Department of Pharmacology and Therapeutics Faculty of Medicine Universitas Indonesia, Indonesia; Clinical Pharmacology Specialist Program, Faculty of Medicine Universitas Indonesia, Jakarta, Indonesia; Department of Pharmacy, Sanata Dharma University, Jogyakarta, Indonesia; Infection Disease Hospital, Prof. Dr Sulianti Saroso, Jakarta, Indonesia
Arozal, W., Department of Pharmacology and Therapeutics Faculty of Medicine Universitas Indonesia, Indonesia; Diliana, D., Clinical Pharmacology Specialist Program, Faculty of Medicine Universitas Indonesia, Jakarta, Indonesia; Wikanendra, G.B., Department of Pharmacy, Sanata Dharma University, Jogyakarta, Indonesia; Purwantyastuti, P., Department of Pharmacology and Therapeutics Faculty of Medicine Universitas Indonesia, Indonesia; Rusli, A., Infection Disease Hospital, Prof. Dr Sulianti Saroso, Jakarta, Indonesia
Objective: To analyse factors affecting the recurrence of TB in a tertiary hospital in Jakarta, Indonesia. Methods: This is a hospital-based survey, located in Jakarta, in the period of January 2014-December 2018. All patients with recurrent TB were included in the study, while the samples with successful treatment in the same period were chosen by consecutive sampling. Statistical analysis of clinical characteristics of both study groups was conducted. Results: The medical records of 2322 TB patients who presented to Sulianti Saroso Hospital were analysed retrospectively. Ninety-four cases of recurrent TB that met inclusion and exclusion criteria were included in the study. It was observed that factors affecting recurrence of TB were medication compliance (p = .007, odds ratio (OR) 0.38 [CI 95% 0.19-0.76]) and appearance of lung cavity lesions in the first thorax x-ray examination (p < .001, OR 0.08 [CI 95% 0.03-0.20]). Conclusion: There was a relationship between recurrent TB and medication compliance and the appearance of lung cavity lesions in the first thorax x-ray examination. ? 2021 Pakistan Medical Association. All rights reserved.