Riset dan Pengabdian Masyarakat
Do Research Sosial Service and Innovation
Publikasi Scopus 2024 per tanggal 31 Juli 2024 (607 artikel)
Publikasi Scopus 2024 per tanggal 31 Juli 2024 (607 artikel)
Sukor, Norlela (23969589600); Sunthornyothin, Sarat (6507106810); Tran, Thang V (57452764800); Tarigan, Tri Juli (36057746500); Mercado-Asis, Leilani B (6602441282); Sum, Satha (59177614300); Aung, Moe Wint (57225889658); Yong, Alice M. L (36520258200); Tedjo, Tania (59177459000); Villa, Michael (56265865600); Khaing, Nang Ei Ei (56358841100); Azizan, Elena Aisha (26538651700); Kang, Waye Hann (57210785835); Lim, Vivien (55340585600); Teo, Ada E. D (56004524300); Zhang, Meifen (57217073677); Tra
Health Care Challenges in the Management of Primary Aldosteronism in Southeast Asia
2024
Journal of Clinical Endocrinology and Metabolism
109
7
1718
1725
7
0
https://www.scopus.com/inward/record.uri?eid=2-s2.0-85196323366&doi=10.1210%2fclinem%2fdgae039&partnerID=40&md5=b67fdbbb013fa2d8838b2f25e8d0e84a
Department of Medicine, Faculty of Medicine, Universiti Kebangsaan Malaysia, Kuala Lumpur, 50300, Malaysia; Department of Medicine, Hospital Canselor Tuanku Muhriz, Kuala Lumpur, 56000, Malaysia; Department of Medicine, Faculty of Medicine, Chulalongkorn University, Bangkok, 10330, Thailand; Department of Endocrinology, University of Medicine and Pharmacy at Ho Chi Minh City, Ho Chi Minh City, 700000, Viet Nam; Division of Endocrinology, Department of Internal Medicine, Faculty of Medicine, University of Indonesia, Cipto Mangunkusumo Hospital, Jakarta, 10430, Indonesia; Faculty of Medicine and Surgery, University of Santo Tomas, Manila, 1008, Philippines; Department of Internal Medicine, Calmette Hospital, Phnom Penh, 12201, Cambodia; Department of Endocrinology, University of Medicine 1, Yangon General Hospital, Yangon, 11131, Myanmar; Department of Internal Medicine, R.I.P.A.S. Hospital, Bandar Seri Begawan BA1712, Brunei Darussalam; Department of Internal Medicine, Faculty of Medicine, Universitas Diponegoro, Jawa Tengah, Semarang, 50275, Indonesia; Philippines Center for Diabetes, Thyroid and Endocrine Disorders, St. Luke's Medical Center, Taguig, 1634, Philippines; Health Services Research, Changi General Hospital, Singapore, 529889, Singapore; Department of Medicine, Faculty of Medicine and Health Sciences, University Tunku Abdul Rahman, Kuala Lumpur, 53300, Malaysia; Gleneagles Medical Centre, Singapore, 258500, Singapore; Department of Medicine, Division of Endocrinology, National University Health System, Singapore, 119228, Singapore; Department of Endocrinology, Changi General Hospital, Singapore, 529889, Singapore; Duke National University of Singapore (NUS) Medical School, Singapore, 169857, Singapore
Context: While guidelines have been formulated for the management of primary aldosteronism (PA), following these recommendations may be challenging in developing countries with limited health care access. Objective: We aimed to assess the availability and affordability of health care resources for managing PA in the Association of Southeast Asian Nations (ASEAN) region, which includes low-middle-income countries. Methods: We instituted a questionnaire-based survey to specialists managing PA, assessing the availability and affordability of investigations and treatment. Population and income status data were taken from the national census and registries. Results: Nine ASEAN country members (48 respondents) participated. While screening with aldosterone-renin ratio is performed in all countries, confirmatory testing is routinely performed in only 6 countries due to lack of facilities and local assays, and cost constraint. Assays are locally available in only 4 countries, and some centers have a test turnaround time exceeding 3 weeks. In 7 countries (combined population of 442 million), adrenal vein sampling (AVS) is not routinely performed due to insufficient radiological facilities or trained personnel, and cost constraint. Most patients have access to adrenalectomy and medications. In 6 countries, the cost of AVS and adrenalectomy combined is more than 30% of its annual gross domestic product per capita. While most patients had access to spironolactone, it was not universally affordable. Conclusion: Large populations currently do not have access to the health care resources required for the optimal management of PA. Greater efforts are required to improve health care access and affordability. Future guideline revisions for PA may need to consider these limitations. © 2024 The Author(s). Published by Oxford University Press on behalf of the Endocrine Society.
Adrenalectomy; Asia, Southeastern; Delivery of Health Care; Developing Countries; Disease Management; Health Services Accessibility; Humans; Hyperaldosteronism; Surveys and Questionnaires; aldosterone; captopril; metadrenalin; renin; spironolactone; warfarin; adrenal incidentaloma; adrenalectomy; adult; Article; computer assisted tomography; cost effectiveness analysis; drug cost; female; fluoroscopy; gross national product; health care access; human; hyperaldosteronism; hypertension; hypokalemia; Japan; male; middle aged; practice guideline; prevalence; primary hyperaldosteronism; quality of life; questionnaire; retrospective study; South Africa; Southeast Asia; blood; developing country; diagnosis; disease management; epidemiology; health care delivery; Southeast Asia; therapy
National University of Singapore, NUS; National Medical Research Council, NMRC
Funding text 1: This work was supported by a Global Health Support Award [03/FY2023/P1/17-A32] by SingHealth Duke\u2013NUS Medical School. ; Funding text 2: T.H.P. is supported by the NMRC Transition Award, Singapore. The other authors have nothing to disclose.
Endocrine Society
0021972X
38261997
Article
Q1
1776
1607