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Publikasi Scopus 2024 per tanggal 31 Januari 2024 (57 artikel)
Publikasi Scopus 2024 per tanggal 31 Januari 2024 (57 artikel)
Sukowati, Caecilia HC (26653855800); El-Khobar, Korri (55969199100); Jasirwan, Chyntia Olivia Maurine (55192478000); Kurniawan, Juferdy (57193251655); Gani, Rino Alvani (23495930300)
Stemness markers in hepatocellular carcinoma of Eastern vs. Western population: Etiology matters?
2024
Annals of Hepatology
29
1
101153
0
https://www.scopus.com/inward/record.uri?eid=2-s2.0-85173150306&doi=10.1016%2fj.aohep.2023.101153&partnerID=40&md5=974748f418af439423c1070b4116a6ef
Liver Cancer Unit, Fondazione Italiana Fegato ONLUS, AREA Science Park campus Basovizza, SS14 km 163.5, Trieste, 34149, Italy; Eijkman Research Center for Molecular Biology, National Research and Innovation Agency of Indonesia (BRIN), B.J. Habibie Building, Jl. M.H. Thamrin No. 8, Jakarta Pusat, 10340, Indonesia; Hepatobiliary Division, Medical Staff Group of Internal Medicine, Faculty of Medicine, Universitas Indonesia - Dr. Cipto Mangunkusumo General Hospital, Jl. Pangeran Diponegoro No.71, Jakarta, 10430, Indonesia
Hepatocellular carcinoma (HCC) is one of the most common cancers with a high mortality rate. HCC development is associated with its underlying etiologies, mostly caused by infection of chronic hepatitis B virus (HBV) and hepatitis C virus (HCV), alcohol, non-alcoholic fatty liver disease, and exposure to aflatoxins. These variables, together with human genetic susceptibility, contribute to HCC molecular heterogeneity, including at the cellular level. HCC initiation, tumor recurrence, and drug resistance rates have been attributed to the presence of liver cancer stem cells (CSC). This review summarizes available data regarding whether various HCC etiologies may be associated to the appearance of CSC biomarkers. It also described the genetic variations of tumoral tissues obtained from Western and Eastern populations, in particular to the oncogenic effect of HBV in the human genome. © 2023 Fundación Clínica Médica Sur, A.C.
Carcinoma, Hepatocellular; Hepatitis B; Hepatitis B virus; Hepatitis B, Chronic; Hepatitis C; Humans; Liver Neoplasms; Neoplasm Recurrence, Local; aflatoxin; aflatoxin B1; tumor marker; alcoholic fatty liver; cancer diagnosis; cancer mortality; cancer stem cell; cell stemness; disease association; DNA polymorphism; gene mutation; genetic association; genetic heterogeneity; genetic susceptibility; genetic variability; Hepatitis B virus; Hepatitis C virus; high throughput sequencing; human; liver cell carcinoma; mortality rate; nonalcoholic fatty liver; nonhuman; race difference; Review; chronic hepatitis B; complication; genetics; hepatitis B; hepatitis C; liver cell carcinoma; liver tumor; pathology; tumor recurrence
Fondazione Umberto Veronesi
CHCS is supported by 2022-2023 grant of the Fondazione Umberto Veronesi, Milan, Italy. KEEK received a fellowship of the Ministero degli Affari Esteri e della Cooperazione Internazionale (MAECI) of Italy for the Progetto Co-Tutela at the FIF.
Elsevier Espana S.L.U
16652681
37734662
Review
Q2
859
5362