|
No records
|
|
575 |
Fuady A., Houweling T.A.J., Richardus J.H. |
37085331400;10639726000;7003977198; |
Perspective piece COVID-19 and tuberculosis-related catastrophic costs |
2021 |
American Journal of Tropical Medicine and Hygiene |
104 |
2 |
|
436 |
440 |
|
4 |
https://www.scopus.com/inward/record.uri?eid=2-s2.0-85101400221&doi=10.4269%2fajtmh.20-1125&partnerID=40&md5=a3c370677fb6cad8407b4d92b3768798 |
Department of Public Health, Erasmus MC, University Medical Center Rotterdam, Rotterdam, Netherlands; Department of Community Medicine, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia |
Fuady, A., Department of Public Health, Erasmus MC, University Medical Center Rotterdam, Rotterdam, Netherlands, Department of Community Medicine, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Houweling, T.A.J., Department of Public Health, Erasmus MC, University Medical Center Rotterdam, Rotterdam, Netherlands; Richardus, J.H., Department of Public Health, Erasmus MC, University Medical Center Rotterdam, Rotterdam, Netherlands |
The COVID-19 pandemic has created an unprecedented health crisis and a substantial socioeconomic impact. It also affects tuberculosis (TB) control severely worldwide. Interruptions of many TB control programs because of the COVID-19 pandemic could result in significant setbacks. One of the targets that can be affected is the WHO's End TB Strategy goal to eliminate catastrophic costs of TB-affected households by 2030. Disruptions to TB programs and healthcare services due to COVID-19 could potentially prolong diagnostic delays and worsen TB treatment adherence and outcomes. The economic recession caused by the pandemic could significantly impact household financial capacity because of the reduction of income and the rise in unemployment rates. All of these factors increase the risk of TB incidence and the gravity of economic impact on TB-affected households, and hamper efforts to eliminate catastrophic costs and control TB. Therefore, efforts to eliminate the incidence of TB-affected households facing catastrophic costs will be very challenging. Because financial constraint plays a significant role in TB control, the improvement of health and social protection systems is critical. Even before the pandemic, many TB-high-burden countries (HBCs) lacked robust health and social protection systems. These challenges highlight the substantial need for a more robust engagement of patients and civil society organizations and international support in addressing the consequences of COVID-19 on the control of TB. © 2021 by The American Society of Tropical Medicine and Hygiene. |
|
tuberculostatic agent; clinical outcome; coronavirus disease 2019; delayed diagnosis; disaster; disease burden; disease control; economic recession; financial management; health care cost; health program; health service; household; human; incidence; income; infection control; infection risk; organization; pandemic; patient compliance; Review; social aspect; social protection system; socioeconomics; tuberculosis; unemployment; World Health Organization; economics; family size; health care cost; tuberculosis; COVID-19; Family Characteristics; Health Care Costs; Humans; Incidence; Income; SARS-CoV-2; Tuberculosis |
American Society of Tropical Medicine and Hygiene |
00029637 |
|
33269683 |
Review |
Q1 |
1015 |
4298 |
|
|
|
577 |
Hayuningtyas A., Dewi Y.A., Octavia L., Pulungan A., Agustina R. |
57221416876;57221416331;57205693397;57192905981;57214141404; |
Dietary quality score is positively associated with serum adiponectin level in Indonesian preschool-Age children living in the urban area of Jakarta |
2021 |
PLoS ONE |
16 |
2 February 2021 |
e0246234 |
|
|
|
|
https://www.scopus.com/inward/record.uri?eid=2-s2.0-85100556583&doi=10.1371%2fjournal.pone.0246234&partnerID=40&md5=96542590163d73f573030ac70b15220c |
Department of Nutrition, Faculty of Medicine, Universitas Indonesia Dr. Cipto Mangunkusumo General Hospital, Jakarta, Indonesia; Department of Child Health, Faculty of Medicine, Universitas Indonesia Dr. Cipto Mangunkusumo General Hospital, Jakarta, Indonesia; Human Nutrition Research Centre, Indonesia Medical Education and Research Institute Indonesia, Faculty of Medicine, Jakarta, Indonesia |
Hayuningtyas, A., Department of Nutrition, Faculty of Medicine, Universitas Indonesia Dr. Cipto Mangunkusumo General Hospital, Jakarta, Indonesia; Dewi, Y.A., Department of Nutrition, Faculty of Medicine, Universitas Indonesia Dr. Cipto Mangunkusumo General Hospital, Jakarta, Indonesia; Octavia, L., Department of Nutrition, Faculty of Medicine, Universitas Indonesia Dr. Cipto Mangunkusumo General Hospital, Jakarta, Indonesia; Pulungan, A., Department of Child Health, Faculty of Medicine, Universitas Indonesia Dr. Cipto Mangunkusumo General Hospital, Jakarta, Indonesia; Agustina, R., Department of Nutrition, Faculty of Medicine, Universitas Indonesia Dr. Cipto Mangunkusumo General Hospital, Jakarta, Indonesia, Human Nutrition Research Centre, Indonesia Medical Education and Research Institute Indonesia, Faculty of Medicine, Jakarta, Indonesia |
An unhealthy diet during childhood directly impacts the risk of developing noncommunicable diseases (NCDs) later on in life. However, well-documented information on this issue is lacking. We investigated the dietary quality of young Indonesian children and assessed the relationship to serum adiponectin levels as an early marker of NCDs. Eighty-five (44 girls and 41 boys) Indonesian preschool-Age children in East Jakarta were included in this study. Dietary intake data were gathered by collecting repeated 24-hour recalls for one weekday and one day during the weekend, which were then further converted into participants Healthy Eating Index (HEI) 2015 scores. Meanwhile, an enzyme-linked immunosorbent assay was performed to determine the serum adiponectin level. A multiple regression analysis was performed to assess the association between the HEI 2015 score and serum adiponectin, adjusting for potential confounders. The mean HEI 2015 score was 33.2 ± 8.3 points, which was far below the recommended score of ≤80 points, while the mean serum adiponectin was 10.3 ± 4.1 μg/mL. Multiple linear regression testing showed that a one-point increase in the HEI 2015 score was significantly associated with an increase in the serum adiponectin level by 0.115 μg/mL after adjusting for exclusive breastfeeding history (β = 0.115; 95% CI = 0.010 0.221; p = 0.032). In conclusion, better adherence of young children to a healthy diet has a positive association with their adiponectin level. This result suggests that strengthening children s dietary quality from an early age by involving all parties in the children s environment (e.g., parents, teachers at school, policymakers) may help to reduce the risk of NCDs later on in childhood and during adult life. © 2021 Public Library of Science. All rights reserved. |
|
adiponectin; ADIPOQ protein, human; blood; clinical trial; cross-sectional study; female; human; Indonesia; male; preschool child; statistical model; urban population; Adiponectin; Child, Preschool; Cross-Sectional Studies; Diet, Healthy; Female; Humans; Indonesia; Linear Models; Male; Urban Population |
Public Library of Science |
19326203 |
|
33539478 |
Article |
Q1 |
990 |
4434 |
|
|
|
578 |
Arguni E., Karyanti M.R., Satari H.I., Hadinegoro S.R. |
8520598700;56290680800;57226214366;56893685800; |
Diphtheria outbreak in Jakarta and Tangerang, Indonesia: Epidemiological and clinical predictor factors for death |
2021 |
PLoS ONE |
16 |
2 February |
e0246301 |
|
|
|
3 |
https://www.scopus.com/inward/record.uri?eid=2-s2.0-85100508974&doi=10.1371%2fjournal.pone.0246301&partnerID=40&md5=d5c31533e8d632bb7459927c7da0cce2 |
Department of Child Health, Faculty of Medicine Public Health and Nursing, Universitas Gadjah Mada, Yogyakarta, Indonesia; Department of Pediatric, Faculty of Medicine, University of Indonesia, Jakarta, Indonesia |
Arguni, E., Department of Child Health, Faculty of Medicine Public Health and Nursing, Universitas Gadjah Mada, Yogyakarta, Indonesia; Karyanti, M.R., Department of Pediatric, Faculty of Medicine, University of Indonesia, Jakarta, Indonesia; Satari, H.I., Department of Pediatric, Faculty of Medicine, University of Indonesia, Jakarta, Indonesia; Hadinegoro, S.R., Department of Pediatric, Faculty of Medicine, University of Indonesia, Jakarta, Indonesia |
Background In 2017, a diphtheria outbreak occurred in several provinces in Indonesia. The aim of this study was to identify predictors of mortality outcome of pediatric patients with clinical diphtheria. Methods A retrospective cohort study was conducted using patient medical records at five referral hospitals in the Province of Jakarta and one in Tangerang District, Banten Province during January 2017 to 31 August 2018. All children in the age group of 1-18 years old discharged with diagnosis of clinical diphtheria formed the study group. All anonymized patient data were evaluated for demographic issues, clinical features, immunization status, complication, laboratory profiles and outcome. Results A total of 283 patients with clinical diphtheria were included in the study group with case fatality rate of 3.5%. All mortal patients had the complication of myocarditis. Regression analyses revealed factors for predicting mortality. Incomplete primary diphtheria toxoid immunization, stridor, bull neck, leukocytosis ≥15 ×109 cells/L and thrombocytopenia ≤150 x109 cells/L in each combination for 2 predictors modeling were correlated with death. Conclusions We report key predictors of mortality in pediatric patients with clinical diphtheria. The presence of these features when admitted to the hospital must be taken into account, because they can lead to fatal outcome. © 2021 Arguni et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. |
|
adolescent; child; cohort analysis; complication; diphtheria; epidemic; female; hospitalization; human; immunization; Indonesia; infant; male; medical record; mortality; myocarditis; preschool child; regression analysis; retrospective study; vaccination; Adolescent; Child; Child, Preschool; Cohort Studies; Diphtheria; Disease Outbreaks; Female; Hospitalization; Humans; Immunization; Indonesia; Infant; Male; Medical Records; Myocarditis; Regression Analysis; Retrospective Studies; Vaccination |
Public Library of Science |
19326203 |
|
33539453 |
Article |
Q1 |
990 |
4434 |
|
|
|
579 |
Lee C.-C., Kwa A.L.H., Apisarnthanarak A., Feng J.-Y., Gluck E.H., Ito A., Karuniawati A., Periyasamy P., Pratumvinit B., Sharma J., Solante R., Swaminathan S., Tyagi N., Vu D.M., Zirpe K., Schuetz P. |
57216571107;57277379200;6603905554;24168534700;7003341685;37007598100;54886816200;57218573063;35722893000;12545686500;8728553100;56354453600;56471440500;57214066572;56521747700;35235208800; |
Erratum: Procalcitonin (PCT)guided antibiotic stewardship in Asia-Pacific countries: Adaptation based on an expert consensus meeting. (Clin Chem Lab Med (2020) 58:12 (1983–91) Doi:10.1515/cclm-2019-1122) |
2021 |
Clinical Chemistry and Laboratory Medicine |
59 |
3 |
|
631 |
632 |
|
|
https://www.scopus.com/inward/record.uri?eid=2-s2.0-85100458517&doi=10.1515%2fcclm-2020-1724&partnerID=40&md5=b517d7656483da02741274bbd916bf57 |
Singapore General Hospital, Singapore, Singapore; Emerging Infectious Diseases Program, Duke-National University of Singapore Medical School, Singapore, Singapore; Division of Infectious Diseases, Thammasart University Hospital, Bangkok, Thailand; Department of Chest Medicine, Taipei Veterans General Hospital, Taipei, Taiwan; Critical Care Services, Swedish Covenant Hospital, Chicago, IL, United States; Department of Respiratory Medicine, Ohara Healthcare Foundation, Kurashiki Central Hospital, Okayama, Japan; Department of Microbiology, Faculty of Medicine, Universitas Indonesia and Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Infectious Disease Unit, PPUKM (HCTM), Hospital Canselor Tuanku Muhriz UKM (HCTM), Universiti Kebangsaan Malaysia Medical Centre (UKMMC), Kuala Lumpur, Malaysia; Department of Clinical Pathology, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand; Artemis Hospital Critical Care Medicine, Gurgaon, India; Adult Infectious Diseases and Tropical Medicine, San Lazaro Hospital, Manila, Philippines; Infectious Diseases, Gleneagles Global Hospitals, Chennai and Bengaluru, India; Institute of Critical Care and Emergency Medicine, Sir Ganga Ram Hospital, Delhi, India; Critical Care Department, National Hospital of Tropical Diseases, Hanoi, Viet Nam; Department of Neuro Critical Care, Ruby Hall Clinic, Grant Medical Foundation, Pune, India; Department of Internal Medicine, Kantonsspital Aarau, Aarau, Switzerland; University of Basel, Basel, Switzerland |
Lee, C.-C., Singapore General Hospital, Singapore, Singapore; Kwa, A.L.H., Emerging Infectious Diseases Program, Duke-National University of Singapore Medical School, Singapore, Singapore, Division of Infectious Diseases, Thammasart University Hospital, Bangkok, Thailand; Apisarnthanarak, A., Department of Chest Medicine, Taipei Veterans General Hospital, Taipei, Taiwan; Feng, J.-Y., Critical Care Services, Swedish Covenant Hospital, Chicago, IL, United States; Gluck, E.H., Department of Respiratory Medicine, Ohara Healthcare Foundation, Kurashiki Central Hospital, Okayama, Japan; Ito, A., Department of Respiratory Medicine, Ohara Healthcare Foundation, Kurashiki Central Hospital, Okayama, Japan; Karuniawati, A., Department of Microbiology, Faculty of Medicine, Universitas Indonesia and Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Periyasamy, P., Infectious Disease Unit, PPUKM (HCTM), Hospital Canselor Tuanku Muhriz UKM (HCTM), Universiti Kebangsaan Malaysia Medical Centre (UKMMC), Kuala Lumpur, Malaysia; Pratumvinit, B., Department of Clinical Pathology, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand; Sharma, J., Artemis Hospital Critical Care Medicine, Gurgaon, India; Solante, R., Adult Infectious Diseases and Tropical Medicine, San Lazaro Hospital, Manila, Philippines; Swaminathan, S., Infectious Diseases, Gleneagles Global Hospitals, Chennai and Bengaluru, India; Tyagi, N., Institute of Critical Care and Emergency Medicine, Sir Ganga Ram Hospital, Delhi, India; Vu, D.M., Critical Care Department, National Hospital of Tropical Diseases, Hanoi, Viet Nam; Zirpe, K., Department of Neuro Critical Care, Ruby Hall Clinic, Grant Medical Foundation, Pune, India; Schuetz, P., Department of Internal Medicine, Kantonsspital Aarau, Aarau, Switzerland, University of Basel, Basel, Switzerland |
There is typo in Figure 1 and Figure 2 of this article. Instead of “… repeated testing or monitoring for discontinuation …” it should read “… repeated testing for monitoring and discontinuation …” (see corrected Figures). © 2021 De Gruyter. All rights reserved. |
|
erratum |
De Gruyter Open Ltd |
14346621 |
|
33554531 |
Erratum |
Q1 |
977 |
4522 |
|
|
|
603 |
Clarissa A., Sutandi N., Fath A.A. |
57201653912;57201654034;57257442900; |
Stem-Cell Therapy Following High-Dose Chemotherapy in Advanced Retinoblastoma: A Systematic Review |
2021 |
Asia-Pacific journal of ophthalmology (Philadelphia, Pa.) |
10 |
4 |
|
397 |
407 |
|
|
https://www.scopus.com/inward/record.uri?eid=2-s2.0-85114846321&doi=10.1097%2fAPO.0000000000000372&partnerID=40&md5=bd9b021766dfa6bd6c9f108c62bd4c7c |
Faculty of Medicine, Universitas IndonesiaJakarta, Indonesia |
Clarissa, A., Faculty of Medicine, Universitas IndonesiaJakarta, Indonesia; Sutandi, N.; Fath, A.A. |
PURPOSE: To analyze the risk and benefit of high-dose chemotherapy followed by stem cell transplantation (HDCT-SCT) treatment in patients with advanced retinoblastoma. DESIGN: Systematic review. METHODS: A comprehensive literature search from 4 online databases, including PubMed, Scopus, EBSCO, and Cochrane was done for original studies evaluating the use of HDCT followed by SCT in the treatment of patients with advanced retinoblastoma. The last search was performed on April 15, 2020. RESULTS: A total of 35 studies consisting of 160 patients were considered suitable for inclusion. After HDCT-SCT treatment, 108/160 (67.5%) patients were alive with no evidence of disease at the last follow-up. The incidence of secondary malignancy in our data was also relatively low, which was 16/160 (10%) patients. The side effects were mainly hematological and gastrointestinal toxicities. The prognosis for metastatic cases especially the one to the central nervous system (CNS) remains poor, as shown in our data that 22 of 44 (50%) patients died due to the evidence of disease, and 12 of 44 (27%) patients acquired CNS relapse and died. CONCLUSIONS: HDCT-SCT is a promising treatment option in patients with advanced retinoblastoma. The use of HDCT-SCT in CNS metastases needs to be carefully considered, possibly by adding thiotepa or topotecan to improve tumor control. Further randomized clinical trials are needed to draw firm conclusion regarding its safety and efficacy. Copyright © 2021 Asia-Pacific Academy of Ophthalmology. Published by Wolters Kluwer Health, Inc. on behalf of the Asia-Pacific Academy of Ophthalmology. |
|
antineoplastic agent; human; multimodality cancer therapy; retina tumor; retinoblastoma; stem cell transplantation; tumor recurrence; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Therapy; Humans; Neoplasm Recurrence, Local; Retinal Neoplasms; Retinoblastoma; Stem Cell Transplantation |
NLM (Medline) |
21620989 |
|
33481395 |
Article |
#N/A |
#N/A |
#N/A |
|
|
|
620 |
Setyawan H.B., Yulianto R., Santoso W.D., Suryandari N. |
57221951849;57214720503;6506080422;57221947574; |
Fern plant (Pteris vittata) as a phytoremediator of arsenic heavy metal and its effect to the growth and quality of Kale (Ipomea reptans Poir) |
2021 |
IOP Conference Series: Earth and Environmental Science |
637 |
1 |
012066 |
|
|
|
|
https://www.scopus.com/inward/record.uri?eid=2-s2.0-85100756752&doi=10.1088%2f1755-1315%2f637%2f1%2f012066&partnerID=40&md5=39224fc2c888c20765d655154da66bc5 |
Animal Husbandry Department, Faculty of Agriculture, University of Jember, Indonesia; Internal Medicine Department, Faculty of Medicine, University of Indonesia, Indonesia; Agrotechnology Departement, Faculty of Agriculture, University of Jember, Indonesia |
Setyawan, H.B., Animal Husbandry Department, Faculty of Agriculture, University of Jember, Indonesia; Yulianto, R., Animal Husbandry Department, Faculty of Agriculture, University of Jember, Indonesia; Santoso, W.D., Internal Medicine Department, Faculty of Medicine, University of Indonesia, Indonesia; Suryandari, N., Agrotechnology Departement, Faculty of Agriculture, University of Jember, Indonesia |
Kale (Ipomea reptans Poir) has high nutrition such as vitamin A, B and C as well as various minerals especially iron. Quality of animal feed must be clean from diseases and heavy metal contamination such as Arsenic. Arsenic in the soil can be reduced naturally using phytoremediator plants, one of which is Pteris vittata. The experiment was conducted at the Antirogo Green House, Sumbersari Distric, Jember Regency. Arsenic metal analysis was conducted in BARISTAND, Surabaya and BALITTANAH, Bogor on June 2019 to January 2020. The experimental design used Factorial Complete Random Design consist of 2 factors. The first factor consists of 4 levels of heavy metal arsenic treatment on the fern plant growth media, namely was 0 ppm (D1), 5 ppm (D2), 10 ppm (D3) and 15 ppm (D4). The second factor consists of 2 levels of treatment time of fern: 1 month (P1) and 2 weeks (P2). Each of treatment repeated 4 times. The results showed that the interaction between planting time of fern and arsenic dosage showed no significant effect. The absorption power of ferns reaches 0.27 ppm to 4.589 ppm higher compared to the scale absorptions reaching 0,006 ppm to 0.155 ppm. © 2021 Institute of Physics Publishing. All rights reserved. |
|
Agriculture; Arsenic; Heavy metals; Metal analysis; Sustainable development; 2-factors; Absorption power; Animal feed; Heavy metal contamination; Plant growth; Pteris vittata; Treatment time; Vitamin A; Chemical contamination |
IOP Publishing Ltd |
17551307 |
|
|
Conference Paper |
- |
179 |
20770 |
|
|
|
621 |
George P.M.A., Abdullah S., Rachman A. |
57221954733;57204563168;57217184320; |
Analysis of Hypothyroidism Development in Post-Radiotherapy Nasopharyngeal Cancer Patients using Survival Trees |
2021 |
Journal of Physics: Conference Series |
1722 |
1 |
012095 |
|
|
|
|
https://www.scopus.com/inward/record.uri?eid=2-s2.0-85100712595&doi=10.1088%2f1742-6596%2f1722%2f1%2f012095&partnerID=40&md5=b152a0810c9274777e385793bf11e707 |
Department of Mathematics, Universitas Indonesia, Kampus Baru UI, Depok, 16424, Indonesia; Department of Oncology, Faculty of Medicine, Universitas Indonesia, Depok, 16424, Indonesia |
George, P.M.A., Department of Mathematics, Universitas Indonesia, Kampus Baru UI, Depok, 16424, Indonesia; Abdullah, S., Department of Mathematics, Universitas Indonesia, Kampus Baru UI, Depok, 16424, Indonesia; Rachman, A., Department of Oncology, Faculty of Medicine, Universitas Indonesia, Depok, 16424, Indonesia |
Radiotherapy is one of the treatments for nasopharyngeal cancer (NPC). However, this treatment might produce an unfavorable effect on the thyroid gland, which eventually results in less production of thyroid hormone. This is condition is known as hypothyroidism. The development of hypothyroidism in each patient with post-radiative NPC differs according to several factors. This study aims to analyze the rate of development of hypothyroidism in post-radiated NPC patients. This aim is achieved by identifying subgroups of patients with different hazard rates of developing hypothyroidism, and further identify factors explaining hypothyroidism in each subgroup. Data on ninety-seven NPC post-radiation patients taken from one of the hospitals in Jakarta were analyzed. Survival tree with the relative risk tree algorithm was proposed to analyze the data. We identified three subgroups of patients with relatively slow, medium, and fast developing of hypothyroidism. For the slow subgroup, 26% of the patients developed hypothyroidism at 150+ weeks post-radiation, while it only took less than 30 weeks for those in fast-growing subgroup; and 70 until 130 weeks for the medium subgroup. We also found that sweat production and Zulewski's total score were the important factors in explaining the development rate of hypothyroidism. © 2021 Institute of Physics Publishing. All rights reserved. |
|
Clustering algorithms; Diseases; Forestry; Information analysis; Radiotherapy; Development rate; Hazard rates; Jakarta; Nasopharyngeal cancer; Relative risks; Thyroid glands; Thyroid hormones; Tree algorithms; Trees (mathematics) |
IOP Publishing Ltd |
17426588 |
|
|
Conference Paper |
Q4 |
210 |
18731 |
|
|
|
623 |
Winarto H. |
54080645300; |
The importance of identification for a stress urinary incontinence after pelvic orgaprolapse vaginal repair |
2021 |
Medical Journal of Indonesia |
30 |
4 |
|
237 |
238 |
|
|
https://www.scopus.com/inward/record.uri?eid=2-s2.0-85123709235&doi=10.13181%2fmji.ed.215971&partnerID=40&md5=ee09f6c4f49a5e6e13609c2191a488f0 |
Medical Journal of Indonesia, Department of Obstetrics and Gynecology, Faculty of Medicine, Universitas Indonesia, Cipto Mangunkusumo Hospital, Jakarta, Indonesia |
Winarto, H., Medical Journal of Indonesia, Department of Obstetrics and Gynecology, Faculty of Medicine, Universitas Indonesia, Cipto Mangunkusumo Hospital, Jakarta, Indonesia |
[No abstract available] |
|
editorial; Editorial; female; human; pelvic organ prolapse; postoperative complication; stress incontinence; vagina reconstruction |
Faculty of Medicine, Universitas Indonesia |
08531773 |
|
|
Editorial |
Q4 |
164 |
21905 |
|
|
|
625 |
Lukito W. |
6701622348; |
Current Evidence in Water and Hydration Science |
2021 |
Annals of nutrition & metabolism |
77 |
|
|
1 |
6 |
|
|
https://www.scopus.com/inward/record.uri?eid=2-s2.0-85125594947&doi=10.1159%2f000521769&partnerID=40&md5=dc03696320911a4943e24730854d46e4 |
Postgraduate Program in Physician Specialist-I in Clinical Nutrition/Department of Nutrition, Faculty of Medicine, Universitas IndonesiaJakarta, Indonesia |
Lukito, W., Postgraduate Program in Physician Specialist-I in Clinical Nutrition/Department of Nutrition, Faculty of Medicine, Universitas IndonesiaJakarta, Indonesia |
[No abstract available] |
|
|
NLM (Medline) |
14219697 |
|
35226915 |
Editorial |
#N/A |
#N/A |
#N/A |
|
|
|
641 |
Rustamadji P., Wiyarta E., Bethania K.A. |
55321572200;57221521342;57226320454; |
CD44 Variant Exon 6 Isoform Expression as a Potential Predictor of Lymph Node Metastasis in Invasive Breast Carcinoma of No Special Type |
2021 |
International Journal of Breast Cancer |
2021 |
|
1586367 |
|
|
|
|
https://www.scopus.com/inward/record.uri?eid=2-s2.0-85122178964&doi=10.1155%2f2021%2f1586367&partnerID=40&md5=d1d81f9245419dc6421070e419983e36 |
Department of Anatomic Pathology, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia |
Rustamadji, P., Department of Anatomic Pathology, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Wiyarta, E., Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Bethania, K.A., Department of Anatomic Pathology, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia |
Background. Invasive breast carcinoma of no special type (IBC-NST) is the most widespread invasive carcinoma subtype causing primarily regional metastases of the lymphatic node (LNM). The capacity of CD44 variant exon 6 (CD44v6) expression as an LNM predictor biomarker in IBC-NST was explored. Methods. We conducted a cross-sectional research with 48 paraffin blocks containing IBC-NST primary tumors that were divided into two groups by LNM. The assessment has been carried out in terms of age, tumor size, tumor grade, lymphovascular invasion (LVI), and CD44v6 expression. The expression of CD44v6 was analyzed on the grounds of immunohistochemical (IHC) staining, while other data were taken from archives. Statistical analysis is carried out by univariate, multivariate, and AUROC. Results. CD44v6 exhibits a dominant expression in IBC-NST tumor cells. Univariate analysis revealed a significant association between CD44v6 and LNM status (p=0.001). Multiple logistic regression results showed that CD44v6 expression and LVI were significantly associated with LNM with OR 10.7 (95% CI: 2.43 to 47.08) and 6.22 (95% CI: 1.4 to 27.88), respectively. CD44v6 expression was able to discriminate against LNM with AUROC 0.863±0.053 (95% CI: 0.759 to 0.967) at the H-score cut-off 133.889 (75% sensitivity and 83.3% specificity). Conclusion. CD44v6 expression and LVI are potential predictors of LNM in IBC-NST. The H-score cut-off of the CD44v6 expression can also be used as a threshold for classification in further investigation. © 2021 Primariadewi Rustamadji et al. |
|
|
Hindawi Limited |
20903170 |
|
|
Article |
Q3 |
552 |
9149 |
|
|
