Publikasi Scopus FKUI 2021 per tanggal 30 Juni 2021 (428 artikel)

Riset dan Pengabdian Masyarakat Do Research Sosial Service and Innovation

Publikasi Scopus FKUI 2021 per tanggal 30 Juni 2021 (428 artikel)

153

Authors (Last_Name)

Pangjaya L.F., Khaerunnisa S., Mazfufah N.F., Budiman R.L., Antarianto R.D.

Author S Id

57222624829;57221948155;57215595521;57222627263;57190862806;

Title

Investigating different type of ovary cancer cell line for NK cell in vitro co-culture cytotoxic assay

Year

2021

Source Title

AIP Conference Proceedings

Volume

2344

Issue

Art No

40010

Page Start

Page End

Page Count

Cited By

Link

https://www.scopus.com/inward/record.uri?eid=2-s2.0-85103511346&doi=10.1063%2f5.0049155&partnerID=40&md5=34e5a053702d387eeb6890faa2868915

Affiliations

Biology Undergraduate Program, Faculty of Mathematics and Natural Science, Universitas Indonesia, Kampus UI Depok, West Java, 16424, Indonesia; Stem Cell and Tissue Engineering Research Cluster, Indonesian Medical Education and Research Institute (IMERI), Universitas Indonesia, Salemba Raya, Jakarta, West Java, 10430, Indonesia; Department of Biology, Faculty of Mathematics and Natural Science, Universitas Indonesia, Kampus UI Depok, West Java, 16424, Indonesia; Department of Histology, Faculty of Medicine, Universitas Indonesia, Salemba Raya, Jakarta, West Java, 10430, Indonesia

Authors With Affiliations

Pangjaya, L.F., Biology Undergraduate Program, Faculty of Mathematics and Natural Science, Universitas Indonesia, Kampus UI Depok, West Java, 16424, Indonesia, Stem Cell and Tissue Engineering Research Cluster, Indonesian Medical Education and Research Institute (IMERI), Universitas Indonesia, Salemba Raya, Jakarta, West Java, 10430, Indonesia; Khaerunnisa, S., Biology Undergraduate Program, Faculty of Mathematics and Natural Science, Universitas Indonesia, Kampus UI Depok, West Java, 16424, Indonesia, Stem Cell and Tissue Engineering Research Cluster, Indonesian Medical Education and Research Institute (IMERI), Universitas Indonesia, Salemba Raya, Jakarta, West Java, 10430, Indonesia; Mazfufah, N.F., Department of Biology, Faculty of Mathematics and Natural Science, Universitas Indonesia, Kampus UI Depok, West Java, 16424, Indonesia; Budiman, R.L., Department of Biology, Faculty of Mathematics and Natural Science, Universitas Indonesia, Kampus UI Depok, West Java, 16424, Indonesia; Antarianto, R.D., Stem Cell and Tissue Engineering Research Cluster, Indonesian Medical Education and Research Institute (IMERI), Universitas Indonesia, Salemba Raya, Jakarta, West Java, 10430, Indonesia, Department of Histology, Faculty of Medicine, Universitas Indonesia, Salemba Raya, Jakarta, West Java, 10430, Indonesia

Abstract

Ovarian cancer is one of the gynecologic cancers with a high mortality rate and increased incidence. Surgery and therapies are used to treat ovarian cancer patients. Therapies such as chemotherapy and radiotherapy can cause resistance therefore immunotherapy using natural killer (NK) cells can be an alternative therapy. NK cells have shown an important role in anticancer activity because it is able to kill target cells without prior sensitization and can acquire immunology memory. However, NK cells as immunotherapy have low capacity and efficacy on infiltrating ovarian cancer's tumor microenvironment. To overcome these NK cells need to be induced with certain antigen resulting in enhanced NK cells. Enhanced NK cells display a higher cytotoxic activity that can be seen by co-culturing enhanced NK cells with ovarian cancer cell lines. In this mini-review, the selection of ovarian cancer cell lines was displayed to offer reliable consideration to obtain the expected research endpoint. © 2021 Author(s).

Author Keywords

co-culture; cytotoxic assay; NK cells; ovarian cancer; ovarian cancer cell lines

Index Keywords

Publisher

American Institute of Physics Inc.

Issn

0094243X

Isbn

9,78074E+12

Pubmed Id

Document Type

Conference Paper

Sjr Best Quartile

Sjr

190

Sjr Rank

19092