|
No records
|
|
570 |
Zahrah A., Muharam R., Luky Satria Marwali M., Ocktariyana, Deraya I.E., Asmarinah |
57205418186;57191492732;57225892448;57210235127;57216313121;15820317600; |
MRNA expression and DNA methylation level of the MMP-2 gene in peritoneal endometriosis |
2021 |
Journal of the Pakistan Medical Association |
71 |
2 |
|
S112 |
S115 |
|
|
https://www.scopus.com/inward/record.uri?eid=2-s2.0-85103683243&partnerID=40&md5=337ed161f28b3917b291ce8b733e951a |
Master Program of Biomedical Science, Faculty of Medicine Universitas Indonesia, Jakarta, Indonesia; Department of Obstetric and Ginecology, Faculty of Medicine Universitas Indonesia, Jakarta, Indonesia; Department of Obstetric and Ginecology, Fatmawati Central General Hospital, Jakarta, Indonesia; Department Miwifery, Politeknik Kesehatan Palembang, Ministry of Health, Indonesia; Department of Medical Biology, Faculty of Medicine Universitas Indonesia, Jakarta, Indonesia |
Zahrah, A., Master Program of Biomedical Science, Faculty of Medicine Universitas Indonesia, Jakarta, Indonesia; Muharam, R., Department of Obstetric and Ginecology, Faculty of Medicine Universitas Indonesia, Jakarta, Indonesia; Luky Satria Marwali, M., Department of Obstetric and Ginecology, Fatmawati Central General Hospital, Jakarta, Indonesia; Ocktariyana, Department Miwifery, Politeknik Kesehatan Palembang, Ministry of Health, Indonesia; Deraya, I.E., Department of Medical Biology, Faculty of Medicine Universitas Indonesia, Jakarta, Indonesia; Asmarinah, Master Program of Biomedical Science, Faculty of Medicine Universitas Indonesia, Jakarta, Indonesia |
Objective: Endometriosis is a multifactorial disease that affects 10% of women of childbearing age. Its development is known to be related to the MMP-2 gene. Specifically, the expression of MMP-2 is increase in endometriosis. The aim of this study was to evaluate the correlation between mRNA expression and DNA methylation levels of the MMP-2 gene in peritoneal endometriosis. Methods: This study used a cross-sectional design. The samples included peritoneal endometriosis tissue from women with endometriosis and normal endometrial tissue from women without endometriosis. Twenty samples of each type were taken, and the women were 20-45 years of age. Peritoneal endometriosis tissue was acquired using the laparoscopic technique, while normal endometrial tissue was taken with the microcuretase technique. The mRNA expression of the MMP-2 gene was analysed with qRT-PCR, and the level of DNA methylation of the MMP-2 gene was analysed with a methylation-specific PCR method. Results: The mRNA expression of MMP-2 gene in peritoneal endometriosis tissue was increased, and there were significant differences between peritoneal endometriosis tissue and normal endometrial tissue. The MMP-2 gene was hypermethylated, but there was no significant difference (p = 0.596) between peritoneal endometriosis tissue and endometrial tissue in terms of methylation. This study did not show a significant correlation between mRNA expression and DNA methylation levels of the MMP-2 gene (p = 0.769, r = 0.070). Conclusion: The increase in MMP-2 gene expression in peritoneal endometriosis tissue is likely not only due to hypermethylation; there are other factors that might play a role. © 2021 Pakistan Medical Association. All rights reserved. |
cytoskeleton. (JPMA 71: S-112 [Suppl. 2]; 2021); DNA methylation; endometriosis; MMP-2 |
gelatinase A; messenger RNA; cross-sectional study; DNA methylation; endometriosis; endometrium; female; genetics; human; metabolism; Cross-Sectional Studies; DNA Methylation; Endometriosis; Endometrium; Female; Humans; Matrix Metalloproteinase 2; RNA, Messenger |
Pakistan Medical Association |
00309982 |
|
33785954 |
Conference Paper |
Q4 |
242 |
17081 |
|
|
|
571 |
Tjahjadi R., Yusra |
57222664622;57195939842; |
Coexisting systemic lupus erythematosus and suspected hyperimmunoglobulin e syndrome: A case report |
2021 |
Journal of the Pakistan Medical Association |
71 |
2 |
|
S140 |
S142 |
|
|
https://www.scopus.com/inward/record.uri?eid=2-s2.0-85103682942&partnerID=40&md5=979daa2d43ac0c56ba2e276b8df67521 |
Department of Clinical Pathology, Universitas Indonesia, Cipto Mangunkusumo National General Hospital, Jakarta, Indonesia |
Tjahjadi, R., Department of Clinical Pathology, Universitas Indonesia, Cipto Mangunkusumo National General Hospital, Jakarta, Indonesia; Yusra, Department of Clinical Pathology, Universitas Indonesia, Cipto Mangunkusumo National General Hospital, Jakarta, Indonesia |
Hyperimmunoglobulin E syndrome (HIES) is a rare multisystem syndrome that affects musculoskeletal system, connective tissue, and immune system. Immune dysregulation in hyperimmunoglobulin E syndrome often accompanied by autoimmune diseases, such as systemic lupus erythematosus. While the role of IgG autoantibody is well known in the pathogenesis of systemic lupus erythematosus, other subtypes of autoantibodies, IgE in particular, are now known to be involved in autoimmune process. A female with known elevated IgE was diagnosed with adult onset HIES. Atypical chest pain and otherwise normal cardiac imaging studies prompted her for further lab testings. Positive antinuclear antibody immunofluorescence test and elevated anti ds-DNA led to SLE diagnosis. Lack of characteristic clinical manifestations complicates establishing HIES while showing the extent to which IgE elevation could be related to SLE. © 2021 Pakistan Medical Association. All rights reserved. |
Hyperimmunoglobulin E syndrome; IgE; Systematic lupus erythematosus. |
autoantibody; adult; autoimmune disease; case report; complication; female; human; systemic lupus erythematosus; Adult; Autoantibodies; Autoimmune Diseases; Female; Humans; Lupus Erythematosus, Systemic |
Pakistan Medical Association |
00309982 |
|
33785959 |
Conference Paper |
Q4 |
242 |
17081 |
|
|
|
572 |
Runtu F.M.J.G., Ardhia S.H., Lokeswara A.W., Friska D. |
57204110436;57222662640;57200937543;57202805330; |
Shaping effective communication skills in first-year medical students through community diagnosis exercise |
2021 |
Journal of the Pakistan Medical Association |
71 |
2 |
|
S37 |
S41 |
|
1 |
https://www.scopus.com/inward/record.uri?eid=2-s2.0-85103682708&partnerID=40&md5=53c2f59a400f54bb8e04b8a5a8b7140a |
Undergraduate Student, Faculty of Medicine, Universitas Indonesia, Indonesia; Department of Community Medicine, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia |
Runtu, F.M.J.G., Undergraduate Student, Faculty of Medicine, Universitas Indonesia, Indonesia; Ardhia, S.H., Undergraduate Student, Faculty of Medicine, Universitas Indonesia, Indonesia; Lokeswara, A.W., Undergraduate Student, Faculty of Medicine, Universitas Indonesia, Indonesia; Friska, D., Department of Community Medicine, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia |
Objective: The current study aimed to evaluate the impact of students' participation in this community diagnosis (CD) exercise on their competency development. Methods: The CD was performed by 235 first-year students through a home visit to obtain health data through questionnaire and physical examination; the data was analysed using the IBM® SPSS® version 24 statistical analysis software. The impact of CD participation on student skills development was evaluated using a cross sectional questionnaire-based survey using the Likert five-point scale to assess student attitudes. Results: CD exercise was performed by 235 first-year students by collecting data from 373 community residents. Subsequently, survey on effect of CD exercise on student competency responses were collected from 47 students (20%) of the 235 CD participants; the results showed that most agreed that CD enhanced their competence as physicians in all areas. The highest mean (SD) Likert scale score was recorded for the statement, 'CD enhanced effective communication' (4.47 ±} 0.747). A total of 44 (93.6%) respondents supported the continuation of CD, claiming that the activity is a forum through which students can practice interacting with patients. Conclusion: The survey found that effective communication is the skill most established by involvement in CD, and the activity provides a good base for students' self-development as professional physicians. © 2021 Pakistan Medical Association. All rights reserved. |
(JPMA 71: S-37 [Suppl. 2]; 2021); Communication; Community; Diagnosis; Medical education |
adult; communication skill; conference paper; controlled study; exercise; female; health data; home visit; human; Likert scale; major clinical study; male; medical education; medical student; physical examination; questionnaire; resident; software; student attitude; clinical competence; interpersonal communication; Clinical Competence; Communication; Humans; Physical Examination; Students, Medical; Surveys and Questionnaires |
Pakistan Medical Association |
00309982 |
|
33785939 |
Conference Paper |
Q4 |
242 |
17081 |
|
|
|
573 |
Ambarsari C.G., Tambunan T., Pardede S.O., Rahman FarhanH.F., Kadaristiana A. |
57211850895;55338756200;57210394278;57215612971;57214116079; |
Role of dipstick albuminuria in progression of paediatric chronic kidney disease |
2021 |
Journal of the Pakistan Medical Association |
71 |
2 |
|
S103 |
S106 |
|
1 |
https://www.scopus.com/inward/record.uri?eid=2-s2.0-85103682550&partnerID=40&md5=586bf5c6a6dfb2305e50086dc7cad5ed |
Department of Child Health, Cipto Mangunkusumo Hospital, Universitas Indonesia, Jakarta, Indonesia |
Ambarsari, C.G., Department of Child Health, Cipto Mangunkusumo Hospital, Universitas Indonesia, Jakarta, Indonesia; Tambunan, T., Department of Child Health, Cipto Mangunkusumo Hospital, Universitas Indonesia, Jakarta, Indonesia; Pardede, S.O., Department of Child Health, Cipto Mangunkusumo Hospital, Universitas Indonesia, Jakarta, Indonesia; Rahman, FarhanH.F., Department of Child Health, Cipto Mangunkusumo Hospital, Universitas Indonesia, Jakarta, Indonesia; Kadaristiana, A., Department of Child Health, Cipto Mangunkusumo Hospital, Universitas Indonesia, Jakarta, Indonesia |
Objective: Renal function of patients with chronic kidney disease (CKD) is typically evaluated by detecting proteinuria because it is a major predictor of CKD progression. In paediatric patients with CKD, urine albumin-Tocreatinine ratio (ACR) is used to detect CKD progression, which is similar to urine protein-To-creatinine ratio (PCR). However, facilities for evaluation of urine ACR and urine PCR may not be widely available. To date, this is the first study that investigated the predictive value of baseline dipstick albuminuria for 1-year and 3-year CKD progression in Indonesian children. We assessed the association between baseline level of dipstick albuminuria and CKD progression in paediatric patients. Methods: This retrospective cohort study was conducted at the Cipto Mangunkusumo Hospital (CMH) involving 43 children with CKD between 2016 and 2019. The patients were followed up for 1 year and 3 years after enrolment. Risk ratios (RR) for 1-year and 3-year CKD progression were calculated using Fisher's exact test. Results: The RR for 1-year CKD progression in children with baseline dipstick albuminuria 2+ was 2.16 (95% CI: 1.13-4.14, p = 0.02), and the corresponding RR for 3-year CKD progression in these children was 1.70 (95% CI: 0.73-3.97, p=0.21). Conclusion: Dipstick albuminuria was not associated with 1-year and 3-year CKD progression in children. © 2021 Pakistan Medical Association. All rights reserved. |
2021); albuminuria; chronic; chronic renal insufficiency; Kidney failure; proteinuria. (JPMA 71: S-103 [Suppl. 2] |
creatinine; albuminuria; child; chronic kidney failure; disease exacerbation; glomerulus filtration rate; human; Indonesia; retrospective study; Albuminuria; Child; Creatinine; Disease Progression; Glomerular Filtration Rate; Humans; Indonesia; Renal Insufficiency, Chronic; Retrospective Studies |
Pakistan Medical Association |
00309982 |
|
33785952 |
Conference Paper |
Q4 |
242 |
17081 |
|
|
|
590 |
Ngoo K.S., Fadzli A.N., Amponin M.O.C.S.E., Cho S.Y., Chuang Y.-C., Horiguchi A., Karthikeyan V.S., Morshed M.S., Situmorang G.R., Tan T.C., Teoh J.Y.-C., Thaidumrong T., Ong T.-A. |
24577210000;56690508000;57221558858;55686246500;16416810000;21634678200;55320137500;57200423093;57190001213;57221554527;55337855700;44062024500;7102866871; |
COVID-19 pandemic impact on urology residencies in Asia - An observational study |
2021 |
Surgical Practice |
25 |
1 |
|
10 |
15 |
|
1 |
https://www.scopus.com/inward/record.uri?eid=2-s2.0-85099476598&doi=10.1111%2f1744-1633.12474&partnerID=40&md5=2f2654abe61580ca20505968f145337d |
Department of Surgery, Hospital Angkatan Tentera Tuanku Mizan, Kuala Lumpur, Malaysia; Urology Unit, Department of Surgery, University of Malaya Medical Center, Kuala Lumpur, Malaysia; Department of Surgery, Our Lady of Lourdes Hospital, Manila, Philippines; Department of Urology, Seoul National University Hospital, Seoul, South Korea; Department of Urology, Kaohsiung Chang Gung Memorial Hospital, Chang Gung University College of Medicine, Kaohsiung, Taiwan; Department of Urology, National Defense Medical College, Saitama, Japan; Men's Health and Urology, Sri Narayani Hospital and Research Centre, Vellore, India; Department of Urology, Dhaka Medical College Hospital, Dhaka, Bangladesh; Department of Urology, Cipto Mangunkusumo National Referral Hospital, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Urology C Department, Binh Dan Hospital, Ho Chi Minh City, Viet Nam; Department of Surgery, Faculty of Medicine, The Chinese University of Hong Kong, Shatin, Hong Kong; Division of Urology, Department of Surgery, Rajavithi Hospital, Bangkok, Thailand |
Ngoo, K.S., Department of Surgery, Hospital Angkatan Tentera Tuanku Mizan, Kuala Lumpur, Malaysia; Fadzli, A.N., Urology Unit, Department of Surgery, University of Malaya Medical Center, Kuala Lumpur, Malaysia; Amponin, M.O.C.S.E., Department of Surgery, Our Lady of Lourdes Hospital, Manila, Philippines; Cho, S.Y., Department of Urology, Seoul National University Hospital, Seoul, South Korea; Chuang, Y.-C., Department of Urology, Kaohsiung Chang Gung Memorial Hospital, Chang Gung University College of Medicine, Kaohsiung, Taiwan; Horiguchi, A., Department of Urology, National Defense Medical College, Saitama, Japan; Karthikeyan, V.S., Men's Health and Urology, Sri Narayani Hospital and Research Centre, Vellore, India; Morshed, M.S., Department of Urology, Dhaka Medical College Hospital, Dhaka, Bangladesh; Situmorang, G.R., Department of Urology, Cipto Mangunkusumo National Referral Hospital, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Tan, T.C., Urology C Department, Binh Dan Hospital, Ho Chi Minh City, Viet Nam; Teoh, J.Y.-C., Department of Surgery, Faculty of Medicine, The Chinese University of Hong Kong, Shatin, Hong Kong; Thaidumrong, T., Division of Urology, Department of Surgery, Rajavithi Hospital, Bangkok, Thailand; Ong, T.-A., Urology Unit, Department of Surgery, University of Malaya Medical Center, Kuala Lumpur, Malaysia |
Objective: The Coronavirus Disease 2019 (Covid-19) pandemic affected surgical training in many ways. This observational study was carried out to evaluate the impact of Covid-19 on urological residencies across Asia. Methodology: An open-ended survey questionnaire examining key areas in a urology training program was distributed to several urologists in Asia. The survey evaluated seven areas including the burden of Covid-19 disease, the need for re-deployment of residents, the impact on clinical work, the effect on research work for residents, the delivery of teaching to the residents, the impact on training and assessments, the effects on mental, personal health and social welfare of residents. Results: Reports from 11 Asian countries were analysed. There is stark variability in Covid-19 disease burden across Asia. Re-deployment occurred in selected Asian countries. Affected residents reported challenges obtaining personal protective equipment and training. Clinical workload and research were generally reduced except for countries reporting low volume Covid-19 cases. Residents teaching evolved from in-person to online platforms. Almost all residency program postponed their examinations. Mental health disturbance was more pronounced than personal health. Conclusions: The Covid-19 pandemic presented multiple obstacles to Asian urology residencies. The understanding of these challenges will assist program directors in developing mitigating measures. © 2020 College of Surgeons of Hong Kong |
Covid-19; pandemic; residency; urology |
anxiety; Article; coronavirus disease 2019; health; human; human experiment; learning; medical practice; medical student; mental health; multicenter study; observational study; propensity score; prostate biopsy; questionnaire; residency education; resuscitation; social status; social welfare; surgical training; teaching; teleconsultation; transrectal ultrasonography; urodynamics; uroflowmetry; urologist; urology; workload |
Blackwell Publishing Ltd |
17441625 |
|
|
Article |
Q4 |
109 |
28907 |
|
|
|
605 |
Unggul D.B., Abdullah S., Rachman A. |
57221961543;57204563168;57217184320; |
Laterality condition analysis on non-arteritic anterior ischemic optic neuropathy patient in one of the hospital in Jakarta with medical data mining |
2021 |
Journal of Physics: Conference Series |
1725 |
1 |
012096 |
|
|
|
|
https://www.scopus.com/inward/record.uri?eid=2-s2.0-85100803241&doi=10.1088%2f1742-6596%2f1725%2f1%2f012096&partnerID=40&md5=38c1992b179967890ac62988e4c116ad |
Department of Mathematics, Faculty of Mathematics and Natural Sciences (FMIPA), Universitas Indonesia, Depok, 16424, Indonesia; Division of Hematology and Medical Oncology, Department of Internal Medicine, Faculty of Medicine, Universitas Indonesia, Jakarta, 10430, Indonesia |
Unggul, D.B., Department of Mathematics, Faculty of Mathematics and Natural Sciences (FMIPA), Universitas Indonesia, Depok, 16424, Indonesia; Abdullah, S., Department of Mathematics, Faculty of Mathematics and Natural Sciences (FMIPA), Universitas Indonesia, Depok, 16424, Indonesia; Rachman, A., Division of Hematology and Medical Oncology, Department of Internal Medicine, Faculty of Medicine, Universitas Indonesia, Jakarta, 10430, Indonesia |
Non-arteritic Anterior Ischemic Optic Neuropathy (NAION) is a disease caused by blood shortages in the artery that supplies the optic disc. Risk factors for NAION are hypertension, obesity, diabetes, dislipidemia, smoking, hypercoagulable state, cardiovascular disease, and stroke. NAION can result from unilateral or bilateral conditions. This study will focus on the identification of important factors that could distinguish characteristics between unilateral and bilateral patients. Random forest method is applied to obtain factors that can consistently distinguish characteristic between each laterality condition. Decision trees and the logistic regression method are added to obtain the visualization of the role of each important factors in the form of classification tree and the risk comparison of patients for experiencing a certain laterality condition by using odds ratios. The important factors based on random forest model are onset, fasting blood glucose levels, high density lipoprotein levels, age, two-hour postprandial glucose levels, and low density lipoprotein levels. Based on the odds ratio, advancing age and high density lipoprotein levels will decrease the risk of patients experiencing bilateral condition; on the other hand, the risk of bilateral condition will increase if other important factors are also increased. © 2021 Journal of Physics: Conference Series. |
Decision tree; Laterality; Logistic regression; Random forest |
Blood; Decision trees; Glucose; Lipoproteins; Logistic regression; Medical computing; Random forests; Blood glucose level; Cardio-vascular disease; Classification trees; High density lipoprotein levels; Logistic regression method; Low density lipoproteins; Random forest methods; Random forest modeling; Data mining |
IOP Publishing Ltd |
17426588 |
|
|
Conference Paper |
Q4 |
210 |
18731 |
|
|
|
606 |
Hanifah N., Wiweko B., Bowolaksono A. |
57200075370;43061741400;57205093224; |
FSHR and LHR mRNA expression in granulosa cells of poor responder |
2021 |
Journal of Physics: Conference Series |
1725 |
1 |
012057 |
|
|
|
|
https://www.scopus.com/inward/record.uri?eid=2-s2.0-85100793552&doi=10.1088%2f1742-6596%2f1725%2f1%2f012057&partnerID=40&md5=498a20aef40d78ffcc6b9fa74da8dec6 |
Department of Biology, Faculty of Mathematics and Natural Sciences (FMIPA), Universitas Indonesia, Depok, 16424, Indonesia; Department of Obstetric and Gynecology, Faculty of Medicine, Universitas Indonesia, Depok, 16424, Indonesia |
Hanifah, N., Department of Biology, Faculty of Mathematics and Natural Sciences (FMIPA), Universitas Indonesia, Depok, 16424, Indonesia; Wiweko, B., Department of Obstetric and Gynecology, Faculty of Medicine, Universitas Indonesia, Depok, 16424, Indonesia; Bowolaksono, A., Department of Biology, Faculty of Mathematics and Natural Sciences (FMIPA), Universitas Indonesia, Depok, 16424, Indonesia |
In Vitro Fertilization (IVF) is one of the most commonly used procedures to help pregnancies in couples who have infertility problems. One of the problems of infertility is poor ovarian response and the woman who experiences it is known as poor responder. Poor responders do not have an adequate ovarian response to gonadotropin in ovarian stimulation. The success of fertilization in poor responders tends to be low due to low quantity and is generally followed by low oocyte quality. Gonadotropins consisting of FSH and LH, play a role in follicle development and ovulation. The follicle response in capturing gonadotropins depends on the exact bond between the hormone and its receptor (FSHR and LHR) in the granulosa cells surrounding the oocyte. The purpose of this research is to know the expression level of fshr and lhr mRNA in granulosa cells of poor responders through real-time PCR method which then tested statistically using t-test. Fourteen samples of each poor responders and normal women were used in this research. The results showed insignificant differences between expression level of fshr and lhr mRNA in granulosa cells of poor responders and normal women (p > 0.05). © 2021 Journal of Physics: Conference Series. |
FSHR; LHR; Poor ovarian response; Real-time PCR |
Cytology; Polymerase chain reaction; Expression levels; Follicle development; Granulosa cells; In-vitro; mRNA expression; Real-time PCR method; T-tests; Cells |
IOP Publishing Ltd |
17426588 |
|
|
Conference Paper |
Q4 |
210 |
18731 |
|
|
|
607 |
Lestari D.A., Abdullah S., Rachman A. |
56119337300;57204563168;57217184320; |
Identification of factors associated with hypothyroidism due to radiotherapy in patients with nasopharyngeal cancer (Case study of nasopharyngeal cancer in one of the hospitals in Jakarta) |
2021 |
Journal of Physics: Conference Series |
1725 |
1 |
012027 |
|
|
|
|
https://www.scopus.com/inward/record.uri?eid=2-s2.0-85100793360&doi=10.1088%2f1742-6596%2f1725%2f1%2f012027&partnerID=40&md5=eb87ed0fd4bc75637854a08478652d08 |
Department of Mathematics, Faculty of Mathematics and Natural Sciences (FMIPA), Universitas Indonesia, Depok, 16424, Indonesia; Division of Hematology and Medical Oncology, Department of Internal Medicine, Faculty of Medicine, Universitas Indonesia, Jakarta, 10430, Indonesia |
Lestari, D.A., Department of Mathematics, Faculty of Mathematics and Natural Sciences (FMIPA), Universitas Indonesia, Depok, 16424, Indonesia; Abdullah, S., Department of Mathematics, Faculty of Mathematics and Natural Sciences (FMIPA), Universitas Indonesia, Depok, 16424, Indonesia; Rachman, A., Division of Hematology and Medical Oncology, Department of Internal Medicine, Faculty of Medicine, Universitas Indonesia, Jakarta, 10430, Indonesia |
Nasopharyngeal cancer is an abnormal cell growth that develops around the nasopharynx. Treatment of nasopharyngeal cancer patients includes chemotherapy or radiotherapy. Both treatments have side effects in patients. In this study, we will focus on hypothyroidism as a side effect of radiotherapy in the treatment of patients with nasopharyngeal cancer. Hypothyroidism is a condition when the thyroid gland is unable to produce enough thyroid hormone. The main goal of this study is to identify the factors associated with hypothyroidism. To achieve this goal, classification tree and logistic regression methods will be used. Classification tree is used to obtain important variables in the classification of subject classes. Then, logistic regression is used to quantify the risk of variables that appear in the classification tree, hypothyroidism risk factors, and hypothyroidism marker factors. Based on the analysis, it was found that the factors associated in this study were variable symptom, physical sign, smoking habits, gender, age, BMI (Body Mass Index), TSH (Thyroid Stimulating Hormone) and fT4 (free thyroxine) hormones, and also all items on Zulewski score, except items delayed ankle reflex and slow movements. These factors associated tended to increase the risk of hypothyroidism, except for the fT4 hormone and BMI. © 2021 Journal of Physics: Conference Series. |
Classification tree; Hypothyroidism; Logistic regression; Marker factors; Risk factors |
Cell proliferation; Chemotherapy; Hormones; Logistic regression; Radiotherapy; Body mass index; Classification trees; Logistic regression method; Nasopharyngeal cancer; Risk factors; Thyroid glands; Thyroid hormones; Thyroid stimulating hormones; Diseases |
IOP Publishing Ltd |
17426588 |
|
|
Conference Paper |
Q4 |
210 |
18731 |
|
|
|
608 |
Lukman P.A., Abdullah S., Rachman A. |
57221968648;57204563168;57217184320; |
Bayesian logistic regression and its application for hypothyroid prediction in post-radiation nasopharyngeal cancer patients |
2021 |
Journal of Physics: Conference Series |
1725 |
1 |
012010 |
|
|
|
|
https://www.scopus.com/inward/record.uri?eid=2-s2.0-85100754485&doi=10.1088%2f1742-6596%2f1725%2f1%2f012010&partnerID=40&md5=902f22d97f61ad13843e9bbe6a66f42e |
Department of Mathematics, Faculty of Mathematics and Natural Sciences (FMIPA), Universitas Indonesia, Depok, 16424, Indonesia; Department of Medical Education, Faculty of Medicine, Universitas Indonesia, Depok, 16424, Indonesia |
Lukman, P.A., Department of Mathematics, Faculty of Mathematics and Natural Sciences (FMIPA), Universitas Indonesia, Depok, 16424, Indonesia; Abdullah, S., Department of Mathematics, Faculty of Mathematics and Natural Sciences (FMIPA), Universitas Indonesia, Depok, 16424, Indonesia; Rachman, A., Department of Medical Education, Faculty of Medicine, Universitas Indonesia, Depok, 16424, Indonesia |
Logistic regression models are commonly used to model response variables in the form of categorical variables with several predictor variables. The contribution of the predictor variable to the response variable is expressed through a regression coefficient (β). Therefore, it is necessary to estimate β. This study discusses the estimation of β using the Bayesian method. Bayesian approach utilizes a combination of information from sample data and prior information about the characteristics of the parameters of interest, resulting in the updated information, namely the posterior. Bayesian method thus can overcome the problem if the quality of the sample data does not support observation. Bayesian logistic regression method will be used in analyzing post-radiation nasopharyngeal cancer (NPC) patient data, using measurement on Zulewski's score components. Markov Chain Monte Carlo with Gibbs Sampling were used to obtain the sample from posterior distribution. Convergent estimates were obtained, and the result showed that Zulewski's component scores only were not enough to explain the hypothyroidism in NPC. Additional information is required in order to explain the incidence of hypothyroidism in NPC. © 2021 Journal of Physics: Conference Series. |
Bayesian logistic regression; Gibbs sampling; Logistic regression; Markov chain monte carlo; Nasopharyngeal cancer |
Bayesian networks; Diseases; Hospital data processing; Markov chains; Radiotherapy; Categorical variables; Logistic regression method; Logistic regression models; Markov Chain Monte-Carlo; Nasopharyngeal cancer; Posterior distributions; Regression coefficient; Updated informations; Logistic regression |
IOP Publishing Ltd |
17426588 |
|
|
Conference Paper |
Q4 |
210 |
18731 |
|
|
|
609 |
Amelia V., Siswantining T., Kamelia T. |
57221954910;57193446800;35603752000; |
Prediction model of exacerbations in patients with Chronic Obstructive Pulmonary Disease (COPD) at RSCM |
2021 |
Journal of Physics: Conference Series |
1725 |
1 |
012011 |
|
|
|
|
https://www.scopus.com/inward/record.uri?eid=2-s2.0-85100735594&doi=10.1088%2f1742-6596%2f1725%2f1%2f012011&partnerID=40&md5=3f0c08db1ff574eac108d1a10d8c68a9 |
Department of Mathematics, Faculty of Mathematics and Natural Sciences (FMIPA), Universitas Indonesia, Depok, 16424, Indonesia; Division of Pulmonology, Department of Internal Medicine, Faculty of Medicine, Universitas Indonesia, Jakarta, 10430, Indonesia |
Amelia, V., Department of Mathematics, Faculty of Mathematics and Natural Sciences (FMIPA), Universitas Indonesia, Depok, 16424, Indonesia; Siswantining, T., Department of Mathematics, Faculty of Mathematics and Natural Sciences (FMIPA), Universitas Indonesia, Depok, 16424, Indonesia; Kamelia, T., Division of Pulmonology, Department of Internal Medicine, Faculty of Medicine, Universitas Indonesia, Jakarta, 10430, Indonesia |
Chronic Obstructive Pulmonary Disease (COPD) is a worldwide health problem. COPD has a tendency for exacerbations. Exacerbations are worsening of acute respiratory symptoms resulting in additional therapy. Exacerbations in COPD increase the risk of death. The objective of this study is to determine the prediction model of exacerbations in patients with COPD based on factors affecting exacerbations in patients with COPD at RSCM (Rumah Sakit Cipto Mangunkusumo). The data used in this study is secondary data from the medical records of patients with COPD in RSCM. The sample was chosen using purposive sampling technique. The samples in this study are 107 patients with COPD. The method used is binary logistic regression analysis. The results of this study indicate that the factors that significantly influence the exacerbations of COPD are breathlessness, history of ICS use, and history of antibiotics use. Appropriate logistic regression model has been obtained. The result indicates that patients with COPD who have breathlessness, have history of ICS use, and have history of antibiotics use are more at risk of exacerbations than those who don't. Accuracy test has been conducted with classification table at cut point 0.5. The prediction model has an accuracy rate of 74.77 %. © 2021 Journal of Physics: Conference Series. |
COPD; Exacerbations; Logistic regression |
Antibiotics; Forecasting; Logistic regression; Predictive analytics; Binary logistic regression; Chronic obstructive pulmonary disease; Logistic Regression modeling; Medical record; Prediction model; Respiratory symptoms; Sampling technique; Secondary datum; Pulmonary diseases |
IOP Publishing Ltd |
17426588 |
|
|
Conference Paper |
Q4 |
210 |
18731 |
|
|
