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Publikasi Scopus 2024 per tanggal 30 September 2024 (820 artikel)
Publikasi Scopus 2024 per tanggal 30 September 2024 (820 artikel)
Legiawati, Lili (57202804484); Suseno, Lis Surachmiati (57202804092); Sitohang, Irma Bernadette S. (56734569200); Yusharyahya, Shannaz Nadia (57211780941); Fahira, Alessa (57212585403); Ramadan, Edwin Ti (59262943400); Paramastri, Kanya (57220065022)
Adipose-derived stem cell conditioned medium for hair regeneration therapy in alopecia: a review of literature
2024
Archives of Dermatological Research
316
8
525
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https://www.scopus.com/inward/record.uri?eid=2-s2.0-85201364541&doi=10.1007%2fs00403-024-03255-y&partnerID=40&md5=df8bd5576e605c481a311e7c7a06e9fa
Department of Dermatology and Venereology, Faculty of Medicine, Universitas Indonesia Dr. Cipto Mangunkusumo National General Hospital Jakarta, Diponegoro no. 71 Kenari, Jakarta, Senen, 10430, Indonesia
To date, therapeutic choices for alopecia have shown limited effectiveness and safety, making the discovery of new therapeutic choices challenging. Adipose-derived stem cells conditioned-medium (ADSC-CM) contain various growth factors released by ADSCs that may support hair regrowth. This literature review aims to discover the effect and clinical impact of ADSC-CM in the treatment of alopecia. A comprehensive literature search was performed through four databases (Pubmed, ScienceDirect, Cochrane, and Scopus) in September 2021. A combination of search terms including “adipose-derived stem cells” and “alopecia” was used. Studies published in English that included ADSC-CM interventions on alopecia of all types were selected and summarized. A total of five studies were selected for review, all of which were case series. All studies showed a positive outcome for intervention. Outcomes measured in the studies include hair count or hair density, hair thickness, anagen, and telogen hair count. No adverse effects were reported from all studies. Limitations lie in the differences in intervention method, application, and length of treatment. ADSC-CM hair regeneration therapy is an effective and safe treatment for alopecia that may be combined with other types of therapy to improve outcomes. © The Author(s), under exclusive licence to Springer-Verlag GmbH Germany, part of Springer Nature 2024.
Adipose Tissue; Alopecia; Culture Media, Conditioned; Hair; Hair Follicle; Humans; Regeneration; Treatment Outcome; platelet derived growth factor; scatter factor; somatomedin; vasculotropin; adipose derived stem cell; alopecia; alopecia areata; case study; clinical effectiveness; cutaneous parameters; data base; hair count; hair density; hair growth; hair loss; hair regeneration; hair thickness; human; male type alopecia; outcome assessment; patient safety; Review; side effect; telogen hair count; therapy effect; tissue regeneration; treatment duration; treatment indication; adipose tissue; conditioned medium; cytology; drug effect; growth, development and aging; hair; hair follicle; regeneration; therapy; treatment outcome
Cipto Mangunkusumo Central Hospital; Fakultas Kedokteran, Universitas Indonesia, FKUI; National Research and Innovation Agency Badan Riset dan Inovasi Nasional; Badan Riset dan Inovasi Nasional, BRIN, (2987/E4/AK.04/2021)
Funding text 1: The authors would like to thank the Stem Cell Medical Technology Integrated Service Unit, Cipto Mangunkusumo Central Hospital, Faculty of Medicine, Universitas Indonesia for their support in this study.; Funding text 2: The authors would like to thank the National Research and Innovation Agency Badan Riset dan Inovasi Nasional (BRIN) for funding this research through Pendanaan Prio
Springer Nature
3403696
39153118
Review