Publikasi Scopus FKUI 2021 per tanggal 30 Juni 2021 (428 artikel)

Hanifah N., Wiweko B., Bowolaksono A.
57200075370;43061741400;57205093224;
FSHR and LHR mRNA expression in granulosa cells of poor responder
2021
Journal of Physics: Conference Series
1725
1
12057
Department of Biology, Faculty of Mathematics and Natural Sciences (FMIPA), Universitas Indonesia, Depok, 16424, Indonesia; Department of Obstetric and Gynecology, Faculty of Medicine, Universitas Indonesia, Depok, 16424, Indonesia
Hanifah, N., Department of Biology, Faculty of Mathematics and Natural Sciences (FMIPA), Universitas Indonesia, Depok, 16424, Indonesia; Wiweko, B., Department of Obstetric and Gynecology, Faculty of Medicine, Universitas Indonesia, Depok, 16424, Indonesia; Bowolaksono, A., Department of Biology, Faculty of Mathematics and Natural Sciences (FMIPA), Universitas Indonesia, Depok, 16424, Indonesia
In Vitro Fertilization (IVF) is one of the most commonly used procedures to help pregnancies in couples who have infertility problems. One of the problems of infertility is poor ovarian response and the woman who experiences it is known as poor responder. Poor responders do not have an adequate ovarian response to gonadotropin in ovarian stimulation. The success of fertilization in poor responders tends to be low due to low quantity and is generally followed by low oocyte quality. Gonadotropins consisting of FSH and LH, play a role in follicle development and ovulation. The follicle response in capturing gonadotropins depends on the exact bond between the hormone and its receptor (FSHR and LHR) in the granulosa cells surrounding the oocyte. The purpose of this research is to know the expression level of fshr and lhr mRNA in granulosa cells of poor responders through real-time PCR method which then tested statistically using t-test. Fourteen samples of each poor responders and normal women were used in this research. The results showed insignificant differences between expression level of fshr and lhr mRNA in granulosa cells of poor responders and normal women (p > 0.05). © 2021 Journal of Physics: Conference Series.
FSHR; LHR; Poor ovarian response; Real-time PCR
Cytology; Polymerase chain reaction; Expression levels; Follicle development; Granulosa cells; In-vitro; mRNA expression; Real-time PCR method; T-tests; Cells
IOP Publishing Ltd
17426588
Conference Paper
Q3
227
17171