Publikasi Scopus 2024 per tanggal 31 Mei 2024 (409 artikel)

Authors

Sánchez K.L.; Baird J.K.; Nielsen A.; Nurillah A.; Agustina F.; Komara; Fadilah F.; Prameswari W.; Nugraha R.T.P.; Saputra S.; Nurkanto A.; Dharmayanthi A.B.; Pratama R.; Exploitasia I.; Greenwood A.D.

Author_Full_Names

Sánchez, Karmele Llano (57200632467); Baird, John Kevin (15921267800); Nielsen, Aileen (57221277141); Nurillah, Andini (57912908400); Agustina, Fitria (57912690600); Komara (58894822000); Fadilah, Fina (58895037400); Prameswari, Wendi (57191862252); Nugraha, Raden Taufiq Purna (57191611489); Saputra, Sugiyono (57076979100); Nurkanto, Arif (36025675800); Dharmayanthi, Anik Budhi (57193719895); Pratama, Rahadian (57222242146); Exploitasia, Indra (57300385400); Greenwood, Alex D. (7102457657)

Author S Id

57200632467; 15921267800; 57221277141; 57912908400; 57912690600; 58894822000; 58895037400; 57191862252; 57191611489; 57076979100; 36025675800; 57193719895; 57222242146; 57300385400; 7102457657

Title

Naturally acquired immunity to Plasmodium pitheci in Bornean orangutans (Pongo pygmaeus)

Year

2024

Source Title

Parasitology

Volume

151

Issue

Art No

Page Start

380

Page End

389

Page Count

Cited By

Link

https://www.scopus.com/inward/record.uri?eid=2-s2.0-85185520183&doi=10.1017%2fS0031182024000155&partnerID=40&md5=11f083d01fc6e6c6b92d74e29d0c876d

Affiliations

IAR Indonesia Foundation, Yayasan Inisiasi Alam Rehabilitasi Indonesia (YIARI), Sinarwangi, West Java, Bogor, Indonesia; International Animal Rescue, Uckfield, United Kingdom; School of Veterinary Medicine, Freie Universität, Berlin, Germany; Oxford University Clinical Research Unit-Indonesia, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Centre for Tropical Medicine and Global Health, Nuffield Department of Medicine, University of Oxford, Oxford, United Kingdom; Center for Law and Economics, ETH Zurich, Zurich, Switzerland; Research Center for Applied Zoology, National Research and Innovation Agency (BRIN), Jakarta, Indonesia; Research Center for Biosystematics and Evolution, National Research and Innovation Agency (BRIN), Jakarta, Indonesia; Center for Biomedical Research, Research Organization for Health, National Research and Innovation Agency (BRIN), Jakarta, Indonesia; Ministry of Environment and Forestry the Republic of Indonesia, Jakarta, Indonesia; Department of Wildlife Diseases, Leibniz Institute for Zoo and Wildlife Research, Berlin, Germany

Authors With Affiliations

Sánchez K.L., IAR Indonesia Foundation, Yayasan Inisiasi Alam Rehabilitasi Indonesia (YIARI), Sinarwangi, West Java, Bogor, Indonesia, International Animal Rescue, Uckfield, United Kingdom, School of Veterinary Medicine, Freie Universität, Berlin, Germany; Baird J.K., Oxford University Clinical Research Unit-Indonesia, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia, Centre for Tropical Medicine and Global Health, Nuffield Department of Medicine, University of Oxford, Oxford, United Kingdom; Nielsen A., Center for Law and Economics, ETH Zurich, Zurich, Switzerland; Nurillah A., IAR Indonesia Foundation, Yayasan Inisiasi Alam Rehabilitasi Indonesia (YIARI), Sinarwangi, West Java, Bogor, Indonesia; Agustina F., IAR Indonesia Foundation, Yayasan Inisiasi Alam Rehabilitasi Indonesia (YIARI), Sinarwangi, West Java, Bogor, Indonesia; Komara, IAR Indonesia Foundation, Yayasan Inisiasi Alam Rehabilitasi Indonesia (YIARI), Sinarwangi, West Java, Bogor, Indonesia; Fadilah F., IAR Indonesia Foundation, Yayasan Inisiasi Alam Rehabilitasi Indonesia (YIARI), Sinarwangi, West Java, Bogor, Indonesia; Prameswari W., IAR Indonesia Foundation, Yayasan Inisiasi Alam Rehabilitasi Indonesia (YIARI), Sinarwangi, West Java, Bogor, Indonesia; Nugraha R.T.P., Research Center for Applied Zoology, National Research and Innovation Agency (BRIN), Jakarta, Indonesia; Saputra S., Research Center for Applied Zoology, National Research and Innovation Agency (BRIN), Jakarta, Indonesia; Nurkanto A., Research Center for Biosystematics and Evolution, National Research and Innovation Agency (BRIN), Jakarta, Indonesia; Dharmayanthi A.B., Research Center for Biosystematics and Evolution, National Research and Innovation Agency (BRIN), Jakarta, Indonesia; Pratama R., Center for Biomedical Research, Research Organization for Health, National Research and Innovation Agency (BRIN), Jakarta, Indonesia; Exploitasia I., Ministry of Environment and Forestry the Republic of Indonesia, Jakarta, Indonesia; Greenwood A.D., School of Veterinary Medicine, Freie Universität, Berlin, Germany, Department of Wildlife Diseases, Leibniz Institute for Zoo and Wildlife Research, Berlin, Germany

Abstract

Naturally acquired immunity to the different types of malaria in humans occurs in areas of endemic transmission and results in asymptomatic infection of peripheral blood. The current study examined the possibility of naturally acquired immunity in Bornean orangutans, Pongo pygmaeus, exposed to endemic Plasmodium pitheci malaria. A total of 2140 peripheral blood samples were collected between January 2017 and December 2022 from a cohort of 135 orangutans housed at a natural forested Rescue and Rehabilitation Centre in West Kalimantan, Indonesia. Each individual was observed for an average of 4.3 years during the study period. Blood samples were examined by microscopy and polymerase chain reaction for the presence of plasmodial parasites. Infection rates and parasitaemia levels were measured among age groups and all 20 documented clinical malaria cases were reviewed to estimate the incidence of illness and risk ratios among age groups. A case group of all 17 individuals that had experienced clinical malaria and a control group of 34 individuals having an event of >2000 parasites μL−1 blood but with no outward or clinical sign of illness were studied. Immature orangutans had higher-grade and more frequent parasitaemia events, but mature individuals were more likely to suffer from clinical malaria than juveniles. The case orangutans having patent clinical malaria were 256 times more likely to have had no parasitaemia event in the prior year relative to asymptomatic control orangutans. The findings are consistent with rapidly acquired immunity to P. pitheci illness among orangutans that wanes without re-exposure to the pathogen. © The Author(s), 2024. Published by Cambridge University Press. This is an Open Access article, distributed under the terms of the Creative Commons Attribution licence (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted re-use, distribution and reproduction, provided the original article is properly cited.

Author Keywords

malaria; naturally acquired immunity; One Health-One Welfare; orangutan; orangutan conservation; Plasmodium pitheci; veterinary parasitology

Index Keywords

Animals; Forests; Humans; Indonesia; Malaria; Plasmodium; Pongo; Pongo pygmaeus; adaptive immunity; adult; age; Article; blood sampling; clinical feature; clinical observation; cohort analysis; controlled study; female; infection rate; malaria; male; microscopy; nonhuman; orangutan; parasitemia; Plasmodium; Plasmodium pitheci; polymerase chain reaction; Pongo pygmaeus; animal; forest; human; Indonesia; malaria; Pongo pygmaeus

Funding Details

Funding Text

Publisher

Cambridge University Press

Issn

00311820

Isbn

Pubmed Id

38361461

Document Type

Article

Sjr Best Quartile

Sjr

683

Sjr Rank

7344