Publikasi Scopus FKUI 2021 per tanggal 30 Juni 2021 (428 artikel)

Simadibrata D.M., Calvin J., Wijaya A.D., Ibrahim N.A.A.
57202134322;57221411392;57221411463;57221410260;
Neutrophil-to-lymphocyte ratio on admission to predict the severity and mortality of COVID-19 patients: A meta-analysis
2021
American Journal of Emergency Medicine
42
60
69
3
Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia
Simadibrata, D.M., Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Calvin, J., Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Wijaya, A.D., Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Ibrahim, N.A.A., Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia
Background: The neutrophil-to-lymphocyte ratio (NLR), an inflammatory marker, was suggested to be predictive of severity and mortality in COVID-19 patients. Here, we investigated whether NLR levels on admission could predict the severity and mortality of COVID-19 patients. Methods: A literature search was conducted on 23 July 2020 to retrieve all published articles, including grey literature and preprints, investigating the association between on-admission NLR values and severity or mortality in COVID-19 patients. A meta-analysis was performed to determine the overall standardized mean difference (SMD) in NLR values and the pooled risk ratio (RR) for severity and mortality with the 95% Confidence Interval (95%CI). Results: A total of 38 articles, including 5699 patients with severity outcomes and 6033 patients with mortality outcomes, were included. The meta-analysis showed that severe and non-survivors of COVID-19 had higher on-admission NLR levels than non-severe and survivors (SMD 0.88; 95%CI 0.72–1.04; I2 = 75.52% and 1.87; 95%CI 1.25–2.49; I2 = 97.81%, respectively). Regardless of the different NLR cut-off values, the pooled mortality RR in patients with elevated vs. normal NLR levels was 2.74 (95%CI 0.98–7.66). Conclusion: High NLR levels on admission were associated with severe COVID-19 and mortality. Further studies need to focus on determining the optimal cut-off value for NLR before clinical use. © 2021 Elsevier Inc.
COVID-19; Meta-analysis; Mortality; Neutrophil-to-lymphocyte ratio; Severity
Article; coronavirus disease 2019; disease association; disease severity; hospital admission; human; meta analysis; mortality; mortality risk; neutrophil lymphocyte ratio; outcome assessment; prediction; priority journal; quality control; risk assessment; sensitivity and specificity; sex ratio; survivor; systematic review; blood; diagnosis; hospitalization; lymphocyte count; neutrophil; severity of illness index; survival rate; COVID-19; Hospitalization; Humans; Lymphocyte Count; Neutrophils; Severity of Illness Index; Survival Rate
W.B. Saunders
7356757
33453617
Article
Q1
659
7429

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