Publikasi Scopus 2024 per tanggal 31 Juli 2024 (607 artikel)

Hidayati E.L.; Fahlevi R.; Puspitasari H.A.; Tartila; Puspaningtyas N.W.; Primacakti F.; Saraswati M.; Miranda M.E.; Prawira Y.; Prayitno A.; Pardede S.O.; Putri N.D.
Hidayati, Eka Laksmi (57200542624); Fahlevi, Reza (57220071298); Puspitasari, Henny Adriani (57214119502); Tartila (58627205500); Puspaningtyas, Niken Wahyu (57223288515); Primacakti, Fitri (57208602430); Saraswati, Meilania (57208472364); Miranda, Monik Ediana (57221601685); Prawira, Yogi (55455747000); Prayitno, Ari (57193342301); Pardede, Sudung Oloan (57210394278); Putri, Nina Dwi (57200573842)
57200542624; 57220071298; 57214119502; 58627205500; 57223288515; 57208602430; 57208472364; 57221601685; 55455747000; 57193342301; 57210394278; 57200573842
Emerging progressive atypical acute kidney injury in young children linked to ethylene glycol and diethylene glycol intoxication
2024
Pediatric Nephrology
39
3
897
904
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0
Department of Child Health, Faculty of Medicine Universitas Indonesia, Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Department of Pathological Anatomy, Faculty of Medicine Universitas Indonesia, Cipto Mangunkusumo Hospital, Jakarta, Indonesia
Hidayati E.L., Department of Child Health, Faculty of Medicine Universitas Indonesia, Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Fahlevi R., Department of Child Health, Faculty of Medicine Universitas Indonesia, Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Puspitasari H.A., Department of Child Health, Faculty of Medicine Universitas Indonesia, Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Tartila, Department of Child Health, Faculty of Medicine Universitas Indonesia, Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Puspaningtyas N.W., Department of Child Health, Faculty of Medicine Universitas Indonesia, Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Primacakti F., Department of Child Health, Faculty of Medicine Universitas Indonesia, Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Saraswati M., Department of Pathological Anatomy, Faculty of Medicine Universitas Indonesia, Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Miranda M.E., Department of Pathological Anatomy, Faculty of Medicine Universitas Indonesia, Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Prawira Y., Department of Child Health, Faculty of Medicine Universitas Indonesia, Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Prayitno A., Department of Child Health, Faculty of Medicine Universitas Indonesia, Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Pardede S.O., Department of Child Health, Faculty of Medicine Universitas Indonesia, Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Putri N.D., Department of Child Health, Faculty of Medicine Universitas Indonesia, Cipto Mangunkusumo Hospital, Jakarta, Indonesia
Background: There had been a sudden surge of unusually severe and rapidly progressing acute kidney injury (AKI) incidence in Indonesia since August 2022 which did not correspond to the rise of COVID-19 incidence. We suspected this was related to ethylene glycol (EG) and diethylene glycol (DEG) intoxication. This study is aimed at describing the clinical and laboratory characteristics of AKI related to D(EG) intoxication in order to spread awareness of the possibility of intoxication in cases of rapidly progressing AKI with unknown etiology. Methods: We conducted a cross-sectional study by collecting secondary data from the pediatric AKI registry at a national referral hospital in Jakarta, Indonesia. Data on children admitted from January to November 2022 with diagnosis of stage 3 AKI based on KDIGO criteria were included. Data regarding demographics, symptoms prior to anuria, laboratory results, infection panel including COVID-19 status, treatment administered, and mortality were analyzed. Results: Sixteen patients tested positive for EG and DEG, all with history of consuming syrup-based medications. High anion gap metabolic acidosis was observed in majority of patients with mean pH 7.33 ± 0.07 and mean anion gap 15.6 ± 7.8 mEq/L. No patient had high osmolal gap (mean osmolal gap 3.46 ± 4.68). One deceased patient, who had kidney biopsy performed, showed severe damage and calcium oxalate crystals in the kidney tissue. Mortality was recorded in six patients (37.5%). Conclusion: Careful history taking of patient’s clinical course, including consumption of syrup-based medications and laboratory findings, might aid clinicians to establish a working diagnosis of D(EG) intoxication without needing to wait for blood toxicology test. Early diagnosis and therapy are crucial to prevent substantial mortality. Graphical abstract: [Figure not available: see fulltext.] © 2023, The Author(s), under exclusive licence to International Pediatric Nephrology Association.
Acute kidney injury; Diethylene glycol; Ethylene glycol; Pediatric
Acidosis; Acute Kidney Injury; Child; Child, Preschool; COVID-19; Cross-Sectional Studies; Ethylene Glycol; Ethylene Glycols; Humans; calcium oxalate; diethylene glycol; ethylene glycol; diethylene glycol; ethylene glycol; ethylene glycol derivative; acute kidney failure; anuria; Article; awareness; child; child health; clinical article; coronavirus disease 2019; cross-sectional study; demography; disease association; disease severity; female; human; human tissue; Indonesia; intoxication; kidney biopsy; male; metabolic acidosis; mortality; pH measurement; syrup; trend study; acidosis; acute kidney failure; coronavirus disease 2019; preschool child
Fahreza Aditya Neldy; Indonesian Pediatric Society; Ministry of Health of the Republic of Indonesia
We dedicated this work to the children and family who were affected by EG/DEG intoxication. Our greatest gratitude to all help from the Minister of Health Republic of Indonesia: Budi Gunadi Sadikin and his staff: Rizka Andalusia, The Indonesian Pediatric Society, the expert in Gambia and Melbourne: Prof Stephen Allen, Prof Vivian, Prof Julie Bines, Prof Trevor Duke, our hospital management: Fatima
Springer Science and Business Media Deutschland GmbH
0931041X
37755463
Article
Q1
768
6321