Publikasi Scopus FKUI 2021 per tanggal 31 Juli 2021 (507 artikel)

Giantini A., Timan I.S., Listiyaningsih E., Dharma R., Setiabudy R., Alwi I., Partakusuma L.G., Indrasari N.D., Harahap· A.R., Suparmin· S., Sahar W., Sukmawan R.
12776781400;6602793366;57224237184;12777817700;6602316235;15055173800;57224924047;6506289872;57224930255;57224935655;57224929934;8651025300;
Comparison of Light Transmission Aggregometry and VerifyNow in Detecting Clopidogrel Resistance and Factors Affecting Clopidogrel Resistance in AMI-EST Patients Undergoing Percutaneous Coronary Intervention: A Cross-Sectional Study
2021
Indonesian Biomedical Journal
13
2
163
169
Faculty of Medicine, Universitas Indonesia, Jl. Salemba Raya No.6, Jakarta, Indonesia; Department of Clinical Pathology, Cipto Mangunkusumo National Central General Hospital, Jl. Pangeran Diponegoro No.71, Jakarta, Indonesia; Harapan Kita Heart and Vascular Hospital, Jl. Letjen S. Parman Kav.87, Jakarta, Indonesia; Department of Internal Medicine, Cardiology Division, Metropolitan Medical Centre (MMC) Hospital, Jl. H.R. Rasuna Said Kav. C-21, Jakarta, Indonesia; Eijkman Institute, Jl. Pangeran Diponegoro No. 69, Jakarta, Indonesia
Giantini, A., Faculty of Medicine, Universitas Indonesia, Jl. Salemba Raya No.6, Jakarta, Indonesia, Department of Clinical Pathology, Cipto Mangunkusumo National Central General Hospital, Jl. Pangeran Diponegoro No.71, Jakarta, Indonesia; Timan, I.S., Faculty of Medicine, Universitas Indonesia, Jl. Salemba Raya No.6, Jakarta, Indonesia, Department of Clinical Pathology, Cipto Mangunkusumo National Central General Hospital, Jl. Pangeran Diponegoro No.71, Jakarta, Indonesia; Listiyaningsih, E., Harapan Kita Heart and Vascular Hospital, Jl. Letjen S. Parman Kav.87, Jakarta, Indonesia; Dharma, R., Faculty of Medicine, Universitas Indonesia, Jl. Salemba Raya No.6, Jakarta, Indonesia, Department of Clinical Pathology, Cipto Mangunkusumo National Central General Hospital, Jl. Pangeran Diponegoro No.71, Jakarta, Indonesia; Setiabudy, R., Faculty of Medicine, Universitas Indonesia, Jl. Salemba Raya No.6, Jakarta, Indonesia; Alwi, I., Department of Internal Medicine, Cardiology Division, Metropolitan Medical Centre (MMC) Hospital, Jl. H.R. Rasuna Said Kav. C-21, Jakarta, Indonesia; Partakusuma, L.G., Harapan Kita Heart and Vascular Hospital, Jl. Letjen S. Parman Kav.87, Jakarta, Indonesia; Indrasari, N.D., Faculty of Medicine, Universitas Indonesia, Jl. Salemba Raya No.6, Jakarta, Indonesia, Department of Clinical Pathology, Cipto Mangunkusumo National Central General Hospital, Jl. Pangeran Diponegoro No.71, Jakarta, Indonesia; Harahap·, A.R., Faculty of Medicine, Universitas Indonesia, Jl. Salemba Raya No.6, Jakarta, Indonesia, Eijkman Institute, Jl. Pangeran Diponegoro No. 69, Jakarta, Indonesia; Suparmin·, S., Faculty of Medicine, Universitas Indonesia, Jl. Salemba Raya No.6, Jakarta, Indonesia; Sahar, W., Harapan Kita Heart and Vascular Hospital, Jl. Letjen S. Parman Kav.87, Jakarta, Indonesia; Sukmawan, R., Harapan Kita Heart and Vascular Hospital, Jl. Letjen S. Parman Kav.87, Jakarta, Indonesia
BACKGROUND: Light transmission aggregometry (LTA) and VerifyNow is commonly used to measure platelet responsiveness to clopidogrel. This study aimed to compare the results of LTA and VerifyNow P2Y12 assay for assessing the clopidogrel resistance in patients undergoing percutaneous coronary intervention and determine factors affecting clopidogrel resistance. METHODS: The subjects were 119 patients who underwent percutaneous coronary intervention (PCI) and had given loading dose of 600 mg clopidogrel. Blood samples were taken at 6 hour after clopidogrel loading dose. Platelet aggregation was measured by LTA and Verify Now. RESULTS: LTA and VerifyNow assay showed fair agreement with Kappa=0.270, p=0.001. The proportion of resistance to clopidogrel using VerifyNow was 21.8% and LTA was 47.1%. Patients with diabetes melitus were more likely to develop clopidogrel resistance than patients without diabetes (OR of 7.67; 95% CI: 1.87-31.50; p=0.005). CONCLUSION: The ability of LTA and VerifyNow in detecting clopidogrel resistance were not comparable. Multivariate analysis results for VerifyNow shows diabetes mellitus as the greatest predictors of clopidogrel resistance. © 2021. All Rights Reserved.
agreement; clopidogrel resistance; LTA; predictor; VerifyNow
Prodia Education and Research Institute
20853297
Article
Q4
160
22228