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291	Rosana M., Asmara O.D., Pribadi R.R., Kalista K.F., Harimurti K.	57310736300;57311469800;57194732282;57200425631;23473513200;	Internal Medicine Residents' Perceptions of Point-of-Care Ultrasound in Residency Program: Highlighting the Unmet Needs	2021	Acta medica Indonesiana	53	3	299	307		https://www.scopus.com/inward/record.uri?eid=2-s2.0-85117823517&partnerID=40&md5=913ad9734aff00b93a00fe56082dca20	Department of Internal Medicine, Faculty of Medicine Universitas Indonesia, Cipto Mangunkusumo National General HospitalJakarta, Indonesia	Rosana, M., Department of Internal Medicine, Faculty of Medicine Universitas Indonesia, Cipto Mangunkusumo National General HospitalJakarta, Indonesia; Asmara, O.D.; Pribadi, R.R.; Kalista, K.F.; Harimurti, K.	BACKGROUND: Point-of-care ultrasound (POCUS) is increasingly used in internal medicine field. Ultrasound training has been part of the training provided in the Internal Medicine Residency Program (IMRP). The aim of this study is to examine the residents' needs and perceptions regarding their competency and needs of POCUS. METHODS: We conducted a cross-sectional descriptive study using secondary data from a survey among internal medicine residents at the Faculty of Medicine Universitas Indonesia, Cipto Mangunkusumo National General Hospital. The survey was conducted to evaluate and improve the curriculum in IMRP. RESULTS: A total of 175 out of 197 residents (88.8%) completed the questionnaire. Almost all the residents (99.4%) agreed that POCUS is a beneficial must-have skill during residency. Nevertheless, only 40% of residents identified themselves as competent in POCUS. Sixty-two percent residents reckoned that the training received during the residency program is insufficient. They indicated that the most useful skills are US of hepatobiliary, lungs, heart, kidneys, and US-guided procedures. CONCLUSION: This study confirms that there is a need for POCUS training for IM residents, as the majority perceived themselves as unable to perform US. It is necessary to optimize the training provided to ensure proficiency.	internal medicine; Internship; residency; ultrasonography	adult; article; curriculum; female; general hospital; heart; human; human experiment; Indonesia; internal medicine; kidney; lung; male; perception; point of care ultrasound; questionnaire; resident; skill	NLM (Medline)	01259326	34611069	Article	Q3	321	14162	View
292	Iman R.P., Junita T., Rachman R.I., Syam A.F.	57218324172;57310672300;57310137500;8443384400;	Risk factor, diagnosis, and current treatment of H. pylori Infection in Indonesia: A Literature Review	2021	Acta medica Indonesiana	53	3	331	338		https://www.scopus.com/inward/record.uri?eid=2-s2.0-85117760916&partnerID=40&md5=ce13806d99f6c0a46477f70903de63ef	Faculty of Medicine Universitas IndonesiaJakarta, Indonesia	Iman, R.P., Faculty of Medicine Universitas IndonesiaJakarta, Indonesia; Junita, T.; Rachman, R.I.; Syam, A.F.	Helicobacter pylori (H. pylori) infection has become an emerging problem in Indonesia despite its relatively low prevalence as opposed to other Southeast Asian and Asian countries. Strains containing less virulent genotypes predominantly found in Indonesia is suggested to be the rationale for why the disease prevalence, as well as its gastric cancer complication, remain inferior in respect of neighboring counterparts. Although endoscopic evaluation is still necessary to determine the gastric mucosal status of those infected with H. pylori, the infection itself can be easily diagnosed with test-and-treat strategy especially in areas with limited resources. Several findings revealed high rates of antibiotic resistance varying among Indonesian regions and ethnicities, suggesting that triple therapy regimen may not be suitable for all population. Whereas treatment should be based on the pattern of resistance in respected region, novel regimens involving furazolidone, rifabutin, and sitafloxacin are proposed as potential drugs of choice to eradicate H. pylori infection. In order to determine the adequate approach for H. pylori infection in Indonesia, further multicenter studies involving larger sample size should be conducted.	current treatment; diagnosis; Helicobacter pylori; infection; risk factor		NLM (Medline)	01259326	34611074	Article	Q3	321	14162	View
293	Saifuddin A., Koesnoe S., Kurniati N., Sirait S., Arisanty R., Yunihastuti E.	57217827222;26028015000;57310154400;56426927400;57204115712;57221273925;	COVID Arm After Moderna Booster in Healthcare Worker: A Case Report	2021	Acta medica Indonesiana	53	3	326	330	3	https://www.scopus.com/inward/record.uri?eid=2-s2.0-85117747171&partnerID=40&md5=f3f6d4890049ab19cad5ba0a8a16a045	Division of Allergy and Clinical Immunology, Department of Internal Medicine, Faculty of Medicine Universitas Indonesia - Cipto Mangunkusumo HospitalJakarta, Indonesia	Saifuddin, A., Division of Allergy and Clinical Immunology, Department of Internal Medicine, Faculty of Medicine Universitas Indonesia - Cipto Mangunkusumo HospitalJakarta, Indonesia; Koesnoe, S.; Kurniati, N.; Sirait, S.; Arisanty, R.; Yunihastuti, E.	SARS CoV-2 virus has infected more than 200 million people worldwide and more than 4.4 million in Indonesia. The vaccination program has become one of the solutions launched by many countries globally, including Indonesia, to reduce the transmission rate of COVID-19. Various vaccination platforms are produced, such as inactivated, viral vector, mRNA, and protein subunit. The vaccination booster program with mRNA platform (Moderna) was launched by the Indonesian government to give better protection for health care workers, particularly from delta variant. In this case report, we discuss one of the typical side effects of Moderna vaccine, which is referred to as the COVID arm.	booster; COVID arm; COVID-19; healthcare worker; Moderna; vaccination	analgesic agent; elasomeran; paracetamol; administration and dosage; adverse drug reaction; adverse event; biopsy; case report; delayed hypersensitivity; epidemiology; female; fever; human; injection site reaction; middle aged; pathology; pathophysiology; physician; prevention and control; procedures; skin; treatment outcome; vaccination; Acetaminophen; Analgesics, Non-Narcotic; Biopsy; COVID-19; COVID-19 Vaccines; Drug-Related Side Effects and Adverse Reactions; Female; Fever; Humans; Hypersensitivity, Delayed; Injection Site Reaction; Middle Aged; Physicians; SARS-CoV-2; Skin; Treatment Outcome; Vaccination	NLM (Medline)	01259326	34611073	Article	Q3	321	14162	View
294	Nelwan E.J., Tunjungputri R.N., Wardani R.S., Wahyuningsih R.	14527452900;56342194400;47562102900;6507268400;	Black Fungus Complicated with COVID-19 in a Man with Underlying Non-Hodgkin's Lymphoma	2021	Acta medica Indonesiana	53	3	349	351		https://www.scopus.com/inward/record.uri?eid=2-s2.0-85117746727&partnerID=40&md5=9ffcb6f5c08a7096c40aca053f41d236	1. Division of Tropical and Infectious Disease. Department of Internal Medicine, Indonesia. 2. Department of Internal Medicine, Faculty of Medicine Universitas Indonesia - Cipto Mangunkusumo HospitalJakarta, Indonesia	Nelwan, E.J., 1. Division of Tropical and Infectious Disease. Department of Internal Medicine, Indonesia. 2. Department of Internal Medicine, Faculty of Medicine Universitas Indonesia - Cipto Mangunkusumo HospitalJakarta, Indonesia; Tunjungputri, R.N.; Wardani, R.S.; Wahyuningsih, R.	COVID-19 is a disease reported to suppress cellular immunity. This may lead to the development of opportunistic infections, among others black fungus, or mucormycosis. On the other hand, pre-existing defect in immunity may render patients susceptible to both mucormycosis and COVID-19. Mucormycosis is a relatively rare fungal infection with rapid progression unless diagnosed promptly and treated adequately, and urgent surgical and medical intervention is lifesaving. The manifestation of mucormycosis largely depends on the presence of exposure to the pathogen and the existing risk factor of the host. As black fungus is locally invasive, the majority of cases will involve tissue damage with local destruction and contiguous spread to nearby structure. We here with present a case of black fungus complicated with COVID-19 in a man with underlying non-Hodgkin's lymphoma.	black fungus; COVID-19; non-hodgkin lymphoma	adult; biopsy; case report; complication; debridement; diagnosis; disease exacerbation; human; isolation and purification; male; microbiology; Mucorales; mucormycosis; nonhodgkin lymphoma; nose disease; nose septum; pathology; pathophysiology; patient isolation; procedures; therapy; time to treatment; x-ray computed tomography; Adult; Biopsy; COVID-19; Debridement; Disease Progression; Humans; Lymphoma, Non-Hodgkin; Male; Mucorales; Mucormycosis; Nasal Septum; Nose Diseases; Patient Isolation; SARS-CoV-2; Time-to-Treatment; Tomography, X-Ray Computed	NLM (Medline)	01259326	34611076	Article	Q3	321	14162	View
443	Shatri H., Putranto R., Faisal E., Fitrianti F., Adhiatma K., Zulmiyusrini P., Diba S.F., Lukman P.R.	28767986500;56074051000;57218497073;57226626294;57226627483;57208105781;57226627082;55981460300;	Psychotherapy for Healthcare Provider During COVID-19 Pandemic: An Evidence Based Clinical Review	2021	Acta medica Indonesiana	53	2	225	232	1	https://www.scopus.com/inward/record.uri?eid=2-s2.0-85112125259&partnerID=40&md5=67ed7e7351b78d9ad3f635d4564bfa25	1. Division of Psychosomatic and Palliative, Faculty of Medicine Universitas Indonesia - Cipto Mangunkusumo Hospital Jakarta, Indonesia. 2. Clinical Epidemiology Unit, Department of Internal Medicine, Faculty of Medicine Universitas Indonesia - Cipto Mangunkusumo HospitalJakarta, Indonesia	Shatri, H., 1. Division of Psychosomatic and Palliative, Faculty of Medicine Universitas Indonesia - Cipto Mangunkusumo Hospital Jakarta, Indonesia. 2. Clinical Epidemiology Unit, Department of Internal Medicine, Faculty of Medicine Universitas Indonesia - Cipto Mangunkusumo HospitalJakarta, Indonesia; Putranto, R.; Faisal, E.; Fitrianti, F.; Adhiatma, K.; Zulmiyusrini, P.; Diba, S.F.; Lukman, P.R.	BACKGROUND: health workers are one of the groups affected physically as well as psychologically from the pandemic. Recent studies showed many of the health workers reported experiencing anxiety, depression, and insomnia. This study aims to identify psychotherapy as a psychological health intervention, for healthcare workers during the COVID-19 pandemic. METHODS: an evidence based clinical review of psychotherapy as a psychological health intervention, reported in the literature, which is developed for healthcare workers during the COVID-19 pandemic. The review was conducted following set out for Evidence-based clinical review by searching the following digital libraries: PubMed, ProQuest, Cochrane, and Google Scholar. RESULTS: six publications were selected. The identified psychotherapy used as a mental or psychological intervention for healthcare workers during COVID-19 consists of supportive psychotherapy, psychoeducation, social support, and music therapy. Overall, it shows that psychotherapy, especially supportive psychotherapy, can reduce anxiety, depression, and insomnia. CONCLUSION: the physiological condition of health workers needs to get attention during the COVID-19 pandemic. Although there is no standard of therapy yet, psychotherapy could be an option as it is proven to be able to reduce anxiety, depression, and insomnia.	COVID-19; healthcare workers; internal medicine; medical journal; psychosomatic; psychotherapy	epidemiology; evidence based medicine; health care personnel; human; pandemic; psychology; psychotherapy; COVID-19; Evidence-Based Medicine; Health Personnel; Humans; Pandemics; Psychotherapy; SARS-CoV-2	NLM (Medline)	01259326	34251353	Review	Q3	321	14162	View
444	Wardoyo E.Y., Nainggolan G., Hustrini N.M., Setiati S.	57219411333;23498775400;57200424892;14325991900;	Factors Associated with Arterial Stiffness in Chronic Hemodialysis Patients in Jakarta: The Role of Hemodialysis Frequency and Pentraxin 3	2021	Acta medica Indonesiana	53	2	177	183		https://www.scopus.com/inward/record.uri?eid=2-s2.0-85111583410&partnerID=40&md5=48c271443cfc8fc3a9b8370bf863e403	Department of Internal Medicine, Faculty of Medicine Universitas IndonesiaJakarta, Indonesia	Wardoyo, E.Y., Department of Internal Medicine, Faculty of Medicine Universitas IndonesiaJakarta, Indonesia; Nainggolan, G.; Hustrini, N.M.; Setiati, S.	BACKGROUND: arterial stiffness is a mortality predictor in hemodialysis patients, hemodialysis induces inflammation, marked by an intradialysis increase in the inflammatory marker pentraxin 3 (PTX3). Arterial stiffness in twice-weekly hemodialysis patients in Indonesia is lower than has been found in studies of thrice-weekly patients. This study therefore aims to determine the factors associated with arterial stiffness, focusing on the role of hemodialysis frequency and PTX3. METHODS: a cross-sectional study was conducted at Cipto Mangunkusumo Hospital, Fatmawati Hospital, and Medistra Hospital involving patients with twice- and thrice-weekly hemodialysis. Arterial stiffness was measured by carotid-femoral pulse wave velocity after hemodialysis, and blood samples for PTX3 testing were taken before hemodialysis. Bivariate and multivariate analyses were performed using chi-squared tests and logistic regression. RESULTS: out of 122 subjects, 82 underwent twice-weekly hemodialysis. There was no difference in arterial stiffness between patients with twice- and thrice-weekly hemodialysis. In bivariate analysis, PTX3, cardiovascular disease, dialysis vintage had p values of <0.05, while the subsequent multivariate analysis showed that PTX3>2.3 ng/ml was associated with arterial stiffness (adjusted OR 5.18; 95% CI 1.07-24.91), as well as cardiovascular disease (adjusted OR 3.67; 95% CI 1.40-10.55), LDL (adjusted OR 3.10; 95% CI 1.04-9.24), and dialysis vintage (adjusted OR 2.72; 95% CI 1.001-7.38). CONCLUSION: predialysis PTX3 levels above 2.3 ng/ml were associated with arterial stiffness. There was no difference in arterial stiffness between patients with twice- and thrice-weekly hemodialysis.	arterial stiffness; hemodialysis frequency; pentraxin 3; pulse wave velocity	biological marker; C reactive protein; pentraxin 3; serum amyloid P; adult; aged; arterial stiffness; blood; blood flow velocity; chronic kidney failure; clinical trial; cross-sectional study; female; hemodialysis; human; Indonesia; male; metabolism; middle aged; multicenter study; multivariate analysis; physiology; pulse wave; statistical model; Adult; Aged; Biomarkers; Blood Flow Velocity; C-Reactive Protein; Cross-Sectional Studies; Female; Humans; Indonesia; Kidney Failure, Chronic; Logistic Models; Male; Middle Aged; Multivariate Analysis; Pulse Wave Analysis; Renal Dialysis; Serum Amyloid P-Component; Vascular Stiffness	NLM (Medline)	01259326	34251346	Article	Q3	321	14162	View
445	Pramono L.A., Yunir E., Tarigan T.J.E., Nusanti S., Aman R.A., Suroyo I.	37063602400;36520254800;36057746500;57189727162;57226434769;57204106272;	Giant Recurrence Pituitary Adenoma After Three Times Transphenoidal Removal Surgery, One Craniotomy Procedure, and 30 Doses of External Radiotherapy	2021	Acta medica Indonesiana	53	2	221	224		https://www.scopus.com/inward/record.uri?eid=2-s2.0-85111572434&partnerID=40&md5=3fbf4691ce27b57e71d3a91134445173	1. Department of Internal Medicine, Faculty of Medicine Universitas Indonesia - Cipto Mangunkusumo Hospital, Indonesia. 2. Department of Public Health and Nutrition, School of Medicine and Health Sciences Universitas Katolik Indonesia Atma Jaya - Department of Internal Medicine St Carolus HospitalJakarta, Indonesia	Pramono, L.A., 1. Department of Internal Medicine, Faculty of Medicine Universitas Indonesia - Cipto Mangunkusumo Hospital, Indonesia. 2. Department of Public Health and Nutrition, School of Medicine and Health Sciences Universitas Katolik Indonesia Atma Jaya - Department of Internal Medicine St Carolus HospitalJakarta, Indonesia; Yunir, E.; Tarigan, T.J.E.; Nusanti, S.; Aman, R.A.; Suroyo, I.	This is a case of 42nd year-old woman with history of sight loss in her both eyes. She experienced headache and visual field decrease gradually since 2014. After several laboratory and imaging examinations, from her dynamic pituitary magnetic resonance imaging (MRI), it is concluded that she had a giant adenoma of the pituitary gland which compressed to her optic chiasm. From her pituitary laboratory hormone panel, it is revealed that the tumor is a non-functioning pituitary adenoma. From the neuro-ophthalmology (campimetry) examinations, she had papillae atrophy in her both eyes and also bilateral temporal hemianopia.	Giant Recurrence Pituitary Adenoma; Radiotherapy; Transphenoidal Removal Surgery	adenoma; adult; case report; craniotomy; female; hemianopia; human; hypophysis tumor; nuclear magnetic resonance imaging; optic nerve; pathology; tumor recurrence; Adenoma; Adult; Craniotomy; Female; Hemianopsia; Humans; Magnetic Resonance Imaging; Neoplasm Recurrence, Local; Optic Nerve; Pituitary Neoplasms	NLM (Medline)	01259326	34251352	Article	Q3	321	14162	View
446	Damanik J., Yunir E.	57211582841;36520254800;	Type 2 Diabetes Mellitus and Cognitive Impairment	2021	Acta medica Indonesiana	53	2	213	220		https://www.scopus.com/inward/record.uri?eid=2-s2.0-85111560209&partnerID=40&md5=8b6a3af63f3b7bd6c8c50f2cf6ec2509	Department of Internal Medicine, Faculty of Medicine Universitas Indonesia - Cipto Mangunkusumo HospitalJakarta, Indonesia	Damanik, J., Department of Internal Medicine, Faculty of Medicine Universitas Indonesia - Cipto Mangunkusumo HospitalJakarta, Indonesia; Yunir, E.	Type 2 diabetes mellitus (T2DM) is strongly associated with lower performance on multiple domains of cognitive function and with structural abnormalities of the brain. With the growing epidemic of diabetes and aging population, neural complications of diabetes are expected to rise and becoming a challenge for future health implications. Understanding pathophysiology, factors associated with this complication, manifestation of cognitive impairment and various metabolic and neuroradiologic markers suggestive of this pathologic condition is crucial for proper management of this potentially debilitating complication of T2DM. This review will discuss briefly important aspects of cognitive impairment in T2DM.	cognitive impairment; type 2 diabetes mellitus	biological marker; aged; brain; cognition; human; non insulin dependent diabetes mellitus; pathology; pathophysiology; Aged; Biomarkers; Brain; Cognition; Diabetes Mellitus, Type 2; Humans	NLM (Medline)	01259326	34251351	Review	Q3	321	14162	View
447	Nugroho P., Lydia A., Suhardjono S., Harimurti K.	55987056300;8451287200;57218776121;23473513200;	Association of BsmI Polymorphisms in the Vitamin D Receptor Gene Among Indonesian Population with Diabetic Kidney Disease	2021	Acta medica Indonesiana	53	2	149	155		https://www.scopus.com/inward/record.uri?eid=2-s2.0-85111468637&partnerID=40&md5=791ec67dac5f5065a522a04484329da4	Division of Nephrology and Hypertension, Indonesia. 2. Clinical Epidemiology Unit, Department of Internal Medicine, Faculty of Medicine, Universitas Indonesia-Dr Cipto Mangunkusumo HospitalJakarta, Indonesia	Nugroho, P., Division of Nephrology and Hypertension, Indonesia. 2. Clinical Epidemiology Unit, Department of Internal Medicine, Faculty of Medicine, Universitas Indonesia-Dr Cipto Mangunkusumo HospitalJakarta, Indonesia; Lydia, A.; Suhardjono, S.; Harimurti, K.	BACKGROUND: Diabetic kidney disease (DKD), as a common cause of end-stage renal disease (ESRD), is a chronic complication of diabetes mellitus (DM). It has been established that vitamin D deficiency is one of DKD risk factors, which may be related to vitamin D receptor (VDR) polymorphisms. This study aimed to analyze the association between VDR polymorphisms and DKD in Indonesian population, also risk factors that influence it. METHODS: a cross-sectional study was conducted in Type 2 DM patients who visited internal medicine outpatient clinic at Dr. Cipto Mangunkusumo Hospital, Jakarta, from November 2014 until March 2015. Data collection includes characteristics of subjects and laboratory examination, including BsmI polymorphisms in the vitamin D receptor gene. Patients with acute and severe disease were excluded from the study. Bivariate and multivariate analyses were done. RESULTS: of 93 DM subjects, 42 (45.2%) subjects were without DKD and 51 (54.8%) subjects had DKD. Most of the subjects had the Bb genotype (89.2%), with no subject having the BB genotype. The proportions of the B and b alleles were 44.6% and 55.4%, respectively. There is no association between BsmI polymorphisms in the vitamin D receptor gene and DKD (OR = 1.243; CI 95% 0.334-4.621; p value = 0.751). CONCLUSION: the profile of BsmI polymorphisms in the vitamin D receptor gene in the Indonesian population were genotypes Bb (89.2%) and bb (10.8%). There was no association between BsmI polymorphisms in the vitamin D receptor gene and DKD. Duration of DM more than five years influenced the association between those variables.	BsmI; diabetic kidney disease; Indonesia-Malay race; polymorphisms; vitamin D receptor (VDR) gene	calcitriol receptor; VDR protein, human; aged; blood; case control study; complication; cross-sectional study; diabetic nephropathy; female; genetic polymorphism; genetics; genotype; human; Indonesia; male; middle aged; non insulin dependent diabetes mellitus; risk factor; very elderly; Aged; Aged, 80 and over; Case-Control Studies; Cross-Sectional Studies; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Female; Genotype; Humans; Indonesia; Male; Middle Aged; Polymorphism, Genetic; Receptors, Calcitriol; Risk Factors	NLM (Medline)	01259326	34251342	Article	Q3	321	14162	View
448	Syam A.F., Pitoyo C.W., Suhendro S., Zulkarnain B., Indrasari N.D., Aditianingsih D., Irawan C., Susilo A., Rumende C.M., Wijaya I.P., Ibrahim F., Rasmin M., Alwi I., Makmun D.	8443384400;26022606900;8443626100;57226403717;6506289872;56312263600;28767651600;57217867079;14325966300;57221504958;57226400046;15754578700;15055173800;16638046900;	Tocilizumab as a Treatment for 'Cytokine Storm Syndrome' in COVID-19: A Case Report	2021	Acta medica Indonesiana	53	2	194	201		https://www.scopus.com/inward/record.uri?eid=2-s2.0-85111460182&partnerID=40&md5=9fddc7ae8a7dbf93ea0a07158c0ab2b2	Fellow of the American College of Physicians; Division of Gastroenterology, Dept. of Internal Medicine, Faculty of Medicine Universitas Indonesia - Cipto Mangunkusumo Hospital, Jakarta, Indonesia	Syam, A.F., Fellow of the American College of Physicians; Division of Gastroenterology, Dept. of Internal Medicine, Faculty of Medicine Universitas Indonesia - Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Pitoyo, C.W.; Suhendro, S.; Zulkarnain, B.; Indrasari, N.D.; Aditianingsih, D.; Irawan, C.; Susilo, A.; Rumende, C.M.; Wijaya, I.P.; Ibrahim, F.; Rasmin, M.; Alwi, I.; Makmun, D.	Coronavirus disease 19 (COVID-19) which is caused by Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2), has been a problem worldwide, particularly due to the high rate of transmission and wide range of clinical manifestations. Acute respiratory distress syndrome (ARDS) and multiorgan failure are the most common events observed in severe cases and can be fatal. Cytokine storm syndrome emerges as one of the possibilities for the development of ARDS and multiorgan failure in severe cases of COVID-19. This case report describes a case of a 53-year-old male patient who has been diagnosed with COVID-19. Further evaluation in this patient showed that there was a marked increase in IL-6 level in blood accompanied with hyperferritinemia, which was in accordance with the characteristic of cytokine storm syndrome. Patient was treated with tocilizumab, a monoclonal antibody and is an antagonist to IL-6 receptor. The binding between tocilizumab and IL-6 receptors effectively inhibit and manage cytokine storm syndrome. Although this case report reported the efficacy of tocilizumab in managing cytokine storm syndrome, tocilizumab has several adverse effects requiring close monitoring. Further clinical randomized control trial is required to evaluate the efficacy and safety of tocilizumab administration in participants with various clinical characteristics and greater number of subjects.	acute respiratory distress syndrome (ARDS); COVID-19; SARS-CoV-2; Tocilizumab	biological marker; interleukin 6; monoclonal antibody; tocilizumab; blood; case report; complication; cytokine release syndrome; human; male; middle aged; Antibodies, Monoclonal, Humanized; Biomarkers; COVID-19; Cytokine Release Syndrome; Humans; Interleukin-6; Male; Middle Aged; SARS-CoV-2	NLM (Medline)	01259326	34251348	Article	Q3	321	14162	View

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