Publikasi Scopus FKUI 2021 per tanggal 30 Juni 2021 (428 artikel)

Authors (Last_Name)

Uchihara Y., Permata T.B.M., Sato H., Shibata A.

Author S Id

57221723636;57197808751;55697961900;8323572900;

Title

Modulation of immune responses by DNA damage signaling

Year

2021

Source Title

DNA Repair

Volume

104

Issue

Art No

103135

Page Start

Page End

Page Count

Cited By

Link

https://www.scopus.com/inward/record.uri?eid=2-s2.0-85106368761&doi=10.1016%2fj.dnarep.2021.103135&partnerID=40&md5=6d7c9e9634795d347738b7c970442465

Affiliations

Signal Transduction Program, Gunma University Initiative for Advanced Research (GIAR), Gunma UniversityGunma, Japan; Department of Radiation Oncology, Faculty of Medicine Universitas Indonesia, Dr. Cipto Mangunkusumo Hospital, Jakarta, 10430, Indonesia; Department of Radiation Oncology, Gunma University, Gunma, Japan

Authors With Affiliations

Uchihara, Y., Signal Transduction Program, Gunma University Initiative for Advanced Research (GIAR), Gunma UniversityGunma, Japan; Permata, T.B.M., Department of Radiation Oncology, Faculty of Medicine Universitas Indonesia, Dr. Cipto Mangunkusumo Hospital, Jakarta, 10430, Indonesia; Sato, H., Department of Radiation Oncology, Gunma University, Gunma, Japan; Shibata, A., Signal Transduction Program, Gunma University Initiative for Advanced Research (GIAR), Gunma UniversityGunma, Japan

Abstract

An accumulation of evidence indicates the importance of DNA damage signaling in modulating immune responses. Indeed, understanding the mechanism that underlies signal transduction originating from DNA damage is vital to overcoming refractory cancer, particularly when cancer immune therapy is applied in combination with DNA damage-dependent radio/chemotherapy. In addition, immune-associated responses to such signals can aggravate the symptoms of infections, allergies, autoimmune disease, and aging. In this review, we discuss how cells transduce signals, triggered by DNA damage, from their origins to neighboring cells and how this affects immune and inflammatory responses. © 2021 Elsevier B.V.

Author Keywords

Cancer therapy; DNA damage signaling; Immune crosstalk; Immune-associated disease; Inflammation

Index Keywords

Publisher

Elsevier B.V.

Issn

15687864

Isbn

Pubmed Id

Document Type

Article

Sjr Best Quartile

Sjr

2036

Sjr Rank

1271