Publikasi Scopus FKUI 2021 per tanggal 30 Juni 2021 (428 artikel)

Yani A., Dorothy D., Amaliah R.
57215433374;57224003330;57224001785;
Influence of Intestinal Strangulation Release on Ischemiareperfusion Injury in Sprague Dawley Rats
2021
Annals of African Surgery
18
2
90
95
1
Department of Surgery, Faculty of Medicine, Dr. Cipto Mangunkusumo General Hospital, Universitas Indonesia, Jakarta, Indonesia; Department of Surgery, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia
Yani, A., Department of Surgery, Faculty of Medicine, Dr. Cipto Mangunkusumo General Hospital, Universitas Indonesia, Jakarta, Indonesia; Dorothy, D., Department of Surgery, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Amaliah, R., Department of Surgery, Faculty of Medicine, Dr. Cipto Mangunkusumo General Hospital, Universitas Indonesia, Jakarta, Indonesia
Background: In intestinal ischemia, reperfusion towards the injured intestine can cause further injury to the intestine itself and to remote organs. This research aimed to evaluate the influence of intestinal strangulation release (SR) before resection on the intestine outside margin of the strangulated intestine compared with subjects without intestinal strangulation release (WSR). Methods: Fourteen male Sprague Dawley rats were subjected to strangulation of one loop of the distal ileum for 4 h. In the SR group, the strangulated intestine was released for 5 min and then resected for necrotic parts. In the WSR group, the strangulated intestine was immediately resected WSR. The control group received a sham laparotomy. Four hours after the second laparotomy, the animals were sacrificed, and intestinal samples were taken for histomorphological analysis and measurement of intestinal malondialdehyde (MDA) level. Results: The injury on the histomorphological intestinal mucosa and intestinal MDA level were insignificantly higher in the SR group than in the WSR group (p>0.05). Conclusion: Intestinal SR before resection causes more tissue injury and oxidative stress on the intestine outside the strangulation section, but the difference is not statistically significant. © 2021 Surgical Society of Kenya. All rights reserved.
Intestinal ischemia; Intestinal strangulation release; Intestine injury; Ischemia-reperfusion injury; Malondialdehyde
Surgical Society of Kenya
19999674
Article
Q3
193
18891

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