Indonesia |
The concern against long-term health and environmental adverse effects of synthetic pesticides has encouraged the development of bio-pesticides. Eugenol, a major constituent of clove oil, has been proven as potential bio-pesticides. However, evaporation and photosensitive properties of Eugenol needs to be controlled. Nano-encapsulation is a promising method that can preserve eugenol from evaporating and photodegradation. This study aims to investigate the production of a controlled-release of eugenol in casein micelle as well as the effects of nano-encapsulation on Eugenol Containing Biopesticide (ECB) toxicity against Artemia salina sp. Brine Shrimp Lethality Test (BSLT) was implemented to investigate effect of nano-encapsulation on ECB and the Response Surface Methodology was used to optimize the formula to investigate the production of a controlled-release of eugenol. The optimum condition revealed loading capacity and encapsulation efficiency response for 64.67% and 79.64%, respectively. The average diameter of the obtained nanocapsule-eugenol (NCE) was 179.83 nm. Release study was performed at 40 °C that represent as pesticide applied in farm, revealed that casein micelle capsule could delayed the release of eugenol. A cytotoxicity assay showed that the NCE has 21 times more effective compared with eugenol only. It was found that nano encapsulated ECB was statistically more toxic than ECBsuspension (without nano encapsulation) with a confidence level of 95%. Lethal Concentration 50 (LC50) of nano-ECB was 0.264 μg/L while LC50 of ECB-suspension was 4.445 μg/L. The increase of toxic properties after nano-encapsulation by casein could be explained by the increase of eugenol stability. Thus nano-encapsulation can be proposed as a method for improving the bio-pesticide ability of eugenol. © 2021 Trans Tech Publications Ltd, Switzerland. |
Biopesticide; BSLT1; Casein; Controlled-release; Eugenol; Nano encapsulation; Optimizing |
Casein; Dairies; Micelles; Suspensions (fluids); Toxicity; Brine shrimp lethalities; Cytotoxicity assays; Encapsulation efficiency; Investigate effects; Lethal concentration; Photosensitive properties; Response surface methodology; Synthetic pesticides; Pesticide effects |
Trans Tech Publications Ltd |
10139826 |
9783035737639 |
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Conference Paper |
Q4 |
175 |
21056 |
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No records
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326 |
Haerana B.T., Prihartono N.A., Riono P., Djuwita R., Syarif S., Hadi E.N., Kaswandani N. |
57219936737;6506739787;6507043370;56586138300;6504572251;57201912914;57195941745; |
Prevalence of tuberculosis infection and its relationship to stunting in children (under five years) household contact with new tuberculosis cases |
2021 |
Indian Journal of Tuberculosis |
68 |
3 |
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350 |
355 |
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https://www.scopus.com/inward/record.uri?eid=2-s2.0-85096164191&doi=10.1016%2fj.ijtb.2020.10.011&partnerID=40&md5=cda5d7332671c23afe12c476c778ae2e |
Department of Epidemiology, Faculty of Public Health, University of Indonesia, Indonesia; Department of Public Health, Universitas Islam Negeri Alauddin Makassar, Indonesia; Department of Biostatistics, Faculty of Public Health, University of Indonesia, Indonesia; Department of Health Education and Behavioral Sciences, University of Indonesia, Indonesia; Pediatric Department, RSCM Hospital, Faculty of Medicine, University of Indonesia, Indonesia |
Haerana, B.T., Department of Epidemiology, Faculty of Public Health, University of Indonesia, Indonesia, Department of Public Health, Universitas Islam Negeri Alauddin Makassar, Indonesia; Prihartono, N.A., Department of Epidemiology, Faculty of Public Health, University of Indonesia, Indonesia; Riono, P., Department of Biostatistics, Faculty of Public Health, University of Indonesia, Indonesia; Djuwita, R., Department of Epidemiology, Faculty of Public Health, University of Indonesia, Indonesia; Syarif, S., Department of Epidemiology, Faculty of Public Health, University of Indonesia, Indonesia; Hadi, E.N., Department of Health Education and Behavioral Sciences, University of Indonesia, Indonesia; Kaswandani, N., Pediatric Department, RSCM Hospital, Faculty of Medicine, University of Indonesia, Indonesia |
Background: Children who inhabit the same house with tuberculosis (TB) patients are at high risk for infection and illness with TB. Nutritional status (stunting) in children is related to the child's ability to withstand MTB (Mycobacterium Tuberculosis). This study aims to estimated the prevalence of tuberculosis infection and its relationship to stunting in children (under five years) with household contact (HHC) with new TB cases. Methods: A cross-sectional design was implemented. Conducted in July 2018–April 2019 at 13 Public Health Center in Makassar City. The sample size was calculated using one sample situation-about precision formula. Samples were children under five who had contact with new diagnosed TB cases. Tuberculosis infection was measured by TST (tuberculin skin test). Logistic regression with causal model to examine TB infection relationship with stunting and covariate variable, analyzed using Stata/MP 13.0 software. Results: One hundred twenty-six (126) eligible children. Prevalence of tuberculosis infection was 38.10%. Frequency of stunted was 31 children (24.60%). Stunted nutritional status (aPR): 2.36, 95% CI 1.60–3.44), boys (aPR: 1.47, 95% CI 0.96–2.25), not getting BCG immunization (aPR: 1.58, 95%) CI 0.89–2.82), and high contact intensity (aPR: 2.62, 95% CI 1.10–6.22) best predicted the tuberculosis infection in children with TB case household contacts with a model contribution of 64%. Conclusion: Stunted nutritional status (moderate and severe), boys, not getting BCG immunization, and high contact intensity are the determinants of TB infection transmission in children HHC with TB. Children under five years of age who have close contact with TB cases should be targeted for priority interventions to prevent the transmission of TB infection and progressing to TB cases. © 2020 Tuberculosis Association of India |
Children; Household contact; Tuberculosis infection |
Article; child; clinical assessment; clinical feature; controlled study; cross-sectional study; disease association; disease exacerbation; disease transmission; female; health program; household; human; immunization; infant; major clinical study; male; newborn; nutritional status; prevalence; prospective study; risk factor; stunting; tuberculin test; tuberculosis; contact examination; disease transmission; family size; growth disorder; Indonesia; isolation and purification; latent tuberculosis; malnutrition; Mycobacterium tuberculosis; pathogenicity; preschool child; prevention and control; procedures; risk assessment; tuberculosis; Child, Preschool; Contact Tracing; Cross-Sectional Studies; Disease Transmission, Infectious; Family Characteristics; Female; Growth Disorders; Humans; Indones |
Tuberculosis Association of India |
00195707 |
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34099200 |
Article |
Q3 |
376 |
12700 |
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No records
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858 |
Eldafira E., Prasasty V.D., Abinawanto A., Syahfirdi L., Pujianto D.A. |
57204963791;56019989700;55625129700;57222327356;8745734300; |
Polymorphisms of estrogen receptor-α and estrogen receptor-β genes and its expression in endometriosis [Östrojen reseptör-α ve östrojen reseptör-β genlerinin polimorfizmi ve endometriozisde ifadelenmeleri] |
2021 |
Turkish Journal of Pharmaceutical Sciences |
18 |
1 |
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91 |
95 |
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https://www.scopus.com/inward/record.uri?eid=2-s2.0-85102272548&doi=10.4274%2ftjps.galenos.2019.94914&partnerID=40&md5=ca75ed564cc74a659022ab862e0096b8 |
Universitas Indonesia, Faculty of Medicine, Department of Medical Biology, Depok, Indonesia; Universitas Indonesia, Faculty of Mathematics and Natural Sciences, Department of Biology, Jakarta, Indonesia; Atma Jaya Catholic University of Indonesia, Faculty of Biotechnology, Jakarta, Indonesia |
Eldafira, E., Universitas Indonesia, Faculty of Medicine, Department of Medical Biology, Depok, Indonesia, Universitas Indonesia, Faculty of Mathematics and Natural Sciences, Department of Biology, Jakarta, Indonesia; Prasasty, V.D., Atma Jaya Catholic University of Indonesia, Faculty of Biotechnology, Jakarta, Indonesia; Abinawanto, A., Universitas Indonesia, Faculty of Mathematics and Natural Sciences, Department of Biology, Jakarta, Indonesia; Syahfirdi, L., Universitas Indonesia, Faculty of Mathematics and Natural Sciences, Department of Biology, Jakarta, Indonesia; Pujianto, D.A., Universitas Indonesia, Faculty of Medicine, Department of Medical Biology, Depok, Indonesia |
Objectives: Endometriosis is a common gynecological disorder, characterized by the presence of endometrial-like tissue in the extrauterine location. The increasing estradiol concentration can influence endometriosis risk and estrogen receptor (ER) activity. Polymorphism in ER causes gene expression alteration and influences hormone-receptor interaction. This research aims to determine ER genetic polymorphisms in endometriosis pathogenesis. Materials and Methods: This study was performed on case-control polymorphisms, which compared 83 women with endometriosis and 76 women without endometriosis. However, the samples used for ER gene expression analysis and estrogen level measurement were obtained from 18 women with endometriosis and 18 women without endometriosis. Polymerase chain reaction-restriction fragment length polymorphism was used to determine ER genetic polymorphisms. Chi-square, Mann-Whitney test, Spearman’s correlation (p), t-independent, and two-tailed tests were used to analyze the data. Results: Association between the allele ERα rs9340799 A/G and endometriosis was significantly different (p=0.012), whereas rs2234693 T/C polymorphism showed no association with endometriosis. The correlation between the genotype frequencies of allele ERβ rs4986938 G/A and endometriosis was found significantly different (p=0.015; p=0.034). Conclusion: Estradiol level and ERβ expression increases, polymorphism genotypes and alleles of ERβ rs4986938 G/A gene and allele frequency of ERα rs9340799 A/G gene have roles in endometriosis. © Turk J Pharm Sci, Published by Galenos Publishing House. |
Endometriosis; Estradiol (E2); Estrogen receptor (ERα and ERβ) |
ammonium acetate; dodecyl sulfate sodium; estradiol; estrogen; estrogen receptor alpha; estrogen receptor beta; genomic DNA; adult; agar gel electrophoresis; allele; Article; case control study; centrifugation; controlled study; DNA extraction; DNA polymorphism; endometriosis; female; gene; gene amplification; gene frequency; genotype; human; illumination; intron; major clinical study; polymerase chain reaction; receptor gene; restriction fragment length polymorphism; rs2234693 gene; rs4986938 gene; spectrophotometry |
Turkish Pharmacists Association |
1304530X |
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Article |
Q3 |
241 |
17155 |
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No records
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781 |
Hidayat M., Handayani D., Nurwidya F., Andarini S.L. |
56435992700;57219413838;55221773800;8716259500; |
Hyperinflammation syndrome in covid-19 disease: Pathogenesis and potential immunomodulatory agents [Covid-19 hastalığında hiperenflamasyon sendromu: Patogenez ve potansiyel immünomodülatuvar ajanlar] |
2021 |
Turkish Journal of Immunology |
9 |
1 |
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1 |
11 |
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https://www.scopus.com/inward/record.uri?eid=2-s2.0-85108585451&doi=10.5222%2fTJI.2021.92486&partnerID=40&md5=e11fbb69c1d65d6dcdb052da54e5cf96 |
Faculty of Medicine, University of Mataram, Indonesia; Department of Pulmonology and Respiratory Medicine, Faculty of Medicine, Universitas Indonesia-Persahabatan Hospital, Jakarta, Indonesia |
Hidayat, M., Faculty of Medicine, University of Mataram, Indonesia; Handayani, D., Department of Pulmonology and Respiratory Medicine, Faculty of Medicine, Universitas Indonesia-Persahabatan Hospital, Jakarta, Indonesia; Nurwidya, F., Department of Pulmonology and Respiratory Medicine, Faculty of Medicine, Universitas Indonesia-Persahabatan Hospital, Jakarta, Indonesia; Andarini, S.L., Department of Pulmonology and Respiratory Medicine, Faculty of Medicine, Universitas Indonesia-Persahabatan Hospital, Jakarta, Indonesia |
The coronavirus disease 2019 (COVID-19) pandemic caused by infection of the SARS-CoV-2 virus has affected millions of people in the world. The pathogenesis and clinical manifestations of COVID-19 disease are tightly influenced by the host immune response to the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) virus. In some condition, the immune response might be uncontrolled, giving rise to hyperinflammatory conditions marked by excessive release of proinflammatory cytokines (cytokine storms) in severe COVID-19 patients, which then can cause acute respiratory distress syndrome (ARDS), multiorgan failure, and death. Furthermore, treatment using immunomodulator agents including immunostimulatory and immunosuppressive agents can be an option in achieving successful treatment. In this review, we discuss the pathogenesis of the disease, including host immune responses to SARS-CoV-2 virus infection, and immune mechanisms which contribute to the disease severity and death as well as several potential immunomodulatory agents which can be used in the management of hyperinflammatory syndrome of severe COVID-19. © Turkish Journal of Immunlogy. |
Coronavirus disease 2019 (COVID-19); Cytokine storm; Hyperinflammation syndrome; Immunomodulatory treatment |
chloroquine; convalescent plasma; hydroxychloroquine; immunoglobulin; immunomodulating agent; interferon; interleukin 1 receptor blocking agent; interleukin 6 antibody; neutralizing antibody; sarilumab; tocilizumab; tumor necrosis factor inhibitor; adult respiratory distress syndrome; antibody dependent enhancement; coronavirus disease 2019; cytokine production; cytokine release; cytokine storm; disease severity; human; hyperinflammatory syndrome; immune response; immune system; immunosuppressive treatment; mortality; multiple organ failure; pandemic; Review; Severe acute respiratory syndrome coronavirus 2; signal transduction; stem cell transplantation; virus cell interaction; virus pathogenesis; virus replication |
Turkish Society of Immunology |
1301109X |
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Review |
Q4 |
115 |
27813 |
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No records
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896 |
Suraya A., Nowak D., Sulistomo A.W., Icksan A.G., Berger U., Syahruddin E., Bose-O’reilly S. |
57214135787;7201764407;57024018500;57194332884;7101876991;6507688750;55933417800; |
Excess risk of lung cancer among agriculture and construction workers in Indonesia |
2021 |
Annals of Global Health |
87 |
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1 |
14 |
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1 |
https://www.scopus.com/inward/record.uri?eid=2-s2.0-85099767907&doi=10.5334%2faogh.3155&partnerID=40&md5=01b5a6cafe172bcea089864226c539b6 |
CIHLMU Center for International Health, University Hospital, LMU, Munich, Germany; Universitas Binawan, Jakarta, Indonesia; Institute and Outpatient Clinic for Occupational, Social and Environmental Medicine, LMU University Hospital, Munich, Germany; Comprehensive Pneumology Center Munich (CPC-M), Member, German Center for Lung Research (DZL), Germany; Department of Radiology, Persahabatan Hospital, National Respiratory Referral Hospital, Jakarta, Indonesia; Faculty of Medicine UPN Veteran, Jakarta, Indonesia; IBE – Institute for Medical Information Processing, Biometry and Epidemiology, LMU, Munich, Germany; Division of Thoracic Oncology Department of Pulmonology Faculty of Medicine, Universitas Indonesia Persahabatan hospital, Jakarta, Indonesia; Institute and Outpatient Clinic for Occupational, Social and Environmental Medicine, LMU University Hospital, Munich, Germany; Institute of Public Health, Medical Decision Making and Health Technology Assessment, Department of Public Health, Health Services Research and Health Technology Assessment, UMIT–Private University for Health Sciences, Medical Informatics and Technology, Austria |
Suraya, A., CIHLMU Center for International Health, University Hospital, LMU, Munich, Germany, Universitas Binawan, Jakarta, Indonesia; Nowak, D., Institute and Outpatient Clinic for Occupational, Social and Environmental Medicine, LMU University Hospital, Munich, Germany, Comprehensive Pneumology Center Munich (CPC-M), Member, German Center for Lung Research (DZL), Germany; Sulistomo, A.W., Universitas Binawan, Jakarta, Indonesia; Icksan, A.G., Department of Radiology, Persahabatan Hospital, National Respiratory Referral Hospital, Jakarta, Indonesia, Faculty of Medicine UPN Veteran, Jakarta, Indonesia; Berger, U., IBE – Institute for Medical Information Processing, Biometry and Epidemiology, LMU, Munich, Germany; Syahruddin, E., Division of Thoracic Oncology Department of Pulmonology Faculty of Medicine, Universitas Indonesia Persahabatan hospital, Jakarta, Indonesia; Bose-O’reilly, S., Institute and Outpatient Clinic for Occupational, Social and Environmental Medicine, LMU University Hospital, Munich, Germany, Institute of Public Health, Medical Decision Making and Health Technology Assessment, Department of Public Health, Health Services Research and Health Technology Assessment, UMIT–Private University for Health Sciences, Medical Informatics and Technology, Austria |
Background: In Indonesia, many occupations and industries involve a variety of hazardous and toxic materials. The ILO estimates that about 21.1% of the tracheal, bronchial, and lung cancer deaths among men were attributable to workplace hazardous substances. This study investigated the relationship between occupations or workplace exposure and the risk of lung cancer in the country. The results will help determine how Indonesia can best mitigate the risk for its workers. Objectives: This case-control study utilizes the Indonesian Standard of Industrial Classification (IndSIC) 2015 with the aim of exploring the risk of lung cancer among Indonesian workers. Methods: The study included patients aged 35 years old or older receiving thoracic CT at the radiology department of Persahabatan Hospital. The cases were histologicalconfirmed primary lung cancers, while the controls were negative thoracic CT scan for lung cancer. The subjects’ job titles and industries were classified according to IndSIC 2015 and blind to the patient’s grouping as a case or control. Logistic regression was used to determine the odds ratios for lung cancer among all sections and some divisions or groups of IndSIC 2015. Findings: The mean age was 58.1 (±10.23) years for lung cancer patients and 54.5 (±10.23) years for controls. The majority of subjects (19.6%) worked in Section G (Wholesale and retail trade; repair of motor vehicles and motorcycle). After adjusting for age, gender, level of education, and smoking habit, the risk of lung cancer was nearly three-times higher (OR = 2.8, 95% CI = 1.11–7.02) in workers of Division A01 (crop, animal production, and hunting) and two-times higher (OR = 1.9, 95% CI = 1.05–3.46) in workers of Section F (construction) compared to the workers in other sections or divisions. Conclusions: The excess risk of lung cancer among certain categories of workers confirms the need for improved policy, monitoring, and control of occupational exposure for primary cancer prevention and workers’ compensation purposes. © 2021 The Author(s). |
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adult; aged; agricultural worker; Article; cancer prevention; cancer risk; case control study; construction worker; controlled study; educational status; female; human; human tissue; Indonesia; lung cancer; major clinical study; male; medical information; motor vehicle; motorcycle; occupational exposure; occupational health; smoking habit; x-ray computed tomography; adverse event; agriculture; building industry; lung tumor; middle aged; occupation; occupational disease; occupational exposure; risk factor; very elderly; Adult; Aged; Aged, 80 and over; Agriculture; Case-Control Studies; Construction Industry; Female; Humans; Indonesia; Lung Neoplasms; Male; Middle Aged; Occupational Diseases; Occupational Exposure; Occupations; Risk Factors |
Ubiquity Press |
22149996 |
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33505867 |
Article |
Q2 |
602 |
8385 |
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795 |
Nadhif M.H., Irsyad M., Utomo M.S., Suhaeri M., Whulanza Y. |
57189057498;57220935587;56180933900;56183087500;36807053500; |
Computational Analysis of Soft Polymer Lattices for 3D Wound Dressing Materials |
2021 |
Journal of Mechanical Engineering |
18 |
2 |
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1 |
11 |
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2 |
https://www.scopus.com/inward/record.uri?eid=2-s2.0-85107456696&partnerID=40&md5=fb3bc81a587f3564de3a190ebd6e1a72 |
Department of Medical Physics, Faculty of Medicine, Universitas Indonesia, Indonesia; Medical Technology Cluster, Indonesia Medical Education and Research Institute (IMERI), Indonesia; Research Center for Metallurgy and Material, Indonesia Institute of Science (LIPI), Indonesia; Indonesia Unit of Education, Research and Training, Universitas Indonesia Hospital, Universitas Indonesia, Indonesia; Department of Mechanical Engineering, Faculty of Engineering Universitas, Indonesia; Research Center on Biomedical Engineering (RCBE), Faculty of Engineering Universitas, Indonesia |
Nadhif, M.H., Department of Medical Physics, Faculty of Medicine, Universitas Indonesia, Indonesia, Medical Technology Cluster, Indonesia Medical Education and Research Institute (IMERI), Indonesia; Irsyad, M., Medical Technology Cluster, Indonesia Medical Education and Research Institute (IMERI), Indonesia; Utomo, M.S., Department of Medical Physics, Faculty of Medicine, Universitas Indonesia, Indonesia, Medical Technology Cluster, Indonesia Medical Education and Research Institute (IMERI), Indonesia; Suhaeri, M., Medical Technology Cluster, Indonesia Medical Education and Research Institute (IMERI), Indonesia, Research Center for Metallurgy and Material, Indonesia Institute of Science (LIPI), Indonesia, Indonesia Unit of Education, Research and Training, Universitas Indonesia Hospital, Universitas Indonesia, Indonesia; Whulanza, Y., Department of Mechanical Engineering, Faculty of Engineering Universitas, Indonesia, Research Center on Biomedical Engineering (RCBE), Faculty of Engineering Universitas, Indonesia |
One of the wound treatments was negative pressure wound therapy (NPWT), which used wound dressings on the wound bed to ameliorate the wound healing. Unfortunately, most wound dressings were two dimensional (2D), lacking the ability to cover severe wounds with a straightforward procedure. The sheets needed to be stacked following the wound curvature, which might be problematic since improper stacking could hinder the wound healing. Regarding the mentioned problems, our group develop 3D wound dressings, which are made using 3D printers. The wound dressings are made of polycaprolactone (PCL), polyurethane (PU), and polyvinyl alcohol (PVA). As the initial stage, the mechanical integrity of the soft polymers was investigated under uniaxial tensile and uniaxial compressive stress using computational methods. The polymers were defined as 3D lattices following the dimension of existing wound dressings. Based on the simulation results of displacement and von Mises stress, the three polymers are mechanically safe to be used as wound dressing materials. © 2021 College of Engineering, Universiti Teknologi MARA (UiTM), Malaysia. All Rights Reserved. |
Computational analysis; Lattice; Soft polymer; Wound dressing |
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UiTM Press |
18235514 |
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Article |
Q3 |
216 |
18402 |
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