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Publikasi Scopus 2024 per tanggal 30 September 2024 (820 artikel)
Publikasi Scopus 2024 per tanggal 30 September 2024 (820 artikel)
Wang, Qian (59093381000); Ma, Tian (57218990871); Ding, Fangyu (57194508485); Lim, Ahyoung (57222061897); Takaya, Saho (58913455200); Saraswati, Kartika (57201491297); Sartorius, Benn (12788526800); Day, Nicholas P.J. (57708887000); Maude, Richard J. (25625222500)
Global and regional seroprevalence, incidence, mortality of, and risk factors for scrub typhus: A systematic review and meta-analysis
2024
International Journal of Infectious Diseases
146
107151
0
https://www.scopus.com/inward/record.uri?eid=2-s2.0-85199198062&doi=10.1016%2fj.ijid.2024.107151&partnerID=40&md5=7a4bece96ed13f2a72f52fa8d09c52c1
Mahidol Oxford Tropical Medicine Research Unit, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand; Centre for Tropical Medicine and Global Health, Nuffield Department of Medicine, University of Oxford, Oxford, United Kingdom; Institute of Geographic Sciences and Natural Resources Research, Chinese Academy of Sciences, Beijing, China; College of Resources and Environment, University of Chinese Academy of Sciences, Beijing, China; London School of Hygiene & Tropical Medicine, London, United Kingdom; Saw Swee Hock School of Public Health, National University of Singapore, Singapore, Singapore; Oxford University Clinical Research Unit Indonesia, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Centre for Clinical Research (UQCCR), Faculty of Medicine, University of Queensland, Brisbane, Australia; Department of Health Metric Sciences, School of Medicine, University of Washington, Seattle, United States; The Open University, Milton Keynes, United Kingdom
Objectives: Scrub typhus is underdiagnosed and underreported but emerging as a global public health problem. We aimed to provide the first comprehensive review on the seroprevalence, incidence, mortality of and risk factors for scrub typhus. Methods: We searched PubMed, Scopus, Web of Science, China National Knowledge Infrastructure and other databases. Trended incidence and median mortality were calculated and pooled seroprevalence and risk factors for scrub typhus were evaluated using the random-effects meta-analysis. Results: We included 663 articles from 29 countries/regions. The pooled seroprevalence was 10.73% (95%CI 9.47-12.13%) among healthy individuals and 22.58% (95%CI: 20.55%-24.76%) among febrile patients. Mainland China reported the highest number of cases and South Korea and Thailand had the highest incidence rates. Median mortalities were 5.00% (range: 0.00-56.00%) among hospital inpatients, 6.70% (range: 0.00-33.33%) among patients without specified admission status and 2.17% (range: 0.00-22.22%) among outpatients. The significant risk factors included agricultural work, specific vegetation exposure, other outdoor activities, risky personal health habits, and proximity to rodents, livestock, or poultry. Conclusions: Our comprehensive review elucidates the significant yet variable burden of scrub typhus across different regions, underscoring its emergence as a critical public health concern globally. © 2024 The Authors
Animals; Global Health; Humans; Incidence; Orientia tsutsugamushi; Risk Factors; Scrub Typhus; Seroepidemiologic Studies; Article; diagnostic procedure; enzyme linked immunosorbent assay; female; habit; hospital patient; human; incidence; Japan; Laos; livestock; major clinical study; meta analysis; military personnel; mortality; Papua New Guinea; poultry; quality control; risk factor; rodent; scrub typhus; seroprevalence; Solomon Islands; systematic review; vegetation; animal; epidemiology; global health; immunology; incidence; mortality; Orientia tsutsugamushi; risk factor; seroepidemiology
Wellcome Trust, WT, (220211); Wellcome Trust, WT; National Natural Science Foundation of China, NSFC, (42201497); National Natural Science Foundation of China, NSFC; Youth Innovation Promotion Association, YIPA, (2023000117); Youth Innovation Promotion Association, YIPA; NRF, (RIE2025)
Funding text 1: This research was funded in part by the Wellcome Trust [ 220211 ], National Natural Science Foundation of China [ 42201497 ], Youth Innovation Promotion Association [ 2023000117 ], and NRF International Partnership Funding Initiative [ RIE2025 ]. The funder had no role in study design, data collection, data analysis, data interpretation, or writing of this study. ; Funding text 2:
Elsevier B.V.
12019712
38964725
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