Publikasi Scopus 2024 per tanggal 30 September 2024 (820 artikel)

Putera I.; Schrijver B.; Kolijn P.M.; van Stigt A.C.; ten Berge J.C.E.M.; IJspeert H.; Nagtzaam N.M.A.; Swagemakers S.M.A.; van Laar J.A.M.; Agrawal R.; Rombach S.M.; van Hagen P.M.; La Distia Nora R.; Dik W.A.
Putera, Ikhwanuliman (56485949000); Schrijver, Benjamin (36345029700); Kolijn, P. Martijn (57217168818); van Stigt, Astrid C. (57221257282); ten Berge, Josianne C. E. M. (56601233400); IJspeert, Hanna (26321094900); Nagtzaam, Nicole M. A. (24537498500); Swagemakers, Sigrid M. A. (6506322464); van Laar, Jan A. M. (7006252355); Agrawal, Rupesh (7201475180); Rombach, Saskia M. (58860662800); van Hagen, P. Martin (57210765646); La Distia Nora, Rina (56001881000); Dik, Willem A. (6603280038)
56485949000; 36345029700; 57217168818; 57221257282; 56601233400; 26321094900; 24537498500; 6506322464; 7006252355; 7201475180; 58860662800; 57210765646; 56001881000; 6603280038
A serum B-lymphocyte activation signature is a key distinguishing feature of the immune response in sarcoidosis compared to tuberculosis
2024
Communications Biology
7
1
1114
0
Department of Ophthalmology, Erasmus University Medical Center, Rotterdam, Netherlands; Department of Internal Medicine Section Allergy & amp; Clinical Immunology, Erasmus University Medical Center, Rotterdam, Netherlands; Laboratory Medical Immunology, Department of Immunology, Erasmus University Medical Center, Rotterdam, Netherlands; Department of Ophthalmology, Faculty of Medicine, Universitas Indonesia, Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Academic Center for Rare Immunological Diseases (Rare Immunological Disease Center), Erasmus University Medical Center, Rotterdam, Netherlands; Department of Bioinformatics, Erasmus MC University Medical Center Rotterdam, Rotterdam, Netherlands; National Healthcare Group Eye Institute, Tan Tock Seng Hospital, Singapore, Singapore; Lee Kong Chian School of Medicine, Nanyang Technological University, Singapore, Singapore; Ophthalmology and Visual Sciences Academic Clinical Program, Duke NUS University, Singapore, Singapore; Singapore Eye Research Institute, Singapore, Singapore; Moorfields Eye Hospital, London, United Kingdom
Putera I., Department of Ophthalmology, Erasmus University Medical Center, Rotterdam, Netherlands, Department of Internal Medicine Section Allergy & amp; Clinical Immunology, Erasmus University Medical Center, Rotterdam, Netherlands, Laboratory Medical Immunology, Department of Immunology, Erasmus University Medical Center, Rotterdam, Netherlands, Department of Ophthalmology, Faculty of Medicine, Universitas Indonesia, Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Schrijver B., Laboratory Medical Immunology, Department of Immunology, Erasmus University Medical Center, Rotterdam, Netherlands; Kolijn P.M., Laboratory Medical Immunology, Department of Immunology, Erasmus University Medical Center, Rotterdam, Netherlands; van Stigt A.C., Department of Internal Medicine Section Allergy & amp; Clinical Immunology, Erasmus University Medical Center, Rotterdam, Netherlands, Laboratory Medical Immunology, Department of Immunology, Erasmus University Medical Center, Rotterdam, Netherlands, Academic Center for Rare Immunological Diseases (Rare Immunological Disease Center), Erasmus University Medical Center, Rotterdam, Netherlands; ten Berge J.C.E.M., Department of Ophthalmology, Erasmus University Medical Center, Rotterdam, Netherlands; IJspeert H., Laboratory Medical Immunology, Department of Immunology, Erasmus University Medical Center, Rotterdam, Netherlands, Academic Center for Rare Immunological Diseases (Rare Immunological Disease Center), Erasmus University Medical Center, Rotterdam, Netherlands; Nagtzaam N.M.A., Laboratory Medical Immunology, Department of Immunology, Erasmus University Medical Center, Rotterdam, Netherlands; Swagemakers S.M.A., Department of Bioinformatics, Erasmus MC University Medical Center Rotterdam, Rotterdam, Netherlands; van Laar J.A.M., Department of Internal Medicine Section Allergy & amp; Clinical Immunology, Erasmus University Medical Center, Rotterdam, Netherlands; Agrawal R., National Healthcare Group Eye Institute, Tan Tock Seng Hospital, Singapore, Singapore, Lee Kong Chian School of Medicine, Nanyang Technological University, Singapore, Singapore, Ophthalmology and Visual Sciences Academic Clinical Program, Duke NUS University, Singapore, Singapore, Singapore Eye Research Institute, Singapore, Singapore, Moorfields Eye Hospital, London, United Kingdom; Rombach S.M., Department of Internal Medicine Section Allergy & amp; Clinical Immunology, Erasmus University Medical Center, Rotterdam, Netherlands; van Hagen P.M., Department of Internal Medicine Section Allergy & amp; Clinical Immunology, Erasmus University Medical Center, Rotterdam, Netherlands, Laboratory Medical Immunology, Department of Immunology, Erasmus University Medical Center, Rotterdam, Netherlands; La Distia Nora R., Department of Ophthalmology, Faculty of Medicine, Universitas Indonesia, Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Dik W.A., Laboratory Medical Immunology, Department of Immunology, Erasmus University Medical Center, Rotterdam, Netherlands
Sarcoidosis and tuberculosis (TB) are two granulomatous diseases that often share overlapping clinical features, including uveitis. We measured 368 inflammation-related proteins in serum in both diseases, with and without uveitis from two distinct geographically separated cohorts: sarcoidosis from the Netherlands and TB from Indonesia. A total of 192 and 102 differentially expressed proteins were found in sarcoidosis and active pulmonary TB compared to their geographical healthy controls, respectively. While substantial overlap exists in the immune-related pathways involved in both diseases, activation of B cell activating factor (BAFF) signaling and proliferation-inducing ligand (APRIL) mediated signaling pathways was specifically associated with sarcoidosis. We identified a B-lymphocyte activation signature consisting of BAFF, TNFRSF13B/TACI, TRAF2, IKBKG, MAPK9, NFATC1, and DAPP1 that was associated with sarcoidosis, regardless of the presence of uveitis. In summary, a difference in B-lymphocyte activation is a key discriminative immunological feature between sarcoidosis/ocular sarcoidosis (OS) and TB/ocular TB (OTB). © The Author(s) 2024.
Adult; B-Cell Activating Factor; B-Lymphocytes; Biomarkers; Female; Humans; Indonesia; Lymphocyte Activation; Male; Middle Aged; Netherlands; Sarcoidosis; Tuberculosis; Tuberculosis, Pulmonary; Uveitis; B cell activating factor; biological marker; adult; B lymphocyte; blood; comparative study; diagnosis; epidemiology; female; human; immunology; Indonesia; lung tuberculosis; lymphocyte activation; male; middle aged; Netherlands; sarcoidosis; tuberculosis; uveitis
Nature Research
23993642
39256610
Article
Q1
2090
1269