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Id	Authors	Author S Id	Title	Year	Source Title	Volume	Issue	Art No	Page Start	Page End	Cited By	Link	Affiliations	Authors With Affiliations	Abstract	Author Keywords	Index Keywords	Publisher	Issn	Pubmed Id	Document Type	Sjr Best Quartile	Sjr	Sjr Rank
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93(1)
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854	Kirana A.N., Prafiantini E., Hardiany N.S.	57222361321;57193088368;57192910605;	Protein intake and loss of proteostasis in the eldery	2021	Ukrainian Biochemical Journal	93	1		30	39		https://www.scopus.com/inward/record.uri?eid=2-s2.0-85102434761&doi=10.15407%2fubj93.01.030&partnerID=40&md5=e09be01091937944ac8ad3197ad54b2c	Department of Nutrition, Faculty of Medicine, Universitas Indonesia - Dr. Cipto Mangunkusumo General Hospital, Jakarta, Indonesia; Department of Biochemistry and Molecular Biology, Faculty of Medicine, Universitas Indonesia, Indonesia; Center of Hypoxia and Oxidative Stress Studies, Faculty of Medicine, Universitas Indonesia, Indonesia	Kirana, A.N., Department of Nutrition, Faculty of Medicine, Universitas Indonesia - Dr. Cipto Mangunkusumo General Hospital, Jakarta, Indonesia; Prafiantini, E., Department of Nutrition, Faculty of Medicine, Universitas Indonesia - Dr. Cipto Mangunkusumo General Hospital, Jakarta, Indonesia; Hardiany, N.S., Department of Biochemistry and Molecular Biology, Faculty of Medicine, Universitas Indonesia, Indonesia, Center of Hypoxia and Oxidative Stress Studies, Faculty of Medicine, Universitas Indonesia, Indonesia	Ageing is a process of declining bodily function and a major risk factor of chronic diseases. The declining bodily function in ageing can cause loss of proteostasis (protein homeostasis), which is a balance between protein synthesis, folding, modification and degradation. For the elderly, adequate protein intake is necessary to prevent sarcopenia, frailty, fracture and osteoporosis as well as reduced resistance to infection. However, increasing the protein intake can enhance the risk of oxidized protein formation, loss of proteostasis and degenerative disorder occurrence. On the other hand, several studies show that protein restriction would increase longevity. The aim of this review was to explain the importance of determining the right amount and composition of protein intake for the elderly. Oxidative stress and molecular mechanism of proteostasis loss in ageing cells as well as its suppression pathway by protein restriction are discussed in this review. © 2021 Kirana A. N. et al.	Ageing; Dietary proteins; MTOR; Oxidative stress; Proteostasis loss		Palladin Institute of Biochemistry of the NASU	24094943		Article	Q4	173	21241	View
95(1)
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105	Akmal M.M., Pabittei D.R., Prapassaro T., Suhartono R., Moll F.L., van Herwaarden J.A.	57212520722;36722034600;57205214358;57218884615;7103009095;6602663510;	A systematic review of the current status of interventions for type II endoleak after EVAR for abdominal aortic aneurysms	2021	International Journal of Surgery	95		106138				https://www.scopus.com/inward/record.uri?eid=2-s2.0-85117194344&doi=10.1016%2fj.ijsu.2021.106138&partnerID=40&md5=04d622b377ba196029ff5e68c6be3e4c	Departement of vascular surgery, University Medical Center Utrecht, Utrecht, Netherlands; Vascular surgery Division, Departement of Surgery, Faculty of Medicine, Cipto Mangunkusumo Hospital, University of Indonesia, Indonesia; Departement of Physiology, Hasanudin University, Indonesia; Departement of vascular surgery, Siriraj Hospital, Mahidol UniversityBangkok, Thailand	Akmal, M.M., Departement of vascular surgery, University Medical Center Utrecht, Utrecht, Netherlands, Vascular surgery Division, Departement of Surgery, Faculty of Medicine, Cipto Mangunkusumo Hospital, University of Indonesia, Indonesia; Pabittei, D.R., Departement of Physiology, Hasanudin University, Indonesia; Prapassaro, T., Departement of vascular surgery, University Medical Center Utrecht, Utrecht, Netherlands, Departement of vascular surgery, Siriraj Hospital, Mahidol UniversityBangkok, Thailand; Suhartono, R., Vascular surgery Division, Departement of Surgery, Faculty of Medicine, Cipto Mangunkusumo Hospital, University of Indonesia, Indonesia; Moll, F.L., Departement of vascular surgery, University Medical Center Utrecht, Utrecht, Netherlands; van Herwaarden, J.A., Departement of vascular surgery, University Medical Center Utrecht, Utrecht, Netherlands	Objective: To study the mid- and long-term outcomes of type II endoleak treatment after EVAR and the technical aspects of different techniques to exclude endoleaks which different embolic agents. Methods: A systematic review was performed using the approach recommended by the PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-Analyses) guidelines for meta-analyses of interventional studies. The comprehensive search was conducted using the following database: MEDLINE, EMBASE, and the Cochrane Library. Patient characteristic, intervention approaches, embolic agents, and results at mid and long term follow up were studied. Results: A total of 6 studies corresponding to a total of 141 patients fulfilled the inclusion criteria with a mean age of 73–78.6 years and a mean duration of follow up varying from 25 to 42 months. There were different techniques for embolization used (translumbar, transarterial, and transcaval approach) with various types of embolic agents. In all studies, the indication for embolization of the type II endoleaks was sac enlargement of more than 5 mm. A wide range of technical success rate was reported regardless of the intervention strategy being used (17,6%–100%). The overall technical success rate of all studies was 62%. Conclusion: This systematic review shows that there is a wide variety of techniques to exclude a persistent type II endoleak. Different kinds of embolic agents have be used. Due to a lack of peer reviewed data on longterm follow-up, it was not possible to come to recommendations what treatment would be the best for a durable exclusion of a persistent type II endoleak after an initially successful EVAR. There remains an urgent need for proper executed studies, either randomized or with close observation in relation to longer follow-up. © 2021 The Authors	Abdominal aorta aneurysm; Aneurysm repair; Endoleaks; Endovascular aneurysm repair; Type	ethylene vinyl alcohol copolymer; glue; iodinated poppyseed oil; onyx copolymer; thrombin; abdominal aortic aneurysm; aged; artificial embolization; clinical outcome; cohort analysis; conservative treatment; data extraction; endoleak; endovascular aneurysm repair; follow up; human; laparoscopic surgery; major clinical study; meta analysis; outcome assessment; postoperative infection; practice guideline; Preferred Reporting Items for Systematic Reviews and Meta-Analyses; quality control; Review; selective transcaval embolization; surgical approach; systematic review; transarterial embolization; translumbar embolization; treatment duration; treatment indication; type ii endoleak; very elderly; adverse event; artificial embolization; endoleak; endovascular surgery; Aged; Aortic Aneurysm, Abdo	Elsevier Ltd	17439191	34637951	Review	Q1	1315	2831	View
96(1)
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323	Rizka A., Setiati S., Sadikin M., Mansur I.G.	57203243658;14325991900;57205093115;6603222374;	Immunomodulatory effect of in vitro calcitriol in fit and frail elderly	2021	International Immunopharmacology	96		107737			1	https://www.scopus.com/inward/record.uri?eid=2-s2.0-85105325886&doi=10.1016%2fj.intimp.2021.107737&partnerID=40&md5=bd310cacaf61c4b89ad48ac61ee52389	Division of Geriatric Medicine, Department of Internal Medicine Faculty of Medicine Universitas Indonesia, Cipto Mangunkusumo National Hospital, Jakarta 10430, Indonesia; Metabolic Vascular and Aging Cluster, Indonesian Medical Education and Research Institute Faculty of Medicine Universitas Indonesia, Jakarta 10430, Indonesia; Department of Biochemistry Faculty of Medicine Universitas Indonesia, Jakarta 10430, Indonesia; Department of Biology Faculty of Medicine Universitas Indonesia, Jakarta 10430, Indonesia	Rizka, A., Division of Geriatric Medicine, Department of Internal Medicine Faculty of Medicine Universitas Indonesia, Cipto Mangunkusumo National Hospital, Jakarta 10430, Indonesia, Metabolic Vascular and Aging Cluster, Indonesian Medical Education and Research Institute Faculty of Medicine Universitas Indonesia, Jakarta 10430, Indonesia; Setiati, S., Division of Geriatric Medicine, Department of Internal Medicine Faculty of Medicine Universitas Indonesia, Cipto Mangunkusumo National Hospital, Jakarta 10430, Indonesia; Sadikin, M., Department of Biochemistry Faculty of Medicine Universitas Indonesia, Jakarta 10430, Indonesia; Mansur, I.G., Department of Biology Faculty of Medicine Universitas Indonesia, Jakarta 10430, Indonesia	Introduction: Effect of calcitriol on PBMCs of healthy adults have been well studied but not much is known about its effect on the PBMCs of elderly patients with various degree of frailty syndrome and immune senescence. This study was aimed to assess the effect of in vitro calcitriol immunomodulatory effect on IL-6, IL-10 and IFN-γ in elderly patients who were fit, pre-frail and frail to see which group of patients might get the most benefit of calcitriol. Methods: This study was an experimental study on the PBMCs of 24 elderly people, of which 8 subjects each were in fit, pre-frail and frail categories based on the Cardiovascular Health Study criteria. IL-6, IL-10, and IFN-γ were examined by ELISA, before and after administration of lipopolysaccharide and 100 pg/mL calcitriol into PBMC cultures in vitro. Result: The mean serum vitamin D level was 26.2 (2.4) ng/ml. Vitamin D level is decreasing along with worsening of frailty status. After LPS induction, calcitriol did not reduce IL-6 and IFN-γ in all the groups. Calcitriol increased IL-10 in all groups, with the most observed change in the pre-frail group. Conclusion: In vitro administration of calcitriol showed anti-inflammatory potential by increasing IL-10 mainly in pre-frail subjects. © 2021 Elsevier B.V.	Calcitriol; Elderly; Frail; In vitro	calcitriol; gamma interferon; interleukin 10; interleukin 6; lipopolysaccharide; vitamin D; calcitriol; gamma interferon; IFNG protein, human; IL10 protein, human; IL6 protein, human; interleukin 10; interleukin 6; vitamin D; aged; Article; cell culture; clinical article; controlled study; enzyme linked immunosorbent assay; experimental study; female; frail elderly; frailty; human; human cell; immunomodulation; in vitro study; male; peripheral blood mononuclear cell; priority journal; protein blood level; vitamin blood level; age; blood; drug effect; frail elderly; immunology; immunomodulation; metabolism; mononuclear cell; pharmacology; physiology; Age Factors; Aged; Calcitriol; Calcium-Regulating Hormones and Agents; Female; Frail Elderly; Humans; Immunomodulation; In Vitro Techniques; I	Elsevier B.V.	15675769	33965881	Article	Q1	1152	3523	View
97(2)
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168	Andriyati R., Firman D., Kurniawati Y., Alkatiri A.A., Pranata R., Muliawan H.S., Rossimarina V., Soerianata S.	57219712507;54898724100;57199153189;57210302708;57201973901;57203644653;57219708502;6504387197;	Improved clinical outcome with biodegradable polymer drug-eluting stents compared to durable polymer drug-eluting stents for primary percutaneous coronary intervention	2021	Postgraduate Medical Journal	97	1152		638	643		https://www.scopus.com/inward/record.uri?eid=2-s2.0-85094912557&doi=10.1136%2fpostgradmedj-2020-138243&partnerID=40&md5=10b39bd26552fd6e6283165f7c0afe78	Department of Cardiology and Vascular Medicine, Faculty of Medicine, Universitas Indonesia, National Cardiovascular Center Harapan Kita, Jakarta, Indonesia; Faculty of Medicine, Universitas Pelita Harapan, Tangerang, Indonesia	Andriyati, R., Department of Cardiology and Vascular Medicine, Faculty of Medicine, Universitas Indonesia, National Cardiovascular Center Harapan Kita, Jakarta, Indonesia; Firman, D., Department of Cardiology and Vascular Medicine, Faculty of Medicine, Universitas Indonesia, National Cardiovascular Center Harapan Kita, Jakarta, Indonesia; Kurniawati, Y., Department of Cardiology and Vascular Medicine, Faculty of Medicine, Universitas Indonesia, National Cardiovascular Center Harapan Kita, Jakarta, Indonesia; Alkatiri, A.A., Department of Cardiology and Vascular Medicine, Faculty of Medicine, Universitas Indonesia, National Cardiovascular Center Harapan Kita, Jakarta, Indonesia; Pranata, R., Faculty of Medicine, Universitas Pelita Harapan, Tangerang, Indonesia; Muliawan, H.S., Department of Cardiology and Vascular Medicine, Faculty of Medicine, Universitas Indonesia, National Cardiovascular Center Harapan Kita, Jakarta, Indonesia; Rossimarina, V., Department of Cardiology and Vascular Medicine, Faculty of Medicine, Universitas Indonesia, National Cardiovascular Center Harapan Kita, Jakarta, Indonesia; Soerianata, S., Department of Cardiology and Vascular Medicine, Faculty of Medicine, Universitas Indonesia, National Cardiovascular Center Harapan Kita, Jakarta, Indonesia	Background Studies comparing the clinical outcomes of second-generation biodegradable polymer drug-eluting stents (BP-DES) and second-generation durable polymer drug-eluting stents (DP-DES) in patients with ST-segment elevation myocardial infarction (STEMI) with follow-up duration of more than 1 year are still limited. Objective This study aimed to compare the 2-year clinical outcome of BP-DES with second-generation DP-DES in patients undergoing primary percutaneous coronary intervention (PPCI). Methods This is a retrospective cohort study in patients with STEMI, the primary endpoint was major adverse cardiac events (MACE) defined as recurrent myocardial infarction, total repeat revascularisation and cardiac death. The secondary endpoint was stent thrombosis (ST) defined as definite, probable or possible. Results A total of 400 patients were analysed (197 BP-DES groups and 203 DP-DES groups). BP-DES were independently associated with lower incidence of MACE (adjusted HR 0.67, 95% CI 0.21 to 0.91, p=0.005) and ST (adjusted HR 0.62, 95% CI 0.19 to 0.73, p<0.016) within 2 years of follow-up. Subgroup analysis of MACE individual components showed that BP-DES were associated with lower cardiac deaths (HR 0.35; 95% CI 0.18 to 0.94; p<0.001) compared to DP-DES, but not recurrent myocardial infarction and total repeat revascularisation. Conclusions BP-DES were associated with better clinical outcomes compared to second-generation DP-DES in patients with STEMI undergoing PPCI. ©	adult cardiology; Cardiology; coronary heart disease; coronary intervention; ischaemic heart disease; myocardial infarction	acetylsalicylic acid; beta adrenergic receptor blocking agent; clopidogrel; creatinine; glucose; hydroxymethylglutaryl coenzyme A reductase inhibitor; ticagrelor; troponin I; troponin T; polymer; acute heart infarction; adult; Article; chronic kidney failure; clinical outcome; cohort analysis; controlled clinical trial; controlled study; coronary angiography; diabetes mellitus; diastolic blood pressure; dual antiplatelet therapy; dyslipidemia; female; fibrinolytic therapy; heart death; heart infarction; heart left ventricle ejection fraction; heart rate; human; hypertension; incidence; major adverse cardiac event; major clinical study; male; middle aged; mortality; non ST segment elevation myocardial infarction; observational study; percutaneous coronary intervention; retrospective study;	BMJ Publishing Group	00325473	32796116	Article	Q2	568	8912	View
559	Kesuma Y., Sekartini R., Timan I.S., Kurniawan A., Bardosono S., Firmansyah A., Vandenplas Y.	57209278648;57224503576;6602793366;6506883360;21933841000;6602915502;57223670656;	Irritable bowel syndrome in Indonesian adolescents	2021	Jornal de Pediatria	97	2		197	203		https://www.scopus.com/inward/record.uri?eid=2-s2.0-85081734309&doi=10.1016%2fj.jped.2020.02.001&partnerID=40&md5=b8d2dcd5c96832dce29f4c05c71dd219	Sriwijaya University and Moh Hoesin Hospital, Faculty of Medicine, Department of Pediatrics, Palembang, Indonesia; University of Indonesia and Cipto Mangunkusumo Hospital, Faculty of Medicine, Department of Pediatrics, Jakarta, Indonesia; University of Indonesia Cipto Mangunkusumo Hospital, Faculty of Medicine, Department of Clinical Pathology, Jakarta, Indonesia; University of Indonesia, Faculty of Medicine, Department of Parasitology, Jakarta, Indonesia; University of Indonesia, Faculty of Medicine, Department of Nutrition, Jakarta, Indonesia; Free University of Brussels, UZ Brussel Hospital, KidZ Health Castle, Brussels, Belgium	Kesuma, Y., Sriwijaya University and Moh Hoesin Hospital, Faculty of Medicine, Department of Pediatrics, Palembang, Indonesia; Sekartini, R., University of Indonesia and Cipto Mangunkusumo Hospital, Faculty of Medicine, Department of Pediatrics, Jakarta, Indonesia; Timan, I.S., University of Indonesia Cipto Mangunkusumo Hospital, Faculty of Medicine, Department of Clinical Pathology, Jakarta, Indonesia; Kurniawan, A., University of Indonesia, Faculty of Medicine, Department of Parasitology, Jakarta, Indonesia, University of Indonesia, Faculty of Medicine, Department of Nutrition, Jakarta, Indonesia; Bardosono, S., University of Indonesia, Faculty of Medicine, Department of Nutrition, Jakarta, Indonesia; Firmansyah, A., University of Indonesia and Cipto Mangunkusumo Hospital, Faculty of Medicine, Department of Pediatrics, Jakarta, Indonesia; Vandenplas, Y., Free University of Brussels, UZ Brussel Hospital, KidZ Health Castle, Brussels, Belgium	Objective: Irritable bowel syndrome is a frequent functional gastrointestinal disorder. The aims of this study were to investigate its epidemiology, focusing on the role of intestinal mucosal integrity and to evaluate the impact on the quality of life. Methods: A community-based survey applying a comparative cross sectional approach was conducted in six high schools in Palembang. Subjects were recruited using multistage random sampling divided in two groups. Rome III criteria were used to establish a diagnosis of IBS in combination with a questionnaire to determine risk factors. Determination of fecal alpha-1-antitrypsin and calprotectin levels was performed to determine impaired intestinal mucosal integrity. A questionnaire was used to evaluate how quality of life was affected by irritable bowel syndrome. Results: The survey was performed in 454 14−18 years old adolescents, of whom 30.2% fulfilled the Rome III criteria for IBS, with the following subtypes: 36.5% diarrhea, 18.9% constipation, 21.9% mixed, and 22.6% unclassified. Major risk factors were female gender, bullying, age 14–16 years, history of constipation and diarrhea, eating nuts, and drinking coffee, tea, and soft drinks. There was a significant association with intestinal inflammation (p = 0.013). A significantly impaired quality of life was found (p = 0.001). Conclusions: The prevalence of irritable bowel syndrome in adolescents was high, with bullying, female gender, age 14–16 years, constipation and diarrhea, and dietary consumption of soft drinks, coffee, and tea as risk factors. A significant association with intestinal inflammation was found. © 2020 Sociedade Brasileira de Pediatria	Adolescent; Intestinal integrity; Irritable bowel syndrome; Quality of life	alpha 1 antitrypsin; calgranulin; adolescent; adult; age; Article; avoidance behavior; body image; bullying; clinical evaluation; coffee consumption; comparative study; constipation; controlled study; cross-sectional study; data analysis software; diarrhea; digestive system disease assessment; disease association; dysphoria; enteritis; feces level; female; gender; high school; human; human activities; human relation; Indonesia; Indonesian; intestine mucosa; Irritable Bowel Syndrome Quality of Life questionnaire; irritable colon; major clinical study; male; nut; patient worry; pediatric patient; prevalence; quality of life; quality of life assessment; risk factor; Rome III criteria; sexual behavior; social behavior; soft drink; tea consumption; constipation; irritable colon; questionnaire;	Elsevier Editora Ltda	00217557	32156535	Article	Q2	645	7804	View
September 2021(1)
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679	Akbar R., George Y., Madjid A.S., Sedono R., Tantri A.	57317624300;26027840300;57163353500;56660590500;57188933853;	Early administration of norepinephrine prevents the occurrence of fluid overload in the resuscitation of septic shock patients	2021	Critical Care and Shock	September 2021			257	268		https://www.scopus.com/inward/record.uri?eid=2-s2.0-85118270800&partnerID=40&md5=d27a72a8961cf30e6da6e5952895aa23	Trainee of Intensive Care Fellowship Program, University of Indonesia-Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Medical Faculty, Haluoleo University-Konawe General Hos-pital, Konawe, Indonesia; Emergency and Intensive Care Unit-Pondok Indah Hospital Jakarta and Departement of Anesthesiology and Intensive Therapy-Faculty of Medicine Universitas, Indonesia; Department of Anesthesiology and Intensive Care, Cipto Mangunkusumo Hospital, University of Indonesia, Jakarta, Indonesia	Akbar, R., Trainee of Intensive Care Fellowship Program, University of Indonesia-Cipto Mangunkusumo Hospital, Jakarta, Indonesia, Medical Faculty, Haluoleo University-Konawe General Hos-pital, Konawe, Indonesia; George, Y., Emergency and Intensive Care Unit-Pondok Indah Hospital Jakarta and Departement of Anesthesiology and Intensive Therapy-Faculty of Medicine Universitas, Indonesia; Madjid, A.S., Department of Anesthesiology and Intensive Care, Cipto Mangunkusumo Hospital, University of Indonesia, Jakarta, Indonesia; Sedono, R., Department of Anesthesiology and Intensive Care, Cipto Mangunkusumo Hospital, University of Indonesia, Jakarta, Indonesia; Tantri, A., Department of Anesthesiology and Intensive Care, Cipto Mangunkusumo Hospital, University of Indonesia, Jakarta, Indonesia	Background: Critically ill patients with sepsis usually receive a very large volume of fluids cau-sing a very significant positive fluid balance in an effort to meet the needs of cardiac output, syste-mic blood pressure, and perfusion to the kidneys. This condition also tends to be associated with poor survival rates. The aim of this study was to determine whether early maintenance of norepi-nephrine can reduce fluid administration and prevent overload in the resuscitation of patients with septic shock. Methods: This study was a randomized, non-blind clinical trial, of which the subjects were adult patients with septic shock admitted to the intensive and emergency care unit from January to November 2020. There were two treatment groups of this study, the early norepinephrine group (NEP group) and the 30 ml/kgBW fluid resuscitation one (Fluid group). The test was con-ducted on the urinary albumin-to-creatinine ra-tio, increase of serum creatinine value, ratio of arterial oxygen partial pressure to fractional in-spired oxygen (PaO2/FiO2 ratio), and intra-ab-dominal pressure at the time of septic shock di-agnosis was established, 3 hours, and 24 hours . after the treatment was given. The data was pro-cessed using the SPSS device. Results: Based on the analysis, it was found that there were significant differences in all study va-riables of the Fluid group compared to the NEP group. The amount of fluid administration in the NEP group averaged 2198.63 ml, less than that in the Fluid group with an average of 3999.30 ml (chi square test p=0.000). By comparing the measurement results to the initial measurement values in the two groups, the fluid overload was high-risk in the Fluid group. There was a significant relationship between the urinary albumin-to-creatinine ratio (OR=48.273; 95% CI=16.708-139.472), the increase in serum crea-tinine value (OR=73.381; 95% CI=19.955-269.849), the low PaO2/FiO2 ratio (OR=12.225; 95% CI=5.290-28.252), and the increase in intra-abdominal pressure (OR=32.667; 95% CI=10.490-101.724) with the provision of 30 ml/kgBW fluid resuscitation, which indicated the risk of fluid overload. Conclusion: Early norepinephrine administration can reduce fluid administration and prevent overload in the resuscitation of patients with septic shock. © 2021, The Indonesian Foundation of Critical Care Medicine. All rights reserved.	Early norepinephrine; Fluid overload; Septic shock	noradrenalin; abdominal pressure; adult; aged; albumin to creatinine ratio; albuminuria; Article; blood volume; capillary leak syndrome; controlled study; creatinine blood level; emergency care; female; fraction of inspired oxygen; Horowitz index; human; hypervolemia; intensive care; major clinical study; male; randomized controlled trial; resuscitation; risk; septic shock; Sequential Organ Failure Assessment Score; systolic blood pressure	The Indonesian Foundation of Critical Care Medicine	14107767		Article	Q4	134	24890	View

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