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Publikasi Scopus 2024 per tanggal 31 Juli 2024 (607 artikel)
Publikasi Scopus 2024 per tanggal 31 Juli 2024 (607 artikel)
Harzif, Achmad Kemal (57191493435); Pratamasari, Sarah Miriam Ratna (59229545400); Rumapea, Costan Tryono Parulian (59229420600); Ummah, Nafi’atul (58945649100); Mutia, Heidi Dewi (57214329625); Nurbaeti, Putri (58945649200); Puspawardani, Aisyah Retno (58944793100); Wiweko, Budi (43061741400)
The efficacy of luteal phase support in women with polycystic ovary syndrome following assisted reproductive technology: a systematic review
2024
Middle East Fertility Society Journal
29
1
40
0
https://www.scopus.com/inward/record.uri?eid=2-s2.0-85199295889&doi=10.1186%2fs43043-024-00187-5&partnerID=40&md5=440e7d636e950a0e55a4289cbfcc5f68
Reproductive Immunoendocrinology Division, Department of Obstetrics and Gynecology, Faculty of Medicine Universitas Indonesia - dr. Cipto Mangunkusumo General Hospital, Jakarta, Indonesia; Yasmin IVF Clinic dr. Cipto Mangunkusumo General Hospital, Jakarta, Indonesia; Human Reproduction, Infertility, and Family Planning Cluster, Indonesia Reproductive Medicine Research and Training Center, Faculty of Medicine Universitas Indonesia, Jakarta, Indonesia; Department of Obstetrics and Gynecology, Faculty of Medicine Universitas Indonesia, Jakarta, Indonesia
Background: Polycystic ovary syndrome (PCOS) is a complex endocrine condition prevalent among a significant number of women during their reproductive years. Remarkably, 90–95% of women seeking infertility solutions due to anovulation are diagnosed with PCOS. Luteal phase support (LPS) is a crucial aspect of assisted reproductive technologies (ART). This systematic review aimed to evaluate the effectiveness of LPS in women with PCOS undergoing ART, with a focus on pregnancy rates as the primary endpoint. Materials and methods: A systematic search was conducted on EMBASE, PubMed, and Scopus databases without language restrictions. We searched for studies up to August 1, 2023. The search strategy used terms related to PCOS and LPS. Clinical trials and cohort studies involving infertile women with PCOS undergoing ART were included. The Risk of Bias 2 (ROB2) and the Newcastle-Ottawa Scale (NOS) tool were used to assess the risk of bias. Results: The review included five studies comprising a total of 818 patients. The studies used various ovulation induction medications, such as letrozole, clomiphene citrate, and human menopausal gonadotropin, in combination with different forms of progesterone for LPS (oral, intramuscular, and intravaginal). The overall results demonstrated inconsistent efficacy of LPS, with some studies showing significant improvements in pregnancy rates with LPS, while others showed no statistically significant difference. Conclusion: The systematic review suggests that LPS may improve pregnancy rates in women with PCOS undergoing ART. However, the effectiveness appears to be influenced by the choice of ovulation induction agent and the route of progesterone administration. Personalized treatment approaches considering patient response and emerging evidence are essential. © The Author(s) 2024.
Department of Obstetrics and Gynecology, Faculty of Medicine Universitas Indonesia
The authors sincerely thank the Department of Obstetrics and Gynecology, Faculty of Medicine Universitas Indonesia, for supporting this research.
Springer Science and Business Media Deutschland GmbH
11105690
Review
Q3
322
14459