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80 |
Paramita R.I., Nelwan E.J., Fadilah F., Renesteen E., Puspandari N., Erlina L. |
54882436900;14527452900;56966708600;57216633036;56786591900;57190181680; |
Genome-based characterization of Escherichia coli causing bloodstream infection through next-generation sequencing |
2021 |
PLoS ONE |
15 |
12 December |
e0244358 |
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5 |
https://www.scopus.com/inward/record.uri?eid=2-s2.0-85099074536&doi=10.1371%2fjournal.pone.0244358&partnerID=40&md5=4997d32055c7a3e5834f747ae4be685e |
Department of Medical Chemistry, Faculty of Medicine, Universitas Indonesia, DKI Jakarta, Indonesia; Bioinformatics Core Facilities-IMERI, Faculty of Medicine, Universitas Indonesia, DKI Jakarta, Indonesia; Master's Programme in Biomedical Sciences, Faculty of Medicine, Universitas Indonesia, DKI Jakarta, Indonesia; Department of Internal Medicine, Faculty of Medicine, Universitas Indonesia, DKI Jakarta, Indonesia; Infectious Disease and Immunology Research Center-IMERI, Faculty of Medicine, Universitas Indonesia, DKI Jakarta, Indonesia; Centre for Research and Development of Biomedical and Basic Health Technology, National Institute of Health Research and Development, Ministry of Health, DKI Jakarta, Indonesia |
Paramita, R.I., Department of Medical Chemistry, Faculty of Medicine, Universitas Indonesia, DKI Jakarta, Indonesia, Bioinformatics Core Facilities-IMERI, Faculty of Medicine, Universitas Indonesia, DKI Jakarta, Indonesia, Master's Programme in Biomedical Sciences, Faculty of Medicine, Universitas Indonesia, DKI Jakarta, Indonesia; Nelwan, E.J., Department of Internal Medicine, Faculty of Medicine, Universitas Indonesia, DKI Jakarta, Indonesia, Infectious Disease and Immunology Research Center-IMERI, Faculty of Medicine, Universitas Indonesia, DKI Jakarta, Indonesia; Fadilah, F., Department of Medical Chemistry, Faculty of Medicine, Universitas Indonesia, DKI Jakarta, Indonesia, Bioinformatics Core Facilities-IMERI, Faculty of Medicine, Universitas Indonesia, DKI Jakarta, Indonesia, Master's Programme in Biomedical Sciences, Faculty of Medicine, Universitas Indonesia, DKI Jakarta, Indonesia; Renesteen, E., Infectious Disease and Immunology Research Center-IMERI, Faculty of Medicine, Universitas Indonesia, DKI Jakarta, Indonesia; Puspandari, N., Centre for Research and Development of Biomedical and Basic Health Technology, National Institute of Health Research and Development, Ministry of Health, DKI Jakarta, Indonesia; Erlina, L., Department of Medical Chemistry, Faculty of Medicine, Universitas Indonesia, DKI Jakarta, Indonesia, Bioinformatics Core Facilities-IMERI, Faculty of Medicine, Universitas Indonesia, DKI Jakarta, Indonesia, Master's Programme in Biomedical Sciences, Faculty of Medicine, Universitas Indonesia, DKI Jakarta, Indonesia |
Escherichia coli are one of the commonest bacteria causing bloodstream infection (BSI). The aim of the research was to identify the serotypes, MLST (Multi Locus Sequence Type), virulence genes, and antimicrobial resistance of E. coli isolated from bloodstream infection hospitalized patients in Cipto Mangunkusumo National Hospital Jakarta. We used whole genome sequencing methods rather than the conventional one, to characterized the serotypes, MLST (Multi Locus Sequence Type), virulence genes, and antimicrobial resistance (AMR) of E. coli. The composition of E. coli sequence types (ST) was as follows: ST131 (n=5), ST38 (n=3), ST405 (n=3), ST69 (n=3), and other STs (ST1057, ST127, ST167, ST3033, ST349, ST40, ST58, ST6630). Enteroaggregative E. coli (EAEC) and Extra-intestinal pathogenic E. coli (ExPEC) groups were found dominant in our samples. Twenty isolates carried virulence genes for host cells adherence and 15 for genes that encourage E. coli immune evasion by enhancing survival in serum. ESBL-genes were present in 17 E. coli isolates. Other AMR genes also encoded resistance against aminoglycosides, quinolones, chloramphenicol, macrolides and trimethoprim. The phylogeny analysis showed that phylogroup D is dominated and followed by phylogroup B2. The E. coli isolated from 22 patients in Cipto Mangunkusumo National Hospital Jakarta showed high diversity in serotypes, sequence types, virulence genes, and AMR genes. Based on this finding, routinely screening all bacterial isolates in health care facilities can improve clinical significance. By using Whole Genome Sequencing for laboratory-based surveillance can be a valuable early warning system for emerging pathogens and resistance mechanisms. © 2020 Paramita et al. |
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aminoglycoside antibiotic agent; beta lactam antibiotic; chloramphenicol; macrolide; quinoline derived antiinfective agent; trimethoprim; virulence factor; antibiotic resistance; Article; bacterial gene; bacterial genome; bacterial virulence; bacterium isolate; bloodstream infection; cell adhesion; clinical article; DNA isolation; enteroaggregative Escherichia coli; Escherichia coli; extraintestinal pathogenic Escherichia coli; gene isolation; gene sequence; genetic code; high throughput sequencing; hospital patient; host cell; human; Indonesia; multilocus sequence typing; nonhuman; nuclear magnetic resonance; phylogeny; serotype; virulence gene; whole genome sequencing; bacteremia; bacterial genome; classification; Escherichia coli; Escherichia coli infection; genetics; high throughput se |
Public Library of Science |
19326203 |
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33362261 |
Article |
Q1 |
990 |
4434 |
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498 |
Supriadi S., Rachman P., Saragih A.S., Whulanza Y., Rahyussalim A.J., Triwidodo A. |
16040272500;57222619791;24339579800;36807053500;55212166100;57222626174; |
Design, development, and finite element study on the novel biomimetic lumbosacroiliac prosthesis |
2021 |
AIP Conference Proceedings |
2344 |
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050021 |
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5 |
https://www.scopus.com/inward/record.uri?eid=2-s2.0-85103512681&doi=10.1063%2f5.0047182&partnerID=40&md5=ceda670f69efa9020569efb213e95b5e |
Department of Mechanical Engineering, Faculty of Engineering, Universitas Indonesia, Kampus UI Depok, West Java, 16424, Indonesia; Research Center for Biomedical Engineering, Faculty of Engineering, Universitas Indonesia, Kampus UI Depok, West Java, 16424, Indonesia; Department of Orthopaedics and Traumatology, Faculty of Medicine, Universitas Indonesia, Cipto Mangunkusumo General Hospital, Jakarta, 10320, Indonesia |
Supriadi, S., Department of Mechanical Engineering, Faculty of Engineering, Universitas Indonesia, Kampus UI Depok, West Java, 16424, Indonesia, Research Center for Biomedical Engineering, Faculty of Engineering, Universitas Indonesia, Kampus UI Depok, West Java, 16424, Indonesia; Rachman, P., Department of Mechanical Engineering, Faculty of Engineering, Universitas Indonesia, Kampus UI Depok, West Java, 16424, Indonesia, Research Center for Biomedical Engineering, Faculty of Engineering, Universitas Indonesia, Kampus UI Depok, West Java, 16424, Indonesia; Saragih, A.S., Department of Mechanical Engineering, Faculty of Engineering, Universitas Indonesia, Kampus UI Depok, West Java, 16424, Indonesia, Research Center for Biomedical Engineering, Faculty of Engineering, Universitas Indonesia, Kampus UI Depok, West Java, 16424, Indonesia; Whulanza, Y., Department of Mechanical Engineering, Faculty of Engineering, Universitas Indonesia, Kampus UI Depok, West Java, 16424, Indonesia, Research Center for Biomedical Engineering, Faculty of Engineering, Universitas Indonesia, Kampus UI Depok, West Java, 16424, Indonesia; Rahyussalim, A.J., Department of Orthopaedics and Traumatology, Faculty of Medicine, Universitas Indonesia, Cipto Mangunkusumo General Hospital, Jakarta, 10320, Indonesia; Triwidodo, A., Department of Orthopaedics and Traumatology, Faculty of Medicine, Universitas Indonesia, Cipto Mangunkusumo General Hospital, Jakarta, 10320, Indonesia |
This study focused on the design of specific prostheses in the case of patients affected by Chordoma of the lumbar 4, lumbar 5, sacrum, and coccyx. A chordoma is a group of malignant and rare cancers, commonly found in the spine or skull bones. As a treatment method, if cancer has not spread beyond the bone, the infected bone's removal procedure is replaced with an artificial bone (prosthesis). The design method is carried out using a CT Scan of patient data, which is processed into a 3D model with Materialise Mimics software, 3D model engineering is done using Solidworks software and finite element analysis with ANSYS. The design process is carried out with several kinds of design variations, including the bone-implant model with a solid and shell model which is divided into several components, the use of iliac screw lateral connector, modification of iliac screw locking head, and modification of iliac screw locking head with cross connector. From the results of the calculation analysis and simulation, the best concept chosen based on the lowest dominant Peak von Mises Stress value in the iliac screw section is designs using the Iliac Screw Locking Head with Shell Model Lattice Structure. © 2021 Author(s). |
3d bone modeling; Chordoma; lumbar; pedicle screw; prosthesis; pull out; sacrum; simulation |
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American Institute of Physics Inc. |
0094243X |
9780735440869 |
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Conference Paper |
- |
177 |
20880 |
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519 |
Dannatt L., Ransing R., Calvey T., Scheibein F., Saad N.A., Shirasaka T., Ramalho R., Pant S., Vadivel R., Siste K., Stowe M.J., Kalita K.N., Boujraf S., Testa R., Arya S., Morgan N., Grandinetti P. |
57200537348;57190296865;55634512900;57212313904;57219875515;7005625709;56789745200;36114863900;57219874702;55644113100;57217388837;54387032200;57220277366;57222475193;35463222300;57201914207;55487378900; |
The Impact of Stigma on Treatment Services for People With Substance Use Disorders During the COVID-19 Pandemic—Perspectives of NECPAM Members |
2021 |
Frontiers in Psychiatry |
12 |
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634515 |
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5 |
https://www.scopus.com/inward/record.uri?eid=2-s2.0-85102821643&doi=10.3389%2ffpsyt.2021.634515&partnerID=40&md5=f473eb1aa0aba07997e39ee4f82c800a |
Department of Psychiatry and Mental Health, University of Cape Town, Cape Town, South Africa; Department of Psychiatry, Bhaktshreshtha Kamalakarpant Laxman (BKL) Walalwalkar Rural Medical College, Pune, India; Faculty of Health Sciences, School of Anatomical Sciences, University of the Witwatersrand, Johannesburg, South Africa; School of Health Science, Waterford Institute of Technology, Waterford, Ireland; State Drug Dependence Treatment Centre, Ain Shams University, Cairo, Egypt; Department of Psychiatry, Teine Keijinkai Medical Center, Sapporo, Japan; Department of Social and Community Health, School of Population Health, University of Auckland, Auckland, New Zealand; Department of Psychiatry, Institute of Medicine, Tribhuvan University, Kirtipur, Nepal; Department of Psychiatry, Medical Faculty, Universitas Indonesia-Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Department of Family Medicine, Faculty of Health Sciences, School of Medicine, University of Pretoria, Pretoria, South Africa; Department of Psychiatry, Lokopriya Gopinath Bordoloi Regional Institute of Mental Health (LGBRIMH), Tezpur, India; Faculty of Medicine and Pharmacy, Sidi Mohamed Ben Abdellah University, Fez, Morocco; Department of Mental Health, Azienda Sanitaria Locale (ASL), 1 Avezzano-L'Aquila-Sulmona, L'Aquila, Italy; State Drug Dependence Treatment Centre, Institute of Mental Health, Pt. Bhagwat Dayal Sharma (BDS), University of Health Sciences, Rohtak, India; Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa; Department of Mental Helth, Azienda Sanitaria Locale (ASL) Teramo, Teramo, Italy |
Dannatt, L., Department of Psychiatry and Mental Health, University of Cape Town, Cape Town, South Africa; Ransing, R., Department of Psychiatry, Bhaktshreshtha Kamalakarpant Laxman (BKL) Walalwalkar Rural Medical College, Pune, India; Calvey, T., Faculty of Health Sciences, School of Anatomical Sciences, University of the Witwatersrand, Johannesburg, South Africa; Scheibein, F., School of Health Science, Waterford Institute of Technology, Waterford, Ireland; Saad, N.A., State Drug Dependence Treatment Centre, Ain Shams University, Cairo, Egypt; Shirasaka, T., Department of Psychiatry, Teine Keijinkai Medical Center, Sapporo, Japan; Ramalho, R., Department of Social and Community Health, School of Population Health, University of Auckland, Auckland, New Zealand; Pant, S., Department of Psychiatry, Institute of Medicine, Tribhuvan University, Kirtipur, Nepal; Vadivel, R.; Siste, K., Department of Psychiatry, Medical Faculty, Universitas Indonesia-Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Stowe, M.J., Department of Family Medicine, Faculty of Health Sciences, School of Medicine, University of Pretoria, Pretoria, South Africa; Kalita, K.N., Department of Psychiatry, Lokopriya Gopinath Bordoloi Regional Institute of Mental Health (LGBRIMH), Tezpur, India; Boujraf, S., Faculty of Medicine and Pharmacy, Sidi Mohamed Ben Abdellah University, Fez, Morocco; Testa, R., Department of Mental Health, Azienda Sanitaria Locale (ASL), 1 Avezzano-L'Aquila-Sulmona, L'Aquila, Italy; Arya, S., State Drug Dependence Treatment Centre, Institute of Mental Health, Pt. Bhagwat Dayal Sharma (BDS), University of Health Sciences, Rohtak, India; Morgan, N., Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa; Grandinetti, P., Department of Mental Helth, Azienda Sanitaria Locale (ASL) Teramo, Teramo, Italy |
[No abstract available] |
access to treatment; COVID-19; mental health; pandemic; stigma; substance use disorder |
benzodiazepine; naloxone; opiate agonist; Article; behavioral addiction; coronavirus disease 2019; drug dependence; drug dependence treatment; harm reduction; health care access; health care planning; health care policy; high risk population; homelessness; human; mental health care; pandemic; practice guideline; social discrimination; social distancing; stigma; vulnerable population |
Frontiers Media S.A. |
16640640 |
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Article |
Q1 |
1363 |
2668 |
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553 |
Turana Y., Tengkawan J., Chia Y.C., Nathaniel M., Wang J.-G., Sukonthasarn A., Chen C.-H., Minh H.V., Buranakitjaroen P., Shin J., Siddique S., Nailes J.M., Park S., Teo B.W., Sison J., Ann Soenarta A., Hoshide S., Tay J.C., Prasad Sogunuru G., Zhang Y., Verma N., Wang T.-D., Kario K., the HOPE Asia Network |
56083326000;57201472878;57204080905;57220063330;57211730247;12793132900;7501963868;57211946145;6603376248;54791393300;57210091066;57204676117;8556278400;23570166200;36764809200;56545726300;6603859769;24330212600;57220061819;56183109800;7102496979;7405566618;7102633390; |
Hypertension and stroke in Asia: A comprehensive review from HOPE Asia |
2021 |
Journal of Clinical Hypertension |
23 |
3 |
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513 |
521 |
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5 |
https://www.scopus.com/inward/record.uri?eid=2-s2.0-85096667710&doi=10.1111%2fjch.14099&partnerID=40&md5=85c747eb49b66c56895a7650e9a82984 |
School of Medicine and Health Sciences, Atma Jaya Catholic University of Indonesia, Jakarta, Indonesia; Department of Medical Sciences, School of Healthcare and Medical Sciences, Sunway University, Bandar Sunway, Malaysia; Department of Primary Care Medicine, Faculty of Medicine, University of Malaya, Kuala Lumpur, Malaysia; Department of Hypertension, Centre for Epidemiological Studies and Clinical Trials, The Shanghai Institute of Hypertension, Shanghai Key Laboratory of Hypertension, Ruijin Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, China; Cardiology Division, Department of Internal Medicine, Faculty of Medicine, Chiang Mai University, Chiang Mai, Thailand; Department of Medicine, Faculty of Medicine, National Yang-Ming University, Taipei, Taiwan; Department of Cardiology, Hue University Hospital, Hue University, Hue City, Viet Nam; Division of Hypertension, Department of Medicine, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand; Faculty of Cardiology Service, Hanyang University Medical Center, Seoul, South Korea; Punjab Medical Center, Lahore, Pakistan; University of the East Ramon Magsaysay Memorial Medical Center Inc., Quezon City, Philippines; Division of Cardiology, Cardiovascular Hospital, Yonsei Health System, Seoul, South Korea; Division of Nephrology, Department of Medicine, Yong Loo Lin School of Medicine, National University of Singapore, Singapore City, Singapore; Division of Nephrology, Department of Medicine, National University Health System, Singapore City, Singapore; Section of Cardiology, Department of Medicine, Medical Center Manila, Manila, Philippines; Department of Cardiology and Vascular Medicine, Faculty of Medicine, University of Indonesia-National Cardiovascular Center, Harapan Kita, Jakarta, Indonesia; Division of Cardiovascular Medicine, Department of Medicine, Jichi Medical University School of Medicine, Tochigi, Japan; Department of General Medicine, Tan Tock Seng Hospital, Singapore, Singapore; MIOT International Hospital, Chennai, India; College of Medical Sciences, Kathmandu University, Bharatpur, Nepal; Divisions of Hypertension and Heart Failure, Fu Wai Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China; Department of Physiology, King George's Medical University, Lucknow, India; Cardiovascular Center and Division of Cardiology, Department of Internal Medicine, National Taiwan University Hospital and National Taiwan University College of Medicine, Taipei City, Taiwan |
Turana, Y., School of Medicine and Health Sciences, Atma Jaya Catholic University of Indonesia, Jakarta, Indonesia; Tengkawan, J., School of Medicine and Health Sciences, Atma Jaya Catholic University of Indonesia, Jakarta, Indonesia; Chia, Y.C., Department of Medical Sciences, School of Healthcare and Medical Sciences, Sunway University, Bandar Sunway, Malaysia, Department of Primary Care Medicine, Faculty of Medicine, University of Malaya, Kuala Lumpur, Malaysia; Nathaniel, M., School of Medicine and Health Sciences, Atma Jaya Catholic University of Indonesia, Jakarta, Indonesia; Wang, J.-G., Department of Hypertension, Centre for Epidemiological Studies and Clinical Trials, The Shanghai Institute of Hypertension, Shanghai Key Laboratory of Hypertension, Ruijin Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, China; Sukonthasarn, A., Cardiology Division, Department of Internal Medicine, Faculty of Medicine, Chiang Mai University, Chiang Mai, Thailand; Chen, C.-H., Department of Medicine, Faculty of Medicine, National Yang-Ming University, Taipei, Taiwan; Minh, H.V., Department of Cardiology, Hue University Hospital, Hue University, Hue City, Viet Nam; Buranakitjaroen, P., Division of Hypertension, Department of Medicine, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand; Shin, J., Faculty of Cardiology Service, Hanyang University Medical Center, Seoul, South Korea; Siddique, S., Punjab Medical Center, Lahore, Pakistan; Nailes, J.M., University of the East Ramon Magsaysay Memorial Medical Center Inc., Quezon City, Philippines; Park, S., Division of Cardiology, Cardiovascular Hospital, Yonsei Health System, Seoul, South Korea; Teo, B.W., Division of Nephrology, Department of Medicine, Yong Loo Lin School of Medicine, National University of Singapore, Singapore City, Singapore, Division of Nephrology, Department of Medicine, National University Health System, Singapore City, Singapore; Sison, J., Section of Cardiology, Department of Medicine, Medical Center Manila, Manila, Philippines; Ann Soenarta, A., Department of Cardiology and Vascular Medicine, Faculty of Medicine, University of Indonesia-National Cardiovascular Center, Harapan Kita, Jakarta, Indonesia; Hoshide, S., Division of Cardiovascular Medicine, Department of Medicine, Jichi Medical University School of Medicine, Tochigi, Japan; Tay, J.C., Department of General Medicine, Tan Tock Seng Hospital, Singapore, Singapore; Prasad Sogunuru, G., MIOT International Hospital, Chennai, India, College of Medical Sciences, Kathmandu University, Bharatpur, Nepal; Zhang, Y., Divisions of Hypertension and Heart Failure, Fu Wai Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China; Verma, N., Department of Physiology, King George's Medical University, Lucknow, India; Wang, T.-D., Cardiovascular Center and Division of Cardiology, Department of Internal Medicine, National Taiwan University Hospital and National Taiwan University College of Medicine, Taipei City, Taiwan; Kario, K., Division of Cardiovascular Medicine, Department of Medicine, Jichi Medical University School of Medicine, Tochigi, Japan; the HOPE Asia Network |
Stroke is the primary cause of disability and vascular death worldwide, including Asia. Asian characteristics that differ from the West lead to higher stroke incidence. Stroke epidemiology studies in Asia have shown varying levels of mortality, incidence, prevalence, and burden of disease. Hypertension is the most prevalent risk factor found in Asia. Besides ethnicity that is associated with stroke incidence, both systolic blood pressure, diastolic blood pressure, and blood pressure variability are positively correlated with stroke incidence. Post-stroke cognitive impairment is one of the sequelae that affect one-third of stroke survivors and has become a significant public health concern that is often neglected despite its increasing prevalence. Therefore, it is very important to prevent recurrence by treating stroke optimally and effectively. Increasing awareness and treatment adherence to hypertension, the leading risk factor for stroke, became the main goal in several countries in Asia. © 2020 The Authors. The Journal of Clinical Hypertension published by Wiley Periodicals LLC. |
Asia; hypertension; stroke |
Asia; awareness; blood pressure variability; cerebrovascular accident; clinical effectiveness; dementia; diastolic blood pressure; disease burden; global health; human; hypertension; incidence; medication compliance; mortality rate; post stroke dementia; prevalence; recurrent disease; Review; risk factor; systolic blood pressure; blood pressure; cerebrovascular accident; hypertension; Asia; Blood Pressure; Humans; Hypertension; Incidence; Risk Factors; Stroke |
John Wiley and Sons Inc |
15246175 |
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33190399 |
Review |
Q2 |
909 |
5078 |
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582 |
Scheffler C., Hermanussen M., Soegianto S.D.P., Homalessy A.V., Touw S.Y., Angi S.I., Ariyani Q.S., Suryanto T., Matulessy G.K.I., Fransiskus T., Safira A.V.C., Puteri M.N., Rahmani R., Ndaparoka D.N., Payong M.K.E., Indrajati Y.D., Purba R.K.H., Manubulu R.M., Julia M., Pulungan A.B. |
22836040300;7005909056;57212268744;57209200014;57209199756;57221800920;57221801196;57221800170;57221808632;57221804338;57221806887;57221809375;57221807473;57221800477;57209199238;57221808668;57221803203;57221808341;14019743100;57192905981; |
Stunting as a synonym of social disadvantage and poor parental education |
2021 |
International Journal of Environmental Research and Public Health |
18 |
3 |
1350 |
1 |
13 |
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5 |
https://www.scopus.com/inward/record.uri?eid=2-s2.0-85100239177&doi=10.3390%2fijerph18031350&partnerID=40&md5=33700577101c6821f63520cfa18f471d |
Institute of Biochemistry and Biology, Human Biology, University of Potsdam, Potsdam, 14469, Germany; University of Kiel, Aschauhof, Eckernförde-Altenhof, 24340, Germany; Indonesian Pediatric Society, East Nusa Tenggara Branch, Kupang-East Nusa Tenggara, Kupang, 85351, Indonesia; Indonesian Medical Association Branch, Kupang, 85351, Indonesia; DDS PPDGS Konservasi Gigi FKG UGM, Jl. Sekip Utara, Sumatra, Medan, 20153, Indonesia; Faculty of Medicine, Nusa Cendana University, Kupang, 85351, Indonesia; Department of Child Health, Faculty of Medicine, Public Health and Nursing, Universitas Gadjah Mada-Dr, Sardjito General Hospital, Yogyakarta, 55281, Indonesia; Department of Child Health, Faculty of Medicine, Universitas Indonesia-Ciptomangunkusumo Hospital, Jakarta, 10430, Indonesia |
Scheffler, C., Institute of Biochemistry and Biology, Human Biology, University of Potsdam, Potsdam, 14469, Germany; Hermanussen, M., University of Kiel, Aschauhof, Eckernförde-Altenhof, 24340, Germany; Soegianto, S.D.P., Indonesian Pediatric Society, East Nusa Tenggara Branch, Kupang-East Nusa Tenggara, Kupang, 85351, Indonesia; Homalessy, A.V., Indonesian Medical Association Branch, Kupang, 85351, Indonesia; Touw, S.Y., Indonesian Medical Association Branch, Kupang, 85351, Indonesia; Angi, S.I., DDS PPDGS Konservasi Gigi FKG UGM, Jl. Sekip Utara, Sumatra, Medan, 20153, Indonesia; Ariyani, Q.S., Indonesian Medical Association Branch, Kupang, 85351, Indonesia; Suryanto, T., Indonesian Pediatric Society, East Nusa Tenggara Branch, Kupang-East Nusa Tenggara, Kupang, 85351, Indonesia; Matulessy, G.K.I., Indonesian Medical Association Branch, Kupang, 85351, Indonesia; Fransiskus, T., Indonesian Pediatric Society, East Nusa Tenggara Branch, Kupang-East Nusa Tenggara, Kupang, 85351, Indonesia; Safira, A.V.C., Indonesian Medical Association Branch, Kupang, 85351, Indonesia; Puteri, M.N., Indonesian Medical Association Branch, Kupang, 85351, Indonesia; Rahmani, R., Indonesian Medical Association Branch, Kupang, 85351, Indonesia; Ndaparoka, D.N., Indonesian Medical Association Branch, Kupang, 85351, Indonesia; Payong, M.K.E., Indonesian Medical Association Branch, Kupang, 85351, Indonesia; Indrajati, Y.D., DDS PPDGS Konservasi Gigi FKG UGM, Jl. Sekip Utara, Sumatra, Medan, 20153, Indonesia; Purba, R.K.H., Faculty of Medicine, Nusa Cendana University, Kupang, 85351, Indonesia; Manubulu, R.M., Indonesian Pediatric Society, East Nusa Tenggara Branch, Kupang-East Nusa Tenggara, Kupang, 85351, Indonesia; Julia, M., Department of Child Health, Faculty of Medicine, Public Health and Nursing, Universitas Gadjah Mada-Dr, Sardjito General Hospital, Yogyakarta, 55281, Indonesia; Pulungan, A.B., Department of Child Health, Faculty of Medicine, Universitas Indonesia-Ciptomangunkusumo Hospital, Jakarta, 10430, Indonesia |
Socially, economically, politically and emotionally (SEPE) disadvantaged children are shorter than children from affluent background. In view of previous work on the lack of association between nutrition and child growth, we performed a study in urban schoolchildren. We measured 723 children (5.83 to 13.83 years); Kupang, Indonesia; three schools with different social back-ground. We investigated anthropometric data, clinical signs of malnutrition, physical fitness, parental education, and household equipment. Subjective self-confidence was assessed by the MacArthur test. The prevalence of stunting was between 8.5% and 46.8%. Clinical signs of under-or malnutrition were absent even in the most underprivileged children. There was no delay in tooth erup-tion. Underprivileged children are physically fitter than the wealthy. The correlation between height and state of nutrition (BMI_SDS, skinfold_SDS, MUAC_SDS) ranged between r = 0.69 (p < 0.01) and r = 0.43 (p < 0.01) in private school children, and between r = 0.07 (ns) and r = 0.32 (p < 0.01) in the underprivileged children. Maternal education interacted with height in affluent (r = 0.20, p < 0.01) and in underprivileged children (r = 0.20, p < 0.01). The shortness of SEPE disadvantaged children was not associated with anthropometric and clinical signs of malnutrition, nor with delay in physical development. Stunting is a complex phenomenon and may be considered a synonym of social disadvantage and poor parental education. © 2021 by the authors. Licensee MDPI, Basel, Switzerland. |
Economic; Political and emotional factors on growth; Social; Stunting |
child; cross-sectional study; growth disorder; human; Indonesia; malnutrition; nutritional status; prevalence; Child; Cross-Sectional Studies; Growth Disorders; Humans; Indonesia; Malnutrition; Nutritional Status; Prevalence |
MDPI AG |
16617827 |
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33540885 |
Article |
Q2 |
747 |
6560 |
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602 |
Yusuf P.A., Hubka P., Tillein J., Vinck M., Kral A. |
57192156597;6506008977;6602884109;35338597200;55668482500; |
Deafness Weakens Interareal Couplings in the Auditory Cortex |
2021 |
Frontiers in Neuroscience |
14 |
|
625721 |
|
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5 |
https://www.scopus.com/inward/record.uri?eid=2-s2.0-85100543064&doi=10.3389%2ffnins.2020.625721&partnerID=40&md5=a896b3ce6070ccfa904918c9e995ca32 |
Department of Medical Physics/Medical Technology Core Cluster IMERI, Faculty of Medicine, University of Indonesia, Jakarta, Indonesia; Institute of AudioNeuroTechnology, Hannover Medical School, Hanover, Germany; Department of Experimental Otology of the ENT Clinics, Hannover Medical School, Hanover, Germany; Department of Otorhinolaryngology, Goethe University, Frankfurt am Main, Germany; MedEL Company, Innsbruck, Austria; Ernst Strüngmann Institut for Neuroscience in Cooperation with Max Planck Society, Frankfurt, Germany; Donders Centre for Neuroscience, Radboud University, Department of Neuroinformatics, Nijmegen, Netherlands; Department of Biomedical Sciences, School of Medicine and Health Sciences, Macquarie University, Sydney, NSW, Australia |
Yusuf, P.A., Department of Medical Physics/Medical Technology Core Cluster IMERI, Faculty of Medicine, University of Indonesia, Jakarta, Indonesia, Institute of AudioNeuroTechnology, Hannover Medical School, Hanover, Germany, Department of Experimental Otology of the ENT Clinics, Hannover Medical School, Hanover, Germany; Hubka, P., Institute of AudioNeuroTechnology, Hannover Medical School, Hanover, Germany, Department of Experimental Otology of the ENT Clinics, Hannover Medical School, Hanover, Germany; Tillein, J., Institute of AudioNeuroTechnology, Hannover Medical School, Hanover, Germany, Department of Experimental Otology of the ENT Clinics, Hannover Medical School, Hanover, Germany, Department of Otorhinolaryngology, Goethe University, Frankfurt am Main, Germany, MedEL Company, Innsbruck, Austria; Vinck, M., Ernst Strüngmann Institut for Neuroscience in Cooperation with Max Planck Society, Frankfurt, Germany, Donders Centre for Neuroscience, Radboud University, Department of Neuroinformatics, Nijmegen, Netherlands; Kral, A., Institute of AudioNeuroTechnology, Hannover Medical School, Hanover, Germany, Department of Experimental Otology of the ENT Clinics, Hannover Medical School, Hanover, Germany, Department of Biomedical Sciences, School of Medicine and Health Sciences, Macquarie University, Sydney, NSW, Australia |
The function of the cerebral cortex essentially depends on the ability to form functional assemblies across different cortical areas serving different functions. Here we investigated how developmental hearing experience affects functional and effective interareal connectivity in the auditory cortex in an animal model with years-long and complete auditory deprivation (deafness) from birth, the congenitally deaf cat (CDC). Using intracortical multielectrode arrays, neuronal activity of adult hearing controls and CDCs was registered in the primary auditory cortex and the secondary posterior auditory field (PAF). Ongoing activity as well as responses to acoustic stimulation (in adult hearing controls) and electric stimulation applied via cochlear implants (in adult hearing controls and CDCs) were analyzed. As functional connectivity measures pairwise phase consistency and Granger causality were used. While the number of coupled sites was nearly identical between controls and CDCs, a reduced coupling strength between the primary and the higher order field was found in CDCs under auditory stimulation. Such stimulus-related decoupling was particularly pronounced in the alpha band and in top–down direction. Ongoing connectivity did not show such a decoupling. These findings suggest that developmental experience is essential for functional interareal interactions during sensory processing. The outcomes demonstrate that corticocortical couplings, particularly top-down connectivity, are compromised following congenital sensory deprivation. © Copyright © 2021 Yusuf, Hubka, Tillein, Vinck and Kral. |
bottom-up; cochlear implant; congenital deafness; predictive coding; synchronization; top–down |
adult; alpha rhythm; animal experiment; animal model; animal tissue; Article; auditory cortex; auditory stimulation; beta rhythm; cochlea; controlled study; functional connectivity; hearing acuity; hearing impairment; local field potential; nonhuman |
Frontiers Media S.A. |
16624548 |
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Article |
Q2 |
1499 |
2279 |
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794 |
Subali A.D., Wiyono L. |
57222071247;57207889054; |
Reverse Transcriptase Loop Mediated Isothermal Amplification (RT-LAMP) for COVID-19 diagnosis: a systematic review and meta-analysis |
2021 |
Pathogens and Global Health |
115 |
5 |
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281 |
291 |
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5 |
https://www.scopus.com/inward/record.uri?eid=2-s2.0-85107466709&doi=10.1080%2f20477724.2021.1933335&partnerID=40&md5=bc2cfc39928d141c8b322792377bdf60 |
Faculty of Medicine, Universitas Brawijaya, Malang, East Java, Indonesia; Faculty of Medicine, Universitas Indonesia - Cipto Mangunkusumo Hospital, Jakarta, Indonesia |
Subali, A.D., Faculty of Medicine, Universitas Brawijaya, Malang, East Java, Indonesia, Faculty of Medicine, Universitas Indonesia - Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Wiyono, L., Faculty of Medicine, Universitas Brawijaya, Malang, East Java, Indonesia, Faculty of Medicine, Universitas Indonesia - Cipto Mangunkusumo Hospital, Jakarta, Indonesia |
COVID-19 pandemic has become a global public health priority. The rapid increase in infection numbers, along with a significant number of deaths, has made the virus a serious threat to human health. Rapid, reliable, and simple diagnostic methods are critical to controlling the disease. While Reverse Transcriptase Polymerase Chain Reaction (RT-PCR) is the current diagnostic gold standard, Reverse Transcriptase Loop-Mediated Isothermal Amplification (RT-LAMP) appears to be a compelling alternative diagnostic test due to its greater simplicity, shorter time to obtain a result, and lower cost. This study examined RT-LAMP application for rapid identification of SARS-CoV-2 infection compared to the RT-PCR assay. A systematic review and meta-analysis was conducted over six scientific databases in accordance with PRISMA guidelines. Original studies published in English conducted on human clinical samples were included. Articles evaluating the sensitivity and specificity of RT-LAMP relative to RT-PCR were considered eligible. Quality assessment of bias and applicability was examined based on QUADAS-2. A total of 351 studies were found based on the keywords and search queries. Fourteen eligible case–control studies fit the mentioned criteria. Quality assessment using QUADAS-2 indicated alow risk of bias for all included studies. All case studies, containing 2,112 samples, had acumulative sensitivity of 95.5% (CI 97.5% = 90.8–97.9%) and cumulative specificity of 99.5% (CI 97.5% = 97.7–99.9%). The RT-LAMP assay could be areliable alternative COVID-19 diagnostic method due to its reduced cost and processing time compared to RT-PCR. RT-LAMP could potentially be utilized during critical high-throughput and high-demand situations. © 2021 Informa UK Limited, trading as Taylor & Francis Group. |
COVID-19; diagnostic test; RT-LAMP; RT-PCR; SARS-CoV-2 |
coronavirus RNA dependent RNA polymerase; coronavirus spike glycoprotein; envelope protein; nonstructural protein 3; nucleocapsid protein; RNA directed DNA polymerase; virus RNA; coronavirus disease 2019; diagnostic test accuracy study; human; limit of detection; meta analysis; nasopharyngeal swab; open reading frame; practice guideline; receiver operating characteristic; reverse transcription loop mediated isothermal amplification; reverse transcription polymerase chain reaction; Review; sensitivity and specificity; Severe acute respiratory syndrome coronavirus 2; systematic review; virus gene; genetics; molecular diagnosis; nucleic acid amplification; pandemic; COVID-19; Humans; Molecular Diagnostic Techniques; Nucleic Acid Amplification Techniques; Pandemics; Reverse Transcriptase Polym |
Taylor and Francis Ltd. |
20477724 |
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34086539 |
Review |
Q1 |
945 |
4761 |
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859 |
Gunardi W.D., Karuniawati A., Umbas R., Bardosono S., Lydia A., Soebandrio A., Safari D. |
57222314683;54886816200;6602634832;21933841000;8451287200;8602893200;23493586700; |
Biofilm-Producing Bacteria and Risk Factors (Gender and Duration of Catheterization) Characterized as Catheter-Associated Biofilm Formation |
2021 |
International Journal of Microbiology |
2021 |
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8869275 |
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5 |
https://www.scopus.com/inward/record.uri?eid=2-s2.0-85102259916&doi=10.1155%2f2021%2f8869275&partnerID=40&md5=2173f2f0a162e1277f45979d11bf433c |
Department of Clinical Microbiology, Faculty of Medicine, Krida Wacana Christian University, Jakarta, 1151, Indonesia; Department of Clinical Microbiology, Faculty of Medicine, Universitas Indonesia, Jakarta, 10320, Indonesia; Department of Urology, FMUI-CMH, Jakarta, 10430, Indonesia; Department of Nutrition, Faculty of Medicine, Universitas Indonesia, Jakarta, 10430, Indonesia; Department of Internal Medicine, Faculty of Medicine, Universitas Indonesia, Jakarta, 10430, Indonesia; Eijkman Institute for Molecular Biology, Jakarta, 10430, Indonesia |
Gunardi, W.D., Department of Clinical Microbiology, Faculty of Medicine, Krida Wacana Christian University, Jakarta, 1151, Indonesia; Karuniawati, A., Department of Clinical Microbiology, Faculty of Medicine, Universitas Indonesia, Jakarta, 10320, Indonesia; Umbas, R., Department of Urology, FMUI-CMH, Jakarta, 10430, Indonesia; Bardosono, S., Department of Nutrition, Faculty of Medicine, Universitas Indonesia, Jakarta, 10430, Indonesia; Lydia, A., Department of Internal Medicine, Faculty of Medicine, Universitas Indonesia, Jakarta, 10430, Indonesia; Soebandrio, A., Eijkman Institute for Molecular Biology, Jakarta, 10430, Indonesia; Safari, D., Eijkman Institute for Molecular Biology, Jakarta, 10430, Indonesia |
Background. A catheter-associated urinary tract infection (CA-UTI) is preceded by biofilm formation, which is related to several risk factors such as gender, age, diabetic status, duration of catheterization, bacteriuria before catheterization, virulence gene factor, and antibiotic usage. Aims. This study aims to identify the microbial composition of catheter samples, including its corresponding comparison with urine samples, to determine the most important risk factors of biofilm formation and characterize the virulence gene factors that correlate with biofilm formation. Methods. A longitudinal cross-sectional study was conducted on 109 catheterized patients from September 2017 to January 2018. The risk factors were obtained from the patients' medical records. All catheter and urine samples were cultured after removal, followed by biomass quantification. Isolate identification and antimicrobial susceptibility testing were performed using the Vitex2 system. Biofilm-producing bacteria were identified by the Congo Red Agar (CRA) method. A PCR test characterized the virulence genes of dominant bacteria (E. coli). All data were collected and processed for statistical analysis. Results. Out of 109 catheterized patients, 78% of the catheters were culture positive, which was higher than those of the urine samples (37.62%). The most common species isolated from the catheter cultures were Escherichia coli (28.1%), Candida sp. (17.8%), Klebsiella pneumoniae (15.9%), and Enterococcus faecalis (13.1%). E. coli (83.3%) and E. faecalis (78.6%) were the main isolates with a positive CRA. A statistical analysis showed that gender and duration prior to catheterization were associated with an increased risk of biofilm formation p<0.05. Conclusion. E. coli and E. faecalis were the most common biofilm-producing bacteria isolated from the urinary catheter. Gender and duration are two risk factors associated with biofilm formation, therefore determining the risk of CAUTI. The presence of PapC as a virulence gene encoding pili correlates with the biofilm formation. Biofilm-producing bacteria, female gender, duration of catheterization (more than five days), and PapC gene presence have strong correlation with the biofilm formation. To prevent CAUTI, patients with risk factors should be monitored by urinalysis tests to detect earlier the risk of biofilm formation. © 2021 Wani Devita Gunardi et al. |
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Hindawi Limited |
1687918X |
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Article |
Q3 |
696 |
7161 |
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897 |
Oshima T., Siah K.T.H., Kim Y.S., Patcharatrakul T., Chen C.-L., Mahadeva S., Park H., Chen M.-H., Lu C.-L., Hou X., Quach D.T., Syam A.F., Rahman M.M., Xiao Y., Jinsong L., Chua A.S.B., Miwa H. |
7401663152;35757936600;57196171210;8549899200;23495616400;6602694336;56255219600;57216452428;7404805612;57210061408;37099075800;8443384400;57216556340;23500436000;57221693058;7004518894;56921458500; |
Knowledge, attitude, and practice survey of gastroparesis in asia by asian neurogastroenterology and motility association |
2021 |
Journal of Neurogastroenterology and Motility |
27 |
1 |
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46 |
54 |
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5 |
https://www.scopus.com/inward/record.uri?eid=2-s2.0-85099728456&doi=10.5056%2fJNM20117&partnerID=40&md5=49d79381fdad1a0dca816161fd54b8e0 |
Division of Gastroenterology and Hepatology, Department of Internal Medicine, Hyogo College of Medicine, Nishinomiya, Hyogo, Japan; Department of Medicine, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore; Division of Gastroenterology and Hepatology, Department of Medicine, National University Hospital, Singapore, Singapore; Digestive Disease Research Institute, School of Medicine, Wonkwang University, Iksan, Jeollabuk-do, South Korea; Center of Excellence in Neurogastroenterology and Motility, Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand; Division of Gastroenterology, Department of Medicine, King Chulalongkorn Memorial Hospital, Thai Red Cross Society, Bangkok, Thailand; Department of Medicine, Hualien Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation, Tzu Chi University, Hualien, Taiwan; Institute of Medical Sciences, College of Medicine, Tzu Chi University, Hualien, Taiwan; Department of Medicine, University of Malaya, Kuala Lumpur, Malaysia; Department of Internal Medicine, Gangnam Severance Hospital, Yonsei University, Seoul, South Korea; Department of Gastroenterology and Hepatology, First Affiliated Hospital, Sun Yat-sen University, Guangzhou, China; Endoscopy Center for Diagnosis and Treatment, Taipei Veterans General Hospital, Taipei, Taiwan; Division of Gastroenterology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China; Department of Internal Medicine, University of Medicine and Pharmacy at Ho Chi Minh City, Ho Chi Minh, Viet Nam; Division of Gastroenterology, Department of Internal Medicine, Faculty of Medicine, Universitas Indonesia, Cipto Mangunkusumo Hospital, Jakarta Pusat, Indonesia; Department of Gastroenterology, Sheikh Russel National Gastroliver Institute and Hospital, Dhaka, Bangladesh; Gastro Center Ipoh, Ipoh, Malaysia |
Oshima, T., Division of Gastroenterology and Hepatology, Department of Internal Medicine, Hyogo College of Medicine, Nishinomiya, Hyogo, Japan; Siah, K.T.H., Department of Medicine, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore, Division of Gastroenterology and Hepatology, Department of Medicine, National University Hospital, Singapore, Singapore; Kim, Y.S., Digestive Disease Research Institute, School of Medicine, Wonkwang University, Iksan, Jeollabuk-do, South Korea; Patcharatrakul, T., Center of Excellence in Neurogastroenterology and Motility, Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand, Division of Gastroenterology, Department of Medicine, King Chulalongkorn Memorial Hospital, Thai Red Cross Society, Bangkok, Thailand; Chen, C.-L., Department of Medicine, Hualien Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation, Tzu Chi University, Hualien, Taiwan, Institute of Medical Sciences, College of Medicine, Tzu Chi University, Hualien, Taiwan; Mahadeva, S., Department of Medicine, University of Malaya, Kuala Lumpur, Malaysia; Park, H., Department of Internal Medicine, Gangnam Severance Hospital, Yonsei University, Seoul, South Korea; Chen, M.-H., Department of Gastroenterology and Hepatology, First Affiliated Hospital, Sun Yat-sen University, Guangzhou, China; Lu, C.-L., Endoscopy Center for Diagnosis and Treatment, Taipei Veterans General Hospital, Taipei, Taiwan; Hou, X., Division of Gastroenterology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China; Quach, D.T., Department of Internal Medicine, University of Medicine and Pharmacy at Ho Chi Minh City, Ho Chi Minh, Viet Nam; Syam, A.F., Division of Gastroenterology, Department of Internal Medicine, Faculty of Medicine, Universitas Indonesia, Cipto Mangunkusumo Hospital, Jakarta Pusat, Indonesia; Rahman, M.M., Department of Gastroenterology, Sheikh Russel National Gastroliver Institute and Hospital, Dhaka, Bangladesh; Xiao, Y., Department of Gastroenterology and Hepatology, First Affiliated Hospital, Sun Yat-sen University, Guangzhou, China; Jinsong, L., Division of Gastroenterology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China; Chua, A.S.B., Gastro Center Ipoh, Ipoh, Malaysia; Miwa, H., Division of Gastroenterology and Hepatology, Department of Internal Medicine, Hyogo College of Medicine, Nishinomiya, Hyogo, Japan |
Background/Aims Gastroparesis is identified as a subject that is understudied in Asia. The scientific committee of the Asian Neurogastroenterology and Motility Association performed a Knowledge, Attitude, and Practices survey on gastroparesis among doctors in Asia. Methods The questionnaire was created and developed through a literature review of current gastroparesis works of literature by the scientific committee of Asian Neurogastroenterology and Motility Association. Results A total of 490 doctors from across Asia (including Bangladesh, China, Hong Kong, Indonesia, Japan, Malaysia, Myanmar, the Philippines, Singapore, South Korea, Taiwan, Thailand, and Vietnam) participated in the survey. Gastroparesis is a significant gastrointestinal condition. However, a substantial proportion of respondents was unable to give the correct definition and accurate diagnostic test. The main reason for lack of interest in diagnosing gastroparesis was "the lack of reliable diagnostic tests"(46.8%) or "a lack of effective treatment"(41.5%). Only 41.7% of respondents had access to gastric emptying scintigraphy. Most doctors had never diagnosed gastroparesis at all (25.2%) or diagnosed fewer than 5 patients a year (52.1%). Conclusions Gastroparesis can be challenging to diagnose due to the lack of instrument, standardized method, and paucity of research data on normative value, risk factors, and treatment studies in Asian patients. Future strategies should concentrate on how to disseminate the latest knowledge of gastroparesis in Asia. In particular, there is an urgent need to estimate the magnitude of the problems in high risk and idiopathic patients as well as a standardized diagnostic procedure in Asia. © 2021 The Korean Society of Neurogastroenterology and Motility. |
Asia; Dyspepsia; Gastroparesis; Health care surveys; Health education |
Article; Asia; Bangladesh; China; demography; diagnostic test; female; Hong Kong; human; Indonesia; Japan; knowledge; Malaysia; male; medical society; Myanmar; Philippines; physician attitude; questionnaire; scintigraphy; Singapore; South Korea; stomach emptying; stomach paresis; Taiwan; test meal; Thailand; Viet Nam |
Korean Society of Neurogastroenterology and Motility |
20930879 |
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Article |
Q1 |
1345 |
2715 |
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