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Publikasi Scopus 2024 per tanggal 30 September 2024 (820 artikel)
Publikasi Scopus 2024 per tanggal 30 September 2024 (820 artikel)
Mesiano, Taufik (57204830976); Rasyid, Al (56703146700); Gayatri, Anggi (57204275086); Kusumaningsih, Widjajalaksmi (56267405900); Witjaksono, Fiastuti (57070455800); Herqutanto (57192913567); Amalia, Lisda (57217252555); Andarwulan, Nuri (6507507623); Harris, Salim (55325116600)
Exploring the potential benefits of anthocyanins for individuals with cerebral small vessel disease
2024
Egyptian Journal of Neurology, Psychiatry and Neurosurgery
60
1
87
0
https://www.scopus.com/inward/record.uri?eid=2-s2.0-85198035864&doi=10.1186%2fs41983-024-00862-4&partnerID=40&md5=7eb1046e63ea79d5b3c7ba061d7b7f60
Doctoral Program in Medical Science Faculty of Medicine, Universitas Indonesia, Dr. Cipto Mangunkusumo Hospital, Jakarta, 10430, Indonesia; Department of Neurology, Faculty of Medicine, Universitas Indonesia, Dr. Cipto Mangunkusumo Hospital, Jakarta, 10430, Indonesia; Department of Pharmacology and Therapeutic, Faculty of Medicine, Universitas Indonesia, Dr. Cipto Mangunkusumo Hospital, Jakarta, 10430, Indonesia; Department of Medical Rehabilitation, Faculty of Medicine, Universitas Indonesia, Dr. Cipto Mangunkusumo Hospital, Jakarta, 10430, Indonesia; Department of Nutrition, Faculty of Medicine, Universitas Indonesia, Dr. Cipto Mangunkusumo Hospital, Jakarta, 10430, Indonesia; Department of Community Medicine, Faculty of Medicine, Universitas Indonesia, Jakarta, 10430, Indonesia; Department of Neurology, Faculty of Medicine, Universitas Padjadjaran, Bandung, 45363, Indonesia; Department of Food Science and Technology, IPB University, Bogor, 16680, Indonesia
Several studies have demonstrated the antioxidant and anti-inflammatory properties of anthocyanins, as well as their potential phytoestrogenic activity, which could have positive effects on human health. These compounds have shown effectiveness against conditions such as obesity, diabetes, and high cholesterol, which are known risk factors for cardiovascular diseases, including stroke. Stroke is currently the second leading cause of death globally, and cerebral small vessel disease (CSVD) accounts for 20% of all strokes, and it often causes cognitive impairment and gait abnormalities in older adults. Anthocyanins and their metabolites can cross the blood–brain barrier and affect signaling pathways, gene expression, and protein function at the molecular level. In addition to their ability to enhance vascular flow, anthocyanins can also help mitigate the risk factors associated with CSVD by counteracting oxidative stress in the body. These findings exploring the potential benefits of anthocyanins for individuals with CSVD. © The Author(s) 2024.
anthocyanin; antioxidant; adult; blood brain barrier; blood flow; cerebrovascular accident; cognitive defect; controlled study; diabetic obesity; drug development; gene expression; human; hypercholesterolemia; major clinical study; male; oxidative stress; protein function; review; risk factor; signal transduction
Doctoral Program in Medical Science, Faculty of Medicine, Universitas Indonesia
This work was supported by Doctoral Program in Medical Science, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia.
Springer Science and Business Media Deutschland GmbH
11101083
Review
Q3
355
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