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Publikasi Scopus 2024 per tanggal 31 Maret 2024 (233 artikel)
Publikasi Scopus 2024 per tanggal 31 Maret 2024 (233 artikel)
Wijaya, Meiliyana (58294618400); Surja, Sem Samuel (57209258108); Adawiyah, Robiatul (57208658742); Hariadi, Ariananda (57215705461); Setianingrum, Findra (57203061705); Rozaliyani, Anna (57203065912); Burhan, Erlina (36058554600); Tugiran, Mulyati (57218291154); Sjam, Ridhawati (23398458200); Denning, David W. (7102640098); Wahyuningsih, Retno (6507268400)
Histoplasma antigen detection in unconfirmed pulmonary tuberculosis and cross-reactivity with Aspergillus antigen in patients and in food in Jakarta, Indonesia
2024
Mycoses
67
1
e13670
0
https://www.scopus.com/inward/record.uri?eid=2-s2.0-85176139884&doi=10.1111%2fmyc.13670&partnerID=40&md5=ec5ac4e85b759b24f29492adadceeb7b
Study Program of Clinical Parasitology, Department of Parasitology, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Department of Parasitology, School of Medicine and Health Sciences, Atma Jaya Catholic University of Indonesia, Jakarta, Indonesia; Department of Parasitology, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Indonesia Pulmonary Mycoses Centre (IPMC), Faculty of Medicine Universitas Indonesia and Persahabatan National Respiratory Referral Hospital, Jakarta, Indonesia; Master's Programme in Biomedical Sciences, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Infectious Diseases and Immunology Research Center (IDIRC), Indonesian Medical Education and Research Institute (IMERI), Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Department of Pulmonology and Respiratory Medicine, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Persahabatan National Respiratory Referral Hospital, Jakarta, Indonesia; Manchester Fungal Infection Group, Faculty of Biology, Medicine and Health, University of Manchester, Manchester Academic Health Science Centre, Manchester, United Kingdom; Department of Parasitology, Faculty of Medicine, Universitas Kristen Indonesia, Jakarta, Indonesia
Purpose: H. capsulatum is endemic in Indonesia, but the value of Histoplasma antigen detection has not been studied. Patients and Methods: Histoplasma galactomannan (GM) ELISA was applied to sera of patients with unproven pulmonary tuberculosis (TB) and patients with a positive Aspergillus GM. Both Histoplasma and Aspergillus GM tests were performed to determine any possible cross-reaction with certain foods. Results: Fourteen of 122 (11.5%) sera of patients with newly diagnosed clinical TB were positive for Histoplasma GM. The positivity rate in the serum of patients 5–6 and 12 months after TB diagnosis was 3.8% and 3.5%, respectively. Of 88 positive Aspergillus GM sera, 63 (71.6%) were also positive for Histoplasma GM. All tested foods were positive for Aspergillus GM, while 65% of foods were positive for Histoplasma GM. Conclusion: Galactomannan is widespread in sera and food in Jakarta, possibly related to food consumption. Histoplasma and Aspergillus antigen detection for the diagnosis will require additional means of confirming the diagnosis; negative tests may be more helpful for ruling out invasive histoplasmosis and aspergillosis. © 2023 Wiley-VCH GmbH. Published by John Wiley & Sons Ltd.
Antigens, Fungal; Aspergillosis; Aspergillus; Histoplasma; Histoplasmosis; Humans; Indonesia; Mannans; Sensitivity and Specificity; fungus antigen; galactomannan; fungus antigen; mannan; adult; antigen detection; Article; Aspergillus; controlled study; cross reaction; enzyme linked immunosorbent assay; female; Histoplasma; histoplasmosis; human; Indonesia; infant; lung tuberculosis; male; middle aged; nonhuman; statistically significant result; aspergillosis; Histoplasma; histoplasmosis; sensitivity and specificity
Medical Research Council, MRC, (MR/P017622/1)
RW received a research grant from Dana Ilmu Pengetahuan Indonesia/Lembaga Pengelolaan Dana Pendidikan (DIPI/LPDP) and DWD from the UK Medical Research Council with contract number MR/P017622/1. We also thank IMMY, Norman, Oklahoma, USA, for providing a antigen detection kit for this study. Histoplasma
John Wiley and Sons Inc
09337407
37897135
Article
Q1
1059
3836