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Publikasi Scopus 2024 per tanggal 30 Juni 2024 (499 artikel)
Publikasi Scopus 2024 per tanggal 30 Juni 2024 (499 artikel)
Simanjuntak, Rohayat B. (58976340400); Lie, Khie Chen (56606750200); Rumende, Cleopas M. (14325966300); Abdullah, Murdani (7103393434); Shatri, Hamzah (28767986500); Koesnoe, Soekamto (26028015000); Nainggolan, Leonard (23498394800); Rizka, Aulia (57203243658)
Validation of Drug Resistance in Pneumonia (DRIP) Score as Empirical Antibiotic Failure Predictor in Community-Acquired Pneumonia Patients in Cipto Mangunkusumo Hospital
2024
Acta Medica Indonesiana
56
1
55
62
7
0
https://www.scopus.com/inward/record.uri?eid=2-s2.0-85189801900&partnerID=40&md5=3115607e002981f88647564cad4325e9
Division of Respirology and Critical Care, Department of Internal Medicine, Faculty of Medicine, Universitas Indonesia-Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Division of Tropical Medicine and Infectious Disease, Department of Internal Medicine, Faculty of Medicine, Universitas Indonesia-Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Division of Gastroenterology, Department of Internal Medicine, Faculty of Medicine, Universitas Indonesia-Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Division of Psychosomatic, Department of Internal Medicine, Faculty of Medicine, Universitas Indonesia-Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Division of Allergy and Clinical Immunology, Department of Internal Medicine, Faculty of Medicine, Universitas Indonesia-Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Division of Geriatrics, Department of Internal Medicine, Faculty of Medicine, Universitas Indonesia-Cipto Mangunkusumo Hospital, Jakarta, Indonesia
Background: The incidence of CAP due to Drug-Resistant Pathogen (DRP) requires broad-spectrum antibiotic therapy, Drugs Resistance in Pneumonia (DRIP) score can predict these cases. The use of the DRIP score can prevent antibiotic failure and long hospitalization, but validation is needed so that the DRIP score can be used according to the local community at Cipto Mangunkusumo National Central Public Hospital. Methods: This research is a retrospective cohort study in CAP patients who were hospitalized during the period January 2019 to June 2020. Data were taken from medical records. Failure of empiric antibiotics occurs when one of these criteria is found: patient mortality, ICU transfer, and escalation of antibiotics as well as length of stay. Results: 480 patients met the criteria. There were 331 patients (69%) with a DRIP score of <4 and 149 patients (31%) with a DRIP score of≥4. A total of 283 patients (59%) of antibiotic failures were detailed in 174 patients with a DRIP score <4 and 109 patients DRIP score ≥4. DRIP calibration using the Hosmer-Lemeshow test obtained p-value= 0.667 (p>0.05). AUC observations on the ROC curve obtained 0.651 (95% CI; 0.601-0.700). Conclusion: The DRIP score has low accuracy performance and calibration value in predicting empirical antibiotic failure and poor discriminatory value. © 2024, Indonesian Society of Internal Medicine. All rights reserved.
Anti-Bacterial Agents; Community-Acquired Infections; Hospitalization; Hospitals; Humans; Pneumonia; Retrospective Studies; antiinfective agent; community acquired infection; hospital; hospitalization; human; pneumonia; retrospective study
Indonesian Society of Internal Medicine
01259326
38561875
Article
Q3
282
15714