Publikasi Scopus 2024 per tanggal 31 Juli 2024 (607 artikel)

Publikasi Scopus 2024 per tanggal 31 Juli 2024 (607 artikel)

Mesinovic M.; Wong X.C.; Rajahram G.S.; Citarella B.W.; Peariasamy K.M.; van Someren Greve F.; Olliaro P.; Merson L.; Clifton L.; Kartsonaki C.; Abdukahil S.A.; Abdulkadir N.N.; Abe R.; Abel L.; Abrous A.; Absil L.; Acker A.; Adachi S.; Adam E.; Adriano E.; Adrião D.; Ageel S.A.; Ahmed S.; Aiello M.; Ainscough K.; Airlangga E.; Aisa T.; Hssain A.A.; Tamlihat Y.A.; Akimoto T.; Akmal E.; Qasim E.A.; Alalqam R.; Alberti A.; Al-dabbous T.; Alegesan S.; Alegre C.; Alessi M.; Alex B.; Alexandre K.; Al-Fares A.; Alfoudri H.; Ali A.; Ali I.; Alidjnou K.E.; Aliudin J.; Alkhafajee Q.; Allavena C.; Allou N.; Alves J.; Alves J.M.; Alves R.; Cabrita J.A.; Amaral M.; Amira N.; Ammerlaan H.; Ampaw P.; Andini R.; Andréjak C.; Angheben A.; Angoulvant F.; Ansart S.; Anthonidass S.; Antonelli M.; de Brito C.A.A.; Anwar K.R.; Apriyana A.; Arabi Y.; Aragao I.; Arancibia F.; Araujo C.; Arcadipane A.; Archambault P.; Arenz L.; Arlet J.-B.; Arnold-Day C.; Arora L.; Arora R.; Artaud-Macari E.; Aryal D.; Asaki M.; Asensio A.; Ashley E.A.; Ashraf M.; Assie J.B.; Asyraf A.; Atique A.; Attanyake A.M.U.L.; Auchabie J.; Aumaitre H.; Auvet A.; Azemar L.; Azoulay C.; Bach B.; Bachelet D.; Badr C.; Baig N.; Baillie J.K.; Baird J.K.; Bak E.; Bakakos A.; Bakar N.A.; Bal A.; Balakrishnan M.; Balan V.; Bani-Sadr F.; Barbalho R.; Barbosa N.Y.; Barclay W.S.; Barnett S.U.; Barnikel M.; Barrasa H.; Barrelet A.; Barrigoto C.; Bartoli M.; Baruch J.; Basmaci R.; Basri M.F.H.; Battaglini D.; Bauer J.; Rincon D.F.B.; Dow D.B.; Beane A.; Bedossa A.; Bee K.H.; Begum H.; Behilill S.; Beishuizen A.; Beljantsev A.; Bellemare D.; Beltrame A.; Beltrão B.A.; Beluze M.; Benech N.; Benjiman L.E.; Benkerrou D.; Bennett S.; Bento L.; Berdal J.-E.; Bergeaud D.; Bergin H.; Bertoli G.; Bertolino L.; Bessis S.; Betz A.; Bevilcaqua S.; Bezulier K.; Bhatt A.; Bhavsar K.; Bianco C.; Bidin F.N.; Singh M.B.; Humaid F.B.; Kamarudin M.N.B.; Bisoffi Z.; Bissuel F.; Biston P.; Bitker L.; Bitton J.; Blanco-Schweizer P.; Blier C.; Bloos F.; Blot M.; Blumberg L.; Boccia F.; Bodenes L.; Bogaert D.; Boivin A.-H.; Bolaños I.; Bolze P.-A.; Bompart F.; Bonelli P.; Bonfasius A.; Borges D.; Borie R.; Bosse H.M.; Botelho-Nevers E.; Bouadma L.; Bouchaud O.; Bouchez S.; Bouhmani D.; Bouhour D.; Bouiller K.; Bouillet L.; Bouisse C.; Bounphiengsy T.; Bountthasavong L.; Boureau A.-S.; Bourke J.; Bouscambert M.; Bousquet A.; Bouziotis J.; Boxma B.; Boyer-Besseyre M.; Boylan M.; Bozza F.A.; Braconnier A.; Braga C.; Brandenburger T.; Monteiro F.B.; Brazzi L.; Breen D.; Breen P.; Brewster D.; Brickell K.; Browne A.; Browne S.; Brozzi N.; Brusse-Keizer M.; Buchtele N.; Bugaeva P.; Buisson M.; Buonsenso D.; Burhan E.; Burrell A.; Bustos I.G.; Butnaru D.; Cabie A.; Cabral S.; Caceres E.; Cadoz C.; Garcês R.C.; Callahan M.; Calligy K.; Calvache J.A.; Caminiti C.; Camões J.; Campana V.; Campbell P.; Campisi J.; Canepa C.; Cantero M.; Caraux-Paz P.; Cárcel S.; Cardellino C.S.; Cardoso F.; Cardoso F.; Cardoso N.; Cardoso S.; Carelli S.; Carlacci F.; Carlier N.; Carmoi T.; Carney G.; Carqueja I.; Carret M.-C.; Carrier F.M.; Carroll I.; Carson G.; Carvalho L.; Casanova M.-L.; Cascão M.; Casey S.; Casimiro J.; Cassandra B.; Castañeda S.; Castanheira N.; Castor-Alexandre G.; Castro I.; Catarino A.; Catherine F.-X.; Cattaneo P.; Cavalin R.; Cavalli G.G.; Cavayas A.; Ceccato A.; Cerkovnik S.; Cervantes-Gonzalez M.; Chair A.; Chakveatze C.; Chaleunphon B.; Chan A.; Chand M.; Auger C.C.; Chapplain J.-M.; Charpentier C.; Chas J.; Chatterjee A.; Iñiguez J.S.C.; Chen A.; Chenard L.; Cheng M.P.; Cheret A.; Chetta A.A.; Chiarabini T.; Chica J.; Chidambaram S.K.; Tho L.C.; Chirouze C.; Chiumello D.; Cho H.J.; Cho S.-M.; Cholley B.; Chommanam D.; Chopin M.-C.; Chow T.S.; Chow Y.P.; Christy N.; Chua H.J.; Chua J.; Cidade J.P.; Herreros J.M.C.; Ciullo A.; Clarke E.; Clarke J.; Granado R.C.-D.; Clohisey S.; Codan C.; Cody C.; Coelho A.; Coles J.; Coles M.; Colin G.; Collins M.; Colombo S.M.; Combs P.; Connor M.; Conrad A.; Contreras S.; Conway E.; Cooke G.S.; Copland M.; Cordel H.; Corley A.; Cornelis S.; Cornet A.D.; Corpuz A.J.; Cortegiani A.; Corvaisier G.; Costigan E.; Couffignal C.; Couffin-Cadiergues S.; Courtois R.; Cousse S.; Cregan R.; D’Orleans C.C.; Cristella C.; Croonen S.; Crowl G.; Crump J.; Cruz C.; Csete M.; Cullen A.; Cummings M.; Curley G.; Curlier E.; Curran C.; Custodio P.; da Silva Filipe A.; Da Silveira C.; Dabaliz A.-A.; Dagens A.; Dahly D.; Dalton H.; Dalton J.; Daly S.; Damas J.; Daneman N.; Daniel C.; Dankwa E.A.; Dantas J.; D’Aragon F.; de Jong M.; de Loughry G.; de Mendoza D.; De Montmollin E.; de Oliveira França R.F.; de Pinho Oliveira A.I.; De Rosa R.; De Rose C.; de Silva T.; de Vries P.; Deacon J.; Dean D.; Debard A.; Debray M.-P.; DeCastro N.; Dechert W.; Deconninck L.; Decours R.; Defous E.; Delacroix I.; Delaveuve E.; Delavigne K.; Delfos N.M.; Deligiannis I.; Dell’Amore A.; Delmas C.; Delobel P.; Delsing C.; Demonchy E.; Denis E.; Deplanque D.; Depuydt P.; Desai M.; Descamps D.; Desvallées M.; Dewayanti S.; Dhanger P.; Diallo A.; Diamantis S.; Dias A.; Dias A.; Da Silva F.D.; Diaz J.J.; Diaz P.; Diaz R.; Didier K.; Diehl J.-L.; Dieperink W.; Dimet J.; Dinot V.; Diop F.; Diouf A.; Dishon Y.; Djossou F.; Docherty A.B.; Doherty H.; Dondorp A.M.; Dong A.; Donnelly C.A.; Donnelly M.; Donohue C.; Donohue S.; Donohue Y.; Doran P.; Dorival C.; D’Ortenzio E.; Douangdala P.; Douglas J.J.; Douma R.; Dournon N.; Downer T.; Downey J.; Downing M.; Drake T.; Driscoll A.; Dryden M.; Fonseca C.D.; Dubee V.; Dubos F.; Dubot-Pérès A.; Ducancelle A.; Duculan T.; Dudman S.; Duggal A.; Dunand P.; Dunning J.; Duplaix M.; Durante-Mangoni E.; Durham L., III; Dussol B.; Duthoit J.; Duval X.; Dyrhol-Riise A.M.; Ean S.C.; Echeverria-Villalobos M.; Economopoulos G.; Egan S.; Eira C.; Sanharawi M.E.; Elapavaluru S.; Elharrar B.; Ellerbroek J.; Eloy P.; Elshazly T.; Elyazar I.; Enderle I.; Endo T.; Eng C.C.; Engelmann I.; Enouf V.; Epaulard O.; Escher M.; Esperatti M.; Esperou H.; Santo C.E.; Esposito-Farese M.; Estevão J.; Etienne M.; Ettalhaoui N.; Everding A.G.; Evers M.; Fabre I.; Fabre M.; Faheem A.; Fahy A.; Fairfield C.J.; Fakar Z.; Faria P.; Fateena H.; Fatoni A.Z.; Faure K.; Favory R.; Fayed M.; Feely N.; Feeney L.; Fernandes J.; Fernandes M.A.; Fernandes S.; Ferrand F.-X.; Devouge E.F.; Ferrão J.; Ferrari C.; Ferraz M.; Ferreira B.; Ferreira B.; Ferreira I.; Ferreira S.; Ferrer-Roca R.; Ferriere N.; Ficko C.; Figueiredo-Mello C.; Finlayson W.; Fiorda J.; Flament T.; Flateau C.; Fletcher T.; Florence A.-M.; Florio L.L.; Flynn B.; Flynn D.; Fogliazza F.; Foley C.; Foley J.; Fomin V.; Fonseca T.; Fontela P.; Forsyth S.; Foster D.; Foti G.; Fourn E.; Fowler R.A.; Fraher M.; Franch-Llasat D.; Fraser C.; Fraser J.F.; Freire M.V.; Ribeiro A.F.; Friedrich C.; Fritz R.; Fry S.; Fuentes N.; Fukuda M.; G A.; Gaborieau V.; Gaci R.; Gagliardi M.; Gagnard J.-C.; Gagneux-Brunon A.; Gaião S.; Skeie L.G.; Gallagher P.; Curto E.G.; Gamble C.; Gani Y.; Garan A.; Garcia R.; Garcia-Diaz J.; Garcia-Gallo E.; Garimella N.; Garofalo F.; Garot D.; Garrait V.; Gault N.; Gavin A.; Gavrylov A.; Gaymard A.; Gebauer J.; Geraud E.; Morlaes L.G.; Germano N.; ghisulal P.K.; Ghosn J.; Giani M.; Giaquinto C.; Gibson J.; Gigante T.; Gilg M.; Gilroy E.; Giordano G.; Girvan M.; Gissot V.; Glikman D.; Glybochko P.; Gnall E.; Goco G.; Goehringer F.; Goepel S.; Goffard J.-C.; Goh J.Y.; Golob J.; Gomes R.; Gomez K.; Gómez-Junyent J.; Gominet M.; Gonzalez A.; Gordon P.; Gorenne I.; Goubert L.; Goujard C.; Goulenok T.; Grable M.; Graf J.; Grandin E.W.; Granier P.; Grasselli G.; Green C.A.; Greene C.; Greenhalf W.; Greffe S.; Grieco D.L.; Griffee M.; Griffiths F.; Grigoras I.; Groenendijk A.; Lordemann A.G.; Gruner H.; Gu Y.; Guedj J.; Guego M.; Guellec D.; Guerguerian A.-M.; Guerreiro D.; Guery R.; Guillaumot A.; Guilleminault L.; de Castro M.G.; Guimard T.; Haalboom M.; Haber D.; Habraken H.; Hachemi A.; Hadri N.; Hakak S.; Hall A.; Hall M.; Halpin S.; Hamer A.; Hamidfar R.; Hammond N.; Hammond T.; Han L.Y.; Haniffa R.; Hao K.W.; Hardwick H.; Harrison E.M.; Harrison J.; Harrison S.B.E.; Hartman A.; Hashmi J.; Hayes A.; Hays L.; Heerman J.; Heggelund L.; Hendry R.; Hennessy M.; Henriquez-Trujillo A.; Hentzien M.; Hernandez D.; Hernandez-Montfort J.; Hershey A.; Hesstvedt L.; Hidayah A.; Higgins D.; Higgins E.; Higgins R.; Hinchion R.; Hinton S.; Hiraiwa H.; Hirkani H.; Hitoto H.; Ho A.; Ho Y.B.; Hoctin A.; Hoffmann I.; Hoh W.H.; Hoiting O.; Holt R.; Holter J.C.; Horby P.; Horcajada J.P.; Hoshino K.; Hoshino K.; Houas I.; Hough C.L.; Houltham S.; Hsu J.M.-Y.; Hulot J.-S.; Huo S.; Hurd A.; Ijaz S.; Ikram M.A.; Illana C.C.; Illes H.-G.; Imbert P.; Inácio H.; Dominguez C.I.; Ing Y.S.; Iosifidis E.; Ippolito M.; Irawany V.; Isgett S.; Isidoro T.; Ismail N.; Isnard M.; Itai J.; Ito A.; Ivulich D.; Jaafar D.; Jaafoura S.; Jabot J.; Jackson C.; Jamieson N.; Janes V.; Jaquet P.; Jassat W.; Jaud-Fischer C.; Jaureguiberry S.; Javidfar J.; Jaworsky D.; Jego F.; Jelani A.M.; Jenum S.; Jimbo-Sotomayor R.; Joe O.Y.; García R.N.J.; Joseph C.; Joseph M.; Joshi S.; Jourdain M.; Jouvet P.; Jung A.; Jung H.; Juzar D.; Kafif O.; Kaguelidou F.; Kaisbain N.; Kaleesvran T.; Kali S.; Kalicinska A.; Kalomoiri S.; Kamaluddin M.A.A.; Kamaruddin Z.A.C.; Kamarudin N.; Kandamby D.H.; Kandel C.; Kang K.Y.; Karpayah P.; Karsies T.; Kartsonaki C.; Kasugai D.; Kataria A.; Katz K.; Kaur A.; Kay C.; Keane H.; Keating S.; Kedia P.; Kelly A.; Kelly A.; Kelly C.; Kelly N.; Kelly S.; Kelly Y.; Kelsey M.; Kennedy R.; Kennon K.; Keomany S.; Kernan M.; Kerroumi Y.; Keshav S.; Kestelyn E.; Khalid I.; Khalil A.; Khan C.; Khan I.; Kherajani K.; Kho M.E.; Khoo D.; Khoo R.; Khoo S.; Kiat K.H.; Kida Y.; Kiiza P.; Granerud B.K.; Kildal A.B.; Kim J.B.; Kimmoun A.; Kindgen-Milles D.; King A.; Kitamura N.; Klenerman P.; Klont R.; Bekken G.K.; Knight S.R.; Kobbe R.; Kodippily C.; Vasconcelos M.K.; Komatsu M.; Korten I.S.A.R.I.C.C.; Kosgei C.; Kpangon A.; Krawczyk K.; Krishnan S.; Krishnan V.; Kruglova O.; Kumar D.; Kumar G.; Vecham P.K.; Kuriakose D.; Kurtzman E.; Kusumastuti N.P.; Kutsogiannis D.; Kutsyna G.; Kyriakoulis K.; Hamers R.L.; Lachatre M.; Lacoste M.; Laffey J.G.; Lafhej N.; Lagrange M.; Laine F.; Lairez O.; Lambert M.; Lamontagne F.; Langelot-Richard M.; Langlois V.; Lantang E.Y.; Lanza M.; Laouénan C.; Laribi S.; Lariviere D.; Lasry S.; Lath S.; Launay O.; Laureillard D.; Lavie-Badie Y.; Law A.; Lawrence C.; Lawrence T.; Le M.; Bihan C.L.; Bris C.L.; Falher G.L.; Fevre L.L.; Hingrat Q.L.; Maréchal M.L.; Mestre S.L.; Moal G.L.; Moing V.L.; Nagard H.L.; Turnier P.L.; Leal E.; Santos M.L.; Lee B.H.; Lee H.G.; Lee J.; Lee J.; Lee S.H.; Lee T.C.; Lee Y.L.; Leeming G.; Lefebvre B.; Lefebvre L.; Lefèvre B.; LeGac S.; Lelievre J.-D.; Lellouche F.; Lemaignen A.; Lemee V.; Lemeur A.; Lemmink G.; Lene H.S.; Lennon J.; León R.; Leone M.; Leone M.; Lescure F.-X.; Lesens O.; Lesouhaitier M.; Lester-Grant A.; Letizia A.; Letrou S.; Levy B.; Levy Y.; Levy-Marchal C.; Lewandowska K.; L’Her E.; Bassi G.L.; Liang J.; Liegeon G.; Lim K.C.; Lim W.S.; Lima C.; Lina B.; Lina L.; Lind A.; Lingad M.K.; Lingas G.; Lion-Daolio S.; Lissauer S.; Liu K.; Livrozet M.; Lizotte P.; Loforte A.; Lolong N.; Loon L.C.; Lopes D.; Lopez-Colon D.; Lopez-Revilla J.W.; Loschner A.L.; Loubet P.; Loufti B.; Louis G.; Lourenco S.; Lovelace-Macon L.; Low L.L.; Lowik M.; Loy J.S.; Lucet J.C.; Luna C.M.; Lungu O.; Luong L.; Luque N.; Luton D.; Lwin N.; Lyons R.; Maasikas O.; Mabiala O.; Machado M.; Machado S.; Macheda G.; Madiha H.; Maglietta G.; Mahieu R.; Mahy S.; Maia A.R.; Maier L.S.; Maillet M.; Maitre T.; Majori M.; Malfertheiner M.; Malik N.; Mallon P.; Maltez F.; Malvy D.; Mammi P.; Manda V.; Mandei J.M.; Mandelbrot L.; Manetta F.; Mankikian J.; Manning E.; Manuel A.; Malaque C.M.S.; Marino D.; Marino F.; Markowicz S.; Marques A.; Marquis C.; Marsh B.; Marshal M.; Marshall J.; Martelli C.T.; Martin D.-A.; Martin E.; Martin-Blondel G.; Martin-Loeches I.; Martinot M.; Martín-Quiros A.; Martinez F.E.; Martins A.; Martins J.; Martins N.; Rego C.M.; Martucci G.; Martynenko O.; Marwali E.M.; Marzukie M.; Jimenez J.F.M.; Maslove D.; Mason S.; Nor B.M.; Matan M.; Mathieu D.; Mattei M.; Matulevics R.; Maulin L.; Maxwell M.; Maynar J.; Mayxay M.; Mazzoni T.; Sweeney L.M.; McCanny P.; McArthur C.; McCarthy A.; McCarthy A.; McCloskey C.; McConnochie R.; McDermott S.; McDonald S.E.; McElroy A.; McElwee S.; McEneany V.; McEvoy N.; McGeer A.; McKay C.; McKeown J.; McLean K.A.; McNally P.; McNicholas B.; McPartlan E.; Meaney E.; Mear-Passard C.; Mechlin M.; Mehkri O.; Mele F.; Melo L.; Mendes J.J.; Menkiti O.; Menon K.; Mentré F.; Mentzer A.J.; Mercier E.
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At-admission prediction of mortality and pulmonary embolism in an international cohort of hospitalised patients with COVID-19 using statistical and machine learning methods
2024
Scientific Reports
14
1
16387
0
https://www.scopus.com/inward/record.uri?eid=2-s2.0-85199015852&doi=10.1038%2fs41598-024-63212-7&partnerID=40&md5=4d554452fe539661a722382eae0ac9e8
Department of Engineering Science, University of Oxford, Oxford, United Kingdom; Digital Health Research and Innovation Unit, Institute for Clinical Research, National Institutes of Health (NIH), Shah Alam, Malaysia; Queen Elizabeth II Hospital, Ministry of Health, Kota Kinabalu, Malaysia; Pandemic Sciences Institute, ISARIC, University of Oxford, Oxford, United Kingdom; Department of Medical Microbiology, Amsterdam University Medical Center, Amsterdam, Netherlands; Nuffield Department of Population Health, University of Oxford, Oxford, United Kingdom; King Abdulaziz Medical City, Riyadh, Saudi Arabia; Tuanku Fauziah Hospital, Perlis, Malaysia; Chiba University Hospital, Chiba, Japan; INSERM, Paris, France; CUB-Hopital Erasme, Anderlecht, Belgium; Perelman School of Medicine, University of Pennsylvania, Philadelphia, United States; Rinku General Medical Center, Osaka, Japan; Uniklinik University Hospital, Frankfurt, Germany; University Hospital of Parma, Parma, Italy; Centro Hospitalar Vila Nova de Gaia/Espinho, Espinho, Portugal; King Faisal Hospital Research Center, Riyadh, Saudi Arabia; University Hospital, Kerry, Ireland; St Vincents University Hospital, Dublin, Ireland; Murni Teguh Memorial Hospital, Bunda Thamrin Hospital, North Sumatera, Indonesia; Our lady of Lourdes Drogheda, Drogheda, Ireland; Hamad General Hospital, Doha, Qatar; Centre Hospitalier de Saintonge, Saintes, France; Teine Keijinkai Hospital, Sapporo, Japan; Persahabatan Hospital, Jakarta, Indonesia; Beaumont Hospital, Dublin, Ireland; Northwell Health, NY, United States; Al-Adan Hospital, Hadiya, Kuwait; Galway University Hospital, Galway, Ireland; Hospital Vall d’Hebron, Barcelona, Spain; University Hospital Policlinico Paolo Giaccone, Palermo, Italy; School of Informatics, University of Edinburgh, Edinburgh, United Kingdom; Centre Hospitalier Universitaire Rouen (Center Hospitalier Universitaire de Rouen), Rouen, France; Al-Amiri & amp; Jaber Al-Ahmed Hospitals, Kuwait City, Kuwait; St Bernard’s Hospital, Gibraltar, Gibraltar; Sligo University Hospital (Saolta), Sligo, Ireland; Centre Hospitalier Universitaire de Lille, Lille, France; Centre Hospitalier Universitaire de Nantes (Hôpital femme-enfant-adolescent), Nantes, France; Centre Hospitalier Félix-Guyon, Saint-Denis, Reunion; Centro Hospital e Universitário de Coimbra, Coimbra, Portugal; Hospital de São José -U.U.M, Lisbon, Portugal; Hospital Curry Cabral - Intensive Care Unit - UCIP7, Lisbon, Portugal; Sungai Buloh Hospital, Selangor, Malaysia; Catharina Ziekenhuis, Eindhoven, Netherlands; The Ottawa Hospital, Ottawa, Canada; University of Campania, Carseta, Italy; Centre Hospitalier Universitaire Amiens-Picardie, Amiens, France; Department of Infectious - Tropical Diseases and Microbiology, IRCCS Sacro Cuore Hospital - Negrar, Negrar di Valpolicella, Italy; Centre Hospitalier Universitaire de Brest, Brest, France; Kuala Lumpur Hospital, WPKL, Kuala Lumpur, Malaysia; Fondazione Policlinico Universitario Agostino Gemelli IRCCS, Rome, Italy; Centro de Pesquisa Aggeu Magalhães, Recife, Fiocruz, Brazil; NICVD Dhaka, Dhaka, Bangladesh; National Cardiovascular Center Harapan Kita Jakarta Indonesia, Jakarta, Indonesia; Intensive Care Department, Ministry of National Guard Health Affairs, Riyadh, Saudi Arabia; Centro Hospitalar Universitário do Porto (CHUP), Porto, Portugal; Instituto Nacional Del Tórax, Santiago, Chile; Istituto Mediterraneo per i Trapianti e Terapie ad Alta Specializzazione, Palermo, Italy; CISSS Chaudière-Appalaches, Quèbec, Canada; Medical Department II, LMU Hospital Munich, Campus Großhadern, Munich, Germany; Hôpital Européen Georges-Pompidou AP-HP, Paris, France; Groote Schuur Hospital, Cape Town, South Africa; University of Iowa, Iowa City, United States; St. Boniface Hospital, Winnipeg, MB, Canada; CCA Network, Asia, Chiang Mai, Thailand; Fujieda Municipal General Hospital, Fujieda, Japan; Hospital Puerta de Hierro Majadahonda, Madrid, Spain; Lao-Oxford-Mahosot Hospital-Wellcome Trust Research Unit, Laos, Vientiane, Thailand; Centre Hospitalier intercommunal de Créteil, Créteil, France; McGill University Health Centre, Montreal, Canada; Centre Hospitalier de Cholet, Cholet, France; Centre Hospitalier de Perpignan, Perpignan, France; Hôpital Lariboisière AP-HP, Paris, France; Hôpital Cochin AP-HP, Paris, France; Centre Hospitalier Intercommunal Villeneuve-Saint-Georges, Villeneuve-Saint-Georges, France; Grande Prairie Queen Elizabeth II, Grande Prairie, Canada; Roslin Institute, University of Edinburgh, Edinburgh, United Kingdom; Rush University Medical Center, Chicago, United States; Sotiria General Hospital, Athens, Greece; Unidade Local de Saúde de Alto Minho, Viana Do Castelo, Portugal; Centre Hospitalier Universitaire de Reims, Reims, France; Instituto de Infectologia Emílio Ribas, Sao Paulo, Brazil; Caja Nacional De Salud, Trinidad, Bolivia; Section of Molecular Virology, Imperial College London, London, United Kingdom; Hospital Universitario de Alava, Araba, Spain; Grand Hôpital de l’Est Francilien (Site de Marne-la-Vallée), Jossigny, France; San Martino Hospital, Genoa, Italy; Clinica Valle de Lilli, Valle del Cauca, Colombia; University of Washington Medical Center - Northwest, Seattle, United States; Critical Care Asia, Bangkok, Thailand; Raja Permaisuri Bainun Hospital, Perak, Malaysia; WHO-ISARIC Clinical Characterisation Protocol & amp; SPRINT-SARI, London, United Kingdom; Medisch Spectrum Twente, Zutphen, Netherlands; Tartu University Hospital, Tartu, Estonia; Hôpital de l’Enfant-Jésus, Quebec, QC, Canada; Follow Up Study Working Group, London, United Kingdom; Sao Camilo Cura D’ars, Fortaleza, Brazil; Centre Hospitalier Universitaire de Lyon - HCL, Lyon, France; Sarawak General Hospital, Sarawak, Malaysia; University of Cincinnati, Cincinnati, United States; Akershus University Hospital, Nordbyhagen, Norway; Ospedale Sacro Cuore Don Calabria, Negrar Di Valpolicella, Italy; Hôpital Raymond-Poincaré, Garches, France; Oklahoma Heart Institute, Oklahoma, United States; Centre Hospitalier Régional et Universitaire de Nancy - Hôpitaux de Brabois, Nancy, France; Hôpital de la Timone, Marseille, France; Ohio State University, Columbus, United States; All India Institute of Medical Sciences, Rishikesh, India; Department of Infectious, Tropical Diseases and Microbiology, IRCCS Sacro Cuore Don Calabria Hospital, Negrar, Italy; Thonon-les-Bains, Thonon-les-Bains, France; Civil Hospital Marie Curie, Charleroi, Belgium; Hôpital Lyon Sud - HCL, Lyon, France; The Centre hospitalier universitaire Sainte-Justine, Montreal, Canada; Rio Hortega University Hospital, Valladolid, Spain; Jena University Hospital, Jena, Germany; Centre Hospitalier Universitaire Mitterrand Dijon-Bourgogne, Dijon, France; National Institute for Communicable Diseases, Johannesburg, South Africa; Centre for Inflammation Research, The Queen’s Medical Research Institute, University of Edinburgh, 47 Little France Crescent, Edinburgh, United Kingdom; Centre Hospitalier de Dax - Côte d’Argent, Dax, France; Universidad del Cauca, Cauca, Colombia; Pratama Rada Bolo Hospital, Karitas Hospital and Waikabubak Hospital, Sumba, Indonesia; Hôpital Bichat Claude-Bernard AP-HP, Paris, France; University Hospital Dusseldorf, Dusseldorf, Germany; Centre Hospitalier Universitaire de Saint-Étienne, Saint-Étienne, France; Hôpital Avicenne, Bobigny, France; Centre hospitalier de l’université de Montréal, Montreal, Canada; Centre Hospitalier de Bourg-en-Bresse, Bourg-en-Bresse, France; Centre Hospitalier Universitaire de Besançon, Besançon, France; Centre Hospitalier Universitaire Grenoble-Alpes, Grenoble, France; Luang Namtha Provincial Hospital, Luang Namtha, Laos; Xieng Khouang Provincial Hospital, Phonsavan, Laos; Centre Hospitalier Universitaire de Nantes (Hôtel-Dieu), Nantes, France; Hôpital d’Instruction des Armées Bégin, Saint-Mandé, France; Franciscus Gasthuis, Rotterdam, Netherlands; Ministry of Health, and D’Or Institute of Research and Education (IDOR), National Institute of Infectious Disease Evandro Chagas, Oswaldo Cruz Foundation (INI-FIOCRUZ), Rio de Janeiro, Brazil; Centre Hospitalier de Mayotte, Mamoudzou, Mayotte; Hospital Egas Moniz, Lisboa, Portugal; Ospedale Molinette, Torino, Italy; Cork University Hospital, Cork, Ireland; Beacon Hospital, Dublin, Ireland; Monash University, Melbourne, Australia; Nelson Hospital, Nelson, New Zealand; Cleveland Clinic, Weston, United States; Medical University of Vienna, Vienna, Austria; Sechenov University, Moscow, Russian Federation; Clinica Universidad de La Sabana, Chia, Cundinamarca, Colombia; Centre Hospitalier Universitaire de Martinique, Fort-de-France, Saint Martin, France; Centre Hospitalier Régional Metz-Thionville, Metz, France; Emory University Healthcare System, Atlanta, United States; Johns Hopkins, Baltimore, United States; Comissão de Ética, Unidade Local de Saúde de Matosinhos, Porto, Portugal; Presbyterian Hospital Services, Alberquerque, United States; Hospital del Mar, Barcelona, Spain; Reina Sofia University Hospital, Cordoba, Spain; Hospital Espírito Santo de Évora, Évora, Portugal; Hôpital Américain de Paris, Neuilly-sur-Seine, France; Vancouver Island Health, Vancouver, Canada; Centre Hospitalier Métropole Savoie, Chambéry, France; Department of Anesthesiology, Centre hospitalier de l’Université de Montréal, Montreal, United States; University Hospital - Limerick, Limerick, Ireland; Centro Hospitalar e Universitário de Coimbra - Hospital Pediátrico, Coimbra, Portugal; Centre Hospitalier de Béziers, Béziers, France; Hospital São Francisco Xavier, Lisbon, Portugal; Policlinicodi Orsola Universitàdi Bologna, Bologna, Italy; Hospital du Sacre Coeur, Montreal, Canada; Hospital Universitari Sagrat Cor, Barcelona, Spain; Avera McKennan Hospital, Sioux Falls, United States; Centre Hospitalier de Melun, Melun, France; Attapeu Provincial Hospital, Attapeu, Laos; Sunnybrook Health Sciences Centre, Toronto, Canada; Antimicrobial Resistance and Hospital Acquired Infection Department, Public Health England, London, United Kingdom; Hôpital Kremlin-Bicêtre, Le Kremlin-Bicêtre, France; Centre Hospitalier Universitaire Rennes (Hôpital Pontchaillou), Rennes, France; Hôpital Tenon AP-HP, Paris, France; University of Guadalajara Health Sciences Center, Guadalajara, Mexico; Höpital Saint-Antoine AP-HP, Paris, France; National Institutes of Health (NIH), Ministry of Health Malaysia, Setia Alam, Malaysia; Ospedale San Paolo, Milan, Italy; Chonnam National University Hospital, Dong-gu, South Korea; Salavan Provincial Hospital, Salavan, Laos; Pulau Pinang Hospital, Pulau Pinang, Malaysia; Sunway Medical Centre, Selangor, Malaysia; University Hospital Virgen del Rocío / Institute of Biomedicine of Seville, Seville, Spain; University of Utah, Salt Lake City, United States; Children’s Health Ireland, Dublin, Ireland; Roslin Institute, University of Edinburgh, Easter Bush, Edinburgh, United Kingdom; Foothills Medical Centre, Calgary, Canada; Connolly Hospital Blanchardstown, Dublin, Ireland; Carilion Clinic, Roanoke, United States; Centre Hospitalier Départemental Vendée, La Roche-sur-Yon, France; Allegheny General Hospital, Pittsburgh, United States; Fondazione IRCCS Ca, Milan, Italy; University of Chicago, Chicago, United States; Liverpool Clinical Trials Centre, University of Liverpool, Liverpool, United Kingdom; Department of Infectious Disease, Imperial College London, London, United Kingdom; Brantford General Hospital, Brantford, Canada; University of Queensland, Brisbane, Australia; Centre Hospitalier Bretagne Atlantique, Vannes, France; Hôpital Jacques Monod, Le Havre, France; PREPARE and RECOVER EU Consortium, Brussels, Belgium; Tergooi Hospital, Hilversum, Netherlands; Michael Garron Hospital, Toronto, Canada; Hospital de Curry Cabral - Infectious Diseases, Lisbon, Portugal; Mount Sinai Medical Center, Miami, FL, United States; Columbia University, New York, United States; Centre Hospitalier Universitaire de Guadeloupe, Pointe-à-Pitre, Guadeloupe; MRC-University of Glasgow Centre for Virus Research, 464 Bearsden Road, Glasgow, United Kingdom; UH Cleveland Hospital, Cleveland, United States; University Hospital - Waterford, Waterford, Ireland; Saint-Martin, Saint-Martin, Guadeloupe; Department of Statistics, University of Oxford, Oxford, United Kingdom; Centre hospitalier Universitaire de Sherbrooke, Sherbrooke, Canada; Centro Hospitalar de Tondela-Viseu, Viseu, Portugal; Monaldi Hospital, Napoli, Italy; Università Cattolica del Sacro Cuore, Rome, Italy; Department of Infection, Immunity and Cardiovascular Disease, The Florey Institute for Host-Pathogen Interactions, University of Sheffield, Sheffield, United Kingdom; St Christopher’s Hospital for Children, Philadelphia, United States; Piedmont Atlanta Hospital, Atlanta, GA, United States; Hôpital Purpan, Toulouse, France; Hôpital Saint-Louis AP-HP, Paris, France; Centre Hospitalier Emile Roux, Le Puy-en-Velay, France; Hôpital Bel-Air, Thionville, France; Centre Hospitalier Universitaire Toulouse (IUCT), Toulouse, France; Alrijne Hospital, Leiden, Netherlands; Policlinico of Padova, Padova, Italy; Centre Hospitalier Universitaire de Nice (Hôpital Archet), Nice, France; ISARIC Global Support Centre, Oxford, United Kingdom; Universitair Ziekenhuis, Gent, Belgium; INOVA Fairfax Medical Center, Fairfax, VA, United States; Hospital Universitario Dr Negrín, Las Palmas, Spain; Hospital Professor Doutor Fernando Fonseca, Amadora, Portugal; Clinica Las Condes, Santiago, Chile; University Medical Center Groningen, Groningen, Netherlands; Centre Hospitalier Mont-de-Marsan, Mont-de-Marsan, France; Rambam Hospital, Haifa, Israel; Centre Hospitalier Andrée Rosemon, Cayenne, French Guiana; Centre for Medical Informatics, The Usher Institute, University of Edinburgh, Edinburgh, United Kingdom; Tallaght University Hospital, Dublin, Ireland; Lions Gate Hospital, Vancouver, Canada; Flevoziekenhuis, Almere, Netherlands; St James’s Hospital, Dublin, Ireland; St Joseph’s Health Center, Sherbrooke, Canada; Centre Hospitalier Universitaire d’Angers, Angers, France; Houston Methodist Hospital, Houston, TX, United States; Oslo University Hospital, Oslo, Norway; Cleveland Clinic, Ohio, OH, United States; Medical College of Wisconsin, WI, United States; Hôpital de la Conception, Marseille, France; Centre Hospitalier de Tourcoing, Tourcoing, France; Centre Hospitalier De Chateaudun, Route De Jallans, Chateaudun, 28200, France; Reinier de Graaf Gasthuis, Delft, Netherlands; Centre Hospitalier Universitaire Rennes (Hôpital Sud), Rennes, France; Tohoku Medical and Pharmaceutical University, Sendai, Japan; Plata Medical Foundation Private Community Hospital, Mar Del, Plata, Argentina; Hospitales Puerta de Hierro, Jalisco, Mexico; Canisius Wilhelmina Ziekenhuis, Nijmenjen, Netherlands; Centre Hospitalier Pierre Oudot, Bourgoin-Jallieu, France; North York General Hospital, Toronto, Canada; Hospital Universiti Sains Malaysia (Mix medical surgical ICU), Kota Bharu, Malaysia; Adult ICU Saiful Anwar Hospital, Malang, Indonesia; University of California San Francisco - Fresno, Fresno, United States; Hospital Santa Maria, Centro Hospitalar Universitário Lisboa Norte, Amadora, Portugal; Centre Hospitalier Techer, Calais, France; Centre Hospitalier Régional et Universitaire de Tours, Tours, France; Liverpool School of Tropical Medicine, Liverpool, United Kingdom; University of Kansas Medical Center, KS, United States; The Montreal Children’s Hospital, Montreal, Canada; Vancouver General Hospital, Vancouver, Canada; Ospedale San Gerardo, Monza, Italy; Hôpital Foch, Suresnes, France; Interdepartmental Division of Critical Care Medicine, University of Toronto, Toronto, Canada; Bon Secours Hospital, Cork, Ireland; Hospital Verge de la Cinta, Tortosa, Spain; Hospital Escola da Universidade Federal de Pelotas, Pelotas, Brazil; Hôpital Albert Calmette, Lille, France; Saiseikai Senri Hospital, Tochigi, Japan; Manipal Hospital Whitefield, Bangalore, India; Centre Hospitalier de Pau, Pau, France; Hôpital privé d’Antony, Antony, France; São João Hospital Centre, Porto, Portugal; San Pedro de Alcantara Hospital, Cáceres, Spain; Beth Israel Deaconess Medical Center, Boston, United States; Ochsner Clinic Foundation, New Orleans, United States; Department of Internal Medicine No2, Lugansk State Medical University, Lugansk, Ukraine; Klinikum Passau, Germant, Germany; Cleveland Clinic Abu Dhabi, Abu Dhabi, United Arab Emirates; University of Padua, Padua, Italy; Children’s Hospital of Eastern Ontario, Ottawa, Canada; Mater Misericordiae University, Dublin, Ireland; Centre Hospitalier Henri Duffaut, Avignon, France; The Baruch Padeh Medical Center Poriya, Tiberias, Israel; Lankenau Institute of Medical Research, Wynnewood, United States; The Hospital for Sick Children (SickKids), Toronto, Canada; University Hospital of Tubingen, Tubingen, Germany; CUB-Hôpital Erasme, Anderlecht, Belgium; Permai Hospital, Johor, Malaysia; Schools of Medicine, University of Michigan, Ann Arbor, United States; Hospital Garcia de Orta, Almada, Portugal; Department of Infectious Diseases, Institut Hospital del Mar d’Investigacions Mèdiques (IMIM), Infectious Pathology and Antimicrobial Research Group (IPAR), Hospital del Mar, Universitat Autònoma de Barcelona (UAB), CEXS-Universitat Pompeu Fabra, Barcelona, Spain; Wexford General Hospital, Wexford, Ireland; Baylor Scott, Dallas, United States; Clinica Alemana DeSantiago, Santiago, Chile; Centre Hospitalier du Pays d’Aix, Aix-en-Provence, France; Institute of Microbiology and Infection, University of Birmingham, Birmingham, United Kingdom; Department of Molecular and Clinical Cancer Medicine, University of Liverpool, Liverpool, United Kingdom; Centre Hospitalier Universitaire Ambroise-Paré, Boulogne-Billancourt, France; Roslin Institute, University of Edinburgh, Easter Bush, Edinburgh, EH25 9RG, United Kingdom; Grigore T, Popa University of Medicine and Pharmacy, Bucharest, Romania; Erasmus Medical Centre, Rotterdam, Netherlands; University Children’s Hospital, University Medical Center Hamburg-Eppendorf, Hamburg, Germany; Hospital de Curry Cabral - Internal Medicine, Lisbon, Portugal; Centre Hospitalier Universitaire Toulouse (Larrey), Toulouse, France; Hospital de Amor, Sao Paulo, Brazil; Middlemore Hospital (Canties Manukan Health), Otahuhu, New Zealand; Centre Hospitalier de Soissons, Soissons, France; Red Deer Regional Hospital, Red Deer, Canada; Big Data Institute, Department of Medicine, University of Oxford, Nuffield, Oxford, United Kingdom; McLeod Healthcare System, Florence, United States; Providence Saint John’s Health Centre, Santa Monica, United States; Kluang Hospital, Johor, Malaysia; Institute of Infection, Veterinary and Ecological Sciences, Faculty of Health and Life Sciences, NIHR Health Protection Research Unit, University of Liverpool, Liverpool, United Kingdom; Kintampo Health Research Centre, Kintampo, Ghana; AZ Maria Middelares, Gent, Belgium; Drammen Hospital, Drammen, Norway; Universidad de Las Américas, Quito, Ecuador; Lancaster General Health, PA, United States; PICU Saiful Anwar Hospital, Malang, Indonesia; Nagoya University Hospital, Nagoya, Japan; Long COVID India - Terna Specialty Hospital and Research Centre, Mumbai, India; Centre Hospitalier Le Mans, Le Mans, France; Medical Research Council, University of Glasgow Centre for Virus Research, Glasgow, United Kingdom; Sultanah Bahiyah Hospital, Kedah, Malaysia; Tuanku Ja’afar, Negeri Sembilan, Seremban, Malaysia; University of Alabama at Birmingham Hospital, Birmingham, United States; Hokkaido University Hospital, Hokkaido, Japan; Fukuoka University, Fukuoka, Japan; US NHLBI PETAL Network, Boston, United States; University of California - San Francisco (UCSF), San Francisco, United States; St. Joseph’s Healthcare Hamilton, Hamilton, Canada; Virology Reference Department, National Infection Service, Public Health England, Colindale Avenue, London, United Kingdom; La Paz Hospital, Madrid, Spain; Centre Hospitalier Annecy Genevois, Annecy, France; Hippokration Hospital, Thessaloniki, Greece; RSUP Fatmawati, South Jakarta, Indonesia; Hiroshima University, Hiroshima, Japan; Mie University Hospital, Tsu, Japan; Hospital Aleman, Buenos Aires, Argentina; Oxford University (ISARIC4C), Oxford, United Kingdom; Mills Memorial Hospital, Terrace, Canada; Raja Perempuan Zainab II Hospital, Kelantan, Malaysia; Hospital Nuestra Señora de Gracia, Zaragoza, Spain; Kyungpook National University Hospital, Daegu, South Korea; Consortium IMGEN, Piaseczno, Poland; Tawau Hospital, Sabah, Malaysia; Melaka Hospital, Melaka, Malaysia; Princess Margaret Hospital, Kwai Hung, China; Nationwide Children’s Hospital, Columbus, United States; Washington University in St. Louis, St Louis, MO, United States; Intensive Care Unit, Royal Infirmary Edinburgh, Edinburgh, United Kingdom; University of Oklahoma Health Sciences Center, Oklahoma, United States; Groupe Hospitalier Diaconesses Croix Saint-Simon, Paris, France; Hospital for Tropical Diseases, Ho Chi Minh City, Viet Nam; Unity Health Toronto, Toronto, Canada; McMaster University, Hamilton, Canada; Lahad Datu Hospital, Sabah, Malaysia; Department of Pharmacology, University of Liverpool, Liverpool, United Kingdom; University Hospital of North Norway, Tromso, Norway; Keimyung University Dong San Hospital, Daegu, South Korea; Kimitsu Chuo Hospital, Chiba, Japan; Nuffield Department of Medicine, Peter Medawar Building for Pathogen Research, University of Oxford, Oxford, United Kingdom; Obihiro-Kosei General Hospital, Obihiro, Japan; Marmara University Hospital, Istanbul, Turkey; University Health Network, Toronto, Canada; Apollo Hospitals Chennai, Chennai, India; Hartford HealthCare, Hartford, United States; University Airlangga Hospital (Paediatric), Surabaya, Indonesia; Royal Alexandra Hospital, Edmonton, Canada; Centre Hospitalier Alpes-Leman, Contamine-sur-Arve, France; Centre Hospitalier Universitaire Toulouse (Rangueil), Toulouse, France; Prof Dr R. D. Kandou Central Hospital (Adult), Manado, Indonesia; Université de Paris, Paris, France; Centre Hospitalier Universitaire de Nîmes, Nîmes, France; The Roslin Institute, University of Edinburgh, Edinburgh, United Kingdom; Wellington Regional Hospital, Wellington, New Zealand; University of Alberta Adult ICU, Edmonton, Canada; Centre Hospitalier Universitaire de Montpellier, Montpellier, France; Centre Hospitalier Universitaire de Poitiers, Poitiers, France; Queen Elizabeth Hospital, Sabah, Malaysia; Severance Hospital, Seoul, South Korea; Division of Informatics, Imaging and Data Science, School of Health Sciences, Faculty of Biology, Medicine and Health, Centre for Health Informatics, University of Manchester, Manchester Academic Health Science Centre, Manchester, United Kingdom; Hôpital Henri-Mondor, Créteil, France; University Institute of Cardiology and Respirology, Quebec, Canada; Sultanah Nur Zahirah Hospital, Terengganu, Malaysia; Centre Hospitalier Universitaire Gabriel Montpied, Clermont-Ferrand, France; Institute of TB and Lung Diseases, Warsaw, Poland; Waitemata District Health Board, Auckland, New Zealand; Nottingham University Hospitals NHS Trust, Nottingham, United Kingdom; Angeles University Foundation Medical Center, Angeles, Philippines; Malawi-Liverpool Wellcome Trust, Blantyre, Malawi; Saiseikai Utsunomiya Hospital, Tochigi, Japan; University of Florida, Gainesville, United States; Instituto Nacional del Niño San Borja, Lima, Peru; Hospital de Clínicas, Buenos Aires, Argentina; Hospital Emergencia Ate Vitarte, Lima, Peru; Port Macquarie Base Hospital, Port Macquarie, Australia; Klinik und Poliklinik für Innere Medizin II, University Hospital Regensburg, Kiel, Germany; William Osler Health Sciences System - Etobicoke General Hospital, Toronto, Canada; Prof Dr R. D. Kandou Central Hospital (Paediatric), Manado, Indonesia; Hôpital Louis-Mourier, Colombes, France; Hospital Vila Franca de Xira, Lisbon, Portugal; Alberta Children’s Hospital, Calgary, Canada; Department of Intensive Care Medicine, Multidisciplinary Intensive Care Research Organisation (MICRO), St. James’s Hospital, Dublin, Ireland; Centre Hospitalier de Colmar, Colmar, France; Emergency Department. Hospital, Universitario La Paz - IdiPAZ, Madrid, Spain; Kingston Health Sciences Centre, Kingston, Canada; International Islamic University Malaysia Medical Centre (IIUMMC), Pahang, Malaysia; Waikato Hospital, Hamilton, New Zealand; Auckland City Hospital, (DCCM 82), Auckland, New Zealand; Mount Sinai Hospital, Toronto, Canada; London Health Sciences Centre, London, Canada; Wellcome Centre for Human Genetics, University of Oxford, Oxford, United Kingdom; Centre Hospitalier de Cahors, Cahors, France; Institute of Genetics and Molecular Medicine, MRC Human Genetics Unit, MRC, University of Edinburgh, Edinburgh, United Kingdom; Centre Hospitalier Universitaire Rouen (Hôpital Charles Nicolle), Rouen, France; Institute of Infection, Veterinary and Ecological Sciences, University of Liverpool, Liverpool, United Kingdom; Hospital Clinic, Barcelona, Spain; Tengku Ampuan Afzan Hospital, Pahang, Malaysia; Florence Nightingale Faculty of Nursing, Midwifery and Palliative Care, Care for Long Term Conditions Division, King’s College London, London, United Kingdom; Faculty of Medicine, University of British Columbia, Vancouver, Canada; Baystate MC, Springfield, United States; University Hospital Northern British Columbia, Prince George, Canada; St-Pierre University Hospital, Brussels, Belgium; Faculty of Medicine, Universitas Indonesia, Cipto Mangunkusumo Hospital, Kota Depok, Indonesia; Queen Mary Hospital, Pok Fu Lam, China; Hôpital Pellegrin, Bordeaux, France; Irish Critical Care Critical Clinical Trials Network, Ireland, Dublin, United Kingdom; Siriraj Piyamaharajkarun Hospital (SiPH), Bangkok, Thailand; Oregon Health, Salem, United States; Cleveland Clinic, Abu Dhabi, United Arab Emirates; Division of Infection and Immunity, University College London, London, United Kingdom; Department of Children’s Infectious Diseases, Warsaw, Poland; Dr Sardjito Government Hospital (Paediatric), Yogyakarta, Indonesia; RSUD Pasar Minggu, South Jakarta, Indonesia; Mercy Hospital, Cork, Ireland; Legacy Emanuel Medical Center, Portland, United States; Kyung Pook National University Chilgok Hospital, Daegu, South Korea; Department of Emergency and Critical Care Medicine, Graduate School of Biomedical and Health Sciences, Hiroshima University, Hiroshima, Japan; Instituto do Coração da Universidade de São Paulo (INCOR), São Paulo, Brazil; Misericordia Community Hospital, Edmonton, Canada; Department of Medical Microbiology and Infection Control, Franciscus Gasthuis & amp; Vlietland, Rotterdam, Netherlands; Joseph Brant Hospital, Burlington, Canada; National Heart and Lung Institute, Imperial College London, London, United Kingdom; Tufts Medical Centre, Boston, United States; Mayo Clinic School of Medicine, Arizona, United States; All India Institute of Medical Sciences (AIIMS), Rishikesh, India; Hospital General San Francisco, Quito, Ecuador; Auckland City Hospital (CVICU), Auckland, New Zealand; Hospital Beatriz Ângelo, Loures, Portugal; Niagara Health, Niagara, Canada; Centre Hospitalier de Périgueux, Périgueux, France; University Hospital Ostrava, Ostrava-Poruba, Czech Republic; Humber River Hospital, Toronto, Canada; Maastricht University Medical Centre, Maastricht, Netherlands; North Estonia Medical Centre, Tallin, Estonia; RSUD Dr. Soetomo, Surabaya, Indonesia; Baylor University Medical Centre, Dallas, United States; Apollo Hospitals Chennai, Tamil Nadu, Chennai, India; Ministry of Health, and D’Or Institute of Research and Education (IDOR), National Institute of Infectious Disease Evandro Chagas, Oswaldo Cruz Foundation (INI-FIOCRUZ), Rio de Janeiro, Gaspar Viana Pavilion, Brazil; Network for Improving Critical care Systems and Training, Colombo, Sri Lanka; Clinic of Anesthesiology and Intensive Care, North Estonia Medical Centre, Tallinn, Estonia; Hospital de Abrantes - ICU, Abrantes, Portugal; Hôpital Européen Marseille, Marseille, France; Centre Hospitalier Agen-Nérac, Agen, France; Vall d’Hebron Institute of Research, Barcelona, Spain; University of Manitoba, Manitoba, Canada; Universidad de La Sabana, Chia, Colombia; The Center for Diagnosis, Santo Domingo, Dominican Republic; CHU Carémeau, Nimes, France; Royal Melbourne Hospital, Melbourne, Australia; Hôpital Laënnec - site de Quimper, Quimper, France; Fundación Cardiovascular de Colombia, Floridablanca, Colombia; Hospital Universitari Sant Joan D’Alacant, Alicante, Spain; Department of Pediatrics and Virology, St Mary’s Medical School Bldg, Imperial College London, London, United Kingdom; Department of Infectious Diseases I, Carol Davila University of Medicine and Pharmacy, Bucharest, Romania; Centro Hospitalar Universitário do Algarve, Portimão, Portugal; RSPI Prof Dr Sulianti Saroso, Jakarta, Indonesia; The Heart Hospital Baylor Plano, Plano, United States; Gelre Hospitals, Zutphen, Netherlands; Krankenhaus Barmherzige Br, Regensburg, Germany; Baylor AllSaints Medical Centre, Fort Worth, United States; Sozialmedizinisches Zentrum Sud, Vienna, Austria; Institute of Infection, Veterinary and Ecological Sciences, Faculty of Health and Life Sciences, University of Liverpool, Liverpool, United Kingdom; Centro Hospitalar de Leiria, Leiria, Portugal; Institute of Translational Medicine, University of Liverpool, Liverpool, Merseyside, United Kingdom; Tohoku University, Sendai, Japan; Hyogo Prefectural Kakogawa Medical Center, Hyogo, Japan; Tokyo Metropolitan Tama Medical Center, Tokyo, Japan; Pamela Youde Nethersole Eastern Hospital, Chai Wan, China; Grand River Hospital, Kitchener, Canada; Hospital Sungai Buloh, Ministry of Health, Selangor, Malaysia; Seoul National University Bundang Hospital, Seoul, South Korea; Hospital Universitário Clementino Fraga Filho, Rio de Janeiro, Brazil; Baerum Sykehus, Gjettum, Norway; National Institute for Infectious Diseases Matei Bals, Bucharest, Romania; Carol Davila University of Medicine and Pharmacy, Bucharest, Romania; Division of Structural Biology, The Wellcome Centre for Human Genetics, University of Oxford, Headington, Oxford, OX3 7BN, United Kingdom; Sturgeon Community Hospital, St Albert, Canada; Department of Medicine, University of Cambridge, Cambridgeshire, Cambridge, United Kingdom; University Hospital in Krakow, Krakow, Poland; Centre Hospitalier Universitaire Grenoble-Alpes_FU, Grenoble, France; Hospital das Clinicas da Faculdade de Medicina da Universidade de Sao Paulo, Sao Paulo, Brazil; Kyoto Medical Centre, Kyoto, Japan; Yokohama City University Medical Center, Yokohama, Japan; Fatmawati Hospital, Jakarta, Indonesia; Virus Reference Department, National Infection Service, Blood Borne Virus Unit, Public Health England, London, United Kingdom; Complexo Hospitalar Dr. Clementino Fraga, João Pessoa city, Brazil; Centre Hospitalier Louis Raffalli, Manosque, France; University of Nebraska Medical Center, Omaha, United States; Division of Critical Care, University of Cape Town and Groote Schuur Hospital, Cape Town, South Africa; Clínica Internacional, Lima, Peru; Albury Wodonga Health, Albury, Australia; Hôpital Robert-Debré AP-HP, Paris, France; Dunedin Public Hospital, Dunedin, New Zealand; ADRZ, Amsterdam, Netherlands; Meander Medical Centre, Amersfoort, Netherlands; Adrz, Goes, Netherlands; Noordwest-Ziekenhuisgroep, DenHelder, Netherlands; Grey Nun’s Community Hospital, Edmonton, Canada; Beatrix ziekenhuis, Gorinchem, Netherlands; Royal Columbian Hospital, Vancouver, Canada; Department of Intensive Care, Franciscus Gasthuis, Rotterdam, Netherlands; Queen Elizabeth Hospital, Yau Ma Tei, China; Kyoto Prefectural University of Medicine, Kyoto, Japan; Kouritu Tousei Hospital, Seto City, Japan; MedStar Washington Hospital Centre, WA, United States; Clinica Pasteur National - University of Comahue, Neuquén, Argentina; Sultanah Aminah Hospital, Johor, Malaysia; National Infection Service, Public Health England, London, United Kingdom; Mazankowski Heart Institute, Edmonton, Canada
By September 2022, more than 600 million cases of SARS-CoV-2 infection have been reported globally, resulting in over 6.5 million deaths. COVID-19 mortality risk estimators are often, however, developed with small unrepresentative samples and with methodological limitations. It is highly important to develop predictive tools for pulmonary embolism (PE) in COVID-19 patients as one of the most severe preventable complications of COVID-19. Early recognition can help provide life-saving targeted anti-coagulation therapy right at admission. Using a dataset of more than 800,000 COVID-19 patients from an international cohort, we propose a cost-sensitive gradient-boosted machine learning model that predicts occurrence of PE and death at admission. Logistic regression, Cox proportional hazards models, and Shapley values were used to identify key predictors for PE and death. Our prediction model had a test AUROC of 75.9% and 74.2%, and sensitivities of 67.5% and 72.7% for PE and all-cause mortality respectively on a highly diverse and held-out test set. The PE prediction model was also evaluated on patients in UK and Spain separately with test results of 74.5% AUROC, 63.5% sensitivity and 78.9% AUROC, 95.7% sensitivity. Age, sex, region of admission, comorbidities (chronic cardiac and pulmonary disease, dementia, diabetes, hypertension, cancer, obesity, smoking), and symptoms (any, confusion, chest pain, fatigue, headache, fever, muscle or joint pain, shortness of breath) were the most important clinical predictors at admission. Age, overall presence of symptoms, shortness of breath, and hypertension were found to be key predictors for PE using our extreme gradient boosted model. This analysis based on the, until now, largest global dataset for this set of problems can inform hospital prioritisation policy and guide long term clinical research and decision-making for COVID-19 patients globally. Our machine learning model developed from an international cohort can serve to better regulate hospital risk prioritisation of at-risk patients. © The Author(s) 2024.
Adult; Aged; Aged, 80 and over; Cohort Studies; COVID-19; Female; Hospitalization; Humans; Machine Learning; Male; Middle Aged; Pulmonary Embolism; Risk Factors; SARS-CoV-2; Spain; United Kingdom; adult; aged; cohort analysis; complication; coronavirus disease 2019; epidemiology; female; hospitalization; human; isolation and purification; lung embolism; machine learning; male; middle aged; mortality; risk factor; Severe acute respiratory syndrome coronavirus 2; Spain; United Kingdom; very elderly
Institute for Clinical Research; Rhodes Scholarships; NIHR HPRU; Prince Charles Hospital Foundation; NIHR Health Protection Research Unit; Seventh Framework Programme, FP7; Instituto de Salud Carlos III, ISCIII; INSERM; Artificial Intelligence for Pandemics; European Centre for Disease Prevention and Control, ECDC; Groote Schuur Hospital Covid ICU; National Institutes of Health, NIH; South Eastern Norway Health Authority and the Research Council of Norway; Wellcome Trust, WT; COVID-19 Clinical M
Funding text 1: This work was made possible by the UK Foreign, Commonwealth and Development Office and Wellcome [215091/Z/18/Z, 222410/Z/21/Z, 225288/Z/22/Z and 220757/Z/20/Z]; the Bill & Melinda Gates Foundation [OPP1209135]; the philanthropic support of the donors to the University of Oxford\u2019s COVID-19 Research Response Fund (0009109); CIHR Coronavirus Rapid Research Funding Opportunity OV2
Nature Research
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