Publikasi Scopus 2024 per tanggal 31 Juli 2024 (607 artikel)

Julian J.; Adawiyah R.; Wahdini S.
Julian, Julian (58677322900); Adawiyah, Robiatul (57208658742); Wahdini, Sri (57203684068)
58677322900; 57208658742; 57203684068
BIOMOLECULAR ACTIVITY OF CRYPTOCOCCUS DURING CRYPTOCOCCOSIS: A REVIEW OF MOLECULAR INTERACTIONS OF CRYPTOCOCCUS WITH HUMAN IMMUNE SYSTEM AND BLOOD-BRAIN-BARRIER
2024
African Journal of Infectious Diseases
18
1
11
22
11
0
Master‟s Programme in biomedical science, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Department of Parasitology, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia
Julian J., Master‟s Programme in biomedical science, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Adawiyah R., Master‟s Programme in biomedical science, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia, Department of Parasitology, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Wahdini S., Department of Parasitology, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia
Global mycosis is still a problem. One of these is the cryptococcal disease. A systemic mycosis brought on by Cryptococcus is called cryptococcosis. Host immunological conditions influence infection with Cryptococcosis. When environmental spores are inhaled by the host, the spores get to the lungs, an infection is created. Alveolar macrophages and other immune cells recognize Cryptococcus in the lung. The initial line of defense against pathogens in the phagolysosome is provided by alveolar macrophages found in the lungs. When the immune system is weak, Cryptococcus uses the evasion system as a molecular interaction with the immune system and persists in the lungs without causing any symptoms such as Factor Transcription, Cell masking, N-glycan structure, Extracellular molecule, and Antioxidant system. The evasion mechanism protects and makes Cryptococcus disseminate throughout the other organs, especially CNS. If Cryptococcus escapes against the host immune system, it will disseminate to other organs, especially Cerebrospinal System by Three mechanisms. There are Trojan Horse, Paracellular, and Transcellular interactions with Blood-Brain Barrier. Disease severity is determined by the Interaction between the host‟s immune system and the fungus. © 2024, African Traditional, Herbal Medicine Supporters Initiative. All rights reserved.
Biomolecular Activity; Blood-Brain-Barrier; Cryptococcus; Fungal Disease; Immune Response
fibrinogen; gamma interferon; glycan; Hermes antigen; interleukin 13; interleukin 1beta; nitric oxide; pathogen associated molecular pattern; reactive oxygen metabolite; toll like receptor; toll like receptor 4; toll like receptor 9; tumor necrosis factor; antioxidant activity; apoptosis; Article; blood brain barrier; CD4+ T lymphocyte; cryptococcosis; Cryptococcus neoformans; cytokine release; endocytosis; endoplasmic reticulum stress; Filobasidiella; human; immune response; immune system; innate immunity; lung alveolus macrophage; macrophage; molecular interaction; mycosis; nonhuman; oxidative stress; phagocytosis; phagolysosome; Th17 cell
Ministry of Education, Culture, Research and Technology of the Republic of Indonesia, (NKB-0395/UN2.R3.1/HKP.05.00/2019)
This manuscript was supported by “Publikasi Internasional Terindeks Tugas Akhir (PITTA A)” Research Grant 2019 from the Ministry of Education, Culture, Research and Technology of the Republic of Indonesia with grant number NKB-0395/UN2.R3.1/HKP.05.00/2019
African Traditional, Herbal Medicine Supporters Initiative
20060165
Article
Q4
184
20019