Publikasi Scopus 2024 per tanggal 30 September 2024 (820 artikel)

Ladeska V.; Elya B.; Hanafi M.; Kusmardi; Rohmat S.S.
Ladeska, Vera (57211585163); Elya, Berna (14014224500); Hanafi, Muhammad (26644895300); Kusmardi (56966625300); Rohmat, Siti Saudah (59252402300)
57211585163; 14014224500; 26644895300; 56966625300; 59252402300
Pharmacognostic Evaluation and Antioxidant Activities of Tetracera indica (Christm. and Panz.) Merr
2024
HAYATI Journal of Biosciences
31
5
836
853
17
0
Department of Pharmacognosy and Phytochemistry, Faculty of Pharmacy, University of Indonesia, Depok, 16424, Indonesia; Department of Pharmacognosy and Phytochemistry, Faculty of Pharmacy and Science, University Muhammadiyah Prof. Dr. Hamka, Jakarta, 13460, Indonesia; Research Center for Chemistry, Indonesian National Research and Innovation Institute, Serpong, Indonesia; Department of Pharmacognosy and Phytochemistry, Faculty of Pharmacy, University of Pancasila, Jakarta, 12630, Indonesia; Department of Anatomic Pathology, Faculty of Medicine, University of Indonesia, Jakarta, 10340, Indonesia; Drug Development Research Cluster, Indonesia Medical Educational and Research Institute, Jakarta, 10340, Indonesia; Human Cancer Research Cluster, Indonesia Medical Educational and Research Institute, Jakarta, 10340, Indonesia
Ladeska V., Department of Pharmacognosy and Phytochemistry, Faculty of Pharmacy, University of Indonesia, Depok, 16424, Indonesia, Department of Pharmacognosy and Phytochemistry, Faculty of Pharmacy and Science, University Muhammadiyah Prof. Dr. Hamka, Jakarta, 13460, Indonesia; Elya B., Department of Pharmacognosy and Phytochemistry, Faculty of Pharmacy, University of Indonesia, Depok, 16424, Indonesia; Hanafi M., Research Center for Chemistry, Indonesian National Research and Innovation Institute, Serpong, Indonesia, Department of Pharmacognosy and Phytochemistry, Faculty of Pharmacy, University of Pancasila, Jakarta, 12630, Indonesia; Kusmardi, Department of Anatomic Pathology, Faculty of Medicine, University of Indonesia, Jakarta, 10340, Indonesia, Drug Development Research Cluster, Indonesia Medical Educational and Research Institute, Jakarta, 10340, Indonesia, Human Cancer Research Cluster, Indonesia Medical Educational and Research Institute, Jakarta, 10340, Indonesia; Rohmat S.S., Department of Pharmacognosy and Phytochemistry, Faculty of Pharmacy and Science, University Muhammadiyah Prof. Dr. Hamka, Jakarta, 13460, Indonesia
The community uses Tetracera indica (Christm. and Panz.) Merr extensively as a traditional medicine. This plant was the main source of raw materials for herbal medicinal products, so identification was needed to ensure its authenticity through pharmacognosy evaluation. The present study evaluated macros-and microscopic characteristics, performed phytochemical analysis, and performed total phenolic (TPC) and flavonoid content (TFC) analysis. The organoleptic and macroscopic studies were carried out through sensory organs. The microscopic characteristics of leaf powder and twigs identification using chloral hydrate and distilled water. Numerous chemical reagents, TLC methods and LC-MS/MS analysis were employed in the phytochemical study. Research employed DPPH and FRAP tests to assess the antioxidant activity. Furthermore, quercetin was used as a marker of antioxidant activity. The morphological marker of the leaf T. indica showed the surface of the leaves is rough bristles, shape elliptic-oblong, margin serratus and phyllotaxy alternate. The stem is lignosus, and the rough stem surface is slightly peeling. The lower leaf surface had paracytic stomata and uniseriate trichomes with tapering ends. Raphide crystals and cork cells were detected in the powder analysis of the twigs. The ethyl acetate extract's twig had the highest TPC and TFC values. Ethyl acetate extract from Tetracera indica twigs has potent antioxidant activity with IC50 = 99.84±0.011 µg/ml (DPPH) and 4296.67±0.024 mol/g (FRAP). The study showed that Tetracera indica contains possible active components that could be developed as novel antioxidants. The result of this study might provide early verification and identification to obtain quality medicinal raw materials. © 2024, Bogor Agricultural University. All rights reserved.
Antioxidants; Macro-microscopic; Phytochemical; Tetracera indica
Badan Riset dan Inovasi Nasional, BRIN; National Research and Innovation Institute; Institut Pertanian Bogor, IPB; Ministry of Research, Technology and Higher Education, The Government of Indonesia Republic for Research Foundation, (NKB-885/UN2.RST/ HKP.05.00/2022)
The authors express their sincere gratitude toThe Ministry of Research, Technology and Higher Education, The Government of Indonesia Republic for Research Foundation via Doctoral Dissertation Research Grant (PDD) No. NKB-885/UN2.RST/ HKP.05.00/2022. The authors are grateful to the Center for Study of Tropical Biopharmaca of LPPM at Bogor Agricultural University in West Java for providing test samp
Bogor Agricultural University
19783019
Article
Q3
215
19165