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Publikasi Scopus 2024 per tanggal 31 Maret 2024 (233 artikel)
Publikasi Scopus 2024 per tanggal 31 Maret 2024 (233 artikel)
‘ilmi, Laily ‘U.N. (58804130200); Lestari, Tita D. (57207314733); Widjiati (57219597156); Safitri, Erma (57189090514); Restiadi, Tjuk I. (57202455641); Mafruchati, Maslichah (57214464266); Amrullah, Muhammad F. (58571961400); Khairullah, Aswin R. (57212026505); Kurniawan, Shendy C. (57863649900); Abani, Salsabilla (57218517547); Hasib, Abdullah (57219295438); Samodra, Muhammad E.E. (58803899500); Silaen, Otto S.M. (57219408428)
Supplementation of alpha lipoic acid on Kacang goat (Capra hircus) oocyte to the growth of GDF-9 and BMP-15
2024
Journal of Advanced Veterinary Research
14
1
135
138
3
0
https://www.scopus.com/inward/record.uri?eid=2-s2.0-85181880203&partnerID=40&md5=0cda42ac17a1ed308073aa4c9afd8b53
Master Program of Reproductive Biology, Faculty of Veterinary Medicine, Universitas Airlangga, Jl. Dr. Ir. H. Soekarno, Kampus C Mulyorejo, East Java, Surabaya, 60115, Indonesia; Division of Veterinary Reproduction, Faculty of Veterinary Medicine, Universitas Airlangga, Jl. Dr. Ir. H. Soekarno, Kampus C Mulyorejo, East Java, Surabaya, 60115, Indonesia; Division of Veterinary Anatomy, Faculty of Veterinary Medicine, Universitas Airlangga, Jl. Dr. Ir. H. Soekarno, Kampus C Mulyorejo, East Java, Surabaya, 60115, Indonesia; Division of Animal Husbandry, Faculty of Veterinary Medicine, Universitas Airlangga, Jl. Dr. Ir. H. Soekarno, Kampus C Mulyorejo, East Java, Surabaya, 60115, Indonesia; Master Program of Animal Sciences, Department of Animal Sciences, Specialisation in Molecule, Cell and Organ Functioning, Wageningen University and Research, Wageningen, 6708 PB, Netherlands; School of Agriculture and Food Sustainability, The University of Queensland, Gatton, QLD 4343, QLD, Australia; Bachelor Program of Veterinary Medicine, Faculty of Veterinary Medicine, Universitas Airlangga, Jl. Dr. Ir. H. Soekarno, Kampus C Mulyorejo, East Java, Surabaya, 60115, Indonesia; Doctoral Program in Biomedical Science, Faculty of Medicine, Universitas Indonesia, Jl. Salemba Raya No. 6 Senen, Jakarta, 10430, Indonesia
The application of assisted reproductive technology by mass-producing embryos is to maintain genetic resistance, increase productivity and livestock populations in a short time with maximum quality. Oocyte In vitro Maturation (IVM) is a crucial stage of In vitro Fertilization (IVF) implementation to increase the quantity and quality of livestock genetic trait through in In vitro Embryo Production (IVP). GDF-9 and BMP-15 expression are in the family of Transforming Growth Factor Beta (TGF-β) which are known to regulate oocyte and cumulus cell development in mammals. This study’s objective was to investigate the effects of Alpha Lipoic Acid (ALA) on IVM media of Kacang goat (Capra hircus) oocytes. This research was an experimental study design consist-ing of 3 treatment groups: (P0) the control group, (P1) 25 µM/L ALA supplementation and (P2) 50 µM/L ALA supplementation. This study used 261 COCs which were 22 hours matured in vitro at 38.5°C, 98% humidity, and 5% CO2. GDF-9 and BMP-15 expression data were statistically tested with a significance of p<0.05. Immunocy-tochemistry showed the expression value of GDF-9 (2.86±1.06, 4.29±1.79 and 8.29±2.69). BMP-15 expression values (2.57±1.39, 5.71±3.72 and 11.43±1.51). The results of the study showed that supplementation with ALA on maturation media at a dose of 50 µM/L toward the maturation level and increased GDF-9 and BMP-15 expression in vitro maturation of Kacang goat oocyte. © 2011-2024 Journal of Advanced Veterinary Research. All rights reserved.
Assiut University, Faculty of Veterinary Medicine, Department of Animal Medicine
20906269
Article
Q3
187
19867