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Id	Authors	Author S Id	Title	Year	Source Title	Volume	Issue	Art No	Page Start	Page End	Cited By	Link	Affiliations	Authors With Affiliations	Abstract	Author Keywords	Index Keywords	Publisher	Issn	Pubmed Id	Document Type	Sjr Best Quartile	Sjr	Sjr Rank
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789	Rhatomy S., Dilogo I.H.	57204509883;56161962800;	Core decompression and biological treatment in osteonecrosis of the hip due to systemic lupus erythematosus, 8-year follow-up: A case report	2021	Open Access Macedonian Journal of Medical Sciences	9			74	79		https://www.scopus.com/inward/record.uri?eid=2-s2.0-85107632892&doi=10.3889%2foamjms.2021.5798&partnerID=40&md5=d126812c5dab6196ca3a6f0a5513b86a	Department of Orthopaedic and Traumatology, Faculty of Medicine, Public Health and Nursing, Universitas Gadjah Mada, Dr. Soeradji Tirtonegoro General Hospital, Yogyakarta, Indonesia; Department of Orthopaedic and Traumatology, Dr. Cipto Mangunkusumo National Hospital, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia	Rhatomy, S., Department of Orthopaedic and Traumatology, Faculty of Medicine, Public Health and Nursing, Universitas Gadjah Mada, Dr. Soeradji Tirtonegoro General Hospital, Yogyakarta, Indonesia; Dilogo, I.H., Department of Orthopaedic and Traumatology, Dr. Cipto Mangunkusumo National Hospital, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia	BACKGROUND: Osteonecrosis most commonly affects the femoral head, especially in middle-aged adults. It can be caused by trauma, chronic inflammation, or infection. It leads to collapse of the entire femoral head and culminates with total hip replacement. CASE REPORT: A 29-year-old female with systemic lupus erythematosus (SLE) had a chief complaint of bilateral hip pain. She was diagnosed with early osteonecrosis of the femoral head (FICAT stage II) using magnetic resonance imaging and core decompression surgery was performed using three small diameter (4 mm) drillings and added biological treatment. She was evaluated with a visual analog scale (VAS), Harris hip score (HHS), and plain radiography in the pre-operative stage and post-operative follow-up. RESULTS: Functional outcome at 8-year follow-up showed improvement with significantly decreased VAS (pre-operative: 5, post-operative: 0), significant improvement of HHS from 52.725 points (poor) pre-operative to 92.025 points (excellent) post-operative, and subsided femoral head lesion. CONCLUSIONS: Surgical decompression and biological treatment result in decreased intraosseous pressure and enhanced osteogenesis. It can restrict the SLE disease progression and limit the number of cell death. © 2021 Sholahuddin Rhatomy, Ismail Hadisoebroto Dilogo.	Avascular necrosis; Core decompression; Hip; Osteonecrosis; Systemic lupus erythematosus	corticosteroid; adult; antalgic lump; arteriovenous shunt; Article; avascular necrosis; bone development; bone graft; bone necrosis; bone radiography; case report; clinical article; clinical examination; daily life activity; decompression surgery; differential diagnosis; disease exacerbation; female; femoral head; fluoroscopy; follow up; functional outcome; Harris hip score; hip osteoarthritis; hip pain; hip replacement; human; intermittent pain; morphogenesis; nuclear magnetic resonance imaging; ossification; osteogenesis imperfecta; physical examination; preoperative evaluation; range of motion; systemic lupus erythematosus; thigh region; visual analog scale; weight bearing	Scientific Foundation SPIROSKI	18579655		Article	Q3	288	15252	View
793	Sitohang I.B.S., Nelson B., Marissa M., Indriatmi W., Wisnu W.	56734569200;57222619613;57210795916;57189888041;57200425452;	Evaluation of modified melasma area and severity index in hyperthyroid patients receiving anti-thyroid drugs	2021	Open Access Macedonian Journal of Medical Sciences	9	B		344	349		https://www.scopus.com/inward/record.uri?eid=2-s2.0-85107477787&doi=10.3889%2foamjms.2021.6082&partnerID=40&md5=ecf1548d04f6591bb645bfc03792883e	Department of Dermatology and Venereology, Faculty of Medicine, Universitas Indonesia, Dr. Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Department of Internal Medicine, Metabolic Endocrine Division, Faculty of Medicine, Universitas Indonesia, Dr. Cipto Mangunkusumo Hospital, Jakarta, Indonesia	Sitohang, I.B.S., Department of Dermatology and Venereology, Faculty of Medicine, Universitas Indonesia, Dr. Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Nelson, B., Department of Dermatology and Venereology, Faculty of Medicine, Universitas Indonesia, Dr. Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Marissa, M., Department of Dermatology and Venereology, Faculty of Medicine, Universitas Indonesia, Dr. Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Indriatmi, W., Department of Dermatology and Venereology, Faculty of Medicine, Universitas Indonesia, Dr. Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Wisnu, W., Department of Internal Medicine, Metabolic Endocrine Division, Faculty of Medicine, Universitas Indonesia, Dr. Cipto Mangunkusumo Hospital, Jakarta, Indonesia	BACKGROUND: Melasma is a common hyperpigmentation disorder, which causes brownish discoloration of the face. Despite unclear mechanisms, thyroid hormones were thought to play a role in melasma. AIM: This study aims to determine and compare the clinical improvement of melasma in hyperthyroid patients receiving anti-thyroid drugs. METHODS: An interventional study with a quasi-experimental design (pre-post-intervention study) was conducted at the Internal Medicine Outpatient Clinic and Dermatology and Venereology Outpatient Clinic, Cipto Mangunkusumo Hospital, Jakarta, Indonesia, from July 2019 to March 2020. A comparative analysis was done to compare the modified melasma area and severity index (mMASI) in hyperthyroid patients before and after 12 weeks of anti-thyroid drugs. All subjects did not receive any additional topical therapies for their melasma. The clinical features were evaluated objectively at baseline and 12th-week visit, by mMASI score on different areas of the face (forehead, left-right malar, and chin) and Wood’s lamp examination. RESULTS: All areas showed a decline in mMASI score components (e.g., involvement areas and darkness degree) after 12 weeks of treatment. However, only the malar area showed a significant decline (p < 0.05). Wood’s lamp examination at baseline revealed dermal type melasma on 17 subjects, mixed type on six subjects, and epidermal type on one subject. All types remained unchanged after 12 weeks of treatment. CONCLUSIONS: Our study demonstrated that mMASI score in malar area improved significantly, this might be because malar area included this study were comprised of epidermal, dermal, and mixed type. On the other hand, based on Wood’s lamp examination, all types of melasma remained unchanged after 12 weeks of treatment. © 2021 Irma Bernadette S. Sitohang, Benny Nelson, Melani Marissa, Wresti Indriatmi, Wismandari Wisnu.	Hyperthyroid; Melasma; Modified melasma area and severity index; Wood’s lamp	amiodarone; antithyroid agent; octreotide; thiamazole; thyroid hormone; adult; Article; chloasma; clinical article; clinical assessment; clinical feature; dermatology; experimental design; female; follow up; forehead; human; hyperpigmentation; hyperthyroidism; intervention study; male; observational study; outpatient department; prospective study; thyroid disease; thyroid function test; topical treatment; visual analog scale	Scientific Foundation SPIROSKI	18579655		Article	Q3	288	15252	View
796	Pontoh L.A.P., Ismail H.D., Fiolin J., Yausep O.E.	57192907426;57224810749;57194498274;57200086151;	Pain following single-bundle versus double-bundle anterior cruciate ligament reconstruction: A systematic review	2021	Open Access Macedonian Journal of Medical Sciences	9			153	162		https://www.scopus.com/inward/record.uri?eid=2-s2.0-85107326267&doi=10.3889%2foamjms.2021.5995&partnerID=40&md5=907e110a1eb993238ca4374c25cdcb6a	Department of Orthopaedic and Traumatology, Faculty of Medicine, Universitas Indonesia, Fatmawati General Hospital, Jakarta, Indonesia; Department of Orthopaedics and Traumatology, Faculty of Medicine, Universitas Indonesia, Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Jakarta Knee Orthopaedic Sports Center, Pondok Indah Hospital, Jakarta, Indonesia; Faculty of Medicine, Universitas Indonesia, Cipto Mangunkusumo Hospital, Jakarta, Indonesia	Pontoh, L.A.P., Department of Orthopaedic and Traumatology, Faculty of Medicine, Universitas Indonesia, Fatmawati General Hospital, Jakarta, Indonesia; Ismail, H.D., Department of Orthopaedics and Traumatology, Faculty of Medicine, Universitas Indonesia, Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Fiolin, J., Jakarta Knee Orthopaedic Sports Center, Pondok Indah Hospital, Jakarta, Indonesia; Yausep, O.E., Faculty of Medicine, Universitas Indonesia, Cipto Mangunkusumo Hospital, Jakarta, Indonesia	BACKGROUND: Double-bundle (DB) anterior cruciate ligament reconstruction (ACLR) has been known to result in better functional outcomes, joint stability, and lower revision rates compared to single-bundle (SB) ACLR. However, given the increased invasiveness and damage to the surrounding tissue area, it is proposed that it may be associated with increased pain. AIM: This review aims to gather all studies and literature that reported pain as an outcome when comparing SB versus DB ACLR. METHODS: Literature searching was conducted across seven search engines for studies reporting pain as an outcome and comparing SB versus DB ACLR. RESULTS: Eight studies met the eligibility criteria and were included in the study. Overall, the studies show variable findings regarding pain in DB compared to SB ACLR, with the only statistically significant results from two studies indicating that DB ACLR is associated with more pain than SB ACLR. CONCLUSION: Based on the limited evidence available, no conclusions can be made regarding the pain experienced between people receiving either procedure. This constitutes a need for additional studies with increased follow-up time periods, larger sample size, and better study design. © 2021 Ludwig A. P. Pontoh, H. D. Ismail, Jessica Fiolin, Oliver Emmanuel Yausep.	Anterior cruciate ligament; Double bundle; Pain; Reconstruction; Single bundle	analgesic agent; anesthetic agent; anesthesia; anterior cruciate ligament injury; anterior cruciate ligament reconstruction; collateral ligament; data analysis; data extraction; follow up; gracilis flap; hamstring muscle; hamstring tendon; human; joint stability; knee ligament; knee meniscus rupture; knee pain; ligament surgery; meta analysis; operation duration; pain; randomized controlled trial (topic); Review; systematic review; tendon graft; visual analog scale	Scientific Foundation SPIROSKI	18579655		Review	Q3	288	15252	View
876	Sari I.P., Audindra S., Zhafira A.S., Rahma A.A., Syarira C.V., Wahdini S.	57197543698;57222006228;57205515532;57222005612;57222010715;57203684068;	Nutritional status of school-aged children with intestinal parasite infection in South Jakarta, Indonesia	2021	Open Access Macedonian Journal of Medical Sciences	9	E		95	100	3	https://www.scopus.com/inward/record.uri?eid=2-s2.0-85100938719&doi=10.3889%2foamjms.2021.5711&partnerID=40&md5=1772780d39afba8ba66dd65e8997f0b4	Department of Parasitology, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Undergraduate Program in Medical Doctor, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia	Sari, I.P., Department of Parasitology, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Audindra, S., Undergraduate Program in Medical Doctor, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Zhafira, A.S., Undergraduate Program in Medical Doctor, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Rahma, A.A., Undergraduate Program in Medical Doctor, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Syarira, C.V., Undergraduate Program in Medical Doctor, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Wahdini, S., Department of Parasitology, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia	BACKGROUND: The prevalence of intestinal parasitic infection still high in Indonesia and lead to nutritional disorder, especially in the school-aged children. AIM: This research conducted to find the association of intestinal parasitic infection to the nutritional status of the children. METHODS: This was a cross sectional study, conducted in January 2016 in one primary school in South Jakarta, Jakarta, Indonesia, by collecting the children’s stool from 1st to 5th grade. Direct examination of the stool was conducted in the Parasitology Department, Faculty of Medicine, Universitas Indonesia, by Lugol and eosin staining. Nutritional status categorized using BMI chart. Data were analyzed using Chi-square test, Statistical Product, and Service Solutions version 20. RESULTS: From the total 157 stool examined in the laboratory, there were 60 (38.2%) children positively infected with various kinds of intestinal parasites. Mostly the infection is caused by Blastocystis hominis, which infects 44 children (69.4%). The other infection is caused by Giardia lamblia (15.3%), Trichuris trichiura (1.4%), and hookworm (1.4%), and mixed infection of B. hominis and Escherichia coli (4.2%) and B. hominis with G. lamblia (4.2%). From the total of infected children, 17 children (28.3%) have BMI below 5th percentile, and it was considered as malnourished. Moreover, 67 uninfected children have normal nutritional status. Statistically, there is an association between intestinal parasitic infection and nutritional status in school-aged children in South Jakarta (P < 0.05). CONCLUSION: The incidence of intestinal parasitic infection in school-aged children is 38.2%. Moreover, 28.3% of the infected children were malnourished and it is suggested that children with intestinal parasite infection have low nutritional status. © 2021 Ika Puspa Sari, Sacha Audindra, Aqila S. Zhafira, Arin A. Rahma, Cut V. Syarira, Sri Wahdini.	Malnourish; Parasitic Infection; Primary Schools; South Jakarta	Article; Blastocystis hominis; body mass; child; cross-sectional study; disease association; Escherichia coli; feces analysis; female; Giardia intestinalis; human; Indonesia; intestine parasite; major clinical study; male; malnutrition; mixed infection; nutritional status; obesity; parasitosis; prevalence; primary school; questionnaire; seasonal variation; Trichuris trichiura; underweight	Open Access Macedonian Journal of Medical Sciences	18579655		Article	Q3	288	15252	View
877	Negara J.D.K., Mudjianto S., Budikayanti A., Adhitya Nugraha P.P.	57221389254;57193794731;57194713932;57221981778;	The effect of gamma wave optimization and attention on hitting skills in softball	2021	International Journal of Human Movement and Sports Sciences	9	1		103	109		https://www.scopus.com/inward/record.uri?eid=2-s2.0-85100846277&doi=10.13189%2fsaj.2021.090114&partnerID=40&md5=572b9a6bf2d4f86222486dfb5b12188a	Department of Sport Education, Faculty of Sport Education and Health, Universitas Pendidikan Indonesia, Bandung, West Java, 40154, Indonesia; Department of Neurology, Faculty of Medicine, Universitas Indonesia, Jakarta, 10440, Indonesia	Negara, J.D.K., Department of Sport Education, Faculty of Sport Education and Health, Universitas Pendidikan Indonesia, Bandung, West Java, 40154, Indonesia; Mudjianto, S., Department of Sport Education, Faculty of Sport Education and Health, Universitas Pendidikan Indonesia, Bandung, West Java, 40154, Indonesia; Budikayanti, A., Department of Neurology, Faculty of Medicine, Universitas Indonesia, Jakarta, 10440, Indonesia; Adhitya Nugraha, P.P., Department of Sport Education, Faculty of Sport Education and Health, Universitas Pendidikan Indonesia, Bandung, West Java, 40154, Indonesia	Hitting the ball is a complicated ability in softball academicie, because in appreciation to prioritizing movement skills, cognitive appearances additionally need to be investigated, one of which is attention. Meanwhile, going to hit the ball requires excellent attention for an individual student. Exhibiting gamma waves further influence arrangements of hitting performance. The objectives of this study were first, to determine the negative functional correlation between gamma brain waves and hitting skills, then second to know the positive functional correlation between attention and hitting skills and third to determine the effect of attention on increasing hitting skills. The method used in this research is an experimental method with a one-group pretest-posttest design research design. The sampling technique in this study was using a saturated sampling technique. This investigation amounted to 20 subjects, in the calculation of the Pearson product-moment correlation test using SPSS v.23. The first results collected were p-value 0.026 with an r square value of 0.25, so there is a significant negative functional correlation between gamma brain waves and hitting skills in softball learning of 25%. The second issue obtained p-value 0.017 with an r square value of 0.28, so there is a significant positive functional correlation between attention and hitting skills in softball learning by 28%. Furthermore, thirdly, the results obtained p-value 0.0001 between pre-test and post-test, with a significant increase in skills of 70.17%, so there is a significant influence between attention and hitting skills. © 2021 by authors, all rights reserved.	Attention; Gamma Brain Waves; Hitting Skills; Softball Games		Horizon Research Publishing	23814381		Article	Q4	132	25155	View
890	Elliyanti A., Rustam R., Tofrizal T., Yenita Y., Susanto Y.D.B.	57217097313;57210705603;57219663511;57221789235;57197866044;	Evaluating the natrium iodide symporter expressions in thyroid tumors	2021	Open Access Macedonian Journal of Medical Sciences	9	B		18	23		https://www.scopus.com/inward/record.uri?eid=2-s2.0-85100161267&doi=10.3889%2foamjms.2021.5534&partnerID=40&md5=f5dd69104ea66dab03a6a98ac2928162	Department of Medical Physics, Faculty of Medicine, Universitas Andalas, Padang, Indonesia; Division of Nuclear Medicine, Department of Radiology, Dr. M.Djamil Hospital, Padang, Indonesia; Department of Surgery, Faculty of Medicine, Universitas Andalas, Padang, Indonesia; Department of Pathology Anatomy, Faculty of Medicine, Universitas Andalas, Padang, Indonesia; Department of Pathology Anatomy, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia	Elliyanti, A., Department of Medical Physics, Faculty of Medicine, Universitas Andalas, Padang, Indonesia, Division of Nuclear Medicine, Department of Radiology, Dr. M.Djamil Hospital, Padang, Indonesia; Rustam, R., Department of Surgery, Faculty of Medicine, Universitas Andalas, Padang, Indonesia; Tofrizal, T., Department of Pathology Anatomy, Faculty of Medicine, Universitas Andalas, Padang, Indonesia; Yenita, Y., Department of Pathology Anatomy, Faculty of Medicine, Universitas Andalas, Padang, Indonesia; Susanto, Y.D.B., Department of Pathology Anatomy, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia	BACKGROUND: Decreased Natrium iodide symporter (NIS) expression levels or diminished NIS targeting thyroid cancer cells’ plasma membrane leads to radioiodine-refractory disease. AIM: The aim of this study was to analyze the NIS expression in thyroid tumors. MATERIALS AND METHODS: The samples were thyroid tissues of patients who underwent surgery for a thyroid tumor. The tissues were processed for NIS protein expressions by immunohistochemistry (IHC) and Western blot (WB). Graves’ disease samples were used as positive controls. The samples were incubated without the primary antibody, and they were used as negative controls for IHC examination. Na+/K+ ATPase was a plasma membrane protein marker in the WB procedure. RESULTS: Twenty-nine samples were assessed for NIS protein. All of them showed the expression in the cytoplasm with intensity 1+ to 3+ with Allred score 3-8. Fourteen out of 29 cases (48.2%) showed NIS cytoplasm staining intensity ≥2+ consist of 10 papillary thyroid cancer (PTC), three follicular thyroid cancer, and one adenoma. Membrane staining was found in 2 samples of PTC (6.9%). Six samples (adenoma 1 sample, PTC 5 samples) showed NIS expression at membrane very weak (1+); they were considered as negative. NIS protein has several bands of ~ 80 kDa, ~ 62 kDa, and ~ 49 kDa. CONCLUSION: NIS expression in thyroid cancer mostly expresses in the cytoplasm instead of the membrane. NIS will play a functional role in the membrane to bring iodine across the membrane against the concentration. It can be the main reason for the lack of response of radioiodine in some differentiated thyroid cancers. © 2021 Aisyah Elliyanti, Rony Rustam, Tofrizal Tofrizal, Yenita Yenita, Susanto YDB.	Follicular thyroid cancer; Immunohistochemistry; Membrane staining; Papillary thyroid cancer; Western blot		Open Access Macedonian Journal of Medical Sciences	18579655		Article	Q3	288	15252	View
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165	Vandenplas Y., Hegar B., Munasir Z., Astawan M., Juffrie M., Bardosono S., Sekartini R., Basrowi R.W., Wasito E.	57223670656;6506273944;7801694370;55622754000;6603321832;21933841000;57224503576;57024210400;6506940239;	The role of soy plant-based formula supplemented with dietary fiber to support children's growth and development: An expert opinion	2021	Nutrition	90		111278			1	https://www.scopus.com/inward/record.uri?eid=2-s2.0-85106303526&doi=10.1016%2fj.nut.2021.111278&partnerID=40&md5=6f39985da49e44dfd1fa5832b4927b0a	KidZ Health Castle, UZ Brussel, Vrije Universiteit Brussel, Belgium; Department of Pediatric, Faculty of Medicine, Universitas Indonesia, Cipto Mangunkusumo General HospitalJakarta, Indonesia; Department of Food Science and Technology, IPB University, Bogor, Indonesia; Department of Child Health, Faculty of Medicine, Universitas Gajah MadaYogyakarta, Indonesia; Department of Nutrition, Faculty of Medicine, Universitas Indonesia, Cipto Mangunkusumo General HospitalJakarta, Indonesia; Danone Specialized Nutrition IndonesiaJakarta, Indonesia	Vandenplas, Y., KidZ Health Castle, UZ Brussel, Vrije Universiteit Brussel, Belgium; Hegar, B., Department of Pediatric, Faculty of Medicine, Universitas Indonesia, Cipto Mangunkusumo General HospitalJakarta, Indonesia; Munasir, Z., Department of Pediatric, Faculty of Medicine, Universitas Indonesia, Cipto Mangunkusumo General HospitalJakarta, Indonesia; Astawan, M., Department of Food Science and Technology, IPB University, Bogor, Indonesia; Juffrie, M., Department of Child Health, Faculty of Medicine, Universitas Gajah MadaYogyakarta, Indonesia; Bardosono, S., Department of Nutrition, Faculty of Medicine, Universitas Indonesia, Cipto Mangunkusumo General HospitalJakarta, Indonesia; Sekartini, R., Department of Pediatric, Faculty of Medicine, Universitas Indonesia, Cipto Mangunkusumo General HospitalJakarta, Indonesia; Basrowi, R.W., Danone Specialized Nutrition IndonesiaJakarta, Indonesia; Wasito, E., Danone Specialized Nutrition IndonesiaJakarta, Indonesia	Objectives: Soy-based formula has evolved in usage and processing technology since its introduction in 1909, and has been used as substitute formula for infants or children with cow milk allergy since 1929. At present, personal opinions, religious background, availability, palatability, and cost are part of the reasons soy-based formula is chosen. Technology in processing soy-based formula has evolved from using soy flour to soy protein isolate, which provides advantages. However, concerns remain regarding the impact of its use on the growth and development of children. Methods: An expert meeting, attended by 12 experts, was initiated in Jakarta, Indonesia, to obtain an evidence-based consensus on the role of soy protein isolate formula, as well as its nutritional value to support growth and development. Results: Ensuring that plant-based formula (i.e., soy protein isolate formula) is fortified with key nutrients, such as calcium, iron, and dietary fiber is important. Conclusions: Consensus was achieved, concluding that soy protein isolate formula is safe, affordable, and an alternative option for cow's milk–based formula for term infants. © 2021 The Authors	Child growth and development; Expert opinion; Soy-based infant formula	calcium; iron; soybean protein; artificial milk; child growth; developmental stage; diet supplementation; dietary fiber; human; nutritional value; patient safety; priority journal; Review; soybean; soybean meal; animal; artificial milk; bovine; child; dietary fiber; expert witness; female; infant; milk allergy; Animals; Cattle; Child; Dietary Fiber; Expert Testimony; Female; Humans; Infant; Infant Formula; Milk Hypersensitivity; Soybean Proteins	Elsevier Inc.	08999007	34004412	Review	Q2	1002	4372	View
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374	Prasasty V.D., Hutagalung R.A., Gunadi R., Sofia D.Y., Rosmalena R., Yazid F., Sinaga E.	56019989700;57196436040;57223239895;57223238377;56891769500;57207890516;6503946360;	Prediction of human-Streptococcus pneumoniae protein-protein interactions using logistic regression	2021	Computational Biology and Chemistry	92		107492				https://www.scopus.com/inward/record.uri?eid=2-s2.0-85105320211&doi=10.1016%2fj.compbiolchem.2021.107492&partnerID=40&md5=5e13061470115aaa99774510455cd385	Faculty of Biotechnology, Atma Jaya Catholic University of Indonesia, Jakarta, 12930, Indonesia; Department of Biology, Faculty of Life Sciences, Universitas Surya, Tangerang, Banten 15143, Indonesia; Department of Medical Chemistry, Faculty of Medicine, Universitas Indonesia, Jakarta, 10430, Indonesia; Faculty of Biology, Universitas Nasional, Jakarta, 12520, Indonesia	Prasasty, V.D., Faculty of Biotechnology, Atma Jaya Catholic University of Indonesia, Jakarta, 12930, Indonesia; Hutagalung, R.A., Faculty of Biotechnology, Atma Jaya Catholic University of Indonesia, Jakarta, 12930, Indonesia; Gunadi, R., Department of Biology, Faculty of Life Sciences, Universitas Surya, Tangerang, Banten 15143, Indonesia; Sofia, D.Y., Department of Biology, Faculty of Life Sciences, Universitas Surya, Tangerang, Banten 15143, Indonesia; Rosmalena, R., Department of Medical Chemistry, Faculty of Medicine, Universitas Indonesia, Jakarta, 10430, Indonesia; Yazid, F., Department of Medical Chemistry, Faculty of Medicine, Universitas Indonesia, Jakarta, 10430, Indonesia; Sinaga, E., Faculty of Biology, Universitas Nasional, Jakarta, 12520, Indonesia	Streptococcus pneumoniae is a major cause of mortality in children under five years old. In recent years, the emergence of antibiotic-resistant strains of S. pneumoniae increases the threat level of this pathogen. For that reason, the exploration of S. pneumoniae protein virulence factors should be considered in developing new drugs or vaccines, for instance by the analysis of host-pathogen protein-protein interactions (HP-PPIs). In this research, prediction of protein-protein interactions was performed with a logistic regression model with the number of protein domain occurrences as features. By utilizing HP-PPIs of three different pathogens as training data, the model achieved 57–77 % precision, 64–75 % recall, and 96–98 % specificity. Prediction of human-S. pneumoniae protein-protein interactions using the model yielded 5823 interactions involving thirty S. pneumoniae proteins and 324 human proteins. Pathway enrichment analysis showed that most of the pathways involved in the predicted interactions are immune system pathways. Network topology analysis revealed β-galactosidase (BgaA) as the most central among the S. pneumoniae proteins in the predicted HP-PPI networks, with a degree centrality of 1.0 and a betweenness centrality of 0.451853. Further experimental studies are required to validate the predicted interactions and examine their roles in S. pneumoniae infection. © 2021 Elsevier Ltd	Host-pathogen protein-protein interactions; Logistic regression; Network centrality; Pathway enrichment; Streptococcus pneumoniae	Forecasting; Logistic regression; Betweenness centrality; Degree centrality; Logistic Regression modeling; Network topology analysis; Protein-protein interactions; Resistant strains; Streptococcus pneumoniae; Virulence factors; Proteins; protein; protein binding; chemistry; host pathogen interaction; human; statistical model; Streptococcus pneumoniae; Host-Pathogen Interactions; Humans; Logistic Models; Protein Binding; Proteins; Streptococcus pneumoniae	Elsevier Ltd	14769271	33964803	Article	Q3	416	11737	View
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548	Pranata R., Henrina J., Lim M.A., Lawrensia S., Yonas E., Vania R., Huang I., Lukito A.A., Suastika K., Kuswardhani R.A.T., Setiati S.	57201973901;57218482646;57216039756;57219781613;57201987097;57208328436;57208576645;57213835420;8736266500;36863900500;14325991900;	Clinical frailty scale and mortality in COVID-19: A systematic review and dose-response meta-analysis: Clinical Frailty Scale in COVID-19	2021	Archives of Gerontology and Geriatrics	93		104324			53	https://www.scopus.com/inward/record.uri?eid=2-s2.0-85098467342&doi=10.1016%2fj.archger.2020.104324&partnerID=40&md5=f9eef93f03ae5cb88ddf255820cbd190	Faculty of Medicine, Universitas Pelita Harapan, Tangerang, Indonesia; Siloam Heart Institute, Jakarta, Indonesia; Ken Saras General Hospital, Semarang, Indonesia; Faculty of Medicine, Universitas YARSI, Jakarta, Indonesia; Division of Plastic, Reconstructive and Aesthetic, Department of Surgery, Faculty of Medicine, Udayana University, Sanglah General Hospital, Bali, Indonesia; Department of Internal Medicine, Faculty of Medicine, Universitas Padjadjaran, Hasan Sadikin General Hospital, Bandung, Indonesia; Department of Cardiology and Vascular Medicine, Siloam Hospitals Lippo Village, Tangerang, Indonesia; Division of Endocrinology and Metabolism, Department of Internal Medicine, Faculty of Medicine, Udayana University Denpasar, Bali, Indonesia; Division of Geriatrics, Department of Internal Medicine, Faculty of Medicine, Udayana University, Sanglah Teaching Hospital, Denpasar - Bali, Indonesia; Division of Geriatrics, Department of Internal Medicine, Faculty of Medicine, Universitas Indonesia-Cipto Mangunkusumo General Hospital, Jakarta, Indonesia	Pranata, R., Faculty of Medicine, Universitas Pelita Harapan, Tangerang, Indonesia; Henrina, J., Siloam Heart Institute, Jakarta, Indonesia; Lim, M.A., Faculty of Medicine, Universitas Pelita Harapan, Tangerang, Indonesia; Lawrensia, S., Ken Saras General Hospital, Semarang, Indonesia; Yonas, E., Faculty of Medicine, Universitas YARSI, Jakarta, Indonesia; Vania, R., Faculty of Medicine, Universitas Pelita Harapan, Tangerang, Indonesia, Division of Plastic, Reconstructive and Aesthetic, Department of Surgery, Faculty of Medicine, Udayana University, Sanglah General Hospital, Bali, Indonesia; Huang, I., Faculty of Medicine, Universitas Pelita Harapan, Tangerang, Indonesia, Department of Internal Medicine, Faculty of Medicine, Universitas Padjadjaran, Hasan Sadikin General Hospital, Bandung, Indonesia; Lukito, A.A., Department of Cardiology and Vascular Medicine, Siloam Hospitals Lippo Village, Tangerang, Indonesia; Suastika, K., Division of Endocrinology and Metabolism, Department of Internal Medicine, Faculty of Medicine, Udayana University Denpasar, Bali, Indonesia; Kuswardhani, R.A.T., Division of Geriatrics, Department of Internal Medicine, Faculty of Medicine, Udayana University, Sanglah Teaching Hospital, Denpasar - Bali, Indonesia; Setiati, S., Division of Geriatrics, Department of Internal Medicine, Faculty of Medicine, Universitas Indonesia-Cipto Mangunkusumo General Hospital, Jakarta, Indonesia	Introduction: National Institute for Health and Care Excellence (NICE) endorsed clinical frailty scale (CFS) to help with decision-making. However, this recommendation lacks an evidence basis and is controversial. This meta-analysis aims to quantify the dose-response relationship between CFS and mortality in COVID-19 patients, with a goal of supplementing the evidence of its use. Methods: We performed a systematic literature search from several electronic databases up until 8 September 2020. We searched for studies investigating COVID-19 patients and reported both (1) CFS and its distribution (2) CFS and its association with mortality. The outcome of interest was mortality, defined as clinically validated death or non-survivor. The odds ratio (ORs) will be reported per 1% increase in CFS. The potential for a non-linear relationship based on ORs of each quantitative CFS was examined using restricted cubic splines with a three-knots model. Results: There were a total of 3817 patients from seven studies. Mean age was 80.3 (SD 8.2), and 53% (48–58%) were males. The pooled prevalence for CFS 1–3 was 34% (32–36%), CFS 4–6 was 42% (40–45%), and CFS 7–9 was 23% (21–25%). Each 1-point increase in CFS was associated with 12% increase in mortality (OR 1.12 (1.04, 1.20), p = 0.003; I2: 77.3%). The dose-response relationship was linear (Pnon-linearity=0.116). The funnel-plot analysis was asymmetrical; Trim-and-fill analysis by the imputation of two studies on the left side resulted in OR of 1.10 [1.03, 1.19]. Conclusion: This meta-analysis showed that increase in CFS was associated with increase in mortality in a linear fashion. © 2020 Elsevier B.V.	Age; Coronavirus; COVID-19; Frailty; Prognosis; Risk stratification	Article; Clinical Frailty Scale; coronavirus disease 2019; data analysis; functional status assessment; human; medical research; mortality; odds ratio; outcome assessment; prevalence; priority journal; quantitative analysis; systematic error; systematic review; frailty; male; meta analysis; very elderly; Aged, 80 and over; COVID-19; Frailty; Humans; Male; Prevalence; SARS-CoV-2	Elsevier Ireland Ltd	01674943	33352430	Article	Q1	985	4466	View
716	Dewi S., Sadikin M., Mulyawan W.	57192904541;36981411100;57192910410;	Oxidative stress in the heart of rats exposed to acute intermittent hypobaric hypoxia	2021	Ukrainian Biochemical Journal	93	3		68	74		https://www.scopus.com/inward/record.uri?eid=2-s2.0-85114748388&doi=10.15407%2fubj93.03.068&partnerID=40&md5=a11d4d4d31ac5bf34a38f63a8507d433	Department of Biochemistry and Molecular Biology, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Department of Aerophysiology, Air Force Indonesian National Army, Lakespra Saryanto, Jakarta, Indonesia	Dewi, S., Department of Biochemistry and Molecular Biology, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Sadikin, M., Department of Biochemistry and Molecular Biology, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Mulyawan, W., Department of Aerophysiology, Air Force Indonesian National Army, Lakespra Saryanto, Jakarta, Indonesia	It is known that the altitude area causes hypoxic conditions due to the low oxygen partial pressure. This study was conducted to estimate oxidative stress indices in the heart tissue after Wister rats exposure to the acute intermittent hypobaric hypoxia. Hypobaric hypoxia exposure was simulated by keeping the rats in a hypobaric chamber for 1 min at 35,000 feet altitude. After that the altitude was gradually reduced to 30,000 and 25,000 feet and maitained for 5 min. 25 male Wistar rats were divided into control group and four treatment groups (I-IV), consisting of rats exposed 1, 2, 3 and 4 times to hypobaric hypoxia with a frequency once a week. The animals were removed from the experiment at the height of 18,000 feet and the heart tissue was obtained. The carbonyl groups and MDA levels and superoxide dismutase and catalase activity were exami-ned in the supernatant of the heart tissue homogenate. In the samples of group I, the decrease in catalase activity with a simultaneous notable increase in carbonyl groups level was observed compared to control. In the samples of groups III and IV, the carbonyl level normalized and the activity of both antioxidant enzymes increased significantly. It was concluded that the increase of antioxidant enzymes activity can contribute to cardiac tissue adaptive response to acute hypobaric hypoxia exposure. © 2021 Dewi S. et al.	Acute intermittent hypobaric hypoxia; Antioxidant enzymes; Heart; Oxidative stress		Palladin Institute of Biochemistry of the NASU	24094943		Article	Q4	173	21241	View

Publikasi Scopus 926 artikel (Per 14 Maret 2022)